What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Risk Stratification of QTc Prolongation in Critically Ill Patients Receiving Antipsychotics for the Management of Delirium Symptoms
- Authors
- Sadlonova, M. Beach, S. R. Funk, M. C. Rosen, J. H. Ramirez Gamero, A. F. Karlson, R. A. Huffman, J. C. Celano, C. M.
- Year
- 2025
- Journal
- J Intensive Care Med
- Abstract
Background Patients experiencing significant agitation or perceptual disturbances related to delirium in an intensive care setting may benefit from short-term treatment with an antipsychotic medication. Some antipsychotic medications may prolong the QTc interval, which increases the risk of potentially fatal ventricular arrhythmias. In this targeted review, we describe the evidence regarding the relationships between antipsychotic medications and QTc prolongation and practical methods for monitoring the QTc interval and mitigating arrhythmia risk. Methods Searches of PubMed and Cochrane Library were performed to identify studies, published before February 2023, investigating the relationships between antipsychotic medications and QTc prolongation or arrhythmias. Results Most antipsychotic medications commonly used for the management of delirium symptoms (eg, intravenous haloperidol, olanzapine, quetiapine) cause a moderate degree of QTc prolongation. Among other antipsychotics, those most likely to cause QTc prolongation are iloperidone and ziprasidone, while aripiprazole and lurasidone appear to have minimal risk for QTc prolongation. Genetic vulnerabilities, female sex, older age, pre-existing cardiovascular disease, electrolyte abnormalities, and non-psychiatric medications also increase the risk of QTc prolongation. For individuals at risk of QTc prolongation, it is essential to measure the QTc interval accurately and consistently and consider medication adjustments if needed. Conclusions Antipsychotic medications are one of many risk factors for QTc prolongation. When managing agitation related to delirium, it is imperative to assess an individual patient’s risk for QTc prolongation and to choose a medication and monitoring strategy commensurate to the risks. In intensive care settings, we recommend regular ECG monitoring, using a linear regression formula to correct for heart rate. If substantial QTc prolongation (eg, QTc > 500 msec) is present, a change in pharmacologic treatment can be considered, though a particular medication may still be warranted if the risks of discontinuation (eg, extreme agitation, removal of invasive monitoring devices) outweigh the risks of arrhythmias. Aims This review aims to summarize the current literature on relationships between antipsychotic medications and QTc prolongation and to make practical clinical recommendations towards the approach of antipsychotic medication use for the management of delirium-related agitation and perceptual disturbances in intensive care settings.
- PMID
PMID: 38130132
- Keywords
Humans *Antipsychotic Agents/adverse effects/therapeutic use *Delirium/drug therapy *Long QT Syndrome/chemically induced Critical Illness Risk Assessment Risk Factors Female Intensive Care Units Male Electrocardiography QTc prolongation agitation antipsychotics drug safety neuroleptics
- Page(s)
- Volume
- Issue
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| A Multi-Phase Quality Improvement Initiative for the Treatment of Active Delirium in Older Persons | Friedman, J. I. Li, L. Kirpalani, S. Zhong, X. Freeman, R. Cheng, Y. T. Alfonso, F. L. McAlpine, G. Vakil, A. Macon, B. Francaviglia, P. Cassara, M. LoPachin, V. Reina, K. Davis, K. Reich, D. Craven, C. K. Mazumdar, M. Siu, A. L. | J Am Geriatr Soc | 2020 |
Confusion Assessment Method |
| Delirium diagnostic tool-provisional (DDT-Pro) scores in delirium, subsyndromal delirium and no delirium | Franco, J. G. Trzepacz, P. T. Sepúlveda, E. Ocampo, M. V. Velásquez-Tirado, J. D. Zaraza, D. R. Restrepo, C. Giraldo, A. M. Serna, P. A. Zuluaga, A. López, C. | Gen Hosp Psychiatry | 2020 |
Cluster analysis |
| A multimodal sevoflurane-based sedation regimen in combination with targeted temperature management in post-cardiac arrest patients reduces the incidence of delirium: An observational propensity score-matched study | Foudraine, N. A. Algargoush, A. van Osch, F. H. Bos, A. T. | Resuscitation | 2020 |
Cardiac arrest |
| Association of Plasma Neurofilament Light with Postoperative Delirium | Fong, T. G. Vasunilashorn, S. M. Ngo, L. Libermann, T. A. Dillon, S. T. Schmitt, E. M. Pascual-Leone, A. Arnold, S. E. Jones, R. N. Marcantonio, E. R. Inouye, S. K. | Ann Neurol | 2020 |
Aged |
| Course and Recognition of Poststroke Delirium: A Prospective Noninferiority Trial of Delirium Screening Tools | Fleischmann, R. Warwas, S. Andrasch, T. Kunz, R. Witt, C. Mengel, A. von Sarnowski, B. | Stroke | 2020 |
delirium |
| The collateral history: an overlooked core clinical skill | Fitzpatrick, D. Doyle, K. Finn, G. Gallagher, P. | Eur Geriatr Med | 2020 |
Clinical training |
| Management of delirium superimposed on dementia in a dementia service | FitzGerald, J. Yan, M. Bandecar, A. Ratnasabapathy, V. Rubinsztein, J. Hatfield, C. Ruhi, S. | Progress in Neurology and Psychiatry | 2020 |
adult |
| Partnering With Family Members to Detect Delirium in Critically Ill Patients | Fiest, K. M. Krewulak, K. D. Ely, E. W. Davidson, J. E. Ismail, Z. Sept, B. G. Stelfox, H. T. | Crit Care Med | 2020 |
adult |
| The correlation of intraoperative hypotension and postoperative cognitive impairment: a meta-analysis of randomized controlled trials | Feng, X. Hu, J. Hua, F. Zhang, J. Zhang, L. Xu, G. | BMC Anesthesiol | 2020 |
Intraoperative hypotension |
| The effect of joints range of motion exercises on delirium prevention in patients admitted to intensive care units | Farzammanesh, A. Jahani, S. Rashidi, M. Maraghi, E. Ravanbakhsh, M. | International Journal of Pharmaceutical and Phytopharmacological Research | 2020 |
IRCT20180114038362N1 |
| Sleep and Delirium in Older Adults | Farasat, S. Dorsch, J. J. Pearce, A. K. Moore, A. A. Martin, J. L. Malhotra, A. Kamdar, B. B. | Curr Sleep Med Rep | 2020 |
Acetylcholine |
| Association between use of angiotensin-converting enzyme inhibitors or angiotensin receptor blockers and postoperative delirium | Farag, E. Farag, E. Liang, C. Liang, C. Mascha, E. J. Mascha, E. J. Argalious, M. Y. Ezell, J. Maheshwari, K. Esa, W. A. S. Troianos, C. A. Sessler, D. I. | Anesthesiology | 2020 |
adult |
| Delirium in cardiology: An old problem, a new emergency | Falsini, G. Romanelli, S. Insana, L. Frongillo, D. Grotti, S. Angioli, P. Ducci, K. Liistro, F. Calchetti, B. Rossi, R. Bolognese, L. | Giornale Italiano di Cardiologia | 2020 |
attitude to illness |
| Surveying work-as-done in post-operative delirium risk factors collection and diagnosis monitoring | Falegnami, A. Patriarca, R. Costantino, F. Di Gravio, G. Bilotta, F. | Appl Ergon | 2020 |
RiskSOAP |
| Psychiatric disorders, delirium and mortality in patients referred for consultation in a burn center: A four-year retrospective study | Erdoğan, E. Delibaş, D. H. | Medical Journal of Bakirkoy | 2020 |
antidepressant agent |
| Delirium in Older People with COVID-19: Clinical Scenario and Literature Review | Emmerton, D. Abdelhafiz, A. | SN Compr Clin Med | 2020 |
Covid-19 |
| "It should not be that difficult to manage a condition that is so frequent": A qualitative study on hospital nurses' experience of delirium guidelines | Emme, C. | J Clin Nurs | 2020 |
Adult |
| Where should patients with or at risk of delirium be treated in an acute care system? Comparing the rates of delirium in patients receiving usual care versus alternative care: a systematic review and meta-analysis | Ekeozor, C. U. Jeyaruban, D. Lasserson, D. | Int J Clin Pract | 2020 |
Acute care |
| Effect of General Versus Spinal Anesthesia on Postoperative Delirium and Early Cognitive Dysfunction in Elderly Patients | Ehsani, R. Djalali Motlagh, S. Zaman, B. Sehat Kashani, S. Ghodraty, M. R. | Anesth Pain Med | 2020 |
Delirium |
| Anticholinergic Drug Burden and Delirium: A Systematic Review | Egberts, A. Moreno-Gonzalez, R. Alan, H. Ziere, G. Mattace-Raso, F. U. S. | Journal of the American Medical Directors Association | 2020 |
adult |
| Antipsychotics and Lorazepam During Delirium: Are We Harming Older Patients? A Real-Life Data Study | Egberts, A. Alan, H. Ziere, G. Mattace-Raso, F. U. S. | Drugs and Aging | 2020 |
acutely ill patient |
| Delirium in Internal Medicine Departments in a Tertiary Hospital in Israel: Occurrence, Detection Rates, Risk Factors, and Outcomes | Efraim, N. T. Zikrin, E. Shacham, D. Katz, D. Makulin, E. Barski, L. Zeller, L. Bartal, C. Freud, T. Lebedinski, S. Press, Y. | Front Med (Lausanne) | 2020 |
delirium |
| Development and validation of an aetiology in delirium diagnostic support tool | Eeles, E. Huang, L. Dakin, L. Ling, C. Dunn, E. Fraser, J. Dissanayaka, N. N. | Age Ageing | 2020 |
aetiology |
| Association of Geriatric Events With Perioperative Outcomes After Elective Inpatient Surgery | Dworsky, J. Q. Shellito, A. D. Childers, C. P. Copeland, T. P. Maggard-Gibbons, M. Tan, H. J. Saliba, D. Russell, M. M. | J Surg Res | 2020 |
Elderly |
| Is there an association between subjective sleep quality and daily delirium occurrence in critically ill adults? A post hoc analysis of a randomised controlled trial | Duprey, M. S. Devlin, J. W. Skrobik, Y. | BMJ Open Respir Res | 2020 |
clinical epidemiology |
| Approaches to Optimize Medication Data Analysis in Clinical Cohort Studies | Duprey, M. S. Devlin, J. W. Briesacher, B. A. Travison, T. G. Griffith, J. L. Inouye, S. K. | J Am Geriatr Soc | 2020 |
delirium |
| Delirium definition influences prediction of functional survival in patients one-year postcardiac surgery | Dubiel, C. Hiebert, B. M. Stammers, A. N. Sanjanwala, R. M. Tangri, N. Singal, R. K. Manji, R. A. Rudolph, J. L. Arora, R. C. | J Thorac Cardiovasc Surg | 2020 |
cardiac surgery |
| Prevalence and outcome of delirium among acute general medical inpatients in Cape Town, South Africa | Du Plooy, N. Day, C. Manning, K. Abdullah, F. James, K. Grace, L. Vorajee, N. April, C. Peter, J. Peter, J. Raubenheimer, P. J. | South African Medical Journal | 2020 |
indwelling urinary catheter |
| Delirium Post-Stroke-Influence on Post-Stroke Dementia (Research Study-Part of the PROPOLIS Study) | Droś, J. Kowalska, K. Pasińska, P. Szyper-Maciejowska, A. Gorzkowska, A. Klimkowicz-Mrowiec, A. | J Clin Med | 2020 |
cognitive impairment |
| Providing Evidence-Based Care, Day and Night: A Quality Improvement Initiative to Improve Intensive Care Unit Patient Sleep Quality | Douglas, S. L. Hobbs, H. A. Sibley, S. R. Digby, G. C. | J Intensive Care Med | 2020 |
critical care |
| An Implementation-Effectiveness Study of a Perioperative Delirium Prevention Initiative for Older Adults | Donovan, A. L. Braehler, M. R. Robinowitz, D. L. Lazar, A. A. Finlayson, E. Rogers, S. Douglas, V. C. Whitlock, E. L. | Anesth Analg | 2020 |
Aged |
| Effectiveness of a multidisciplinary comprehensive intervention model based on the Hospital Elderly Life Program to prevent delirium in patients with severe acute pancreatitis | Dong, Z. Song, J. Ge, M. Lin, C. Zhang, J. Chen, J. Wu, Y. | Ann Palliat Med | 2020 |
Pancreatitis |
| Does Preoperative Comprehensive Geriatric Assessment and Frailty Predict Postoperative Complications? | Dogrul, R. T. Dogrul, A. B. Konan, A. Caglar, O. Sumer, F. Caliskan, H. Kizilarslanoglu, M. C. Kilic, M. K. Balci, C. Arik, G. Aycicek, G. S. Ozsurekci, C. Halil, M. Cankurtaran, M. Yavuz, B. B. | World journal of surgery | 2020 |
aged |
| Preoperative Acute Pain Is Associated with Postoperative Delirium | Ding, X. Gao, X. Chen, Q. Jiang, X. Li, Y. Xu, J. Qin, G. Lu, S. Huang, D. | Pain Med | 2020 |
C-Reactive Protein |
| Effects of electroencephalography and regional cerebral oxygen saturation monitoring on perioperative neurocognitive disorders: a systematic review and meta-analysis | Ding, L. Chen, D. X. Li, Q. | BMC Anesthesiol | 2020 |
Electroencephalography |
| The Addition of Intravenous Propofol and Ketorolac to a Sevoflurane Anesthetic Lessens Emergence Agitation in Children Having Bilateral Myringotomy with Tympanostomy Tube Insertion: A Prospective Observational Study | d'Eon, B. Hackmann, T. Wright, A. S. | Children (Basel) | 2020 |
emergence agitation |
| Preoperative Nutritional Status and Risk for Subsyndromal Delirium in Older Adults Following Joint Replacement Surgery | Denny, D. L. Trotter, T. Lindseth, G. | Orthopedic nursing | 2020 |
aged |
| Non-pharmacological interventions to reduce the incidence and duration of delirium in critically ill patients: A systematic review and network meta-analysis | Deng, L. X. Cao, L. Zhang, L. N. Peng, X. B. Zhang, L. | J Crit Care | 2020 |
Delirium prevention |
| Multidimensional nursing interventions effect on delirium and hospital admission duration | Dehghani, S. Asadizaker, M. Adineh, M. Maraghi, E. Akbarian, S. Ramezani, B. | International Journal of Pharmaceutical and Phytopharmacological Research | 2020 |
IRCT20181005041233N1 |
| Effects of pain, sedation and delirium monitoring on clinical and economic outcome: A retrospective study | Deffland, M. Spies, C. Weiss, B. Keller, N. Jenny, M. Kruppa, J. Balzer, F. | PLoS ONE | 2020 |
NCT02265263 |
| The association of post-operative delirium with health-related quality of life and mortality after lung transplantation | DeBolt, C. Gao, Y. Sutter, N. Soong, A. Trinh, B. N. Kukreja, J. Kleinhenz, M. Venado, A. Leard, L. E. Hays, S. Greenland, J. R. Shah, R. J. Douglas, V. Kolaitis, N. A. Diamond, J. M. Smith, P. J. Singer, J. P. | American Journal of Respiratory and Critical Care Medicine | 2020 |
adult |
| Development and validation of a delirium risk prediction preoperative model for cardiac surgery patients (DELIPRECAS): An observational multicentre study | de la Varga-Martínez, O. Gómez-Pesquera, E. Muñoz-Moreno, M. F. Marcos-Vidal, J. M. López-Gómez, A. Rodenas-Gómez, F. Ramasco, F. Álvarez-Refojo, F. Tamayo, E. Gómez-Sánchez, E. | J Clin Anesth | 2020 |
Cardiac surgery |
| The Effect of Multiple Assessments on Delirium Detection: a Pilot Study | de Freitas, S. A. Wong, E. Lee, J. Y. Reppas-Rindlisbacher, C. Gabor, C. Curkovic, A. Patterson, C. J. | Can Geriatr J | 2020 |
3d-cam |
| Delirium Detection Based on the Clinical Experience of Pediatric Intensivists | de Castro, R. E. V. de Magalhães-Barbosa, M. C. Cunha, Ajlad Cheniaux, E. Prata-Barbosa, A. | Pediatr Crit Care Med | 2020 | |
| Kidney Function Modifies the Effect of Intraoperative Opioid Dosage on Postoperative Delirium | Davani, A. B. Snyder, S. H. Oh, E. S. Mears, S. C. Crews, D. C. Wang, N. Y. Sieber, F. E. | J Am Geriatr Soc | 2020 |
analgesics, opioids |
| One-year mortality rate after fragility hip fractures and associated risk in Nan, Thailand | Daraphongsataporn, N. Saloa, S. Sriruanthong, K. Philawuth, N. Waiwattana, K. Chonyuen, P. Pimolbutr, K. Sucharitpongpan, W. | Osteoporosis and Sarcopenia | 2020 |
aged |
| Abnormal Sleep, Circadian Rhythm Disruption, and Delirium in the ICU: Are They Related? | Daou, M. Telias, I. Younes, M. Brochard, L. Wilcox, M. E. | Front Neurol | 2020 |
ICU acquired delirium |
| Delirium prevention and treatment in the emergency department (ED): a systematic review protocol | Dahlstrom, E. B. Han, J. H. Healy, H. Kennedy, M. Arendts, G. Lee, J. Carpenter, C. Lee, S. | BMJ Open | 2020 |
accident & emergency medicine |
| Pathomechanisms of Non-Traumatic Acute Brain Injury in Critically Ill Patients | Dabrowski, W. Siwicka-Gieroba, D. Gasinska-Blotniak, M. Zaid, S. Jezierska, M. Pakulski, C. Williams Roberson, S. Wesley Ely, E. Kotfis, K. | Medicina (Kaunas) | 2020 |
critical illness |
| Low molecular weight heparin in COVID-19 patients prevents delirium and shortens hospitalization | D’Ardes, D. Carrarini, C. Russo, M. Dono, F. Speranza, R. Digiovanni, A. Martinotti, G. Di Iorio, A. Onofrj, M. Cipollone, F. Bonanni, L. | Neurological Sciences | 2020 |
adult |
| Postoperative delirium: why, what, and how to confront it at your institution | Curtis, M. S. Forman, N. A. Donovan, A. L. Whitlock, E. L. | Curr Opin Anaesthesiol | 2020 |
Aged |
| Delirium due to intoxication with quetiapine: A systematic literature review | Crombez, S. van Den Wijngaert, V. Demyttenaere, K. de Fruyt, J. | Tijdschrift voor Psychiatrie | 2020 |
physostigmine |
| Postoperative delirium in patients with head and neck oral cancer in the West of Scotland | Crawford, J. E. Zubair, F. Baniulyte, G. Wales, C. J. Ansell, M. Thomson, E. Hislop, S. MacIver, C. Devine, J. McCaul, J. Young, D. McMahon, J. | Br J Oral Maxillofac Surg | 2020 |
Eras |
| Diagnosis, prevention, and management of delirium in the intensive cardiac care unit | Cortés-Beringola, A. Vicent, L. Martín-Asenjo, R. Puerto, E. Domínguez-Pérez, L. Maruri, R. Moreno, G. Vidán, M. T. Fernando, Arribas Bueno, H. | Am Heart J | 2020 | |
| Serum DBI and biomarkers of neuroinflammation in Alzheimer's disease and delirium | Conti, E. Andreoni, S. Tomaselli, D. Storti, B. Brovelli, F. Acampora, R. Da Re, F. Appollonio, I. Ferrarese, C. Tremolizzo, L. | Neurol Sci | 2020 |
Alzheimer’s disease |
| A complication of coronavirus disease 2019: delirium | Cipriani, G. Danti, S. Nuti, A. Carlesi, C. Lucetti, C. Di Fiorino, M. | Acta Neurol Belg | 2020 |
Betacoronavirus |
| Post-operative delirium and cognitive decline in kidney transplantation | Chu, N. M. Chen, X. Segev, D. L. McAdams-DeMarco, M. | Journal of the American Society of Nephrology | 2020 |
adult |
| Vitamin D and Delirium in Older Adults: A Case-Control Study in Geriatric Acute Care Unit | Chouët, J. Sacco, G. Karras, S. N. Llewellyn, D. J. Sánchez-Rodríguez, D. Annweiler, C. | Front Neurol | 2020 |
cognition |
| Risk factors for postoperative delirium in elderly patients after spinal fusion surgery | Choi, S. Jung, I. Yoo, B. Lee, S. Kim, M. C. | Anesth Pain Med (Seoul) | 2020 |
Aged |
| Multimodal Education Program to Improve Nurses' Knowledge and Confidence on Delirium Recognition in a Surgical-Trauma Intermediate-Care Setting | Choi, M. DeGennaro, R. Blevins, C. | Journal of doctoral nursing practice | 2020 |
adult |
| Development and validation of delirium prediction model for critically ill adults parameterized to ICU admission acuity | Cherak, S. J. Soo, A. Brown, K. N. Ely, E. W. Stelfox, H. T. Fiest, K. M. | PLoS One | 2020 |
Apache |
| Association of Glucose Variability and ICU Delirium of Patients after Liver Transplantation | Cheng, J. L. Dong, M. L. Zhang, Z. W. Liao, X. L. Yang, J. Y. Kang, Y. | Journal of Sichuan University. Medical science edition | 2020 |
adverse event |
| Modified Frailty Index Independently Predicts Postoperative Delirium and Delayed Neurocognitive Recovery After Elective Total Joint Arthroplasty | Chen, Y. Qin, J. | J Arthroplasty | 2020 |
delayed neurocognitive recovery |
| Risk predictive models for delirium in the intensive care unit: a systematic review and meta-analysis | Chen, X. Lao, Y. Zhang, Y. Qiao, L. Zhuang, Y. | Ann Palliat Med | 2020 |
Delirium |
| Diagnostic accuracy of the CAM-ICU and ICDSC in detecting intensive care unit delirium: A bivariate meta-analysis | Chen, T. J. Chung, Y. W. Chang, H. C. R. Chen, P. Y. Wu, C. R. Hsieh, S. H. Chiu, H. Y. | International journal of nursing studies | 2020 |
adult |
| Atypical Sleep and Postoperative Delirium in the Cardiothoracic Surgical Intensive Care Unit: A Pilot Prospective Study | Chen, Q. Peng, Y. Lin, Y. Li, S. Huang, X. Chen, L. W. | Nat Sci Sleep | 2020 |
atypical sleep |
| Delirium risk prediction models for intensive care unit patients: A systematic review | Chen, J. Yu, J. Zhang, A. | Intensive Crit Care Nurs | 2020 |
Delirium |
| The role of statins in the management of delirium: Recent advances | Chen, J. Wang, Y. Hu, X. Li, M. Xiong, K. Zhang, Z. Chen, Q. | CNS Neurol Disord Drug Targets | 2020 |
Delirium |
| Analysis of Risk Factors for Postoperative Delirium After Liver Transplantation | Chen, J. Wang, H. He, Z. Li, T. | Neuropsychiatr Dis Treat | 2020 |
ammonia |
| Analgesia and sedation in patients with ARDS | Chanques, G. Constantin, J. M. Devlin, J. W. Ely, E. W. Fraser, G. L. Gélinas, C. Girard, T. D. Guérin, C. Jabaudon, M. Jaber, S. Mehta, S. Langer, T. Murray, M. J. Pandharipande, P. Patel, B. Payen, J. F. Puntillo, K. Rochwerg, B. Shehabi, Y. Strøm, T | Intensive Care Med | 2020 |
Analgesia/methods/ standards |
| Delirium Prevention, Detection, and Treatment in Emergency Medicine Settings: A Geriatric Emergency Care Applied Research (GEAR) Network Scoping Review and Consensus Statement | Carpenter, C. R. Hammouda, N. Linton, E. A. Doering, M. Ohuabunwa, U. K. Ko, K. J. Hung, W. W. Shah, M. N. Lindquist, L. A. Biese, K. Wei, D. Hoy, L. Nerbonne, L. Hwang, U. Dresden, S. M. | Academic Emergency Medicine | 2020 |
aged |
| Geriatric emergency care applied research network cognitive impairment priorities consensus conference | Carpenter, C. R. Hammouda, N. Linton, E. Doerring, M. Ohuabunwa, U. Ko, K. Hung, W. Dresden, S. M. Shah, M. N. Lindquist, L. Biese, K. Wei, D. Hwang, U. | Academic Emergency Medicine | 2020 |
adult |
| Identifying and Responding to Delirium in Acute Stroke: Clinical Team Members' Understandings | Carin-Levy, G. Nicol, K. van Wijck, F. Mead, G. McVittie, C. | Qualitative health research | 2020 |
adult |
| Antipsychotic use in the prevention and treatment of intensive care unit delirium in pediatric patients | Capino, A. C. Thomas, A. N. Baylor, S. Hughes, K. M. Miller, J. L. Johnson, P. N. | Journal of Pediatric Pharmacology and Therapeutics | 2020 |
haloperidol |
| Screening instruments for cognitive impairment in older patients in the Emergency Department: a systematic review and meta-analysis | Calf, A. H. Pouw, M. A. van Munster, B. C. Burgerhof, J. G. M. de Rooij, S. E. Smidt, N. | Age Ageing | 2020 |
Emergency Department |
| Prevalence, Predictors, and Early Outcomes of Post-operative Delirium in Patients With Type A Aortic Dissection During Intensive Care Unit Stay | Cai, S. Zhang, X. Pan, W. Latour, J. M. Zheng, J. Zhong, J. Gao, J. Lv, M. Luo, Z. Wang, C. Zhang, Y. | Front Med (Lausanne) | 2020 |
delirium |
| Toxin-Induced Acute Delirium | Cai, A. Cai, X. | Neurol Clin | 2020 |
Anticholinergic |
| Cognitive and psychosocial outcomes of mechanically ventilated intensive care patients with and without delirium | Bulic, D. Bennett, M. Georgousopoulou, E. N. Shehabi, Y. Pham, T. Looi, J. C. L. van Haren, F. M. P. | Ann Intensive Care | 2020 |
Cognition |
| The influence of a serious game's narrative on students' attitudes and learning experiences regarding delirium: an interview study | Buijs-Spanjers, K. R. Harmsen, A. Hegge, H. H. Spook, J. E. de Rooij, S. E. Jaarsma, Dadc | BMC Med Educ | 2020 |
Delirium |
| Preoperative prognostic factors associated with postoperative delirium in older people undergoing surgery: protocol for a systematic review and individual patient data meta-analysis | Buchan, T. A. Sadeghirad, B. Schmutz, N. Goettel, N. Foroutan, F. Couban, R. Mbuagbaw, L. Dodsworth, B. T. | Syst Rev | 2020 |
Elderly |
| Impact of Therapeutic Music Listening on Intensive Care Unit Patients: A Pilot Study | Browning, S. G. Watters, R. Thomson-Smith, C. | Nurs Clin North Am | 2020 |
Aged |
| Association between delirium in the intensive care unit and subsequent neuropsychiatric disorders | Brown, K. N. Soo, A. Faris, P. Patten, S. B. Fiest, K. M. Stelfox, H. T. | Crit Care | 2020 |
Aged |
| Association of Positive Delirium Screening with Incident Dementia in Skilled Nursing Facilities | Briesacher, B. A. Koethe, B. Olivieri-Mui, B. Saczynski, J. S. Fick, D. M. Devlin, J. W. Marcantonio, E. R. | J Am Geriatr Soc | 2020 |
delirium |
| Economic Burden of Postoperative Neurocognitive Disorders Among US Medicare Patients | Boone, M. D. Sites, B. von Recklinghausen, F. M. Mueller, A. Taenzer, A. H. Shaefi, S. | JAMA Netw Open | 2020 |
Aged |
| Hospital Elder Life Program in Long-Term Care (HELP-LTC): A Cluster Randomized Controlled Trial | Boockvar, K. S. Judon, K. M. Eimicke, J. P. Teresi, J. A. Inouye, S. K. | J Am Geriatr Soc | 2020 |
delirium |
| Pain Incidence, Treatment, and Associated Symptoms in Hospitalized Persons with Dementia | Boltz, M. Resnick, B. Kuzmik, A. Mogle, J. Jones, J. R. Arendacs, R. BeLue, R. Cacchione, P. Galvin, J. E. | Pain Manag Nurs | 2020 | |
| Disparities in Physical and Psychological Symptoms in Hospitalized African American and White Persons with Dementia | Boltz, M. BeLue, R. Resnick, B. Kuzmik, A. Galik, E. Jones, J. R. Arendacs, R. Sinvani, L. Mogle, J. Galvin, J. E. | J Aging Health | 2020 |
African Americans |
| The prevalence rates and adversities of delirium: Too common and disadvantageous | Boettger, S. Zipser, C. M. Bode, L. Spiller, T. Deuel, J. Osterhoff, G. Ernst, J. Petry, H. Volbracht, J. von Känel, R. | Palliat Support Care | 2020 |
Delirium |
| Assessing delirium with nursing care instruments: Evaluation of the cognitive and associated domains | Bode, L. Fuchs, S. Gehrke, S. Ernst, J. Schubert, M. Nuñez, D. G. von Känel, R. Boettger, S. | Palliat Support Care | 2020 |
Assessment |
| Iranian Nurses Perception and Practices for Delirium Assessment in Intensive Care Units | Biyabanaki, F. Arab, M. Dehghan, M. | Indian J Crit Care Med | 2020 |
Assessment |
| How to fight against overtreatment? Example of neuroleptic prescriptions for acute delirium | Bianchi, C. Blondet, F. Aebischer, O. Méan, M. | Revue Medicale Suisse | 2020 |
neuroleptic agent |
| Clinical Presentation of COVID19 in Dementia Patients | Bianchetti, A. Rozzini, R. Guerini, F. Boffelli, S. Ranieri, P. Minelli, G. Bianchetti, L. Trabucchi, M. | Journal of Nutrition, Health and Aging | 2020 |
aged |
| Validation of two nurse-based screening tools for delirium in elderly patients in general medical wards | Bergjan, M. Zilezinski, M. Schwalbach, T. Franke, C. Erdur, H. Audebert, H. J. Hauß, A. | BMC Nurs | 2020 |
Confusion |
| Prevalence and management of delirium in intensive care units in the Netherlands: An observational multicentre study | Berger, E. Wils, E. J. Vos, P. van Santen, S. Koets, J. Slooter, A. J. C. van der Woude, M. Koopmans, M. Rinket, M. A. Hoiting, O. Hoogendoorn, E. E. Streefkerk, J. O. de Vreede, E. W. Riekerk, B. Simons, K. S. Toscano, E. Schoonderbeek, F. J. Hofstra, L. | Intensive Crit Care Nurs | 2020 |
Critically ill |
| Effect of Exogenous Melatonin Administration in Critically Ill Patients on Delirium and Sleep: A Randomized Controlled Trial | Bellapart, J. Appadurai, V. Lassig-Smith, M. Stuart, J. Zappala, C. Boots, R. | Crit Care Res Pract | 2020 | |
| Delirium, functional decline and quality of life after transcatheter aortic valve implantation: An explorative study | Beishuizen, S. J. Festen, S. Loonstra, Y. E. van der Werf, H. W. de Rooij, S. E. van Munster, B. C. | Geriatr Gerontol Int | 2020 |
activities of daily living |
| Clinical outcomes in patients admitted to hospital with cervical spine fractures or with hip fractures | Baxter, J. Lisk, R. Osmani, A. Yeong, K. Robin, J. Fluck, D. Fry, C. H. Han, T. S. | Intern Emerg Med | 2020 |
Discharge destination |
| Frequency and Implications of Complications in the ICU After Status Epilepticus: No Calm After the Storm | Baumann, S. M. Semmlack, S. De Marchis, G. M. Hunziker, S. Rüegg, S. Marsch, S. Sutter, R. | Critical care medicine | 2020 |
adult |
| Neurological Complications and Noninvasive Multimodal Neuromonitoring in Critically Ill Mechanically Ventilated COVID-19 Patients | Battaglini, D. Santori, G. Chandraptham, K. Iannuzzi, F. Bastianello, M. Tarantino, F. Ball, L. Giacobbe, D. R. Vena, A. Bassetti, M. Inglese, M. Uccelli, A. Rocco, P. R. M. Patroniti, N. Brunetti, I. Pelosi, P. Robba, C. | Front Neurol | 2020 |
Covid-19 |
| Association between plasma tau and postoperative delirium incidence and severity: a prospective observational study | Ballweg, T. White, M. Parker, M. Casey, C. Bo, A. Farahbakhsh, Z. Kayser, A. Blair, A. Lindroth, H. Pearce, R. A. Blennow, K. Zetterberg, H. Lennertz, R. Sanders, R. D. | Br J Anaesth | 2020 |
biomarker |