What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Exercise for acutely hospitalised older medical patients
- Authors
- Hartley, P. Keating, J. L. Jeffs, K. J. Raymond, M. J. Smith, T. O
- Year
- 2022
- Journal
- Cochrane Database Syst Rev
- Abstract
BACKGROUND: Approximately 30% of hospitalised older adults experience hospital-associated functional decline. Exercise interventions that promote in-hospital activity may prevent deconditioning and thereby maintain physical function during hospitalisation. This is an update of a Cochrane Review first published in 2007. OBJECTIVES: To evaluate the benefits and harms of exercise interventions for acutely hospitalised older medical inpatients on functional ability, quality of life (QoL), participant global assessment of success and adverse events compared to usual care or a sham-control intervention. SEARCH METHODS: We used standard, extensive Cochrane search methods. The latest search date was May 2021. SELECTION CRITERIA: We included randomised or quasi-randomised controlled trials evaluating an in-hospital exercise intervention in people aged 65 years or older admitted to hospital with a general medical condition. We excluded people admitted for elective reasons or surgery. DATA COLLECTION AND ANALYSIS: We used standard Cochrane methods. Our major outcomes were 1. independence with activities of daily living; 2. functional mobility; 3. new incidence of delirium during hospitalisation; 4. QoL; 5. number of falls during hospitalisation; 6. medical deterioration during hospitalisation and 7. participant global assessment of success. Our minor outcomes were 8. death during hospitalisation; 9. musculoskeletal injuries during hospitalisation; 10. hospital length of stay; 11. new institutionalisation at hospital discharge; 12. hospital readmission and 13. walking performance. We used GRADE to assess certainty of evidence for each major outcome. We categorised exercise interventions as: rehabilitation-related activities (interventions designed to increase physical activity or functional recovery, but did not follow a specified exercise protocol); structured exercise (interventions that included an exercise intervention protocol but did not include progressive resistance training); and progressive resistance exercise (interventions that included an element of progressive resistance training). MAIN RESULTS: We included 24 studies (nine rehabilitation-related activity interventions, six structured exercise interventions and nine progressive resistance exercise interventions) with 7511 participants. All studies compared exercise interventions to usual care; two studies, in addition to usual care, used sham interventions. Mean ages ranged from 73 to 88 years, and 58% of participants were women. Several studies were at high risk of bias. The most common domain assessed at high risk of bias was measurement of the outcome, and five studies (21%) were at high risk of bias arising from the randomisation process. Exercise may have no clinically important effect on independence in activities of daily living at discharge from hospital compared to controls (16 studies, 5174 participants; low-certainty evidence). Five studies used the Barthel Index (scale: 0 to 100, higher scores representing greater independence). Mean scores at discharge in the control groups ranged from 42 to 96 points, and independence in activities of daily living was 1.8 points better (0.43 worse to 4.12 better) with exercise compared to controls. The minimally clinical important difference (MCID) is estimated to be 11 points. We are uncertain regarding the effect of exercise on functional mobility at discharge from the hospital compared to controls (8 studies, 2369 participants; very low-certainty evidence). Three studies used the Short Physical Performance Battery (SPPB) (scale: 0 to 12, higher scores representing better function) to measure functional mobility. Mean scores at discharge in the control groups ranged from 3.7 to 4.9 points on the SPPB, and the estimated effect of the exercise interventions was 0.78 points better (0.02 worse to 1.57 better). A change of 1 point on the SPPB represents an MCID. We are uncertain regarding the effect of exercise on the incidence of delirium during hospitalisation compared to controls (7 trials, 2088 participants; very low-certainty evidence). The incidence of delirium during hospitalisation was 88/1091 (81 per 1000) in the control group compared with 70/997 (73 per 1000; range 47 to 114) in the exercise group (RR 0.90, 95% CI 0.58 to 1.41). Exercise interventions may result in a small clinically unimportant improvement in QoL at discharge from the hospital compared to controls (4 studies, 875 participants; low-certainty evidence). Mean QoL on the EuroQol 5 Dimensions (EQ-5D) visual analogue scale (VAS) (scale: 0 to 100, higher scores representing better QoL) ranged between 48.9 and 64.7 in the control group at discharge from the hospital, and QoL was 6.04 points better (0.9 better to 11.18 better) with exercise. A change of 10 points on the EQ-5D VAS represents an MCID. No studies measured participant global assessment of success. Exercise interventions did not affect the risk of falls during hospitalisation (moderate-certainty evidence). The incidence of falls was 31/899 (34 per 1000) in the control group compared with 31/888 (34 per 1000; range 20 to 57) in the exercise group (RR 0.99, 95% CI 0.59 to 1.65). We are uncertain regarding the effect of exercise on the incidence of medical deterioration during hospitalisation (very low-certainty evidence). The incidence of medical deterioration in the control group was 101/1417 (71 per 1000) compared with 96/1313 (73 per 1000; range 44 to 120) in the exercise group (RR 1.02, 95% CI 0.62 to 1.68). Subgroup analyses by different intervention categories and by the use of a sham intervention were not meaningfully different from the main analyses. AUTHORS’ CONCLUSIONS: Exercise may make little difference to independence in activities of daily living or QoL, but probably does not result in more falls in older medical inpatients. We are uncertain about the effect of exercise on functional mobility, incidence of delirium and medical deterioration. Certainty of evidence was limited by risk of bias and inconsistency. Future primary research on the effect of exercise on acute hospitalisation could focus on more consistent and uniform reporting of participant’s characteristics including their baseline level of functional ability, as well as exercise dose, intensity and adherence that may provide an insight into the reasons for the observed inconsistencies in findings.
- PMID
- Keywords
Aged
Aged, 80 and over
Female
Humans
Male
Activities of Daily Living
*Delirium/epidemiology
Exercise
*Quality of Life
- Page(s)
- Volume
- Issue
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| Comprehensive analysis of in-hospital delirium after major surgical oncology procedures: A population-based study | Bandini, M. Marchioni, M. Preisser, F. Nazzani, S. Tian, Z. Graefen, M. Montorsi, F. Saad, F. Shariat, S. F. Schips, L. Briganti, A. Karakiewicz, P. I. | Can Urol Assoc J | 2020 |
adult |
| Sepsis Associated Delirium | Atterton, B. Paulino, M. C. Povoa, P. Martin-Loeches, I. | Medicina (Kaunas) | 2020 |
adult |
| Melatonin for delirium prevention in acute medically ill, and perioperative geriatric patients | Asleson, D. R. Chiu, A. W. | Aging Medicine | 2020 |
adult |
| The short- And long-term outcomes of esophagectomy for esophageal cancer in patients older than 75 years | Aoyama, T. Hara, K. Kazama, K. Atsumi, Y. Tamagawa, H. Tamagawa, A. MacHida, D. Komori, K. Maezawa, Y. Kano, K. Hashimoto, I. Oshima, T. Murakawa, M. Numata, M. Yukawa, N. Masuda, M. Rino, Y. | Anticancer Research | 2020 |
antineoplastic agent |
| National French survey of COVID-19 symptoms in people aged 70 and over | Annweiler, C. Sacco, G. Salles, N. Aquino, J. P. Gautier, J. Berrut, G. Guérin, O. Gavazzi, G. | Clin Infect Dis | 2020 | |
| COVID-19: ICU delirium management during SARS-CoV-2 pandemic-pharmacological considerations | Andrews, L. J. Benken, S. T. | Crit Care | 2020 |
Betacoronavirus |
| The Intersection of Architecture/Medicine/Quality and the Clinical Nurse Specialist: Designing for the Prevention of Delirium | Anderson, D. C. Jacoby, S. R. Scruth, E. A. | Clinical nurse specialist CNS | 2020 | |
| The Agents Intervening against Delirium in the Intensive Care Unit-Trial (AID-ICU trial):- a detailed statistical analysis plan | Andersen-Ranberg, N. Poulsen, L. M. Perner, A. Wetterslev, J. Mathiesen, O. Mortensen, C. B. Estrup, S. Ebdrup, B. H. Hästbacka, J. Citerio, G. Caballero, J. Morgan, M. P. G. Oxenbøll-Collet, M. Weber, S. O. Andreasen, A. S. Bestle, M. H. Pedersen, H. B | Acta Anaesthesiol Scand | 2020 | |
| A systematic review of the overlap of fluid biomarkers in delirium and advanced cancer-related syndromes | Amgarth-Duff, I. Hosie, A. Caplan, G. Agar, M. | BMC Psychiatry | 2020 |
Advanced cancer |
| Toward best practice methods for delirium biomarker studies: An international modified Delphi study | Amgarth-Duff, I. Hosie, A. Caplan, G. Agar, M. | Int J Geriatr Psychiatry | 2020 |
consensus |
| Preoperative cognitive dysfunction in older elective noncardiac surgical patients in South Africa | Amado, L. A. Perrie, H. Scribante, J. Ben-Israel, K. A. | Br J Anaesth | 2020 |
Mini-Cog |
| The etiology and age-related properties of patients with delirium in coronary intensive care unit and its effects on inhospital and follow up prognosis | Altay, S. Gürdoğan, M. Kaya, Ç Kardaş, F. Zeybey, U. Çakir, B. Ebik, M. Demir, M. | Ideggyogy Sz | 2020 |
delirium in coronary intensive care unit |
| A Unique Presentation of Delirium in a Patient with Otherwise Asymptomatic COVID-19 | Alkeridy, W. A. Almaghlouth, I. Alrashed, R. Alayed, K. Binkhamis, K. Alsharidi, A. Liu-Ambrose, T. | J Am Geriatr Soc | 2020 |
Covid-19 |
| Postoperative delirium after abdominal aortic surgery: after ICU discharge surveillance should extend to the surgical ward | Alessandri, F. Bilotta, F. | Minerva Anestesiol | 2020 | |
| The prevalence of emergence delirium and its associated factors among children at a postoperative unit: A retrospective cohort at a Middle Eastern hospital | Aldakhil, S. K. Salam, M. Albelali, A. A. Alkanhal, R. M. Alnemer, M. J. Alatassi, A. | Saudi J Anaesth | 2020 |
Anesthesia |
| Optimal goal of management of delirium in end-of-life cancer care | Akechi, T. | Lancet Oncol | 2020 | |
| Multiple Peri-Operative Complications are Associated with Reduced Long Term Amputation Free Survival Following Revascularisation for Lower Limb Peripheral Artery Disease: A Population Based Linked Data Study | Aitken, S. J. Randall, D. A. Noguchi, N. Blyth, F. M. Naganathan, V. | Eur J Vasc Endovasc Surg | 2020 |
Aged |
| Neurological manifestations and complications of COVID-19: A literature review | Ahmad, I. Rathore, F. A | J Clin Neurosci | 2020 |
Clinical features |
| The role of suvorexant in the prevention of delirium during acute hospitalization: A systematic review | Adams, A. D. Pepin, M. J. Brown, J. N. | J Crit Care | 2020 |
Belsomra |
| Quetiapine for delirium prophylaxis in high-risk critically ill patients | Abraham, M. P. Hinds, M. Tayidi, I. Jeffcoach, D. R. Corder, J. M. Hamilton, L. A. Lawson, C. M. Bollig, R. W. Heidel, R. E. Daley, B. J. Taylor, J. E. McMillen, J. C. | Surgeon | 2020 |
Delirium |
| Comparing outcomes after peripheral nerve block versus general anesthesia for lower extremity amputation: a nationwide exploratory retrospective cohort study in Japan | Abe, H. Sumitani, M. Matsui, H. Aso, S. Inoue, R. Fushimi, K. Uchida, K. Yasunaga, H. Yamada, Y. | Reg Anesth Pain Med | 2020 |
lower extremity |
| Development of delirium: Association with old age, severe burns, and intensive care | Abdelrahman, I. Vieweg, R. Irschik, S. Steinvall, I. Sjöberg, F. Elmasry, M. | Burns | 2020 |
Burns |
| Factors Associated With Postoperative Confusion and Prolonged Hospital Stay Following Deep Brain Stimulation Surgery for Parkinson Disease | Abboud, H. Genc, G. Saad, S. Thompson, N. Oravivattanakul, S. Alsallom, F. Yu, X. X. Floden, D. Gostkowski, M. Ahmed, A. Ezzeldin, A. Marouf, H. M. Mansour, O. Y. Fernandez, H. H. | Neurosurgery | 2020 |
Dbs |
| Mortality and complications after emergency laparotomy in patients above 80 years | Aakre, E. K. Ulvik, A. Hufthammer, K. O. Jammer, I. | Acta Anaesthesiol Scand | 2020 |
elderly |
| Evaluation of an emergency department falls pathway for older people: A patient chart review | O' Keeffe A O' Grady S Cronin, F. Dolan, C. O' Hea A O' Shea KL Naughton, C. | Int Emerg Nurs | 2020 | |
| Rapid in-person cognitive screening in the preoperative setting: Test considerations and recommendations from the Society for Perioperative Assessment and Quality Improvement (SPAQI) | Arias, F. Wiggins, M. Urman, R. D. Armstrong, R. Pfeifer, K. Bader, A. M. Libon, D. J. Chopra, A. Price, C. C. | Journal of Clinical Anesthesia | 2020 |
anesthesiology |
| Updated nomenclature of delirium and acute encephalopathy: statement of ten Societies | Slooter, A. J. C. Otte, W. M. Devlin, J. W. Arora, R. C. Bleck, T. P. Claassen, J. Duprey, M. S. Ely, E. W. Kaplan, P. W. Latronico, N. Morandi, A. Neufeld, K. J. Sharshar, T. MacLullich, A. M. J. Stevens, R. D. | Intensive Care Medicine | 2020 |
acute brain disease |
| Nonsedation or Light Sedation in Critically Ill, Mechanically Ventilated Patients | Olsen, H. T. Nedergaard, H. K. Strøm, T. Oxlund, J. Wian, K. A. Ytrebø, L. M. Kroken, B. A. Chew, M. Korkmaz, S. Lauridsen, J. T. Toft, P. | The New England journal of medicine | 2020 |
NCT01967680 |
| Ketamine Safety and Use in the Emergency Department for Pain and Agitation/Delirium: A Health System Experience | Mo, H. Campbell, M. J. Fertel, B. S. Lam, S. W. Wells, E. J. Casserly, E. Meldon, S. W. | The western journal of emergency medicine | 2020 |
adult |
| Impact of skeletal muscle mass on postoperative delirium in patients undergoing free flap repair after oral cancer resection | Makiguchi, T. Yamaguchi, T. Nakamura, H. Ogawa, M. Harimoto, N. Shirabe, K. Yokoo, S. | Journal of plastic surgery and hand surgery | 2020 |
adult |
| Identifying delirium in Parkinson disease: A pilot study | Lawson, R. A. Richardson, S. J. Yarnall, A. J. Burn, D. J. Allan, L. M. | International Journal of Geriatric Psychiatry | 2020 |
aged |
| Presurgical cognitive impairment is associated with postoperative delirium and postoperative cognitive dysfunction | Knaak, C. Brockhaus, W. R. Spies, C. Borchers, F. Piper, S. K. Radtke, F. M. Lachmann, G. | Minerva anestesiologica | 2020 |
aged |
| The effects of elective aortic repair, colorectal cancer surgery and subsequent postoperative delirium on long-term quality of life, cognitive functioning and depressive symptoms in older patients | Janssen, T. L. de Vries, J. Lodder, P. Faes, M. C. Ho, G. H. Gobardhan, P. D. van der Laan, L. | Aging & mental health | 2020 |
abdominal aortic aneurysm |
| American Society for Enhanced Recovery and Perioperative Quality Initiative Joint Consensus Statement on Postoperative Delirium Prevention | Hughes, C. G. Boncyk, C. S. Culley, D. J. Fleisher, L. A. Leung, J. M. McDonagh, D. L. Gan, T. J. McEvoy, M. D. Miller, T. E. | Anesthesia and analgesia | 2020 |
adult |
| Healthcare professionals' reports of cancer pain cues among older people with delirium: a qualitative-quantitative content analysis | Graham, C. A. Chaves, G. Harrison, R. Gauthier, L. R. Nissim, R. Zimmermann, C. Chan, V. Rodin, G. Stevens, B. Gagliese, L. | Journal of pain and symptom management | 2020 |
adult |
| Preoperative Cognitive Abnormality, Intraoperative Electroencephalogram Suppression, and Postoperative Delirium: A Mediation Analysis | Fritz, B. A. King, C. R. Ben Abdallah, A. Lin, N. Mickle, A. M. Budelier, T. P. Oberhaus, J. Park, D. Maybrier, H. R. Wildes, T. S. Avidan, M. S. Apakama, G. Aranake-Chrisinger, A. Bolzenius, J. Burton, J. Cui, V. Emmert, D. A. Goswami, S. Graetz, T. J. G | Anesthesiology | 2020 |
adult |
| Delirium screening and mortality in patients with dementia admitted to acute hospitals | Codling, D. Hood, C. Bassett, P. Smithard, D. Crawford, M. J. | Aging & mental health | 2020 |
aged |
| Do Neuroleptics Still Have a Role in Patients With Delirium? | Nikooie, R. Oh, E. S. Zhang, A. Robinson, K. A. Needham, D. M. | Annals of internal medicine | 2020 |
adult |
| Randomized clinical trial of intraoperative dexmedetomidine to prevent delirium in the elderly undergoing major non-cardiac surgery | Li, C. J. Wang, B. J. Mu, D. L. Hu, J. Guo, C. Li, X. Y. Ma, D. Wang, D. X. | British Journal of Surgery | 2020 |
ChiCTRIPR15007654 |
| Risk factors for adverse drug reactions in older inpatients of geriatric wards at admission: Multicenter study | Kojima, T. Matsui, T. Suzuki, Y. Takeya, Y. Tomita, N. Kozaki, K. Kuzuya, M. Rakugi, H. Arai, H. Akishita, M. | Geriatrics and Gerontology International | 2020 |
albumin |
| Real-world effectiveness of ramelteon and suvorexant for delirium prevention in 948 patients with delirium risk factors | Hatta, K. Kishi, Y. Wada, K. Takeuchi, T. Hashimoto, N. Suda, K. Taira, T. Tsuchida, K. Ohmori, T. Akizuki, N. Nishio, Y. Nakanishi, Y. Usui, C. Kurata, A. Horikawa, N. Eguchi, H. Ito, S. Muto, H. Nakamura, H. Uchimura, N. | Journal of Clinical Psychiatry | 2020 |
corticosteroid derivative |
| Independent Association Between Type of Intraoperative Blood Transfusion and Postoperative Delirium After Complex Spinal Fusion for Adult Deformity Correction | Elsamadicy, A. A. Adil, S. M. Charalambous, L. Drysdale, N. Koo, A. B. Lee, M. Kundishora, A. J. Camara-Quintana, J. Kolb, L. Laurans, M. Abbed, K. Karikari, I. O. | Spine | 2020 |
adult |
| Practices related to assessment of sedation, analgesia and delirium among critical care pediatricians in Brazil | Colleti Junior, J. Araujo, O. R. Andrade, A. B. Carvalho, W. B. | Einstein (Sao Paulo, Brazil) | 2020 |
analgesia |
| Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study | Chen, N. Zhou, M. Dong, X. Qu, J. Gong, F. Han, Y. Qiu, Y. Wang, J. Liu, Y. Wei, Y. Xia, J. Yu, T. Zhang, X. Zhang, L. | The Lancet | 2020 |
adult |
| Association between postoperative delirium and mortality in elderly patients undergoing hip fractures surgery: a meta-analysis | Bai, J. Liang, Y. Zhang, P. Liang, X. He, J. Wang, J. Wang, Y. | Osteoporosis International | 2020 |
article |
| Impact of frailty on short-term outcomes in patients undergoing transsphenoidal pituitary surgery | Asemota, A. O. Gallia, G. L. | Journal of Neurosurgery | 2020 |
acute heart infarction |
| Randomised controlled trial to investigate the relationship between mild hypercapnia and cerebral oxygen saturation in patients undergoing major surgery | Wong, C. Churilov, L. Cowie, D. Tan, C. O. Hu, R. Tremewen, D. Pearce, B. Pillai, P. Karalapillai, D. Bellomo, R. Weinberg, L. | BMJ Open | 2020 |
delirium |
| Establishment and validation of a delirium prediction model for neurosurgery patients in intensive care | Wang, J. Ji, Y. Wang, N. Chen, W. Bao, Y. Qin, Q. Ma, C. Xiao, Q. Li, S. | Int J Nurs Pract | 2020 |
delirium |
| Early mobilisation after transfemoral transcatheter aortic valve implantation: results of the MobiTAVI trial | Vendrik, J. Vlastra, W. van Mourik, M. S. Delewi, R. Beijk, M. A. Lemkes, J. Wykrzykowska, J. J. de Winter, R. J. Henriques, J. S. Piek, J. J. Vis, M. M. Koch, K. T. Baan, J., Jr. | Neth Heart J | 2020 |
Ambulation |
| Influence of sedation on delirium recognition in critically ill patients: A multinational cohort study | van den Boogaard, M. Wassenaar, A. van Haren, F. M. P. Slooter, A. J. C. Jorens, P. G. van der Jagt, M. Simons, K. S. Egerod, I. Burry, L. D. Beishuizen, A. Pickkers, P. Devlin, J. W. | Aust Crit Care | 2020 |
Assessment |
| Intraoperative reduction of vasopressors using processed electroencephalographic monitoring in patients undergoing elective cardiac surgery: a randomized clinical trial | Sponholz, C. Schuwirth, C. Koenig, L. Hoyer, H. Coldewey, S. M. Schelenz, C. Doenst, T. Kortgen, A. Bauer, M. | J Clin Monit Comput | 2020 |
Adverse events |
| Enhanced rehabilitation and care models for adults with dementia following hip fracture surgery | Smith, T. O. Gilbert, A. W. Sreekanta, A. Sahota, O. Griffin, X. L. Cross, J. L. Fox, C. Lamb, S. E. | Cochrane Database Syst Rev | 2020 | |
| Prospective Evaluation of Delirium in Geriatric Patients Undergoing Emergency General Surgery | Saljuqi, A. T. Hanna, K. Asmar, S. Tang, A. Zeeshan, M. Gries, L. Ditillo, M. Kulvatunyou, N. Castanon, L. Joseph, B. | J Am Coll Surg | 2020 | |
| Predisposing and Precipitating Factors Associated With Postoperative Delirium in Patients Undergoing Cardiac Surgery at a Veterans Affairs Medical Center: A Pilot Retrospective Analysis | Russell, M. D. Pinkerton, C. Sherman, K. A. Ebert, T. J. Pagel, P. S. | J Cardiothorac Vasc Anesth | 2020 |
Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition |
| Dopaminergic Hyperactivity in Neurological Patients with Delirium | Ramirez-Bermudez, J. Perez-Neri, I. Montes, S. Nente, F. Ramirez-Abascal, M. Carrillo-Mezo, R. Perez-Esparza, R. Soto-Hernandez, J. L. Espinola-Nadurille, M. Bayliss, L. De Jesus Flores Rivera, J. Rios, C. | Arch Med Res | 2020 |
Autoimmune limbic encephalitis |
| Effects of intravenous and mask induction on post-operative emergence delirium in pediatric patients undergoing tonsillectomy with or without adenoidectomy | Peker, K. Polat, R. | Ir J Med Sci | 2020 |
Intravenous induction |
| Safety and Tolerability of Rapid Administration Undiluted Levetiracetam | Morgan, O. Medenwald, B. | Neurocrit Care | 2020 |
Anticonvulsants |
| New use of psychotropic medication after hospitalization among people with dementia | Mollers, T. Perna, L. Stocker, H. Ihle, P. Schubert, I. Schottker, B. Frolich, L. Brenner, H. | Int J Geriatr Psychiatry | 2020 |
claims data |
| A logistic regression analysis comparing minimalistic approach and intubation anaesthesia in patients undergoing transfemoral transcatheter aortic valve replacement | Maier, A. Hammerich, B. Humburger, F. Brieschal, T. Heidt, T. Bothe, W. Schrofel, H. Kaier, K. Zehender, M. Reinohl, J. Bode, C. von Zur Muhlen, C. Stachon, P. | PLoS One | 2020 | |
| Anticipating Postoperative Delirium During Burst Suppression Using Electroencephalography | Ma, O. Crepeau, A. Z. Dutta, A. Bliss, D. | IEEE Trans Biomed Eng | 2020 |
adult |
| Can haloperidol prophylaxis reduce the incidence of delirium in critically ill patients in intensive care units? A systematic review and meta-analysis | Lin, P. Zhang, J. Shi, F. Liang, Z. A. | Heart Lung | 2020 |
Delirium |
| Benzodiazepines for treatment of patients with delirium excluding those who are cared for in an intensive care unit | Li, Y. Ma, J. Jin, Y. Li, N. Zheng, R. Mu, W. Wang, J. Si, J. H. Chen, J. Shang, H. C. | Cochrane Database Syst Rev | 2020 | |
| Delirium prevalence and prevention in patients with acute brain injury: A prospective before-and-after intervention study | Larsen, L. K. Moller, K. Petersen, M. Egerod, I. | Intensive Crit Care Nurs | 2020 |
Brain injuries |
| Postoperative anaemia might be a risk factor for postoperative delirium and prolonged hospital stay: A secondary analysis of a prospective cohort study | Kunz, J. V. Spies, C. D. Bichmann, A. Sieg, M. Mueller, A. | PLoS One | 2020 | |
| Development of a Simple and Practical Delirium Screening Tool for Use in Surgical Wards | Kubota, K. Suzuki, A. Ohde, S. Yamada, U. Fujitani, I. Koitabashi, A. | J Nurs Res | 2020 |
adult |
| Psychometric evaluation of the family caregiver ICU delirium knowledge questionnaire | Krewulak, K. D. Bull, M. J. Ely, E. W. Stelfox, H. T. Fiest, K. M. | BMC Health Serv Res | 2020 |
Critical care |
| The Impact of Acute Kidney Injury in the Perioperative Period on the Incidence of Postoperative Delirium in Patients Undergoing Coronary Artery Bypass Grafting-Observational Cohort Study | Kotfis, K. Slozowska, J. Listewnik, M. Szylinska, A. Rotter, I. | Int J Environ Res Public Health | 2020 |
Aki |
| Delirium point prevalence studies in inpatient settings: A systematic review and meta-analysis | Koirala, B. Hansen, B. R. Hosie, A. Budhathoki, C. Seal, S. Beaman, A. Davidson, P. M. | J Clin Nurs | 2020 |
delirium |
| Validity and Reliability of the Memorial Delirium Assessment Scale-Thai Version (MDAS-T) for Assessment of Delirium in Palliative Care Patients | Klankluang, W. Pukrittayakamee, P. Atsariyasing, W. Siriussawakul, A. Chanthong, P. Tongsai, S. Tayjasanant, S. | Oncologist | 2020 |
Delirium |
| The Impact of an Attending Intensivist on the Clinical Outcomes of Patients Admitted to the Cardiac Surgical Intensive Care Unit after Coronary Artery Bypass Grafting | Kim, D. J. Sohn, B. Kim, H. Chang, H. W. Lee, J. H. Kim, J. S. Lim, C. Park, K. H. | Korean J Thorac Cardiovasc Surg | 2020 |
Coronary artery bypass grafting |
| Working Collaboratively: Outcomes of Geriatrician Input in Older Patients Undergoing Emergency Laparotomy in a District General Hospital | Khan, K. A. Subramanian, T. Richters, M. Mubarik, A. Saad Abdalla Al-Zawi, A. Thorn, C. C. Chalstrey, S. Gunasekera, S. | Cureus | 2020 |
ageing & frailty |
| Postoperative delirium: the findings from a multidisciplinary survey | Jin, Z. Rahman, A. Pattnaik, S. Smith, M. | Psychogeriatrics | 2020 |
education |
| Postoperative delirium after reconstructive surgery for oral tumor: a retrospective clinical study | Ishibashi-Kanno, N. Takaoka, S. Nagai, H. Okubo-Sato, M. Fukuzawa, S. Uchida, F. Yamagata, K. Yanagawa, T. Bukawa, H. | Int J Oral Maxillofac Surg | 2020 |
Delirium |
| Joining Forces against Delirium - From Organ-System Care to Whole-Human Care | Inouye, S. K. | N Engl J Med | 2020 |
Aged |
| Incidence of and risk factors for postoperative delirium in older adult patients undergoing noncardiac surgery: a prospective study | Iamaroon, A. Wongviriyawong, T. Sura-Arunsumrit, P. Wiwatnodom, N. Rewuri, N. Chaiwat, O. | BMC Geriatr | 2020 |
Collaborative approach |
| Delirium misdiagnosis risk in psychiatry: a machine learning-logistic regression predictive algorithm | Hercus, C. Hudaib, A. R. | BMC Health Serv Res | 2020 |
Delirium |
| Patterns of Potentially Inappropriate Bladder Antimuscarinic Use in People with Dementia: A Retrospective Cohort Study | Green, A. R. Segal, J. Boyd, C. M. Huang, J. Roth, D. L. | Drugs Real World Outcomes | 2020 | |
| Incidence, determinants and consequences of delirium in older patients after transcatheter aortic valve implantation | Goudzwaard, J. A. de Ronde-Tillmans, Mjag de Jager, T. A. J. Lenzen, M. J. Nuis, R. J. van Mieghem, N. M. Daemen, J. de Jaegere, P. P. T. Mattace-Raso, F. U. S. | Age Ageing | 2020 |
aortic stenosis |
| Neuromonitoring of delirium with quantitative pupillometry in sedated mechanically ventilated critically ill patients | Favre, E. Bernini, A. Morelli, P. Pasquier, J. Miroz, J. P. Abed-Maillard, S. Ben-Hamouda, N. Oddo, M. | Crit Care | 2020 |
Cholinergic |
| Cognitive Outcomes of Long-term Benzodiazepine and Related Drug (BDZR) Use in People Living With Mild to Moderate Alzheimer's Disease: Results From NILVAD | Dyer, A. H. Murphy, C. Lawlor, B. Kennelly, S. P. | J Am Med Dir Assoc | 2020 |
Dementia |
| 'Nonagenarians' with a hip fracture: is a different orthogeriatric treatment strategy necessary? | de Groot, R. Nijmeijer, W. S. Folbert, E. C. Vollenbroek-Hutten, M. M. R. Hegeman, J. H. | Arch Osteoporos | 2020 |
Frail elderly |
| Comparison of single minimum dose administration of dexmedetomidine and midazolam for prevention of emergence delirium in children: a randomized controlled trial | Cho, E. A. Cha, Y. B. Shim, J. G. Ahn, J. H. Lee, S. H. Ryu, K. H. | J Anesth | 2020 |
Dexmedetomidine |
| Innovative care models across settings: Providing nursing care to older adults | Cacchione, P. Z. | Geriatr Nurs | 2020 |
Evercare/Optum |
| Is the bispectral index monitoring protective against postoperative cognitive decline? A systematic review with meta-analysis | Bocskai, T. Kovacs, M. Szakacs, Z. Gede, N. Hegyi, P. Varga, G. Pap, I. Toth, I. Revesz, P. Szanyi, I. Nemeth, A. Gerlinger, I. Karadi, K. Lujber, L. | PLoS One | 2020 |
Anesthesia |
| Postanesthesia care unit delirium following robot-assisted vs open retropubic radical prostatectomy: A prospective observational study | Beck, S. Hoop, D. Ragab, H. Rademacher, C. Messner-Schmitt, A. von Breunig, F. Haese, A. Graefen, M. Zollner, C. Fischer, M. | Int J Med Robot | 2020 |
Trendelenburg position |
| The impact of Hospital Elder Life Program interventions, on 30-day readmission Rates of older hospitalized patients | Zachary, W. Kirupananthan, A. Cotter, S. Barbara, G. H. Cooke, R. C., 3rd Sipho, M. | Arch Gerontol Geriatr | 2020 |
Cost savings |
| Prevalence and risk factors for postoperative delirium in patients with colorectal carcinoma: a systematic review and meta-analysis | Yang, Z. Wang, X. F. Yang, L. F. Fang, C. Gu, X. K. Guo, H. W. | Int J Colorectal Dis | 2020 |
Coloretal cancer |
| Incidence, risk factors, and outcomes for sepsis-associated delirium in patients with mechanical ventilation: A sub-analysis of a multicenter randomized controlled trial | Yamamoto, T. Mizobata, Y. Kawazoe, Y. Miyamoto, K. Ohta, Y. Morimoto, T. Yamamura, H. | Journal of Critical Care | 2020 |
fentanyl |
| Effects of different BP management strategies on postoperative delirium in elderly patients undergoing hip replacement: A single center randomized controlled trial | Xu, X. Hu, X. Wu, Y. Li, Y. Zhang, Y. Zhang, M. Yang, Q. | J Clin Anesth | 2020 |
Blood pressure |
| Preoperative prognostic nutritional index predicts postoperative delirium in elderly patients after hip fracture surgery | Xing, H. Xiang, D. Li, Y. Ji, X. Xie, G. | Psychogeriatrics | 2020 |
elderly |
| The effects of early femoral nerve block intervention on preoperative pain management and incidence of postoperative delirium geriatric patients undergoing trochanteric femur fracture surgery: A randomized controlled trial | Uysal, A. I. Altiparmak, B. Yasar, E. Turan, M. Canbek, U. Yilmaz, N. Gumus Demirbilek, S. | Ulus Travma Acil Cerrahi Derg | 2020 | |
| A smartphone-based test for the assessment of attention deficits in delirium: A case-control diagnostic test accuracy study in older hospitalised patients | Tieges, Z. Stott, D. J. Shaw, R. Tang, E. Rutter, L. M. Nouzova, E. Duncan, N. Clarke, C. Weir, C. J. Assi, V. Ensor, H. Barnett, J. H. Evans, J. Green, S. Hendry, K. Thomson, M. McKeever, J. Middleton, D. G. Parks, S. Walsh, T. Weir, A. J. Wilson, E. Qua | PLoS One | 2020 | |
| A 'real-world' analysis of risk factors for post liver transplant delirium and the effect on length of stay | Tavabie, O. D. Colwill, M. Adamson, R. McPhail, M. J. W. Bernal, W. Jassem, W. Prachialias, A. Heneghan, M. Aluvihare, V. R. Agarwal, K. | Eur J Gastroenterol Hepatol | 2020 | |
| Intraoperative hypotension and delirium in patients with hip fracture | Tantardini, V. Roca, F. Bahri, O. Compere, V. Dujardin, F. Chassagne, P. | Geriatr Psychol Neuropsychiatr Vieil | 2020 |
anaesthesia |
| Evaluation of emergence agitation after general anaesthesia in rhinoplasty patients: Inhalation anaesthesia versus total intravenous anaesthesia | Talih, G. Yüksek, A. Şahin, E. | American Journal of Otolaryngology - Head and Neck Medicine and Surgery | 2020 |
adult |
| Implementation of a multiprofessional, multicomponent delirium management guideline in two intensive care units, and its effect on patient outcomes and nurse workload: a pre-post design retrospective cohort study | Schubert, M. Bettex, D. Steiger, P. Schurch, R. Haller, A. Bogdanovic, J. Garcia Nunez, D. Schwarz, U. Siegemund, M. | Swiss Med Wkly | 2020 | |
| Cerebrospinal Fluid Levels of Interleukin-8 in Delirium, Dementia, and Cognitively Healthy Patients | Sajjad, M. U. Blennow, K. Knapskog, A. B. Idland, A. V. Chaudhry, F. A. Wyller, T. B. Zetterberg, H. Watne, L. O. | J Alzheimers Dis | 2020 |
Alzheimer’s disease |
| Prehospital Anticholinergic Burden Is Associated With Delirium but Not With Mortality in a Population of Acutely Ill Medical Patients | Rigor, J. Rueff Rato, I. Ferreira, P. M. Pereira, R. Ribeiro, C. Teixeira, D. Mesquita Oliveira, P. Silva, A. M. Pereira, S. Costa, I. Ferreira, P. Sequeira, M. Monteiro-Soares, M. Martins-Mendes, D. | J Am Med Dir Assoc | 2020 |
Anticholinergic |
| Impact of Vitamin C and Thiamine Administration on Delirium-Free Days in Patients with Septic Shock | Park, J. E. Shin, T. G. Jo, I. J. Jeon, K. Suh, G. Y. Park, M. Won, H. Chung, C. R. Hwang, S. Y. | J Clin Med | 2020 |
delirium |
| Evaluation of an updated sedation protocol to reduce benzodiazepines in a pediatric intensive care unit | Michel, J. Hofbeck, M. Peper, A. K. Kumpf, M. Neunhoeffer, F. | Curr Med Res Opin | 2020 |
Cardiac surgery |