What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Preoperative medication use and postoperative delirium: a systematic review.
- Authors
- Kassie, G. M. Nguyen, T. A. Kalisch Ellett, L. M. Pratt, N. L. Roughead, E. E.
- Year
- 2017
- Journal
- BMC Geriatr
- Abstract
BACKGROUND: Medications are frequently reported as both predisposing factors and inducers of delirium. This review evaluated the available evidence and determined the magnitude of risk of postoperative delirium associated with preoperative medication use. METHODS: A systematic search in Medline and EMBASE was conducted using MeSH terms and keywords for postoperative delirium and medication. Studies which included patients 18 years and older who underwent major surgery were included. The methodological quality of included studies was assessed independently by two authors using the Newcastle-Ottawa quality assessment scale for cohort studies. RESULTS: Twenty-nine studies; 25 prospective cohort, three retrospective cohort and one post hoc analysis of RCT data were included. Only four specifically aimed to assess medicines as an independent predictor of delirium, all other studies included medicines among a number of potential predictors of delirium. Of the studies specifically testing the association with a medication class, preoperative use of beta-blockers (OR = 2.06[1.18-3.60]) in vascular surgery and benzodiazepines RR 2.10 (1.23-3.59) prior to orthopedic surgery were significant. However, evidence is from single studies only. Where medicines were included as one possible factor among many, hypnotics had a similar risk estimate to the benzodiazepine study, with one significant and one non-significant result. Nifedipine use prior to cardiac surgery was found to be significantly associated with delirium. The non-specific grouping of psychoactive medication use preoperatively was generally higher with an associated two-to-seven-fold higher risk of postoperative delirium, while only two studies included narcotics without other agents, with one significant and one non-significant result. CONCLUSIONS: There was a limited number of high quality studies in the literature quantifying the direct association between preoperative medication use and postsurgical delirium. More studies are required to evaluate the association of specific preoperative medications on the risk of postoperative delirium so that comprehensive guidelines for medicine use prior to surgery can be developed to aid delirium prevention. TRIAL REGISTRATION: This systematic review has been registered on PROSPERO International prospective register of systematic reviews (Registration number: CRD42016051245 ).
- PMID
- Keywords
Adverse drug event
Delirium
Elderly
Medication
Medication related problem
Medication safety
Prevention
Risk factor
- Page(s)
- 298
- Volume
- 17
- Issue
- 1
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| A patient with lithium intoxication developing at therapeutic serum lithium levels and persistent delirium after discontinuation of its administration. | Omata N, Murata T, Omori M, Wada Y | General hospital psychiatry | 2003 |
Antipsychotic Agents, adverse effects, Delirium, drug therapy, Drug Administration Schedule, Humans, Lithium Carbonate, adverse effects, Male, Middle Aged, Time Factors |
| Excited delirium: does it exist? | Paquette M | Perspectives in psychiatric care | 2003 |
Death, Sudden, Delirium, complications, Humans, Police, Psychomotor Agitation, complications, Restraint, Physical, Violence, prevention & control |
| A prospective, open-label, flexible-dose study of quetiapine in the treatment of delirium. | Sasaki Y, Matsuyama T, Inoue S, Sunami T, Inoue T, Denda K, Koyama T | The Journal of clinical psychiatry | 2003 |
Aged, Aged, 80 and over, Antipsychotic Agents, adverse effects, Delirium, drug therapy, Dibenzothiazepines, adverse effects, Dose-Response Relationship, Drug, Female, Humans, Male, Middle Aged, Treatment Outcome |
| The Delirium Observation Screening Scale: a screening instrument for delirium. | Schuurmans MJ, Shortridge-Baggett LM, Duursma SA | Research and theory for nursing practice | 2003 |
Activities of Daily Living, Aged, Aged, 80 and over, Case-Control Studies, Delirium, diagnosis, Female, Geriatric Assessment, Humans, Male, Mass Screening, methods, Mental Status Schedule, Nursing Assessment, methods, Nursing Evaluation Research, Observation, methods, Prospective Studies, Psychometrics, Questionnaires, Risk Factors, Sensitivity and Specificity |
| Delirium in adults with intellectual disabilities and DC-LD. | Simpson N | Journal of intellectual disability research : JIDR | 2003 |
Aged, Aged, 80 and over, Delirium, complications, Diagnostic and Statistical Manual of Mental Disorders, Female, Humans, Intellectual Disability, complications, Male |
| Do guidelines improve the process and outcomes of care in delirium? | Young LJ, George J | Age and ageing | 2003 |
Aged, Delirium, diagnosis, Education, Medical, Continuing, Education, Nursing, Continuing, England, Geriatric Assessment, Geriatrics, education, Hospitals, General, standards, Humans, Mental Status Schedule, Outcome and Process Assessment (Health Care), Patient Care Planning, Practice Guidelines as Topic, Scotland |
| Association between cardiac and noncardiac complications in patients undergoing noncardiac surgery: outcomes and effects on length of stay. | Fleischmann KE, Goldman L, Young B, Lee TH | The American journal of medicine | 2003 |
Aged, Female, Heart Diseases, epidemiology, Humans, Length of Stay, statistics & numerical data, Linear Models, Logistic Models, Male, Myocardial Infarction, epidemiology, Odds Ratio, Postoperative Complications, classification, Prospective Studies, Pulmonary Edema, epidemiology, Risk Factors |
| Risk for acute confusion in sensory-impaired, rural, long-term-care elders. | Cacchione PZ, Culp K, Dyck MJ, Laing J | Clinical nursing research | 2003 |
Acute Disease, Aged, psychology, Aged, 80 and over, Confusion, epidemiology, Female, Geriatric Assessment, Hearing Disorders, complications, Homes for the Aged, Humans, Iowa, epidemiology, Long-Term Care, psychology, Longitudinal Studies, Male, Mass Screening, Nursing Homes, Prevalence, Risk Factors, Rural Population, Vision Disorders, complications |
| Mortality and morbidity in nonagenarian patients following hip fracture surgery. | Formiga F, Lopez-Soto A, Sacanella E, Coscojuela A, Suso S, Pujol R | Gerontology | 2003 |
Aged, Aged, 80 and over, Female, Femoral Neck Fractures, mortality, Follow-Up Studies, Frail Elderly, Humans, Male, Pain, Postoperative, Prospective Studies, Walking, physiology |
| The last forty-eight hours of life in a Portuguese palliative care unit: does it differ from elsewhere? | Gonçalves JF, Alvarenga M, Silva A | Journal of palliative medicine | 2003 |
Drug Utilization Review, Female, Humans, Male, Medical Audit, Neoplasms, nursing, Palliative Care, standards, Portugal, Prospective Studies, Terminal Care, standards |
| Systemic infection, interleukin 1beta, and cognitive decline in Alzheimer's disease. | Holmes C, El-Okl M, Williams AL, Cunningham C, Wilcockson D, Perry VH | Journal of neurology, neurosurgery, and psychiatry | 2003 |
Aged, Aged, 80 and over, Alzheimer Disease, etiology, Central Nervous System Bacterial Infections, complications, Cognition Disorders, diagnosis, Female, Follow-Up Studies, Humans, Interleukin-1, blood, Male, Neuropsychological Tests |
| Postoperative confusion in schizophrenic patients is affected by interleukin-6. | Kudoh A, Takase H, Takahira Y, Katagai H, Takazawa T | Journal of clinical anesthesia | 2003 |
Abdomen, surgery, Adult, Aged, Analgesia, Epidural, Anesthesia, Epidural, Anesthesia, General, Confusion, blood, Humans, Hydrocortisone, blood, Interleukin-6, blood, Middle Aged, Postoperative Complications, blood, Schizophrenia, blood |
| Treating depression in Alzheimer disease: efficacy and safety of sertraline therapy, and the benefits of depression reduction: the DIADS. | Lyketsos CG, DelCampo L, Steinberg M, Miles Q, Steele CD, Munro C, Baker AS, Sheppard JM, Frangakis C, Brandt J, Rabins PV | Archives of general psychiatry | 2003 |
Activities of Daily Living, psychology, Aged, Alzheimer Disease, drug therapy, Ambulatory Care, Caregivers, psychology, Cognition Disorders, diagnosis, Comorbidity, Depressive Disorder, drug therapy, Drug Administration Schedule, Female, Geriatric Assessment, Humans, Male, Mental Disorders, diagnosis, Neuropsychological Tests, Placebos, Psychiatric Status Rating Scales, Serotonin Uptake Inhibitors, therapeutic use, Sertraline, therapeutic use, Single-Blind Method, Treatment Outcome |
| Six-month neuropsychological outcome of medical intensive care unit patients. | Jackson JC, Hart RP, Gordon SM, Shintani A, Truman B, May L, Ely EW | Critical care medicine | 2003 |
APACHE, Cognition Disorders, diagnosis, Depression, diagnosis, Female, Humans, Intensive Care Units, Length of Stay, Male, Middle Aged, Neuropsychological Tests, Prospective Studies, Quality of Life, Respiration, Artificial, adverse effects |
| Clinical practice guidelines for the sustained use of sedatives and analgesics in the critically ill adult. | Jacobi J, Fraser GL, Coursin DB, Riker RR, Fontaine D, Wittbrodt ET, Chalfin DB, Masica MF, Bjerke HS, Coplin WM, Crippen DW, Fuchs BD, Kelleher RM, Marik PE, Nasraway SA, Murray MJ, Peruzzi WT, Lumb PD, | Critical care medicine | 2002 |
Adult, Analgesia, standards, Analgesics, administration & dosage, Conscious Sedation, standards, Critical Care, standards, Delirium, Humans, Hypnotics and Sedatives, administration & dosage, Pain Measurement, standards, Sleep, drug effects |
| Exposure to opioid analgesia in cognitively impaired and delirious elderly hip fracture patients. | Adunsky A, Levy R, Mizrahi E, Arad M | Archives of gerontology and geriatrics | 2002 | |
| Meperidine analgesia and delirium in aged hip fracture patients. | Adunsky A, Levy R, Heim M, Mizrahi E, Arad M | Archives of gerontology and geriatrics | 2002 | |
| Development and validation of a risk-adjustment index for older patients: the high-risk diagnoses for the elderly scale. | Desai MM, Bogardus ST, Williams CS, Vitagliano G, Inouye SK | Journal of the American Geriatrics Society | 2002 |
Aged, Female, Geriatrics, Health Status Indicators, Humans, Male, Prospective Studies, Risk Adjustment |
| Evaluation of a guided protocol for quality improvement in identifying common geriatric problems. | Bogardus ST, Richardson E, Maciejewski PK, Gahbauer E, Inouye SK | Journal of the American Geriatrics Society | 2002 |
Aged, Case-Control Studies, Clinical Protocols, Cohort Studies, Connecticut, Female, Geriatric Assessment, Hospitals, University, Humans, Male, Mass Screening, methods, Outpatient Clinics, Hospital, standards, Primary Health Care, Quality Assurance, Health Care |
| A review of physical restraint minimization in the acute and residential care settings. | Evans D, Wood J, Lambert L | Journal of advanced nursing | 2002 |
Accidental Falls, prevention & control, Acute Disease, Aged, Critical Care, methods, Education, Nursing, Continuing, Geriatric Nursing, methods, Health Services Research, Humans, Program Evaluation, Residential Facilities, organization & administration, Restraint, Physical, utilization |
| Delirium superimposed on dementia: a systematic review. | Fick DM, Agostini JV, Inouye SK | Journal of the American Geriatrics Society | 2002 |
Delirium, complications, Dementia, complications, Hospitalization, Humans, Prevalence, Prognosis, Randomized Controlled Trials as Topic, Research, Risk Factors |
| Iatrogenic causes of falls in hospitalised elderly patients: a case-control study. | Frels C, Williams P, Narayanan S, Gariballa SE | Postgraduate medical journal | 2002 |
Accidental Falls, prevention & control, Aged, Aged, 80 and over, Anti-Anxiety Agents, adverse effects, Benzodiazepines, Case-Control Studies, England, Female, Geriatric Assessment, Hospitalization, Humans, Logistic Models, Male, Odds Ratio, Risk Factors |
| Designing adverse event prevention programs using quality management methods: the case of falls in hospital. | Grenier-Sennelier C, Lombard I, Jeny-Loeper C, Maillet-Gouret MC, Minvielle E | International journal for quality in health care : journal of the International Society for Quality in Health Care / ISQua | 2002 |
Accidental Falls, prevention & control, Aged, Female, France, Health Services Research, Humans, Male, Program Development, Rehabilitation Centers, organization & administration, Risk Management, methods, Total Quality Management, methods |
| A novel approach to the prevention of postoperative delirium in the elderly after gastrointestinal surgery. | Aizawa K, Kanai T, Saikawa Y, Takabayashi T, Kawano Y, Miyazawa N, Yamamoto T | Surgery today | 2002 |
Aged, Aged, 80 and over, Analgesics, Opioid, administration & dosage, Anti-Anxiety Agents, administration & dosage, Delirium, etiology, Diazepam, administration & dosage, Digestive System Surgical Procedures, adverse effects, Drug Therapy, Combination, Female, Flunitrazepam, administration & dosage, Gastrointestinal Neoplasms, surgery, Humans, Infusions, Intravenous, Injections, Intramuscular, Male, Meperidine, administration & dosage, Postoperative Complications, prevention & control, Premedication, Prospective Studies |
| An open trial of olanzapine for the treatment of delirium in hospitalized cancer patients. | Breitbart W, Tremblay A, Gibson C | Psychosomatics | 2002 |
Adult, Aged, Aged, 80 and over, Analysis of Variance, Antipsychotic Agents, therapeutic use, Benzodiazepines, Chi-Square Distribution, Delirium, drug therapy, Female, Humans, Inpatients, psychology, Logistic Models, Male, Middle Aged, Neoplasms, complications, Pirenzepine, analogs & derivatives, Prospective Studies, Risk Factors, Severity of Illness Index |
| Delirium and psychotic symptoms--an integrative model. | Charlton BG, Kavanau JL | Medical hypotheses | 2002 |
Consciousness Disorders, Delirium, physiopathology, Electroconvulsive Therapy, Electroencephalography, Humans, Models, Psychological, Psychotic Disorders, physiopathology |
| Systematic detection and multidisciplinary care of delirium in older medical inpatients: a randomized trial. | Cole MG, McCusker J, Bellavance F, Primeau FJ, Bailey RF, Bonnycastle MJ, Laplante J | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne | 2002 |
Aged, Aged, 80 and over, Delirium, nursing, Female, Geriatric Assessment, Humans, Male, Patient Care Planning, Patient Care Team, Proportional Hazards Models, Quebec |
| Delirium after coronary bypass surgery evaluated by the organic brain syndrome protocol. | Eriksson M, Samuelsson E, Gustafson Y, Aberg T, Engström KG | Scandinavian cardiovascular journal : SCJ | 2002 |
Aged, Clinical Protocols, Coronary Artery Bypass, adverse effects, Coronary Disease, complications, Delirium, complications, Delirium, Dementia, Amnestic, Cognitive Disorders, complications, Female, Hallucinations, complications, Humans, Intensive Care, Length of Stay, Male, Postoperative Complications, diagnosis, Treatment Outcome |
| Delirium in patients undergoing hematopoietic stem cell transplantation. | Fann JR, Roth-Roemer S, Burington BE, Katon WJ, Syrjala KL | Cancer | 2002 |
Adult, Delirium, epidemiology, Female, Hematopoietic Stem Cell Transplantation, adverse effects, Humans, Logistic Models, Male, Middle Aged, Prospective Studies, Risk Factors |
| Delirium in acute stroke. | Ferro JM, Caeiro L, Verdelho A | Current opinion in neurology | 2002 |
Acute Disease, Delirium, epidemiology, Humans, Risk Factors, Stroke, epidemiology |
| Delirium in patients on hemodialysis therapy. | Fukunishi I, Kitaoka T, Shirai T, Kino K, Kanematsu E, Sato Y | Nephron | 2002 |
Aged, Delirium, epidemiology, Humans, Kidney Failure, Chronic, epidemiology, Prevalence, Renal Dialysis, adverse effects |
| Delirium in advanced cancer: a psychoeducational intervention for family caregivers. | Gagnon P, Charbonneau C, Allard P, Soulard C, Dumont S, Fillion L | Journal of palliative care | 2002 |
Adaptation, Psychological, Aged, Attitude of Health Personnel, Attitude to Health, Caregivers, education, Delirium, etiology, Family, psychology, Female, Focus Groups, Health Education, methods, Health Knowledge, Attitudes, Practice, Home Nursing, education, Humans, Male, Middle Aged, Neoplasms, complications, Pamphlets, Program Evaluation, Qualitative Research, Risk Factors, Teaching Materials, standards, Terminal Care, methods |
| The prevalence and documentation of impaired mental status in elderly emergency department patients. | Hustey FM, Meldon SW | Annals of emergency medicine | 2002 |
Aged, Aged, 80 and over, Cognition Disorders, diagnosis, Delirium, diagnosis, Emergency Service, Hospital, Female, Geriatric Assessment, Hospitals, Teaching, Humans, Male, Mental Disorders, diagnosis, Mental Status Schedule, Prevalence, Prospective Studies, Risk Factors, Urban Population |
| Deciphering the 4 D's: cognitive decline, delirium, depression and dementia--a review. | Insel KC, Badger TA | Journal of advanced nursing | 2002 |
Aged, Cognition Disorders, diagnosis, Delirium, diagnosis, Dementia, diagnosis, Depression, diagnosis, Humans, Task Performance and Analysis |
| Dementia and delirium in 4 patients with Machado-Joseph disease. | Ishikawa A, Yamada M, Makino K, Aida I, Idezuka J, Ikeuchi T, Soma Y, Takahashi H, Tsuji S | Archives of neurology | 2002 |
Delirium, complications, Dementia, complications, Female, Humans, Machado-Joseph Disease, complications, Male, Middle Aged |
| Delirium resulting from paraneoplastic limbic encephalitis caused by Hodgkin's disease. | Kung S, Mueller PS, Geda YE, Krahn LE | Psychosomatics | 2002 |
Delirium, etiology, Female, Hodgkin Disease, complications, Humans, Limbic Encephalitis, complications, Middle Aged, Psychiatric Status Rating Scales |
| Anticipating and preventing delirium. | Lampley-Dallas VT | The Journal of the Oklahoma State Medical Association | 2002 |
Aged, Aged, 80 and over, Delirium, diagnosis, Female, Humans, Male |
| Confusion assessment method in the diagnostics of delirium among aged hospital patients: would it serve better in screening than as a diagnostic instrument? | Laurila JV, Pitkala KH, Strandberg TE, Tilvis RS | International journal of geriatric psychiatry | 2002 |
Aged, Aged, 80 and over, Algorithms, Confusion, Cross-Sectional Studies, Delirium, diagnosis, Female, Hospitalization, Humans, Male, Psychiatric Status Rating Scales, standards, Sensitivity and Specificity |
| Delirium and dehydration: some fluid for thought? | Lawlor PG | Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer | 2002 |
Analgesics, Opioid, adverse effects, Dehydration, complications, Delirium, chemically induced, Diagnostic Errors, Family, psychology, Fluid Therapy, Humans, Neoplasms, complications, Palliative Care, methods, Water-Electrolyte Balance, physiology |
| Intractable delirium associated with ziconotide successfully treated with electroconvulsive therapy. | Levin T, Petrides G, Weiner J, Saravay S, Multz AS, Bailine S | Psychosomatics | 2002 |
Adult, Analgesics, adverse effects, Calcium Channel Blockers, adverse effects, Delirium, chemically induced, Electroconvulsive Therapy, Humans, Male, Peripheral Nervous System Diseases, drug therapy, omega-Conotoxins, administration & dosage |
| Delirium predicts 12-month mortality. | McCusker J, Cole M, Abrahamowicz M, Primeau F, Belzile E | Archives of internal medicine | 2002 |
Aged, Confounding Factors (Epidemiology), Delirium, complications, Dementia, complications, Hospitalization, Humans, Mortality, Prognosis, Proportional Hazards Models, Prospective Studies, Severity of Illness Index, Survival Analysis |
| Documentation of delirium in elderly patients with hip fracture. | Milisen K, Foreman MD, Wouters B, Driesen R, Godderis J, Abraham IL, Broos PL | Journal of gerontological nursing | 2002 |
Age Factors, Aged, Aged, 80 and over, Delirium, diagnosis, Documentation, standards, Female, Hip Fractures, classification, Humans, Male, Medical Records, statistics & numerical data, Nursing Records, standards, Postoperative Complications, diagnosis, Retrospective Studies |
| Confusion/delirium following cataract surgery: an incidence study of 1-year duration. | Milstein A, Pollack A, Kleinman G, Barak Y | International psychogeriatrics / IPA | 2002 |
Adult, Age Factors, Aged, Aged, 80 and over, Cataract Extraction, Confusion, diagnosis, Delirium, diagnosis, Female, Humans, Incidence, Longitudinal Studies, Male, Middle Aged, Postoperative Complications, Severity of Illness Index |
| Acute postoperative delirium: definitions, incidence, recognition, and interventions. | O'Brien D | Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses / American Society of PeriAnesthesia Nurses | 2002 |
Acute Disease, Delirium, epidemiology, Humans, Incidence, Nursing Assessment, Postanesthesia Nursing, methods |
| Delirium: an important (but often unrecognized) clinical syndrome. | Rabinowitz T | Current psychiatry reports | 2002 |
Delirium, psychology, Humans, Risk Factors |
| Delirium. Pragmatic guidance for managing a common, confounding, and sometimes lethal condition. | Samuels SC, Evers MM | Geriatrics | 2002 |
Aged, Anti-Anxiety Agents, therapeutic use, Antipsychotic Agents, therapeutic use, Delirium, drug therapy, Diagnosis, Differential, Geriatric Assessment, Humans |
| Assessing for delirium. | Schofield I | Nursing older people | 2002 |
Age Factors, Aged, Delirium, diagnosis, Humans |
| Agitated delirium and sudden death. | Vilke GM, Chan TC | Prehospital emergency care : official journal of the National Association of EMS Physicians and the National Association of State EMS Directors | 2002 |
Adult, Asphyxia, etiology, Death, Sudden, etiology, Delirium, complications, Emergency Medical Services, Female, Humans, Immobilization, adverse effects, Male, Middle Aged, Restraint, Physical, United States |
| Confusion assessment method (CAM). | Waszynski CM | Insight (American Society of Ophthalmic Registered Nurses) | 2002 |
Delirium, diagnosis, Humans, Psychological Tests, Reproducibility of Results |
| A case study of postoperative delirium. | Wendel I | AORN journal | 2002 |
Age Factors, Aged, Aged, 80 and over, Delirium, diagnosis, Dementia, complications, Geriatric Assessment, Humans, Male, Nursing Assessment, Operating Room Nursing, methods, Pain, Postoperative, complications, Postoperative Complications, diagnosis, Preoperative Care, Risk Factors |
| Delirium severity and psychomotor types: their relationship with outcomes after hip fracture repair. | Marcantonio E, Ta T, Duthie E, Resnick NM | Journal of the American Geriatrics Society | 2002 |
Aged, Aged, 80 and over, Cohort Studies, Delirium, etiology, Female, Hip Fractures, complications, Humans, Length of Stay, Male, Nursing Homes, Outcome Assessment (Health Care), Prospective Studies, Psychomotor Disorders, complications, Recovery of Function, physiology, Severity of Illness Index |
| Symptoms of delirium among elderly medical inpatients with or without dementia. | Cole MG, McCusker J, Dendukuri N, Han L | The Journal of neuropsychiatry and clinical neurosciences | 2002 |
Adult, Aged, Aged, 80 and over, Cluster Analysis, Delirium, diagnosis, Dementia, complications, Female, Hospitalization, Humans, Male, Middle Aged, Prevalence, Psychiatric Status Rating Scales, Psychomotor Disorders, epidemiology, Severity of Illness Index |
| Cortisol response to surgery and postoperative confusion in depressed patients under general anesthesia with fentanyl. | Kudoh A, Takahira Y, Katagai H, Takazawa T | Neuropsychobiology | 2002 |
Adrenocorticotropic Hormone, blood, Adult, Anesthesia, General, adverse effects, Anesthetics, Intravenous, administration & dosage, Case-Control Studies, Confusion, blood, Depressive Disorder, blood, Fentanyl, administration & dosage, Humans, Hydrocortisone, blood, Middle Aged, Narcotics, adverse effects, Orthopedic Procedures, Postoperative Complications, blood, Propofol, adverse effects, Time Factors |
| Schizophrenic patients who develop postoperative confusion have an increased norepinephrine and cortisol response to surgery. | Kudoh A, Takahira Y, Katagai H, Takazawa T | Neuropsychobiology | 2002 |
Adrenocorticotropic Hormone, blood, Adult, Aged, Case-Control Studies, Confusion, blood, Female, Humans, Hydrocortisone, blood, Male, Middle Aged, Norepinephrine, blood, Postoperative Complications, blood, Schizophrenia, blood, Time Factors |
| Anesthesia with ketamine, propofol, and fentanyl decreases the frequency of postoperative psychosis emergence and confusion in schizophrenic patients. | Kudoh A, Katagai H, Takazawa T | Journal of clinical anesthesia | 2002 |
Adult, Aged, Anesthesia, General, Anesthesia, Intravenous, Anesthetics, Dissociative, adverse effects, Anesthetics, Intravenous, Confusion, chemically induced, Female, Fentanyl, Fractures, Bone, surgery, Humans, Ketamine, adverse effects, Male, Middle Aged, Postoperative Complications, psychology, Propofol, Prospective Studies, Psychoses, Substance-Induced, etiology, Schizophrenic Psychology |
| Small-dose ketamine improves the postoperative state of depressed patients. | Kudoh A, Takahira Y, Katagai H, Takazawa T | Anesthesia and analgesia | 2002 |
Adult, Anesthesia, General, Anesthetics, Dissociative, Blood Loss, Surgical, Depressive Disorder, psychology, Female, Humans, Ketamine, Male, Middle Aged, Pain Measurement, Pain, Postoperative, psychology, Postoperative Period, Psychiatric Status Rating Scales |
| Antidepressant treatment for chronic depressed patients should not be discontinued prior to anesthesia. | Kudoh A, Katagai H, Takazawa T | Canadian journal of anaesthesia = Journal canadien d'anesthésie | 2002 |
Adult, Anesthesia, Antidepressive Agents, adverse effects, Arrhythmias, Cardiac, epidemiology, Chronic Disease, Confusion, etiology, Depression, drug therapy, Hemodynamics, Humans, Hypotension, epidemiology, Intraoperative Complications, etiology, Middle Aged |
| Preoperative factors associated with postoperative change in confusion assessment method score in hip fracture patients. | Zakriya KJ, Christmas C, Wenz JF, Franckowiak S, Anderson R, Sieber FE | Anesthesia and analgesia | 2002 |
Age Factors, Aged, Aged, 80 and over, Analysis of Variance, Confusion, diagnosis, Female, Hip Fractures, surgery, Humans, Leukocyte Count, Logistic Models, Male, Middle Aged, Neuropsychological Tests, Odds Ratio, Orthopedic Procedures, adverse effects, Postoperative Complications, epidemiology, Preoperative Care, Risk Factors, Sodium, blood |
| Patients with hip fracture: subgroups and their outcomes. | Eastwood EA, Magaziner J, Wang J, Silberzweig SB, Hannan EL, Strauss E, Siu AL | Journal of the American Geriatrics Society | 2002 |
Activities of Daily Living, Aged, Aged, 80 and over, Cluster Analysis, Decision Trees, Female, Geriatric Assessment, Hip Fractures, physiopathology, Hospitalization, Humans, Male, New York City, Outcome Assessment (Health Care), Prospective Studies, Treatment Outcome |
| Improving medication use in newly admitted home healthcare patients: a randomized controlled trial. | Meredith S, Feldman P, Frey D, Giammarco L, Hall K, Arnold K, Brown NJ, Ray WA | Journal of the American Geriatrics Society | 2002 |
Aged, Drug Therapy, standards, Follow-Up Studies, Home Care Agencies, Home Care Services, standards, Humans, Interviews as Topic, Outcome Assessment (Health Care) |
| A scale for measuring patient perceptions of the quality of end-of-life care and satisfaction with treatment: the reliability and validity of QUEST. | Sulmasy DP, McIlvane JM, Pasley PM, Rahn M | Journal of pain and symptom management | 2002 |
Aged, Female, Humans, Male, Palliative Care, standards, Patient Satisfaction, Quality Assurance, Health Care, methods, Reproducibility of Results |
| Patients' ratings of quality and satisfaction with care at the end of life. | Sulmasy DP, McIlvane JM | Archives of internal medicine | 2002 |
Academic Medical Centers, standards, Adult, Aged, Aged, 80 and over, Analysis of Variance, Cross-Sectional Studies, District of Columbia, Female, Hospice Care, psychology, Humans, Internship and Residency, standards, Male, Middle Aged, New York, Nurse-Patient Relations, Outcome Assessment (Health Care), Palliative Care, psychology, Patient Satisfaction, Physician-Patient Relations, Quality Assurance, Health Care, Quality of Life, Questionnaires, Resuscitation Orders |
| Antipsychotics and dopamine transporter gene polymorphisms in delirium patients. | Kim JY, Jung IK, Han C, Cho SH, Kim L, Kim SH, Lee BH, Lee HJ, Kim YK | Psychiatry and clinical neurosciences | 2005 |
Adult, Antipsychotic Agents, administration & dosage, Delirium, drug therapy, Dopamine Plasma Membrane Transport Proteins, Female, Haloperidol, administration & dosage, Humans, Korea, Male, Membrane Glycoproteins, genetics, Membrane Transport Proteins, genetics, Nerve Tissue Proteins, genetics, Polymorphism, Genetic, genetics, Psychiatric Status Rating Scales, Reverse Transcriptase Polymerase Chain Reaction, Risperidone, administration & dosage |
| Outcomes of older people admitted to postacute facilities with delirium. | Marcantonio ER, Kiely DK, Simon SE, John Orav E, Jones RN, Murphy KM, Bergmann MA | Journal of the American Geriatrics Society | 2005 |
Accidental Falls, statistics & numerical data, Acute Disease, Aged, Aged, 80 and over, Cohort Studies, Comorbidity, Dehydration, epidemiology, Delirium, epidemiology, Female, Heart Failure, epidemiology, Homes for the Aged, statistics & numerical data, Humans, Male, Massachusetts, epidemiology, Nursing Homes, statistics & numerical data, Outcome Assessment (Health Care), Pneumonia, epidemiology, Proportional Hazards Models, Skin Diseases, epidemiology, Survival Analysis, Urinary Tract Infections, epidemiology |
| Large-scale implementation of sedation and delirium monitoring in the intensive care unit: a report from two medical centers. | Pun BT, Gordon SM, Peterson JF, Shintani AK, Jackson JC, Foss J, Harding SD, Bernard GR, Dittus RS, Ely EW | Critical care medicine | 2005 |
Adult, Aged, Critical Care, standards, Delirium, nursing, Drug Utilization Review, Female, Guideline Adherence, Hospitals, University, Hospitals, Veterans, Humans, Hypnotics and Sedatives, administration & dosage, Intensive Care Units, standards, Male, Middle Aged, Nursing Assessment, Outcome and Process Assessment (Health Care), Prospective Studies, Respiration, Artificial, nursing, Tennessee |
| Prevalence, course, and risk factors for executive impairment in patients hospitalized on a general medicine service. | Schillerstrom JE, Horton MS, Schillerstrom TL, Joshi KG, Earthman BS, Velez AM, Royall DR | Psychosomatics | 2005 |
Cognition Disorders, diagnosis, Female, Hospitalization, Hospitals, General, Humans, Male, Middle Aged, Neuropsychological Tests, Prevalence, Risk Factors, Texas, epidemiology |
| Delirium: a process improvement approach to changing prescribing practices in a community teaching hospital. | Pierre JS | Journal of nursing care quality | 2005 |
Aged, Attitude of Health Personnel, Delirium, chemically induced, Drug Prescriptions, standards, Drug Utilization Review, Education, Medical, Continuing, organization & administration, Geriatric Assessment, Geriatrics, education, Health Knowledge, Attitudes, Practice, Health Services Needs and Demand, Hospitals, Community, Hospitals, Teaching, Humans, Incidence, Medical Staff, Hospital, education, Midwestern United States, epidemiology, Outcome and Process Assessment (Health Care), organization & administration, Patient Care Team, organization & administration, Physician’s Practice Patterns, standards, Prevalence, Professional Staff Committees, organization & administration, Risk Factors, Total Quality Management, organization & administration |
| Educational disadvantage impairs functional recovery after hospitalization in older persons. | Chaudhry SI, Friedkin RJ, Horwitz RI, Inouye SK | The American journal of medicine | 2004 |
Activities of Daily Living, Aged, Aged, 80 and over, Cohort Studies, Data Collection, Educational Status, Female, Geriatric Assessment, Hospitalization, statistics & numerical data, Humans, Male, Multivariate Analysis, Prospective Studies, Recovery of Function |
| Translating research into clinical practice: making change happen. | Bradley EH, Schlesinger M, Webster TR, Baker D, Inouye SK | Journal of the American Geriatrics Society | 2004 |
Aged, Diffusion of Innovation, Evidence-Based Medicine, Health Services Research, Health Services for the Aged, manpower, Humans, Interviews as Topic, Organizational Innovation, Organizational Objectives, Program Development, Program Evaluation, Quality Assurance, Health Care, United States |
| Prevalence and outcomes of low mobility in hospitalized older patients. | Brown CJ, Friedkin RJ, Inouye SK | Journal of the American Geriatrics Society | 2004 |
Activities of Daily Living, Aged, Bed Rest, Cohort Studies, Female, Humans, Iatrogenic Disease, Inpatients, Locomotion, physiology, Male, Prevalence, Prospective Studies |
| Achieving goals in geriatric assessment: role of caregiver agreement and adherence to recommendations. | Bogardus ST, Bradley EH, Williams CS, Maciejewski PK, Gallo WT, Inouye SK | Journal of the American Geriatrics Society | 2004 |
Aged, Caregivers, Female, Geriatric Assessment, Goals, Guideline Adherence, Humans, Interviews as Topic, Male, Prospective Studies, Regression Analysis |
| Translating research into practice: speeding the adoption of innovative health care programs. | Bradley EH, Webster TR, Baker D, Schlesinger M, Inouye SK, Barth MC, Lapane KL, Lipson D, Stone R, Koren MJ | Issue brief (Commonwealth Fund) | 2004 |
Decision Making, Organizational, Diffusion of Innovation, Health Services Research, utilization, Humans, Information Dissemination, Interdepartmental Relations, Leadership, Organizational Culture, Research, Time Factors |
| [Incidence and risk factors of delirium after hip surgery]. | Bickel H, Gradinger R, Kochs E, Wagner K, Förstl H | Psychiatrische Praxis | 2004 |
Aged, Aged, 80 and over, Anesthesia, General, Arthroplasty, Replacement, Hip, Comorbidity, Delirium, epidemiology, Female, Hip Fractures, surgery, Humans, Incidence, Male, Middle Aged, Postoperative Complications, epidemiology, Risk Factors |
| Current opinions regarding the importance, diagnosis, and management of delirium in the intensive care unit: a survey of 912 healthcare professionals. | Ely EW, Stephens RK, Jackson JC, Thomason JW, Truman B, Gordon S, Dittus RS, Bernard GR | Critical care medicine | 2004 |
Aged, Aged, 80 and over, Attitude of Health Personnel, Critical Care, standards, Delirium, diagnosis, Female, Health Care Surveys, Humans, Intensive Care Units, standards, Male, Prognosis, Quality of Health Care, Questionnaires, Respiration, Artificial, Risk Assessment, Survival Analysis, Treatment Outcome, United States, epidemiology |
| Costs associated with delirium in mechanically ventilated patients. | Milbrandt EB, Deppen S, Harrison PL, Shintani AK, Speroff T, Stiles RA, Truman B, Bernard GR, Dittus RS, Ely EW | Critical care medicine | 2004 |
APACHE, Adult, Aged, Costs and Cost Analysis, Delirium, economics, Female, Glasgow Coma Scale, Hospital Charges, statistics & numerical data, Hospital Costs, statistics & numerical data, Humans, Intensive Care, economics, Male, Middle Aged, Respiration, Artificial, economics, United States |
| How do delirium and dementia increase length of stay of elderly general medical inpatients? | Saravay SM, Kaplowitz M, Kurek J, Zeman D, Pollack S, Novik S, Knowlton S, Brendel M, Hoffman L | Psychosomatics | 2004 |
Aged, Cognition Disorders, diagnosis, Delirium, complications, Dementia, complications, Female, Hospitalization, Humans, Length of Stay, statistics & numerical data, Male, Mental Disorders, etiology, Neuropsychological Tests |
| Drug therapy for delirium in terminally ill patients. | Jackson KC, Lipman AG | The Cochrane database of systematic reviews | 2004 |
Antipsychotic Agents, therapeutic use, Chlorpromazine, therapeutic use, Delirium, drug therapy, Haloperidol, therapeutic use, Humans, Lorazepam, therapeutic use, Terminally Ill, psychology |
| The delirium index, a measure of the severity of delirium: new findings on reliability, validity, and responsiveness. | McCusker J, Cole MG, Dendukuri N, Belzile E | Journal of the American Geriatrics Society | 2004 |
Activities of Daily Living, Aged, Cognition, Comorbidity, Delirium, classification, Dementia, complications, Female, Humans, Male, Prospective Studies, Reproducibility of Results, Severity of Illness Index |
| Effect of postoperative delirium on outcome after hip fracture. | Edelstein DM, Aharonoff GB, Karp A, Capla EL, Zuckerman JD, Koval KJ | Clinical orthopaedics and related research | 2004 |
Age Factors, Aged, Aged, 80 and over, Analysis of Variance, Cohort Studies, Delirium, epidemiology, Female, Fracture Fixation, Internal, adverse effects, Fracture Healing, physiology, Hip Fractures, diagnosis, Humans, Incidence, Male, Multivariate Analysis, Postoperative Complications, diagnosis, Probability, Prognosis, Retrospective Studies, Risk Assessment, Sex Factors, Survival Analysis |
| Admission characteristics of trauma patients in whom delirium develops. | Blondell RD, Powell GE, Dodds HN, Looney SW, Lukan JK | American journal of surgery | 2004 |
Age Distribution, Case-Control Studies, Critical Care, Delirium, diagnosis, Female, Hospitalization, Humans, Incidence, Injury Severity Score, Logistic Models, Male, Multiple Trauma, diagnosis, Odds Ratio, Patient Admission, standards, Predictive Value of Tests, Probability, Prognosis, Risk Assessment, Sex Distribution, Survival Rate, Time Factors, Trauma Centers |
| An approach to drug induced delirium in the elderly. | Alagiakrishnan K, Wiens CA | Postgraduate medical journal | 2004 |
Aged, Anti-Inflammatory Agents, Non-Steroidal, adverse effects, Central Nervous System Agents, adverse effects, Complementary Therapies, adverse effects, Delirium, chemically induced, Disease Susceptibility, Humans, Respiratory System Agents, adverse effects |
| Delirium doulas: an innovative approach to enhance care for critically ill older adults. | Balas MC, Gale M, Kagan SH | Critical care nurse | 2004 |
Aged, Critical Care, methods, Critical Illness, Delirium, nursing, Female, Geriatric Nursing, methods, Humans, Nurse’s Role, Obstetric Nursing, education, Pregnancy, Program Development, Volunteers, organization & administration |
| Delirium symptoms and low dietary intake in older inpatients are independent predictors of institutionalization: a 1-year prospective population-based study. | Bourdel-Marchasson I, Vincent S, Germain C, Salles N, Jenn J, Rasoamanarivo E, Emeriau JP, Rainfray M, Richard-Harston S | The journals of gerontology. Series A, Biological sciences and medical sciences | 2004 |
Aged, Aged, 80 and over, Delirium, diagnosis, Female, Geriatric Assessment, Humans, Incidence, Institutionalization, statistics & numerical data, Logistic Models, Male, Nutritional Status, Predictive Value of Tests, Prevalence, Prospective Studies, Risk Factors, Statistics, Nonparametric |
| Delirium in the first days of acute stroke. | Caeiro L, Ferro JM, Albuquerque R, Figueira ML | Journal of neurology | 2004 |
Acute Disease, Adult, Age Factors, Aged, Aged, 80 and over, Brain Stem Infarctions, complications, Causality, Cerebral Hemorrhage, complications, Cerebral Infarction, complications, Coronary Disease, complications, Delirium, etiology, Female, Humans, Male, Metabolic Diseases, complications, Middle Aged, Perceptual Disorders, complications, Prospective Studies, Stroke, complications |
| Delirium. | Henderson AS | International psychogeriatrics / IPA | 1991 |
Aged, Delirium, diagnosis, Diagnosis, Differential, Hospitalization, Humans, Risk Factors |
| Delirium in acute stroke: a preliminary study of the role of anticholinergic medications. | Caeiro L, Ferro JM, Claro MI, Coelho J, Albuquerque R, Figueira ML | European journal of neurology : the official journal of the European Federation of Neurological Societies | 2004 |
Aged, Aged, 80 and over, Analysis of Variance, Case-Control Studies, Cerebral Hemorrhage, complications, Cholinergic Antagonists, therapeutic use, Delirium, drug therapy, Female, Humans, Male, Regression Analysis, Retrospective Studies, Stroke, complications, Treatment Outcome |
| Delirium in elderly patients. | Cole MG | The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry | 2004 |
Acute Disease, Aged, Consciousness Disorders, diagnosis, Delirium, diagnosis, Diagnostic and Statistical Manual of Mental Disorders, Humans, Incidence, Language Disorders, diagnosis, Mood Disorders, diagnosis, Prevalence, Risk Factors, Sleep Disorders, diagnosis, Social Support, Wakefulness |
| Bioelectrical impedance analysis and other hydration parameters as risk factors for delirium in rural nursing home residents. | Culp KR, Wakefield B, Dyck MJ, Cacchione PZ, DeCrane S, Decker S | The journals of gerontology. Series A, Biological sciences and medical sciences | 2004 |
Aged, Dehydration, diagnosis, Delirium, diagnosis, Electric Impedance, Female, Humans, Long-Term Care, Male, Nursing Homes, Risk Factors, Rural Health Services |
| Changes in mental status. | Curtin AJ | Journal of the American Podiatric Medical Association | 2004 |
Aged, Delirium, diagnosis, Dementia, diagnosis, Diagnosis, Differential, Geriatric Assessment, Hospitalization, Humans, Podiatry, methods |
| Adding rivastigmine to antipsychotics in the treatment of a chronic delirium. | Dautzenberg PL, Mulder LJ, Olde Rikkert MG, Wouters CJ, Loonen AJ | Age and ageing | 2004 |
Aged, Aged, 80 and over, Antipsychotic Agents, administration & dosage, Cholinesterase Inhibitors, administration & dosage, Chronic Disease, Delirium, drug therapy, Drug Therapy, Combination, Female, Hospitalization, Humans, Male, Phenylcarbamates, administration & dosage, Retrospective Studies |
| Delirium: behavioural changes before and during the prodromal phase. | Duppils GS, Wikblad K | Journal of clinical nursing | 2004 |
Aged, Aged, 80 and over, Anxiety, classification, Arthroplasty, Replacement, Hip, adverse effects, Case-Control Studies, Chi-Square Distribution, Cognition Disorders, classification, Delirium, classification, Disease Progression, Female, Geriatric Assessment, Hip Fractures, complications, Humans, Male, Mental Disorders, classification, Mental Status Schedule, Prospective Studies, Risk Factors, Severity of Illness Index, Statistics, Nonparametric, Time Factors |
| Cognitive function and health-related quality of life after delirium in connection with hip surgery. A six-month follow-up. | Duppils GS, Wikblad K | Orthopedic nursing | 2004 |
Activities of Daily Living, Aged, Aged, 80 and over, Arthroplasty, Replacement, Hip, adverse effects, Cognition, Counseling, Delirium, diagnosis, Disease Progression, Family, psychology, Follow-Up Studies, Geriatric Assessment, Health Status, Humans, Mass Screening, Mental Status Schedule, Needs Assessment, Nurse’s Role, Nursing Assessment, Perioperative Care, methods, Quality of Life, Risk Factors, Sweden, epidemiology |
| Evaluation of functional improvement in older patients with cognitive impairment, depression and/or delirium admitted to a geriatric convalescence hospitalization unit. | Esperanza A, Miralles R, Rius I, Fernandez B, Digón A, Arranz P, Gonzalez P, Raja Y, Serrano P, Zafra M, Vazquez O, Gili P, Cervera AM | Archives of gerontology and geriatrics. Supplement | 2004 |
Aged, Cognition Disorders, diagnosis, Comorbidity, Convalescence, Delirium, epidemiology, Depression, epidemiology, Female, Health Services for the Aged, utilization, Health Status, Hospitalization, statistics & numerical data, Humans, Institutionalization, statistics & numerical data, Male, Neuropsychological Tests, Outcome Assessment (Health Care), Patient Discharge, statistics & numerical data, Prevalence, Severity of Illness Index |
| Delirium in palliative care. | Friedlander MM, Brayman Y, Breitbart WS | Oncology (Williston Park, N.Y.) | 2004 |
Antidepressive Agents, therapeutic use, Antipsychotic Agents, therapeutic use, Bipolar Disorder, diagnosis, Delirium, diagnosis, Dementia, diagnosis, Depression, diagnosis, Diagnosis, Differential, Humans, Neoplasms, complications, Palliative Care, methods, Severity of Illness Index, Terminally Ill |
| Dehydration and delirium--not a simple relationship. | George J, Rockwood K | The journals of gerontology. Series A, Biological sciences and medical sciences | 2004 |
Aged, Dehydration, physiopathology, Delirium, etiology, Humans |
| Instrument for detection of delirium in general hospitals: adaptation of the confusion assessment method. | González M, de Pablo J, Fuente E, Valdés M, Peri JM, Nomdedeu M, Matrai S | Psychosomatics | 2004 |
Adaptation, Psychological, Adolescent, Adult, Aged, Confusion, diagnosis, Delirium, diagnosis, Female, Hospitals, General, Humans, Male, Mass Screening, methods, Middle Aged, Questionnaires, Sensitivity and Specificity |
| A double-blind trial of risperidone and haloperidol for the treatment of delirium. | Han CS, Kim YK | Psychosomatics | 2004 |
Aged, Analysis of Variance, Antipsychotic Agents, therapeutic use, Delirium, drug therapy, Dose-Response Relationship, Drug, Double-Blind Method, Female, Haloperidol, therapeutic use, Humans, Male, Psychiatric Status Rating Scales, Risperidone, therapeutic use, Severity of Illness Index, Time Factors, Treatment Outcome |
| Delirium in the acute care setting. | Hanley C | Medsurg nursing : official journal of the Academy of Medical-Surgical Nurses | 2004 |
Aged, Delirium, diagnosis, Dementia, diagnosis, Depression, diagnosis, Diagnosis, Differential, Humans, Nursing Care, Patient Care, methods |
| A practical program for preventing delirium in hospitalized elderly patients. | Inouye SK | Cleveland Clinic journal of medicine | 2004 |
Aged, psychology, Delirium, etiology, Female, Humans, Inpatients, psychology, Risk Factors |
| Low incidence of delirium in very old patients after surgery for hip fractures. | Kagansky N, Rimon E, Naor S, Dvornikov E, Cojocaru L, Levy S | The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry | 2004 |
Aged, Aged, 80 and over, Cognition Disorders, diagnosis, Cohort Studies, Delirium, epidemiology, Demography, Female, Hip Fractures, surgery, Humans, Incidence, Male, Postoperative Period, Prospective Studies, Questionnaires, Socioeconomic Factors |