What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Interventions for preventing intensive care unit delirium in adults.
- Authors
- Herling, S. F. Greve, I. E. Vasilevskis, E. E. Egerod, I. Bekker Mortensen, C. Møller, A. M. Svenningsen, H. Thomsen, T.
- Year
- 2018
- Journal
- Cochrane Database of Systematic Reviews
- Abstract
Background: Delirium is defined as a disturbance in attention, awareness and cognition with reduced ability to direct, focus, sustain and shift attention, and reduced orientation to the environment. Critically ill patients in the intensive care unit (ICU) frequently develop ICU delirium. It can profoundly affect both them and their families because it is associated with increased mortality, longer duration of mechanical ventilation, longer hospital and ICU stay and long-term cognitive impairment. It also results in increased costs for society. Objectives: To assess existing evidence for the effect of preventive interventions on ICU delirium, in-hospital mortality, the number of delirium- and coma-free days, ventilator-free days, length of stay in the ICU and cognitive impairment. Search methods: We searched CENTRAL, MEDLINE, Embase, BIOSIS, International Web of Science, Latin American Caribbean Health Sciences Literature, CINAHL from 1980 to 11 April 2018 without any language limits. We adapted the MEDLINE search for searching the other databases. Furthermore, we checked references, searched citations and contacted study authors to identify additional studies. We also checked the following trial registries: Current Controlled Trials; ClinicalTrials.gov; and CenterWatch.com (all on 24 April 2018). Selection criteria: We included randomized controlled trials (RCTs) of adult medical or surgical ICU patients receiving any intervention for preventing ICU delirium. The control could be standard ICU care, placebo or both. We assessed the quality of evidence with GRADE. Data collection and analysis: We checked titles and abstracts to exclude obviously irrelevant studies and obtained full reports on potentially relevant ones. Two review authors independently extracted data. If possible we conducted meta-analyses, otherwise we synthesized data narratively. Main results: The electronic search yielded 8746 records. We included 12 RCTs (3885 participants) comparing usual care with the following interventions: commonly used drugs (four studies); sedation regimens (four studies); physical therapy or cognitive therapy, or both (one study); environmental interventions (two studies); and preventive nursing care (one study). We found 15 ongoing studies and five studies awaiting classification. The participants were 48 to 70 years old; 48% to 74% were male; the mean acute physiology and chronic health evaluation (APACHE II) score was 14 to 28 (range 0 to 71; higher scores correspond to more severe disease and a higher risk of death). With the exception of one study, all participants were mechanically ventilated in medical or surgical ICUs or mixed. The studies were overall at low risk of bias. Six studies were at high risk of detection bias due to lack of blinding of outcome assessors. We report results for the two most commonly explored approaches to delirium prevention: pharmacologic and a non-pharmacologic intervention. Haloperidol versus placebo (two RCTs, 1580 participants) The event rate of ICU delirium was measured in one study including 1439 participants. No difference was identified between groups, (risk ratio (RR) 1.01, 95% confidence interval (CI) 0.87 to 1.17) (moderate-quality evidence). Haloperidol versus placebo neither reduced or increased in-hospital mortality, (RR 0.98, 95% CI 0.80 to 1.22; 2 studies; 1580 participants (moderate-quality evidence)); the number of delirium- and coma-free days, (mean difference (MD) -0.60, 95% CI -1.37 to 0.17; 2 studies, 1580 participants (moderate-quality of evidence)); number of ventilator-free days (mean 23.8 (MD -0.30, 95% CI -0.93 to 0.33) 1 study; 1439 participants, (high-quality evidence)); length of ICU stay, (MD 0.18, 95% CI -0.60 to 0.97); 2 studies, 1580 participants; high-quality evidence). None of the studies measured cognitive impairment. In one study there were three serious adverse events in the intervention group and five in the placebo group; in the other there were five serious adverse events and three patients died, one in each group. None of the serious adverse eve ts were judged to be related to interventions received (moderate-quality evidence). Physical and cognitive therapy interventions (one study, 65 participants) The study did not measure the event rate of ICU delirium. A physical and cognitive therapy intervention versus standard care neither reduced nor increased in-hospital mortality, (RR 0.94, 95% CI 0.40 to 2.20, I2; = 0; 1 study, 65 participants; very low-quality evidence); the number of delirium- and coma-free days, (MD -2.8, 95% CI -10.1 to 4.6, I2; = 0; 1 study, 65 participants; very low-quality evidence); the number of ventilator-free days (within the first 28/30 days) was median 27.4 (IQR 0 to 29.2) and 25 (IQR 0 to 28.9); 1 study, 65 participants; very low-quality evidence, length of ICU stay, (MD 1.23, 95% CI -0.68 to 3.14, I2; = 0; 1 study, 65 participants; very low-quality evidence); cognitive impairment measured by the MMSE: Mini-Mental State Examination with higher scores indicating better function, (MD 0.97, 95% CI -0.19 to 2.13, I2; = 0; 1 study, 30 participants; very low-quality evidence); or measured by the Dysexecutive questionnaire (DEX) with lower scores indicating better function (MD -8.76, 95% CI -19.06 to 1.54, I2; = 0; 1 study, 30 participants; very low-quality evidence). One patient experienced acute back pain accompanied by hypotensive urgency during physical therapy. Authors’ conclusions: There is probably little or no difference between haloperidol and placebo for preventing ICU delirium but further studies are needed to increase our confidence in the findings. There is insufficient evidence to determine the effects of physical and cognitive intervention on delirium. The effects of other pharmacological interventions, sedation, environmental, and preventive nursing interventions are unclear and warrant further investigation in large multicentre studies. Five studies are awaiting classification and we identified 15 ongoing studies, evaluating pharmacological interventions, sedation regimens, physical and occupational therapy combined or separately, and environmental interventions, that may alter the conclusions of the review in future.
- PMID
- Keywords
ISRCTN83567338
NCT00095251
NCT00466492
NCT00675363
NCT00824239
NCT01270269
NCT01274819
NCT01739933
NCT01785290
NCT01791296
NCT0196768
NCT01983800
NCT02245256
NCT02548923
NCT02612948
NCT02615340
NCT02932358
NCT03002701
NCT03095443
NCT03125252
NCT03172897
NCT03215745
dexmedetomidine
haloperidol
lorazepam
placebo
adult
APACHE
artificial ventilation
bradycardia
cognitive defect
cognitive therapy
coma
critically ill patient
delirium
environmental intervention
health care cost
hospital mortality
human
intensive care unit
intention to treat analysis
intervention study
length of stay
nursing intervention
outcome assessment
physiotherapy
priority journal
randomized controlled trial (topic)
review
sedation
seizure
sensitivity analysis
treatment duration
ventilator weaning
- Page(s)
- Volume
- 2018
- Issue
- 11
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| American Society for Enhanced Recovery and Perioperative quality initiative joint consensus statement on the role of neuromonitoring in perioperative outcomes: Electroencephalography | Chan, M. T. V. Hedrick, T. L. Egan, T. D. García, P. S. Koch, S. Purdon, P. L. Ramsay, M. A. Miller, T. E. McEvoy, M. D. Gan, T. J. Hughes, C. G. Boncyk, C. S. Culley, D. J. Fleisher, L. A. Leung, J. M. McDonagh, D. L. Thiele, R. H. Shaw, A. Bartels, K. | Anesthesia and Analgesia | 2020 |
anesthesiologist |
| Evidence-based clinical practice guidelines for the management of sedoanalgesia and delirium in critically ill adult patients | Celis-Rodríguez, E. Díaz Cortés, J. C. Cárdenas Bolívar, Y. R. Carrizosa González, J. A. Pinilla, D. I. Ferrer Záccaro, L. E. Birchenall, C. Caballero López, J. Argüello, B. M. Castillo Abrego, G. Castorena Arellano, G. Dueñas Castell, C. Jáure | Med Intensiva | 2020 |
Agitación |
| Patient care during the COVID-19 pandemic: do not leave delirium behind | Castro, R. E. V. Garcez, F. B. Avelino-Silva, T. J. | Braz J Psychiatry | 2020 | |
| The financial and social costs of delirium | Caplan, G. A. Teodorczuk, A. Streatfeild, J. Agar, M. R. | European Geriatric Medicine | 2020 |
cost control |
| Clinical impression for identification of vulnerable older patients in the emergency department | Calf, A. H. Lubbers, S. van den Berg, A. A. van den Berg, E. Jansen, C. J. van Munster, B. C. de Rooij, S. E. Ter Maaten, J. C. | Eur J Emerg Med | 2020 | |
| Is Delirium Pediatric Confusion Assessment Method Tools Confiable? | Caino de Oliveira, F. R. Ribeiro de Araujo, O. Brunow de Carvalho, W. | Pediatr Crit Care Med | 2020 |
Brazil |
| Research in brief: Inpatient hip fractures and nomenclature of delirium and acute encephalopathy | Cacciottolo, T. M. Ferrigan, L. | Clin Med (Lond) | 2020 | |
| Prolonged Confusional state as first manifestation of COVID-19 | Butt, I. Sawlani, V. Geberhiwot, T. | Ann Clin Transl Neurol | 2020 |
Covid-19 |
| Delirium After Withdrawal From Valerian Root: A Case Report | Burke, H. Jiang, S. Chatham, P. Stern, T. A. | Psychosomatics | 2020 | |
| Deciphering delirium through semantics: a selective synopsis | Bugiani, O. | Neurol Sci | 2020 |
Ageing |
| Predicting incident delirium diagnoses using data from primary-care electronic health records | Bowman, K. Jones, L. Masoli, J. Mujica-Mota, R. Strain, D. Butchart, J. Valderas, J. M. Fortinsky, R. H. Melzer, D. Delgado, J. | Age Ageing | 2020 |
at home |
| Comparison of Self-Reported and Behavioral Pain Assessment Tools in Critically Ill Patients | Bouajram, R. H. Sebat, C. M. Love, D. Louie, E. L. Wilson, M. D. Duby, J. J. | J Intensive Care Med | 2020 |
Behavioral Pain Scale |
| Practical Training of Anesthesia Clinicians in Electroencephalogram-Based Determination of Hypnotic Depth of General Anesthesia | Bombardieri, A. M. Wildes, T. S. Stevens, T. Wolfson, M. Steinhorn, R. Ben Abdallah, A. Sleigh, J. Avidan, M. S. | Anesth Analg | 2020 |
Anesthesia, Inhalation |
| A multisite study of nurse-reported perceptions and practice of ABCDEF bundle components | Boehm, L. M. Pun, B. T. Stollings, J. L. Girard, T. D. Rock, P. Hough, C. L. Hsieh, S. J. Khan, B. A. Owens, R. L. Schmidt, G. A. Smith, S. Ely, E. W. | Intensive Crit Care Nurs | 2020 |
ABCDEF bundle |
| Cognitive impairment, clinical symptoms and functional disability in patients emerging from the minimally conscious state | Bodien, Y. G. Martens, G. Ostrow, J. Sheau, K. Giacino, J. T. | NeuroRehabilitation | 2020 |
adult |
| Effect of intravenous iron on functional outcomes in hip fracture: a randomised controlled trial | Bielza, R. Llorente, J. Thuissard, I. J. Andreu-Vázquez, C. Blanco, D. Sanjurjo, J. López, N. Herráez, M. R. Molano, C. Morales, A. Arias, E. Neira, M. Lung, A. Escalera, J. Portillo, L. Larrubia, Y. García, C. Zambrana, F. Gómez Cerezo, J. | Age Ageing | 2020 |
anaemia |
| Tapering with Pharmaceutical GHB or Benzodiazepines for Detoxification in GHB-Dependent Patients: A Matched-Subject Observational Study of Treatment-as-Usual in Belgium and The Netherlands | Beurmanjer, H. Luykx, J. J. De Wilde, B. van Rompaey, K. Buwalda, V. J. A. De Jong, C. A. J. Dijkstra, B. A. G. Schellekens, A. F. A. | CNS Drugs | 2020 | |
| Clinical characteristics and outcomes of inpatients with neurologic disease and COVID-19 in Brescia, Lombardy, Italy | Benussi, A. Pilotto, A. Premi, E. Libri, I. Giunta, M. Agosti, C. Alberici, A. Baldelli, E. Benini, M. Bonacina, S. Brambilla, L. Caratozzolo, S. Cortinovis, M. Costa, A. Piccinelli, S. C. Cottini, E. Cristillo, V. Delrio, I. Filosto, M. Gamba, M. Gazzina | Neurology | 2020 | |
| Palliative sedation: beliefs and decision-making among Spanish palliative care physicians | Benítez-Rosario, M. A. Ascanio-León, B. | Support Care Cancer | 2020 |
Cancer patients |
| A Tunisian version of the confusion assessment method for the intensive care unit (CAM-ICU): translation and validation | Ben Saida, I. Kortli, S. Amamou, B. Kacem, N. Ghardallou, M. Ely, E. W. Ben Saad, H. Boussarsar, M. | BMC Psychiatry | 2020 |
Critical illness |
| 'Socialised care futility' in the care of older people in hospital who call out repetitively: An ethnographic study | Beaver, J. Goldberg, S. E. Edgley, A. Harwood, R. H. | Int J Nurs Stud | 2020 |
Acute hospitals |
| Delirium in COVID-19: A case series and exploration of potential mechanisms for central nervous system involvement | Beach, S. R. Praschan, N. C. Hogan, C. Dotson, S. Merideth, F. Kontos, N. Fricchione, G. L. Smith, F. A. | Gen Hosp Psychiatry | 2020 |
Akinetic mutism |
| Prevalence of delirium in intensive care patients and association with sedoanalgesia, severity and mortality | Bastos, A. S. Beccaria, L. M. Silva, D. C. D. Barbosa, T. P. | Revista gaucha de enfermagem | 2020 |
adult |
| Antipsychotics and the Risk of Mortality or Cardiopulmonary Arrest in Hospitalized Adults | Basciotta, M. Zhou, W. Ngo, L. Donnino, M. Marcantonio, E. R. Herzig, S. J. | J Am Geriatr Soc | 2020 |
antipsychotics |
| Comprehensive analysis of in-hospital delirium after major surgical oncology procedures: A population-based study | Bandini, M. Marchioni, M. Preisser, F. Nazzani, S. Tian, Z. Graefen, M. Montorsi, F. Saad, F. Shariat, S. F. Schips, L. Briganti, A. Karakiewicz, P. I. | Can Urol Assoc J | 2020 |
adult |
| Sepsis Associated Delirium | Atterton, B. Paulino, M. C. Povoa, P. Martin-Loeches, I. | Medicina (Kaunas) | 2020 |
adult |
| Melatonin for delirium prevention in acute medically ill, and perioperative geriatric patients | Asleson, D. R. Chiu, A. W. | Aging Medicine | 2020 |
adult |
| The short- And long-term outcomes of esophagectomy for esophageal cancer in patients older than 75 years | Aoyama, T. Hara, K. Kazama, K. Atsumi, Y. Tamagawa, H. Tamagawa, A. MacHida, D. Komori, K. Maezawa, Y. Kano, K. Hashimoto, I. Oshima, T. Murakawa, M. Numata, M. Yukawa, N. Masuda, M. Rino, Y. | Anticancer Research | 2020 |
antineoplastic agent |
| National French survey of COVID-19 symptoms in people aged 70 and over | Annweiler, C. Sacco, G. Salles, N. Aquino, J. P. Gautier, J. Berrut, G. Guérin, O. Gavazzi, G. | Clin Infect Dis | 2020 | |
| COVID-19: ICU delirium management during SARS-CoV-2 pandemic-pharmacological considerations | Andrews, L. J. Benken, S. T. | Crit Care | 2020 |
Betacoronavirus |
| The Intersection of Architecture/Medicine/Quality and the Clinical Nurse Specialist: Designing for the Prevention of Delirium | Anderson, D. C. Jacoby, S. R. Scruth, E. A. | Clinical nurse specialist CNS | 2020 | |
| The Agents Intervening against Delirium in the Intensive Care Unit-Trial (AID-ICU trial):- a detailed statistical analysis plan | Andersen-Ranberg, N. Poulsen, L. M. Perner, A. Wetterslev, J. Mathiesen, O. Mortensen, C. B. Estrup, S. Ebdrup, B. H. Hästbacka, J. Citerio, G. Caballero, J. Morgan, M. P. G. Oxenbøll-Collet, M. Weber, S. O. Andreasen, A. S. Bestle, M. H. Pedersen, H. B | Acta Anaesthesiol Scand | 2020 | |
| A systematic review of the overlap of fluid biomarkers in delirium and advanced cancer-related syndromes | Amgarth-Duff, I. Hosie, A. Caplan, G. Agar, M. | BMC Psychiatry | 2020 |
Advanced cancer |
| Toward best practice methods for delirium biomarker studies: An international modified Delphi study | Amgarth-Duff, I. Hosie, A. Caplan, G. Agar, M. | Int J Geriatr Psychiatry | 2020 |
consensus |
| Preoperative cognitive dysfunction in older elective noncardiac surgical patients in South Africa | Amado, L. A. Perrie, H. Scribante, J. Ben-Israel, K. A. | Br J Anaesth | 2020 |
Mini-Cog |
| The etiology and age-related properties of patients with delirium in coronary intensive care unit and its effects on inhospital and follow up prognosis | Altay, S. Gürdoğan, M. Kaya, Ç Kardaş, F. Zeybey, U. Çakir, B. Ebik, M. Demir, M. | Ideggyogy Sz | 2020 |
delirium in coronary intensive care unit |
| A Unique Presentation of Delirium in a Patient with Otherwise Asymptomatic COVID-19 | Alkeridy, W. A. Almaghlouth, I. Alrashed, R. Alayed, K. Binkhamis, K. Alsharidi, A. Liu-Ambrose, T. | J Am Geriatr Soc | 2020 |
Covid-19 |
| Postoperative delirium after abdominal aortic surgery: after ICU discharge surveillance should extend to the surgical ward | Alessandri, F. Bilotta, F. | Minerva Anestesiol | 2020 | |
| The prevalence of emergence delirium and its associated factors among children at a postoperative unit: A retrospective cohort at a Middle Eastern hospital | Aldakhil, S. K. Salam, M. Albelali, A. A. Alkanhal, R. M. Alnemer, M. J. Alatassi, A. | Saudi J Anaesth | 2020 |
Anesthesia |
| Optimal goal of management of delirium in end-of-life cancer care | Akechi, T. | Lancet Oncol | 2020 | |
| Multiple Peri-Operative Complications are Associated with Reduced Long Term Amputation Free Survival Following Revascularisation for Lower Limb Peripheral Artery Disease: A Population Based Linked Data Study | Aitken, S. J. Randall, D. A. Noguchi, N. Blyth, F. M. Naganathan, V. | Eur J Vasc Endovasc Surg | 2020 |
Aged |
| Neurological manifestations and complications of COVID-19: A literature review | Ahmad, I. Rathore, F. A | J Clin Neurosci | 2020 |
Clinical features |
| The role of suvorexant in the prevention of delirium during acute hospitalization: A systematic review | Adams, A. D. Pepin, M. J. Brown, J. N. | J Crit Care | 2020 |
Belsomra |
| Quetiapine for delirium prophylaxis in high-risk critically ill patients | Abraham, M. P. Hinds, M. Tayidi, I. Jeffcoach, D. R. Corder, J. M. Hamilton, L. A. Lawson, C. M. Bollig, R. W. Heidel, R. E. Daley, B. J. Taylor, J. E. McMillen, J. C. | Surgeon | 2020 |
Delirium |
| Comparing outcomes after peripheral nerve block versus general anesthesia for lower extremity amputation: a nationwide exploratory retrospective cohort study in Japan | Abe, H. Sumitani, M. Matsui, H. Aso, S. Inoue, R. Fushimi, K. Uchida, K. Yasunaga, H. Yamada, Y. | Reg Anesth Pain Med | 2020 |
lower extremity |
| Development of delirium: Association with old age, severe burns, and intensive care | Abdelrahman, I. Vieweg, R. Irschik, S. Steinvall, I. Sjöberg, F. Elmasry, M. | Burns | 2020 |
Burns |
| Factors Associated With Postoperative Confusion and Prolonged Hospital Stay Following Deep Brain Stimulation Surgery for Parkinson Disease | Abboud, H. Genc, G. Saad, S. Thompson, N. Oravivattanakul, S. Alsallom, F. Yu, X. X. Floden, D. Gostkowski, M. Ahmed, A. Ezzeldin, A. Marouf, H. M. Mansour, O. Y. Fernandez, H. H. | Neurosurgery | 2020 |
Dbs |
| Mortality and complications after emergency laparotomy in patients above 80 years | Aakre, E. K. Ulvik, A. Hufthammer, K. O. Jammer, I. | Acta Anaesthesiol Scand | 2020 |
elderly |
| Evaluation of an emergency department falls pathway for older people: A patient chart review | O' Keeffe A O' Grady S Cronin, F. Dolan, C. O' Hea A O' Shea KL Naughton, C. | Int Emerg Nurs | 2020 | |
| Rapid in-person cognitive screening in the preoperative setting: Test considerations and recommendations from the Society for Perioperative Assessment and Quality Improvement (SPAQI) | Arias, F. Wiggins, M. Urman, R. D. Armstrong, R. Pfeifer, K. Bader, A. M. Libon, D. J. Chopra, A. Price, C. C. | Journal of Clinical Anesthesia | 2020 |
anesthesiology |
| Updated nomenclature of delirium and acute encephalopathy: statement of ten Societies | Slooter, A. J. C. Otte, W. M. Devlin, J. W. Arora, R. C. Bleck, T. P. Claassen, J. Duprey, M. S. Ely, E. W. Kaplan, P. W. Latronico, N. Morandi, A. Neufeld, K. J. Sharshar, T. MacLullich, A. M. J. Stevens, R. D. | Intensive Care Medicine | 2020 |
acute brain disease |
| Nonsedation or Light Sedation in Critically Ill, Mechanically Ventilated Patients | Olsen, H. T. Nedergaard, H. K. Strøm, T. Oxlund, J. Wian, K. A. Ytrebø, L. M. Kroken, B. A. Chew, M. Korkmaz, S. Lauridsen, J. T. Toft, P. | The New England journal of medicine | 2020 |
NCT01967680 |
| Ketamine Safety and Use in the Emergency Department for Pain and Agitation/Delirium: A Health System Experience | Mo, H. Campbell, M. J. Fertel, B. S. Lam, S. W. Wells, E. J. Casserly, E. Meldon, S. W. | The western journal of emergency medicine | 2020 |
adult |
| Impact of skeletal muscle mass on postoperative delirium in patients undergoing free flap repair after oral cancer resection | Makiguchi, T. Yamaguchi, T. Nakamura, H. Ogawa, M. Harimoto, N. Shirabe, K. Yokoo, S. | Journal of plastic surgery and hand surgery | 2020 |
adult |
| Identifying delirium in Parkinson disease: A pilot study | Lawson, R. A. Richardson, S. J. Yarnall, A. J. Burn, D. J. Allan, L. M. | International Journal of Geriatric Psychiatry | 2020 |
aged |
| Presurgical cognitive impairment is associated with postoperative delirium and postoperative cognitive dysfunction | Knaak, C. Brockhaus, W. R. Spies, C. Borchers, F. Piper, S. K. Radtke, F. M. Lachmann, G. | Minerva anestesiologica | 2020 |
aged |
| The effects of elective aortic repair, colorectal cancer surgery and subsequent postoperative delirium on long-term quality of life, cognitive functioning and depressive symptoms in older patients | Janssen, T. L. de Vries, J. Lodder, P. Faes, M. C. Ho, G. H. Gobardhan, P. D. van der Laan, L. | Aging & mental health | 2020 |
abdominal aortic aneurysm |
| American Society for Enhanced Recovery and Perioperative Quality Initiative Joint Consensus Statement on Postoperative Delirium Prevention | Hughes, C. G. Boncyk, C. S. Culley, D. J. Fleisher, L. A. Leung, J. M. McDonagh, D. L. Gan, T. J. McEvoy, M. D. Miller, T. E. | Anesthesia and analgesia | 2020 |
adult |
| Healthcare professionals' reports of cancer pain cues among older people with delirium: a qualitative-quantitative content analysis | Graham, C. A. Chaves, G. Harrison, R. Gauthier, L. R. Nissim, R. Zimmermann, C. Chan, V. Rodin, G. Stevens, B. Gagliese, L. | Journal of pain and symptom management | 2020 |
adult |
| Preoperative Cognitive Abnormality, Intraoperative Electroencephalogram Suppression, and Postoperative Delirium: A Mediation Analysis | Fritz, B. A. King, C. R. Ben Abdallah, A. Lin, N. Mickle, A. M. Budelier, T. P. Oberhaus, J. Park, D. Maybrier, H. R. Wildes, T. S. Avidan, M. S. Apakama, G. Aranake-Chrisinger, A. Bolzenius, J. Burton, J. Cui, V. Emmert, D. A. Goswami, S. Graetz, T. J. G | Anesthesiology | 2020 |
adult |
| Delirium screening and mortality in patients with dementia admitted to acute hospitals | Codling, D. Hood, C. Bassett, P. Smithard, D. Crawford, M. J. | Aging & mental health | 2020 |
aged |
| Do Neuroleptics Still Have a Role in Patients With Delirium? | Nikooie, R. Oh, E. S. Zhang, A. Robinson, K. A. Needham, D. M. | Annals of internal medicine | 2020 |
adult |
| Randomized clinical trial of intraoperative dexmedetomidine to prevent delirium in the elderly undergoing major non-cardiac surgery | Li, C. J. Wang, B. J. Mu, D. L. Hu, J. Guo, C. Li, X. Y. Ma, D. Wang, D. X. | British Journal of Surgery | 2020 |
ChiCTRIPR15007654 |
| Risk factors for adverse drug reactions in older inpatients of geriatric wards at admission: Multicenter study | Kojima, T. Matsui, T. Suzuki, Y. Takeya, Y. Tomita, N. Kozaki, K. Kuzuya, M. Rakugi, H. Arai, H. Akishita, M. | Geriatrics and Gerontology International | 2020 |
albumin |
| Real-world effectiveness of ramelteon and suvorexant for delirium prevention in 948 patients with delirium risk factors | Hatta, K. Kishi, Y. Wada, K. Takeuchi, T. Hashimoto, N. Suda, K. Taira, T. Tsuchida, K. Ohmori, T. Akizuki, N. Nishio, Y. Nakanishi, Y. Usui, C. Kurata, A. Horikawa, N. Eguchi, H. Ito, S. Muto, H. Nakamura, H. Uchimura, N. | Journal of Clinical Psychiatry | 2020 |
corticosteroid derivative |
| Independent Association Between Type of Intraoperative Blood Transfusion and Postoperative Delirium After Complex Spinal Fusion for Adult Deformity Correction | Elsamadicy, A. A. Adil, S. M. Charalambous, L. Drysdale, N. Koo, A. B. Lee, M. Kundishora, A. J. Camara-Quintana, J. Kolb, L. Laurans, M. Abbed, K. Karikari, I. O. | Spine | 2020 |
adult |
| Practices related to assessment of sedation, analgesia and delirium among critical care pediatricians in Brazil | Colleti Junior, J. Araujo, O. R. Andrade, A. B. Carvalho, W. B. | Einstein (Sao Paulo, Brazil) | 2020 |
analgesia |
| Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study | Chen, N. Zhou, M. Dong, X. Qu, J. Gong, F. Han, Y. Qiu, Y. Wang, J. Liu, Y. Wei, Y. Xia, J. Yu, T. Zhang, X. Zhang, L. | The Lancet | 2020 |
adult |
| Association between postoperative delirium and mortality in elderly patients undergoing hip fractures surgery: a meta-analysis | Bai, J. Liang, Y. Zhang, P. Liang, X. He, J. Wang, J. Wang, Y. | Osteoporosis International | 2020 |
article |
| Impact of frailty on short-term outcomes in patients undergoing transsphenoidal pituitary surgery | Asemota, A. O. Gallia, G. L. | Journal of Neurosurgery | 2020 |
acute heart infarction |
| Randomised controlled trial to investigate the relationship between mild hypercapnia and cerebral oxygen saturation in patients undergoing major surgery | Wong, C. Churilov, L. Cowie, D. Tan, C. O. Hu, R. Tremewen, D. Pearce, B. Pillai, P. Karalapillai, D. Bellomo, R. Weinberg, L. | BMJ Open | 2020 |
delirium |
| Establishment and validation of a delirium prediction model for neurosurgery patients in intensive care | Wang, J. Ji, Y. Wang, N. Chen, W. Bao, Y. Qin, Q. Ma, C. Xiao, Q. Li, S. | Int J Nurs Pract | 2020 |
delirium |
| Early mobilisation after transfemoral transcatheter aortic valve implantation: results of the MobiTAVI trial | Vendrik, J. Vlastra, W. van Mourik, M. S. Delewi, R. Beijk, M. A. Lemkes, J. Wykrzykowska, J. J. de Winter, R. J. Henriques, J. S. Piek, J. J. Vis, M. M. Koch, K. T. Baan, J., Jr. | Neth Heart J | 2020 |
Ambulation |
| Influence of sedation on delirium recognition in critically ill patients: A multinational cohort study | van den Boogaard, M. Wassenaar, A. van Haren, F. M. P. Slooter, A. J. C. Jorens, P. G. van der Jagt, M. Simons, K. S. Egerod, I. Burry, L. D. Beishuizen, A. Pickkers, P. Devlin, J. W. | Aust Crit Care | 2020 |
Assessment |
| Intraoperative reduction of vasopressors using processed electroencephalographic monitoring in patients undergoing elective cardiac surgery: a randomized clinical trial | Sponholz, C. Schuwirth, C. Koenig, L. Hoyer, H. Coldewey, S. M. Schelenz, C. Doenst, T. Kortgen, A. Bauer, M. | J Clin Monit Comput | 2020 |
Adverse events |
| Enhanced rehabilitation and care models for adults with dementia following hip fracture surgery | Smith, T. O. Gilbert, A. W. Sreekanta, A. Sahota, O. Griffin, X. L. Cross, J. L. Fox, C. Lamb, S. E. | Cochrane Database Syst Rev | 2020 | |
| Prospective Evaluation of Delirium in Geriatric Patients Undergoing Emergency General Surgery | Saljuqi, A. T. Hanna, K. Asmar, S. Tang, A. Zeeshan, M. Gries, L. Ditillo, M. Kulvatunyou, N. Castanon, L. Joseph, B. | J Am Coll Surg | 2020 | |
| Predisposing and Precipitating Factors Associated With Postoperative Delirium in Patients Undergoing Cardiac Surgery at a Veterans Affairs Medical Center: A Pilot Retrospective Analysis | Russell, M. D. Pinkerton, C. Sherman, K. A. Ebert, T. J. Pagel, P. S. | J Cardiothorac Vasc Anesth | 2020 |
Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition |
| Dopaminergic Hyperactivity in Neurological Patients with Delirium | Ramirez-Bermudez, J. Perez-Neri, I. Montes, S. Nente, F. Ramirez-Abascal, M. Carrillo-Mezo, R. Perez-Esparza, R. Soto-Hernandez, J. L. Espinola-Nadurille, M. Bayliss, L. De Jesus Flores Rivera, J. Rios, C. | Arch Med Res | 2020 |
Autoimmune limbic encephalitis |
| Effects of intravenous and mask induction on post-operative emergence delirium in pediatric patients undergoing tonsillectomy with or without adenoidectomy | Peker, K. Polat, R. | Ir J Med Sci | 2020 |
Intravenous induction |
| Safety and Tolerability of Rapid Administration Undiluted Levetiracetam | Morgan, O. Medenwald, B. | Neurocrit Care | 2020 |
Anticonvulsants |
| New use of psychotropic medication after hospitalization among people with dementia | Mollers, T. Perna, L. Stocker, H. Ihle, P. Schubert, I. Schottker, B. Frolich, L. Brenner, H. | Int J Geriatr Psychiatry | 2020 |
claims data |
| A logistic regression analysis comparing minimalistic approach and intubation anaesthesia in patients undergoing transfemoral transcatheter aortic valve replacement | Maier, A. Hammerich, B. Humburger, F. Brieschal, T. Heidt, T. Bothe, W. Schrofel, H. Kaier, K. Zehender, M. Reinohl, J. Bode, C. von Zur Muhlen, C. Stachon, P. | PLoS One | 2020 | |
| Anticipating Postoperative Delirium During Burst Suppression Using Electroencephalography | Ma, O. Crepeau, A. Z. Dutta, A. Bliss, D. | IEEE Trans Biomed Eng | 2020 |
adult |
| Can haloperidol prophylaxis reduce the incidence of delirium in critically ill patients in intensive care units? A systematic review and meta-analysis | Lin, P. Zhang, J. Shi, F. Liang, Z. A. | Heart Lung | 2020 |
Delirium |
| Benzodiazepines for treatment of patients with delirium excluding those who are cared for in an intensive care unit | Li, Y. Ma, J. Jin, Y. Li, N. Zheng, R. Mu, W. Wang, J. Si, J. H. Chen, J. Shang, H. C. | Cochrane Database Syst Rev | 2020 | |
| Delirium prevalence and prevention in patients with acute brain injury: A prospective before-and-after intervention study | Larsen, L. K. Moller, K. Petersen, M. Egerod, I. | Intensive Crit Care Nurs | 2020 |
Brain injuries |
| Postoperative anaemia might be a risk factor for postoperative delirium and prolonged hospital stay: A secondary analysis of a prospective cohort study | Kunz, J. V. Spies, C. D. Bichmann, A. Sieg, M. Mueller, A. | PLoS One | 2020 | |
| Development of a Simple and Practical Delirium Screening Tool for Use in Surgical Wards | Kubota, K. Suzuki, A. Ohde, S. Yamada, U. Fujitani, I. Koitabashi, A. | J Nurs Res | 2020 |
adult |
| Psychometric evaluation of the family caregiver ICU delirium knowledge questionnaire | Krewulak, K. D. Bull, M. J. Ely, E. W. Stelfox, H. T. Fiest, K. M. | BMC Health Serv Res | 2020 |
Critical care |
| The Impact of Acute Kidney Injury in the Perioperative Period on the Incidence of Postoperative Delirium in Patients Undergoing Coronary Artery Bypass Grafting-Observational Cohort Study | Kotfis, K. Slozowska, J. Listewnik, M. Szylinska, A. Rotter, I. | Int J Environ Res Public Health | 2020 |
Aki |
| Delirium point prevalence studies in inpatient settings: A systematic review and meta-analysis | Koirala, B. Hansen, B. R. Hosie, A. Budhathoki, C. Seal, S. Beaman, A. Davidson, P. M. | J Clin Nurs | 2020 |
delirium |
| Validity and Reliability of the Memorial Delirium Assessment Scale-Thai Version (MDAS-T) for Assessment of Delirium in Palliative Care Patients | Klankluang, W. Pukrittayakamee, P. Atsariyasing, W. Siriussawakul, A. Chanthong, P. Tongsai, S. Tayjasanant, S. | Oncologist | 2020 |
Delirium |
| The Impact of an Attending Intensivist on the Clinical Outcomes of Patients Admitted to the Cardiac Surgical Intensive Care Unit after Coronary Artery Bypass Grafting | Kim, D. J. Sohn, B. Kim, H. Chang, H. W. Lee, J. H. Kim, J. S. Lim, C. Park, K. H. | Korean J Thorac Cardiovasc Surg | 2020 |
Coronary artery bypass grafting |
| Working Collaboratively: Outcomes of Geriatrician Input in Older Patients Undergoing Emergency Laparotomy in a District General Hospital | Khan, K. A. Subramanian, T. Richters, M. Mubarik, A. Saad Abdalla Al-Zawi, A. Thorn, C. C. Chalstrey, S. Gunasekera, S. | Cureus | 2020 |
ageing & frailty |
| Postoperative delirium: the findings from a multidisciplinary survey | Jin, Z. Rahman, A. Pattnaik, S. Smith, M. | Psychogeriatrics | 2020 |
education |
| Postoperative delirium after reconstructive surgery for oral tumor: a retrospective clinical study | Ishibashi-Kanno, N. Takaoka, S. Nagai, H. Okubo-Sato, M. Fukuzawa, S. Uchida, F. Yamagata, K. Yanagawa, T. Bukawa, H. | Int J Oral Maxillofac Surg | 2020 |
Delirium |
| Joining Forces against Delirium - From Organ-System Care to Whole-Human Care | Inouye, S. K. | N Engl J Med | 2020 |
Aged |
| Incidence of and risk factors for postoperative delirium in older adult patients undergoing noncardiac surgery: a prospective study | Iamaroon, A. Wongviriyawong, T. Sura-Arunsumrit, P. Wiwatnodom, N. Rewuri, N. Chaiwat, O. | BMC Geriatr | 2020 |
Collaborative approach |
| Delirium misdiagnosis risk in psychiatry: a machine learning-logistic regression predictive algorithm | Hercus, C. Hudaib, A. R. | BMC Health Serv Res | 2020 |
Delirium |