What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Reinforcement learning model for optimizing dexmedetomidine dosing to prevent delirium in critically ill patients
- Authors
- Lee, H. Y. Chung, S. Hyeon, D. Yang, H. L. Lee, H. C. Ryu, H. G. Lee, H.
- Year
- 2024
- Journal
- NPJ Digit Med
- Abstract
Delirium can result in undesirable outcomes including increased length of stays and mortality in patients admitted to the intensive care unit (ICU). Dexmedetomidine has emerged for delirium prevention in these patients; however, optimal dosing is challenging. A reinforcement learning-based Artificial Intelligence model for Delirium prevention (AID) is proposed to optimize dexmedetomidine dosing. The model was developed and internally validated using 2416 patients (2531 ICU admissions) and externally validated on 270 patients (274 ICU admissions). The estimated performance return of the AID policy was higher than that of the clinicians’ policy in both derivation (0.390 95% confidence interval [CI] 0.361 to 0.420 vs. -0.051 95% CI -0.077 to -0.025) and external validation (0.186 95% CI 0.139 to 0.236 vs. -0.436 95% CI -0.474 to -0.402) cohorts. Our finding indicates that AID might support clinicians’ decision-making regarding dexmedetomidine dosing to prevent delirium in ICU patients, but further off-policy evaluation is required.
- PMID
PMID: 39557970
PMCID: PMC11574043
- Keywords
Delirium
ICU
Dexmedetomidine
Artificial Intelligence model for Delirium prevention
- Page(s)
- Volume
- Issue
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| The effect of ketamine on emergence agitation in children: A systematic review and meta-analysis | Ng, K. T. Sarode, D. Lai, Y. S. Teoh, W. Y. Wang, C. Y. | Paediatr Anaesth | 2019 |
emergence agitation |
| BIS index monitoring and perioperative neurocognitive disorders in older adults: a systematic review and meta-analysis | Miao, M. Xu, Y. Sun, M. Chang, E. Cong, X. Zhang, J. | Aging Clin Exp Res | 2019 |
Bispectral index |
| Plasma biomarkers of inflammation, coagulation, and brain injury as predictors of delirium duration in older hospitalized patients | McNeil, J. B. Hughes, C. G. Girard, T. Ware, L. B. Ely, E. W. Chandrasekhar, R. Han, J. H. | PLoS One | 2019 | |
| Randomized controlled trial of acupuncture to prevent emergence delirium in children undergoing myringotomy tube placement | Martin, C. S. Yanez, N. D. Treggiari, M. M. Piper, L. Cusick, J. Lalwani, K. | Minerva Anestesiol | 2019 | |
| Detecting delirium in patients with acute stroke: a systematic review of test accuracy | Mansutti, I. Saiani, L. Palese, A. | BMC Neurol | 2019 |
Instruments |
| Associations of 4AT with mobility, length of stay and mortality in hospital and discharge destination among patients admitted with hip fractures | Lisk, R. Yeong, K. Enwere, P. Jenkinson, J. Robin, J. Irvin-Sellers, M. Fluck, D. Osmani, A. Sharmin, R. Sharma, P. Fry, C. H. Han, T. S. | Age Ageing | 2019 |
Nhs |
| Effectiveness of an advanced practice nurse-led delirium education and training programme | Lieow, J. L. M. Chen, F. S. M. Song, G. Tang, P. S. Kowitlawakul, Y. Mukhopadhyay, A. | Int Nurs Rev | 2019 |
Advanced Practice Nurses |
| Comparison of emergence agitation between succinylcholine and rocuronium-sugammadex in adults following closed reduction of a nasal bone fracture: A prospective randomized controlled trial | Lee, S. J. Sung, T. Y. Cho, C. K. | BMC Anesthesiology | 2019 |
adult |
| Risk factors for post-intensive care syndrome: A systematic review and meta-analysis | Lee, M. Kang, J. Jeong, Y. J. | Aust Crit Care | 2019 |
Intensive care units |
| Effect of Perioperative Low-Dose Dexmedetomidine on Postoperative Delirium After Living-Donor Liver Transplantation: A Randomized Controlled Trial | Lee, H. Yang, S. M. Chung, J. Oh, H. W. Yi, N. J. Suh, K. S. Oh, S. Y. Ryu, H. G. | Transplant Proc | 2019 | |
| The Association of Perioperative Serum Lactate Levels with Postoperative Delirium in Elderly Trauma Patients | Lee, C. Lee, J. Cho, H. Song, J. Jung, H. Ma, X. Hwang, J. | BioMed Research International | 2019 |
lactic acid |
| Frailty defined by 19 items as a predictor of short-term functional recovery in patients with hip fracture | Inoue, T. Misu, S. Tanaka, T. Kakehi, T. Kakiuchi, M. Chuman, Y. Ono, R. | Injury | 2019 |
aged |
| Using language descriptors to recognise delirium: a survey of clinicians and medical coders to identify delirium-suggestive words | Holmes, N. E. Amjad, S. Young, M. Berlowitz, D. J. Bellomo, R. | Crit Care Resusc | 2019 |
*Clinical Coding |
| Diagnostic test accuracy meta-analysis of PRE-DELIRIC (PREdiction of DELIRium in ICu patients): A delirium prediction model in intensive care practice | Ho, M. H. Chen, K. H. Montayre, J. Liu, M. F. Chang, C. C. Traynor, V. Shen Hsiao, S. T. Chang, H. R. Chiu, H. Y. | Intensive Crit Care Nurs | 2019 |
Delirium |
| Delirium management: Let's get physical? A systematic review and meta-analysis | Haley, M. N. Casey, P. Kane, R. Y. Darzins, P. Lawler, K. | Australas J Ageing | 2019 |
delirium |
| Delirium post-cardiac surgery: Incidence and associated factors | Habeeb-Allah, A. Alshraideh, J. A. | Nurs Crit Care | 2019 |
associated factors |
| EEG Correlates of Delirium in Children and Young Adults With CD19-Directed CAR T Cell Treatment-Related Neurotoxicity | Gust, J. Annesley, C. E. Gardner, R. A. Bozarth, X. | J Clin Neurophysiol | 2019 | |
| Process of implementing and delivering the Prevention of Delirium system of care: a mixed method preliminary study | Godfrey, M. Green, J. Smith, J. Cheater, F. Inouye, S. K. Hurst, K. Young, J. | BMC Geriatr | 2019 |
Delirium prevention |
| Association between postoperative delirium and postoperative cerebral oxygen desaturation in older patients after cardiac surgery | Eertmans, W. De Deyne, C. Genbrugge, C. Marcus, B. Bouneb, S. Beran, M. Fret, T. Gutermann, H. Boer, W. Vander Laenen, M. Heylen, R. Mesotten, D. Vanelderen, P. Jans, F. | Br J Anaesth | 2019 |
cardiac surgery |
| Frailty and hospital outcomes within a low socioeconomic population | Clark, S. Shaw, C. Padayachee, A. Howard, S. Hay, K. Frakking, T. T. | QJM | 2019 | |
| Perioperative outcomes in geriatric patients undergoing hip fracture surgery with different anesthesia techniques: A systematic review and meta-analysis | Chen, D. X. Yang, L. Ding, L. Li, S. Y. Qi, Y. N. Li, Q. | Medicine | 2019 |
Aged |
| Postoperative delirium is associated with increased plasma neurofilament light | Casey, C. P. Lindroth, H. Mohanty, R. Farahbakhsh, Z. Ballweg, T. Twadell, S. Miller, S. Krause, B. Prabhakaran, V. Blennow, K. Zetterberg, H. Sanders, R. D. | Brain | 2019 |
adult |
| Differential clinical characteristics, management and outcome of delirium among ward compared with intensive care unit patients | Canet, E. Amjad, S. Robbins, R. Lewis, J. Matalanis, M. Jones, D. Bellomo, R. | Intern Med J | 2019 |
*agitation |
| An Evaluation of Risperidone Dosing for Pediatric Delirium in Children Less Than or Equal to 2 Years of Age | Campbell, C. T. Grey, E. Munoz-Pareja, J. Manasco, K. B. | Annals of Pharmacotherapy | 2019 |
article |
| Inpatient Rehabilitation Delirium Screening: Impact on Acute Care Transfers and Functional Outcomes | Bushi, S. Barrett, A. M. Oh-Park, M. | PMR | 2019 |
Acute Care Transfer |
| Routine Management of Postoperative Delirium Outside the ICU: Results of an International Survey among Anaesthesiologists | Bilotta, F. Weiss, B. Neuner, B. Kramer, S. Aldecoa, C. Bettelli, G. Sanders, R. D. Delp, S. M. Spies, C. D. | Acta Anaesthesiol Scand | 2019 |
Postoperative delirium |
| Impact of delirium on short-term outcomes in hip fracture patients under a program of approach to delirium | Bielza, R. Zambrana, F. Fernandez de la Puente, E. Sanjurjo, J. Andreu, C. Thuissard, I. J. Gomez Cerezo, J. | Geriatr Gerontol Int | 2019 |
delirium |
| Outcome Differences by Delirium Motor Subtype in Patients with Ischemic Stroke | Yang, H. W. Lee, M. Shin, J. W. Jeong, H. S. Kim, J. Kim, J. L. | Psychiatry Investig | 2019 |
Delirium |
| Serial Ottawa 3DY assessments to detect delirium in older emergency department community dwellers | Yadav, K. Boucher, V. Carmichael, P. H. Voyer, P. Eagles, D. Pelletier, M. Gouin, E. Daoust, R. Vu, T. T. M. Berthelot, S. Emond, M. | Age Ageing | 2019 |
delirium |
| Development and validation of a postoperative delirium prediction model for patients admitted to an intensive care unit in China: a prospective study | Xing, H. Zhou, W. Fan, Y. Wen, T. Wang, X. Chang, G. | BMJ Open | 2019 |
delirium |
| Acute kidney injury as a risk factor of hyperactive delirium: A case control study | Wan, R. McKenzie, C. A. Taylor, D. Camporota, L. Ostermann, M. | J Crit Care | 2019 |
Acute kidney injury |
| The Effect of Frailty on Outcome After Vascular Surgery | Visser, L. Banning, L. B. D. El Moumni, M. Zeebregts, C. J. Pol, R. A. | European Journal of Vascular and Endovascular Surgery | 2019 |
adverse outcome |
| Apolipoprotein E genotype and the association between C-reactive protein and postoperative delirium: Importance of gene-protein interactions | Vasunilashorn, S. M. Ngo, L. H. Inouye, S. K. Fong, T. G. Jones, R. N. Dillon, S. T. Libermann, T. A. O'Connor, M. Arnold, S. E. Xie, Z. Marcantonio, E. R. | Alzheimers Dement | 2019 |
Apolipoprotein E |
| In-hospital outcomes and 30-day readmission rates among ischemic and hemorrhagic stroke patients with delirium | Vahidy, F. S. Bambhroliya, A. B. Meeks, J. R. Rahman, O. Ely, E. W. Slooter, A. J. C. Tyson, J. E. Miller, C. C. McCullough, L. D. Savitz, S. I. Khan, B. | PLoS One | 2019 | |
| Reducing delirium and cognitive dysfunction after off-pump coronary bypass: A randomized trial | Szwed, K. Pawliszak, W. Szwed, M. Tomaszewska, M. Anisimowicz, L. Borkowska, A. | Journal of Thoracic and Cardiovascular Surgery | 2019 |
adult |
| A randomized control trial comparing prophylactic dexmedetomidine versus clonidine on rates and duration of delirium in older adult patients undergoing coronary artery bypass grafting | Shokri, H. Ali, I. | Journal of Clinical Anesthesia | 2019 |
adult |
| Predisposing and precipitating risk factors for delirium in palliative care patients | Seiler, A. Schubert, M. Hertler, C. Schettle, M. Blum, D. Guckenberger, M. Weller, M. Ernst, J. von Kanel, R. Boettger, S. | Palliat Support Care | 2019 |
Delirium |
| Preventive effect of dexmedetomidine on postictal delirium after electroconvulsive therapy: A randomised controlled study | Qiu, Z. Zhou, S. Zhang, M. Guo, N. Huang, P. Xiang, P. Hei, Z. Li, X. | Eur J Anaesthesiol | 2019 | |
| Activity-based occupational therapy intervention for delirium superimposed on dementia in nursing home setting: a feasibility study | Pozzi, C. Lanzoni, A. Lucchi, E. Salimbeni, I. DeVreese, L. P. Bellelli, G. Fabbo, A. Morandi, A. | Aging Clin Exp Res | 2019 |
Delirium |
| Trials Focusing on Prevention and Treatment of Delirium After Cardiac Surgery: A systematic Review of Randomized Evidence | Pieri, M. De Simone, A. Rose, S. De Domenico, P. Lembo, R. Denaro, G. Landoni, G. Monaco, F. | Journal of Cardiothoracic and Vascular Anesthesia | 2019 |
adult |
| Association of comt val158met polymorphism with delirium risk and outcomes after traumatic brain injury | Nekrosius, D. Kaminskaite, M. Jokubka, R. Pranckeviciene, A. Lideikis, K. Tamasauskas, A. Bunevicius, A. | Journal of Neuropsychiatry and Clinical Neurosciences | 2019 |
methionine |
| Anticholinergic burden of long-term medication is an independent risk factor for the development of postoperative delirium: A clinical trial | Mueller, A. Spies, C. D. Eckardt, R. Weiss, B. Pohrt, A. Wernecke, K. D. Schmidt, M. | Journal of Clinical Anesthesia | 2019 |
aged |
| Renal function and delirium in older fracture patients: different information from different formulas? | Mossello, E. Rivasi, G. Tortu, V. Giordano, A. Iacomelli, I. Cavallini, M. C. Rafanelli, M. Ceccofiglio, A. Cartei, A. Rostagno, C. Bari, M. D. Ungar, A. | Eur J Intern Med | 2019 |
Creatinine |
| Reversibility of delirium in Ill-hospitalized cancer patients: Does underlying etiology matter? | Matsuda, Y. Maeda, I. Morita, T. Yamauchi, T. Sakashita, A. Watanabe, H. Kaneishi, K. Amano, K. Iwase, S. Ogawa, A. Yoshiuchi, K. | Cancer Med | 2019 |
cancer |
| Association Between Perioperative Hypotension and Delirium in Postoperative Critically Ill Patients: A Retrospective Cohort Analysis | Maheshwari, K. Ahuja, S. Khanna, A. K. Mao, G. Perez-Protto, S. Farag, E. Turan, A. Kurz, A. Sessler, D. I. | Anesth Analg | 2019 | |
| A short delirium caregiver questionnaire for triage of elderly outpatients with cognitive impairment: a development and test accuracy study | Luijendijk, H. J. Quispel-Aggenbach, D. W. P. Stroomer-van Wijk, A. J. M. Meijerink-Blom, A. H. van Walbeek, A. Zuidema, S. U. | International Psychogeriatrics | 2019 |
aged |
| Intraoperative Oxidative Damage and Delirium after Cardiac Surgery | Lopez, M. G. Hughes, C. G. DeMatteo, A. O'Neal, J. B. McNeil, J. B. Shotwell, M. S. Morse, J. Petracek, M. R. Shah, A. S. Brown, N. J. Billings, F. T. th | Anesthesiology | 2019 | |
| Postoperative delirium after hip surgery is a potential risk factor for incident dementia: A systematic review and meta-analysis of prospective studies | Lee, S. J. Jung, S. H. Lee, S. U. Lim, J. Y. Yoon, K. S. Lee, S. Y. | Arch Gerontol Geriatr | 2019 |
Delirium |
| Evaluation of emergency department derived delirium prediction models using a hospital-wide cohort | Lee, S. Harland, K. Mohr, N. M. Matthews, G. Hess, E. P. Bellolio, M. F. Han, J. H. Weckmann, M. Carnahan, R. | Journal of Psychosomatic Research | 2019 |
aged |
| The Practical Use of White Cell Inflammatory Biomarkers in Prediction of Postoperative Delirium after Cardiac Surgery | Kotfis, K. Slozowska, J. Safranow, K. Szylinska, A. Listewnik, M. | Brain Sci | 2019 |
Nlr |
| Characteristics, risk factors and outcome of early-onset delirium in elderly patients with first ever acute ischemic stroke-A prospective observational cohort study | Kotfis, K. Bott-Olejnik, M. Szylińska, A. Listewnik, M. Rotter, I. | Clinical Interventions in Aging | 2019 |
NCT03944694 |
| Biomarkers of Delirium Duration and Delirium Severity in the ICU | Khan, B. A. Perkins, A. J. Prasad, N. K. Shekhar, A. Campbell, N. L. Gao, S. Wang, S. Khan, S. H. Marcantonio, E. R. Twigg, H. L., 3rd Boustani, M. A. | Crit Care Med | 2019 | |
| The Role of Inflammation after Surgery for Elders (RISE) study: Study design, procedures, and cohort profile | Hshieh, T. T. Vasunilashorn, S. M. D'Aquila, M. L. Arnold, S. E. Dickerson, B. C. Fong, T. G. Jones, R. N. Marcantonio, E. R. Schmitt, E. M. Xu, G. Gou, Y. Chen, F. Kunze, L. J. Vlassakov, K. V. Abdeen, A. R. Lange, J. K. Earp, B. E. Touroutoglou, A. Carl | Alzheimers Dement | 2019 |
Biomarkers |
| Clock Drawing Performance Slows for Older Adults after Total Knee Replacement Surgery | Hizel, L. P. Warner, E. D. Wiggins, M. E. Tanner, J. J. Parvataneni, H. Davis, R. Penney, D. L. Libon, D. J. Tighe, P. Garvan, C. W. Price, C. C. | Anesthesia and Analgesia | 2019 |
nct01786577 |
| Postoperative delirium after lung resection for primary lung cancer: Risk factors, risk scoring system, and prognosis | Hayashi, K. Motoishi, M. Sawai, S. Horimoto, K. Hanaoka, J. | PLoS One | 2019 | |
| Intraoperative Low Alpha Power in the Electroencephalogram Is Associated With Postoperative Subsyndromal Delirium | Gutierrez, R. Egaña, J. I. Saez, I. Reyes, F. Briceño, C. Venegas, M. Lavado, I. Penna, A. | Frontiers in Systems Neuroscience | 2019 |
electroencephalograph |
| Post-operative delirium associated with metabolic alterations following hemi-arthroplasty in older patients | Guo, Y. Li, Y. Zhang, Y. Fang, S. Xu, X. Zhao, A. Zhang, J. Li, J. V. Ma, D. Jia, W. Jiang, W. | Age Ageing | 2019 |
hip fracture |
| Validation of the Delirium Diagnostic Tool-Provisional (DDT-Pro) With Medical Inpatients and Comparison With the Confusion Assessment Method Algorithm | Franco, J. G. Ocampo, M. V. Velásquez-Tirado, J. D. Zaraza, D. R. Giraldo, A. M. Serna, P. A. López, C. Zuluaga, A. Sepúlveda, E. Kean, J. Trzepacz, P. T. | Journal of Neuropsychiatry and Clinical Neurosciences | 2019 |
administrative personnel |
| Efficacy and safety of haloperidol for delirium prevention in adult patients: An updated meta-analysis with trial sequential analysis of randomized controlled trials | Chen, Z. Chen, R. Zheng, D. Su, Y. Wen, S. Guo, H. Ye, Z. Deng, Y. Liu, G. Zuo, L. Wei, X. Hou, Y. | Journal of Clinical Anesthesia | 2019 |
adult |
| Change in Serum Level of Interleukin 6 and Delirium After Coronary Artery Bypass Graft | Chen, Y. Lu, S. Wu, Y. Shen, Y. Zhao, H. Ding, S. Feng, X. Sun, L. Tao, X. Li, J. Ma, R. Liu, W. Wu, F. Feng, Y. | Am J Crit Care | 2019 | |
| Preoperative cardiac function parameters as valuable predictors for nurses to recognise delirium after cardiac surgery: a prospective cohort study | Cai, S. Latour, J. M. Lin, Y. Pan, W. Zheng, J. Xue, Y. Gao, J. Lv, M. Zhang, X. Luo, Z. Wang, C. Zhang, Y. | Eur J Cardiovasc Nurs | 2019 |
Cardiac surgery |
| Bedside mental status and outcome in elderly patients admitted for acute coronary syndromes | Briet, C. Blanchart, K. Lemaitre, A. Roux, I. Lavergne, K. Rocamora, A. Bignon, M. Ardouin, P. Sabatier, R. Roule, V. Beygui, F. | Heart | 2019 |
acute coronary syndrome |
| Delirium Screening in Aphasic Patients With the Intensive Care Delirium Screening Checklist (ICDSC): A Prospective Cohort Study | Bosselmann, C. Zurloh, J. Stefanou, M. I. Stadler, V. Weber, Y. Lerche, H. Poli, S. Ziemann, U. Mengel, A. | Front Neurol | 2019 |
intensive care delirium screening checklist |
| Impact of Frailty on 30-Day Morbidity and Mortality of Patients With Intertrochanteric Femur Fractures | Boissonneault, A. Mener, A. Schwartz, A. Wilson, J. Staley, C. Schenker, M. | Orthopedics | 2019 | |
| The utility of nursing instruments for daily screening for delirium: Delirium causes substantial functional impairment | Bode, L. Isler, F. Fuchs, S. Marquetand, J. Petry, H. Ernst, J. Schubert, M. Garcia Nunez, D. von Kanel, R. Boettger, S. | Palliat Support Care | 2019 |
Assessment |
| The short IQCODE as a predictor for delirium in hospitalized geriatric patients | Blandfort, S. Gregersen, M. Rahbek, K. Juul, S. Damsgaard, E. M. | Aging Clin Exp Res | 2019 |
Delirium predictor |
| The relationship among frailty, delirium and attentional tests to detect delirium: a cohort study | Bellelli, P. G. Biotto, M. Morandi, A. Meagher, D. Cesari, M. Mazzola, P. Annoni, G. Zambon, A. | Eur J Intern Med | 2019 |
Attention |
| Haloperidol for the treatment of delirium in critically ill patients: A systematic review with meta-analysis and Trial Sequential Analysis | Barbateskovic, M. Krauss, S. R. Collet, M. O. Andersen-Ranberg, N. C. Mathiesen, O. Jakobsen, J. C. Perner, A. Wetterslev, J. | Acta Anaesthesiologica Scandinavica | 2019 |
adult |
| The Volunteer Dementia and Delirium Care (VDDC) © Program: An Exploration of Perceived Barriers and Enablers to Implementation in an Acute and Subacute Metropolitan Hospital | Ayton, D. Moran, C. Berkovic, D. Bateman, C. Anderson, K. Blair, A. Soh, S. E. Morello, R. Ying Lim, Y. Liew, D. | Australas J Ageing | 2019 |
delirium |
| Comorbidities rather than age affect medium-term outcome in octogenarian patients after total knee arthroplasty | Andreozzi, V. Conteduca, F. Iorio, R. Di Stasio, E. Mazza, D. Drogo, P. Annibaldi, A. Ferretti, A. | Knee Surg Sports Traumatol Arthrosc | 2019 |
Comorbidity |
| Effect of the Tailored, Family-Involved Hospital Elder Life Program on Postoperative Delirium and Function in Older Adults: A Randomized Clinical Trial | Wang, Y. Y. Yue, J. R. Xie, D. M. Carter, P. Li, Q. L. Gartaganis, S. L. Chen, J. Inouye, S. K. | JAMA Intern Med | 2019 | |
| Nomogram for Predicting Postoperative Delirium After Deep Brain Stimulation Surgery for Parkinson's Disease | Wang, X. Q. Zhuang, H. X. Zhang, L. X. Chen, X. Niu, C. S. Zhao, M. | World Neurosurg | 2019 |
Deep brain stimulation |
| Automated tracking of level of consciousness and delirium in critical illness using deep learning | Sun, H. Kimchi, E. Akeju, O. Nagaraj, S. B. McClain, L. M. Zhou, D. W. Boyle, E. Zheng, W. L. Ge, W. Westover, M. B. | NPJ Digital Medicine | 2019 |
propofol |
| Impact of natural light exposure on delirium burden in adult patients receiving invasive mechanical ventilation in the ICU: a prospective study | Smonig, R. Magalhaes, E. Bouadma, L. Andremont, O. de Montmollin, E. Essardy, F. Mourvillier, B. Lebut, J. Dupuis, C. Neuville, M. Lermuzeaux, M. Timsit, J. F. Sonneville, R. | Ann Intensive Care | 2019 |
Agitation |
| Differences in 90-day mortality of delirium subtypes in the intensive care unit: A retrospective cohort study | Rood, P. J. T. van de Schoor, F. van Tertholen, K. Pickkers, P. van den Boogaard, M. | J Crit Care | 2019 |
Critical care |
| The Role of Delirium and Other Risk Factors on Mortality in Elderly Patients with Critical Limb Ischemia Undergoing Major Lower Limb Amputation | Roijers, J. P. Hopmans, C. J. Janssen, T. L. Mulder, P. G. H. Buimer, M. G. Ho, G. H. de Groot, H. G. W. Veen, E. J. van der Laan, L. | Ann Vasc Surg | 2019 | |
| Antipsychotics for preventing delirium in hospitalized adults a systematic review | Oh, E. S. Needham, D. M. Nikooie, R. Wilson, L. M. Zhang, A. Robinson, K. A. Neufeld, K. J. | Annals of Internal Medicine | 2019 |
neuroleptic agent |
| Antipsychotics for treating delirium in hospitalized adults a systematic review | Nikooie, R. Neufeld, K. J. Oh, E. S. Wilson, L. M. Zhang, A. Robinson, K. A. Needham, D. M. | Annals of Internal Medicine | 2019 |
amisulpride |
| Exploiting Machine Learning Algorithms and Methods for the Prediction of Agitated Delirium After Cardiac Surgery: Models Development and Validation Study | Mufti, H. N. Hirsch, G. M. Abidi, S. R. Abidi, S. S. R. | JMIR Med Inform | 2019 |
cardiac surgery |
| Predictors and prognosis of delirium among older subjects in cardiac intensive care unit: focus on potentially preventable forms | Mossello, E. Baroncini, C. Pecorella, L. Giulietti, C. Chiti, M. Caldi, F. Cavallini, M. C. Simoni, D. Baldasseroni, S. Fumagalli, S. Valoti, P. Stroppa, S. Parenti, K. Ungar, A. Masotti, G. Marchionni, N. Di Bari, M. | Eur Heart J Acute Cardiovasc Care | 2019 |
*Delirium |
| Dysfunction of the blood-brain barrier in postoperative delirium patients, referring to the axonal damage biomarker phosphorylated neurofilament heavy subunit | Mietani, K. Sumitani, M. Ogata, T. Shimojo, N. Inoue, R. Abe, H. Kawamura, G. Yamada, Y. | PLoS One | 2019 | |
| The 4 ‘a’s test for detecting delirium in acute medical patients: A diagnostic accuracy study | Maclullich, A. M. J. Shenkin, S. D. Goodacre, S. Godfrey, M. Hanley, J. Stíobhairt, A. Lavender, E. Boyd, J. Stephen, J. Weir, C. Macraild, A. Steven, J. Black, P. Diernberger, K. Hall, P. Tieges, Z. Fox, C. Anand, A. Young, J. Siddiqi, N. Gray, A. | Health Technology Assessment | 2019 |
ISRCTN53388093 |
| Initiation and continuation of antipsychotic medicines in older people following non-psychiatric hospital admission | Kalisch Ellett, L. M. Pratt, N. L. Apajee, J. Roughead, E. E. | Int J Clin Pharm | 2019 |
Antipsychotic |
| Staged Implementation of Awakening and Breathing, Coordination, Delirium Monitoring and Management, and Early Mobilization Bundle Improves Patient Outcomes and Reduces Hospital Costs | Hsieh, S. J. Otusanya, O. Gershengorn, H. B. Hope, A. A. Dayton, C. Levi, D. Garcia, M. Prince, D. Mills, M. Fein, D. Colman, S. Gong, M. N. | Critical Care Medicine | 2019 |
adult |
| The Prevalence of Delirium in An Older Acute Surgical Population and Its Effect on Outcome | Hewitt, J. Owen, S. Carter, B. R. Stechman, M. J. Tay, H. S. Greig, M. McCormack, C. Pearce, L. McCarthy, K. Myint, P. K. Moug, S. J. | Geriatrics | 2019 |
Cognitive impairment |
| Care challenges in older general hospital patients : Impact of cognitive impairment and other patient-related factors | Hendlmeier, I. Bickel, H. Hessler-Kaufmann, J. B. Schaufele, M. | Z Gerontol Geriatr | 2019 |
Adverse events |
| Efficacy of music on sedation, analgesia and delirium in critically ill patients. A systematic review of randomized controlled trials | Garcia Guerra, G. Almeida, L. Zorzela, L. King-Jones, S. Joffe, A. R. Hartling, L. Jou, H. Vohra, S. | J Crit Care | 2019 |
Analgesia |
| Postoperative Pressure Ulcers After Geriatric Hip Fracture Surgery Are Predicted by Defined Preoperative Comorbidities and Postoperative Complications | Galivanche, A. R. Kebaish, K. J. Adrados, M. Ottesen, T. D. Varthi, A. G. Rubin, L. E. Grauer, J. N. | The Journal of the American Academy of Orthopaedic Surgeons | 2019 |
adult |
| The Healthy Heart-Mind Trial: Randomized Controlled Trial of Melatonin for Prevention of Delirium | Ford, A. H. Flicker, L. Kelly, R. Patel, H. Passage, J. Wibrow, B. Anstey, M. Edwards, M. Almeida, O. P. | J Am Geriatr Soc | 2019 |
cardiothoracic |
| The Caregiver Burden of Delirium in Older Adults With Alzheimer Disease and Related Disorders | Fong, T. G. Racine, A. M. Fick, D. M. Tabloski, P. Gou, Y. Schmitt, E. M. Hshieh, T. T. Metzger, E. Bertrand, S. E. Marcantonio, E. R. Jones, R. N. Inouye, S. K. | J Am Geriatr Soc | 2019 |
Alzheimer disease |
| Geriatric Events Among Older Adults Undergoing Nonelective Surgery Are Associated with Poor Outcomes | Dworsky, J. Q. Childers, C. P. Copeland, T. Maggard-Gibbons, M. Tan, H. J. Saliba, D. Russell, M. M. | Am Surg | 2019 | |
| Shifting the focus: A QI project to improve the management of delirium in patients with hip fracture | Dormandy, L. Mufti, S. Higgins, E. Bailey, C. Dixon, M. | Future Healthc J | 2019 |
Neck of femur fracture |
| Impact of a delirium prevention project among older hospitalized patients who underwent orthopedic surgery: a retrospective cohort study | Choi, J. Y. Kim, K. I. Kang, M. G. Lee, Y. K. Koo, K. H. Oh, J. H. Park, Y. H. Suh, J. Kim, N. H. Yoo, H. J. Koo, J. Moon, H. M. Kim, E. H. Park, K. Kim, C. H. | BMC Geriatr | 2019 |
Delirium |
| Melatonin for the prevention of postoperative delirium in older adults: a systematic review and meta-analysis | Campbell, A. M. Axon, D. R. Martin, J. R. Slack, M. K. Mollon, L. Lee, J. K. | BMC Geriatr | 2019 |
Delirium |
| Assessment of a Geriatric Hip Fracture Program: Analysis of Harmful Adverse Events Using the Global Trigger Tool | Blood, T. D. Deren, M. E. Goodman, A. D. Hayda, R. A. Trafton, P. G. | Journal of Bone and Joint Surgery - American Volume | 2019 |
acute blood loss anemia |
| Clinical management of delirium: The response depends on the subtypes. An observational cohort study in 602 patients | Zipser, C. M. Knoepfel, S. Hayoz, P. Schubert, M. Ernst, J. von Kanel, R. Boettger, S. | Palliat Support Care | 2019 |
Antipsychotics |
| Predisposing and precipitating factors for delirium in neurology: a prospective cohort study of 1487 patients | Zipser, C. M. Deuel, J. Ernst, J. Schubert, M. Weller, M. von Kanel, R. Boettger, S. | J Neurol | 2019 |
Delirium |
| Risk factors for postoperative delirium after spinal surgery: a systematic review and meta-analysis | Zhu, C. Wang, B. Yin, J. Xue, Q. Gao, S. Xing, L. Wang, H. Liu, W. Liu, X. | Aging Clin Exp Res | 2019 |
Delirium |
| Dexmedetomidine for the prevention of postoperative delirium in elderly patients undergoing noncardiac surgery: A meta-analysis of randomized controlled trials | Zeng, H. Li, Z. He, J. Fu, W. | PLoS One | 2019 | |
| Risk factors for delirium: Are therapeutic interventions part of it? | Xing, J. Yuan, Z. Jie, Y. Liu, Y. Wang, M. Sun, Y. | Neuropsychiatric Disease and Treatment | 2019 |
arterial line |