What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Exercise for acutely hospitalised older medical patients
- Authors
- Hartley, P. Keating, J. L. Jeffs, K. J. Raymond, M. J. Smith, T. O
- Year
- 2022
- Journal
- Cochrane Database Syst Rev
- Abstract
BACKGROUND: Approximately 30% of hospitalised older adults experience hospital-associated functional decline. Exercise interventions that promote in-hospital activity may prevent deconditioning and thereby maintain physical function during hospitalisation. This is an update of a Cochrane Review first published in 2007. OBJECTIVES: To evaluate the benefits and harms of exercise interventions for acutely hospitalised older medical inpatients on functional ability, quality of life (QoL), participant global assessment of success and adverse events compared to usual care or a sham-control intervention. SEARCH METHODS: We used standard, extensive Cochrane search methods. The latest search date was May 2021. SELECTION CRITERIA: We included randomised or quasi-randomised controlled trials evaluating an in-hospital exercise intervention in people aged 65 years or older admitted to hospital with a general medical condition. We excluded people admitted for elective reasons or surgery. DATA COLLECTION AND ANALYSIS: We used standard Cochrane methods. Our major outcomes were 1. independence with activities of daily living; 2. functional mobility; 3. new incidence of delirium during hospitalisation; 4. QoL; 5. number of falls during hospitalisation; 6. medical deterioration during hospitalisation and 7. participant global assessment of success. Our minor outcomes were 8. death during hospitalisation; 9. musculoskeletal injuries during hospitalisation; 10. hospital length of stay; 11. new institutionalisation at hospital discharge; 12. hospital readmission and 13. walking performance. We used GRADE to assess certainty of evidence for each major outcome. We categorised exercise interventions as: rehabilitation-related activities (interventions designed to increase physical activity or functional recovery, but did not follow a specified exercise protocol); structured exercise (interventions that included an exercise intervention protocol but did not include progressive resistance training); and progressive resistance exercise (interventions that included an element of progressive resistance training). MAIN RESULTS: We included 24 studies (nine rehabilitation-related activity interventions, six structured exercise interventions and nine progressive resistance exercise interventions) with 7511 participants. All studies compared exercise interventions to usual care; two studies, in addition to usual care, used sham interventions. Mean ages ranged from 73 to 88 years, and 58% of participants were women. Several studies were at high risk of bias. The most common domain assessed at high risk of bias was measurement of the outcome, and five studies (21%) were at high risk of bias arising from the randomisation process. Exercise may have no clinically important effect on independence in activities of daily living at discharge from hospital compared to controls (16 studies, 5174 participants; low-certainty evidence). Five studies used the Barthel Index (scale: 0 to 100, higher scores representing greater independence). Mean scores at discharge in the control groups ranged from 42 to 96 points, and independence in activities of daily living was 1.8 points better (0.43 worse to 4.12 better) with exercise compared to controls. The minimally clinical important difference (MCID) is estimated to be 11 points. We are uncertain regarding the effect of exercise on functional mobility at discharge from the hospital compared to controls (8 studies, 2369 participants; very low-certainty evidence). Three studies used the Short Physical Performance Battery (SPPB) (scale: 0 to 12, higher scores representing better function) to measure functional mobility. Mean scores at discharge in the control groups ranged from 3.7 to 4.9 points on the SPPB, and the estimated effect of the exercise interventions was 0.78 points better (0.02 worse to 1.57 better). A change of 1 point on the SPPB represents an MCID. We are uncertain regarding the effect of exercise on the incidence of delirium during hospitalisation compared to controls (7 trials, 2088 participants; very low-certainty evidence). The incidence of delirium during hospitalisation was 88/1091 (81 per 1000) in the control group compared with 70/997 (73 per 1000; range 47 to 114) in the exercise group (RR 0.90, 95% CI 0.58 to 1.41). Exercise interventions may result in a small clinically unimportant improvement in QoL at discharge from the hospital compared to controls (4 studies, 875 participants; low-certainty evidence). Mean QoL on the EuroQol 5 Dimensions (EQ-5D) visual analogue scale (VAS) (scale: 0 to 100, higher scores representing better QoL) ranged between 48.9 and 64.7 in the control group at discharge from the hospital, and QoL was 6.04 points better (0.9 better to 11.18 better) with exercise. A change of 10 points on the EQ-5D VAS represents an MCID. No studies measured participant global assessment of success. Exercise interventions did not affect the risk of falls during hospitalisation (moderate-certainty evidence). The incidence of falls was 31/899 (34 per 1000) in the control group compared with 31/888 (34 per 1000; range 20 to 57) in the exercise group (RR 0.99, 95% CI 0.59 to 1.65). We are uncertain regarding the effect of exercise on the incidence of medical deterioration during hospitalisation (very low-certainty evidence). The incidence of medical deterioration in the control group was 101/1417 (71 per 1000) compared with 96/1313 (73 per 1000; range 44 to 120) in the exercise group (RR 1.02, 95% CI 0.62 to 1.68). Subgroup analyses by different intervention categories and by the use of a sham intervention were not meaningfully different from the main analyses. AUTHORS’ CONCLUSIONS: Exercise may make little difference to independence in activities of daily living or QoL, but probably does not result in more falls in older medical inpatients. We are uncertain about the effect of exercise on functional mobility, incidence of delirium and medical deterioration. Certainty of evidence was limited by risk of bias and inconsistency. Future primary research on the effect of exercise on acute hospitalisation could focus on more consistent and uniform reporting of participant’s characteristics including their baseline level of functional ability, as well as exercise dose, intensity and adherence that may provide an insight into the reasons for the observed inconsistencies in findings.
- PMID
- Keywords
Aged
Aged, 80 and over
Female
Humans
Male
Activities of Daily Living
*Delirium/epidemiology
Exercise
*Quality of Life
- Page(s)
- Volume
- Issue
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| Diagnosis and management of delirium near the end of life. | Casarett DJ, Inouye SK, | Annals of internal medicine | 2001 |
Adult, Clinical Laboratory Techniques, Combined Modality Therapy, Delirium, diagnosis, Female, Humans, Ovarian Neoplasms, psychology, Physical Examination, Terminal Care, methods, Terminally Ill, psychology |
| Hypocortisolemia and delirium in an older patient. | Cunha UG, Faria AC, de F Alves VX, Rigueirinho SA | Journal of the American Geriatrics Society | 2001 |
Activities of Daily Living, Aged, Anti-Inflammatory Agents, pharmacology, Delirium, blood, Diarrhea, blood, Geriatric Assessment, Humans, Hydrocortisone, deficiency, Male, Mental Status Schedule, Prednisone, pharmacology, Vomiting, blood |
| Clinical and ethical questions concerning delirium study on patients with advanced cancer. | Davis MP, Walsh D | Archives of internal medicine | 2001 |
Delirium, drug therapy, Ethics, Medical, Humans, Neoplasms, complications, Palliative Care |
| Delirium in an intensive care unit: a study of risk factors. | Dubois MJ, Bergeron N, Dumont M, Dial S, Skrobik Y | Intensive care medicine | 2001 |
Analysis of Variance, Delirium, complications, Female, Humans, Intensive Care Units, Length of Stay, Logistic Models, Male, Middle Aged, Multivariate Analysis, Odds Ratio, Prospective Studies, Quebec, epidemiology, Risk Factors |
| Delirium before and after operation for femoral neck fracture. | Edlund A, Lundström M, Brännström B, Bucht G, Gustafson Y | Journal of the American Geriatrics Society | 2001 |
Aged, Aged, 80 and over, Chi-Square Distribution, Delirium, epidemiology, Female, Femoral Neck Fractures, surgery, Humans, Incidence, Logistic Models, Male, Prospective Studies, Risk Factors |
| Validity and reliability of the Portuguese version of the Confusion Assessment Method (CAM) for the detection of delirium in the elderly. | Fabbri RM, Moreira MA, Garrido R, Almeida OP | Arquivos de neuro-psiquiatria | 2001 |
Chi-Square Distribution, Confidence Intervals, Confusion, diagnosis, Delirium, diagnosis, Female, Humans, Male, Mental Status Schedule, standards, Odds Ratio, Psychiatric Status Rating Scales, Questionnaires, Reproducibility of Results, Sensitivity and Specificity |
| Delirium in elderly patients: an overview of the state of the science. | Foreman MD, Wakefield B, Culp K, Milisen K | Journal of gerontological nursing | 2001 |
Aged, Delirium, diagnosis, Humans, Nursing Assessment |
| Clinical signs of ICU syndrome/delirium: an observational study. | Granberg-Axèll A, Bergbom I, Lundberg D | Intensive & critical care nursing : the official journal of the British Association of Critical Care Nurses | 2001 |
Delirium, diagnosis, Humans, Inpatients, psychology, Intensive Care Units, Intubation, Intratracheal, Orientation, Syndrome |
| Depression or hypoactive delirium? A report of ciprofloxacin-induced mental disorder in a patient with chronic obstructive pulmonary disease. | Grassi L, Biancosino B, Pavanati M, Agostini M, Manfredini R | Psychotherapy and psychosomatics | 2001 |
Anti-Infective Agents, adverse effects, Ciprofloxacin, adverse effects, Delirium, chemically induced, Depression, chemically induced, Diagnosis, Differential, Female, Humans, Lung Diseases, Obstructive, drug therapy, Middle Aged |
| Assessing confused patients. | Johnson MH | Journal of neurology, neurosurgery, and psychiatry | 2001 |
Confusion, diagnosis, Delirium, diagnosis |
| Severity and course of delirium in medically hospitalized nursing facility residents. | Kelly KG, Zisselman M, Cutillo-Schmitter T, Reichard R, Payne D, Denman SJ | The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry | 2001 |
Aged, Aged, 80 and over, Analysis of Variance, Chi-Square Distribution, Delirium, diagnosis, Female, Follow-Up Studies, Frail Elderly, Homes for the Aged, Hospitalization, Humans, Male, Nursing Homes, Philadelphia, epidemiology, Prognosis, Risk Factors, Severity of Illness Index, Treatment Outcome |
| An open pilot trial of olanzapine for delirium in the Korean population. | Kim KS, Pae CU, Chae JH, Bahk WM, Jun T | Psychiatry and clinical neurosciences | 2001 |
Adult, Aged, Benzodiazepines, Cross-Cultural Comparison, Delirium, drug therapy, Dose-Response Relationship, Drug, Drug Administration Schedule, Female, Humans, Korea, Male, Middle Aged, Pirenzepine, adverse effects, Treatment Outcome |
| Benefits of psychiatric consultation-liaison nurse interventions for older hospitalized patients and their nurses. | Kurlowicz LH | Archives of psychiatric nursing | 2001 |
Aged, Aged, 80 and over, Cohort Studies, Delirium, diagnosis, Depressive Disorder, Major, diagnosis, Hospitalization, Hospitals, Psychiatric, Humans, Middle Aged, Nurse-Patient Relations, Psychiatric Nursing, Psychiatry, Questionnaires, Referral and Consultation, Retrospective Studies |
| Detection of delirium using the confusion assessment method. | Laplante J, Cole MG | Journal of gerontological nursing | 2001 |
Aged, Aged, 80 and over, Confusion, Delirium, diagnosis, Disease Progression, Female, Geriatric Nursing, methods, Hospitalization, Humans, Male, Monitoring, Physiologic, methods, Neurologic Examination, methods, Nursing Care, Psychological Tests, standards, Sensitivity and Specificity, Severity of Illness Index |
| Preoperative risk factors for postoperative delirium. | Litaker D, Locala J, Franco K, Bronson DL, Tannous Z | General hospital psychiatry | 2001 |
Age Factors, Aged, Alcohol Withdrawal Delirium, epidemiology, Analgesics, Opioid, administration & dosage, Cognition Disorders, Delirium, diagnosis, Female, Humans, Incidence, Male, Middle Aged, Odds Ratio, Ohio, epidemiology, Population Surveillance, Postoperative Complications, Prospective Studies, Psychiatric Status Rating Scales, Risk Factors, Surgical Procedures, Elective, adverse effects |
| Reducing delirium after hip fracture: a randomized trial. | Marcantonio ER, Flacker JM, Wright RJ, Resnick NM | Journal of the American Geriatrics Society | 2001 |
Activities of Daily Living, Aged, Aged, 80 and over, Algorithms, Delirium, classification, Female, Geriatric Assessment, Geriatrics, methods, Hip Fractures, surgery, Humans, Incidence, Length of Stay, statistics & numerical data, Male, Mental Status Schedule, Postoperative Care, methods, Postoperative Complications, classification, Preoperative Care, methods, Prospective Studies, Questionnaires, Referral and Consultation, Severity of Illness Index, Single-Blind Method |
| Clinical utility and validation of the Japanese version of Memorial Delirium Assessment Scale in a psychogeriatric inpatient setting. | Matsuoka Y, Miyake Y, Arakaki H, Tanaka K, Saeki T, Yamawaki S | General hospital psychiatry | 2001 |
Aged, Aged, 80 and over, Alzheimer Disease, diagnosis, Cross-Cultural Comparison, Delirium, diagnosis, Female, Humans, Japan, Language, Male, Neuropsychological Tests, statistics & numerical data, Psychiatric Department, Hospital, Psychometrics, Reproducibility of Results |
| Environmental risk factors for delirium in hospitalized older people. | McCusker J, Cole M, Abrahamowicz M, Han L, Podoba JE, Ramman-Haddad L | Journal of the American Geriatrics Society | 2001 |
Aged, Analysis of Variance, Delirium, etiology, Environment, Female, Geriatric Assessment, Hospitalization, Hospitals, Community, Humans, Male, Prospective Studies, Regression Analysis, Risk Factors, Sensitivity and Specificity, Severity of Illness Index, Social Isolation |
| Delirium in older medical inpatients and subsequent cognitive and functional status: a prospective study. | McCusker J, Cole M, Dendukuri N, Belzile E, Primeau F | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne | 2001 |
Activities of Daily Living, Aged, Aged, 80 and over, Cognition Disorders, epidemiology, Confounding Factors (Epidemiology), Delirium, complications, Dementia, complications, Female, Geriatric Assessment, Hospitalization, Humans, Incidence, Institutionalization, Logistic Models, Male, Prevalence, Prognosis, Prospective Studies, Psychiatric Status Rating Scales, Psychomotor Disorders, epidemiology, Risk Factors, Severity of Illness Index |
| Delirium: optimising management. | Meagher DJ | BMJ (Clinical research ed.) | 2001 |
Acute Disease, Aged, Antipsychotic Agents, therapeutic use, Benzodiazepines, adverse effects, Cholinergic Antagonists, adverse effects, Comorbidity, Delirium, diagnosis, Environment, Humans, Narcotics, adverse effects, Postoperative Complications, Psychological Tests, Risk Factors, Stress, Psychological |
| Delirium episode as a sign of undetected dementia among community dwelling elderly subjects. | Meagher D | Journal of neurology, neurosurgery, and psychiatry | 2001 |
Aged, Aging, physiology, Delirium, physiopathology, Dementia, diagnosis, Finland, Follow-Up Studies, Humans, Neuropsychological Tests |
| A nurse-led interdisciplinary intervention program for delirium in elderly hip-fracture patients. | Milisen K, Foreman MD, Abraham IL, De Geest S, Godderis J, Vandermeulen E, Fischler B, Delooz HH, Spiessens B, Broos PL | Journal of the American Geriatrics Society | 2001 |
Activities of Daily Living, Age Distribution, Age Factors, Aged, Aged, 80 and over, Delirium, classification, Female, Geriatric Assessment, Geriatric Nursing, organization & administration, Hip Fractures, surgery, Humans, Incidence, Length of Stay, statistics & numerical data, Male, Nurse Clinicians, organization & administration, Nursing Evaluation Research, Patient Care Team, organization & administration, Postoperative Complications, classification, Program Evaluation, Prospective Studies, Risk Factors, Severity of Illness Index |
| Evaluation of the Confusion Assessment Method (CAM) as a screening tool for delirium in the emergency room. | Monette J, Galbaud du Fort G, Fung SH, Massoud F, Moride Y, Arsenault L, Afilalo M | General hospital psychiatry | 2001 |
Aged, Alzheimer Disease, diagnosis, Confusion, Delirium, diagnosis, Emergency Service, Hospital, Female, Humans, Interview, Psychological, Male, Neuropsychological Tests, statistics & numerical data, Observer Variation, Prospective Studies, Psychometrics, Quebec, Reproducibility of Results |
| Communication Capacity Scale and Agitation Distress Scale to measure the severity of delirium in terminally ill cancer patients: a validation study. | Morita T, Tsunoda J, Inoue S, Chihara S, Oka K | Palliative medicine | 2001 |
Adult, Aged, Aged, 80 and over, Anxiety, etiology, Communication, Delirium, diagnosis, Female, Humans, Male, Middle Aged, Neoplasms, psychology, Observation, Psychometrics, Severity of Illness Index, Terminally Ill, psychology |
| Association of plasma free-3-methoxy-4-hydroxyphenyl (ethylene)glycol, natural killer cell activity and delirium in postoperative patients. | Nakamura J, Yoshimura R, Okuno T, Ueda N, Hachida M, Yasumoto K, Egami H, Maeda H, Nishi M, Aoyagi S | International clinical psychopharmacology | 2001 |
Aged, Cardiovascular Diseases, blood, Chromatography, High Pressure Liquid, Delirium, blood, Female, Humans, Killer Cells, Natural, metabolism, Male, Methoxyhydroxyphenylglycol, blood, Middle Aged, Postoperative Period, Prospective Studies, Statistics, Nonparametric |
| Delirium in the non-demented oldest old in the general population: risk factors and prognosis. | Rahkonen T, Eloniemi-Sulkava U, Halonen P, Verkkoniemi A, Niinistö L, Notkola IL, Sulkava R | International journal of geriatric psychiatry | 2001 |
Aged, Aged, 80 and over, Cognition Disorders, Delirium, diagnosis, Dementia, diagnosis, Female, Finland, epidemiology, Humans, Hypertension, Incidence, Male, Mental Status Schedule, Odds Ratio, Population Surveillance, Prognosis, Prospective Studies, Risk Factors |
| Prevalence, detection and treatment of anxiety, depression, and delirium in the adult critical care unit. | Rincon HG, Granados M, Unutzer J, Gomez M, Duran R, Badiel M, Salas C, Martinez J, Mejia J, Ordoñez C, Florez N, Rosso F, Echeverri P | Psychosomatics | 2001 |
Adolescent, Adult, Aged, Aged, 80 and over, Alcoholism, diagnosis, Anxiety, diagnosis, Colombia, epidemiology, Critical Care, standards, Delirium, diagnosis, Depression, diagnosis, Drug Utilization, statistics & numerical data, Female, Humans, Intensive Care Units, standards, Male, Middle Aged, Prevalence, Prospective Studies, Psychotropic Drugs, therapeutic use |
| Hyperactivity in the hypothalamic-pituitary-adrenal axis in demented patients with delirium. | Robertsson B, Blennow K, Bråne G, Edman A, Karlsson I, Wallin A, Gottfries CG | International clinical psychopharmacology | 2001 |
Aged, Alzheimer Disease, diagnosis, Arousal, physiology, Delirium, diagnosis, Dementia, diagnosis, Dexamethasone, diagnostic use, Female, Humans, Hydrocortisone, blood, Hypothalamo-Hypophyseal System, physiopathology, Male, Middle Aged, Pituitary-Adrenal System, physiopathology |
| Assessment of delirium in advanced cancer: the use of the bedside confusion scale. | Sarhill N, Walsh D, Nelson KA, LeGrand S, Davis MP | The American journal of hospice & palliative care | 2001 |
Aged, Case-Control Studies, Causality, Confusion, classification, Delirium, classification, Female, Geriatric Assessment, Humans, Male, Mass Screening, methods, Middle Aged, Neoplasms, complications, Neurologic Examination, methods, Patients’ Rooms, Pilot Projects, Prevalence, Prospective Studies, Severity of Illness Index, Time Factors |
| Early recognition of delirium: review of the literature. | Schuurmans MJ, Duursma SA, Shortridge-Baggett LM | Journal of clinical nursing | 2001 |
Age Distribution, Aged, Delirium, diagnosis, Diagnosis, Differential, Emergencies, Geriatric Assessment, Humans, Incidence, Mass Screening, methods, Nursing Assessment, methods, Risk Factors, Time Factors, Total Quality Management |
| Postoperative delirium and melatonin levels in elderly patients. | Shigeta H, Yasui A, Nimura Y, Machida N, Kageyama M, Miura M, Menjo M, Ikeda K | American journal of surgery | 2001 |
Abdomen, surgery, Aged, Aged, 80 and over, Delirium, blood, Female, Humans, Male, Melatonin, blood, Postoperative Complications, blood |
| A survey on the drug therapy for delirium. | Someya T, Endo T, Hara T, Yagi G, Suzuki J | Psychiatry and clinical neurosciences | 2001 |
Antipsychotic Agents, therapeutic use, Delirium, drug therapy, Drug Approval, Drug Utilization Review, Haloperidol, therapeutic use, Humans, Japan, Psychiatric Department, Hospital, standards, Questionnaires |
| Factors associated with sudden death of individuals requiring restraint for excited delirium. | Stratton SJ, Rogers C, Brickett K, Gruzinski G | The American journal of emergency medicine | 2001 |
Adult, Alcoholism, complications, Amphetamine-Related Disorders, complications, Autopsy, Body Mass Index, Cocaine-Related Disorders, complications, Death, Sudden, etiology, Delirium, chemically induced, Emergency Medical Services, Heart Arrest, etiology, Heart Rate, Humans, Marijuana Abuse, complications, Myocardium, pathology, Obesity, complications, Posture, Restraint, Physical, Retrospective Studies, Risk Factors |
| Anxiety, delirium, and pain in the intensive care unit. | Szokol JW, Vender JS | Critical care clinics | 2001 |
Analgesics, therapeutic use, Anxiety, drug therapy, Clinical Competence, Critical Illness, psychology, Delirium, drug therapy, Humans, Hypnotics and Sedatives, therapeutic use, Intensive Care Units, standards, Pain, drug therapy, Quality of Health Care, Respiration, Artificial |
| Acute confusion in terminally ill hospitalized patients. | Wakefield B, Johnson JA | Journal of gerontological nursing | 2001 |
Acute Disease, Aged, Confusion, etiology, Delirium, etiology, Hospitalization, Humans, Male, Neoplasms, psychology, Terminally Ill, psychology |
| Delirious mania in the elderly. | Weintraub D, Lippmann S | International journal of geriatric psychiatry | 2001 |
Aged, Antipsychotic Agents, administration & dosage, Bipolar Disorder, diagnosis, Confusion, etiology, Delirium, diagnosis, Diagnosis, Differential, Drug Therapy, Combination, Female, Humans, Male, Psychomotor Agitation, etiology, Sleep Initiation and Maintenance Disorders, etiology, Syndrome, Treatment Outcome |
| Effectiveness of interventions to prevent delirium in hospitalized patients: a systemic review. | Zeleznik J | Journal of the American Geriatrics Society | 2001 |
Delirium, etiology, Hospitalization, Humans, Randomized Controlled Trials as Topic, Risk Factors |
| Acute confusional state in the elderly following hip surgery: incidence, risk factors and complications. | Galanakis P, Bickel H, Gradinger R, Von Gumppenberg S, Förstl H | International journal of geriatric psychiatry | 2001 |
Acute Disease, Aged, Aged, 80 and over, Arthroplasty, Replacement, Hip, adverse effects, Confusion, epidemiology, Delirium, epidemiology, Female, Germany, epidemiology, Humans, Incidence, Male, Middle Aged, Odds Ratio, Prospective Studies, Risk Factors, Sampling Studies |
| Use of medications with anticholinergic effect predicts clinical severity of delirium symptoms in older medical inpatients. | Han L, McCusker J, Cole M, Abrahamowicz M, Primeau F, Elie M | Archives of internal medicine | 2001 |
Aged, Analysis of Variance, Cholinergic Antagonists, adverse effects, Dementia, complications, Disease Progression, Female, Hospitalization, Humans, Linear Models, Male, Risk Factors, Severity of Illness Index, Time Factors |
| Establishing a case-finding and referral system for at-risk older individuals in the emergency department setting: the SIGNET model. | Mion LC, Palmer RM, Anetzberger GJ, Meldon SW | Journal of the American Geriatrics Society | 2001 |
Aged, Case Management, organization & administration, Emergency Service, Hospital, Geriatric Assessment, Health Services for the Aged, organization & administration, Humans, Program Evaluation, Referral and Consultation, organization & administration, Risk Factors |
| Relationship between aggressive behaviors and depression among nursing home residents with dementia. | Menon AS, Gruber-Baldini AL, Hebel JR, Kaup B, Loreck D, Itkin Zimmerman S, Burton L, German P, Magaziner J | International journal of geriatric psychiatry | 2001 |
Aged, Aged, 80 and over, Aggression, Dementia, complications, Depression, epidemiology, Female, Homes for the Aged, Humans, Male, Maryland, epidemiology, Nursing Homes, Odds Ratio, Prevalence, Psychotic Disorders, complications, Risk, Severity of Illness Index, Verbal Behavior |
| Functional decline in independent elders after minor traumatic injury. | Shapiro MJ, Partridge RA, Jenouri I, Micalone M, Gifford D | Academic emergency medicine : official journal of the Society for Academic Emergency Medicine | 2001 |
Activities of Daily Living, Aged, Chi-Square Distribution, Comorbidity, Emergency Service, Hospital, statistics & numerical data, Female, Geriatric Assessment, Humans, Male, Prospective Studies, Sex Distribution, Wounds and Injuries, complications |
| The Hospital Elder Life Program: a model of care to prevent cognitive and functional decline in older hospitalized patients. Hospital Elder Life Program. | Inouye SK, Bogardus ST, Baker DI, Leo-Summers L, Cooney LM | Journal of the American Geriatrics Society | 2000 |
Activities of Daily Living, Aged, Cognition Disorders, diagnosis, Connecticut, Evidence-Based Medicine, Geriatric Assessment, Geriatric Nursing, organization & administration, Geriatrics, organization & administration, Health Services Research, Hospitals, Teaching, organization & administration, Humans, Job Description, Mass Screening, organization & administration, Mental Status Schedule, Models, Organizational, Outcome and Process Assessment (Health Care), Patient Admission, Patient Care Team, organization & administration, Program Evaluation, Quality Assurance, Health Care, organization & administration, Risk Factors |
| Prevention of delirium in hospitalized older patients: risk factors and targeted intervention strategies. | Inouye SK | Annals of medicine | 2000 |
Aged, Cognition Disorders, complications, Confidence Intervals, Controlled Clinical Trials as Topic, Critical Illness, Dehydration, complications, Delirium, etiology, Evidence-Based Medicine, Hospitalization, Humans, Iatrogenic Disease, Incidence, Intervention Studies, Nutrition Disorders, complications, Odds Ratio, Patient Admission, Polypharmacy, Restraint, Physical, Risk Factors, Urinary Catheterization, instrumentation, Vision Disorders, complications |
| Goals in geriatric assessment: are we measuring the right outcomes? | Bradley EH, Bogardus ST, van Doorn C, Williams CS, Cherlin E, Inouye SK | The Gerontologist | 2000 |
Activities of Daily Living, Aged, Caregivers, Case Management, Cross-Sectional Studies, Data Collection, Education, Female, Geriatric Assessment, Goals, Humans, Male, Marital Status, Mental Status Schedule, Outcome Assessment (Health Care), Patients, Physicians, Questionnaires |
| Serotonin and amino acids: partners in delirium pathophysiology? | van der Mast RC, Fekkes D | Seminars in clinical neuropsychiatry | 2000 |
Aged, Amino Acids, physiology, Blood-Brain Barrier, physiology, Brain, physiopathology, Delirium, etiology, Humans, Risk Factors, Serotonin, physiology |
| Is there a final common neural pathway in delirium? Focus on acetylcholine and dopamine. | Trzepacz PT | Seminars in clinical neuropsychiatry | 2000 |
Acetylcholine, physiology, Brain, physiopathology, Brain Mapping, Delirium, diagnosis, Dopamine, physiology, Humans, Synaptic Transmission, physiology |
| The mini-cog: a cognitive 'vital signs' measure for dementia screening in multi-lingual elderly. | Borson S, Scanlan J, Brush M, Vitaliano P, Dokmak A | International journal of geriatric psychiatry | 2000 |
Aged, Aged, 80 and over, Alzheimer Disease, diagnosis, Ethnic Groups, psychology, Female, Humans, Male, Mass Screening, Mental Recall, Mental Status Schedule, statistics & numerical data, Middle Aged, Multilingualism, Neuropsychological Tests, statistics & numerical data, Psychometrics, Psychomotor Performance, Reproducibility of Results, United States |
| The Clinician Assessment of Fluctuation and the One Day Fluctuation Assessment Scale. Two methods to assess fluctuating confusion in dementia. | Walker MP, Ayre GA, Cummings JL, Wesnes K, McKeith IG, O'Brien JT, Ballard CG | The British journal of psychiatry : the journal of mental science | 2000 |
Aged, Clinical Protocols, Confusion, diagnosis, Dementia, diagnosis, Diagnosis, Differential, Electroencephalography, methods, England, epidemiology, Female, Humans, Male, Psychiatric Status Rating Scales, Research Design |
| Delirium on hospital admission in aged hip fracture patients: prediction of mortality and 2-year functional outcomes. | Dolan MM, Hawkes WG, Zimmerman SI, Morrison RS, Gruber-Baldini AL, Hebel JR, Magaziner J | The journals of gerontology. Series A, Biological sciences and medical sciences | 2000 |
Activities of Daily Living, Affect, physiology, Age Factors, Aged, Aged, 80 and over, Cognition, physiology, Confounding Factors (Epidemiology), Continental Population Groups, Delirium, etiology, Depression, etiology, Disease, Female, Follow-Up Studies, Forecasting, Hip Fractures, complications, Hospitalization, Humans, Length of Stay, Long-Term Care, Male, Pain, psychology, Patient Admission, Patient Discharge, Prognosis, Recovery of Function, physiology, Risk Factors, Sex Factors, Statistics as Topic, Survival Rate |
| Acute confusional states in patients undergoing hip surgery. a prospective observation study. | Duppils GS, Wikblad K | Gerontology | 2000 |
Acute Disease, Aged, Aged, 80 and over, Aging, psychology, Arthroplasty, Replacement, Hip, Cognition Disorders, complications, Confusion, epidemiology, Female, Hip Fractures, surgery, Hospitalization, Humans, Incidence, Male, Prospective Studies, Social Isolation |
| Delirium is independently associated with poor functional recovery after hip fracture. | Marcantonio ER, Flacker JM, Michaels M, Resnick NM | Journal of the American Geriatrics Society | 2000 |
Activities of Daily Living, Aged, Aged, 80 and over, Cognition Disorders, complications, Delirium, etiology, Female, Hip Fractures, complications, Humans, Length of Stay, Male, Prognosis, Prospective Studies, Risk Factors, United States, epidemiology, Walking |
| Development of delirium: a prospective cohort study in a community hospital. | Martin NJ, Stones MJ, Young JE, Bédard M | International psychogeriatrics / IPA | 2000 |
Aged, Cohort Studies, Delirium, diagnosis, Disease Progression, Female, Hospitals, Community, Humans, Male, Patient Admission, Prospective Studies, Psychological Tests, Risk Factors, Sensitivity and Specificity |
| Do hospital fall prevention programs work? A systematic review. | Oliver D, Hopper A, Seed P | Journal of the American Geriatrics Society | 2000 |
Accidental Falls, prevention & control, Confidence Intervals, Health Services Research, Hospital Administration, Humans, Program Evaluation, Prospective Studies, Randomized Controlled Trials as Topic, Regression Analysis, Research Design, Risk Assessment, Risk Factors, Risk Management, organization & administration, Safety Management, organization & administration |
| An epidemiological study of falls on integrated general medical wards. | Vassallo M, Azeem T, Pirwani MF, Sharma JC, Allen SC | International journal of clinical practice | 2000 |
Accidental Falls, prevention & control, Aged, Female, Hospitalization, statistics & numerical data, Humans, Male, Middle Aged, Patients’ Rooms, statistics & numerical data, Prospective Studies, Risk Factors |
| Falls on integrated medical wards. | Vassallo M, Amersey RA, Sharma JC, Allen SC | Gerontology | 2000 |
Accidental Falls, statistics & numerical data, Age Distribution, Aged, Aged, 80 and over, Data Collection, Female, Great Britain, epidemiology, Hospital Departments, statistics & numerical data, Humans, Incidence, Male, Probability, Prospective Studies, Risk Factors, Sex Distribution, Wounds and Injuries, epidemiology |
| Survival in end-stage dementia following acute illness. | Morrison RS, Siu AL | JAMA : the journal of the American Medical Association | 2000 |
Acute Disease, Advance Directives, Aged, Aged, 80 and over, Cognition, Cost of Illness, Dementia, complications, Female, Hip Fractures, complications, Hospitalization, Humans, Male, Palliative Care, Patient Care, Pneumonia, complications, Prognosis, Proportional Hazards Models, Prospective Studies, Survival Analysis |
| Delirium in terminal cancer: a prospective study using daily screening, early diagnosis, and continuous monitoring. | Gagnon P, Allard P, Mâsse B, DeSerres M | Journal of pain and symptom management | 2000 |
Aged, Canada, Critical Illness, psychology, Delirium, epidemiology, Female, Humans, Incidence, Male, Neoplasms, psychology, Prospective Studies |
| Impact of delirium on the short term prognosis of advanced cancer patients. Italian Multicenter Study Group on Palliative Care. | Caraceni A, Nanni O, Maltoni M, Piva L, Indelli M, Arnoldi E, Monti M, Montanari L, Amadori D, De Conno F | Cancer | 2000 |
Adolescent, Adult, Aged, Delirium, etiology, Female, Humans, Male, Middle Aged, Multicenter Studies as Topic, Neoplasms, diagnosis, Palliative Care, Prognosis, Prospective Studies, Survival Analysis |
| Outcomes associated with delirium in acutely hospitalized acquired immune deficiency syndrome patients. | Uldall KK, Harris VL, Lalonde B | Comprehensive psychiatry | 2000 |
Acquired Immunodeficiency Syndrome, complications, Adult, Delirium, etiology, Female, HIV Infections, complications, Humans, Length of Stay, Male, Prognosis, Prospective Studies, Treatment Outcome, United States, epidemiology |
| Association between delirium and death in AIDS patients. | Uldall KK, Ryan R, Berghuis JP, Harris VL | AIDS patient care and STDs | 2000 |
Acquired Immunodeficiency Syndrome, complications, Adult, Delirium, complications, Female, Humans, Length of Stay, Male, Medical Records, Middle Aged, Retrospective Studies, Severity of Illness Index, Survival Analysis, Washington, epidemiology |
| Temporal association between hospitalization and rate of falls after discharge. | Mahoney JE, Palta M, Johnson J, Jalaluddin M, Gray S, Park S, Sager M | Archives of internal medicine | 2000 |
Accidental Falls, statistics & numerical data, Activities of Daily Living, classification, Acute Disease, Aged, Aged, 80 and over, Female, Geriatric Assessment, statistics & numerical data, Hospitalization, statistics & numerical data, Humans, Male, Patient Discharge, statistics & numerical data, Risk Factors, Time Factors, Wisconsin, epidemiology, Wounds and Injuries, epidemiology |
| Consequences of not recognizing delirium superimposed on dementia in hospitalized elderly individuals. | Fick D, Foreman M | Journal of gerontological nursing | 2000 |
Activities of Daily Living, Aged, Aged, 80 and over, Comorbidity, Delirium, complications, Dementia, complications, Female, Geriatric Assessment, Geriatric Nursing, methods, Hospitalization, Humans, Incidence, Male, Mental Status Schedule, Nursing Assessment, methods, Prevalence |
| An evidence-based clinical approach to the diagnosis of dementia. | Chong MS, Sahadevan S | Annals of the Academy of Medicine, Singapore | 2003 |
Alzheimer Disease, diagnosis, Brain, pathology, Caregivers, Delirium, diagnosis, Dementia, diagnosis, Dementia, Vascular, diagnosis, Evidence-Based Medicine, Health Status Indicators, Humans, Magnetic Resonance Imaging, Neuropsychological Tests, Tomography, X-Ray Computed |
| The prognostic significance of subsyndromal delirium in elderly medical inpatients. | Cole M, McCusker J, Dendukuri N, Han L | Journal of the American Geriatrics Society | 2003 |
Aged, Aged, 80 and over, Cohort Studies, Cost of Illness, Delirium, diagnosis, Female, Health Status, Humans, Length of Stay, Male, Prognosis |
| An empirical study of different diagnostic criteria for delirium among elderly medical inpatients. | Cole MG, Dendukuri N, McCusker J, Han L | The Journal of neuropsychiatry and clinical neurosciences | 2003 |
Aged, Aged, 80 and over, Confusion, epidemiology, Delirium, diagnosis, Dementia, diagnosis, Diagnosis, Differential, Diagnostic and Statistical Manual of Mental Disorders, Empirical Research, Female, Geriatric Assessment, Humans, Inpatients, International Classification of Diseases, standards, Male, Prospective Studies, Psychiatric Status Rating Scales, standards, Randomized Controlled Trials as Topic, statistics & numerical data, Reproducibility of Results, Sensitivity and Specificity |
| Delirium in the course of cancer treatment. | Fann JR, Sullivan AK | Seminars in clinical neuropsychiatry | 2003 |
Analgesics, Opioid, adverse effects, Delirium, diagnosis, Hematopoietic Stem Cell Transplantation, adverse effects, Humans, Immunotherapy, adverse effects, Neoplasms, complications, Pain, drug therapy, Risk Factors, Terminal Care |
| A model for managing delirious older inpatients. | Flaherty JH, Tariq SH, Raghavan S, Bakshi S, Moinuddin A, Morley JE | Journal of the American Geriatrics Society | 2003 |
Aged, Aged, 80 and over, Delirium, economics, Geriatric Nursing, economics, Health Facility Environment, economics, Hospital Units, economics, Humans, Intensive Care, economics, Mental Health Services, economics, Models, Nursing, Models, Organizational, Program Development, economics |
| Donepezil for postoperative delirium. | Gleason OC | Psychosomatics | 2003 |
Aged, Arthroplasty, Replacement, Hip, Delirium, diagnosis, Female, Hip Fractures, surgery, Humans, Indans, therapeutic use, Mental Status Schedule, Nootropic Agents, therapeutic use, Piperidines, therapeutic use, Postoperative Complications, diagnosis, Treatment Outcome |
| Cognitive impairment in hip fracture patients: timing of detection and longitudinal follow-up. | Gruber-Baldini AL, Zimmerman S, Morrison RS, Grattan LM, Hebel JR, Dolan MM, Hawkes W, Magaziner J | Journal of the American Geriatrics Society | 2003 |
Activities of Daily Living, Age Factors, Aged, Aged, 80 and over, Cognition Disorders, complications, Cohort Studies, Delirium, complications, Dementia, complications, Female, Follow-Up Studies, Hip Fractures, complications, Hospitalization, Humans, Incidence, Longitudinal Studies, Male, Prevalence, Psychiatric Status Rating Scales, Regression Analysis, Sex Factors, Time Factors |
| Delirium in older emergency department patients discharged home: effect on survival. | Kakuma R, du Fort GG, Arsenault L, Perrault A, Platt RW, Monette J, Moride Y, Wolfson C | Journal of the American Geriatrics Society | 2003 |
Aged, Aged, 80 and over, Comorbidity, Delirium, complications, Emergency Service, Hospital, statistics & numerical data, Female, Humans, Male, Mortality, Patient Discharge, Prognosis, Prospective Studies, Quebec |
| Delirium among newly admitted postacute facility patients: prevalence, symptoms, and severity. | Kiely DK, Bergmann MA, Murphy KM, Jones RN, Orav EJ, Marcantonio ER | The journals of gerontology. Series A, Biological sciences and medical sciences | 2003 |
Aged, Aged, 80 and over, Boston, epidemiology, Delirium, diagnosis, Female, Humans, Male, Prevalence, Skilled Nursing Facilities |
| Delirium in the critical care patient: what the professional staff needs to know. | Litton KA | Critical care nursing quarterly | 2003 |
Aged, Alcohol Withdrawal Delirium, etiology, Anxiety, etiology, Comorbidity, Confusion, etiology, Critical Care, Delirium, diagnosis, Education, Continuing, Humans, Nurse’s Role, Nursing Assessment, Psychotic Disorders, etiology, Risk Factors |
| Dementia after delirium in patients with femoral neck fractures. | Lundström M, Edlund A, Bucht G, Karlsson S, Gustafson Y | Journal of the American Geriatrics Society | 2003 |
Aged, Aged, 80 and over, Delirium, complications, Dementia, etiology, Female, Femoral Neck Fractures, complications, Follow-Up Studies, Humans, Male, Outcome Assessment (Health Care), Postoperative Period, Preoperative Care, Prospective Studies, Psychiatric Status Rating Scales, Risk Assessment, Time Factors |
| Delirium symptoms in post-acute care: prevalent, persistent, and associated with poor functional recovery. | Marcantonio ER, Simon SE, Bergmann MA, Jones RN, Murphy KM, Morris JN | Journal of the American Geriatrics Society | 2003 |
Activities of Daily Living, Aged, Aged, 80 and over, Delirium, complications, Female, Humans, Male, Prevalence, Prospective Studies, Recovery of Function, Skilled Nursing Facilities, United States, epidemiology |
| Delirium in the intensive care unit. | Marshall MC, Soucy MD | Critical care nursing quarterly | 2003 |
Aged, Anxiety, complications, Confusion, complications, Delirium, etiology, Dementia, complications, Humans, Intensive Care, Intensive Care Units, Mental Disorders, complications, Nursing Assessment, Psychomotor Agitation, complications, Risk Factors |
| Detecting acute confusion in older adults: Comparing clinical reasoning of nurses working in acute, long-term, and community health care environments. | McCarthy MC | Research in nursing & health | 2003 |
Acute Disease, Aged, Clinical Competence, Confusion, diagnosis, Delirium, diagnosis, Dementia, diagnosis, Diagnosis, Differential, Health Facility Environment, Home Care Services, Homes for the Aged, Hospitals, Humans, Nursing Assessment, Nursing Homes, Ohio, Qualitative Research |
| Delirium: elders tell their stories and guide nursing practice. | McCurren C, Cronin SN | Medsurg nursing : official journal of the Academy of Medical-Surgical Nurses | 2003 |
Aged, Aged, 80 and over, Delirium, nursing, Female, Humans, Life Change Events, Male, Nursing Assessment, Philosophy, Nursing, Questionnaires |
| Does delirium increase hospital stay? | McCusker J, Cole MG, Dendukuri N, Belzile E | Journal of the American Geriatrics Society | 2003 |
Aged, Aged, 80 and over, Cohort Studies, Delirium, diagnosis, Female, Geriatric Assessment, Humans, Length of Stay, statistics & numerical data, Linear Models, Male, Prospective Studies, Quebec, epidemiology, Severity of Illness Index |
| Delirium, depression, and anxiety. | Misra S, Ganzini L | Critical care clinics | 2003 |
Anxiety, diagnosis, Causality, Delirium, diagnosis, Depression, diagnosis, Humans, Incidence, Intensive Care, Prevalence, Risk Factors, Treatment Outcome |
| Impaired communication capacity and agitated delirium in the final week of terminally ill cancer patients: prevalence and identification of research focus. | Morita T, Tei Y, Inoue S | Journal of pain and symptom management | 2003 |
Aged, Communication, Critical Illness, psychology, Delirium, epidemiology, Female, Humans, Male, Middle Aged, Prevalence, Research, Retrospective Studies |
| Relationship between pain and opioid analgesics on the development of delirium following hip fracture. | Morrison RS, Magaziner J, Gilbert M, Koval KJ, McLaughlin MA, Orosz G, Strauss E, Siu AL | The journals of gerontology. Series A, Biological sciences and medical sciences | 2003 |
Aged, Aged, 80 and over, Analgesics, Opioid, administration & dosage, Cohort Studies, Confidence Intervals, Delirium, epidemiology, Dose-Response Relationship, Drug, Female, Follow-Up Studies, Hip Fractures, diagnosis, Humans, Incidence, Logistic Models, Male, Middle Aged, Multicenter Studies as Topic, Multivariate Analysis, New York City, Pain, diagnosis, Pain Measurement, Postoperative Period, Preoperative Care, Probability, Prospective Studies, Risk Assessment, Severity of Illness Index |
| Identification and management of delirium in the critically ill patient with cancer. | Morrison C | AACN clinical issues | 2003 |
Anti-Anxiety Agents, therapeutic use, Antipsychotic Agents, therapeutic use, Benzodiazepines, Delirium, diagnosis, Diagnosis, Differential, Humans, Mental Disorders, diagnosis, Neoplasms, complications, Risk Factors, Terminology as Topic |
| Delirium, depression often overlooked. | Naylor M | The American journal of nursing | 2003 |
Aged, Delirium, complications, Dementia, complications, Depression, complications, Hospitalization, Humans, Pilot Projects, United States |
| Donepezil for anticholinergic drug intoxication: a case report. | Noyan MA, Elbi H, Aksu H | Progress in neuro-psychopharmacology & biological psychiatry | 2003 |
Amitriptyline, adverse effects, Cholinergic Antagonists, adverse effects, Delirium, chemically induced, Drug Overdose, Humans, Indans, therapeutic use, Male, Middle Aged, Piperidines, therapeutic use |
| A patient with lithium intoxication developing at therapeutic serum lithium levels and persistent delirium after discontinuation of its administration. | Omata N, Murata T, Omori M, Wada Y | General hospital psychiatry | 2003 |
Antipsychotic Agents, adverse effects, Delirium, drug therapy, Drug Administration Schedule, Humans, Lithium Carbonate, adverse effects, Male, Middle Aged, Time Factors |
| Excited delirium: does it exist? | Paquette M | Perspectives in psychiatric care | 2003 |
Death, Sudden, Delirium, complications, Humans, Police, Psychomotor Agitation, complications, Restraint, Physical, Violence, prevention & control |
| A prospective, open-label, flexible-dose study of quetiapine in the treatment of delirium. | Sasaki Y, Matsuyama T, Inoue S, Sunami T, Inoue T, Denda K, Koyama T | The Journal of clinical psychiatry | 2003 |
Aged, Aged, 80 and over, Antipsychotic Agents, adverse effects, Delirium, drug therapy, Dibenzothiazepines, adverse effects, Dose-Response Relationship, Drug, Female, Humans, Male, Middle Aged, Treatment Outcome |
| The Delirium Observation Screening Scale: a screening instrument for delirium. | Schuurmans MJ, Shortridge-Baggett LM, Duursma SA | Research and theory for nursing practice | 2003 |
Activities of Daily Living, Aged, Aged, 80 and over, Case-Control Studies, Delirium, diagnosis, Female, Geriatric Assessment, Humans, Male, Mass Screening, methods, Mental Status Schedule, Nursing Assessment, methods, Nursing Evaluation Research, Observation, methods, Prospective Studies, Psychometrics, Questionnaires, Risk Factors, Sensitivity and Specificity |
| Delirium in adults with intellectual disabilities and DC-LD. | Simpson N | Journal of intellectual disability research : JIDR | 2003 |
Aged, Aged, 80 and over, Delirium, complications, Diagnostic and Statistical Manual of Mental Disorders, Female, Humans, Intellectual Disability, complications, Male |
| Do guidelines improve the process and outcomes of care in delirium? | Young LJ, George J | Age and ageing | 2003 |
Aged, Delirium, diagnosis, Education, Medical, Continuing, Education, Nursing, Continuing, England, Geriatric Assessment, Geriatrics, education, Hospitals, General, standards, Humans, Mental Status Schedule, Outcome and Process Assessment (Health Care), Patient Care Planning, Practice Guidelines as Topic, Scotland |
| Association between cardiac and noncardiac complications in patients undergoing noncardiac surgery: outcomes and effects on length of stay. | Fleischmann KE, Goldman L, Young B, Lee TH | The American journal of medicine | 2003 |
Aged, Female, Heart Diseases, epidemiology, Humans, Length of Stay, statistics & numerical data, Linear Models, Logistic Models, Male, Myocardial Infarction, epidemiology, Odds Ratio, Postoperative Complications, classification, Prospective Studies, Pulmonary Edema, epidemiology, Risk Factors |
| Risk for acute confusion in sensory-impaired, rural, long-term-care elders. | Cacchione PZ, Culp K, Dyck MJ, Laing J | Clinical nursing research | 2003 |
Acute Disease, Aged, psychology, Aged, 80 and over, Confusion, epidemiology, Female, Geriatric Assessment, Hearing Disorders, complications, Homes for the Aged, Humans, Iowa, epidemiology, Long-Term Care, psychology, Longitudinal Studies, Male, Mass Screening, Nursing Homes, Prevalence, Risk Factors, Rural Population, Vision Disorders, complications |
| Mortality and morbidity in nonagenarian patients following hip fracture surgery. | Formiga F, Lopez-Soto A, Sacanella E, Coscojuela A, Suso S, Pujol R | Gerontology | 2003 |
Aged, Aged, 80 and over, Female, Femoral Neck Fractures, mortality, Follow-Up Studies, Frail Elderly, Humans, Male, Pain, Postoperative, Prospective Studies, Walking, physiology |
| The last forty-eight hours of life in a Portuguese palliative care unit: does it differ from elsewhere? | Gonçalves JF, Alvarenga M, Silva A | Journal of palliative medicine | 2003 |
Drug Utilization Review, Female, Humans, Male, Medical Audit, Neoplasms, nursing, Palliative Care, standards, Portugal, Prospective Studies, Terminal Care, standards |
| Systemic infection, interleukin 1beta, and cognitive decline in Alzheimer's disease. | Holmes C, El-Okl M, Williams AL, Cunningham C, Wilcockson D, Perry VH | Journal of neurology, neurosurgery, and psychiatry | 2003 |
Aged, Aged, 80 and over, Alzheimer Disease, etiology, Central Nervous System Bacterial Infections, complications, Cognition Disorders, diagnosis, Female, Follow-Up Studies, Humans, Interleukin-1, blood, Male, Neuropsychological Tests |
| Postoperative confusion in schizophrenic patients is affected by interleukin-6. | Kudoh A, Takase H, Takahira Y, Katagai H, Takazawa T | Journal of clinical anesthesia | 2003 |
Abdomen, surgery, Adult, Aged, Analgesia, Epidural, Anesthesia, Epidural, Anesthesia, General, Confusion, blood, Humans, Hydrocortisone, blood, Interleukin-6, blood, Middle Aged, Postoperative Complications, blood, Schizophrenia, blood |
| Treating depression in Alzheimer disease: efficacy and safety of sertraline therapy, and the benefits of depression reduction: the DIADS. | Lyketsos CG, DelCampo L, Steinberg M, Miles Q, Steele CD, Munro C, Baker AS, Sheppard JM, Frangakis C, Brandt J, Rabins PV | Archives of general psychiatry | 2003 |
Activities of Daily Living, psychology, Aged, Alzheimer Disease, drug therapy, Ambulatory Care, Caregivers, psychology, Cognition Disorders, diagnosis, Comorbidity, Depressive Disorder, drug therapy, Drug Administration Schedule, Female, Geriatric Assessment, Humans, Male, Mental Disorders, diagnosis, Neuropsychological Tests, Placebos, Psychiatric Status Rating Scales, Serotonin Uptake Inhibitors, therapeutic use, Sertraline, therapeutic use, Single-Blind Method, Treatment Outcome |
| Six-month neuropsychological outcome of medical intensive care unit patients. | Jackson JC, Hart RP, Gordon SM, Shintani A, Truman B, May L, Ely EW | Critical care medicine | 2003 |
APACHE, Cognition Disorders, diagnosis, Depression, diagnosis, Female, Humans, Intensive Care Units, Length of Stay, Male, Middle Aged, Neuropsychological Tests, Prospective Studies, Quality of Life, Respiration, Artificial, adverse effects |
| Clinical practice guidelines for the sustained use of sedatives and analgesics in the critically ill adult. | Jacobi J, Fraser GL, Coursin DB, Riker RR, Fontaine D, Wittbrodt ET, Chalfin DB, Masica MF, Bjerke HS, Coplin WM, Crippen DW, Fuchs BD, Kelleher RM, Marik PE, Nasraway SA, Murray MJ, Peruzzi WT, Lumb PD, | Critical care medicine | 2002 |
Adult, Analgesia, standards, Analgesics, administration & dosage, Conscious Sedation, standards, Critical Care, standards, Delirium, Humans, Hypnotics and Sedatives, administration & dosage, Pain Measurement, standards, Sleep, drug effects |