Delirium Bibliography

Delirium Bibliography books graphicWhat is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!

How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.

Reference Information

Title
Preoperative medication use and postoperative delirium: a systematic review.
Authors
Kassie, G. M. Nguyen, T. A. Kalisch Ellett, L. M. Pratt, N. L. Roughead, E. E.
Year
2017
Journal
BMC Geriatr
Abstract

BACKGROUND: Medications are frequently reported as both predisposing factors and inducers of delirium. This review evaluated the available evidence and determined the magnitude of risk of postoperative delirium associated with preoperative medication use. METHODS: A systematic search in Medline and EMBASE was conducted using MeSH terms and keywords for postoperative delirium and medication. Studies which included patients 18 years and older who underwent major surgery were included. The methodological quality of included studies was assessed independently by two authors using the Newcastle-Ottawa quality assessment scale for cohort studies. RESULTS: Twenty-nine studies; 25 prospective cohort, three retrospective cohort and one post hoc analysis of RCT data were included. Only four specifically aimed to assess medicines as an independent predictor of delirium, all other studies included medicines among a number of potential predictors of delirium. Of the studies specifically testing the association with a medication class, preoperative use of beta-blockers (OR = 2.06[1.18-3.60]) in vascular surgery and benzodiazepines RR 2.10 (1.23-3.59) prior to orthopedic surgery were significant. However, evidence is from single studies only. Where medicines were included as one possible factor among many, hypnotics had a similar risk estimate to the benzodiazepine study, with one significant and one non-significant result. Nifedipine use prior to cardiac surgery was found to be significantly associated with delirium. The non-specific grouping of psychoactive medication use preoperatively was generally higher with an associated two-to-seven-fold higher risk of postoperative delirium, while only two studies included narcotics without other agents, with one significant and one non-significant result. CONCLUSIONS: There was a limited number of high quality studies in the literature quantifying the direct association between preoperative medication use and postsurgical delirium. More studies are required to evaluate the association of specific preoperative medications on the risk of postoperative delirium so that comprehensive guidelines for medicine use prior to surgery can be developed to aid delirium prevention. TRIAL REGISTRATION: This systematic review has been registered on PROSPERO International prospective register of systematic reviews (Registration number: CRD42016051245 ).

PMID

29284416

Keywords

Adverse drug event
Delirium
Elderly
Medication
Medication related problem
Medication safety
Prevention
Risk factor

Page(s)
298
Issue
1

Search:
Total Records Found: 6080, showing 100 per page
TitleAuthorsJournalYearKeywords
Activity-based occupational therapy intervention for delirium superimposed on dementia in nursing home setting: a feasibility study Pozzi, C. Lanzoni, A. Lucchi, E. Salimbeni, I. DeVreese, L. P. Bellelli, G. Fabbo, A. Morandi, A. Aging Clin Exp Res 2019

Delirium
Dementia
Nursing home
Occupational therapy
Tailor-made activity

Trials Focusing on Prevention and Treatment of Delirium After Cardiac Surgery: A systematic Review of Randomized Evidence Pieri, M. De Simone, A. Rose, S. De Domenico, P. Lembo, R. Denaro, G. Landoni, G. Monaco, F. Journal of Cardiothoracic and Vascular Anesthesia 2019

adult
anesthesia
cardiopulmonary bypass
controlled study
double blind procedure
Europe
female
heart surgery
human
intensive care
ischemic preconditioning
male
Medline
North America
operating room
postoperative delirium
prevention
randomized controlled trial (topic)
review
Scopus
surgery
systematic review
dexmedetomidine
glucocorticoid
inhalation anesthetic agent
ketamine
local anesthetic agent
neuroleptic agent
opiate
propofol

Association of comt val158met polymorphism with delirium risk and outcomes after traumatic brain injury Nekrosius, D. Kaminskaite, M. Jokubka, R. Pranckeviciene, A. Lideikis, K. Tamasauskas, A. Bunevicius, A. Journal of Neuropsychiatry and Clinical Neurosciences 2019

methionine
valine
adult
age
alcohol abuse
allele
article
cognition
cohort analysis
COMT gene
delirium
female
functional status
gene
genetic association
genotype
Glasgow coma scale
Glasgow Outcome on Discharge Scale
human
injury severity
major clinical study
male
Montreal cognitive assessment
observational study
patient monitoring
patient risk
priority journal
prospective study
rating scale
risk factor
single nucleotide polymorphism
traumatic brain injury

Anticholinergic burden of long-term medication is an independent risk factor for the development of postoperative delirium: A clinical trial Mueller, A. Spies, C. D. Eckardt, R. Weiss, B. Pohrt, A. Wernecke, K. D. Schmidt, M. Journal of Clinical Anesthesia 2019

aged
article
cancer patient
cancer surgery
complication
controlled study
ethics
female
female genital tract cancer
Germany
human
intervention study
major clinical study
male
non invasive procedure
outcome assessment
polypharmacy
postoperative delirium
preoperative evaluation
randomized controlled trial
risk assessment
risk factor
university hospital
cholinergic receptor blocking agent

Renal function and delirium in older fracture patients: different information from different formulas? Mossello, E. Rivasi, G. Tortu, V. Giordano, A. Iacomelli, I. Cavallini, M. C. Rafanelli, M. Ceccofiglio, A. Cartei, A. Rostagno, C. Bari, M. D. Ungar, A. Eur J Intern Med 2019

Creatinine
Cystatin C
Delirium
Glomerular filtration rate

Reversibility of delirium in Ill-hospitalized cancer patients: Does underlying etiology matter? Matsuda, Y. Maeda, I. Morita, T. Yamauchi, T. Sakashita, A. Watanabe, H. Kaneishi, K. Amano, K. Iwase, S. Ogawa, A. Yoshiuchi, K. Cancer Med 2019

cancer
cause
delirium
palliative care
reversibility

Association Between Perioperative Hypotension and Delirium in Postoperative Critically Ill Patients: A Retrospective Cohort Analysis Maheshwari, K. Ahuja, S. Khanna, A. K. Mao, G. Perez-Protto, S. Farag, E. Turan, A. Kurz, A. Sessler, D. I. Anesth Analg 2019
A short delirium caregiver questionnaire for triage of elderly outpatients with cognitive impairment: a development and test accuracy study Luijendijk, H. J. Quispel-Aggenbach, D. W. P. Stroomer-van Wijk, A. J. M. Meijerink-Blom, A. H. van Walbeek, A. Zuidema, S. U. International Psychogeriatrics 2019

aged
article
caregiver
cognitive defect
controlled study
diagnostic test accuracy study
disease course
emergency health service
female
gerontopsychiatry
hallucination
human
major clinical study
male
outcome assessment
outpatient
patient referral
questionnaire
sensitivity and specificity
sleep
telephone

Intraoperative Oxidative Damage and Delirium after Cardiac Surgery Lopez, M. G. Hughes, C. G. DeMatteo, A. O'Neal, J. B. McNeil, J. B. Shotwell, M. S. Morse, J. Petracek, M. R. Shah, A. S. Brown, N. J. Billings, F. T. th Anesthesiology 2019
Postoperative delirium after hip surgery is a potential risk factor for incident dementia: A systematic review and meta-analysis of prospective studies Lee, S. J. Jung, S. H. Lee, S. U. Lim, J. Y. Yoon, K. S. Lee, S. Y. Arch Gerontol Geriatr 2019

Delirium
Dementia
Hip fractures
Hip replacement
Meta-analysis

Evaluation of emergency department derived delirium prediction models using a hospital-wide cohort Lee, S. Harland, K. Mohr, N. M. Matthews, G. Hess, E. P. Bellolio, M. F. Han, J. H. Weckmann, M. Carnahan, R. Journal of Psychosomatic Research 2019

aged
article
cohort analysis
controlled study
delirium
delirium observation screening scale
diagnostic test accuracy study
emergency ward
female
hospitalization
human
ICD-10
ICD-9
major clinical study
male
model
nurse
observational study
predictive value
psychological rating scale
retrospective study
risk assessment
sensitivity and specificity
university hospital
very elderly

The Practical Use of White Cell Inflammatory Biomarkers in Prediction of Postoperative Delirium after Cardiac Surgery Kotfis, K. Slozowska, J. Safranow, K. Szylinska, A. Listewnik, M. Brain Sci 2019

Nlr
Plr
Pod
Pwr
biomarkers
cardiac surgery
delirium
prediction index

Characteristics, risk factors and outcome of early-onset delirium in elderly patients with first ever acute ischemic stroke-A prospective observational cohort study Kotfis, K. Bott-Olejnik, M. Szylińska, A. Listewnik, M. Rotter, I. Clinical Interventions in Aging 2019

NCT03944694
C reactive protein
troponin T
aged
article
atrial fibrillation
blood cell ratio
brain ischemia
clinical feature
cohort analysis
controlled study
delirium
disease association
female
hemianopia
hospital admission
human
incidence
major clinical study
male
mortality
neutrophil lymphocyte ratio
observational study
outcome assessment
platelet white blood cell count ratio
retrospective study
risk factor

Biomarkers of Delirium Duration and Delirium Severity in the ICU Khan, B. A. Perkins, A. J. Prasad, N. K. Shekhar, A. Campbell, N. L. Gao, S. Wang, S. Khan, S. H. Marcantonio, E. R. Twigg, H. L., 3rd Boustani, M. A. Crit Care Med 2019
The Role of Inflammation after Surgery for Elders (RISE) study: Study design, procedures, and cohort profile Hshieh, T. T. Vasunilashorn, S. M. D'Aquila, M. L. Arnold, S. E. Dickerson, B. C. Fong, T. G. Jones, R. N. Marcantonio, E. R. Schmitt, E. M. Xu, G. Gou, Y. Chen, F. Kunze, L. J. Vlassakov, K. V. Abdeen, A. R. Lange, J. K. Earp, B. E. Touroutoglou, A. Carl Alzheimers Dement 2019

Biomarkers
Cerebrospinal fluid
Delirium
Inflammation
Methods
Plasma
Positron emission tomography
Surgery

Clock Drawing Performance Slows for Older Adults after Total Knee Replacement Surgery Hizel, L. P. Warner, E. D. Wiggins, M. E. Tanner, J. J. Parvataneni, H. Davis, R. Penney, D. L. Libon, D. J. Tighe, P. Garvan, C. W. Price, C. C. Anesthesia and Analgesia 2019

nct01786577
aged
article
clock drawing test
cognition
controlled clinical trial
controlled study
delirium
female
human
latent period
major clinical study
male
observational study
priority journal
prospective study
total knee arthroplasty

Postoperative delirium after lung resection for primary lung cancer: Risk factors, risk scoring system, and prognosis Hayashi, K. Motoishi, M. Sawai, S. Horimoto, K. Hanaoka, J. PLoS One 2019
Intraoperative Low Alpha Power in the Electroencephalogram Is Associated With Postoperative Subsyndromal Delirium Gutierrez, R. Egaña, J. I. Saez, I. Reyes, F. Briceño, C. Venegas, M. Lavado, I. Penna, A. Frontiers in Systems Neuroscience 2019

electroencephalograph
age
aged
alpha rhythm
anesthesia
article
assessment of humans
clinical article
cohort analysis
Confusion Assessment Method
controlled study
delirium
delta rhythm
electroencephalography
female
human
intraoperative period
male
minimum lung alveolus concentration
Montreal cognitive assessment
observational study
postoperative delirium
power spectrum
receiver operating characteristic
sensitivity and specificity
subsyndromal delirium

Post-operative delirium associated with metabolic alterations following hemi-arthroplasty in older patients Guo, Y. Li, Y. Zhang, Y. Fang, S. Xu, X. Zhao, A. Zhang, J. Li, J. V. Ma, D. Jia, W. Jiang, W. Age Ageing 2019

hip fracture
metabolomics
older patients
post-operative delirium

Validation of the Delirium Diagnostic Tool-Provisional (DDT-Pro) With Medical Inpatients and Comparison With the Confusion Assessment Method Algorithm Franco, J. G. Ocampo, M. V. Velásquez-Tirado, J. D. Zaraza, D. R. Giraldo, A. M. Serna, P. A. López, C. Zuluaga, A. Sepúlveda, E. Kean, J. Trzepacz, P. T. Journal of Neuropsychiatry and Clinical Neurosciences 2019

administrative personnel
adult
algorithm
article
consultation
content validity
controlled study
delirium
dementia
diagnosis
diagnostic accuracy
diagnostic test accuracy study
disease course
DSM-5
female
hospital patient
human
internal consistency
interrater reliability
major clinical study
male
neuropsychiatry
nurse
nursing assessment
physician
psychological rating scale
receiver operating characteristic
sensitivity and specificity
standard
traumatic brain injury

Efficacy and safety of haloperidol for delirium prevention in adult patients: An updated meta-analysis with trial sequential analysis of randomized controlled trials Chen, Z. Chen, R. Zheng, D. Su, Y. Wen, S. Guo, H. Ye, Z. Deng, Y. Liu, G. Zuo, L. Wei, X. Hou, Y. Journal of Clinical Anesthesia 2019

adult
artificial ventilation
Cochrane Library
controlled study
delirium
drug safety
drug therapy
Embase
extrapyramidal symptom
female
hospitalization
human
incidence
intensive care unit
male
Medline
meta analysis
mortality
outcome assessment
pharmacokinetics
prevention
prophylaxis
QT prolongation
quality control
randomized controlled trial (topic)
review
risk factor
sequential analysis
systematic review
Web of Science
haloperidol
placebo
sodium chloride

Change in Serum Level of Interleukin 6 and Delirium After Coronary Artery Bypass Graft Chen, Y. Lu, S. Wu, Y. Shen, Y. Zhao, H. Ding, S. Feng, X. Sun, L. Tao, X. Li, J. Ma, R. Liu, W. Wu, F. Feng, Y. Am J Crit Care 2019
Preoperative cardiac function parameters as valuable predictors for nurses to recognise delirium after cardiac surgery: a prospective cohort study Cai, S. Latour, J. M. Lin, Y. Pan, W. Zheng, J. Xue, Y. Gao, J. Lv, M. Zhang, X. Luo, Z. Wang, C. Zhang, Y. Eur J Cardiovasc Nurs 2019

Cardiac surgery
cardiac function
delirium
intensive care units
predictors

Bedside mental status and outcome in elderly patients admitted for acute coronary syndromes Briet, C. Blanchart, K. Lemaitre, A. Roux, I. Lavergne, K. Rocamora, A. Bignon, M. Ardouin, P. Sabatier, R. Roule, V. Beygui, F. Heart 2019

acute coronary syndrome
cognitive impairment
death
delirium
elderly
outcome
grants from Biosensors, Medtronic and Boston Scientific.

Delirium Screening in Aphasic Patients With the Intensive Care Delirium Screening Checklist (ICDSC): A Prospective Cohort Study Bosselmann, C. Zurloh, J. Stefanou, M. I. Stadler, V. Weber, Y. Lerche, H. Poli, S. Ziemann, U. Mengel, A. Front Neurol 2019

intensive care delirium screening checklist
intracerebral hemorrhage
post-stroke aphasia
post-stroke delirium
stroke

Impact of Frailty on 30-Day Morbidity and Mortality of Patients With Intertrochanteric Femur Fractures Boissonneault, A. Mener, A. Schwartz, A. Wilson, J. Staley, C. Schenker, M. Orthopedics 2019
The utility of nursing instruments for daily screening for delirium: Delirium causes substantial functional impairment Bode, L. Isler, F. Fuchs, S. Marquetand, J. Petry, H. Ernst, J. Schubert, M. Garcia Nunez, D. von Kanel, R. Boettger, S. Palliat Support Care 2019

Assessment
Delirium
Electronic Patient Assessment-Acute Care (ePA-AC)
Functional impairment
Nursing

The short IQCODE as a predictor for delirium in hospitalized geriatric patients Blandfort, S. Gregersen, M. Rahbek, K. Juul, S. Damsgaard, E. M. Aging Clin Exp Res 2019

Delirium predictor
Geriatrics
Iqcode
Older patient

The relationship among frailty, delirium and attentional tests to detect delirium: a cohort study Bellelli, P. G. Biotto, M. Morandi, A. Meagher, D. Cesari, M. Mazzola, P. Annoni, G. Zambon, A. Eur J Intern Med 2019

Attention
Delirium
Frailty
Geriatric
Older patients

Haloperidol for the treatment of delirium in critically ill patients: A systematic review with meta-analysis and Trial Sequential Analysis Barbateskovic, M. Krauss, S. R. Collet, M. O. Andersen-Ranberg, N. C. Mathiesen, O. Jakobsen, J. C. Perner, A. Wetterslev, J. Acta Anaesthesiologica Scandinavica 2019

adult
all cause mortality
cognition
controlled study
critically ill patient
delirium
drug therapy
extrapyramidal symptom
female
human
male
meta analysis
QT prolongation
quality of life
randomized controlled trial (topic)
review
sensitivity analysis
sequential analysis
systematic review
haloperidol

The Volunteer Dementia and Delirium Care (VDDC) © Program: An Exploration of Perceived Barriers and Enablers to Implementation in an Acute and Subacute Metropolitan Hospital Ayton, D. Moran, C. Berkovic, D. Bateman, C. Anderson, K. Blair, A. Soh, S. E. Morello, R. Ying Lim, Y. Liew, D. Australas J Ageing 2019

delirium
dementia
hospital
volunteers

Comorbidities rather than age affect medium-term outcome in octogenarian patients after total knee arthroplasty Andreozzi, V. Conteduca, F. Iorio, R. Di Stasio, E. Mazza, D. Drogo, P. Annibaldi, A. Ferretti, A. Knee Surg Sports Traumatol Arthrosc 2019

Comorbidity
Complication
Elderly
Octogenarian
Total knee arthroplasty
Total knee replacement

Effect of the Tailored, Family-Involved Hospital Elder Life Program on Postoperative Delirium and Function in Older Adults: A Randomized Clinical Trial Wang, Y. Y. Yue, J. R. Xie, D. M. Carter, P. Li, Q. L. Gartaganis, S. L. Chen, J. Inouye, S. K. JAMA Intern Med 2019
Nomogram for Predicting Postoperative Delirium After Deep Brain Stimulation Surgery for Parkinson's Disease Wang, X. Q. Zhuang, H. X. Zhang, L. X. Chen, X. Niu, C. S. Zhao, M. World Neurosurg 2019

Deep brain stimulation
Nomograms
Parkinson’s disease
Postoperative delirium

Automated tracking of level of consciousness and delirium in critical illness using deep learning Sun, H. Kimchi, E. Akeju, O. Nagaraj, S. B. McClain, L. M. Zhou, D. W. Boyle, E. Zheng, W. L. Ge, W. Westover, M. B. NPJ Digital Medicine 2019

propofol
adult
aged
APACHE
article
artificial ventilation
body mass
brain function
clinical research
consciousness level
convolutional neural network
critical illness
deep learning
delirium
elective surgery
electroencephalography
eye movement
female
human
intensive care unit
long short term memory network
major clinical study
male
neuromonitoring
observational study
priority journal
prospective study
recurrent neural network
Richmond Agitation Sedation Scale
sedation
sensitivity and specificity

Impact of natural light exposure on delirium burden in adult patients receiving invasive mechanical ventilation in the ICU: a prospective study Smonig, R. Magalhaes, E. Bouadma, L. Andremont, O. de Montmollin, E. Essardy, F. Mourvillier, B. Lebut, J. Dupuis, C. Neuville, M. Lermuzeaux, M. Timsit, J. F. Sonneville, R. Ann Intensive Care 2019

Agitation
Antipsychotics
Delirium
Hallucinations
Light

Differences in 90-day mortality of delirium subtypes in the intensive care unit: A retrospective cohort study Rood, P. J. T. van de Schoor, F. van Tertholen, K. Pickkers, P. van den Boogaard, M. J Crit Care 2019

Critical care
Delirium
Icu
Mortality
Subtypes

The Role of Delirium and Other Risk Factors on Mortality in Elderly Patients with Critical Limb Ischemia Undergoing Major Lower Limb Amputation Roijers, J. P. Hopmans, C. J. Janssen, T. L. Mulder, P. G. H. Buimer, M. G. Ho, G. H. de Groot, H. G. W. Veen, E. J. van der Laan, L. Ann Vasc Surg 2019
Antipsychotics for preventing delirium in hospitalized adults a systematic review Oh, E. S. Needham, D. M. Nikooie, R. Wilson, L. M. Zhang, A. Robinson, K. A. Neufeld, K. J. Annals of Internal Medicine 2019

neuroleptic agent
adult
adverse event
cognition
delirium
delirium rating scale revised 98
Diagnostic and Statistical Manual of Mental Disorders
disease duration
drug safety
extrapyramidal symptom
heart arrhythmia
hospital patient
human
incidence
length of stay
mental disease assessment
meta analysis
mortality
neuroleptic malignant syndrome
priority journal
prophylaxis
review
sedation
systematic review

Antipsychotics for treating delirium in hospitalized adults a systematic review Nikooie, R. Neufeld, K. J. Oh, E. S. Wilson, L. M. Zhang, A. Robinson, K. A. Needham, D. M. Annals of Internal Medicine 2019

amisulpride
aripiprazole
haloperidol
neuroleptic agent
olanzapine
placebo
quetiapine
risperidone
ziprasidone
adult
Clinical Global Impression scale
critical illness
critically ill patient
delirium
drug withdrawal
extrapyramidal symptom
heart disease
hospital mortality
hospital patient
human
length of stay
meta analysis
neurologic disease
palliative therapy
priority journal
psychopharmacotherapy
QTc interval
randomized controlled trial (topic)
review
sedation
systematic review

Exploiting Machine Learning Algorithms and Methods for the Prediction of Agitated Delirium After Cardiac Surgery: Models Development and Validation Study Mufti, H. N. Hirsch, G. M. Abidi, S. R. Abidi, S. S. R. JMIR Med Inform 2019

cardiac surgery
delirium
machine learning
predictive modeling

Predictors and prognosis of delirium among older subjects in cardiac intensive care unit: focus on potentially preventable forms Mossello, E. Baroncini, C. Pecorella, L. Giulietti, C. Chiti, M. Caldi, F. Cavallini, M. C. Simoni, D. Baldasseroni, S. Fumagalli, S. Valoti, P. Stroppa, S. Parenti, K. Ungar, A. Masotti, G. Marchionni, N. Di Bari, M. Eur Heart J Acute Cardiovasc Care 2019

*Delirium
*acute coronary syndrome
*aged
*intensive care unit

Dysfunction of the blood-brain barrier in postoperative delirium patients, referring to the axonal damage biomarker phosphorylated neurofilament heavy subunit Mietani, K. Sumitani, M. Ogata, T. Shimojo, N. Inoue, R. Abe, H. Kawamura, G. Yamada, Y. PLoS One 2019
The 4 ‘a’s test for detecting delirium in acute medical patients: A diagnostic accuracy study Maclullich, A. M. J. Shenkin, S. D. Goodacre, S. Godfrey, M. Hanley, J. Stíobhairt, A. Lavender, E. Boyd, J. Stephen, J. Weir, C. Macraild, A. Steven, J. Black, P. Diernberger, K. Hall, P. Tieges, Z. Fox, C. Anand, A. Young, J. Siddiqi, N. Gray, A. Health Technology Assessment 2019

ISRCTN53388093
age
Arousal Attention Abbreviated Mental Test 4
article
awareness
biomedical technology assessment
clinical practice
community care
confidence interval
cost benefit analysis
cost effectiveness analysis
delirium
diagnostic accuracy
diagnostic test accuracy study
diagnostic value
documentation
emergency ward
England
false negative result
false positive result
frailty
health care policy
health economics
health status
hospital cost
hospitalization
human
information processing
interview
length of stay
long term care
medical education
mortality rate
national health organization
national health service
practice guideline
probability
psychologic assessment
qualitative research
receiver operating characteristic
scoring system
sensitivity and specificity
statistics
surgery
systematic review
United Kingdom
ward

Initiation and continuation of antipsychotic medicines in older people following non-psychiatric hospital admission Kalisch Ellett, L. M. Pratt, N. L. Apajee, J. Roughead, E. E. Int J Clin Pharm 2019

Antipsychotic
Australia
Delirium
Dementia
Elderly
Hospital admission

Staged Implementation of Awakening and Breathing, Coordination, Delirium Monitoring and Management, and Early Mobilization Bundle Improves Patient Outcomes and Reduces Hospital Costs Hsieh, S. J. Otusanya, O. Gershengorn, H. B. Hope, A. A. Dayton, C. Levi, D. Garcia, M. Prince, D. Mills, M. Fein, D. Colman, S. Gong, M. N. Critical Care Medicine 2019

adult
arousal
article
artificial ventilation
clinical practice
cohort analysis
controlled study
decubitus
delirium
female
hospital cost
human
length of stay
major clinical study
male
medical intensive care unit
mobilization
prospective study
ventilated patient

The Prevalence of Delirium in An Older Acute Surgical Population and Its Effect on Outcome Hewitt, J. Owen, S. Carter, B. R. Stechman, M. J. Tay, H. S. Greig, M. McCormack, C. Pearce, L. McCarthy, K. Myint, P. K. Moug, S. J. Geriatrics 2019

Cognitive impairment
delirium
older surgical patients

Care challenges in older general hospital patients : Impact of cognitive impairment and other patient-related factors Hendlmeier, I. Bickel, H. Hessler-Kaufmann, J. B. Schaufele, M. Z Gerontol Geriatr 2019

Adverse events
Cognitive impairment
Cross-sectional studies
Dementia
Nursing

Efficacy of music on sedation, analgesia and delirium in critically ill patients. A systematic review of randomized controlled trials Garcia Guerra, G. Almeida, L. Zorzela, L. King-Jones, S. Joffe, A. R. Hartling, L. Jou, H. Vohra, S. J Crit Care 2019

Analgesia
Delirium
Music
Sedation
Systematic review

Postoperative Pressure Ulcers After Geriatric Hip Fracture Surgery Are Predicted by Defined Preoperative Comorbidities and Postoperative Complications Galivanche, A. R. Kebaish, K. J. Adrados, M. Ottesen, T. D. Varthi, A. G. Rubin, L. E. Grauer, J. N. The Journal of the American Academy of Orthopaedic Surgeons 2019

adult
article
cohort analysis
comorbidity
complication
decubitus
female
hip fracture
human
insulin dependent diabetes mellitus
major clinical study
male
multicenter study
platelet count
pneumonia
postoperative delirium
preoperative evaluation
risk factor
sepsis
surgeon
surgery
total quality management
urinary tract infection

The Healthy Heart-Mind Trial: Randomized Controlled Trial of Melatonin for Prevention of Delirium Ford, A. H. Flicker, L. Kelly, R. Patel, H. Passage, J. Wibrow, B. Anstey, M. Edwards, M. Almeida, O. P. J Am Geriatr Soc 2019

cardiothoracic
delirium
melatonin
prevention
surgery

The Caregiver Burden of Delirium in Older Adults With Alzheimer Disease and Related Disorders Fong, T. G. Racine, A. M. Fick, D. M. Tabloski, P. Gou, Y. Schmitt, E. M. Hshieh, T. T. Metzger, E. Bertrand, S. E. Marcantonio, E. R. Jones, R. N. Inouye, S. K. J Am Geriatr Soc 2019

Alzheimer disease
Alzheimer disease or related disorder
caregiver burden
delirium burden
dementia
patient burden

Geriatric Events Among Older Adults Undergoing Nonelective Surgery Are Associated with Poor Outcomes Dworsky, J. Q. Childers, C. P. Copeland, T. Maggard-Gibbons, M. Tan, H. J. Saliba, D. Russell, M. M. Am Surg 2019
Shifting the focus: A QI project to improve the management of delirium in patients with hip fracture Dormandy, L. Mufti, S. Higgins, E. Bailey, C. Dixon, M. Future Healthc J 2019

Neck of femur fracture
delirium
perioperative medicine

Impact of a delirium prevention project among older hospitalized patients who underwent orthopedic surgery: a retrospective cohort study Choi, J. Y. Kim, K. I. Kang, M. G. Lee, Y. K. Koo, K. H. Oh, J. H. Park, Y. H. Suh, J. Kim, N. H. Yoo, H. J. Koo, J. Moon, H. M. Kim, E. H. Park, K. Kim, C. H. BMC Geriatr 2019

Delirium
Multidisciplinary geriatric intervention
Quality improvement project

Melatonin for the prevention of postoperative delirium in older adults: a systematic review and meta-analysis Campbell, A. M. Axon, D. R. Martin, J. R. Slack, M. K. Mollon, L. Lee, J. K. BMC Geriatr 2019

Delirium
Geriatric
Melatonin
Postoperative
Ramelteon

Assessment of a Geriatric Hip Fracture Program: Analysis of Harmful Adverse Events Using the Global Trigger Tool Blood, T. D. Deren, M. E. Goodman, A. D. Hayda, R. A. Trafton, P. G. Journal of Bone and Joint Surgery - American Volume 2019

acute blood loss anemia
age
aged
anemia
article
Charlson Comorbidity Index
clinical effectiveness
controlled study
death
disease severity
female
femoral neck fracture
femur intertrochanteric fracture
frequency
geriatric care
Geriatric Hip Fracture Program
Global Trigger Tool
health program
hip fracture
hospital admission
hospital patient
hospital readmission
human
length of stay
major clinical study
male
musculoskeletal disease assessment
postoperative delirium
predictor variable
priority journal
risk factor
trend study
urinary tract infection
very elderly

Clinical management of delirium: The response depends on the subtypes. An observational cohort study in 602 patients Zipser, C. M. Knoepfel, S. Hayoz, P. Schubert, M. Ernst, J. von Kanel, R. Boettger, S. Palliat Support Care 2019

Antipsychotics
Delirium
Hyperactive
Hypoactive
Management of delirium
Psychotropics
Subtypes

Predisposing and precipitating factors for delirium in neurology: a prospective cohort study of 1487 patients Zipser, C. M. Deuel, J. Ernst, J. Schubert, M. Weller, M. von Kanel, R. Boettger, S. J Neurol 2019

Delirium
Neurology
Neuropsychiatry
Risk factor

Risk factors for postoperative delirium after spinal surgery: a systematic review and meta-analysis Zhu, C. Wang, B. Yin, J. Xue, Q. Gao, S. Xing, L. Wang, H. Liu, W. Liu, X. Aging Clin Exp Res 2019

Delirium
Postoperative
Risk factors
Spinal surgery

Dexmedetomidine for the prevention of postoperative delirium in elderly patients undergoing noncardiac surgery: A meta-analysis of randomized controlled trials Zeng, H. Li, Z. He, J. Fu, W. PLoS One 2019
Risk factors for delirium: Are therapeutic interventions part of it? Xing, J. Yuan, Z. Jie, Y. Liu, Y. Wang, M. Sun, Y. Neuropsychiatric Disease and Treatment 2019

arterial line
stomach tube
sedative agent
vasoactive agent
adult
aged
APACHE
article
artificial ventilation
bladder catheterization
catheter removal
clinical evaluation
clinical feature
clinical study
cohort analysis
controlled study
critically ill patient
delirium
disease association
early intervention
female
human
intensive care
intensive care unit
length of stay
major clinical study
male
observational study
prospective study
risk assessment
risk factor
treatment duration
tube removal
vein catheterization

Intraoperative hyperglycemia increases the incidence of postoperative delirium Windmann, V. Spies, C. Knaak, C. Wollersheim, T. Piper, S. K. Vorderwulbecke, G. Kurpanik, M. Kuenz, S. Lachmann, G. Minerva Anestesiol 2019
External Validation of Two Models to Predict Delirium in Critically Ill Adults Using Either the Confusion Assessment Method-ICU or the Intensive Care Delirium Screening Checklist for Delirium Assessment Wassenaar, A. Schoonhoven, L. Devlin, J. W. van Haren, F. M. P. Slooter, A. J. C. Jorens, P. G. van der Jagt, M. Simons, K. S. Egerod, I. Burry, L. D. Beishuizen, A. Matos, J. Donders, A. R. T. Pickkers, P. van den Boogaard, M. Crit Care Med 2019

adult
animal experiment
animal model
article
checklist
cohort analysis
controlled study
critically ill patient
female
intensive care psychosis
intensive care unit
male
nonhuman
prediction
prospective study
receiver operating characteristic
validation process

Risk Factors and Incidence of Postoperative Delirium in Patients Undergoing Laryngectomy Wang, Y. Yu, H. Qiao, H. Li, C. Chen, K. Shen, X. Otolaryngol Head Neck Surg 2019

head and neck cancer
laryngeal cancer
outcome
postoperative delirium

Regional cerebral oxygen saturation and postoperative delirium in endovascular surgery: a prospective cohort study Wang, X. Feng, K. Liu, H. Liu, Y. Ye, M. Zhao, G. Wang, T. Trials 2019

Delirium
Regional cerebral oxygen saturation
rSO2

The impact of analgosedation on mortality and delirium in critically ill patients: A systematic review and meta-analysis Wang, C. T. Mao, Y. Zhao, L. Ma, B. Intensive Crit Care Nurs 2019

Analgesia-based sedation
Analgesia-first sedation
Analogsedation
Critically ill patients
Delirium
Meta-analysis
Mortality
No sedation
Systematic review

Incidence and risk factors of postoperative delirium in patients admitted to the ICU after elective intracranial surgery: A prospective cohort study Wang, C. M. Huang, H. W. Wang, Y. M. He, X. Sun, X. M. Zhou, Y. M. Zhang, G. B. Gu, H. Q. Zhou, J. X. Eur J Anaesthesiol 2019
Association between preoperative nutritional status and postoperative delirium in individuals with coronary artery bypass graft surgery: A prospective cohort study Velayati, A. Vahdat Shariatpanahi, M. Shahbazi, E. Vahdat Shariatpanahi, Z. Nutrition 2019

adductor pollicis muscle
adult
arm circumference
article
body mass
cohort analysis
confusion assessment
controlled study
coronary artery bypass graft
coronary artery bypass surgery
disease association
disease severity
female
general health status assessment
high risk population
human
intensive care unit
major clinical study
male
malnutrition
mental disease assessment
muscle thickness
nutritional assessment
Nutritional Risk Screening 2002
nutritional status
observational study
postoperative delirium
preoperative period
prevalence
priority journal
prospective study
risk reduction
skeletal muscle
skinfold thickness
subjective global assessment
triceps brachii muscle

Prevalence and risk factors for delirium in elderly patients with severe burns: a retrospective cohort study van Yperen, D. T. Raats, J. W. Dokter, J. Ziere, G. Roukema, G. R. van Baar, M. E. van der Vlies, C. H. J Burn Care Res 2019

Elderly
burns
delirium
prevalence
risk factors

Delirium After Transcatheter Aortic Valve Implantation Under General Anesthesia: Incidence, Predictors, and Relation to Long-Term Survival van der Wulp, K. van Wely, M. van Heijningen, L. van Bakel, B. Schoon, Y. Verkroost, M. Gehlmann, H. Van Garsse, L. Vart, P. Kievit, P. Rikkert, M. O. Morshuis, W. van Royen, N. J Am Geriatr Soc 2019

general anesthesia
postoperative delirium
survival
transcatheter aortic valve implantation

Impact of a Premorbid Psychiatric Disorder on the Incidence of Delirium during ICU Stay, Morbidity, and Long-Term Mortality van der Kuur, A. Bethlehem, C. Bruins, N. de Jager, C. van Alst, C. Haagsma, O. G. Keijzers, A. Boerma, E. C. Crit Care Res Pract 2019
Identifying determinants for the application of physical or chemical restraint in the management of psychomotor agitation on the critical care unit Teece, A. Baker, J. Smith, H. J Clin Nurs 2019

agitation
critical care
decision-making
delirium
intensive care
nursing
restraint

Impact of a nurse engagement intervention on pain, agitation and delirium assessment in a community intensive care unit Tan, C. M. Camargo, M. Miller, F. Ross, K. Maximous, R. Yung, P. Marshall, C. Fleming, D. Law, M. Tsang, J. L. BMJ Open Qual 2019

critical care
healthcare quality improvement
nurses
performance measures
quality improvement

Predictors of delirium after cardiac surgery in patients with sleep disordered breathing Tafelmeier, M. Knapp, M. Lebek, S. Floerchinger, B. Camboni, D. Creutzenberg, M. Wittmann, S. Zeman, F. Schmid, C. Maier, L. S. Wagner, S. Arzt, M. Eur Respir J 2019
The relationship between obstructive sleep apnoea and postoperative delirium and pain: an observational study of a surgical cohort Strutz, P. K. Kronzer, V. Tzeng, W. Arrington, B. McKinnon, S. L. Ben Abdallah, A. Haroutounian, S. Avidan, M. S. Anaesthesia 2019

delirium
pain, postoperative
sleep apnoea, obstructive

Ultra-brief Screeners for Detecting Delirium Superimposed on Dementia Steensma, E. Zhou, W. Ngo, L. Gallagher, J. Inouye, S. Leslie, D. Boltz, M. Kolanowski, A. Mion, L. Marcantonio, E. R. Fick, D. J Am Med Dir Assoc 2019

Delirium
dementia
screening tools

Etiology and Related Factors of Postoperative Delirium in Orthopedic Surgery Song, K. J. Ko, J. H. Kwon, T. Y. Choi, B. W. Clin Orthop Surg 2019

Delirium
Etiology
Orthopedic surgery
Risk factor
was reported.

Preoperative transcranial Doppler and cerebral oximetry as predictors of delirium following valvular heart surgery: a case-control study Soh, S. Shim, J. K. Song, J. W. Choi, N. Kwak, Y. L. J Clin Monit Comput 2019

Cardiac surgical procedures
Delirium
Heart valve diseases
Spectroscopy, Near-infrared
Ultrasonography, Doppler, Transcranial

Identification of Patients With High Mortality Risk and Prediction of Outcomes in Delirium by Bispectral EEG Shinozaki, G. Bormann, N. L. Chan, A. C. Zarei, K. Sparr, N. A. Klisares, M. J. Jellison, S. S. Heinzman, J. T. Dahlstrom, E. B. Duncan, G. N. Gaul, L. N. Wanzek, R. J. Cramer, E. M. Wimmel, C. G. Sabbagh, S. Yuki, K. Weckmann, M. T. Yamada, T. Karam, M. J Clin Psychiatry 2019
Postoperative Delirium Is Associated with Long-term Decline in Activities of Daily Living Shi, Z. Mei, X. Li, C. Chen, Y. Zheng, H. Wu, Y. Zheng, H. Liu, L. Marcantonio, E. R. Xie, Z. Shen, Y. Anesthesiology 2019
Managing Delirium and Agitation in the Older Emergency Department Patient: The ADEPT Tool Shenvi, C. Kennedy, M. Austin, C. A. Wilson, M. P. Gerardi, M. Schneider, S. Ann Emerg Med 2019
Delirium detection in older acute medical inpatients: a multicentre prospective comparative diagnostic test accuracy study of the 4AT and the confusion assessment method Shenkin, S. D. Fox, C. Godfrey, M. Siddiqi, N. Goodacre, S. Young, J. Anand, A. Gray, A. Hanley, J. MacRaild, A. Steven, J. Black, P. L. Tieges, Z. Boyd, J. Stephen, J. Weir, C. J. MacLullich, A. M. J. BMC Med 2019

*4at
*Confusion assessment method (CAM)
*Delirium
*Diagnostic test accuracy
*Hospital
*Sensitivity
*Specificity

Occurrence Rate of Delirium in Acute Stroke Settings: Systematic Review and Meta-Analysis Shaw, R. C. Walker, G. Elliott, E. Quinn, T. J. Stroke 2019

delirium
humans
risk
stroke
systematic review

Delirium in an Acute Stroke Setting, Occurrence, and Risk Factors Shaw, R. Drozdowska, B. Taylor-Rowan, M. Elliott, E. Cuthbertson, G. Stott, D. J. Quinn, T. J. Stroke 2019

cognitive dysfunction
delirium
humans
odds ratio
stroke

The relationship between serum cobalamin, folic acid, and homocysteine and the risk of post-cardiac surgery delirium Shariatpanahi, M. V. Velayati, A. Jamalian, S. A. Babevaynejad, M. Shariatpanahi, Z. V. Neuropsychiatric Disease and Treatment 2019

cobalamin
folic acid
homocysteine
adult
aged
amino acid blood level
article
cardiopulmonary bypass
cohort analysis
controlled study
coronary artery bypass graft
enzyme immunoassay
female
folic acid blood level
hospital admission
human
intensive care unit
major clinical study
male
pathophysiology
population research
postoperative delirium
postoperative period
prospective study
surgical risk
vitamin blood level

The effect of volunteers' care and support on the health outcomes of older adults in acute care: A systematic scoping review Saunders, R. Seaman, K. Graham, R. Christiansen, A. J Clin Nurs 2019

Volunteers
clinical outcomes
confusion
frailty
hospital
nursing
older adults

Mitochondrial DNA Haplogroups and Delirium During Sepsis Samuels, D. C. Hulgan, T. Fessel, J. P. Billings, F. T. th Thompson, J. L. Chandrasekhar, R. Girard, T. D. Crit Care Med 2019
Effect of Flexible Family Visitation on Delirium Among Patients in the Intensive Care Unit: The ICU Visits Randomized Clinical Trial Rosa, R. G. Falavigna, M. da Silva, D. B. Sganzerla, D. Santos, M. M. S. Kochhann, R. de Moura, R. M. Eugenio, C. S. Haack, Tdsr Barbosa, M. G. Robinson, C. C. Schneider, D. de Oliveira, D. M. Jeffman, R. W. Cavalcanti, A. B. Machado, F. R. Azevedo, L. C. JAMA 2019

Anxiety
Brazil
Burnout, Professional
Critical Care/psychology
Cross-Over Studies
Delirium/*prevention & control
Depression
Family/*psychology
Female
Health Education
Hospitalization
Humans
Incidence
Intensive Care Units/*organization & administration
Male
Middle Aged
Time Factors
*Visitors to Patients

Deconstructing Poststroke Delirium in a Prospective Cohort of Patients With Intracerebral Hemorrhage Reznik, M. E. Drake, J. Margolis, S. A. Moody, S. Murray, K. Costa, S. Mahta, A. Wendell, L. C. Thompson, B. B. Rao, S. S. Barrett, A. M. Boukrina, O. Daiello, L. A. Asaad, W. F. Furie, K. L. Jones, R. N. Crit Care Med 2019
Impact of intraoperative blood pressure, blood pressure fluctuation, and pulse pressure on postoperative delirium in elderly patients with hip fracture: A prospective cohort study Radinovic, K. Markovic Denic, L. Milan, Z. Cirkovic, A. Baralic, M. Bumbasirevic, V. Injury 2019

Blood pressure
Clinical outcomes
Hip fracture
Postoperative delirium
Pulse pressure

Economic impact of delirium in Australia: a cost of illness study Pezzullo, L. Streatfeild, J. Hickson, J. Teodorczuk, A. Agar, M. R. Caplan, G. A. BMJ Open 2019

delirium & cognitive disorders
dementia
health economics

Delirium Predisposing and Triggering Factors in Nursing Home Residents: A Cohort Trial-Nested Case-Control Study Pérez-Ros, P. Martínez-Arnau, F. M. Baixauli-Alacreu, S. Caballero-Pérez, M. García-Gollarte, J. F. Tarazona-Santabalbina, F. Journal of Alzheimer's Disease 2019

urinary catheter
antidepressant agent
anxiolytic agent
cholinergic receptor blocking agent
neuroleptic agent
aged
anemia
article
autoimmune disease
Barthel index
case control study
cerebrovascular accident
cognitive defect
cohort analysis
controlled study
daily life activity
delirium
dementia
dependent personality disorder
depression
diabetes mellitus
disease predisposition
dysphagia
epilepsy
female
follow up
geriatric assessment
Geriatric Depression Scale
glomerulus filtration rate
hearing impairment
hospital admission
human
hypoglycemia
kidney failure
major clinical study
male
Mini Mental State Examination
nursing home patient
pain
Parkinson disease
pneumonia
predictive value
priority journal
urinary tract infection
urine incontinence
very elderly
visual impairment

Preoperative C-Reactive Protein/Albumin Ratio, a Risk Factor for Postoperative Delirium in Elderly Patients After Total Joint Arthroplasty Peng, J. Wu, G. Chen, J. Chen, H. Journal of Arthroplasty 2019

aged
area under the curve
arthroplasty
article
brain dysfunction
controlled study
diagnosis
diagnostic test accuracy study
epidural anesthesia
female
human
incidence
laboratory test
major clinical study
male
multivariate logistic regression analysis
postoperative delirium
preoperative evaluation
receiver operating characteristic
risk factor
sensitivity and specificity
albumin
biological marker
C reactive protein
endogenous compound

Combination of lithium and electroconvulsive therapy (ECT) is associated with higher odds of delirium and cognitive problems in a large national sample across the United States Patel, R. S. Bachu, A. Youssef, N. A. Brain Stimul 2019

Bipolar disorder
Cognitive side effects
Delirium
Depression
Electroconvulsive therapy
Lithium
Major depressive disorder
Treatment-resistant depression

The long-term prognosis of patients with delirium in the acute phase of stroke: PRospective Observational POLIsh Study (PROPOLIS) Pasinska, P. Wilk, A. Kowalska, K. Szyper-Maciejowska, A. Klimkowicz-Mrowiec, A. J Neurol 2019

Delirium
Long-term prognosis
Mortality
Stroke

Postoperative Delirium is Associated with Negative Outcomes and Long-Term Mortality in Elderly Koreans: A Retrospective Observational Study Park, E. A. Kim, M. Y. Medicina (Kaunas) 2019

delirium
elderly
mortality
outcome
surgery

Development of a Tool for the Assessment of Nurses' Attitudes Toward Delirium Papastavrou, E. Papaioannou, M. Evripidou, M. Tsangari, H. Kouta, C. Merkouris, A. J Nurs Meas 2019

attitude
delirium
nursing
validation

The risk factors associated with delirium after lumbar spine surgery in elderly patients Pan, Z. Huang, K. Huang, W. Kim, K. H. Wu, H. Yu, Y. Kim, K. N. Yi, S. Shin, D. A. Vora, D. Gragnaniello, C. Phan, K. Tasiou, A. Winder, M. J. Koga, H. Azimi, P. Kang, S. Y. Ha, Y. Quantitative Imaging in Medicine and Surgery 2019

angiotensin receptor antagonist
antihistaminic agent
benzodiazepine derivative
C reactive protein
cholinergic receptor blocking agent
dopamine receptor stimulating agent
hydroxymethylglutaryl coenzyme A reductase inhibitor
hypnotic agent
opiate
psychotropic agent
aged
article
brain hemorrhage
brain infarction
cerebrovascular accident
controlled study
dementia
diffusion weighted imaging
female
human
incidence
laminectomy
lumbar spine
magnetic resonance angiography
major clinical study
male
mild cognitive impairment
Mini Mental State Examination
operation duration
operative blood loss
parkinsonism
postoperative delirium
preoperative period
prospective study
risk factor
sex difference
spinal cord decompression
spine fusion
spine surgery
susceptibility weighted imaging
transient ischemic attack
very elderly

Incidence, risk factors, and cumulative risk of delirium among ICU patients: A case-control study Pan, Y. Yan, J. Jiang, Z. Luo, J. Zhang, J. Yang, K. International Journal of Nursing Sciences 2019

analgesic agent
sedative agent
aged
APACHE
article
artificial ventilation
case control study
controlled study
delirium
diagnostic accuracy
diagnostic test accuracy study
female
hospitalization
human
incidence
intensive care unit
length of stay
major clinical study
male
mental disease assessment
receiver operating characteristic
retrospective study
Richmond Agitation Sedation Scale
risk assessment
risk factor
sensitivity and specificity
very elderly