What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Exercise for acutely hospitalised older medical patients
- Authors
- Hartley, P. Keating, J. L. Jeffs, K. J. Raymond, M. J. Smith, T. O
- Year
- 2022
- Journal
- Cochrane Database Syst Rev
- Abstract
BACKGROUND: Approximately 30% of hospitalised older adults experience hospital-associated functional decline. Exercise interventions that promote in-hospital activity may prevent deconditioning and thereby maintain physical function during hospitalisation. This is an update of a Cochrane Review first published in 2007. OBJECTIVES: To evaluate the benefits and harms of exercise interventions for acutely hospitalised older medical inpatients on functional ability, quality of life (QoL), participant global assessment of success and adverse events compared to usual care or a sham-control intervention. SEARCH METHODS: We used standard, extensive Cochrane search methods. The latest search date was May 2021. SELECTION CRITERIA: We included randomised or quasi-randomised controlled trials evaluating an in-hospital exercise intervention in people aged 65 years or older admitted to hospital with a general medical condition. We excluded people admitted for elective reasons or surgery. DATA COLLECTION AND ANALYSIS: We used standard Cochrane methods. Our major outcomes were 1. independence with activities of daily living; 2. functional mobility; 3. new incidence of delirium during hospitalisation; 4. QoL; 5. number of falls during hospitalisation; 6. medical deterioration during hospitalisation and 7. participant global assessment of success. Our minor outcomes were 8. death during hospitalisation; 9. musculoskeletal injuries during hospitalisation; 10. hospital length of stay; 11. new institutionalisation at hospital discharge; 12. hospital readmission and 13. walking performance. We used GRADE to assess certainty of evidence for each major outcome. We categorised exercise interventions as: rehabilitation-related activities (interventions designed to increase physical activity or functional recovery, but did not follow a specified exercise protocol); structured exercise (interventions that included an exercise intervention protocol but did not include progressive resistance training); and progressive resistance exercise (interventions that included an element of progressive resistance training). MAIN RESULTS: We included 24 studies (nine rehabilitation-related activity interventions, six structured exercise interventions and nine progressive resistance exercise interventions) with 7511 participants. All studies compared exercise interventions to usual care; two studies, in addition to usual care, used sham interventions. Mean ages ranged from 73 to 88 years, and 58% of participants were women. Several studies were at high risk of bias. The most common domain assessed at high risk of bias was measurement of the outcome, and five studies (21%) were at high risk of bias arising from the randomisation process. Exercise may have no clinically important effect on independence in activities of daily living at discharge from hospital compared to controls (16 studies, 5174 participants; low-certainty evidence). Five studies used the Barthel Index (scale: 0 to 100, higher scores representing greater independence). Mean scores at discharge in the control groups ranged from 42 to 96 points, and independence in activities of daily living was 1.8 points better (0.43 worse to 4.12 better) with exercise compared to controls. The minimally clinical important difference (MCID) is estimated to be 11 points. We are uncertain regarding the effect of exercise on functional mobility at discharge from the hospital compared to controls (8 studies, 2369 participants; very low-certainty evidence). Three studies used the Short Physical Performance Battery (SPPB) (scale: 0 to 12, higher scores representing better function) to measure functional mobility. Mean scores at discharge in the control groups ranged from 3.7 to 4.9 points on the SPPB, and the estimated effect of the exercise interventions was 0.78 points better (0.02 worse to 1.57 better). A change of 1 point on the SPPB represents an MCID. We are uncertain regarding the effect of exercise on the incidence of delirium during hospitalisation compared to controls (7 trials, 2088 participants; very low-certainty evidence). The incidence of delirium during hospitalisation was 88/1091 (81 per 1000) in the control group compared with 70/997 (73 per 1000; range 47 to 114) in the exercise group (RR 0.90, 95% CI 0.58 to 1.41). Exercise interventions may result in a small clinically unimportant improvement in QoL at discharge from the hospital compared to controls (4 studies, 875 participants; low-certainty evidence). Mean QoL on the EuroQol 5 Dimensions (EQ-5D) visual analogue scale (VAS) (scale: 0 to 100, higher scores representing better QoL) ranged between 48.9 and 64.7 in the control group at discharge from the hospital, and QoL was 6.04 points better (0.9 better to 11.18 better) with exercise. A change of 10 points on the EQ-5D VAS represents an MCID. No studies measured participant global assessment of success. Exercise interventions did not affect the risk of falls during hospitalisation (moderate-certainty evidence). The incidence of falls was 31/899 (34 per 1000) in the control group compared with 31/888 (34 per 1000; range 20 to 57) in the exercise group (RR 0.99, 95% CI 0.59 to 1.65). We are uncertain regarding the effect of exercise on the incidence of medical deterioration during hospitalisation (very low-certainty evidence). The incidence of medical deterioration in the control group was 101/1417 (71 per 1000) compared with 96/1313 (73 per 1000; range 44 to 120) in the exercise group (RR 1.02, 95% CI 0.62 to 1.68). Subgroup analyses by different intervention categories and by the use of a sham intervention were not meaningfully different from the main analyses. AUTHORS’ CONCLUSIONS: Exercise may make little difference to independence in activities of daily living or QoL, but probably does not result in more falls in older medical inpatients. We are uncertain about the effect of exercise on functional mobility, incidence of delirium and medical deterioration. Certainty of evidence was limited by risk of bias and inconsistency. Future primary research on the effect of exercise on acute hospitalisation could focus on more consistent and uniform reporting of participant’s characteristics including their baseline level of functional ability, as well as exercise dose, intensity and adherence that may provide an insight into the reasons for the observed inconsistencies in findings.
- PMID
- Keywords
Aged
Aged, 80 and over
Female
Humans
Male
Activities of Daily Living
*Delirium/epidemiology
Exercise
*Quality of Life
- Page(s)
- Volume
- Issue
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| Evaluating delirium outcomes among older adults in the surgical intensive care unit | Pavone, K. J. Jablonski, J. Junker, P. Cacchione, P. Z. Compton, P. Polomano, R. C. | Heart Lung | 2020 |
Critical care |
| Association between continuous deep sedation and survival time in terminally ill cancer patients | Park, S. J. Ahn, H. K. Ahn, H. Y. Han, K. T. Hwang, I. C. | Support Care Cancer | 2020 |
Continuous deep sedation |
| Liver Transplant Patients with High Preoperative Serum Bilirubin Levels Are at Increased Risk of Postoperative Delirium: A Retrospective Study | Park, K. H. Son, H. J. Choi, Y. J. Park, G. H. Lee, Y. S. Park, J. Y. Ri, H. S. Shim, J. R. | J Clin Med | 2020 |
bilirubin |
| Smoking-cessation pharmacotherapy for patients with stroke and TIA: Systematic review | Parikh, N. S. Salehi Omran, S. Kamel, H. Elkind, M. S. V. Willey, J. Z. | J Clin Neurosci | 2020 |
Cerebrovascular Disease |
| A prospective cohort study on predictors of mortality of delirium in an emergency observational unit | Pal, S. Sharma, N. Singh, S. M. Bhutungru, S. Pannu, A. K. | QJM | 2020 |
Acute confusional state |
| Preoperative Anxiety and Depression Increases the Incidence of Delirium After Coronary Artery Bypass Graft Surgery | Pakrad, F. Pakrad, E. Darvishi, N. Poorolajal, J. | J Perianesth Nurs | 2020 |
anxiety |
| Association between fluid overload and delirium/coma in mechanically ventilated patients | Ouchi, A. Sakuramoto, H. Hoshino, H. Matsuishi, Y. Sakaguchi, T. Enomoto, Y. Hoshino, T. Shimojo, N. Inoue, Y. | Acute Med Surg | 2020 |
Brain dysfunction |
| Hallucinations after Cardiac Surgery: A Prospective Observational Study | Ottens, T. H. Sommer, I. E. C. Begemann, M. J. Schutte, M. Cramer, M. J. Suyker, W. J. Van Dijk, D. Slooter, A. J. C. | Medicina (Kaunas) | 2020 |
cardiothoracic surgery |
| Preoperative sepsis is a predictive factor for 30-day mortality after major lower limb amputation among patients with arteriosclerosis obliterans and diabetes | Otsuka, T. Arai, M. Sugimura, K. Sakai, M. Nishizawa, Y. Suzuki, Y. Okamoto, H. Kuroiwa, M. | J Orthop Sci | 2020 | |
| Patient-related and anesthesia-dependent determinants for postoperative delirium after oral and maxillofacial surgery. Results from a register-based case-control study | Ortner, F. Eberl, M. Otto, S. Wang, B. Schauberger, G. Hofmann-Kiefer, K. Saller, T. | J Stomatol Oral Maxillofac Surg | 2020 |
Dementia |
| Investigation of Free-Flap Transfer Reconstruction in Elderly Patients and Oral Intake Function | Onoda, S. Kinoshita, M. Ariyoshi, Y. | J Craniofac Surg | 2020 | |
| Delirium: a missing piece in the COVID-19 pandemic puzzle | O'Hanlon, S. Inouye, S. K. | Age Ageing | 2020 |
Covid-19 |
| Effects of Ramelteon on the Prevention of Postoperative Delirium in Older Patients Undergoing Orthopedic Surgery: The RECOVER Randomized Controlled Trial | Oh, E. S. Leoutsakos, J. M. Rosenberg, P. B. Pletnikova, A. M. Khanuja, H. S. Sterling, R. S. Oni, J. K. Sieber, F. E. Fedarko, N. S. Akhlaghi, N. Neufeld, K. J. | Am J Geriatr Psychiatry | 2020 |
Delirium |
| A roadmap to advance delirium research: Recommendations from the NIDUS Scientific Think Tank | Oh, E. S. Akeju, O. Avidan, M. S. Cunningham, C. Hayden, K. M. Jones, R. N. Khachaturian, A. S. Khan, B. A. Marcantonio, E. R. Needham, D. M. Neufeld, K. J. Rose, L. Spence, J. Tieges, Z. Vlisides, P. Inouye, S. K. | Alzheimers Dement | 2020 |
biomarkers |
| Association between a prognostic nutritional index less than 50 and the risk of medical complications after adult spinal deformity surgery | Oe, S. Yamato, Y. Hasegawa, T. Yoshida, G. Kobayashi, S. Yasuda, T. Banno, T. Arima, H. Mihara, Y. Ushirozako, H. Yamada, T. Ide, K. Watanabe, Y. Matsuyama, Y. | J Neurosurg Spine | 2020 |
ASD = adult spinal deformity |
| Communication with patients in post-traumatic confusional state: perception of rehabilitation staff | Nielsen, A. I. Power, E. Jensen, L. R. | Brain Injury | 2020 |
comprehension |
| Singapore SPICE: Sedation practices in intensive care evaluation in Singapore - A prospective cohort study of the public healthcare system | Ng, S. Y. Phua, J. Wong, Y. L. Kalyanasundaram, G. Mukhopadhyay, A. Lim, D. Chia, N. Ho, B. C. H. Bailey, M. J. Shehabi, Y. Ti, L. K. | Singapore Medical Journal | 2020 |
dexmedetomidine |
| Association of obstructive sleep apnea and postoperative cardiac complications: A systematic review and meta-analysis with trial sequential analysis | Ng, K. T. Lee, Z. X. Ang, E. Teoh, W. Y. Wang, C. Y. | J Clin Anesth | 2020 |
Cardiac complications |
| Long-term mortality in very old patients with cancer admitted to intensive care unit: A retrospective cohort study | Nassar Junior, A. P. Trevisani, M. D. S. Bettim, B. B. Caruso, P. | J Geriatr Oncol | 2020 |
Aged 80 and over |
| Functional Outcomes of Frail Patients after Cardiac Surgery: An Observational Study | Nakano, M. Nomura, Y. Suffredini, G. Bush, B. Tian, J. Yamaguchi, A. Walston, J. Hasan, R. Mandal, K. Schena, S. Hogue, C. W. Brown, C. H. | Anesthesia and Analgesia | 2020 |
adult |
| Development of a clinical score, PANDA, to predict delirium in stroke care unit | Nakamizo, T. Kanda, T. Kudo, Y. Sugawara, E. Hashimoto, E. Okazaki, A. Usuda, M. Nagai, T. Hara, H. Johkura, K. | J Neurol Sci | 2020 |
Area under curve |
| Impact of Tobacco Smoking on Outcomes after Posterior Decompression Surgery in Patients with Cervical Spondylotic Myelopathy: A Retrospective Multicenter Study | Nagoshi, N. Kono, H. Tsuji, O. Aoyama, R. Fujiyoshi, K. Shiono, Y. Ishikawa, M. Daimon, K. Hosogane, N. Takeuchi, A. Okada, E. Fujita, N. Yagi, M. Nakamura, M. Matsumoto, M. Watanabe, K. Ishii, K. Yamane, J. | Clinical Spine Surgery | 2020 |
adult |
| Role of omega-3 fatty acids in the prevention of delirium in mechanically ventilated patients | Naghibi, T. Shafigh, N. Mazloomzadeh, S. | Journal of Research in Medical Sciences | 2020 |
IRCT2015095536N5 |
| Brain BOLD MRI O(2) and CO(2) stress testing: implications for perioperative neurocognitive disorder following surgery | Mutch, W. A. C. El-Gabalawy, R. Ryner, L. Puig, J. Essig, M. Kilborn, K. Fidler, K. Graham, M. R. | Crit Care | 2020 |
Anesthesia |
| Off-label use of quetiapine in nursing homes: Does medical specialty of prescribing physicians play a role? | Müller, L. Noseda, R. Bertoli, R. Bissig, M. Ceschi, A. | British Journal of Clinical Pharmacology | 2020 |
quetiapine |
| Multidisciplinary quality improvement programme for older patients admitted to a vascular surgery ward() | Mudge, A. M. McRae, P. Donovan, P. J. Reade, M. C. | Intern Med J | 2020 |
delirium |
| Cross-cultural adaptation and validation of the 3D-CAM Chinese version in surgical ICU patients | Mu, D. L. Ding, P. P. Zhou, S. Z. Liu, M. J. Sun, X. Y. Li, X. Y. Wang, D. X. | BMC Psychiatry | 2020 |
3d-cam |
| Thiamine for Prevention of Postoperative Delirium in Patients Undergoing Gastrointestinal Surgery: A Randomized Clinical Trial | Moslemi, R. Khalili, H. Mohammadi, M. Mehrabi, Z. Mohebbi, N. | J Res Pharm Pract | 2020 |
Delirium |
| How successful are we in relieving terminal dyspnea in cancer patients? A real-world multicenter prospective observational study | Mori, M. Morita, T. Matsuda, Y. Yamada, H. Kaneishi, K. Matsumoto, Y. Matsuo, N. Odagiri, T. Aruga, E. Watanabe, H. Tatara, R. Sakurai, H. Kimura, A. Katayama, H. Suga, A. Nishi, T. Shirado, A. N. Watanabe, T. Kuchiba, A. Yamaguchi, T. Iwase, S. | Supportive Care in Cancer | 2020 | |
| Understanding Factors Associated With Psychomotor Subtypes of Delirium in Older Inpatients With Dementia | Morandi, A. Zambon, A. Di Santo, S. G. Mazzone, A. Cherubini, A. Mossello, E. Bo, M. Marengoni, A. Bellelli, G. | Journal of the American Medical Directors Association | 2020 |
intravenous catheter |
| Infection in older adults: a qualitative study of patient experience | Moore, A. McKelvie, S. Glogowska, M. Lasserson, D. Hayward, G. | Br J Gen Pract | 2020 |
aged |
| Aripiprazole for prevention of delirium in the neurosurgical intensive care unit: a double-blind, randomized, placebo-controlled study | Mokhtari, M. Farasatinasab, M. Jafarpour Machian, M. Yaseri, M. Ghorbani, M. Ramak Hashemi, S. M. Nikoobakht, M. Golchin, N. Mohammadi, G. Sistanizad, M. | Eur J Clin Pharmacol | 2020 |
Aripiprazole |
| Potentially Inappropriate Medications in a Psychogeriatric Inpatient Ward: An Audit Based on Beers Criteria | Moebs, I. Abeln, E. Siefert, A. Barak, Y. | Neurology and Therapy | 2020 |
adult |
| An 11-year review of hip fracture hospitalisations, health outcomes, and predictors of access to in-hospital rehabilitation for adults ≥ 65 years living with and without dementia: a population-based cohort study | Mitchell, R. Draper, B. Brodaty, H. Close, J. Ting, H. P. Lystad, R. Harris, I. Harvey, L. Sherrington, C. Cameron, I. D. Braithwaite, J. | Osteoporos Int | 2020 |
Aged care |
| Evaluation of a co-produced delirium awareness programme for undergraduate nursing students in Northern Ireland: a pre-test/post-test study | Mitchell, G. McVeigh, C. Carlisle, S. Brown-Wilson, C. | BMC Nurs | 2020 |
Co-design |
| Perioperative dexmedetomidine and postoperative delirium in non-cardiac surgery: a meta-analysis | Ming, S. Zhang, X. Gong, Z. Xie, Y. Xie, Y. | Ann Palliat Med | 2020 |
Dexmedetomidine |
| Cholinesterases and Anticholinergic Medications in Postoperative Pediatric Delirium | Meyburg, J. Ritsert, M. L. Traube, C. Plaschke, K. von Haken, R. | Pediatr Crit Care Med | 2020 | |
| Comparison of novel tools with traditional cognitive tests in detecting delirium in elderly medical patients | Meagher, D. J. O'Connell, H. Leonard, M. Williams, O. Awan, F. Exton, C. Tenorio, M. O'Connor, M. Dunne, C. P. Cullen, W. McFarland, J. Adamis, D. | World J Psychiatry | 2020 |
Assessment |
| A systematic review and meta-analysis of the accuracy of the clock drawing test (CDT) in the identification of delirium in older hospitalised patients | Meagher, D. Williams, O. A. O'Connell, H. Leonard, M. Cullen, W. Dunne, C. P. Mulligan, O. Adamis, D. | Aging & mental health | 2020 |
adult |
| Family intervention improves outcomes for patients with delirium: Systematic review and meta-analysis | McKenzie, J. Joy, A. | Australas J Ageing | 2020 |
caregivers |
| Effectiveness and Safety of Intrathecal Ziconotide: Final Results of the Patient Registry of Intrathecal Ziconotide Management (PRIZM) | McDowell, G. C. Saulino, M. F. Wallace, M. Grigsby, E. J. Rauck, R. L. Kim, P. Vanhove, G. F. Ryan, R. Huang, I. Z. Deer, T. | Pain medicine (Malden, Mass.) | 2020 |
adult |
| Management Effort for Delirium and Insomnia in Patients with Acute Ischemic Stroke (MEDIAS) Study | Matsuzono, K. Mashiko, T. Ozawa, T. Miura, K. Suzuki, M. Furuya, K. Ozawa, M. Anan, Y. Shimazaki, H. Koide, R. Tanaka, R. Fujimoto, S. | Psychiatry Clin Neurosci | 2020 | |
| High Prevalence of Oropharyngeal Dysphagia in Acutely Hospitalized Patients Aged 80 Years and Older | Mateos-Nozal, J. Montero-Errasquín, B. Sánchez García, E. Romero Rodríguez, E. Cruz-Jentoft, A. J. | J Am Med Dir Assoc | 2020 |
Dysphagia |
| Dexmedetomidine in medical cardiac intensive care units. Data from a multicenter prospective registry | Mateos Gaitan, R. Vicent, L. Rodriguez-Queralto, O. Lopez-de-Sa, E. Elorriaga, A. Pastor, G. Bañeras, J. Lorenzo, B. García-Rubira, J. C. Corbi, M. Ariza, A. Martínez-Sellés, M. | Int J Cardiol | 2020 |
Adverse effects |
| Myocardial Function in Patients With Radiation-Associated Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement: A Layer-Specific Strain Analysis Study | Martinez, C. Cicenia, M. Sprynger, M. Postolache, A. Ilardi, F. Dulgheru, R. Radermecker, M. Esposito, G. Marechal, P. Marechal, V. Donis, N. Tridetti, J. Nguyen Trung, M. L. Sugimoto, T. Tsugu, T. Go, Y. Y. Coisne, A. Montaigne, D. Fattouch, K. Nchimi, A | JACC: Cardiovascular Imaging | 2020 |
CoreValve self-expandable biologic prosthesis |
| Prevalence and clinical correlates of non-convulsive status epilepticus in elderly patients with acute confusional state: A systematic literature review | Manfredonia, F. Saturno, E. Lawley, A. Gasverde, S. Cavanna, A. E. | J Neurol Sci | 2020 |
Acute confusional state |
| Downstream consequences of abnormal cognitive screening in older adults seen pretreatment in a geriatric oncology clinic | Malik, U. Alam, Z. Loucks, A. Jin, R. Yokom, D. Watt, S. Berger, A. Romanovsky, L. Puts, M. Alibhai, S. M. H. | J Geriatr Oncol | 2020 |
Cognitive impairment |
| A Study of the Psychometric Properties of the "Stanford Proxy Test for Delirium" (S-PTD): A New Screening Tool for the Detection of Delirium | Maldonado, J. R. Sher, Y. I. Benitez-Lopez, M. A. Savant, V. Garcia, R. Ament, A. De Guzman, E. | Psychosomatics | 2020 |
S-ptd |
| Family Identification of Delirium in the Emergency Department in Patients With and Without Dementia: Validity of the Family Confusion Assessment Method (FAM-CAM) | Mailhot, T. Darling, C. Ela, J. Malyuta, Y. Inouye, S. K. Saczynski, J. | J Am Geriatr Soc | 2020 |
Fam-cam |
| Frailty Is Associated With Postoperative Delirium But Not With Postoperative Cognitive Decline in Older Noncardiac Surgery Patients | Mahanna-Gabrielli, E. Zhang, K. Sieber, F. E. Lin, H. M. Liu, X. Sewell, M. Deiner, S. G. Boockvar, K. S. | Anesth Analg | 2020 |
Aged |
| 2019-NCoV: What every neurologist should know? | Mahajan, N. Singla, M. Singh, B. Sajja, V. Bansal, P. Paul, B. Goel, P. Midha, R. Bansal, R. Singh, G. | Annals of Indian Academy of Neurology | 2020 |
alanine aminotransferase |
| Age, Comorbidities and Fear of Fall: mortality predictors associated with fall-related fractures | Magdalini, V. Petros, I. Constantinos, T. Garyfalia, S. P. Emmanouil, P. Christos, K. George, K. Kalliopi, A. George, S. Symeon, H. P. | Maedica (Buchar) | 2020 | |
| Stress-Induced Behavioral Quiescence and Abnormal Rest-Activity Rhythms During Critical Illness | Maas, M. B. Lizza, B. D. Kim, M. Abbott, S. M. Gendy, M. Reid, K. J. Zee, P. C. | Crit Care Med | 2020 | |
| Incidence and risk factors of delirium in icu patients | Ma, W. Zheng, J. Xu, S. Huo, Z. | International Journal of Clinical and Experimental Medicine | 2020 |
stomach tube |
| Age, preoperative higher serum cortisol levels, and lower serum acetylcholine levels predict delirium after percutaneous coronary intervention in acute coronary syndrome patients accompanied with renal dysfunction | Ma, J. Fan, M. Wang, Z. | Indian Journal of Psychiatry | 2020 |
IE33 |
| Non-Pharmacologic Multicomponent Interventions Preventing Delirium in Hospitalized People | Ludolph, P. Stoffers-Winterling, J. Kunzler, A. M. Rösch, R. Geschke, K. Vahl, C. F. Lieb, K. | J Am Geriatr Soc | 2020 |
delirium |
| Usefulness of postoperative serum translocator protein as a predictive marker for delirium after breast cancer surgery in elderly women | Lu, G. W. Chou, Y. E. Jin, W. L. Su, X. B. | J Int Med Res | 2020 |
Translocator protein |
| Characteristics, Symptom Management, and Outcomes of 101 Patients With COVID-19 Referred for Hospital Palliative Care | Lovell, N. Maddocks, M. Etkind, S. N. Taylor, K. Carey, I. Vora, V. Marsh, L. Higginson, I. J. Prentice, W. Edmonds, P. Sleeman, K. E. | J Pain Symptom Manage | 2020 |
Covid-19 |
| Characterisation of ICU sleep by a commercially available activity tracker and its agreement with patient-perceived sleep quality | Louzon, P. Andrews, J. Torres, X. Pyles, E. Ali, M. Du, Y. Devlin, J. | BMJ Open Respir Res | 2020 |
equipment evaluations |
| Surgical treatment of hip fracture in centenarians: Complications and independent risk factors of death | López, Torres, II Sanz-Ruiz, P. Montero-Fernández, N. Chana, F. Serra-Rexach, J. A. Benjumea-Carrasco, A. Vaquero-Martín, J. | Injury | 2020 |
Centenarians |
| Long-term survival of femoral neck fracture patients aged over ninety years: Arthroplasty compared with nonoperative treatment | Liu, Y. Zhang, C. W. Zhao, X. D. | BMC Musculoskeletal Disorders | 2020 |
albumin |
| Subjective memory complaints predict poorer functional recovery during the first year following hip-fracture surgery among elderly adults | Liu, H. Y. Wang, H. P. Chen, C. Y. Wu, C. C. Hua, M. S. Lin, Y. E. Lin, Y. C. Shyu, Y. L. | Int J Geriatr Psychiatry | 2020 |
hip fracture |
| Delirium Severity Trajectories and Outcomes in ICU Patients: Defining a Dynamic Symptom Phenotype | Lindroth, H. Khan, B. A. Carpenter, J. S. Gao, S. Perkins, A. J. Khan, S. H. Wang, S. Jones, R. N. Boustani, M. A. | Ann Am Thorac Soc | 2020 | |
| Early mobilisation of ventilated patients in the intensive care unit: A survey of critical care clinicians in an Australian tertiary hospital | Lin, F. Phelan, S. Chaboyer, W. Mitchell, M. | Aust Crit Care | 2020 |
Attitudes |
| Perioperative Dexmedetomidine Supplement Decreases Delirium Incidence After Adult Cardiac Surgery: A Randomized, Double-Blind, Controlled Study | Likhvantsev, V. V. Landoni, G. Grebenchikov, O. A. Ovezov, A. M. Skripkin, Y. V. Lembo, R. Gaevskiy, D. I. Tereshina, A. A. Yavorovskiy, A. G. | Journal of Cardiothoracic and Vascular Anesthesia | 2020 |
adult |
| Derivation and Validation of a Risk Stratification System for Predicting Postoperative Cognitive Impairment | Liao, Y. Su, X. Ouyang, W. Li, L. Chen, S. Chou, J. Le, Y. | J Invest Surg | 2020 |
Postoperative cognitive dysfunction |
| Effects of anesthesia depth on postoperative cognitive function and inflammation: a systematic review and meta-analysis | Li, Y. Zhang, B. | Minerva Anestesiol | 2020 | |
| Prevalence, outcome and prognostic factors of neuropsychiatric systemic lupus erythematosus: A real world single center study | Li, X. Xiang, X. Sun, J. Liu, S. Liu, Y. Feng, L. Li, C. Li, Z. | Mod Rheumatol | 2020 |
Neuropsychiatric systemic lupus erythematosus |
| Postoperative Delirium Following Joint Replacement in Patients With Dementia in New South Wales, Australia: A State-Wide Retrospective Cohort Study | Li, X. Du, W. Parkinson, A. Glasgow, N. | Research in gerontological nursing | 2020 |
adult |
| Effect of dexmedetomidine on prevention of postoperative nausea and vomiting in pediatric strabismus surgery: a randomized controlled study | Li, S. Liu, T. Xia, J. Jia, J. Li, W. | BMC Ophthalmol | 2020 |
Dexmedetomidine |
| Toxicity and survival outcomes of autologous stem cell transplant in multiple myeloma patients with renal insufficiency: an institutional comparison between two eras | Li, A. Y. Atenafu, E. G. Bernard, R. S. Masih-Khan, E. Reece, D. Franke, N. Tiedemann, R. Prica, A. Trudel, S. Kukreti, V. Chen, C. I. | Bone Marrow Transplant | 2020 | |
| Risk Prediction for Adverse Outcomes for Frail Older Persons with Complex Healthcare and Social Care Needs Admitted to a Community Virtual Ward Model | Lewis, C. O'Caoimh, R. Patton, D. O'Connor, T. Moore, Z. Nugent, L. E. | Clin Interv Aging | 2020 |
case management |
| The role of melatonin and melatonin receptor agonist in the prevention of sleep disturbances and delirium in intensive care unit - a clinical review | Lewandowska, K. Małkiewicz, M. A. Siemiński, M. Cubała, W. J. Winklewski, P. J. Mędrzycka-Dąbrowska, W. A. | Sleep Med | 2020 |
Delirium |
| Neurological manifestations associated with COVID-19: a review and a call for action | Leonardi, M. Padovani, A. McArthur, J. C. | Journal of Neurology | 2020 |
acroparesthesia |
| "You've got to keep moving, keep going": Understanding older patients' experiences and perceptions of delirium and nonpharmacological delirium prevention strategies in the acute hospital setting | Lee-Steere, K. Liddle, J. Mudge, A. Bennett, S. McRae, P. Barrimore, S. E. | J Clin Nurs | 2020 |
adult |
| The effect of dexmedetomidine on postoperative behaviour change in children: a randomised controlled trial | Lee-Archer, P. F. von Ungern-Sternberg, B. S. Reade, M. Betts, M. Haenke, D. Keys, A. Rance, T. Gibbons, K. Long, D. | Anaesthesia | 2020 |
behaviour changes |
| Developing delirium best practice: a systematic review of education interventions for healthcare professionals working in inpatient settings | Lee, S. Y. Fisher, J. Wand, A. P. F. Milisen, K. Detroyer, E. Sockalingam, S. Agar, M. Hosie, A. Teodorczuk, A. | European Geriatric Medicine | 2020 |
behavior change |
| Outcomes of the Extreme Elderly Undergoing Anaesthesia and Surgery amongst Southeast Asians | Lee, S. J. Ng, O. Thong, S. Y. | Anesthesiology Research and Practice | 2020 |
dynamic hip screw |
| Predictors of New-Onset Physical Restraint Use in Critically Ill Adults | Lawson, T. N. Tan, A. Thrane, S. E. Happ, M. B. Mion, L. C. Tate, J. Balas, M. C. | Am J Crit Care | 2020 | |
| Decision-making for older patients undergoing emergency laparotomy: defining patient and clinician values and priorities | Law, J. Welch, C. Javanmard-Emamghissi, H. Clark, M. Bisset, C. N. O'Neil, P. Moug, S. J. | Colorectal Dis | 2020 |
Emergency laparotomy |
| Delirium prevalence and prevention in patients with acute brain injury: A prospective before-and-after intervention study | Larsen, L. K. Møller, K. Petersen, M. Egerod, I. | Intensive & critical care nursing | 2020 |
adult |
| Comparison of Hydromorphone versus Fentanyl-based Sedation in Extracorporeal Membrane Oxygenation: A Propensity-Matched Analysis | Landolf, K. M. Rivosecchi, R. M. Goméz, H. Sciortino, C. M. Murray, H. N. Padmanabhan, R. R. Sanchez, P. G. Harano, T. Sappington, P. L. | Pharmacotherapy | 2020 |
acute respiratory distress syndrome |
| Collaborative Delirium Prevention in the Age of COVID-19 | LaHue, S. C. James, T. C. Newman, J. C. Esmaili, A. M. Ormseth, C. H. Ely, E. W. | J Am Geriatr Soc | 2020 |
Aged |
| Intra-operative hyperoxia and the risk of delirium in elderly patients after cardiac surgery | Kupiec, A. Adamik, B. Forkasiewicz-Gardynik, K. Goździk, W. | Aging (Albany NY) | 2020 |
cardiac surgery |
| Clinical profile and predictor of adverse outcome in children with acute encephalitis syndrome: A cross-sectional study | Kuntal, M. Swarnkar, K. | Journal of Krishna Institute of Medical Sciences University | 2020 |
immunoglobulin M |
| Intraoperative Optimization of Both Depth of Anesthesia and Cerebral Oxygenation in Elderly Patients Undergoing Coronary Artery Bypass Graft Surgery-A Randomized Controlled Pilot Trial | Kunst, G. Gauge, N. Salaunkey, K. Spazzapan, M. Amoako, D. Ferreira, N. Green, D. W. Ballard, C. | J Cardiothorac Vasc Anesth | 2020 |
cardiac anesthesia |
| Establishment of an enhanced recovery after surgery protocol in minimally invasive heart valve surgery | Kubitz, J. C. Schulte-Uentrop, L. Zoellner, C. Lemke, M. Messner-Schmitt, A. Kalbacher, D. Sill, B. Reichenspurner, H. Koell, B. Girdauskas, E. | PLoS One | 2020 | |
| Preoperative cognitive impairment associated with oversedation during recovery from anesthesia | Kruthiventi, S. C. Laporta, M. L. Deljou, A. Knopman, D. S. Petersen, R. C. Schroeder, D. R. Sprung, J. Weingarten, T. N. | J Anesth | 2020 |
Anesthesia |
| Non-contact monitoring of agitation and use of a sheltering device in patients with dementia in emergency departments: a feasibility study | Kroll, L. Böhning, N. Müßigbrodt, H. Stahl, M. Halkin, P. Liehr, B. Grunow, C. Kujumdshieva-Böhning, B. Freise, C. Hopfenmüller, W. Friesdorf, W. Jockers-Scherübl, M. Somasundaram, R. | BMC Psychiatry | 2020 |
Dementia, agitation |
| COVID-19: ICU delirium management during SARS-CoV-2 pandemic | Kotfis, K. Williams Roberson, S. Wilson, J. E. Dabrowski, W. Pun, B. T. Ely, E. W. | Crit Care | 2020 |
Betacoronavirus |
| COVID-19: What do we need to know about ICU delirium during the SARS-CoV-2 pandemic? | Kotfis, K. Williams Roberson, S. Wilson, J. Pun, B. Ely, E. W. Jeżowska, I. Jezierska, M. Dabrowski, W. | Anaesthesiol Intensive Ther | 2020 |
Pics |
| The impact of acute kidney injury in the perioperative period on the incidence of postoperative delirium in patients undergoing coronary artery bypass grafting—observational cohort study | Kotfis, K. Ślozowska, J. Listewnik, M. Szylińska, A. Rotter, I. | International Journal of Environmental Research and Public Health | 2020 |
creatinine |
| Association between Preoperative Obstructive Sleep Apnea and Preoperative Positive Airway Pressure with Postoperative Intensive Care Unit Delirium | King, C. R. Fritz, B. A. Escallier, K. Ju, Y. E. S. Lin, N. McKinnon, S. Avidan, M. S. Palanca, B. J. | JAMA Network Open | 2020 |
adult |
| Risk factors and outcomes of sepsis-associated delirium in intensive care unit patients: A secondary data analysis | Kim, Y. Jin, Y. Jin, T. Lee, S. M. | Intensive Crit Care Nurs | 2020 |
Delirium |
| Factors affecting the post-anesthetic recovery score and length of stay in the recovery room in elderly patients with hypertension | Kim, S. Kwon, M. | Medico-Legal Update | 2020 |
aged |
| Comparative efficacy and acceptability of pharmacological interventions for the treatment and prevention of delirium: A systematic review and network meta-analysis | Kim, M. S. Rhim, H. C. Park, A. Kim, H. Han, K. M. Patkar, A. A. Pae, C. U. Han, C. | J Psychiatr Res | 2020 |
Antipsychotics |
| Pre-operative hemoglobin level and use of sedative-hypnotics are independent risk factors for post-operative delirium following total knee arthroplasty | Kijima, E. Kayama, T. Saito, M. Kurosaka, D. Ikeda, R. Hayashi, H. Kubota, D. Hyakutake, T. Marumo, K. | BMC Musculoskelet Disord | 2020 |
Anemia |
| Decreasing Delirium Through Music: A Randomized Pilot Trial | Khan, S. H. Xu, C. Purpura, R. Durrani, S. Lindroth, H. Wang, S. Gao, S. Heiderscheit, A. Chlan, L. Boustani, M. Khan, B. A. | Am J Crit Care | 2020 | |
| Time trends of delirium rates in the intensive care unit | Khan, S. H. Lindroth, H. Hendrie, K. Wang, S. Imran, S. Perkins, A. J. Gao, S. Vahidy, F. S. Boustani, M. Khan, B. A. | Heart Lung | 2020 |
Delirium |
| Neurological complications in recipients after living donor liver transplantation | Khalil, M. Elbanhawy, I. Elsherbiny, A. Amer, H. Ahmed, S. | Neurology India | 2020 |
ammonia |