What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Preventing Postoperative Delirium After Major Noncardiac Thoracic Surgery-A Randomized Clinical Trial.
- Authors
- Khan, B. A. Perkins, A. J. Campbell, N. L. Gao, S. Khan, S. H. Wang, S. Fuchita, M. Weber, D. J. Zarzaur, B. L. Boustani, M. A. Kesler, K.
- Year
- 2018
- Journal
- J Am Geriatr Soc
- Abstract
OBJECTIVES: To assess the efficacy of haloperidol in reducing postoperative delirium in individuals undergoing thoracic surgery. DESIGN: Randomized double-blind placebo-controlled trial. SETTING: Surgical intensive care unit (ICU) of tertiary care center. PARTICIPANTS: Individuals undergoing thoracic surgery (N=135). INTERVENTION: Low-dose intravenous haloperidol (0.5 mg three times daily for a total of 11 doses) administered postoperatively. MEASUREMENTS: The primary outcome was delirium incidence during hospitalization. Secondary outcomes were time to delirium, delirium duration, delirium severity, and ICU and hospital length of stay. Delirium was assessed using the Confusion Assessment Method for the ICU and delirium severity using the Delirium Rating Scale-Revised. RESULTS: Sixty-eight participants were randomized to receive haloperidol and 67 placebo. No significant differences were observed between those receiving haloperidol and those receiving placebo in incident delirium (n=15 (22.1%) vs n=19 (28.4%); p = .43), time to delirium (p = .43), delirium duration (median 1 day, interquartile range (IQR) 1-2 days vs median 1 day, IQR 1-2 days; p = .71), delirium severity, ICU length of stay (median 2.2 days, IQR 1-3.3 days vs median 2.3 days, IQR 1-4 days; p = .29), or hospital length of stay (median 10 days, IQR 8-11.5 days vs median 10 days, IQR 8-12 days; p = .41). In the esophagectomy subgroup (n = 84), the haloperidol group was less likely to experience incident delirium (n=10 (23.8%) vs n=17 (40.5%); p = .16). There were no differences in time to delirium (p = .14), delirium duration (median 1 day, IQR 1-2 days vs median 1 day, IQR 1-2 days; p = .71), delirium severity, or hospital length of stay (median 11 days, IQR 10-12 days vs median days 11, IQR 10-15 days; p = .26). ICU length of stay was significantly shorter in the haloperidol group (median 2.8 days, IQR 1.1-3.8 days vs median 3.1 days, IQR 2.1-5.1 days; p = .03). Safety events were comparable between the groups. CONCLUSION: Low-dose postoperative haloperidol did not reduce delirium in individuals undergoing thoracic surgery but may be efficacious in those undergoing esophagectomy. J Am Geriatr Soc 66:2289-2297, 2018.
- PMID
- Keywords
Icu
cognition
delirium
esophagectomy
haloperidol
- Page(s)
- 2289-97
- Volume
- 66
- Issue
- 12
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| Cohort study into the neural correlates of postoperative delirium: the role of connectivity and slow-wave activity | Tanabe, S. Mohanty, R. Lindroth, H. Casey, C. Ballweg, T. Farahbakhsh, Z. Krause, B. Prabhakaran, V. Banks, M. I. Sanders, R. D. | Br J Anaesth | 2020 |
cognitive dysfunction |
| Preoperative circadian physical activity rhythm and postoperative delirium in cardiovascular surgery patients | Tan, C. Saito, N. Miyawaki, I. Shiotani, H. | Chronobiol Int | 2020 |
Postoperative delirium |
| Real-world evidence of the safety and efficacy profile of suvorexant in elderly patients with insomnia: a sub-analysis of the post-marketing drug-use results survey in Japan | Takeuchi, Y. Sano, H. Asai, Y. Miyazaki, M. Iwakura, M. Maeda, Y. | Current Medical Research and Opinion | 2020 |
hypnotic agent |
| Electroencephalography-Guided Anesthetic Delivery for Preventing Postoperative Delirium in Adults: An Updated Meta-analysis | Sun, Y. Ye, F. Wang, J. Ai, P. Wei, C. Wu, A. Xie, W. | Anesth Analg | 2020 | |
| Risk and Consequences of Postoperative Delirium in Cardiac Surgery | Sugimura, Y. Sipahi, N. F. Mehdiani, A. Petrov, G. Awe, M. Minol, J. P. Boeken, U. Korbmacher, B. Lichtenberg, A. Dalyanoglu, H. | Thorac Cardiovasc Surg | 2020 | |
| Risk of Hospitalized Falls and Hip Fractures in 22,103 Older Adults Receiving Mental Health Care vs 161,603 Controls: A Large Cohort Study | Stubbs, B. Perara, G. Koyanagi, A. Veronese, N. Vancampfort, D. Firth, J. Sheehan, K. De Hert, M. Stewart, R. Mueller, C. | J Am Med Dir Assoc | 2020 |
Hip fracture |
| Pharmacist-driven discontinuation of antipsychotics for ICU delirium: A quasi-experimental study | Stuart, M. M. Smith, Z. R. Payter, K. A. Martz, C. R. To, L. Swiderek, J. L. Coba, V. E. Peters, M. A. | JACCP Journal of the American College of Clinical Pharmacy | 2020 |
adult |
| Interventions to prevent in-hospital falls in older people with cognitive impairment for further research: a mixed studies review | Stockwell-Smith, G. Adeleye, A. Chaboyer, W. Cooke, M. Phelan, M. Todd, J. A. Grealish, L. | J Clin Nurs | 2020 |
In-hospital fall |
| Early Identification of Delirium in Intensive Care Unit Patients: Improving the Quality of Care | Spiegelberg, J. Song, H. Pun, B. Webb, P. Boehm, L. M. | Crit Care Nurse | 2020 | |
| Efficacy and Safety of Dexmedetomidine for Prolonged Sedation in the PICU: A Prospective Multicenter Study (PROSDEX) | Sperotto, F. Mondardini, M. C. Dell'Oste, C. Vitale, F. Ferrario, S. Lapi, M. Ferrero, F. Dusio, M. P. Rossetti, E. Daverio, M. Amigoni, A. | Pediatr Crit Care Med | 2020 | |
| Restricted versus liberal intraoperative benzodiazepine use in cardiac anaesthesia for reducing delirium (B-Free Pilot): a pilot, multicentre, randomised, cluster crossover trial | Spence, J. Belley-Côté, E. Jacobsohn, E. Lee, S. F. Whitlock, R. Bangdiwala, S. Syed, S. Sarkaria, A. MacIsaac, S. Lengyel, A. Long, S. Um, K. McIntyre, W. F. Kavosh, M. Fast, I. Arora, R. Lamy, A. Connolly, S. Devereaux, P. J. | Br J Anaesth | 2020 |
awareness |
| Thoracic continuous spinal anesthesia for high-risk comorbid older patients undergoing major abdominal surgery: one-year experience of an Italian geriatric hospital | Spannella, F. Giulietti, F. Damiani, E. Faloia, L. Stronati, M. Venezia, A. Vincenzi, P. Castellani, D. Boccoli, G. Dellabella, M. Giampieri, M. Sarzani, R. Starnari, R. | Minerva Anestesiol | 2020 | |
| Identification of distinct clinical phenotypes in mechanically ventilated patients with acute brain dysfunction using cluster analysis | Souza-Dantas, V. C. Dal-Pizzol, F. Tomasi, C. D. Spector, N. Soares, M. Bozza, F. A. Póvoa, P. Salluh, J. I. F. | Medicine (Baltimore) | 2020 |
Apache |
| Validation of a multidisciplinary care protocol for critically ill patients with delirium | Souza, T. L. Azzolin, K. O. Souza, E. N. | Revista gaucha de enfermagem | 2020 |
adult |
| Hospital Costs and Reimbursement Model for a Geriatric Emergency Department | Southerland, L. T. Savage, E. L. Muska Duff, K. Caterino, J. M. Bergados, T. R. Hunold, K. M. Finnegan, G. I. Archual, G. | Acad Emerg Med | 2020 | |
| Natural light exposure and delirium in ICU: does the dark side cloud everything? | Sonneville, R. Smonig, R. Dupuis, C. Bouadma, L. de Montmollin, E. Timsit, J. F. | Annals of Intensive Care | 2020 |
sedative agent |
| Neurocognitive Complications after Ventricular Neuroendoscopy: A Systematic Review | Soleman, J. Guzman, R. | Behavioural Neurology | 2020 |
rigid endoscope |
| Investigation of ward fidelity to a multicomponent delirium prevention intervention during a multicentre, pragmatic, cluster randomised, controlled feasibility trial | Smith, J. Green, J. Siddiqi, N. Inouye, S. K. Collinson, M. Farrin, A. Young, J. | Age Ageing | 2020 |
delirium prevention |
| Clinical outcomes associated with sedation and analgesia in patients supported with venoarterial extracorporeal membrane oxygenation | Skelton, P. A. Lillyblad, M. P. Eckman, P. M. Samara, M. A. Williams, D. M. Wilson, K. J. Stanberry, L. I. Hryniewicz, K. M. | Int J Artif Organs | 2020 |
Extracorporeal membrane oxygenation |
| Are Antipsychotics Helpful for Preventing or Treating Delirium? | Singu, S. Koneru, M. Robinson, K. A. Neufeld, K. J. Oh, E. S. Wilson, L. M. Needham, D. M. Balagani, A. Aldabain, L. Nikooie, R. Fick, D. M. | J Gerontol Nurs | 2020 | |
| Family caregiver's experience of caring for an older adult with delirium: A systematic review | Shrestha, P. Fick, D. M. | Int J Older People Nurs | 2020 |
delirium |
| Dexmedetomidine in the prevention of postoperative delirium in elderly patients following non-cardiac surgery: A systematic review and meta-analysis | Shen, Q. H. Li, H. F. Zhou, X. Y. Yuan, X. Z. | Clin Exp Pharmacol Physiol | 2020 |
dexmedetomidine |
| Relation of serum melatonin levels to postoperative delirium in older patients undergoing major abdominal surgery | Shen, Q. H. Li, H. F. Zhou, X. Y. Lu, Y. P. Yuan, X. Z. | J Int Med Res | 2020 |
Postoperative delirium |
| Characteristics and Outcomes of Dementia Patients Who Receive Inpatient Palliative Care Consultation | Sharda, N. Zietlow, K. Wong, S. Kuchibhatla, M. Johnson, K. S. | J Am Geriatr Soc | 2020 |
dementia |
| Low Frontal Alpha Power Is Associated With the Propensity for Burst Suppression: An Electroencephalogram Phenotype for a "Vulnerable Brain" | Shao, Y. R. Kahali, P. Houle, T. T. Deng, H. Colvin, C. Dickerson, B. C. Brown, E. N. Purdon, P. L. | Anesth Analg | 2020 | |
| Dynamics of cerebral oxygenation during rapid ventricular pacing and its impact on outcome in transfemoral transcatheter aortic valve implantation | Seppelt, P. C. Mas-Peiro, S. De Rosa, R. Murray, I. M. Arsalan, M. Holzer, L. Lotz, G. Meybohm, P. Zacharowski, K. Walther, T. Zeiher, A. M. Fichtlscherer, S. Vasa-Nicotera, M. | Catheter Cardiovasc Interv | 2020 |
Nirs |
| Haemodynamic changes and emergence delirium in children undergoing isoflurane general anaesthesia for dental treatments: effect of propofol administration | Selvi-Kuvvetli, S. Turan, B. S. Bayrak, G. D. Noyan, A. | Pediatric Dental Journal | 2020 |
propofol |
| Anxiety symptoms are quantitatively and qualitatively different in dementia with Lewy bodies than in Alzheimer's disease in the years preceding clinical diagnosis | Segers, K. Benoit, F. Meyts, J. M. Surquin, M. | Psychogeriatrics | 2020 |
Alzheimerʼs disease |
| Evaluation of Sedation Outcomes Following Increased Dexmedetomidine Use in the ICU | Schuler, B. R. Kovacevic, M. P. Dube, K. M. Szumita, P. M. DeGrado, J. R. | Crit Care Explor | 2020 |
benzodiazepines |
| Effect of Flumazenil on Hypoactive Delirium in the ICU: A Double-Blind, Placebo-Controlled Pilot Study | Schomer, K. J. Duby, J. J. Firestone, R. L. Louie, E. L. Sebat, C. M. Love, D. M. Cocanour, C. S. Albertson, T. E. | Crit Care Explor | 2020 |
benzodiazepine |
| Neuropsychiatric adverse events of chloroquine: a real-world pharmacovigilance study using the FDA Adverse Event Reporting System (FAERS) database | Sato, K. Mano, T. Iwata, A. Toda, T. | Biosci Trends | 2020 |
Adverse Drug Reaction Reporting Systems |
| Prospective Study of Factors Associated With Postoperative Delirium After Urgent Abdominal Surgery | Sánchez Acedo, P. Eguaras Córdoba, I. Zazpe Ripa, C. Herrera Cabezón, J. Tarifa Castilla, A. | Cir Esp | 2020 |
Ancianos |
| Prospective Study of Factors Associated With Postoperative Delirium After Urgent Abdominal Surgery | Sánchez Acedo, P. Eguaras Córdoba, I. Zazpe Ripa, C. Herrera Cabezón, J. Tarifa Castilla, A. | Cir Esp | 2020 |
Ancianos |
| Non-pharmacological approaches in the prevention of delirium | Salvi, F. Young, J. Lucarelli, M. Aquilano, A. Luzi, R. Dell’Aquila, G. Cherubini, A. | European Geriatric Medicine | 2020 |
psychotropic agent |
| Natriuretic Peptides as a Prognostic Marker for Delirium in Cardiac Surgery-A Pilot Study | Saller, T. Peterss, S. Scheiermann, P. Eser-Valeri, D. Ehler, J. Bruegger, D. Chappell, D. Kofler, O. Hagl, C. Hofmann-Kiefer, K. | Medicina (Kaunas) | 2020 |
biomarker |
| Prospective Evaluation of Delirium in Geriatric Patients Undergoing Emergency General Surgery | Saljuqi, A. T. Hanna, K. Asmar, S. Tang, A. Zeeshan, M. Gries, L. Ditillo, M. Kulvatunyou, N. Castanon, L. Joseph, B. | J Am Coll Surg | 2020 | |
| Effect of moderate hypothermic circulatory arrest on neurological outcomes in elderly patients undergoing replacement of the thoracic aorta | Salem, M. Friedrich, C. Thiem, A. Salem, M. A. Puehler, T. Rusch, R. Berndt, R. Cremer, J. Haneya, A. | Egypt Heart J | 2020 |
Aging |
| Epigenetics of neuroinflammation: Immune response, inflammatory response and cholinergic synaptic involvement evidenced by genome-wide DNA methylation analysis of delirious inpatients | Saito, T. Toda, H. Duncan, G. N. Jellison, S. S. Yu, T. Klisares, M. J. Daniel, S. Andreasen, A. J. Leyden, L. R. Hellman, M. M. Shinozaki, E. Lee, S. Yoshino, A. Cho, H. R. Shinozaki, G. | J Psychiatr Res | 2020 |
Aging |
| Major surgery induces acute changes in measured DNA methylation associated with immune response pathways | Sadahiro, R. Knight, B. James, F. Hannon, E. Charity, J. Daniels, I. R. Burrage, J. Knox, O. Crawford, B. Smart, N. J. Mill, J. | Sci Rep | 2020 | |
| Basic geriatric principles for colorectal surgeons: How to optimize assessment and care of older patients in the perioperative period | Rostoft, S. Hamaker, M. E. | Eur J Surg Oncol | 2020 |
Cognition |
| The association of delirium severity with patient and health system outcomes in hospitalised patients: a systematic review | Rosgen, B. K. Krewulak, K. D. Stelfox, H. T. Ely, E. W. Davidson, J. E. Fiest, K. M. | Age Ageing | 2020 |
delirium |
| Reporting of Outcomes and Outcome Measures in Studies of Interventions to Prevent and/or Treat Delirium in the Critically Ill: A Systematic Review | Rose, L. Agar, M. Burry, L. Campbell, N. Clarke, M. Lee, J. Marshall, J. Siddiqi, N. Page, V. | Crit Care Med | 2020 | |
| Abdominal aortic aneurysm patients remain at risk for delirium on the surgical ward after intensive care unit dismissal | Roijers, J. P. Spillenaar Bilgen, R. Hopmans, C. J. Mulder, P. G. Buimer, M. G. Ho, G. H. de Groot, H. G. Veen, E. J. Besselink-Lobanova, A. van der Meer, N. J. van der Laan, L. | Minerva Anestesiol | 2020 | |
| Psychiatric and neuropsychiatric presentations associated with severe coronavirus infections: a systematic review and meta-analysis with comparison to the COVID-19 pandemic | Rogers, J. P. Chesney, E. Oliver, D. Pollak, T. A. McGuire, P. Fusar-Poli, P. Zandi, M. S. Lewis, G. David, A. S. | Lancet Psychiatry | 2020 |
Coronavirus Infections/ complications |
| Characterisation and outcome of neuropsychiatric symptoms in patients with anti-NMDAR encephalitis | Restrepo-Martinez, M. Ramirez-Bermudez, J. Bayliss, L. Espinola-Nadurille, M. | Acta Neuropsychiatr | 2020 |
anti-N-methyl-D-aspartate receptor encephalitis |
| Delirious mania as a frequent and recognizable neuropsychiatric syndrome in patients with anti-NMDAR encephalitis | Restrepo-Martinez, M. Ramirez-Bermudez, J. Bayliss, L. Espinola-Nadurille, M. | Gen Hosp Psychiatry | 2020 |
Anti-NMDA receptor encephalitis |
| Diffusion tensor imaging and resting-state functional magnetic resonance imaging in patients with delirium in intensive care unit | Renjie, S. Ganjun, S. Peng, X. Haizhen, D. Tianxi, Z. Yuanlan, L. Mo, L. Xiaoyun, F. | Zhonghua Wei Zhong Bing Ji Jiu Yi Xue | 2020 |
sedative agent |
| Mortality of gerontopsychiatric inpatients in Graz, Austria—a retrospective case-control study | Rásky, É Stolz, E. Jagsch, C. | Neuropsychiatrie | 2020 |
article |
| Barriers to rehabilitation after critical illness: a survey of multidisciplinary healthcare professionals caring for ICU survivors in an acute care hospital | Rai, S. Anthony, L. Needham, D. M. Georgousopoulou, E. N. Sudheer, B. Brown, R. Mitchell, I. van Haren, F. | Aust Crit Care | 2020 |
Intensive care |
| Older Patients with Alzheimer's Disease-Related Cortical Atrophy Who Develop Post-Operative Delirium May Be at Increased Risk of Long-Term Cognitive Decline after Surgery | Racine, A. M. Touroutoglou, A. Abrantes, T. Wong, B. Fong, T. G. Cavallari, M. Travison, T. G. Gou, Y. Marcantonio, E. R. Alsop, D. C. Jones, R. N. Inouye, S. K. Dickerson, B. C. | Journal of Alzheimer's Disease | 2020 |
aged |
| Psychiatric comorbidities in cancer patients: acute interventions by the psychiatric consultation liaison service | Quante, A. Schulz, K. Fissler, M. | Wiener Medizinische Wochenschrift | 2020 |
adult |
| Delirium is associated with higher mortality in transcatheter aortic valve replacement: systemic review and meta-analysis | Prasitlumkum, N. Mekritthikrai, R. Kewcharoen, J. Kanitsoraphan, C. Mao, M. A. Cheungpasitporn, W. | Cardiovasc Interv Ther | 2020 |
Delirium |
| A novel geriatric assessment tool that predicts postoperative complications in older adults with cancer | Pollock, Y. Chan, C. L. Hall, K. Englesbe, M. Diehl, K. M. Min, L. | J Geriatr Oncol | 2020 |
Functional decline |
| Modifiable factors associated with postoperative delirium after hip fracture repair: An age-stratified retrospective cohort study | Poeran, J. Cozowicz, C. Zubizarreta, N. Weinstein, S. M. Deiner, S. G. Leipzig, R. M. Friedman, J. I. Liu, J. Mazumdar, M. Memtsoudis, S. G. | Eur J Anaesthesiol | 2020 | |
| Downregulation of synapse-associated protein expression and loss of homeostatic microglial control in cerebrospinal fluid of infectious patients with delirium and patients with Alzheimer's disease | Peters van Ton, A. M. Verbeek, M. M. Alkema, W. Pickkers, P. Abdo, W. F. | Brain Behav Immun | 2020 |
Alzheimer’s disease |
| Documentation of acute change in mental status in nursing homes highlights opportunity to augment infection surveillance criteria | Penna, A. R. Sancken, C. L. Stone, N. D. Eure, T. R. Bamberg, W. Barney, G. Barter, D. Carswell, S. Clogher, P. Dumyati, G. Felsen, C. B. Frank, L. Godine, D. Johnston, H. Kainer, M. A. Li, L. Lynfield, R. Mahoehney, J. P. Nadle, J. Pierce, R. Ray, S. M. | Infect Control Hosp Epidemiol | 2020 | |
| Effect of Dexmedetomidine on Cardiac Surgery-Associated Acute Kidney Injury: A Meta-Analysis With Trial Sequential Analysis of Randomized Controlled Trials | Peng, K. Li, D. Applegate, R. L., 2nd Lubarsky, D. A. Ji, F. H. Liu, H. | J Cardiothorac Vasc Anesth | 2020 |
acute kidney injury |
| Electroencephalogram Burst-suppression during Cardiopulmonary Bypass in Elderly Patients Mediates Postoperative Delirium | Pedemonte, J. C. Plummer, G. S. Chamadia, S. Locascio, J. J. Hahm, E. Ethridge, B. Gitlin, J. Ibala, R. Mekonnen, J. Colon, K. M. Westover, M. B. D'Alessandro, D. A. Tolis, G. Houle, T. Shelton, K. T. Qu, J. Akeju, O. | Anesthesiology | 2020 | |
| Evaluating delirium outcomes among older adults in the surgical intensive care unit | Pavone, K. J. Jablonski, J. Junker, P. Cacchione, P. Z. Compton, P. Polomano, R. C. | Heart Lung | 2020 |
Critical care |
| Association between continuous deep sedation and survival time in terminally ill cancer patients | Park, S. J. Ahn, H. K. Ahn, H. Y. Han, K. T. Hwang, I. C. | Support Care Cancer | 2020 |
Continuous deep sedation |
| Liver Transplant Patients with High Preoperative Serum Bilirubin Levels Are at Increased Risk of Postoperative Delirium: A Retrospective Study | Park, K. H. Son, H. J. Choi, Y. J. Park, G. H. Lee, Y. S. Park, J. Y. Ri, H. S. Shim, J. R. | J Clin Med | 2020 |
bilirubin |
| Smoking-cessation pharmacotherapy for patients with stroke and TIA: Systematic review | Parikh, N. S. Salehi Omran, S. Kamel, H. Elkind, M. S. V. Willey, J. Z. | J Clin Neurosci | 2020 |
Cerebrovascular Disease |
| A prospective cohort study on predictors of mortality of delirium in an emergency observational unit | Pal, S. Sharma, N. Singh, S. M. Bhutungru, S. Pannu, A. K. | QJM | 2020 |
Acute confusional state |
| Preoperative Anxiety and Depression Increases the Incidence of Delirium After Coronary Artery Bypass Graft Surgery | Pakrad, F. Pakrad, E. Darvishi, N. Poorolajal, J. | J Perianesth Nurs | 2020 |
anxiety |
| Association between fluid overload and delirium/coma in mechanically ventilated patients | Ouchi, A. Sakuramoto, H. Hoshino, H. Matsuishi, Y. Sakaguchi, T. Enomoto, Y. Hoshino, T. Shimojo, N. Inoue, Y. | Acute Med Surg | 2020 |
Brain dysfunction |
| Hallucinations after Cardiac Surgery: A Prospective Observational Study | Ottens, T. H. Sommer, I. E. C. Begemann, M. J. Schutte, M. Cramer, M. J. Suyker, W. J. Van Dijk, D. Slooter, A. J. C. | Medicina (Kaunas) | 2020 |
cardiothoracic surgery |
| Preoperative sepsis is a predictive factor for 30-day mortality after major lower limb amputation among patients with arteriosclerosis obliterans and diabetes | Otsuka, T. Arai, M. Sugimura, K. Sakai, M. Nishizawa, Y. Suzuki, Y. Okamoto, H. Kuroiwa, M. | J Orthop Sci | 2020 | |
| Patient-related and anesthesia-dependent determinants for postoperative delirium after oral and maxillofacial surgery. Results from a register-based case-control study | Ortner, F. Eberl, M. Otto, S. Wang, B. Schauberger, G. Hofmann-Kiefer, K. Saller, T. | J Stomatol Oral Maxillofac Surg | 2020 |
Dementia |
| Investigation of Free-Flap Transfer Reconstruction in Elderly Patients and Oral Intake Function | Onoda, S. Kinoshita, M. Ariyoshi, Y. | J Craniofac Surg | 2020 | |
| Delirium: a missing piece in the COVID-19 pandemic puzzle | O'Hanlon, S. Inouye, S. K. | Age Ageing | 2020 |
Covid-19 |
| Effects of Ramelteon on the Prevention of Postoperative Delirium in Older Patients Undergoing Orthopedic Surgery: The RECOVER Randomized Controlled Trial | Oh, E. S. Leoutsakos, J. M. Rosenberg, P. B. Pletnikova, A. M. Khanuja, H. S. Sterling, R. S. Oni, J. K. Sieber, F. E. Fedarko, N. S. Akhlaghi, N. Neufeld, K. J. | Am J Geriatr Psychiatry | 2020 |
Delirium |
| A roadmap to advance delirium research: Recommendations from the NIDUS Scientific Think Tank | Oh, E. S. Akeju, O. Avidan, M. S. Cunningham, C. Hayden, K. M. Jones, R. N. Khachaturian, A. S. Khan, B. A. Marcantonio, E. R. Needham, D. M. Neufeld, K. J. Rose, L. Spence, J. Tieges, Z. Vlisides, P. Inouye, S. K. | Alzheimers Dement | 2020 |
biomarkers |
| Association between a prognostic nutritional index less than 50 and the risk of medical complications after adult spinal deformity surgery | Oe, S. Yamato, Y. Hasegawa, T. Yoshida, G. Kobayashi, S. Yasuda, T. Banno, T. Arima, H. Mihara, Y. Ushirozako, H. Yamada, T. Ide, K. Watanabe, Y. Matsuyama, Y. | J Neurosurg Spine | 2020 |
ASD = adult spinal deformity |
| Communication with patients in post-traumatic confusional state: perception of rehabilitation staff | Nielsen, A. I. Power, E. Jensen, L. R. | Brain Injury | 2020 |
comprehension |
| Singapore SPICE: Sedation practices in intensive care evaluation in Singapore - A prospective cohort study of the public healthcare system | Ng, S. Y. Phua, J. Wong, Y. L. Kalyanasundaram, G. Mukhopadhyay, A. Lim, D. Chia, N. Ho, B. C. H. Bailey, M. J. Shehabi, Y. Ti, L. K. | Singapore Medical Journal | 2020 |
dexmedetomidine |
| Association of obstructive sleep apnea and postoperative cardiac complications: A systematic review and meta-analysis with trial sequential analysis | Ng, K. T. Lee, Z. X. Ang, E. Teoh, W. Y. Wang, C. Y. | J Clin Anesth | 2020 |
Cardiac complications |
| Long-term mortality in very old patients with cancer admitted to intensive care unit: A retrospective cohort study | Nassar Junior, A. P. Trevisani, M. D. S. Bettim, B. B. Caruso, P. | J Geriatr Oncol | 2020 |
Aged 80 and over |
| Functional Outcomes of Frail Patients after Cardiac Surgery: An Observational Study | Nakano, M. Nomura, Y. Suffredini, G. Bush, B. Tian, J. Yamaguchi, A. Walston, J. Hasan, R. Mandal, K. Schena, S. Hogue, C. W. Brown, C. H. | Anesthesia and Analgesia | 2020 |
adult |
| Development of a clinical score, PANDA, to predict delirium in stroke care unit | Nakamizo, T. Kanda, T. Kudo, Y. Sugawara, E. Hashimoto, E. Okazaki, A. Usuda, M. Nagai, T. Hara, H. Johkura, K. | J Neurol Sci | 2020 |
Area under curve |
| Impact of Tobacco Smoking on Outcomes after Posterior Decompression Surgery in Patients with Cervical Spondylotic Myelopathy: A Retrospective Multicenter Study | Nagoshi, N. Kono, H. Tsuji, O. Aoyama, R. Fujiyoshi, K. Shiono, Y. Ishikawa, M. Daimon, K. Hosogane, N. Takeuchi, A. Okada, E. Fujita, N. Yagi, M. Nakamura, M. Matsumoto, M. Watanabe, K. Ishii, K. Yamane, J. | Clinical Spine Surgery | 2020 |
adult |
| Role of omega-3 fatty acids in the prevention of delirium in mechanically ventilated patients | Naghibi, T. Shafigh, N. Mazloomzadeh, S. | Journal of Research in Medical Sciences | 2020 |
IRCT2015095536N5 |
| Brain BOLD MRI O(2) and CO(2) stress testing: implications for perioperative neurocognitive disorder following surgery | Mutch, W. A. C. El-Gabalawy, R. Ryner, L. Puig, J. Essig, M. Kilborn, K. Fidler, K. Graham, M. R. | Crit Care | 2020 |
Anesthesia |
| Off-label use of quetiapine in nursing homes: Does medical specialty of prescribing physicians play a role? | Müller, L. Noseda, R. Bertoli, R. Bissig, M. Ceschi, A. | British Journal of Clinical Pharmacology | 2020 |
quetiapine |
| Multidisciplinary quality improvement programme for older patients admitted to a vascular surgery ward() | Mudge, A. M. McRae, P. Donovan, P. J. Reade, M. C. | Intern Med J | 2020 |
delirium |
| Cross-cultural adaptation and validation of the 3D-CAM Chinese version in surgical ICU patients | Mu, D. L. Ding, P. P. Zhou, S. Z. Liu, M. J. Sun, X. Y. Li, X. Y. Wang, D. X. | BMC Psychiatry | 2020 |
3d-cam |
| Thiamine for Prevention of Postoperative Delirium in Patients Undergoing Gastrointestinal Surgery: A Randomized Clinical Trial | Moslemi, R. Khalili, H. Mohammadi, M. Mehrabi, Z. Mohebbi, N. | J Res Pharm Pract | 2020 |
Delirium |
| How successful are we in relieving terminal dyspnea in cancer patients? A real-world multicenter prospective observational study | Mori, M. Morita, T. Matsuda, Y. Yamada, H. Kaneishi, K. Matsumoto, Y. Matsuo, N. Odagiri, T. Aruga, E. Watanabe, H. Tatara, R. Sakurai, H. Kimura, A. Katayama, H. Suga, A. Nishi, T. Shirado, A. N. Watanabe, T. Kuchiba, A. Yamaguchi, T. Iwase, S. | Supportive Care in Cancer | 2020 | |
| Understanding Factors Associated With Psychomotor Subtypes of Delirium in Older Inpatients With Dementia | Morandi, A. Zambon, A. Di Santo, S. G. Mazzone, A. Cherubini, A. Mossello, E. Bo, M. Marengoni, A. Bellelli, G. | Journal of the American Medical Directors Association | 2020 |
intravenous catheter |
| Infection in older adults: a qualitative study of patient experience | Moore, A. McKelvie, S. Glogowska, M. Lasserson, D. Hayward, G. | Br J Gen Pract | 2020 |
aged |
| Aripiprazole for prevention of delirium in the neurosurgical intensive care unit: a double-blind, randomized, placebo-controlled study | Mokhtari, M. Farasatinasab, M. Jafarpour Machian, M. Yaseri, M. Ghorbani, M. Ramak Hashemi, S. M. Nikoobakht, M. Golchin, N. Mohammadi, G. Sistanizad, M. | Eur J Clin Pharmacol | 2020 |
Aripiprazole |
| Potentially Inappropriate Medications in a Psychogeriatric Inpatient Ward: An Audit Based on Beers Criteria | Moebs, I. Abeln, E. Siefert, A. Barak, Y. | Neurology and Therapy | 2020 |
adult |
| An 11-year review of hip fracture hospitalisations, health outcomes, and predictors of access to in-hospital rehabilitation for adults ≥ 65 years living with and without dementia: a population-based cohort study | Mitchell, R. Draper, B. Brodaty, H. Close, J. Ting, H. P. Lystad, R. Harris, I. Harvey, L. Sherrington, C. Cameron, I. D. Braithwaite, J. | Osteoporos Int | 2020 |
Aged care |
| Evaluation of a co-produced delirium awareness programme for undergraduate nursing students in Northern Ireland: a pre-test/post-test study | Mitchell, G. McVeigh, C. Carlisle, S. Brown-Wilson, C. | BMC Nurs | 2020 |
Co-design |
| Perioperative dexmedetomidine and postoperative delirium in non-cardiac surgery: a meta-analysis | Ming, S. Zhang, X. Gong, Z. Xie, Y. Xie, Y. | Ann Palliat Med | 2020 |
Dexmedetomidine |
| Cholinesterases and Anticholinergic Medications in Postoperative Pediatric Delirium | Meyburg, J. Ritsert, M. L. Traube, C. Plaschke, K. von Haken, R. | Pediatr Crit Care Med | 2020 | |
| Comparison of novel tools with traditional cognitive tests in detecting delirium in elderly medical patients | Meagher, D. J. O'Connell, H. Leonard, M. Williams, O. Awan, F. Exton, C. Tenorio, M. O'Connor, M. Dunne, C. P. Cullen, W. McFarland, J. Adamis, D. | World J Psychiatry | 2020 |
Assessment |
| A systematic review and meta-analysis of the accuracy of the clock drawing test (CDT) in the identification of delirium in older hospitalised patients | Meagher, D. Williams, O. A. O'Connell, H. Leonard, M. Cullen, W. Dunne, C. P. Mulligan, O. Adamis, D. | Aging & mental health | 2020 |
adult |
| Family intervention improves outcomes for patients with delirium: Systematic review and meta-analysis | McKenzie, J. Joy, A. | Australas J Ageing | 2020 |
caregivers |
| Effectiveness and Safety of Intrathecal Ziconotide: Final Results of the Patient Registry of Intrathecal Ziconotide Management (PRIZM) | McDowell, G. C. Saulino, M. F. Wallace, M. Grigsby, E. J. Rauck, R. L. Kim, P. Vanhove, G. F. Ryan, R. Huang, I. Z. Deer, T. | Pain medicine (Malden, Mass.) | 2020 |
adult |
| Management Effort for Delirium and Insomnia in Patients with Acute Ischemic Stroke (MEDIAS) Study | Matsuzono, K. Mashiko, T. Ozawa, T. Miura, K. Suzuki, M. Furuya, K. Ozawa, M. Anan, Y. Shimazaki, H. Koide, R. Tanaka, R. Fujimoto, S. | Psychiatry Clin Neurosci | 2020 |