What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Prevention of dexmedetomidine on postoperative delirium and early postoperative cognitive dysfunction in elderly patients undergoing hepatic lobectomy
- Authors
- Tang, Y. Wang, Y. Kong, G. Zhao, Y. Wei, L. Liu, J.
- Year
- 2022
- Journal
- Zhong Nan Da Xue Xue Bao Yi Xue Ban
- Abstract
OBJECTIVES: Postoperative delirium (POD) and postoperative cognitive dysfunction (POCD) are common operative neurocognitive disorders, which places a heavy burden on patients, families and society. Therefore, it is very important to search for preventive drugs. Previous studies have demonstrated that perioperative use of dexmedetomidine resulted in a decrease the incidence of POD and POCD. But the specific effect of dexmedetomidine on elderly patients undergoing hepatic lobectomy and its potential mechanism are not clear. This study aims to evaluate the efficacy of intraoperative use of dexmedetomidine on preventing POD and POCD in elderly patients undergoing hepatic lobectomy and the influence on the balance between proinflammation and anti-inflammation. METHODS: This trial was designed as a single-center, prospective, randomized, controlled study. One hundred and twenty hospitalized patients from January 2019 to December 2020, aged 60-80 years old with American Society of Anesthesiologists (ASA) II-III and scheduled for hepatic lobectomy, were randomly allocated into 3 groups (n=40) using a random number table: A C group, a Dex1 group, and a Dex2 group. After anesthesia induction, saline in the C group, dexmedetomidine [0.3 μg/(kg·h)] in the Dex1 group, and dexmedetomidine [0.6 μg/(kg·h)] in the Dex2 group were infused until the end of operation. The incidences of hypotension and bradycardia were compared among the 3 groups. Confusion Assessment Method (CAM) for assessing POD and Mini Mental State Examination (MMSE) for evaluating POCD were recorded and venous blood samples were obtained for the determination of neuron specific enolase (NSE), TNF-α, IL-1β, and IL-10 at the different time below: the time before anesthesia (T0), and the first day (T1), the third day (T2), the fifth day (T3), and the seventh day (T4) after operation. RESULTS: Compared with the C group, the incidences of bradycardia in the Dex1 group or the Dex2 group increased (both P<0.05) and there was no difference in hypotension in the Dex1 group or the Dex2 group (both P>0.05). The incidences of POD in the C group, the Dex1 group, and the Dex2 group were 22.5%, 5.0%, and 7.5%, respectively. The incidences of POD in the Dex1 group or the Dex2 group declined significantly as compared to the C group (both P<0.05). However, there is no difference in the incidence of POD between the Dex1 group and the Dex2 group (P>0.05). The incidences of POCD in the C group, the Dex1 group, and the Dex2 group were 30.0%, 12.5%, and 10.0%, respectively. The incidences of POCD in the Dex1 group and the Dex2 group declined significantly as compared to the C group (both P<0.05). And no obvious difference was seen in the incidence of POCD in the Dex1 group and the Dex2 group (P>0.05). Compared with the C group, the level of TNF-α and IL-1β decreased and the level of IL-10 increased at each time points (from T1 to T4) in the Dex1 group and the Dex2 group (all P<0.05). Compared with the Dex1 group, the level of IL-1β at T2 and IL-10 from T1 to T3 elevated in the Dex2 group (all P<0.05). Compared with the T0, the concentrations of NSE in C group at each time points (from T1 to T4) and in the Dex1 group and the Dex2 group from T1 to T3 increased (all P<0.05). Compared with the C group, the level of NSE decreased from T1 to T4 in the Dex1 group and the Dex2 group (all P<0.05). CONCLUSIONS: Intraoperative dexmedetomidine infusion can reduce the incidence of POCD and POD in elderly patients undergoing hepatic lobectomy, and the protective mechanism appears to involve the down-regulation of TNF-α and IL-1β and upregulation of IL-10 expression, which lead to rebalance between proinflammation and anti-inflammation.
- PMID
- Keywords
Aged
Aged, 80 and over
Bradycardia
*Cognitive Dysfunction/etiology/prevention & control
*Delirium/drug therapy/epidemiology/prevention & control
*Dexmedetomidine/therapeutic use
Humans
*Hypotension/complications/drug therapy
Interleukin-10
Middle Aged
*Postoperative Cognitive Complications/prevention & control
Postoperative Complications/epidemiology
Prospective Studies
Tumor Necrosis Factor-alpha
dexmedetomidine
elderly patients
hepatic lobectomy
postoperative cognitive dysfunction
postoperative delirium
- Page(s)
- Volume
- Issue
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| Delirium risk prediction models for intensive care unit patients: A systematic review | Chen, J. Yu, J. Zhang, A. | Intensive Crit Care Nurs | 2020 |
Delirium |
| The role of statins in the management of delirium: Recent advances | Chen, J. Wang, Y. Hu, X. Li, M. Xiong, K. Zhang, Z. Chen, Q. | CNS Neurol Disord Drug Targets | 2020 |
Delirium |
| Analysis of Risk Factors for Postoperative Delirium After Liver Transplantation | Chen, J. Wang, H. He, Z. Li, T. | Neuropsychiatr Dis Treat | 2020 |
ammonia |
| Analgesia and sedation in patients with ARDS | Chanques, G. Constantin, J. M. Devlin, J. W. Ely, E. W. Fraser, G. L. Gélinas, C. Girard, T. D. Guérin, C. Jabaudon, M. Jaber, S. Mehta, S. Langer, T. Murray, M. J. Pandharipande, P. Patel, B. Payen, J. F. Puntillo, K. Rochwerg, B. Shehabi, Y. Strøm, T | Intensive Care Med | 2020 |
Analgesia/methods/ standards |
| Delirium Prevention, Detection, and Treatment in Emergency Medicine Settings: A Geriatric Emergency Care Applied Research (GEAR) Network Scoping Review and Consensus Statement | Carpenter, C. R. Hammouda, N. Linton, E. A. Doering, M. Ohuabunwa, U. K. Ko, K. J. Hung, W. W. Shah, M. N. Lindquist, L. A. Biese, K. Wei, D. Hoy, L. Nerbonne, L. Hwang, U. Dresden, S. M. | Academic Emergency Medicine | 2020 |
aged |
| Geriatric emergency care applied research network cognitive impairment priorities consensus conference | Carpenter, C. R. Hammouda, N. Linton, E. Doerring, M. Ohuabunwa, U. Ko, K. Hung, W. Dresden, S. M. Shah, M. N. Lindquist, L. Biese, K. Wei, D. Hwang, U. | Academic Emergency Medicine | 2020 |
adult |
| Identifying and Responding to Delirium in Acute Stroke: Clinical Team Members' Understandings | Carin-Levy, G. Nicol, K. van Wijck, F. Mead, G. McVittie, C. | Qualitative health research | 2020 |
adult |
| Antipsychotic use in the prevention and treatment of intensive care unit delirium in pediatric patients | Capino, A. C. Thomas, A. N. Baylor, S. Hughes, K. M. Miller, J. L. Johnson, P. N. | Journal of Pediatric Pharmacology and Therapeutics | 2020 |
haloperidol |
| Screening instruments for cognitive impairment in older patients in the Emergency Department: a systematic review and meta-analysis | Calf, A. H. Pouw, M. A. van Munster, B. C. Burgerhof, J. G. M. de Rooij, S. E. Smidt, N. | Age Ageing | 2020 |
Emergency Department |
| Prevalence, Predictors, and Early Outcomes of Post-operative Delirium in Patients With Type A Aortic Dissection During Intensive Care Unit Stay | Cai, S. Zhang, X. Pan, W. Latour, J. M. Zheng, J. Zhong, J. Gao, J. Lv, M. Luo, Z. Wang, C. Zhang, Y. | Front Med (Lausanne) | 2020 |
delirium |
| Toxin-Induced Acute Delirium | Cai, A. Cai, X. | Neurol Clin | 2020 |
Anticholinergic |
| Cognitive and psychosocial outcomes of mechanically ventilated intensive care patients with and without delirium | Bulic, D. Bennett, M. Georgousopoulou, E. N. Shehabi, Y. Pham, T. Looi, J. C. L. van Haren, F. M. P. | Ann Intensive Care | 2020 |
Cognition |
| The influence of a serious game's narrative on students' attitudes and learning experiences regarding delirium: an interview study | Buijs-Spanjers, K. R. Harmsen, A. Hegge, H. H. Spook, J. E. de Rooij, S. E. Jaarsma, Dadc | BMC Med Educ | 2020 |
Delirium |
| Preoperative prognostic factors associated with postoperative delirium in older people undergoing surgery: protocol for a systematic review and individual patient data meta-analysis | Buchan, T. A. Sadeghirad, B. Schmutz, N. Goettel, N. Foroutan, F. Couban, R. Mbuagbaw, L. Dodsworth, B. T. | Syst Rev | 2020 |
Elderly |
| Impact of Therapeutic Music Listening on Intensive Care Unit Patients: A Pilot Study | Browning, S. G. Watters, R. Thomson-Smith, C. | Nurs Clin North Am | 2020 |
Aged |
| Association between delirium in the intensive care unit and subsequent neuropsychiatric disorders | Brown, K. N. Soo, A. Faris, P. Patten, S. B. Fiest, K. M. Stelfox, H. T. | Crit Care | 2020 |
Aged |
| Association of Positive Delirium Screening with Incident Dementia in Skilled Nursing Facilities | Briesacher, B. A. Koethe, B. Olivieri-Mui, B. Saczynski, J. S. Fick, D. M. Devlin, J. W. Marcantonio, E. R. | J Am Geriatr Soc | 2020 |
delirium |
| Economic Burden of Postoperative Neurocognitive Disorders Among US Medicare Patients | Boone, M. D. Sites, B. von Recklinghausen, F. M. Mueller, A. Taenzer, A. H. Shaefi, S. | JAMA Netw Open | 2020 |
Aged |
| Hospital Elder Life Program in Long-Term Care (HELP-LTC): A Cluster Randomized Controlled Trial | Boockvar, K. S. Judon, K. M. Eimicke, J. P. Teresi, J. A. Inouye, S. K. | J Am Geriatr Soc | 2020 |
delirium |
| Pain Incidence, Treatment, and Associated Symptoms in Hospitalized Persons with Dementia | Boltz, M. Resnick, B. Kuzmik, A. Mogle, J. Jones, J. R. Arendacs, R. BeLue, R. Cacchione, P. Galvin, J. E. | Pain Manag Nurs | 2020 | |
| Disparities in Physical and Psychological Symptoms in Hospitalized African American and White Persons with Dementia | Boltz, M. BeLue, R. Resnick, B. Kuzmik, A. Galik, E. Jones, J. R. Arendacs, R. Sinvani, L. Mogle, J. Galvin, J. E. | J Aging Health | 2020 |
African Americans |
| The prevalence rates and adversities of delirium: Too common and disadvantageous | Boettger, S. Zipser, C. M. Bode, L. Spiller, T. Deuel, J. Osterhoff, G. Ernst, J. Petry, H. Volbracht, J. von Känel, R. | Palliat Support Care | 2020 |
Delirium |
| Assessing delirium with nursing care instruments: Evaluation of the cognitive and associated domains | Bode, L. Fuchs, S. Gehrke, S. Ernst, J. Schubert, M. Nuñez, D. G. von Känel, R. Boettger, S. | Palliat Support Care | 2020 |
Assessment |
| Iranian Nurses Perception and Practices for Delirium Assessment in Intensive Care Units | Biyabanaki, F. Arab, M. Dehghan, M. | Indian J Crit Care Med | 2020 |
Assessment |
| How to fight against overtreatment? Example of neuroleptic prescriptions for acute delirium | Bianchi, C. Blondet, F. Aebischer, O. Méan, M. | Revue Medicale Suisse | 2020 |
neuroleptic agent |
| Clinical Presentation of COVID19 in Dementia Patients | Bianchetti, A. Rozzini, R. Guerini, F. Boffelli, S. Ranieri, P. Minelli, G. Bianchetti, L. Trabucchi, M. | Journal of Nutrition, Health and Aging | 2020 |
aged |
| Validation of two nurse-based screening tools for delirium in elderly patients in general medical wards | Bergjan, M. Zilezinski, M. Schwalbach, T. Franke, C. Erdur, H. Audebert, H. J. Hauß, A. | BMC Nurs | 2020 |
Confusion |
| Prevalence and management of delirium in intensive care units in the Netherlands: An observational multicentre study | Berger, E. Wils, E. J. Vos, P. van Santen, S. Koets, J. Slooter, A. J. C. van der Woude, M. Koopmans, M. Rinket, M. A. Hoiting, O. Hoogendoorn, E. E. Streefkerk, J. O. de Vreede, E. W. Riekerk, B. Simons, K. S. Toscano, E. Schoonderbeek, F. J. Hofstra, L. | Intensive Crit Care Nurs | 2020 |
Critically ill |
| Effect of Exogenous Melatonin Administration in Critically Ill Patients on Delirium and Sleep: A Randomized Controlled Trial | Bellapart, J. Appadurai, V. Lassig-Smith, M. Stuart, J. Zappala, C. Boots, R. | Crit Care Res Pract | 2020 | |
| Delirium, functional decline and quality of life after transcatheter aortic valve implantation: An explorative study | Beishuizen, S. J. Festen, S. Loonstra, Y. E. van der Werf, H. W. de Rooij, S. E. van Munster, B. C. | Geriatr Gerontol Int | 2020 |
activities of daily living |
| Clinical outcomes in patients admitted to hospital with cervical spine fractures or with hip fractures | Baxter, J. Lisk, R. Osmani, A. Yeong, K. Robin, J. Fluck, D. Fry, C. H. Han, T. S. | Intern Emerg Med | 2020 |
Discharge destination |
| Frequency and Implications of Complications in the ICU After Status Epilepticus: No Calm After the Storm | Baumann, S. M. Semmlack, S. De Marchis, G. M. Hunziker, S. Rüegg, S. Marsch, S. Sutter, R. | Critical care medicine | 2020 |
adult |
| Neurological Complications and Noninvasive Multimodal Neuromonitoring in Critically Ill Mechanically Ventilated COVID-19 Patients | Battaglini, D. Santori, G. Chandraptham, K. Iannuzzi, F. Bastianello, M. Tarantino, F. Ball, L. Giacobbe, D. R. Vena, A. Bassetti, M. Inglese, M. Uccelli, A. Rocco, P. R. M. Patroniti, N. Brunetti, I. Pelosi, P. Robba, C. | Front Neurol | 2020 |
Covid-19 |
| Association between plasma tau and postoperative delirium incidence and severity: a prospective observational study | Ballweg, T. White, M. Parker, M. Casey, C. Bo, A. Farahbakhsh, Z. Kayser, A. Blair, A. Lindroth, H. Pearce, R. A. Blennow, K. Zetterberg, H. Lennertz, R. Sanders, R. D. | Br J Anaesth | 2020 |
biomarker |
| Neurocovid: Pharmacological Recommendations for Delirium Associated With COVID-19 | Baller, E. B. Hogan, C. S. Fusunyan, M. A. Ivkovic, A. Luccarelli, J. W. Madva, E. Nisavic, M. Praschan, N. Quijije, N. V. Beach, S. R. Smith, F. A. | Psychosomatics | 2020 |
Adrenergic alpha-2 Receptor Agonists/ therapeutic use |
| An Implementation Assessment of the Virtual Acute Care for Elders Program From the Perspective of Key Stakeholders | Balentine, C. J. Morris, M. Knight, S. J. Turan, J. M. Flood, K. L. Gutierrez-Meza, D. Macdonald, C. L. Bhatia, S. Brown, C. J. | Ann Surg | 2020 | |
| The 'third wave': impending cognitive and functional decline in COVID-19 survivors | Baker, H. A. Safavynia, S. A. Evered, L. A. | Br J Anaesth | 2020 |
Covid-19 |
| Presence of urinary symptoms in bacteremic urinary tract infection: a retrospective cohort study of Escherichia coli bacteremia | Bai, A. D. Bonares, M. J. Thrall, S. Bell, C. M. Morris, A. M. | BMC Infect Dis | 2020 |
Aged |
| Risk Factors of Postoperative Delirium in Older Adult Spine Surgery Patients: A Meta-Analysis | Baek, W. Kim, Y. M. Lee, H. | AORN J | 2020 |
delirium |
| Psychosocial volunteer support for older adults with cognitive impairment: development of MyCare Ageing using a codesign approach via action research | Ayton, D. O'Donnell, R. Vicary, D. Bateman, C. Moran, C. Srikanth, V. K. Lustig, J. Banaszak-Holl, J. Hunter, P. Pritchard, E. Morris, H. Savaglio, M. Parikh, S. Skouteris, H. | BMJ Open | 2020 |
dementia |
| The Volunteer Dementia and Delirium Care (VDDC)©: A pre-implementation study exploring perceived acceptability to implementing the program in an acute and subacute metropolitan hospital | Ayton, D. Moran, C. Berkovic, D. Bateman, C. Anderson, K. Blair, A. Soh, S. E. Morello, R. Lim, Y. Y. Liew, D. | Australas J Ageing | 2020 |
delirium |
| A call to action for delirium research: Meta-analysis and regression of delirium associated mortality | Aung Thein, M. Z. Pereira, J. V. Nitchingham, A. Caplan, G. A. | BMC Geriatr | 2020 |
Aged |
| Accuracy and Feasibility of Clinically Applied Frailty Instruments before Surgery: A Systematic Review and Meta-analysis | Aucoin, S. D. Hao, M. Sohi, R. Shaw, J. Bentov, I. Walker, D. McIsaac, D. I. | Anesthesiology | 2020 |
Aged |
| Could COVID delirium bring on dementia? | Arnold, C. | Nature | 2020 |
COVID-19/ complications/epidemiology/ psychology |
| Neighborhood-Level Social Disadvantage and Risk of Delirium Following Major Surgery | Arias, F. Chen, F. Fong, T. G. Shiff, H. Alegria, M. Marcantonio, E. R. Gou, Y. Jones, R. N. Travison, T. G. Schmitt, E. M. Kind, A. J. H. Inouye, S. K. | J Am Geriatr Soc | 2020 |
Area Deprivation Index |
| Delirium is independently associated with early mortality in elderly patients starting hemodialysis | Arai, Y. Shioji, S. Tanaka, H. Kondo, I. Sakamoto, E. Suzuki, M. Katagiri, D. Tada, M. Hinoshita, F. | Clin Exp Nephrol | 2020 |
Chronic kidney disease |
| COVID-19 inpatients with psychiatric disorders: Real-world clinical recommendations from an expert team in consultation-liaison psychiatry | Anmella, G. Arbelo, N. Fico, G. Murru, A. Llach, C. D. Madero, S. Gomes-da-Costa, S. Imaz, M. L. López-Pelayo, H. Vieta, E. Pintor, L. | J Affect Disord | 2020 |
Aged |
| Relationship Between Intensive Care Unit Delirium Severity and 2-Year Mortality and Health Care Utilization | Andrews, P. S. Wang, S. Perkins, A. J. Gao, S. Khan, S. Lindroth, H. Boustani, M. Khan, B. | American journal of critical care : an official publication, American Association of Critical-Care Nurses | 2020 |
adult |
| Impact of a Pharmacist-Led Intensive Care Unit Sleep Improvement Protocol on Sleep Duration and Quality | Andrews, J. L. Louzon, P. R. Torres, X. Pyles, E. Ali, M. H. Du, Y. Devlin, J. W. | Ann Pharmacother | 2020 |
activity tracker |
| A Case of Concurrent Delirium and Catatonia in a Woman With Coronavirus Disease 2019 | Amouri, J. Andrews, P. S. Heckers, S. Ely, E. W. Wilson, J. E. | Psychosomatics | 2020 | |
| Delirium pathway: a North Hampshire experience | Al-Rawi, Y. A. | Progress in Neurology and Psychiatry | 2020 |
aged |
| Incidence and risk factors for acute delirium in older patients with a hip fracture: A retrospective cohort study | Aldwikat, R. K. Manias, E. Nicholson, P. | Nurs Health Sci | 2020 |
hip fracture |
| Delirium, insulin-like growth factor I, growth hormone in older inpatients | Adamis, D. Coada, I. Eikelenboom, P. Chu, C. S. Finn, K. Melvin, V. Williams, J. Meagher, D. J. McCarthy, G. | World J Psychiatry | 2020 |
Cognition |
| Critical Review and Meta-Analysis of Postoperative Sedation after Adult Cardiac Surgery: Dexmedetomidine Versus Propofol | Abowali, H. A. Paganini, M. Enten, G. Elbadawi, A. Camporesi, E. M. | J Cardiothorac Vasc Anesth | 2020 |
adult open cardiac surgery |
| Polypharmacy at admission prolongs length of hospitalization in gastrointestinal surgery patients | Abe, N. Kakamu, T. Kumagai, T. Hidaka, T. Masuishi, Y. Endo, S. Kasuga, H. Fukushima, T. | Geriatr Gerontol Int | 2020 |
Adult |
| Stroke-related delirium | Al-Khaled, M. | Journal of the Neurological Sciences | 2021 |
article |
| Practice Variability in Screening and Treating Pediatric Critical Illness Delirium: Survey | Aljabari, S. Carter, C. Waheed, S. Anderson, J. E. | Journal of Pediatric Intensive Care | 2020 |
child |
| Perioperative complications of pediatric otorhinolaryngological operations | Aleksandrovich, Y. Rybianov, V. Pshenisnov, K. V. Razumov, S. | Saudi Journal of Anaesthesia | 2020 |
Complications ENT Heart rate variability Pediatric Perioperative |
| Prevention as Intervention: Reducing Incident Delirium in Heart Failure | Albert, B. L. | Journal of doctoral nursing practice | 2019 |
acute heart failure |
| The prevalence of prescribing medications associated with geriatric syndromes among discharged elderly patients | Akkawi, M. E. Taufek, N. H. M. Hadi, A. D. A. Nik Lah, N. N. N. F. | Journal of Pharmacy and Bioallied Sciences | 2020 |
Elderly patients Geriatric Syndromes Medication prescribing |
| Incidence and predictors of delirium after cardiac arrest – A retrospective registry | Aicher, N. Jäckel, M. Faye, C. Wengenmayer, T. Bode, C. Staudacher, D. L. | Resuscitation | 2020 |
noradrenalin |
| Is ketamine safe for the pre-hospital sedation of patients with excited delirium secondary to sympathomimetic toxicity? | Adams, Y. | Australasian Journal of Paramedicine | 2019 |
adrenergic receptor stimulating agent |
| Prospective, multi-centric benchmark study assessing delirium: prevalence, incidence and its correlates in hospitalized elderly Lebanese patients | Zrour, C. Haddad, R. Zoghbi, M. Kharsa, Z. Hijazi, M. Naja, W. | Aging Clin Exp Res | 2020 |
Correlated factors |
| Knowledge and attitudes of adolescents with psychiatric disorders and their caregivers towards electroconvulsive therapy in China | Zong, Q. Q. Qi, H. Wang, Y. Y. Zhang, C. Balbuena, L. Ungvari, G. S. An, F. R. Xiang, Y. T. | Asian Journal of Psychiatry | 2020 |
adolescent |
| Does postoperative delirium following elective noncardiac surgery predict long-term mortality? | Ziman, N. Sands, L. P. Tang, C. Zhu, J. Leung, J. M. | Age Ageing | 2020 |
long-term mortality |
| Anxiety administrated by dexmedetomidine to prevent new-onset of postoperative atrial fibrillation in patients undergoing off-pump coronary artery bypass graft | Zi, J. Fan, Y. Dong, C. Zhao, Y. Li, D. Tan, Q. | International Heart Journal | 2020 |
1800014314 |
| Assessment of Melatonergics in Prevention of Delirium: A Systematic Review and Meta-Analysis | Zhu, Y. Jiang, Z. Huang, H. Li, W. Ren, C. Yao, R. Wang, Y. Yao, Y. Li, W. Du, B. Xi, X. | Front Neurol | 2020 |
critical care medicine |
| Geriatric Nutritional Risk Index can predict postoperative delirium and hospital length of stay in elderly patients undergoing non-cardiac surgery | Zhao, Y. Xia, X. Xie, D. Liao, Y. Wang, Y. Chen, L. Ge, N. Yue, J. | Geriatr Gerontol Int | 2020 |
Geriatric Nutritional Risk Index |
| The geriatric nutrition risk index versus the mini-nutritional assessment short form in predicting postoperative delirium and hospital length of stay among older non-cardiac surgical patients: a prospective cohort study | Zhao, Y. Ge, N. Xie, D. Gao, L. Wang, Y. Liao, Y. Yue, J. | BMC Geriatr | 2020 |
Geriatric nutritional risk index |
| Perioperative Multicomponent Interdisciplinary Program Reduces Delirium Incidence in Elderly Patients With Hip Fracture | Zhao, X. Yuan, W. | J Am Psychiatr Nurses Assoc | 2020 |
delirium |
| Emergence delirium is associated with increased postoperative delirium in elderly: a prospective observational study | Zhang, Y. He, S. T. Nie, B. Li, X. Y. Wang, D. X. | J Anesth | 2020 |
Elderly |
| S100β as a potential biomarker of incident delirium: a systematic review and meta-analysis | Zhang, X. Lyu, Y. Wang, D. | Minerva Anestesiol | 2020 | |
| Effects of Dexmedetomidine on Postoperative Delirium and Expression of IL-1β, IL-6, and TNF-α in Elderly Patients After Hip Fracture Operation | Zhang, W. Wang, T. Wang, G. Yang, M. Zhou, Y. Yuan, Y. | Front Pharmacol | 2020 |
dexmedetomidine |
| Nomogram Model for Predicting Risk of Postoperative Delirium After Deep Brain Stimulation Surgery in Patients Older Than 50 Years with Parkinson Disease | Zhan, L. Wang, X. Q. Zhang, L. X. | World Neurosurg | 2020 |
Advanced age |
| Combining Ultrafast Anaesthesia and Minimal Invasive Implantation in HeartMate 3: A Pilot Study | Zayat, R. Ahmad, U. Twarie, L. Moza, A. Schaelte, G. Allham, O. Haneya, A. Khattab, M. Schnoering, H. Autschbach, R. | The Journal of heart and lung transplantation | 2020 |
adult |
| Exosome α-Synuclein Release in Plasma May be Associated With Postoperative Delirium in Hip Fracture Patients | Yuan, Y. Li, Z. Yang, N. Han, Y. Ji, X. Han, D. Wang, X. Li, Y. Liu, T. Yuan, F. He, J. Liu, Y. Ni, C. Zou, P. Wang, G. Guo, X. Zhou, Y. | Front Aging Neurosci | 2020 |
exosome |
| A multicentre, pragmatic, cluster randomised, controlled feasibility trial of the POD system of care | Young, J. Green, J. Farrin, A. Collinson, M. Hartley, S. Smith, J. Teale, E. Siddiqi, N. Inouye, S. K. | Age Ageing | 2020 |
delirium |
| Association of Reversal of Anticoagulation Preoperatively on 30-Day Mortality and Outcomes for Hip Fracture Surgery | Yoo, M. S. Zhu, S. Jiang, S. F. Hammer, H. L. McBride, W. J. McCarthy, C. M. Green, C. E. Ananias, M. P. | American Journal of Medicine | 2020 |
adult |
| Perioperative Complications and Prognosis of Curative Surgical Resection for Spinal Metastases in Elderly Patients | Yonezawa, N. Murakami, H. Demura, S. Kato, S. Yoshioka, K. Shinmura, K. Yokogawa, N. Shimizu, T. Oku, N. Kitagawa, R. Handa, M. Annen, R. Kurokawa, Y. Tsuchiya, H. | World Neurosurgery | 2020 |
titanium cage |
| Risk factors for delirium in intensive care unit and its duration | Yanyan, L. Dajiang, Y. Xiaoya, L. Shao, W. | Zhonghua Wei Zhong Bing Ji Jiu Yi Xue | 2020 |
sedative agent |
| Melatonergic agents in the prevention of delirium: A network meta-analysis of randomized controlled trials | Yang, C. P. Tseng, P. T. Pei-Chen Chang, J. Su, H. Satyanarayanan, S. K. Su, K. P. | Sleep Med Rev | 2020 |
Delirium |
| Oxycodone preemptive analgesia after endoscopic plasma total adenotonsillectomy in children a randomized controlled trial | Wu, J. Gui, Q. Wang, J. Ye, J. Xia, Z. Wang, S. Liu, F. Kong, F. Zhong, L. | Medicine (United States) | 2020 |
ChiCTR-INR-16009116 |
| Delirium screening practice in specialist palliative care units: a survey | Woodhouse, R. Siddiqi, N. Boland, J. W. Featherstone, I. Johnson, M. J. | BMJ Support Palliat Care | 2020 |
delirium |
| Movements and trends in intensive care pain treatment and sedation: What matters to the patient? | Wøien, H. | J Clin Nurs | 2020 |
Adult |
| Quetiapine therapy in critically injured trauma patients is associated with an increased risk of pulmonary complications | Wessels, L. E. Wallace, J. D. Calvo, R. Y. Levko, T. Bowie, J. M. Butler, W. J. Bansal, V. Sise, C. B. Martin, M. J. Sise, M. J. | Am J Surg | 2020 |
Antipsychotic Agents/ adverse effects |
| Combined non-intubated anaesthesia and paravertebral nerve block in comparison with intubated anaesthesia in children undergoing video-assisted thoracic surgery | Wei, W. Fan, Y. Liu, W. Zhao, T. Tian, H. Xu, Y. Tan, Y. Song, X. Ma, D. | Acta Anaesthesiol Scand | 2020 | |
| The occurrence and timing of delirium in acute care hospitalizations in the last year of life: A population-based retrospective cohort study | Webber, C. Watt, C. L. Bush, S. H. Lawlor, P. G. Talarico, R. Tanuseputro, P. | Palliat Med | 2020 |
Delirium |
| Frailty screening in hospitalised older adults: How does the brief Dutch National Safety Management Program perform compared to a more extensive approach? | Warnier, R. M. J. van Rossum, E. van Kuijk, S. M. J. Magdelijns, F. Schols, Jmga Kempen, Gijm | J Clin Nurs | 2020 |
Aged |
| Predicting postoperative delirium after microvascular decompression surgery with machine learning | Wang, Y. Lei, L. Ji, M. Tong, J. Zhou, C. M. Yang, J. J. | J Clin Anesth | 2020 |
Machine learning |
| Propensity score-adjusted three-component mixture model for drug-drug interaction data mining in FDA Adverse Event Reporting System | Wang, X. Li, L. Wang, L. Feng, W. Zhang, P. | Statistics in Medicine | 2020 |
amfebutamone |
| Comparison between Dexmedetomidine and Midazolam for Sedation in Patients with Intubation after Oral and Maxillofacial Surgery | Wang, L. Zhang, T. Huang, L. Peng, W. | Biomed Res Int | 2020 | |
| Comparison of Intranasal Dexmedetomidine and Oral Midazolam for Premedication in Pediatric Dental Patients under General Anesthesia: A Randomised Clinical Trial | Wang, L. Huang, L. Zhang, T. Peng, W. | Biomed Res Int | 2020 | |
| Accelerated magnetic seizure therapy (aMST) for treatment of major depressive disorder: A pilot study | Wang, J. Vila-Rodriguez, F. Ge, R. Gao, S. Gregory, E. Jiang, W. Yang, C. Wang, G. | J Affect Disord | 2020 |
Cognition |
| Development and validation of the delirium risk assessment score (DRAS) | Vreeswijk, R. Kalisvaart, I. Maier, A. B. Kalisvaart, K. J. | Eur Geriatr Med | 2020 |
Delirium |
| Development and validation of the delirium risk assessment score (DRAS) | Vreeswijk, R. Kalisvaart, I. Maier, A. B. Kalisvaart, K. J. | Eur Geriatr Med | 2020 |
Delirium |
| Hospital readmission following transjugular intrahepatic portosystemic shunt: A 14-year single-center experience | Vozzo, C. F. Singh, T. Bullen, J. Sarvepalli, S. McCullough, A. Kapoor, B. | Gastroenterology Report | 2020 |
politef implant |
| Anticholinergic drug exposure at intensive care unit admission affects the occurrence of delirium. A prospective cohort study | Vondeling, A. M. Knol, W. Egberts, T. C. G. Slooter, A. J. C. | Eur J Intern Med | 2020 |
Anticholinergics |
| Delirium Screening in Neurocritical Care and Stroke Unit Patients: A Pilot Study on the Influence of Neurological Deficits on CAM-ICU and ICDSC Outcome | von Hofen-Hohloch, J. Awissus, C. Fischer, M. M. Michalski, D. Rumpf, J. J. Classen, J. | Neurocrit Care | 2020 |
Cam-icu |
| Intensive Care Unit Delirium in Surgical Patients Is Associated with Upregulation in Tryptophan Metabolism | Voils, S. A. Shoulders, B. R. Singh, S. Solberg, L. M. Garrett, T. J. Frye, R. F. | Pharmacotherapy | 2020 |
critical care |
| Vitamin D and Postoperative Delirium After Coronary Artery Bypass Grafting: A Prospective Cohort Study | Velayati, A. Vahdat Shariatpanahi, M. Dehghan, S. Zayeri, F. Vahdat Shariatpanahi, Z. | Journal of Cardiothoracic and Vascular Anesthesia | 2020 |
adult |