What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) for the diagnosis of delirium in adults in critical care settings
- Authors
- Miranda, F. Gonzalez, F. Plana, M. N. Zamora, J. Quinn, T. J. Seron, P.
- Year
- 2023
- Journal
- Cochrane Database Syst Rev
- Abstract
BACKGROUND: Delirium is an underdiagnosed clinical syndrome typified by an acute alteration of mental state. It is an important problem in critical care and intensive care units (ICU) due to its high prevalence and its association with adverse outcomes. Delirium is a very distressing condition for patients, with a huge impact on their well-being. Diagnosis of delirium in the critical care setting is challenging. This is especially true for patients who are mechanically ventilated and are therefore unable to engage in a verbal interview. The Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) is a tool specifically designed to assess for delirium in the context of ICU patients, including those on mechanical ventilation. CAM-ICU can be administered by non-specialists to give a dichotomous delirium present/absent result. OBJECTIVES: To determine the diagnostic accuracy of the CAM-ICU for the diagnosis of delirium in adult patients in critical care units. SEARCH METHODS: We searched MEDLINE (Ovid SP, 1946 to 8 July 2022), Embase (Ovid SP, 1982 to 8 July 2022), Web of Science Core Collection (ISI Web of Knowledge, 1945 to 8 July 2022), PsycINFO (Ovid SP, 1806 to 8 July 2022), and LILACS (BIREME, 1982 to 8 July 2022). We checked the reference lists of included studies and other resources for additional potentially relevant studies. We also searched the Health Technology Assessment database, the Cochrane Library, Aggressive Research Intelligence Facility database, WHO ICTRP, ClinicalTrials.gov, and websites of scientific associations to access any annual meetings and abstracts of conference proceedings in the field. SELECTION CRITERIA: We included diagnostic studies enrolling adult ICU patients assessed using the CAM-ICU tool, regardless of language or publication status and reporting sufficient data on delirium diagnosis for the construction of 2 x 2 tables. Eligible studies evaluated the diagnostic performance of the CAM-ICU versus a clinical reference standard based on any iteration of the Diagnostic and Statistical Manual of Mental Disorders (DSM) criteria applied by a clinical expert. DATA COLLECTION AND ANALYSIS: Two review authors independently selected and collated study data. We assessed the methodological quality of studies using the QUADAS-2 tool. We used two univariate fixed-effect or random-effects models to determine summary estimates of sensitivity and specificity. We performed sensitivity analyses that excluded studies considered to be at high risk of bias and high concerns in applicability, due mainly to the target population included (e.g. patients with traumatic brain injury). We also investigated potential sources of heterogeneity, assessing the effect of reference standard diagnosis and proportion of patients ventilated. MAIN RESULTS: We included 25 studies (2817 participants). The mean age of participants ranged from 48 to 69 years; 15 of the studies included critical care units admitting mixed populations (e.g. medical, trauma, surgery patients). The percentage of patients receiving mechanical ventilation ranged from 11.8% to 100%. The prevalence of delirium in the studies included ranged from 12.5% to 83.9%. Presence of delirium was determined by the application of DSM-IV criteria in 13 out of 25 included studies. We assessed 13 studies as at low risk of bias and low applicability concerns for all QUADAS-2 domains. The most common issue of concern was flow and timing of the tests, followed by patient selection. Overall, we estimated a pooled sensitivity of 0.78 (95% confidence interval (CI) 0.72 to 0.83) and a pooled specificity of 0.95 (95% CI 0.92 to 0.97). Sensitivity analysis restricted to studies at low risk of bias and without any applicability concerns (n = 13 studies) gave similar summary accuracy indices (sensitivity 0.80 (95% CI 0.72 to 0.86), specificity 0.95 (95% CI 0.93 to 0.97)). Subgroup analyses based on diagnostic assessment found summary estimates of sensitivity and specificity for studies using DSM-IV of 0.79 (95% CI 0.72 to 0.85) and 0.94 (95% CI 0.90 to 0.96). For studies that used DSM-5 criteria, summary estimates of sensitivity and specificity were 0.75 (95% CI 0.67 to 0.82) and 0.98 (95% CI 0.95 to 0.99). DSM criteria had no significant effect on sensitivity (P = 0.421), but the specificity for detection of delirium was higher when DSM-5 criteria were used (P = 0.024). The relative specificity comparing DSM-5 versus DSM-IV criteria was 1.05 (95% CI 1.02 to 1.08). Summary estimates of sensitivity and specificity for studies recruiting < 100% of patients with mechanical ventilation were 0.81 (95% CI 0.75 to 0.85) and 0.95 (95% CI 0.91 to 0.98). For studies that exclusively recruited patients with mechanical ventilation, summary estimates of sensitivity and specificity were 0.91 (95% CI 0.76 to 0.97) and 0.98 (95% CI 0.92 to 0.99). Although there was a suggestion of differential performance of CAM-ICU in ventilated patients, the differences were not significant in sensitivity (P = 0.316) or in specificity (P = 0.493). AUTHORS’ CONCLUSIONS: The CAM-ICU tool may have a role in the early identification of delirium, in adult patients hospitalized in intensive care units, including those on mechanical ventilation, when non-specialized, properly trained clinical personnel apply the CAM-ICU. The test is most useful for exclusion of delirium. The test may miss a proportion of patients with incident delirium, therefore in situations where detection of all delirium cases is desirable, it may be best to repeat the test or combine CAM-ICU with another assessment. Future studies should compare different screening tests proposed for bedside assessment of delirium, as this approach will reveal which tool yields superior accuracy. In addition, future studies should consider and report the flow and timing of the tests and clearly report key characteristics related to patient selection. Finally, future research should focus on the impact of CAM-ICU screening on patient outcomes.
- PMID
PMID: 37987526
- Keywords
Adult
Humans
Middle Aged
Aged
*Intensive Care Units
Sensitivity and Specificity
*Delirium/diagnosis
Critical Care
- Page(s)
- Volume
- Issue
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| Patterns of Potentially Inappropriate Bladder Antimuscarinic Use in People with Dementia: A Retrospective Cohort Study | Green, A. R. Segal, J. Boyd, C. M. Huang, J. Roth, D. L. | Drugs Real World Outcomes | 2020 | |
| Incidence, determinants and consequences of delirium in older patients after transcatheter aortic valve implantation | Goudzwaard, J. A. de Ronde-Tillmans, Mjag de Jager, T. A. J. Lenzen, M. J. Nuis, R. J. van Mieghem, N. M. Daemen, J. de Jaegere, P. P. T. Mattace-Raso, F. U. S. | Age Ageing | 2020 |
aortic stenosis |
| Neuromonitoring of delirium with quantitative pupillometry in sedated mechanically ventilated critically ill patients | Favre, E. Bernini, A. Morelli, P. Pasquier, J. Miroz, J. P. Abed-Maillard, S. Ben-Hamouda, N. Oddo, M. | Crit Care | 2020 |
Cholinergic |
| Cognitive Outcomes of Long-term Benzodiazepine and Related Drug (BDZR) Use in People Living With Mild to Moderate Alzheimer's Disease: Results From NILVAD | Dyer, A. H. Murphy, C. Lawlor, B. Kennelly, S. P. | J Am Med Dir Assoc | 2020 |
Dementia |
| 'Nonagenarians' with a hip fracture: is a different orthogeriatric treatment strategy necessary? | de Groot, R. Nijmeijer, W. S. Folbert, E. C. Vollenbroek-Hutten, M. M. R. Hegeman, J. H. | Arch Osteoporos | 2020 |
Frail elderly |
| Comparison of single minimum dose administration of dexmedetomidine and midazolam for prevention of emergence delirium in children: a randomized controlled trial | Cho, E. A. Cha, Y. B. Shim, J. G. Ahn, J. H. Lee, S. H. Ryu, K. H. | J Anesth | 2020 |
Dexmedetomidine |
| Innovative care models across settings: Providing nursing care to older adults | Cacchione, P. Z. | Geriatr Nurs | 2020 |
Evercare/Optum |
| Is the bispectral index monitoring protective against postoperative cognitive decline? A systematic review with meta-analysis | Bocskai, T. Kovacs, M. Szakacs, Z. Gede, N. Hegyi, P. Varga, G. Pap, I. Toth, I. Revesz, P. Szanyi, I. Nemeth, A. Gerlinger, I. Karadi, K. Lujber, L. | PLoS One | 2020 |
Anesthesia |
| Postanesthesia care unit delirium following robot-assisted vs open retropubic radical prostatectomy: A prospective observational study | Beck, S. Hoop, D. Ragab, H. Rademacher, C. Messner-Schmitt, A. von Breunig, F. Haese, A. Graefen, M. Zollner, C. Fischer, M. | Int J Med Robot | 2020 |
Trendelenburg position |
| The impact of Hospital Elder Life Program interventions, on 30-day readmission Rates of older hospitalized patients | Zachary, W. Kirupananthan, A. Cotter, S. Barbara, G. H. Cooke, R. C., 3rd Sipho, M. | Arch Gerontol Geriatr | 2020 |
Cost savings |
| Prevalence and risk factors for postoperative delirium in patients with colorectal carcinoma: a systematic review and meta-analysis | Yang, Z. Wang, X. F. Yang, L. F. Fang, C. Gu, X. K. Guo, H. W. | Int J Colorectal Dis | 2020 |
Coloretal cancer |
| Incidence, risk factors, and outcomes for sepsis-associated delirium in patients with mechanical ventilation: A sub-analysis of a multicenter randomized controlled trial | Yamamoto, T. Mizobata, Y. Kawazoe, Y. Miyamoto, K. Ohta, Y. Morimoto, T. Yamamura, H. | Journal of Critical Care | 2020 |
fentanyl |
| Effects of different BP management strategies on postoperative delirium in elderly patients undergoing hip replacement: A single center randomized controlled trial | Xu, X. Hu, X. Wu, Y. Li, Y. Zhang, Y. Zhang, M. Yang, Q. | J Clin Anesth | 2020 |
Blood pressure |
| Preoperative prognostic nutritional index predicts postoperative delirium in elderly patients after hip fracture surgery | Xing, H. Xiang, D. Li, Y. Ji, X. Xie, G. | Psychogeriatrics | 2020 |
elderly |
| The effects of early femoral nerve block intervention on preoperative pain management and incidence of postoperative delirium geriatric patients undergoing trochanteric femur fracture surgery: A randomized controlled trial | Uysal, A. I. Altiparmak, B. Yasar, E. Turan, M. Canbek, U. Yilmaz, N. Gumus Demirbilek, S. | Ulus Travma Acil Cerrahi Derg | 2020 | |
| A smartphone-based test for the assessment of attention deficits in delirium: A case-control diagnostic test accuracy study in older hospitalised patients | Tieges, Z. Stott, D. J. Shaw, R. Tang, E. Rutter, L. M. Nouzova, E. Duncan, N. Clarke, C. Weir, C. J. Assi, V. Ensor, H. Barnett, J. H. Evans, J. Green, S. Hendry, K. Thomson, M. McKeever, J. Middleton, D. G. Parks, S. Walsh, T. Weir, A. J. Wilson, E. Qua | PLoS One | 2020 | |
| A 'real-world' analysis of risk factors for post liver transplant delirium and the effect on length of stay | Tavabie, O. D. Colwill, M. Adamson, R. McPhail, M. J. W. Bernal, W. Jassem, W. Prachialias, A. Heneghan, M. Aluvihare, V. R. Agarwal, K. | Eur J Gastroenterol Hepatol | 2020 | |
| Intraoperative hypotension and delirium in patients with hip fracture | Tantardini, V. Roca, F. Bahri, O. Compere, V. Dujardin, F. Chassagne, P. | Geriatr Psychol Neuropsychiatr Vieil | 2020 |
anaesthesia |
| Evaluation of emergence agitation after general anaesthesia in rhinoplasty patients: Inhalation anaesthesia versus total intravenous anaesthesia | Talih, G. Yüksek, A. Şahin, E. | American Journal of Otolaryngology - Head and Neck Medicine and Surgery | 2020 |
adult |
| Implementation of a multiprofessional, multicomponent delirium management guideline in two intensive care units, and its effect on patient outcomes and nurse workload: a pre-post design retrospective cohort study | Schubert, M. Bettex, D. Steiger, P. Schurch, R. Haller, A. Bogdanovic, J. Garcia Nunez, D. Schwarz, U. Siegemund, M. | Swiss Med Wkly | 2020 | |
| Cerebrospinal Fluid Levels of Interleukin-8 in Delirium, Dementia, and Cognitively Healthy Patients | Sajjad, M. U. Blennow, K. Knapskog, A. B. Idland, A. V. Chaudhry, F. A. Wyller, T. B. Zetterberg, H. Watne, L. O. | J Alzheimers Dis | 2020 |
Alzheimer’s disease |
| Prehospital Anticholinergic Burden Is Associated With Delirium but Not With Mortality in a Population of Acutely Ill Medical Patients | Rigor, J. Rueff Rato, I. Ferreira, P. M. Pereira, R. Ribeiro, C. Teixeira, D. Mesquita Oliveira, P. Silva, A. M. Pereira, S. Costa, I. Ferreira, P. Sequeira, M. Monteiro-Soares, M. Martins-Mendes, D. | J Am Med Dir Assoc | 2020 |
Anticholinergic |
| Impact of Vitamin C and Thiamine Administration on Delirium-Free Days in Patients with Septic Shock | Park, J. E. Shin, T. G. Jo, I. J. Jeon, K. Suh, G. Y. Park, M. Won, H. Chung, C. R. Hwang, S. Y. | J Clin Med | 2020 |
delirium |
| Evaluation of an updated sedation protocol to reduce benzodiazepines in a pediatric intensive care unit | Michel, J. Hofbeck, M. Peper, A. K. Kumpf, M. Neunhoeffer, F. | Curr Med Res Opin | 2020 |
Cardiac surgery |
| A qualitative exploration of the views of patients and their relatives regarding interventions to minimize the distress related to postoperative delirium | Meilak, C. Biswell, E. Willis, R. Partridge, J. Dhesi, J. | Int J Geriatr Psychiatry | 2020 |
aged |
| Incidence and risk factors of postoperative delirium in elderly patients undergoing urological surgery: A multi-institutional prospective study | Matsuki, M. Tanaka, T. Takahashi, A. Inoue, R. Hotta, H. Itoh, N. Taguchi, K. Kato, R. Kobayashi, K. Masumori, N. | Int J Urol | 2020 |
elderly patients |
| Still Predicting Delirium After All These Years | Marcantonio, ER | Anesth Analg | 2020 | |
| Ketamine sedation in mechanically ventilated patients: A systematic review and meta-analysis | Manasco, A. T. Stephens, R. J. Yaeger, L. H. Roberts, B. W. Fuller, B. M. | Journal of Critical Care | 2020 |
fentanyl |
| A Study of the Psychometric Properties of the “Stanford Proxy Test for Delirium” (S-PTD): A New Screening Tool for the Detection of Delirium | Maldonado, J. R. Sher, Y. I. Benitez-Lopez, M. A. Savant, V. Garcia, R. Ament, A. De Guzman, E. | Psychosomatics | 2020 |
adult |
| Risk factors for postoperative delirium after colorectal surgery: a systematic review and meta-analysis | Lee, S. H. Lim, S. W. | Int J Colorectal Dis | 2020 |
Colorectal surgery |
| Results from a double blinded, randomized, placebo-controlled, feasibility trial of melatonin for the treatment of delirium in older medical inpatients | Lange, P. W. Clayton-Chubb, D. I. Watson, R. Maier, A. B. | Intern Med J | 2020 |
Delirium |
| Risk factors and outcomes among delirium subtypes in adult ICUs: A systematic review | Krewulak, K. D. Stelfox, H. T. Ely, E. W. Fiest, K. M. | J Crit Care | 2020 |
Critical care |
| Survey of analgesia and sedation in pediatric intensive care units in Japan | Koizumi, T. Kurosawa, H. | Pediatr Int | 2020 |
analgesia |
| Association of neuronal repair biomarkers with delirium among survivors of critical illness | Hayhurst, C. J. Patel, M. B. McNeil, J. B. Girard, T. D. Brummel, N. E. Thompson, J. L. Chandrasekhar, R. Ware, L. B. Pandharipande, P. P. Ely, E. W. Hughes, C. G. | Journal of Critical Care | 2020 |
NCT00392795 |
| Dexmedetomidine's Relationship to Delirium in Patients Undergoing Cardiac Surgery: A Systematic Review | Halpin, E. Inch, H. O'Neill, M. | Crit Care Nurs Q | 2020 | |
| Management of delirium at an academic medical center: Plans for antipsychotic prescribing upon discharge | Halavonich, L. Robert, S. McGraw, D. Weeda, E. Mullinax, K. Bass, B. | Ment Health Clin | 2020 |
antipsychotic |
| Association Between Level of Arousal and 30-Day Survival in Acutely Ill Older Adults | Garcez, F. B. Jacob-Filho, W. Avelino-Silva, T. J. | J Am Med Dir Assoc | 2020 |
Delirium |
| Drug therapy for delirium in terminally ill adults | Finucane, A. M. Jones, L. Leurent, B. Sampson, E. L. Stone, P. Tookman, A. Candy, B. | Cochrane Database Syst Rev | 2020 | |
| Delirium in patients with hip fracture is associated with increased heart rate variability | Ernst, G. Watne, L. O. Rostrup, M. Neerland, B. E. | Aging Clin Exp Res | 2020 |
Autonomic nervous system |
| Risk factors for delirium after esophagectomy | Dezube, A. R. Bravo-Iniguez, C. E. Yelamanchili, N. De Leon, L. E. Tarascio, J. Jaklitsch, M. T. Wee, J. O. | J Surg Oncol | 2020 |
delirium |
| Delirium in a Tertiary PICU: Risk Factors and Outcomes | Dervan, L. A. Di Gennaro, J. L. Farris, R. W. D. Watson, R. S. | Pediatr Crit Care Med | 2020 | |
| Validity and Reliability of the Brazilian Portuguese Version of the Pediatric Confusion Assessment Method for the ICU | de Castro, R. E. V. Prata-Barbosa, A. de Magalhaes-Barbosa, M. C. Cunha, Ajlad Cheniaux, E. Smith, H. A. B. | Pediatr Crit Care Med | 2020 | |
| Outcomes for patients with delirium receiving hospital-in-the-home treatment: An Australian perspective | Chia, J. Eeles, E. M. Tattam, K. Yerkovich, S. | Australas J Ageing | 2020 |
delirium |
| A software to prevent delirium in hospitalised older adults: development and feasibility assessment | Alvarez, E. A. Garrido, M. Ponce, D. P. Pizarro, G. Cordova, A. A. Vera, F. Ruiz, R. Fernandez, R. Velasquez, J. D. Tobar, E. Salech, F. | Age Ageing | 2020 |
delirium |
| Cholinesterase alterations in delirium after cardiosurgery: a German monocentric prospective study | Adam, E. H. Haas, V. Lindau, S. Zacharowski, K. Scheller, B. | BMJ Open | 2020 |
acetylcholinesterase |
| Cornell Assessment of Pediatric Delirium: a valid, rapid, observational tool for screening delirium in the PICU* | Traube, C. Silver, G. Kearney, J. Patel, A. Atkinson, T. M. Yoon, M. J. Halpert, S. Augenstein, J. Sickles, L. E. Li, C. Greenwald, B. | Crit Care Med | 2014 |
Adolescent |
| The Preschool Confusion Assessment Method for the ICU: Valid and Reliable Delirium Monitoring for Critically Ill Infants and Children | Smith, H. A. Gangopadhyay, M. Goben, C. M. Jacobowski, N. L. Chestnut, M. H. Savage, S. Rutherford, M. T. Denton, D. Thompson, J. L. Chandrasekhar, R. Acton, M. Newman, J. Noori, H. P. Terrell, M. K. Williams, S. R. Griffith, K. Cooper, T. J. Ely, E. W. F | Crit Care Med | 2016 |
Child, Preschool |
| Diagnosing delirium in critically ill children: Validity and reliability of the Pediatric Confusion Assessment Method for the Intensive Care Unit | Smith, H. A. Boyd, J. Fuchs, D. C. Melvin, K. Berry, P. Shintani, A. Eden, S. K. Terrell, M. K. Boswell, T. Wolfram, K. Sopfe, J. Barr, F. E. Pandharipande, P. P. Ely, E. W. | Crit Care Med | 2011 |
Child |
| Development and psychometric evaluation of the pediatric anesthesia emergence delirium scale | Sikich, N. Lerman, J. | Anesthesiology | 2004 |
*Anesthesia Recovery Period |
| From Pediatrics to Geriatrics: Toward a Unified Standardized Screening Tool for Delirium: A Thought Experiment | Schieveld, J. N. van Zwieten, J. J. | Crit Care Med | 2016 |
Adult |
| Diagnostic considerations regarding pediatric delirium: a review and a proposal for an algorithm for pediatric intensive care units | Schieveld, J. N. van der Valk, J. A. Smeets, I. Berghmans, E. Wassenberg, R. Leroy, P. L. Vos, G. D. van Os, J. | Intensive Care Med | 2009 |
Age Factors |
| On the utility of diagnostic instruments for pediatric delirium in critical illness: an evaluation of the Pediatric Anesthesia Emergence Delirium Scale, the Delirium Rating Scale 88, and the Delirium Rating Scale-Revised R-98 | Janssen, N. J. Tan, E. Y. Staal, M. Janssen, E. P. Leroy, P. L. Lousberg, R. van Os, J. Schieveld, J. N. | Intensive Care Med | 2011 |
*Anesthesia Recovery Period |
| Validation of the SOS-PD scale for assessment of pediatric delirium: a multicenter study | Ista, E. van Beusekom, B. van Rosmalen, J. Kneyber, M. C. J. Lemson, J. Brouwers, A. Dieleman, G. C. Dierckx, B. de Hoog, M. Tibboel, D. van Dijk, M. | Crit Care | 2018 |
Adolescent |
| Sophia Observation withdrawal Symptoms-Paediatric Delirium scale: A tool for early screening of delirium in the PICU | Ista, E. Te Beest, H. van Rosmalen, J. de Hoog, M. Tibboel, D. van Beusekom, B. van Dijk, M. | Aust Crit Care | 2018 |
Adolescent |
| Psychometric evaluation of the Sophia Observation withdrawal symptoms scale in critically ill children | Ista, E. de Hoog, M. Tibboel, D. Duivenvoorden, H. J. van Dijk, M. | Pediatr Crit Care Med | 2013 |
Adolescent |
| Clinical recommendations for pain, sedation, withdrawal and delirium assessment in critically ill infants and children: an ESPNIC position statement for healthcare professionals | Harris, J. Ramelet, A. S. van Dijk, M. Pokorna, P. Wielenga, J. Tume, L. Tibboel, D. Ista, E. | Intensive Care Med | 2016 |
Child |
| Assessment scales for delirium: A review | Grover, S. Kate, N. | World J Psychiatry | 2012 |
Cognition |
| Diagnostic accuracy of delirium diagnosis in pediatric intensive care: a systematic review | Daoud, A. Duff, J. P. Joffe, A. R. Alberta Sepsis, Network | Crit Care | 2014 |
Anesthesia/adverse effects |
| Diagnostic accuracy of delirium diagnosis in pediatric intensive care: a systematic review | Daoud, A. Duff, J. P. Joffe, A. R. Alberta Sepsis, Network | Crit Care | 2014 |
Anesthesia/adverse effects |
| Delirium is prevalent in older hospital inpatients and associated with adverse outcomes: Results of a prospective multi-centre study on World Delirium Awareness Day | Welch, C. McCluskey, L. Wilson, D. Chapman, G. E. Jackson, T. A. Treml, J. Davis, D. Cunningham, E. Copeland, C. Quinn, T. Pinkney, T. Mahida, R. Nightingale, P. Richardson, S. Todd, O. Willott, R. Torsney, K. Ni Lochlainn, M. Giridharan, K. Cox, N. Masol | BMC Medicine | 2019 |
adult |
| Olanzapine Versus Haloperidol for Treatment of Delirium in Patients with Advanced Cancer: A Phase III Randomized Clinical Trial | van der Vorst, Mjdl Neefjes, E. C. W. Boddaert, M. S. A. Verdegaal, Batt Beeker, A. Teunissen, S. C. C. Beekman, A. T. F. Wilschut, J. A. Berkhof, J. Zuurmond, W. W. A. Verheul, H. M. W. | Oncologist | 2019 |
Advanced cancer |
| Diverging Awareness of Postoperative Delirium and Cognitive Dysfunction in German Health Care Providers | Sturm, H. Wildermuth, R. Stolz, R. Bertram, L. Eschweiler, G. W. Thomas, C. Rapp, M. Joos, S. | Clin Interv Aging | 2019 |
Pocd |
| An evaluation of the Danish version of the Pediatric Anesthesia Emergence Delirium scale | Simonsen, B. Y. Skovby, P. Lisby, M. | Acta Anaesthesiol Scand | 2019 | |
| Incidence and Risk Factors for Delirium in Elderly Patients with Critical Limb Ischaemia | Roijers, J. P. Rakke, Y. S. Hopmans, C. J. Buimer, M. G. de Groot, H. G. W. Ho, G. H. Veen, E. J. Mulder, P. G. H. van der Laan, L. | Eur J Vasc Endovasc Surg | 2019 |
Critical limb ischaemia |
| Initiative for Prevention and Early Identification of Delirium in Medical-Surgical Units: Lessons Learned in the Past Five Years | Rohatgi, N. Weng, Y. Bentley, J. Lansberg, M. G. Shepard, J. Mazur, D. Ahuja, N. Hopkins, J. | Am J Med | 2019 |
Delirium |
| Elevation of Preoperative Ammonia Level Is Not Associated With the Incidence of Postoperative Delirium in Patients with Liver Transplantation: A Propensity Score Matching Analysis | Ri, H. S. Choi, Y. J. Park, J. Y. Jin, S. J. Lee, Y. S. Son, J. M. Yoon, S. Z. Shin, H. W. Choi, B. H. Lee, T. B. | Transplant Proc | 2019 | |
| Fluctuations of consciousness after stroke: Associations with the confusion assessment method for the intensive care unit (CAM-ICU) and potential undetected delirium | Reznik, M. E. Daiello, L. A. Thompson, B. B. Wendell, L. C. Mahta, A. Potter, N. S. Yaghi, S. Levy, M. M. Fehnel, C. R. Furie, K. L. Jones, R. N. | J Crit Care | 2019 |
Consciousness |
| Postoperative serum albumin decrease independently predicts delirium in elderly subjects after total joint arthroplasty | Qi, J. Liu, C. Chen, L. Chen, J. | Curr Pharm Des | 2019 |
Postoperative delirium |
| Dexmedetomidine versus propofol sedation in reducing delirium among older adults in the ICU: A systematic review and meta-analysis | Pereira, J. V. Sanjanwala, R. M. Mohammed, M. K. Le, M. L. Arora, R. C. | Eur J Anaesthesiol | 2019 | |
| Delirium Rates in Advanced Cancer Patients Admitted to Different Palliative Care Settings: Does It Make the Difference? | Pallotti, M. C. Lopez-Fidalgo Ph, D. J. Biasco, G. Celin, D. Centeno, C. Paragona, M. Moroni, M. Noguera, A. | J Palliat Med | 2019 |
cancer patients |
| Randomized Controlled Trial of Enhanced Recovery Program Dedicated to Elderly Patients after Colorectal Surgery | Ostermann, S. Morel, P. Chalé, J. J. Bucher, P. Konrad, B. Meier, R. P. H. Ris, F. Schiffer, E. R. C. | Diseases of the Colon and Rectum | 2019 |
NCT01646190 |
| The effect of ketamine on emergence agitation in children: A systematic review and meta-analysis | Ng, K. T. Sarode, D. Lai, Y. S. Teoh, W. Y. Wang, C. Y. | Paediatr Anaesth | 2019 |
emergence agitation |
| BIS index monitoring and perioperative neurocognitive disorders in older adults: a systematic review and meta-analysis | Miao, M. Xu, Y. Sun, M. Chang, E. Cong, X. Zhang, J. | Aging Clin Exp Res | 2019 |
Bispectral index |
| Plasma biomarkers of inflammation, coagulation, and brain injury as predictors of delirium duration in older hospitalized patients | McNeil, J. B. Hughes, C. G. Girard, T. Ware, L. B. Ely, E. W. Chandrasekhar, R. Han, J. H. | PLoS One | 2019 | |
| Randomized controlled trial of acupuncture to prevent emergence delirium in children undergoing myringotomy tube placement | Martin, C. S. Yanez, N. D. Treggiari, M. M. Piper, L. Cusick, J. Lalwani, K. | Minerva Anestesiol | 2019 | |
| Detecting delirium in patients with acute stroke: a systematic review of test accuracy | Mansutti, I. Saiani, L. Palese, A. | BMC Neurol | 2019 |
Instruments |
| Associations of 4AT with mobility, length of stay and mortality in hospital and discharge destination among patients admitted with hip fractures | Lisk, R. Yeong, K. Enwere, P. Jenkinson, J. Robin, J. Irvin-Sellers, M. Fluck, D. Osmani, A. Sharmin, R. Sharma, P. Fry, C. H. Han, T. S. | Age Ageing | 2019 |
Nhs |
| Effectiveness of an advanced practice nurse-led delirium education and training programme | Lieow, J. L. M. Chen, F. S. M. Song, G. Tang, P. S. Kowitlawakul, Y. Mukhopadhyay, A. | Int Nurs Rev | 2019 |
Advanced Practice Nurses |
| Comparison of emergence agitation between succinylcholine and rocuronium-sugammadex in adults following closed reduction of a nasal bone fracture: A prospective randomized controlled trial | Lee, S. J. Sung, T. Y. Cho, C. K. | BMC Anesthesiology | 2019 |
adult |
| Risk factors for post-intensive care syndrome: A systematic review and meta-analysis | Lee, M. Kang, J. Jeong, Y. J. | Aust Crit Care | 2019 |
Intensive care units |
| Effect of Perioperative Low-Dose Dexmedetomidine on Postoperative Delirium After Living-Donor Liver Transplantation: A Randomized Controlled Trial | Lee, H. Yang, S. M. Chung, J. Oh, H. W. Yi, N. J. Suh, K. S. Oh, S. Y. Ryu, H. G. | Transplant Proc | 2019 | |
| The Association of Perioperative Serum Lactate Levels with Postoperative Delirium in Elderly Trauma Patients | Lee, C. Lee, J. Cho, H. Song, J. Jung, H. Ma, X. Hwang, J. | BioMed Research International | 2019 |
lactic acid |
| Frailty defined by 19 items as a predictor of short-term functional recovery in patients with hip fracture | Inoue, T. Misu, S. Tanaka, T. Kakehi, T. Kakiuchi, M. Chuman, Y. Ono, R. | Injury | 2019 |
aged |
| Using language descriptors to recognise delirium: a survey of clinicians and medical coders to identify delirium-suggestive words | Holmes, N. E. Amjad, S. Young, M. Berlowitz, D. J. Bellomo, R. | Crit Care Resusc | 2019 |
*Clinical Coding |
| Diagnostic test accuracy meta-analysis of PRE-DELIRIC (PREdiction of DELIRium in ICu patients): A delirium prediction model in intensive care practice | Ho, M. H. Chen, K. H. Montayre, J. Liu, M. F. Chang, C. C. Traynor, V. Shen Hsiao, S. T. Chang, H. R. Chiu, H. Y. | Intensive Crit Care Nurs | 2019 |
Delirium |
| Delirium management: Let's get physical? A systematic review and meta-analysis | Haley, M. N. Casey, P. Kane, R. Y. Darzins, P. Lawler, K. | Australas J Ageing | 2019 |
delirium |
| Delirium post-cardiac surgery: Incidence and associated factors | Habeeb-Allah, A. Alshraideh, J. A. | Nurs Crit Care | 2019 |
associated factors |
| EEG Correlates of Delirium in Children and Young Adults With CD19-Directed CAR T Cell Treatment-Related Neurotoxicity | Gust, J. Annesley, C. E. Gardner, R. A. Bozarth, X. | J Clin Neurophysiol | 2019 | |
| Process of implementing and delivering the Prevention of Delirium system of care: a mixed method preliminary study | Godfrey, M. Green, J. Smith, J. Cheater, F. Inouye, S. K. Hurst, K. Young, J. | BMC Geriatr | 2019 |
Delirium prevention |
| Association between postoperative delirium and postoperative cerebral oxygen desaturation in older patients after cardiac surgery | Eertmans, W. De Deyne, C. Genbrugge, C. Marcus, B. Bouneb, S. Beran, M. Fret, T. Gutermann, H. Boer, W. Vander Laenen, M. Heylen, R. Mesotten, D. Vanelderen, P. Jans, F. | Br J Anaesth | 2019 |
cardiac surgery |
| Frailty and hospital outcomes within a low socioeconomic population | Clark, S. Shaw, C. Padayachee, A. Howard, S. Hay, K. Frakking, T. T. | QJM | 2019 | |
| Perioperative outcomes in geriatric patients undergoing hip fracture surgery with different anesthesia techniques: A systematic review and meta-analysis | Chen, D. X. Yang, L. Ding, L. Li, S. Y. Qi, Y. N. Li, Q. | Medicine | 2019 |
Aged |
| Postoperative delirium is associated with increased plasma neurofilament light | Casey, C. P. Lindroth, H. Mohanty, R. Farahbakhsh, Z. Ballweg, T. Twadell, S. Miller, S. Krause, B. Prabhakaran, V. Blennow, K. Zetterberg, H. Sanders, R. D. | Brain | 2019 |
adult |
| Differential clinical characteristics, management and outcome of delirium among ward compared with intensive care unit patients | Canet, E. Amjad, S. Robbins, R. Lewis, J. Matalanis, M. Jones, D. Bellomo, R. | Intern Med J | 2019 |
*agitation |
| An Evaluation of Risperidone Dosing for Pediatric Delirium in Children Less Than or Equal to 2 Years of Age | Campbell, C. T. Grey, E. Munoz-Pareja, J. Manasco, K. B. | Annals of Pharmacotherapy | 2019 |
article |
| Inpatient Rehabilitation Delirium Screening: Impact on Acute Care Transfers and Functional Outcomes | Bushi, S. Barrett, A. M. Oh-Park, M. | PMR | 2019 |
Acute Care Transfer |
| Routine Management of Postoperative Delirium Outside the ICU: Results of an International Survey among Anaesthesiologists | Bilotta, F. Weiss, B. Neuner, B. Kramer, S. Aldecoa, C. Bettelli, G. Sanders, R. D. Delp, S. M. Spies, C. D. | Acta Anaesthesiol Scand | 2019 |
Postoperative delirium |
| Impact of delirium on short-term outcomes in hip fracture patients under a program of approach to delirium | Bielza, R. Zambrana, F. Fernandez de la Puente, E. Sanjurjo, J. Andreu, C. Thuissard, I. J. Gomez Cerezo, J. | Geriatr Gerontol Int | 2019 |
delirium |
| Outcome Differences by Delirium Motor Subtype in Patients with Ischemic Stroke | Yang, H. W. Lee, M. Shin, J. W. Jeong, H. S. Kim, J. Kim, J. L. | Psychiatry Investig | 2019 |
Delirium |
| Serial Ottawa 3DY assessments to detect delirium in older emergency department community dwellers | Yadav, K. Boucher, V. Carmichael, P. H. Voyer, P. Eagles, D. Pelletier, M. Gouin, E. Daoust, R. Vu, T. T. M. Berthelot, S. Emond, M. | Age Ageing | 2019 |
delirium |