NIDUS Delirium Bibliography

Delirium Bibliography books graphic What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!

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Title: Development of post-anesthesia care unit delirium is associated with differences in aperiodic and periodic alpha parameters of the EEG during emergence from general anesthesia - results from a prospective observational cohort study

Authors: Ostertag, J. Engelhard, A. Nuttall, R. Aydin, D. Schneider, G. García, P. S. Hinzmann, D. Sleigh, J. W. Kratzer, S. Kreuzer, M.

Year: 2023

Journal: Anesthesiology

Abstract: BACKGROUND: Intraoperative alpha-band power in frontal electrodes may provide helpful information about the balance of hypnosis and analgesia and has been associated with reduced occurrence of delirium in the post-anesthesia care unit (PACU). Recent studies suggest that narrow-band power computations from neural power spectra can benefit from separating periodic and aperiodic components of the EEG. This study investigates if such techniques are more useful in separating patients with and without delirium in the PACU at the group level as opposed to conventional power spectra. METHODS: Intraoperative EEG recordings of 32 patients who developed perioperative neurocognitive disorders (PACU-D) and 137 patients who did not (noPACU-D) were considered in this post-hoc secondary analysis. We calculated power spectra using conventional methods and applied the “fitting oscillations & one over f” (FOOOF) algorithm to separate aperiodic and periodic components to see if the EEG signature is different between groups. RESULTS: At the group level, noPACU-D and PACU-D patients presented with significantly higher alpha-band power and a broadband increase in power, allowing a “fair” separation based on conventional power spectra. Within the first third of emergence, the difference in median absolute alpha-band power amounted to 8.53dB (AUC:0.74[0.65;0.82]), reaching its highest value. In relative terms, the best separation was achieved in the second third of emergence with a difference in medians of 7.71% (AUC:0.70[0.61;0.79]). AUC values were generally lower towards the end of emergence with increasing arousal. CONCLUSIONS: Increased alpha-band power during emergence in noPACU-D patients can be traced back to an increase in oscillatory alpha activity and an overall increase in aperiodic broadband power. Although differences between PACU-D and noPACU-D patients can be detected relying on traditional methods, the separation of the signal allows a more detailed analysis. Together this may enable clinicians to detect patients at risk for PACU-D early in the emergence phase.

PMID: PMID

Keywords: PACU, delirium, EEG, hypnosis, alpha

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Total Records Found: 6753, showing 100 per page
Title	Authors	Journal	Year	Keywords
A Unique Presentation of Delirium in a Patient with Otherwise Asymptomatic COVID-19	Alkeridy, W. A. Almaghlouth, I. Alrashed, R. Alayed, K. Binkhamis, K. Alsharidi, A. Liu-Ambrose, T.	J Am Geriatr Soc	2020	Covid-19 atypical delirium fall outbreak
Postoperative delirium after abdominal aortic surgery: after ICU discharge surveillance should extend to the surgical ward	Alessandri, F. Bilotta, F.	Minerva Anestesiol	2020
The prevalence of emergence delirium and its associated factors among children at a postoperative unit: A retrospective cohort at a Middle Eastern hospital	Aldakhil, S. K. Salam, M. Albelali, A. A. Alkanhal, R. M. Alnemer, M. J. Alatassi, A.	Saudi J Anaesth	2020	Anesthesia Precedex Watcha Yale anxiety delirium surgery
Optimal goal of management of delirium in end-of-life cancer care	Akechi, T.	Lancet Oncol	2020
Multiple Peri-Operative Complications are Associated with Reduced Long Term Amputation Free Survival Following Revascularisation for Lower Limb Peripheral Artery Disease: A Population Based Linked Data Study	Aitken, S. J. Randall, D. A. Noguchi, N. Blyth, F. M. Naganathan, V.	Eur J Vasc Endovasc Surg	2020	Aged Aged, 80 and over Amputation Databases, Factual Female Humans Limb Salvage Lower Extremity/ blood supply Male Middle Aged New South Wales/epidemiology Peripheral Arterial Disease/diagnosis/mortality/ surgery Postoperative Complications/diagnosis/ epidemiology/mortality Progression-Free Survival Retrospective Studies Risk Assessment Risk Factors Time Factors Vascular Surgical Procedures/ adverse effects/mortality Data linkage Peripheral artery disease Post-operative complications Prognosis
Neurological manifestations and complications of COVID-19: A literature review	Ahmad, I. Rathore, F. A	J Clin Neurosci	2020	Clinical features Coronavirus Delirium Encephalitis Headache Neurology Stroke
The role of suvorexant in the prevention of delirium during acute hospitalization: A systematic review	Adams, A. D. Pepin, M. J. Brown, J. N.	J Crit Care	2020	Belsomra Confusion Critical care Critically ill Neurocognitive disorders Orexin receptor antagonist and the authors have no conflicts of interest to declare.
Quetiapine for delirium prophylaxis in high-risk critically ill patients	Abraham, M. P. Hinds, M. Tayidi, I. Jeffcoach, D. R. Corder, J. M. Hamilton, L. A. Lawson, C. M. Bollig, R. W. Heidel, R. E. Daley, B. J. Taylor, J. E. McMillen, J. C.	Surgeon	2020	Delirium Intensive care unit Quetiapine Surgery
Comparing outcomes after peripheral nerve block versus general anesthesia for lower extremity amputation: a nationwide exploratory retrospective cohort study in Japan	Abe, H. Sumitani, M. Matsui, H. Aso, S. Inoue, R. Fushimi, K. Uchida, K. Yasunaga, H. Yamada, Y.	Reg Anesth Pain Med	2020	lower extremity postoperative pain surgical outcome
Development of delirium: Association with old age, severe burns, and intensive care	Abdelrahman, I. Vieweg, R. Irschik, S. Steinvall, I. Sjöberg, F. Elmasry, M.	Burns	2020	Burns Delirium Inflammation Intensive care Old age Wound care procedures
Factors Associated With Postoperative Confusion and Prolonged Hospital Stay Following Deep Brain Stimulation Surgery for Parkinson Disease	Abboud, H. Genc, G. Saad, S. Thompson, N. Oravivattanakul, S. Alsallom, F. Yu, X. X. Floden, D. Gostkowski, M. Ahmed, A. Ezzeldin, A. Marouf, H. M. Mansour, O. Y. Fernandez, H. H.	Neurosurgery	2020	Dbs Deep-brain stimulation Hospital stay Parkinson disease Postoperative delirium Postoperative outcomes
Mortality and complications after emergency laparotomy in patients above 80 years	Aakre, E. K. Ulvik, A. Hufthammer, K. O. Jammer, I.	Acta Anaesthesiol Scand	2020	elderly frail surgery
Evaluation of an emergency department falls pathway for older people: A patient chart review	O' Keeffe A O' Grady S Cronin, F. Dolan, C. O' Hea A O' Shea KL Naughton, C.	Int Emerg Nurs	2020
Rapid in-person cognitive screening in the preoperative setting: Test considerations and recommendations from the Society for Perioperative Assessment and Quality Improvement (SPAQI)	Arias, F. Wiggins, M. Urman, R. D. Armstrong, R. Pfeifer, K. Bader, A. M. Libon, D. J. Chopra, A. Price, C. C.	Journal of Clinical Anesthesia	2020	anesthesiology attention clock drawing test cognition cognitive defect dementia geriatrics human language memory methodology Mini Mental State Examination neuropsychology peer review perioperative monitoring primary medical care priority journal psychometry review sensitivity and specificity telephone interview total quality management workflow
Updated nomenclature of delirium and acute encephalopathy: statement of ten Societies	Slooter, A. J. C. Otte, W. M. Devlin, J. W. Arora, R. C. Bleck, T. P. Claassen, J. Duprey, M. S. Ely, E. W. Kaplan, P. W. Latronico, N. Morandi, A. Neufeld, K. J. Sharshar, T. MacLullich, A. M. J. Stevens, R. D.	Intensive Care Medicine	2020	acute brain disease article delirium human nomenclature organization
Nonsedation or Light Sedation in Critically Ill, Mechanically Ventilated Patients	Olsen, H. T. Nedergaard, H. K. Strøm, T. Oxlund, J. Wian, K. A. Ytrebø, L. M. Kroken, B. A. Chew, M. Korkmaz, S. Lauridsen, J. T. Toft, P.	The New England journal of medicine	2020	NCT01967680 acute kidney failure adult agitation APACHE article artificial ventilation coma controlled study critically ill patient delirium female human intensive care unit major clinical study male medical research mortality multicenter study outcome assessment randomization randomized controlled trial sedation thromboembolism ventilated patient
Ketamine Safety and Use in the Emergency Department for Pain and Agitation/Delirium: A Health System Experience	Mo, H. Campbell, M. J. Fertel, B. S. Lam, S. W. Wells, E. J. Casserly, E. Meldon, S. W.	The western journal of emergency medicine	2020	adult adverse drug reaction agitation analgesia article clinical evaluation comorbidity delirium dissociation drug safety drug therapy emergency ward endotracheal intubation female human incidence major clinical study male medical record review nasal cannula non rebreathing valve patient information pharmacokinetics retrospective study sedation side effect ketamine
Impact of skeletal muscle mass on postoperative delirium in patients undergoing free flap repair after oral cancer resection	Makiguchi, T. Yamaguchi, T. Nakamura, H. Ogawa, M. Harimoto, N. Shirabe, K. Yokoo, S.	Journal of plastic surgery and hand surgery	2020	adult article cancer patient cancer surgery controlled study diet therapy exercise female free tissue graft human insomnia major clinical study male mouth cancer muscle mass positron emission tomography-computed tomography postoperative delirium preoperative evaluation prevention risk assessment risk factor sarcopenia skeletal muscle surgery third lumbar vertebra albumin endogenous compound
Identifying delirium in Parkinson disease: A pilot study	Lawson, R. A. Richardson, S. J. Yarnall, A. J. Burn, D. J. Allan, L. M.	International Journal of Geriatric Psychiatry	2020	aged article clinical article consensus controlled study delirium DSM-5 female frailty hospital patient hospitalization human incidence male Parkinson disease pilot study prevalence vignette
Presurgical cognitive impairment is associated with postoperative delirium and postoperative cognitive dysfunction	Knaak, C. Brockhaus, W. R. Spies, C. Borchers, F. Piper, S. K. Radtke, F. M. Lachmann, G.	Minerva anestesiologica	2020	aged anesthesia article controlled study Diagnostic and Statistical Manual of Mental Disorders female follow up human major clinical study male postoperative cognitive dysfunction postoperative delirium randomization randomized controlled trial
The effects of elective aortic repair, colorectal cancer surgery and subsequent postoperative delirium on long-term quality of life, cognitive functioning and depressive symptoms in older patients	Janssen, T. L. de Vries, J. Lodder, P. Faes, M. C. Ho, G. H. Gobardhan, P. D. van der Laan, L.	Aging & mental health	2020	abdominal aortic aneurysm abdominal surgery adult aortic reconstruction article cancer patient cancer surgery cognition cohort analysis colorectal cancer controlled study depression elective surgery female human major clinical study male Mini Mental State Examination outcome assessment postoperative delirium postoperative period prospective study psychological well-being quality of life questionnaire risk factor surgery surgical patient World Health Organization
American Society for Enhanced Recovery and Perioperative Quality Initiative Joint Consensus Statement on Postoperative Delirium Prevention	Hughes, C. G. Boncyk, C. S. Culley, D. J. Fleisher, L. A. Leung, J. M. McDonagh, D. L. Gan, T. J. McEvoy, M. D. Miller, T. E.	Anesthesia and analgesia	2020	adult adverse outcome article cognitive defect complication Delphi study high risk population hospital readmission human institutionalization length of stay major surgery outcome assessment physician postoperative delirium prevention skill
Healthcare professionals' reports of cancer pain cues among older people with delirium: a qualitative-quantitative content analysis	Graham, C. A. Chaves, G. Harrison, R. Gauthier, L. R. Nissim, R. Zimmermann, C. Chan, V. Rodin, G. Stevens, B. Gagliese, L.	Journal of pain and symptom management	2020	adult article bivariate analysis cancer pain content analysis controlled study data analysis software delirium demography doctor nurse relation female genetic transcription human informed consent interview major clinical study male pain assessment quantitative analysis self report
Preoperative Cognitive Abnormality, Intraoperative Electroencephalogram Suppression, and Postoperative Delirium: A Mediation Analysis	Fritz, B. A. King, C. R. Ben Abdallah, A. Lin, N. Mickle, A. M. Budelier, T. P. Oberhaus, J. Park, D. Maybrier, H. R. Wildes, T. S. Avidan, M. S. Apakama, G. Aranake-Chrisinger, A. Bolzenius, J. Burton, J. Cui, V. Emmert, D. A. Goswami, S. Graetz, T. J. G	Anesthesiology	2020	adult aging article complication convalescence effect size electroencephalogram electroencephalography female general anesthesia human incidence interview major clinical study male medical record review mentally disabled person postoperative delirium preoperative evaluation randomization randomized controlled trial secondary analysis surgery university hospital
Delirium screening and mortality in patients with dementia admitted to acute hospitals	Codling, D. Hood, C. Bassett, P. Smithard, D. Crawford, M. J.	Aging & mental health	2020	aged article cognitive defect controlled study England female human major clinical study male mortality multicenter study secondary analysis very elderly Wales
Do Neuroleptics Still Have a Role in Patients With Delirium?	Nikooie, R. Oh, E. S. Zhang, A. Robinson, K. A. Needham, D. M.	Annals of internal medicine	2020	adult article delirium human neuroleptic agent
Randomized clinical trial of intraoperative dexmedetomidine to prevent delirium in the elderly undergoing major non-cardiac surgery	Li, C. J. Wang, B. J. Mu, D. L. Hu, J. Guo, C. Li, X. Y. Ma, D. Wang, D. X.	British Journal of Surgery	2020	ChiCTRIPR15007654 injection device Slgo cisatracurium dexamethasone dexmedetomidine flurbiprofen axetil methylprednisolone midazolam morphine parecoxib propofol sufentanil adult aged all cause mortality article Barthel index bradycardia Child Pugh score confusion assessment method controlled study delirium double blind procedure drug infusion drug safety extubation female follow up human hypertension hypotension incidence loading drug dose major clinical study male mental disease assessment middle aged Mini Mental State Examination nausea and vomiting numeric rating scale observational study perioperative period priority journal randomized controlled trial risk factor
Risk factors for adverse drug reactions in older inpatients of geriatric wards at admission: Multicenter study	Kojima, T. Matsui, T. Suzuki, Y. Takeya, Y. Tomita, N. Kozaki, K. Kuzuya, M. Rakugi, H. Arai, H. Akishita, M.	Geriatrics and Gerontology International	2020	albumin creatinine adverse drug reaction aged albumin blood level article bleeding cohort analysis creatinine blood level dehydration delirium disease association dizziness edema electrolyte disturbance endocrine disease female functional status gastrointestinal disease geriatric assessment geriatric hospital heart arrhythmia heart failure hematologic disease hospital admission human hyperglycemia hypoglycemia Japan kidney failure length of stay liver disease major clinical study male medical record multicenter study neurologic disease observational study priority journal rash respiratory failure retrospective study risk assessment risk factor sedation symptom very elderly
Real-world effectiveness of ramelteon and suvorexant for delirium prevention in 948 patients with delirium risk factors	Hatta, K. Kishi, Y. Wada, K. Takeuchi, T. Hashimoto, N. Suda, K. Taira, T. Tsuchida, K. Ohmori, T. Akizuki, N. Nishio, Y. Nakanishi, Y. Usui, C. Kurata, A. Horikawa, N. Eguchi, H. Ito, S. Muto, H. Nakamura, H. Uchimura, N.	Journal of Clinical Psychiatry	2020	corticosteroid derivative opiate derivative ramelteon suvorexant acute disease aged article clinical outcome clinical practice consultation delirium drug effect drug efficacy DSM-5 elective surgery female hospitalization human incidence insomnia major clinical study male mental health service multicenter study observational study outcome assessment patient decision making physiatrist prescription priority journal prospective study risk assessment risk factor somnolence
Independent Association Between Type of Intraoperative Blood Transfusion and Postoperative Delirium After Complex Spinal Fusion for Adult Deformity Correction	Elsamadicy, A. A. Adil, S. M. Charalambous, L. Drysdale, N. Koo, A. B. Lee, M. Kundishora, A. J. Camara-Quintana, J. Kolb, L. Laurans, M. Abbed, K. Karikari, I. O.	Spine	2020	adult age article bleeding blood transfusion cohort analysis comorbidity complication controlled study female health care cost hospitalization human incidence major clinical study male medical record outcome assessment patient care postoperative delirium retrospective study spine fusion spine malformation surgery
Practices related to assessment of sedation, analgesia and delirium among critical care pediatricians in Brazil	Colleti Junior, J. Araujo, O. R. Andrade, A. B. Carvalho, W. B.	Einstein (Sao Paulo, Brazil)	2020	analgesia article Brazil child delirium demography e-mail human patient comfort pediatric intensive care unit pediatrician questionnaire Ramsay Sedation Scale sedation
Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study	Chen, N. Zhou, M. Dong, X. Qu, J. Gong, F. Han, Y. Qiu, Y. Wang, J. Liu, Y. Wei, Y. Xia, J. Yu, T. Zhang, X. Zhang, L.	The Lancet	2020	adult age article China chronic disease clinical feature confusion Coronavirus disease 2019 Coronavirus infection coughing descriptive research disease exacerbation dyspnea epidemiological data exposure female fever follow up headache human major clinical study male marketing medical history multiple organ failure myalgia nausea and vomiting pneumothorax priority journal real time polymerase chain reaction respiratory distress retrospective study sea food sore throat thorax pain virus detection virus pneumonia
Association between postoperative delirium and mortality in elderly patients undergoing hip fractures surgery: a meta-analysis	Bai, J. Liang, Y. Zhang, P. Liang, X. He, J. Wang, J. Wang, Y.	Osteoporosis International	2020	article disease association DSM-III DSM-IV follow up hip fracture hip surgery hospital mortality human incidence perioperative period postoperative delirium postoperative period prevalence priority journal scoring system surgical mortality surgical risk systematic review
Impact of frailty on short-term outcomes in patients undergoing transsphenoidal pituitary surgery	Asemota, A. O. Gallia, G. L.	Journal of Neurosurgery	2020	acute heart infarction acute kidney failure adult aged article Black person brain hematoma brain hemorrhage brain infarction cerebrospinal fluid rhinorrhea Charlson Comorbidity Index cohort analysis comorbidity consciousness disorder deep vein thrombosis delirium diabetes insipidus diplopia epistaxis female frailty Hispanic human hypernatremia hyperosmolality hypertension hyponatremia hypoosmolality hypophysis tumor iatrogenic disease inappropriate vasopressin secretion length of stay lowest income group lung embolism lung insufficiency major clinical study male medicaid medicare meningitis mental health middle aged mortality rate ophthalmoplegia postoperative nausea and vomiting priority journal reoperation strabismus transsphenoidal hypophysectomy treatment outcome visual field defect
Randomised controlled trial to investigate the relationship between mild hypercapnia and cerebral oxygen saturation in patients undergoing major surgery	Wong, C. Churilov, L. Cowie, D. Tan, C. O. Hu, R. Tremewen, D. Pearce, B. Pillai, P. Karalapillai, D. Bellomo, R. Weinberg, L.	BMJ Open	2020	delirium hypercapnia oximetry respiration, artificial spectroscopy, near infrared
Establishment and validation of a delirium prediction model for neurosurgery patients in intensive care	Wang, J. Ji, Y. Wang, N. Chen, W. Bao, Y. Qin, Q. Ma, C. Xiao, Q. Li, S.	Int J Nurs Pract	2020	delirium neurosurgery nursing prediction model risk factors
Early mobilisation after transfemoral transcatheter aortic valve implantation: results of the MobiTAVI trial	Vendrik, J. Vlastra, W. van Mourik, M. S. Delewi, R. Beijk, M. A. Lemkes, J. Wykrzykowska, J. J. de Winter, R. J. Henriques, J. S. Piek, J. J. Vis, M. M. Koch, K. T. Baan, J., Jr.	Neth Heart J	2020	Ambulation Early mobilisation Percutaneous valve Safety protocol Transfemoral transcatheter aortic valve implantation Vascular complications
Influence of sedation on delirium recognition in critically ill patients: A multinational cohort study	van den Boogaard, M. Wassenaar, A. van Haren, F. M. P. Slooter, A. J. C. Jorens, P. G. van der Jagt, M. Simons, K. S. Egerod, I. Burry, L. D. Beishuizen, A. Pickkers, P. Devlin, J. W.	Aust Crit Care	2020	Assessment Cam-icu Delirium Icdsc Intensive care Sedation NCT02518646 adult article checklist clinical evaluation cohort analysis controlled study critically ill patient female human intensive care psychosis intensive care unit major clinical study male multicenter study nurse prospective study Richmond Agitation Sedation Scale secondary analysis
Intraoperative reduction of vasopressors using processed electroencephalographic monitoring in patients undergoing elective cardiac surgery: a randomized clinical trial	Sponholz, C. Schuwirth, C. Koenig, L. Hoyer, H. Coldewey, S. M. Schelenz, C. Doenst, T. Kortgen, A. Bauer, M.	J Clin Monit Comput	2020	Adverse events Cardiac anesthesia Catecholamines Neuromonitoring
Enhanced rehabilitation and care models for adults with dementia following hip fracture surgery	Smith, T. O. Gilbert, A. W. Sreekanta, A. Sahota, O. Griffin, X. L. Cross, J. L. Fox, C. Lamb, S. E.	Cochrane Database Syst Rev	2020
Prospective Evaluation of Delirium in Geriatric Patients Undergoing Emergency General Surgery	Saljuqi, A. T. Hanna, K. Asmar, S. Tang, A. Zeeshan, M. Gries, L. Ditillo, M. Kulvatunyou, N. Castanon, L. Joseph, B.	J Am Coll Surg	2020
Predisposing and Precipitating Factors Associated With Postoperative Delirium in Patients Undergoing Cardiac Surgery at a Veterans Affairs Medical Center: A Pilot Retrospective Analysis	Russell, M. D. Pinkerton, C. Sherman, K. A. Ebert, T. J. Pagel, P. S.	J Cardiothorac Vasc Anesth	2020	Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition cardiac surgery complications cardiopulmonary bypass delirium geriatrics
Dopaminergic Hyperactivity in Neurological Patients with Delirium	Ramirez-Bermudez, J. Perez-Neri, I. Montes, S. Nente, F. Ramirez-Abascal, M. Carrillo-Mezo, R. Perez-Esparza, R. Soto-Hernandez, J. L. Espinola-Nadurille, M. Bayliss, L. De Jesus Flores Rivera, J. Rios, C.	Arch Med Res	2020	Autoimmune limbic encephalitis Confusional state Delirium Dopamine Homovanillic acid Neuropsychiatry
Effects of intravenous and mask induction on post-operative emergence delirium in pediatric patients undergoing tonsillectomy with or without adenoidectomy	Peker, K. Polat, R.	Ir J Med Sci	2020	Intravenous induction Mask induction Pediatric emergence delirium adenoidectomy anesthesia induction article cannula child controlled study emergence agitation female human incidence leg major clinical study male operating room pediatric anesthesia pediatric patient postoperative pain preschool child prospective study randomized controlled trial recovery room remission single blind procedure surgery tonsillectomy university hospital vascular access nitrous oxide oxygen sevoflurane
Safety and Tolerability of Rapid Administration Undiluted Levetiracetam	Morgan, O. Medenwald, B.	Neurocrit Care	2020	Anticonvulsants Humans Intravenous
New use of psychotropic medication after hospitalization among people with dementia	Mollers, T. Perna, L. Stocker, H. Ihle, P. Schubert, I. Schottker, B. Frolich, L. Brenner, H.	Int J Geriatr Psychiatry	2020	claims data dementia hospitalization psychotropic medication
A logistic regression analysis comparing minimalistic approach and intubation anaesthesia in patients undergoing transfemoral transcatheter aortic valve replacement	Maier, A. Hammerich, B. Humburger, F. Brieschal, T. Heidt, T. Bothe, W. Schrofel, H. Kaier, K. Zehender, M. Reinohl, J. Bode, C. von Zur Muhlen, C. Stachon, P.	PLoS One	2020
Anticipating Postoperative Delirium During Burst Suppression Using Electroencephalography	Ma, O. Crepeau, A. Z. Dutta, A. Bliss, D.	IEEE Trans Biomed Eng	2020	adult article brain injury clinical article complication cooling electroencephalography female heart arrest heart surgery human hypothermia incidence male postoperative delirium prognosis reperfusion surgery surgical technique warming
Can haloperidol prophylaxis reduce the incidence of delirium in critically ill patients in intensive care units? A systematic review and meta-analysis	Lin, P. Zhang, J. Shi, F. Liang, Z. A.	Heart Lung	2020	Delirium Haloperidol Intensive care Meta-analysis Randomized clinical trial
Benzodiazepines for treatment of patients with delirium excluding those who are cared for in an intensive care unit	Li, Y. Ma, J. Jin, Y. Li, N. Zheng, R. Mu, W. Wang, J. Si, J. H. Chen, J. Shang, H. C.	Cochrane Database Syst Rev	2020
Delirium prevalence and prevention in patients with acute brain injury: A prospective before-and-after intervention study	Larsen, L. K. Moller, K. Petersen, M. Egerod, I.	Intensive Crit Care Nurs	2020	Brain injuries Critical care Critical care nursing Delirium Intensive care units Neuroscience nursing Prevention
Postoperative anaemia might be a risk factor for postoperative delirium and prolonged hospital stay: A secondary analysis of a prospective cohort study	Kunz, J. V. Spies, C. D. Bichmann, A. Sieg, M. Mueller, A.	PLoS One	2020
Development of a Simple and Practical Delirium Screening Tool for Use in Surgical Wards	Kubota, K. Suzuki, A. Ohde, S. Yamada, U. Fujitani, I. Koitabashi, A.	J Nurs Res	2020	adult area under the curve article bootstrapping controlled study delirium diagnostic accuracy diagnostic test accuracy study disorientation female hallucination hospital patient human major clinical study male medical record nurse receiver operating characteristic restlessness retrospective study sensitivity and specificity somnolence surgical ward
Psychometric evaluation of the family caregiver ICU delirium knowledge questionnaire	Krewulak, K. D. Bull, M. J. Ely, E. W. Stelfox, H. T. Fiest, K. M.	BMC Health Serv Res	2020	Critical care Delirium prevention and management Family caregivers Intensive care unit adult article caregiver content validity controlled study critically ill patient Cronbach alpha coefficient cross-sectional study delirium face validity female human intensive care unit internal consistency major clinical study male multidisciplinary team nurse path analysis questionnaire risk factor
The Impact of Acute Kidney Injury in the Perioperative Period on the Incidence of Postoperative Delirium in Patients Undergoing Coronary Artery Bypass Grafting-Observational Cohort Study	Kotfis, K. Slozowska, J. Listewnik, M. Szylinska, A. Rotter, I.	Int J Environ Res Public Health	2020	Aki Cabg Gfr Kdigo Pod acute kidney injury creatinine delirium glomerular filtration rate
Delirium point prevalence studies in inpatient settings: A systematic review and meta-analysis	Koirala, B. Hansen, B. R. Hosie, A. Budhathoki, C. Seal, S. Beaman, A. Davidson, P. M.	J Clin Nurs	2020	delirium inpatient meta-analysis point prevalence systematic review adult benchmarking dementia female high risk patient hospital patient human male patient care prevalence quality improvement study review risk assessment sample siz
Validity and Reliability of the Memorial Delirium Assessment Scale-Thai Version (MDAS-T) for Assessment of Delirium in Palliative Care Patients	Klankluang, W. Pukrittayakamee, P. Atsariyasing, W. Siriussawakul, A. Chanthong, P. Tongsai, S. Tayjasanant, S.	Oncologist	2020	Delirium Mdas Palliative care Screening Sensitivity and specificity Validity and reliability adult article construct validity content validity controlled study correlation coefficient Cronbach alpha coefficient distress syndrome DSM-5 exploratory factor analysis female gold standard human intensive care unit internal consistency interrater reliability major clinical study male palliative therapy principal component analysis receiver operating characteristic sensitivity and specificity
The Impact of an Attending Intensivist on the Clinical Outcomes of Patients Admitted to the Cardiac Surgical Intensive Care Unit after Coronary Artery Bypass Grafting	Kim, D. J. Sohn, B. Kim, H. Chang, H. W. Lee, J. H. Kim, J. S. Lim, C. Park, K. H.	Korean J Thorac Cardiovasc Surg	2020	Coronary artery bypass grafting Critical care Intensive care unit staffing Intensivist Postoperative complications
Working Collaboratively: Outcomes of Geriatrician Input in Older Patients Undergoing Emergency Laparotomy in a District General Hospital	Khan, K. A. Subramanian, T. Richters, M. Mubarik, A. Saad Abdalla Al-Zawi, A. Thorn, C. C. Chalstrey, S. Gunasekera, S.	Cureus	2020	ageing & frailty cepod cognitive impairment elderly patients emergency laparotomy geriatric surgical liaison length of stay perioperative care
Postoperative delirium: the findings from a multidisciplinary survey	Jin, Z. Rahman, A. Pattnaik, S. Smith, M.	Psychogeriatrics	2020	education hypoactive delirium management postoperative delirium screening acute psychosis adult article complication diagnostic error education human mortality risk multidisciplinary team postoperative delirium prognosis surgery
Postoperative delirium after reconstructive surgery for oral tumor: a retrospective clinical study	Ishibashi-Kanno, N. Takaoka, S. Nagai, H. Okubo-Sato, M. Fukuzawa, S. Uchida, F. Yamagata, K. Yanagawa, T. Bukawa, H.	Int J Oral Maxillofac Surg	2020	Delirium Oral tumor Postoperative delirium Reconstructive surgery
Joining Forces against Delirium - From Organ-System Care to Whole-Human Care	Inouye, S. K.	N Engl J Med	2020	Aged Clinical Protocols Coronary Artery Bypass/adverse effects Delirium/diagnosis/etiology/ prevention & control Diagnostic Errors Humans Iatrogenic Disease/ prevention & control Male Cinical practice Evidence based practice Frailty Geriatric care Health care cost Health care delivery Health care policy Health care system Health program Hospital mortality Human Medicare Priority journal Reimbursement Review Vulnerable population
Incidence of and risk factors for postoperative delirium in older adult patients undergoing noncardiac surgery: a prospective study	Iamaroon, A. Wongviriyawong, T. Sura-Arunsumrit, P. Wiwatnodom, N. Rewuri, N. Chaiwat, O.	BMC Geriatr	2020	Collaborative approach Incidence Noncardiac surgery Older adult patients Postoperative delirium Risk factors aged anesthesiologist article Barthel index cognitive defect complication controlled study DSM-5 female geriatrician hematocrit high risk population hospitalization human incidence major clinical study male multidisciplinary team perioperative period peroperative complication postoperative delirium preoperative evaluation prospective study questionnaire risk factor surgery univariate analysis benzodiazepine opiate
Delirium misdiagnosis risk in psychiatry: a machine learning-logistic regression predictive algorithm	Hercus, C. Hudaib, A. R.	BMC Health Serv Res	2020	Delirium Input variables Machine learning-logistic classifier Misdiagnosis
Patterns of Potentially Inappropriate Bladder Antimuscarinic Use in People with Dementia: A Retrospective Cohort Study	Green, A. R. Segal, J. Boyd, C. M. Huang, J. Roth, D. L.	Drugs Real World Outcomes	2020
Incidence, determinants and consequences of delirium in older patients after transcatheter aortic valve implantation	Goudzwaard, J. A. de Ronde-Tillmans, Mjag de Jager, T. A. J. Lenzen, M. J. Nuis, R. J. van Mieghem, N. M. Daemen, J. de Jaegere, P. P. T. Mattace-Raso, F. U. S.	Age Ageing	2020	aortic stenosis mortality post-operative delirium transcatheter aortic valve implantation
Neuromonitoring of delirium with quantitative pupillometry in sedated mechanically ventilated critically ill patients	Favre, E. Bernini, A. Morelli, P. Pasquier, J. Miroz, J. P. Abed-Maillard, S. Ben-Hamouda, N. Oddo, M.	Crit Care	2020	Cholinergic Delirium Mechanical ventilation Pupillary reactivity Pupillometry
Cognitive Outcomes of Long-term Benzodiazepine and Related Drug (BDZR) Use in People Living With Mild to Moderate Alzheimer's Disease: Results From NILVAD	Dyer, A. H. Murphy, C. Lawlor, B. Kennelly, S. P.	J Am Med Dir Assoc	2020	Dementia Benzodiazepines Benzodiazepines and related drugs Cognition
'Nonagenarians' with a hip fracture: is a different orthogeriatric treatment strategy necessary?	de Groot, R. Nijmeijer, W. S. Folbert, E. C. Vollenbroek-Hutten, M. M. R. Hegeman, J. H.	Arch Osteoporos	2020	Frail elderly Hip fracture Nonagenarians Orthogeriatric Surgery
Comparison of single minimum dose administration of dexmedetomidine and midazolam for prevention of emergence delirium in children: a randomized controlled trial	Cho, E. A. Cha, Y. B. Shim, J. G. Ahn, J. H. Lee, S. H. Ryu, K. H.	J Anesth	2020	Dexmedetomidine Emergence agitation Emergence delirium Midazolam Pediatric anesthesia
Innovative care models across settings: Providing nursing care to older adults	Cacchione, P. Z.	Geriatr Nurs	2020	Evercare/Optum Interact Niche Pace Transitional Care Model
Is the bispectral index monitoring protective against postoperative cognitive decline? A systematic review with meta-analysis	Bocskai, T. Kovacs, M. Szakacs, Z. Gede, N. Hegyi, P. Varga, G. Pap, I. Toth, I. Revesz, P. Szanyi, I. Nemeth, A. Gerlinger, I. Karadi, K. Lujber, L.	PLoS One	2020	Anesthesia Metaanalysis Anesthesiology monitoring Surgical and invasive medical procedures Elderly General anesthesia Randomized controlled trials Cognitive impairment
Postanesthesia care unit delirium following robot-assisted vs open retropubic radical prostatectomy: A prospective observational study	Beck, S. Hoop, D. Ragab, H. Rademacher, C. Messner-Schmitt, A. von Breunig, F. Haese, A. Graefen, M. Zollner, C. Fischer, M.	Int J Med Robot	2020	Trendelenburg position anesthesia postoperative delirium postoperative neurocognitive disorders radical prostatectomy
The impact of Hospital Elder Life Program interventions, on 30-day readmission Rates of older hospitalized patients	Zachary, W. Kirupananthan, A. Cotter, S. Barbara, G. H. Cooke, R. C., 3rd Sipho, M.	Arch Gerontol Geriatr	2020	Cost savings Delirium Elderly Geriatric Older Readmission
Prevalence and risk factors for postoperative delirium in patients with colorectal carcinoma: a systematic review and meta-analysis	Yang, Z. Wang, X. F. Yang, L. F. Fang, C. Gu, X. K. Guo, H. W.	Int J Colorectal Dis	2020	Coloretal cancer Delirium Meta-analysis Prevalence Risk factor
Incidence, risk factors, and outcomes for sepsis-associated delirium in patients with mechanical ventilation: A sub-analysis of a multicenter randomized controlled trial	Yamamoto, T. Mizobata, Y. Kawazoe, Y. Miyamoto, K. Ohta, Y. Morimoto, T. Yamamura, H.	Journal of Critical Care	2020	fentanyl midazolam adult aged article artificial ventilation clinical outcome comparative study controlled study disease association emergency surgery extubation female hospitalization human incidence independent variable intensive care unit intubation length of stay major clinical study male mortality multicenter study predictor variable randomized controlled trial retrospective study risk factor self concept sepsis associated encephalopathy
Effects of different BP management strategies on postoperative delirium in elderly patients undergoing hip replacement: A single center randomized controlled trial	Xu, X. Hu, X. Wu, Y. Li, Y. Zhang, Y. Zhang, M. Yang, Q.	J Clin Anesth	2020	Blood pressure Hip replacement Postoperative delirium Regional cerebral oxygen saturation were involved in supporting this manuscript.
Preoperative prognostic nutritional index predicts postoperative delirium in elderly patients after hip fracture surgery	Xing, H. Xiang, D. Li, Y. Ji, X. Xie, G.	Psychogeriatrics	2020	elderly hip fracture postoperative delirium prognostic nutritional index
The effects of early femoral nerve block intervention on preoperative pain management and incidence of postoperative delirium geriatric patients undergoing trochanteric femur fracture surgery: A randomized controlled trial	Uysal, A. I. Altiparmak, B. Yasar, E. Turan, M. Canbek, U. Yilmaz, N. Gumus Demirbilek, S.	Ulus Travma Acil Cerrahi Derg	2020
A smartphone-based test for the assessment of attention deficits in delirium: A case-control diagnostic test accuracy study in older hospitalised patients	Tieges, Z. Stott, D. J. Shaw, R. Tang, E. Rutter, L. M. Nouzova, E. Duncan, N. Clarke, C. Weir, C. J. Assi, V. Ensor, H. Barnett, J. H. Evans, J. Green, S. Hendry, K. Thomson, M. McKeever, J. Middleton, D. G. Parks, S. Walsh, T. Weir, A. J. Wilson, E. Qua	PLoS One	2020
A 'real-world' analysis of risk factors for post liver transplant delirium and the effect on length of stay	Tavabie, O. D. Colwill, M. Adamson, R. McPhail, M. J. W. Bernal, W. Jassem, W. Prachialias, A. Heneghan, M. Aluvihare, V. R. Agarwal, K.	Eur J Gastroenterol Hepatol	2020
Intraoperative hypotension and delirium in patients with hip fracture	Tantardini, V. Roca, F. Bahri, O. Compere, V. Dujardin, F. Chassagne, P.	Geriatr Psychol Neuropsychiatr Vieil	2020	anaesthesia delirium hip fracture low blood pressure
Evaluation of emergence agitation after general anaesthesia in rhinoplasty patients: Inhalation anaesthesia versus total intravenous anaesthesia	Talih, G. Yüksek, A. Şahin, E.	American Journal of Otolaryngology - Head and Neck Medicine and Surgery	2020	adult anesthesia induction article bleeding controlled study emergence agitation female gas flow human image quality incidence intravenous anesthesia Likert scale low flow anesthesia lung alveolus major clinical study male nausea and vomiting nose reconstruction prospective study randomized controlled trial Richmond Agitation Sedation Scale satisfaction surgeon propofol sevoflurane
Implementation of a multiprofessional, multicomponent delirium management guideline in two intensive care units, and its effect on patient outcomes and nurse workload: a pre-post design retrospective cohort study	Schubert, M. Bettex, D. Steiger, P. Schurch, R. Haller, A. Bogdanovic, J. Garcia Nunez, D. Schwarz, U. Siegemund, M.	Swiss Med Wkly	2020
Cerebrospinal Fluid Levels of Interleukin-8 in Delirium, Dementia, and Cognitively Healthy Patients	Sajjad, M. U. Blennow, K. Knapskog, A. B. Idland, A. V. Chaudhry, F. A. Wyller, T. B. Zetterberg, H. Watne, L. O.	J Alzheimers Dis	2020	Alzheimer’s disease cytokines delirium depression
Prehospital Anticholinergic Burden Is Associated With Delirium but Not With Mortality in a Population of Acutely Ill Medical Patients	Rigor, J. Rueff Rato, I. Ferreira, P. M. Pereira, R. Ribeiro, C. Teixeira, D. Mesquita Oliveira, P. Silva, A. M. Pereira, S. Costa, I. Ferreira, P. Sequeira, M. Monteiro-Soares, M. Martins-Mendes, D.	J Am Med Dir Assoc	2020	Anticholinergic delirium geriatrics mortality
Impact of Vitamin C and Thiamine Administration on Delirium-Free Days in Patients with Septic Shock	Park, J. E. Shin, T. G. Jo, I. J. Jeon, K. Suh, G. Y. Park, M. Won, H. Chung, C. R. Hwang, S. Y.	J Clin Med	2020	delirium sepsis septic shock thiamine vitamin C
Evaluation of an updated sedation protocol to reduce benzodiazepines in a pediatric intensive care unit	Michel, J. Hofbeck, M. Peper, A. K. Kumpf, M. Neunhoeffer, F.	Curr Med Res Opin	2020	Cardiac surgery analgesia congenital heart disease nurse-driven protocol pediatric delirium withdrawal
A qualitative exploration of the views of patients and their relatives regarding interventions to minimize the distress related to postoperative delirium	Meilak, C. Biswell, E. Willis, R. Partridge, J. Dhesi, J.	Int J Geriatr Psychiatry	2020	aged article clinical article communication skill family stress female human information seeking male patient counseling patient education postoperative delirium qualitative research relative semi structured interview staff training thematic analysis very elderly
Incidence and risk factors of postoperative delirium in elderly patients undergoing urological surgery: A multi-institutional prospective study	Matsuki, M. Tanaka, T. Takahashi, A. Inoue, R. Hotta, H. Itoh, N. Taguchi, K. Kato, R. Kobayashi, K. Masumori, N.	Int J Urol	2020	elderly patients multicenter prospective cohort study postoperative delirium risk factors urological surgery
Still Predicting Delirium After All These Years	Marcantonio, ER	Anesth Analg	2020
Ketamine sedation in mechanically ventilated patients: A systematic review and meta-analysis	Manasco, A. T. Stephens, R. J. Yaeger, L. H. Roberts, B. W. Fuller, B. M.	Journal of Critical Care	2020	fentanyl hypertensive factor ketamine midazolam propofol agitation article artificial ventilation delirium drug infusion human hypertension length of stay meta analysis mortality randomized controlled trial (topic) risk benefit analysis side effect systematic review tachycardia
A Study of the Psychometric Properties of the “Stanford Proxy Test for Delirium” (S-PTD): A New Screening Tool for the Detection of Delirium	Maldonado, J. R. Sher, Y. I. Benitez-Lopez, M. A. Savant, V. Garcia, R. Ament, A. De Guzman, E.	Psychosomatics	2020	adult article controlled study delirium demography diagnosis diagnostic test accuracy study early diagnosis female hospitalization human major clinical study male middle aged nurse psychiatrist sensitivity and specificity
Risk factors for postoperative delirium after colorectal surgery: a systematic review and meta-analysis	Lee, S. H. Lim, S. W.	Int J Colorectal Dis	2020	Colorectal surgery Postoperative delirium Risk factor
Results from a double blinded, randomized, placebo-controlled, feasibility trial of melatonin for the treatment of delirium in older medical inpatients	Lange, P. W. Clayton-Chubb, D. I. Watson, R. Maier, A. B.	Intern Med J	2020	Delirium Melatonin Neurocognitive Disorders Post-Operative Cognitive Decline Sepsis-Associated Encephalopathy Sleep Treatment
Risk factors and outcomes among delirium subtypes in adult ICUs: A systematic review	Krewulak, K. D. Stelfox, H. T. Ely, E. W. Fiest, K. M.	J Crit Care	2020	Critical care Delirium Risk factors Subtype Systematic review any conflicts of interest relevant to this manuscript.
Survey of analgesia and sedation in pediatric intensive care units in Japan	Koizumi, T. Kurosawa, H.	Pediatr Int	2020	analgesia delirium pediatric intensive care units sedation withdrawal syndrome
Association of neuronal repair biomarkers with delirium among survivors of critical illness	Hayhurst, C. J. Patel, M. B. McNeil, J. B. Girard, T. D. Brummel, N. E. Thompson, J. L. Chandrasekhar, R. Ware, L. B. Pandharipande, P. P. Ely, E. W. Hughes, C. G.	Journal of Critical Care	2020	NCT00392795 brain derived neurotrophic factor interleukin 6 ubiquitin carboxyl terminal esterase L1 ubiquitin thiolesterase unclassified drug adult aged APACHE article Charlson Comorbidity Index clinical trial cohort analysis controlled study critically ill patient delirium disease duration female hospital admission human intensive care unit major clinical study male observational study pathophysiology population research prevalence prospective study protein blood level respiratory failure shock survivor
Dexmedetomidine's Relationship to Delirium in Patients Undergoing Cardiac Surgery: A Systematic Review	Halpin, E. Inch, H. O'Neill, M.	Crit Care Nurs Q	2020
Management of delirium at an academic medical center: Plans for antipsychotic prescribing upon discharge	Halavonich, L. Robert, S. McGraw, D. Weeda, E. Mullinax, K. Bass, B.	Ment Health Clin	2020	antipsychotic delirium discharge disclose.