What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Delirium as a Determinant of Long-Term Cognitive Dysfunction in the Context of Post-intensive Care Syndrome: A Prospective Study in a Latin American Environment
- Authors
- Mesa, P. Kotfis, K. Lecor, C. Leyes, C. Banchero, A. De Mattos, S. Somma, V. Orellano, M. Favretto, S. Barros, M.
- Year
- 2025
- Journal
- Cureus
- Abstract
Introduction Cognitive dysfunction represents a major healthcare concern in the 21st century. Prolonged cognitive dysfunction and concomitant psychological and physical disorders in patients admitted to the intensive care unit (ICU) are components of the post-ICU syndrome (PICS). Notwithstanding the numerous published studies in this area, our work is the first to explore the relationship between PICS and delirium in the ICU in Uruguay. This research underscores the significance and potential of our study, which we believe will make a substantial contribution to this field of research in Latin America. Objectives The incidence rates of the cognitive, psychological, and physical sequelae constituting PICS were evaluated, and the relationships between these disorders and delirium in the ICU were studied. Methods This was a prospective cohort study in which patients were followed up for one year after admission to the ICU of Hospital Pasteur between 03/01/2017 and 05/31/2017. The pre-ICU condition of each patient was considered in the analysis. An initial telephone interview was conducted using the following scales: the Hamilton scale was used to assess anxiety, the Pfeiffer scale was used to assess cognitive impairment, and the Barthel scale was used to assess activities of daily living (ADLs). In a second face-to-face interview, the Mini-Mental State Examination (MMSE) and the Beck Depression Scale II (BDS-II) were used. Results Forty-three patients were divided into two groups: 15 (34%) with delirium in the ICU and 28 (66%) without delirium. The association of delirium with different sequelae was evaluated using the corresponding scales: Pfeiffer scale: Cognitive impairment was observed in 7/13 patients (53%) in the delirium group vs. 0/29 patients (0%) in the non-delirious group (p 0.001); MMSE score: Deterioration was observed in 6/7 patients (86%) in the delirium group vs. 1/7 patients (14%) in the non-delirious group (p 0.007). Cognitive impairment was found in 3/6 patients (50%) who presented with delirium in the ICU, while 1/8 patients (13%) who did not present with delirium experienced cognitive impairment (p = 0.036); Hamilton scale: Anxiety was found in 8/15 patients (57%) in the delirium group and 20/29 patients (68%) in the non-delirious group; BDS-II: Depression was found in 12/12 patients (100%) in the delirium group vs. 27/29 patients (93%) in the non-delirious group (p 0.57). Barthel scale: Dependence on others for ADLs was observed in 3/15 patients (20%) in the delirium group vs. 4/29 patients (14%) in the non-delirious group (p = 0.23). Conclusions Cognitive impairment was observed to be associated with delirium in the ICU, opening new avenues for research and possible treatment options. Although dependence on activities of daily living (ADLs) was more common in the delirium group, the difference between the two groups was not significant, highlighting the need for further research to understand the whole picture. Rates of anxiety and depression after ICU stay were also similar between the two groups, providing a baseline for comparison and informing future studies. The study highlights the urgent need for delirium-specific interventions in the ICU to address cognitive dysfunction and improve long-term outcomes in critically ill patients.
- PMID
PMID: 40225547
PMCID: PMC11994226
- Keywords
cam-icu cognitive cognitive impairment delirium medical intensive care unit (micu) physical sequelae post intensive care psychological
- Page(s)
- Volume
- Issue
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| Neurocovid: Pharmacological Recommendations for Delirium Associated With COVID-19 | Baller, E. B. Hogan, C. S. Fusunyan, M. A. Ivkovic, A. Luccarelli, J. W. Madva, E. Nisavic, M. Praschan, N. Quijije, N. V. Beach, S. R. Smith, F. A. | Psychosomatics | 2020 |
Adrenergic alpha-2 Receptor Agonists/ therapeutic use |
| An Implementation Assessment of the Virtual Acute Care for Elders Program From the Perspective of Key Stakeholders | Balentine, C. J. Morris, M. Knight, S. J. Turan, J. M. Flood, K. L. Gutierrez-Meza, D. Macdonald, C. L. Bhatia, S. Brown, C. J. | Ann Surg | 2020 | |
| The 'third wave': impending cognitive and functional decline in COVID-19 survivors | Baker, H. A. Safavynia, S. A. Evered, L. A. | Br J Anaesth | 2020 |
Covid-19 |
| Presence of urinary symptoms in bacteremic urinary tract infection: a retrospective cohort study of Escherichia coli bacteremia | Bai, A. D. Bonares, M. J. Thrall, S. Bell, C. M. Morris, A. M. | BMC Infect Dis | 2020 |
Aged |
| Risk Factors of Postoperative Delirium in Older Adult Spine Surgery Patients: A Meta-Analysis | Baek, W. Kim, Y. M. Lee, H. | AORN J | 2020 |
delirium |
| Psychosocial volunteer support for older adults with cognitive impairment: development of MyCare Ageing using a codesign approach via action research | Ayton, D. O'Donnell, R. Vicary, D. Bateman, C. Moran, C. Srikanth, V. K. Lustig, J. Banaszak-Holl, J. Hunter, P. Pritchard, E. Morris, H. Savaglio, M. Parikh, S. Skouteris, H. | BMJ Open | 2020 |
dementia |
| The Volunteer Dementia and Delirium Care (VDDC)©: A pre-implementation study exploring perceived acceptability to implementing the program in an acute and subacute metropolitan hospital | Ayton, D. Moran, C. Berkovic, D. Bateman, C. Anderson, K. Blair, A. Soh, S. E. Morello, R. Lim, Y. Y. Liew, D. | Australas J Ageing | 2020 |
delirium |
| A call to action for delirium research: Meta-analysis and regression of delirium associated mortality | Aung Thein, M. Z. Pereira, J. V. Nitchingham, A. Caplan, G. A. | BMC Geriatr | 2020 |
Aged |
| Accuracy and Feasibility of Clinically Applied Frailty Instruments before Surgery: A Systematic Review and Meta-analysis | Aucoin, S. D. Hao, M. Sohi, R. Shaw, J. Bentov, I. Walker, D. McIsaac, D. I. | Anesthesiology | 2020 |
Aged |
| Could COVID delirium bring on dementia? | Arnold, C. | Nature | 2020 |
COVID-19/ complications/epidemiology/ psychology |
| Neighborhood-Level Social Disadvantage and Risk of Delirium Following Major Surgery | Arias, F. Chen, F. Fong, T. G. Shiff, H. Alegria, M. Marcantonio, E. R. Gou, Y. Jones, R. N. Travison, T. G. Schmitt, E. M. Kind, A. J. H. Inouye, S. K. | J Am Geriatr Soc | 2020 |
Area Deprivation Index |
| Delirium is independently associated with early mortality in elderly patients starting hemodialysis | Arai, Y. Shioji, S. Tanaka, H. Kondo, I. Sakamoto, E. Suzuki, M. Katagiri, D. Tada, M. Hinoshita, F. | Clin Exp Nephrol | 2020 |
Chronic kidney disease |
| COVID-19 inpatients with psychiatric disorders: Real-world clinical recommendations from an expert team in consultation-liaison psychiatry | Anmella, G. Arbelo, N. Fico, G. Murru, A. Llach, C. D. Madero, S. Gomes-da-Costa, S. Imaz, M. L. López-Pelayo, H. Vieta, E. Pintor, L. | J Affect Disord | 2020 |
Aged |
| Relationship Between Intensive Care Unit Delirium Severity and 2-Year Mortality and Health Care Utilization | Andrews, P. S. Wang, S. Perkins, A. J. Gao, S. Khan, S. Lindroth, H. Boustani, M. Khan, B. | American journal of critical care : an official publication, American Association of Critical-Care Nurses | 2020 |
adult |
| Impact of a Pharmacist-Led Intensive Care Unit Sleep Improvement Protocol on Sleep Duration and Quality | Andrews, J. L. Louzon, P. R. Torres, X. Pyles, E. Ali, M. H. Du, Y. Devlin, J. W. | Ann Pharmacother | 2020 |
activity tracker |
| A Case of Concurrent Delirium and Catatonia in a Woman With Coronavirus Disease 2019 | Amouri, J. Andrews, P. S. Heckers, S. Ely, E. W. Wilson, J. E. | Psychosomatics | 2020 | |
| Delirium pathway: a North Hampshire experience | Al-Rawi, Y. A. | Progress in Neurology and Psychiatry | 2020 |
aged |
| Incidence and risk factors for acute delirium in older patients with a hip fracture: A retrospective cohort study | Aldwikat, R. K. Manias, E. Nicholson, P. | Nurs Health Sci | 2020 |
hip fracture |
| Delirium, insulin-like growth factor I, growth hormone in older inpatients | Adamis, D. Coada, I. Eikelenboom, P. Chu, C. S. Finn, K. Melvin, V. Williams, J. Meagher, D. J. McCarthy, G. | World J Psychiatry | 2020 |
Cognition |
| Critical Review and Meta-Analysis of Postoperative Sedation after Adult Cardiac Surgery: Dexmedetomidine Versus Propofol | Abowali, H. A. Paganini, M. Enten, G. Elbadawi, A. Camporesi, E. M. | J Cardiothorac Vasc Anesth | 2020 |
adult open cardiac surgery |
| Polypharmacy at admission prolongs length of hospitalization in gastrointestinal surgery patients | Abe, N. Kakamu, T. Kumagai, T. Hidaka, T. Masuishi, Y. Endo, S. Kasuga, H. Fukushima, T. | Geriatr Gerontol Int | 2020 |
Adult |
| Stroke-related delirium | Al-Khaled, M. | Journal of the Neurological Sciences | 2021 |
article |
| Practice Variability in Screening and Treating Pediatric Critical Illness Delirium: Survey | Aljabari, S. Carter, C. Waheed, S. Anderson, J. E. | Journal of Pediatric Intensive Care | 2020 |
child |
| Perioperative complications of pediatric otorhinolaryngological operations | Aleksandrovich, Y. Rybianov, V. Pshenisnov, K. V. Razumov, S. | Saudi Journal of Anaesthesia | 2020 |
Complications ENT Heart rate variability Pediatric Perioperative |
| Prevention as Intervention: Reducing Incident Delirium in Heart Failure | Albert, B. L. | Journal of doctoral nursing practice | 2019 |
acute heart failure |
| The prevalence of prescribing medications associated with geriatric syndromes among discharged elderly patients | Akkawi, M. E. Taufek, N. H. M. Hadi, A. D. A. Nik Lah, N. N. N. F. | Journal of Pharmacy and Bioallied Sciences | 2020 |
Elderly patients Geriatric Syndromes Medication prescribing |
| Incidence and predictors of delirium after cardiac arrest – A retrospective registry | Aicher, N. Jäckel, M. Faye, C. Wengenmayer, T. Bode, C. Staudacher, D. L. | Resuscitation | 2020 |
noradrenalin |
| Is ketamine safe for the pre-hospital sedation of patients with excited delirium secondary to sympathomimetic toxicity? | Adams, Y. | Australasian Journal of Paramedicine | 2019 |
adrenergic receptor stimulating agent |
| Prospective, multi-centric benchmark study assessing delirium: prevalence, incidence and its correlates in hospitalized elderly Lebanese patients | Zrour, C. Haddad, R. Zoghbi, M. Kharsa, Z. Hijazi, M. Naja, W. | Aging Clin Exp Res | 2020 |
Correlated factors |
| Knowledge and attitudes of adolescents with psychiatric disorders and their caregivers towards electroconvulsive therapy in China | Zong, Q. Q. Qi, H. Wang, Y. Y. Zhang, C. Balbuena, L. Ungvari, G. S. An, F. R. Xiang, Y. T. | Asian Journal of Psychiatry | 2020 |
adolescent |
| Does postoperative delirium following elective noncardiac surgery predict long-term mortality? | Ziman, N. Sands, L. P. Tang, C. Zhu, J. Leung, J. M. | Age Ageing | 2020 |
long-term mortality |
| Anxiety administrated by dexmedetomidine to prevent new-onset of postoperative atrial fibrillation in patients undergoing off-pump coronary artery bypass graft | Zi, J. Fan, Y. Dong, C. Zhao, Y. Li, D. Tan, Q. | International Heart Journal | 2020 |
1800014314 |
| Assessment of Melatonergics in Prevention of Delirium: A Systematic Review and Meta-Analysis | Zhu, Y. Jiang, Z. Huang, H. Li, W. Ren, C. Yao, R. Wang, Y. Yao, Y. Li, W. Du, B. Xi, X. | Front Neurol | 2020 |
critical care medicine |
| Geriatric Nutritional Risk Index can predict postoperative delirium and hospital length of stay in elderly patients undergoing non-cardiac surgery | Zhao, Y. Xia, X. Xie, D. Liao, Y. Wang, Y. Chen, L. Ge, N. Yue, J. | Geriatr Gerontol Int | 2020 |
Geriatric Nutritional Risk Index |
| The geriatric nutrition risk index versus the mini-nutritional assessment short form in predicting postoperative delirium and hospital length of stay among older non-cardiac surgical patients: a prospective cohort study | Zhao, Y. Ge, N. Xie, D. Gao, L. Wang, Y. Liao, Y. Yue, J. | BMC Geriatr | 2020 |
Geriatric nutritional risk index |
| Perioperative Multicomponent Interdisciplinary Program Reduces Delirium Incidence in Elderly Patients With Hip Fracture | Zhao, X. Yuan, W. | J Am Psychiatr Nurses Assoc | 2020 |
delirium |
| Emergence delirium is associated with increased postoperative delirium in elderly: a prospective observational study | Zhang, Y. He, S. T. Nie, B. Li, X. Y. Wang, D. X. | J Anesth | 2020 |
Elderly |
| S100β as a potential biomarker of incident delirium: a systematic review and meta-analysis | Zhang, X. Lyu, Y. Wang, D. | Minerva Anestesiol | 2020 | |
| Effects of Dexmedetomidine on Postoperative Delirium and Expression of IL-1β, IL-6, and TNF-α in Elderly Patients After Hip Fracture Operation | Zhang, W. Wang, T. Wang, G. Yang, M. Zhou, Y. Yuan, Y. | Front Pharmacol | 2020 |
dexmedetomidine |
| Nomogram Model for Predicting Risk of Postoperative Delirium After Deep Brain Stimulation Surgery in Patients Older Than 50 Years with Parkinson Disease | Zhan, L. Wang, X. Q. Zhang, L. X. | World Neurosurg | 2020 |
Advanced age |
| Combining Ultrafast Anaesthesia and Minimal Invasive Implantation in HeartMate 3: A Pilot Study | Zayat, R. Ahmad, U. Twarie, L. Moza, A. Schaelte, G. Allham, O. Haneya, A. Khattab, M. Schnoering, H. Autschbach, R. | The Journal of heart and lung transplantation | 2020 |
adult |
| Exosome α-Synuclein Release in Plasma May be Associated With Postoperative Delirium in Hip Fracture Patients | Yuan, Y. Li, Z. Yang, N. Han, Y. Ji, X. Han, D. Wang, X. Li, Y. Liu, T. Yuan, F. He, J. Liu, Y. Ni, C. Zou, P. Wang, G. Guo, X. Zhou, Y. | Front Aging Neurosci | 2020 |
exosome |
| A multicentre, pragmatic, cluster randomised, controlled feasibility trial of the POD system of care | Young, J. Green, J. Farrin, A. Collinson, M. Hartley, S. Smith, J. Teale, E. Siddiqi, N. Inouye, S. K. | Age Ageing | 2020 |
delirium |
| Association of Reversal of Anticoagulation Preoperatively on 30-Day Mortality and Outcomes for Hip Fracture Surgery | Yoo, M. S. Zhu, S. Jiang, S. F. Hammer, H. L. McBride, W. J. McCarthy, C. M. Green, C. E. Ananias, M. P. | American Journal of Medicine | 2020 |
adult |
| Perioperative Complications and Prognosis of Curative Surgical Resection for Spinal Metastases in Elderly Patients | Yonezawa, N. Murakami, H. Demura, S. Kato, S. Yoshioka, K. Shinmura, K. Yokogawa, N. Shimizu, T. Oku, N. Kitagawa, R. Handa, M. Annen, R. Kurokawa, Y. Tsuchiya, H. | World Neurosurgery | 2020 |
titanium cage |
| Risk factors for delirium in intensive care unit and its duration | Yanyan, L. Dajiang, Y. Xiaoya, L. Shao, W. | Zhonghua Wei Zhong Bing Ji Jiu Yi Xue | 2020 |
sedative agent |
| Melatonergic agents in the prevention of delirium: A network meta-analysis of randomized controlled trials | Yang, C. P. Tseng, P. T. Pei-Chen Chang, J. Su, H. Satyanarayanan, S. K. Su, K. P. | Sleep Med Rev | 2020 |
Delirium |
| Oxycodone preemptive analgesia after endoscopic plasma total adenotonsillectomy in children a randomized controlled trial | Wu, J. Gui, Q. Wang, J. Ye, J. Xia, Z. Wang, S. Liu, F. Kong, F. Zhong, L. | Medicine (United States) | 2020 |
ChiCTR-INR-16009116 |
| Delirium screening practice in specialist palliative care units: a survey | Woodhouse, R. Siddiqi, N. Boland, J. W. Featherstone, I. Johnson, M. J. | BMJ Support Palliat Care | 2020 |
delirium |
| Movements and trends in intensive care pain treatment and sedation: What matters to the patient? | Wøien, H. | J Clin Nurs | 2020 |
Adult |
| Quetiapine therapy in critically injured trauma patients is associated with an increased risk of pulmonary complications | Wessels, L. E. Wallace, J. D. Calvo, R. Y. Levko, T. Bowie, J. M. Butler, W. J. Bansal, V. Sise, C. B. Martin, M. J. Sise, M. J. | Am J Surg | 2020 |
Antipsychotic Agents/ adverse effects |
| Combined non-intubated anaesthesia and paravertebral nerve block in comparison with intubated anaesthesia in children undergoing video-assisted thoracic surgery | Wei, W. Fan, Y. Liu, W. Zhao, T. Tian, H. Xu, Y. Tan, Y. Song, X. Ma, D. | Acta Anaesthesiol Scand | 2020 | |
| The occurrence and timing of delirium in acute care hospitalizations in the last year of life: A population-based retrospective cohort study | Webber, C. Watt, C. L. Bush, S. H. Lawlor, P. G. Talarico, R. Tanuseputro, P. | Palliat Med | 2020 |
Delirium |
| Frailty screening in hospitalised older adults: How does the brief Dutch National Safety Management Program perform compared to a more extensive approach? | Warnier, R. M. J. van Rossum, E. van Kuijk, S. M. J. Magdelijns, F. Schols, Jmga Kempen, Gijm | J Clin Nurs | 2020 |
Aged |
| Predicting postoperative delirium after microvascular decompression surgery with machine learning | Wang, Y. Lei, L. Ji, M. Tong, J. Zhou, C. M. Yang, J. J. | J Clin Anesth | 2020 |
Machine learning |
| Propensity score-adjusted three-component mixture model for drug-drug interaction data mining in FDA Adverse Event Reporting System | Wang, X. Li, L. Wang, L. Feng, W. Zhang, P. | Statistics in Medicine | 2020 |
amfebutamone |
| Comparison between Dexmedetomidine and Midazolam for Sedation in Patients with Intubation after Oral and Maxillofacial Surgery | Wang, L. Zhang, T. Huang, L. Peng, W. | Biomed Res Int | 2020 | |
| Comparison of Intranasal Dexmedetomidine and Oral Midazolam for Premedication in Pediatric Dental Patients under General Anesthesia: A Randomised Clinical Trial | Wang, L. Huang, L. Zhang, T. Peng, W. | Biomed Res Int | 2020 | |
| Accelerated magnetic seizure therapy (aMST) for treatment of major depressive disorder: A pilot study | Wang, J. Vila-Rodriguez, F. Ge, R. Gao, S. Gregory, E. Jiang, W. Yang, C. Wang, G. | J Affect Disord | 2020 |
Cognition |
| Development and validation of the delirium risk assessment score (DRAS) | Vreeswijk, R. Kalisvaart, I. Maier, A. B. Kalisvaart, K. J. | Eur Geriatr Med | 2020 |
Delirium |
| Development and validation of the delirium risk assessment score (DRAS) | Vreeswijk, R. Kalisvaart, I. Maier, A. B. Kalisvaart, K. J. | Eur Geriatr Med | 2020 |
Delirium |
| Hospital readmission following transjugular intrahepatic portosystemic shunt: A 14-year single-center experience | Vozzo, C. F. Singh, T. Bullen, J. Sarvepalli, S. McCullough, A. Kapoor, B. | Gastroenterology Report | 2020 |
politef implant |
| Anticholinergic drug exposure at intensive care unit admission affects the occurrence of delirium. A prospective cohort study | Vondeling, A. M. Knol, W. Egberts, T. C. G. Slooter, A. J. C. | Eur J Intern Med | 2020 |
Anticholinergics |
| Delirium Screening in Neurocritical Care and Stroke Unit Patients: A Pilot Study on the Influence of Neurological Deficits on CAM-ICU and ICDSC Outcome | von Hofen-Hohloch, J. Awissus, C. Fischer, M. M. Michalski, D. Rumpf, J. J. Classen, J. | Neurocrit Care | 2020 |
Cam-icu |
| Intensive Care Unit Delirium in Surgical Patients Is Associated with Upregulation in Tryptophan Metabolism | Voils, S. A. Shoulders, B. R. Singh, S. Solberg, L. M. Garrett, T. J. Frye, R. F. | Pharmacotherapy | 2020 |
critical care |
| Vitamin D and Postoperative Delirium After Coronary Artery Bypass Grafting: A Prospective Cohort Study | Velayati, A. Vahdat Shariatpanahi, M. Dehghan, S. Zayeri, F. Vahdat Shariatpanahi, Z. | Journal of Cardiothoracic and Vascular Anesthesia | 2020 |
adult |
| New Delirium Severity Indicators: Generation and Internal Validation in the Better Assessment of Illness (BASIL) Study | Vasunilashorn, S. M. Schulman-Green, D. Tommet, D. Fong, T. G. Hshieh, T. T. Marcantonio, E. R. Metzger, E. D. Schmitt, E. M. Tabloski, P. A. Travison, T. G. Gou, Y. Helfand, B. Inouye, S. K. Jones, R. N. | Dement Geriatr Cogn Disord | 2020 |
Delirium |
| A New Severity Scoring Scale for the 3-Minute Confusion Assessment Method (3D-CAM) | Vasunilashorn, S. M. Devinney, M. J. Acker, L. Jung, Y. Ngo, L. Cooter, M. Huang, R. Marcantonio, E. R. Berger, M. | J Am Geriatr Soc | 2020 | |
| Use of a digital delirium pathway and quality improvement to improve delirium detection in the emergency department and outcomes in an acute hospital | Vardy, E. Collins, N. Grover, U. Thompson, R. Bagnall, A. Clarke, G. Heywood, S. Thompson, B. Wintle, L. Nutt, L. Hulme, S. | Age Ageing | 2020 |
acute |
| Registration of attentional function as a predictor of incident delirium (the RAPID study) | van Zuylen, M. L. Hermanides, J. Ten Hoope, W. Preckel, B. van de Beek, D. van Gool, W. A. Schoenmaker, N. | Alzheimers Dement (N Y) | 2020 |
attentional function |
| Predisposition for delirium and EEG characteristics | van Montfort, S. J. T. van Dellen, E. Wattel, L. L. Kant, I. M. J. Numan, T. Stam, C. J. Slooter, A. J. C. | Clin Neurophysiol | 2020 |
Delirium |
| Geriatric assessment in the prediction of delirium and long-term survival after transcatheter aortic valve implantation | van der Wulp, K. van Wely, M. H. Schoon, Y. Vart, P. Olde Rikkert, M. G. M. Morshuis, W. J. van Royen, N. Verkroost, M. W. A. Gehlmann, H. R. Van Garsse, L. A. F. M. Kievit, P. C. | Journal of Thoracic and Cardiovascular Surgery | 2020 |
aged |
| Complications with focus on delirium during hospital stay related to femoral nerve block compared to conventional pain management among patients with hip fracture – A randomised controlled trial | Unneby, A. Svensson, P. O. Gustafson, P. Y. Lindgren, A. P. B. M. Bergström, U. Olofsson, P. B. | Injury | 2020 |
aged |
| Preoperative Vitamin D Level is Associated with Postoperative Delirium After Cardiac Surgery in Patients Over 65 Years of Age | Tumer, N. B. Tekeli Kunt, A. Gunaydin, S. Ozisik, K. | Heart Surg Forum | 2020 | |
| Epileptic seizure discharges in patients after open chamber cardiac surgery—a prospective prevalence pilot study using continuous electroencephalography | Tschernatsch, M. Juenemann, M. Alhaidar, F. El Shazly, J. Butz, M. Meyer, M. Gerriets, T. Schönburg, M. Schramm, P. | Intensive Care Medicine | 2020 |
adult |
| Pharmacogenomic response of low dose haloperidol in critically ill adults with delirium | Trogrlić, Z. van der Jagt, M. Osse, R. J. Devlin, J. W. Nieboer, D. Koch, B. C. P. van Schaik, R. H. N. Hunfeld, N. G. M. | J Crit Care | 2020 |
Delirium |
| The Impact of Music and Noise-Cancellation on Sedation Requirements During Total Knee Replacement: A Randomized Controlled Trial | Tran, B. W. Nowrouz, M. Y. Dhillon, S. K. Xie, K. K. Breslin, K. M. Golladay, G. J. | Geriatr Orthop Surg Rehabil | 2020 |
acute pain medicine |
| The Prevalence and Impact of Undiagnosed Mild Cognitive Impairment in Elderly Patients Undergoing Thoracic Surgery: A Prospective Cohort Study | Tong, C. Huang, C. Wu, J. Xu, M. Cao, H. | J Cardiothorac Vasc Anesth | 2020 |
Mild cognitive impairment |
| Development of a Palliative Care Toolkit for the COVID-19 Pandemic | Thomas, J. D. Leiter, R. E. Abrahm, J. L. Shameklis, J. C. Kiser, S. B. Gelfand, S. L. Sciacca, K. R. Reville, B. Siegert, C. A. Zhang, H. Lai, L. Sato, R. Smith, L. N. Kamdar, M. M. Greco, L. Lee, K. A. Tulsky, J. A. Lawton, A. J. | Journal of pain and symptom management | 2020 |
adult |
| Interventions to Improve Clinical Outcomes in Older Adults Admitted to a Surgical Service: A Systematic Review and Meta-analysis | Thillainadesan, J. Yumol, M. F. Hilmer, S. Aitken, S. J. Naganathan, V. | J Am Med Dir Assoc | 2020 |
Aging |
| Timeliness of care and adverse event profile in children undergoing general anesthesia or sedation for MRI: An observational prospective cohort study | Thampi, S. Jose, R. Kothandan, P. Jiwanmall, M. Rai, E. | Saudi Journal of Anaesthesia | 2020 |
laryngeal mask |
| Atypical presentation of COVID-19 in a frail older person | Tay, H. S. Harwood, R. | Age Ageing | 2020 |
Covid-19 |
| ADAPT-2: A Randomized Clinical Trial to Reduce Intraoperative EEG Suppression in Older Surgical Patients Undergoing Major Noncardiac Surgery | Tang, C. J. Jin, Z. Sands, L. P. Pleasants, D. Tabatabai, S. Hong, Y. Leung, J. M. | Anesth Analg | 2020 | |
| Dexmedetomidine with sufentanil in intravenous patient-controlled analgesia for relief from postoperative pain, inflammation and delirium after esophageal cancer surgery | Tang, C. Hu, Y. Zhang, Z. Wei, Z. Wang, H. Geng, Q. Shi, S. Wang, S. Wang, J. Chai, X. | Biosci Rep | 2020 |
Dexmedetomidine |
| Cohort study into the neural correlates of postoperative delirium: the role of connectivity and slow-wave activity | Tanabe, S. Mohanty, R. Lindroth, H. Casey, C. Ballweg, T. Farahbakhsh, Z. Krause, B. Prabhakaran, V. Banks, M. I. Sanders, R. D. | Br J Anaesth | 2020 |
cognitive dysfunction |
| Preoperative circadian physical activity rhythm and postoperative delirium in cardiovascular surgery patients | Tan, C. Saito, N. Miyawaki, I. Shiotani, H. | Chronobiol Int | 2020 |
Postoperative delirium |
| Real-world evidence of the safety and efficacy profile of suvorexant in elderly patients with insomnia: a sub-analysis of the post-marketing drug-use results survey in Japan | Takeuchi, Y. Sano, H. Asai, Y. Miyazaki, M. Iwakura, M. Maeda, Y. | Current Medical Research and Opinion | 2020 |
hypnotic agent |
| Electroencephalography-Guided Anesthetic Delivery for Preventing Postoperative Delirium in Adults: An Updated Meta-analysis | Sun, Y. Ye, F. Wang, J. Ai, P. Wei, C. Wu, A. Xie, W. | Anesth Analg | 2020 | |
| Risk and Consequences of Postoperative Delirium in Cardiac Surgery | Sugimura, Y. Sipahi, N. F. Mehdiani, A. Petrov, G. Awe, M. Minol, J. P. Boeken, U. Korbmacher, B. Lichtenberg, A. Dalyanoglu, H. | Thorac Cardiovasc Surg | 2020 | |
| Risk of Hospitalized Falls and Hip Fractures in 22,103 Older Adults Receiving Mental Health Care vs 161,603 Controls: A Large Cohort Study | Stubbs, B. Perara, G. Koyanagi, A. Veronese, N. Vancampfort, D. Firth, J. Sheehan, K. De Hert, M. Stewart, R. Mueller, C. | J Am Med Dir Assoc | 2020 |
Hip fracture |
| Pharmacist-driven discontinuation of antipsychotics for ICU delirium: A quasi-experimental study | Stuart, M. M. Smith, Z. R. Payter, K. A. Martz, C. R. To, L. Swiderek, J. L. Coba, V. E. Peters, M. A. | JACCP Journal of the American College of Clinical Pharmacy | 2020 |
adult |
| Interventions to prevent in-hospital falls in older people with cognitive impairment for further research: a mixed studies review | Stockwell-Smith, G. Adeleye, A. Chaboyer, W. Cooke, M. Phelan, M. Todd, J. A. Grealish, L. | J Clin Nurs | 2020 |
In-hospital fall |
| Early Identification of Delirium in Intensive Care Unit Patients: Improving the Quality of Care | Spiegelberg, J. Song, H. Pun, B. Webb, P. Boehm, L. M. | Crit Care Nurse | 2020 | |
| Efficacy and Safety of Dexmedetomidine for Prolonged Sedation in the PICU: A Prospective Multicenter Study (PROSDEX) | Sperotto, F. Mondardini, M. C. Dell'Oste, C. Vitale, F. Ferrario, S. Lapi, M. Ferrero, F. Dusio, M. P. Rossetti, E. Daverio, M. Amigoni, A. | Pediatr Crit Care Med | 2020 | |
| Restricted versus liberal intraoperative benzodiazepine use in cardiac anaesthesia for reducing delirium (B-Free Pilot): a pilot, multicentre, randomised, cluster crossover trial | Spence, J. Belley-Côté, E. Jacobsohn, E. Lee, S. F. Whitlock, R. Bangdiwala, S. Syed, S. Sarkaria, A. MacIsaac, S. Lengyel, A. Long, S. Um, K. McIntyre, W. F. Kavosh, M. Fast, I. Arora, R. Lamy, A. Connolly, S. Devereaux, P. J. | Br J Anaesth | 2020 |
awareness |
| Thoracic continuous spinal anesthesia for high-risk comorbid older patients undergoing major abdominal surgery: one-year experience of an Italian geriatric hospital | Spannella, F. Giulietti, F. Damiani, E. Faloia, L. Stronati, M. Venezia, A. Vincenzi, P. Castellani, D. Boccoli, G. Dellabella, M. Giampieri, M. Sarzani, R. Starnari, R. | Minerva Anestesiol | 2020 | |
| Identification of distinct clinical phenotypes in mechanically ventilated patients with acute brain dysfunction using cluster analysis | Souza-Dantas, V. C. Dal-Pizzol, F. Tomasi, C. D. Spector, N. Soares, M. Bozza, F. A. Póvoa, P. Salluh, J. I. F. | Medicine (Baltimore) | 2020 |
Apache |
| Validation of a multidisciplinary care protocol for critically ill patients with delirium | Souza, T. L. Azzolin, K. O. Souza, E. N. | Revista gaucha de enfermagem | 2020 |
adult |
| Hospital Costs and Reimbursement Model for a Geriatric Emergency Department | Southerland, L. T. Savage, E. L. Muska Duff, K. Caterino, J. M. Bergados, T. R. Hunold, K. M. Finnegan, G. I. Archual, G. | Acad Emerg Med | 2020 | |
| Natural light exposure and delirium in ICU: does the dark side cloud everything? | Sonneville, R. Smonig, R. Dupuis, C. Bouadma, L. de Montmollin, E. Timsit, J. F. | Annals of Intensive Care | 2020 |
sedative agent |