NIDUS Delirium Bibliography

Delirium Bibliography books graphic What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!

How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.

Reference Information

Title: Validation of the delirium diagnostic tool-provisional (DDT-Pro) in geriatric medical inpatients with diagnostic permutations of the 3Ds with and without delirium

Authors: Botero Urrea, M. González, M. C. Villa García, M. M. Alviz Núñez, M. Velásquez-Tirado, J. D. Ocampo, M. V. Trzepacz, P. T. Franco, J. G.

Year: 2024

Journal: J Psychosom Res

Abstract: OBJECTIVE: Validations of brief delirium tools have not included analysis of psychiatric disorders comorbidities or control groups. We validated the Delirium Diagnostic Tool-Provisional (DDT-Pro) in 422 geriatric inpatients with high incidence of depression and/or dementia. METHODS: Cross-sectional study using two delirium reference standards, DSM-5-TR and Delirium Rating Scale-Revised-98 (DRS-R98). We assessed concurrent and construct DDT-Pro validity too. RESULTS: There were 117 (27.7%) delirium cases using DDT-Pro, 104 (24.6%) per DSM-5-TR and 93 (22.0%) per DRS-R98; 133 patients (31.5%) had depression and 105 (24.9%) dementia, some comorbid with delirium. DDT-Pro accuracy (AUC under ROC curve) ranges were 88.3-95.9% vs DSM-5-TR and 92.7-95.0% vs DRS-R98 for whole sample and four diagnostic groups, without statistical differences. DDT-Pro ≤6 had the most balanced sensitivity-specificity for delirium diagnosis against both DSM-5-TR and DRS-R98 with similar specificity but higher sensitivity for DRS-R98 than DSM-5-TR delirium, with the highest values in patients with depression and dementia (≥92% sensitivity, ≥81% specificity). Positive and negative likelihood ratios support diagnostic strength. Concurrent validity was high reflected by significant correlations (p < 0.001) of DDT-Pro total and item scores with DRS-R98 and Delirium Frontal Index scores, highest in groups with comorbid depression and/or dementia. The DDT-Pro represented a single construct for delirium demonstrated by one factor with high item loadings and high internal consistency reliability of its items. CONCLUSIONS: The DDT-Pro demonstrated strong performance metrics in general hospital elderly inpatients with preexisting depression and/or dementia, which is unique among brief delirium tools. Its optimized cutoff score was the same as in other populations.

PMID: PMID: 39126891

Keywords: Humans

Female
Male
Aged
Cross-Sectional Studies
Aged, 80 and over
*Delirium/diagnosis
*Sensitivity and Specificity
*Dementia/diagnosis
Inpatients
Reproducibility of Results
Depression/diagnosis
Diagnostic and Statistical Manual of Mental Disorders
Comorbidity
Psychiatric Status Rating Scales
Delirium diagnosis
Dementia
Depression
Geriatric assessment
Validation studies

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Volume

Issue

Total Records Found: 6831, showing 100 per page
Title	Authors	Journal	Year	Keywords
Italian version of the short 10/66 dementia diagnostic schedule: a validation study	Ibnidris, A. Piumatti, G. Carlevaro, F. Fadda, M. Magno, F. Magistro, D. Albanese, E.	BMJ Open	2021	Aged Cross-Sectional Studies Dementia/diagnosis Female Humans Italy/epidemiology Male Middle Aged ROC Curve Switzerland delirium & cognitive disorders dementia old age psychiatry
A Machine Learning-Based Algorithm for the Prediction of Intensive Care Unit Delirium (PRIDE): Retrospective Study	Hur, S. Ko, R. E. Yoo, J. Ha, J. Cha, W. C. Chung, C. R.	JMIR Med Inform	2021	clinical prediction delirium electronic health record intensive care unit machine learning
The effect of evidence-based cluster nursing intervention on the incidences of delirium and the prognoses of ICU patients	Huang, S. Xu, J. Du, Y. Wang, Y. Wei, H. Wei, G. Hu, M.	Am J Transl Res	2021	Evidence-based medicine Icu cluster nursing intervention delirium prognosis
Impact of dexmedetomidine supplemented analgesia on delirium in patients recovering from orthopedic surgery: A randomized controlled tria	Hong, H. Zhang, D. Z. Li, M. Wang, G. Zhu, S. N. Zhang, Y. Wang, D. X. Sessler, D. I.	BMC Anesthesiol	2021	Delirium Dexmedetomidine Elderly Orthopedic Procedures Postoperative Period
Effects of a simulation-based education programme on delirium care for critical care nurses: A randomized controlled trial	Ho, M. H. Yu, L. F. Lin, P. H. Chang, H. R. Traynor, V. Huang, W. C. Montayre, J. Chen, K. H.	J Adv Nurs	2021	Clinical Competence Critical Care Delirium Humans Nurses Taiwan competence confidence delirium knowledge nurses simulation
Postoperative Delirium in Older Patients: A Systematic Review of Assessment and Incidence of Postoperative Delirium	Ho, M. H. Nealon, J. Igwe, E. Traynor, V. Chang, H. R. Chen, K. H. Montayre, J.	Worldviews Evid Based Nurs	2021	Aged Checklist Cohort Studies *Delirium/epidemiology/etiology Humans Incidence Risk Factors data pooling epidemiology geriatrics gerontology healthcare outcomes meta-analysis nervous system diseases neurology patient outcomes
Harmonization of Four Delirium Instruments: Creating Crosswalks and the Delirium Item-Bank (DEL-IB)	Helfand, B. K. I. Detroyer, E. Milisen, K. Adamis, D. Metzger, E. D. Boudreaux, E. D. Inouye, S. K. Jones, R. N.	Am J Geriatr Psychiatry	2021
Association between genetic variants of the cholinergic system and postoperative delirium and cognitive dysfunction in elderly patients	Heinrich, M. Sieg, M. Kruppa, J. Nürnberg, P. Schreier, P. H. Heilmann-Heimbach, S. Hoffmann, P. Nöthen, M. M. Janke, J. Pischon, T. Slooter, A. J. C. Winterer, G. Spies, C. D.	BMC Med Genomics	2021	Chrm2 Chrm4 Genome-wide association study Neurocognitive disorder
Risk of delirium and impaired neurological outcome associated with delay in neurorehabilitation after acquired brain injury	Hansen, P. M. Lauridsen, J. T. Frandsen, N. S.	Dan Med J	2021	Brain Injuries Delirium/etiology Glasgow Coma Scale Humans Neurological Rehabilitation Stroke
Prevalence, Risk Factors, and Impact of Delirium on Hospitalized Older Adults With Dementia: A Systematic Review and Meta-Analysis	Han, Q. Y. C. Rodrigues, N. G. Klainin-Yobas, P. Haugan, G. Wu, X.	J Am Med Dir Assoc	2021	Dementia delirium delirium superimposed on dementia meta-analysis older adults prevalence risk factors
Urinary albumin creatinine ratio associated with postoperative delirium in elderly patients undergoing elective non-cardiac surgery: A prospective observational study	Guan, H. L. Liu, H. Hu, X. Y. Abdul, M. Dai, M. S. Gao, X. Chen, X. F. Zhou, Y. Sun, X. Zhou, J. Li, X. Zhao, Q. Zhang, Q. Q. Wang, J. Han, Y. Cao, J. L.	CNS Neurosci Ther	2021	delirium elderly patient the blood-brain barrier urinary albumin creatinine ratio
Cognitive Impairment and Delirium in Older Patients Undergoing Major Head and Neck Surgery	Goldstein, D. P. Blasco, M. de Almeida, J. Su, J. Xu, W. Cohen, M. Sklar, M. Alibhai, S	Otolaryngol Head Neck Surg	2021	clock draw test cognitive impairment delirium head neck surgery older patients
What prompts patients to present with delirium?	Gibb, K. Krywonos, A. Shah, R. Jha, A. Davis, D.	Eur Geriatr Med	2021	Adult Aged, 80 and over Caregivers Delirium/diagnosis Hospitalization Humans Surveys and Questionnaires Awareness Delirium Recognition *Response
Admission Systolic Blood Pressure Predicts Post-Operative Delirium of Acute Aortic Dissection Patients in the Intensive Care Unit	Fu, Z. Xu, Q. Zhang, C. Bai, H. Chen, X. Zhang, Y. Luo, W. Lin, G.	Int J Gen Med	2021	acute Stanford type A aortic dissection intensive care unit major surgery post-operative delirium systolic blood pressure
Postoperative Delirium in Patients After Brain Tumor Surgery	French, J. Weber, T. Ge, B. Litofsky, N. S.	World Neurosurg	2021	Confusion assessment method Delirium Recognition Tumor resection
Physical Restraints and Post-Traumatic Stress Disorder in Survivors of Critical Illness. A Systematic Review and Meta-analysis	Franks, Z. M. Alcock, J. A. Lam, T. Haines, K. J. Arora, N. Ramanan, M.	Ann Am Thorac Soc	2021	Adult Critical Illness Humans Intensive Care Units Randomized Controlled Trials as Topic Restraint, Physical Stress Disorders, Post-Traumatic/etiology/prevention & control Survivors critical care delirium physical restraint post-traumatic stress disorder *post–intensive care syndrome
Long-Term Outcomes in ICU Patients with Delirium: A Population-based Cohort Study	Fiest, K. M. Soo, A. Hee Lee, C. Niven, D. J. Ely, E. W. Doig, C. J. Stelfox, H. T.	Am J Respir Crit Care Med	2021	Adolescent Adult Aged Aged, 80 and over Alberta/epidemiology Critical Illness Delirium/mortality Facilities and Services Utilization/statistics & numerical data Female Follow-Up Studies Humans Intensive Care Units Male Middle Aged Patient Discharge Prognosis Propensity Score Retrospective Studies Survival Analysis Young Adult critical care delirium mortality
The effect of foot reflexology massage on delirium and sleep quality following cardiac surgery: A randomized clinical trial	Fazlollah, A. Babatabar Darzi, H. Heidaranlu, E. Moradian, S. T.	Complement Ther Med	2021	Cardiac Surgical Procedures/adverse effects Delirium/etiology/therapy Humans Massage Musculoskeletal Manipulations Sleep *Sleep Wake Disorders/etiology/therapy Cardiac surgical procedure Delirium Massage Pain measurement Sleep hygiene
A delirium prevalence audit and a pre and post evaluation of an interprofessional education intervention to increase staff knowledge about delirium in older adults	Ewens, B. Seaman, K. Whitehead, L. Towell-Barnard, A. Young, M.	BMC Nurs	2021	Delirium Delirium assessment Delirium knowledge Interprofessional education, quality improvement Symptom recognition
Anaesthetic depth and delirium after major surgery: a randomised clinical trial	Evered, L. A. Chan, M. T. V. Han, R. Chu, M. H. M. Cheng, B. P. Scott, D. A. Pryor, K. O. Sessler, D. I. Veselis, R. Frampton, C. Sumner, M. Ayeni, A. Myles, P. S. Campbell, D. Leslie, K. Short, T. G.	Br J Anaesth	2021	anaesthesia bispectral index cognitive dysfunction delirium electroencephalography postoperative delirium
Association of preoperative frailty with postoperative delirium in elderly orthopedic trauma patients	Esmaeeli, S. Franco-Garcia, E. Akeju, O. Heng, M. Zhou, C. Azocar, R. J. Quraishi, S. A.	Aging Clin Exp Res	2021	Cognition Delirium Frailty Postoperative delirium Trauma
Prevention of postoperative delirium after cardiovascular surgery: A team-based approach	Enomoto, K. Kosaka, S. Kimura, T. Matsubara, M. Kitada, Y. Mieno, M. Okamura, H.	J Thorac Cardiovasc Surg	2021	Delirium Team Approach program benzodiazepine cardiovascular surgery postoperative delirium
Serum Levels of S100β, Neuron-Specific Enolase, Glial Fibrillary Acidic Protein in Kidney Transplant Recipients and Donors: A Prospective Cohort Study	Dinc, B. Yılmaz, V. T. Aslan, M. Aycan, I. O. Kiraz, N. Kisaoglu, A. Dandin, O. Hadimioglu, N. Ertug, Z.	Transplant Proc	2021	Nephrectomy, Kidney transplant, Neuromarkers, Postoperative delirium
Delirium and Its Pharmacological Causes in Older People, Part 1	DeMaagd, G. A. DeMaagd, D. R. Philip, A. Coalter, C. F.	Sr Care Pharm	2021	Aged *Delirium/chemically induced/diagnosis/epidemiology Human
Potentially inappropriate prescribing in dementia, multi-morbidity and incidence of adverse health outcomes	Delgado, J. Jones, L. Bradley, M. C. Allan, L. M. Ballard, C. Clare, L. Fortinsky, R. H. Hughes, C. M. Melzer, D.	Age Ageing	2021	Aged Aged, 80 and over Dementia/diagnosis/drug therapy/epidemiology England/epidemiology Humans Inappropriate Prescribing Incidence Multimorbidity Outcome Assessment, Health Care Potentially Inappropriate Medication List Retrospective Studies Alzheimer’s Beer’s Parkinson’s delirium hospitalisation misprescribing mortality older people *vascular dementia
The Nexus Between Sleep Disturbance and Delirium Among Intensive Care Patients	Delaney, L. J. Litton, E. Van Haren, F.	Crit Care Nurs Clin North Am	2021	Critical Care Delirium/epidemiology Humans Intensive Care Units Sleep Sleep Wake Disorders/epidemiology Delirium Intensive care Light Noise Sleep disturbance
Opportunities for quality improvement in the morbidity pattern of older adults undergoing pulmonary lobectomy for cancer	De León, L. E. Rochefort, M. M. Bravo-Iñiguez, C. E. Fox, S. W. Tarascio, J. N. Cardin, K. DuMontier, C. Frain, L. N. Jaklitsch, M. T.	J Geriatr Oncol	2021	Aged Humans Length of Stay Lung Neoplasms/surgery Morbidity Postoperative Complications/epidemiology Quality Improvement Retrospective Studies Thoracic Surgery, Video-Assisted Thoracotomy Lobectomy Minimally invasive surgery Morbidity Older adult Oncology outcomes Postoperative outcomes *Thoracic surgery
Palliative sedation in patients with advanced cancer in a specialized unit in a middle-income country: A retrospective cohort study	de Araujo, C. Z. S. de Araújo, L. Z. S. Nassar Junior, A. P.	Palliat Support Care	2021	Cancer Cancer care facilities Deep sedation End-of-life care Palliative care
Development and Implementation of a Multicomponent Protocol to Promote Sleep and Reduce Delirium in a Medical Intensive Care Unit	Darby, A. Northam, K. Austin, C. A. Chang, L. Campbell-Bright, S	Ann Pharmacother	2021	critical care mechanical ventilators quality assurance sedatives sleep disorders
Effect of Interventions With a Clinical Decision Support System for Hospitalized Older Patients: Systematic Review Mapping Implementation and Design Factors	Damoiseaux-Volman, B. A. van der Velde, N. Ruige, S. G. Romijn, J. A. Abu-Hanna, A. Medlock, S.	JMIR Med Inform	2021	aged clinical decision support systems geriatrics hospital quality of care
Sevoflurane-Remifentanil Versus Propofol-Remifentanil Anesthesia During Noncardiac Surgery for Patients with Coronary Artery Disease - A Prospective Study Between 2016 and 2017 at a Single Center	Dai, Z. Lin, M. Li, Y. Gao, W. Wang, P. Lin, J. Wan, Z. Jiang, Y.	Med Sci Monit	2021	Acute Coronary Syndrome, Coronary Artery Disease, Propofol
Symptom trajectories for palliative care inpatients with and without hyperactive delirium in the last week of life	Dai, Y. Walpole, G. Ding, J. Scanlon, C. Ho, L. Khoo, R. H. Huang, C. Cook, A. William, L. Johnson, C. E.	J Adv Nurs	2021	end of life hyperactive delirium inpatient palliative care nurse caring symptom trajectory
Subtypes of delirium after ischaemic stroke-predisposing factors and outcomes: a prospective observational study (PROPOLIS)	Czyzycki, M. Klimiec-Moskal, E. Chrobak, A. A. Pera, J. Slowik, A. Dziedzic, T.	Eur J Neurol	2021	delirium motor subtypes neuropsychiatric disturbances outcome stroke
Effectiveness of a Delirium Prevention Initiative on an Inpatient Neuroscience Unit	Cyrus, T. Wenthold, R. Hall, B. Tu, L. Hedquist, K. Omodt, J. Kozub, E. Guthrie, P. F.	J Neurosci Nurs	2021	Clinical Competence Delirium/prevention & control Humans Inpatients Nurses Quality Improvement
Association Between Cerebral Desaturation and Postoperative Delirium in Thoracotomy With One-Lung Ventilation: A Prospective Cohort Study	Cui, F. Zhao, W. Mu, D. L. Zhao, X. Li, X. Y. Wang, D. X. Jia, H. Q. Dai, F. Meng, L.	Anesth Analg	2021	Aged Cerebrovascular Circulation/physiology Cohort Studies Delirium/diagnosis/etiology/physiopathology Female Humans Male Middle Aged One-Lung Ventilation/adverse effects/trends Postoperative Cognitive Complications/diagnosis/etiology/physiopathology Prospective Studies Thoracotomy/*adverse effects/trends
Factors for Timely Identification of Possible Occurrence of Delirium in Palliative Care: A Prospective Observational Study	Corli, O. Santucci, C. Uggeri, S. Bosetti, C. Cattaneo, M. Ermolli, D. Varrassi, G. Myrcik, D. Paladini, A. Rekatsina, M. Gerosa, C. Ornaghi, M. Roccasalva, A. Santambrogio, P. Beretta, M.	Adv Ther	2021	Delirium/chemically induced/diagnosis/epidemiology Hospitalization Humans Palliative Care Proportional Hazards Models Prospective Studies Risk Factors Causality Clinical predisposing factors *Delirium
A Processed Electroencephalogram-Based Brain Anesthetic Resistance Index Is Associated With Postoperative Delirium in Older Adults: A Dual Center Study	Cooter Wright, M. Bunning, T. Eleswarpu, S. S. Heflin, M. T. McDonald, S. R. Lagoo-Deenadalayan, S. Whitson, H. E. Martinez-Camblor, P. Deiner, S. G. Berger, M.	Anesth Analg	2021	age factors, anesthesia, methods, delirium, surgery/prevention & control, Electroencephalography, drug effects
Implementation and Routinization of the ABCDE Bundle: A Mixed Methods Evaluation	Collinsworth, A. W. Brown, R. Cole, L. Jungeblut, C. Kouznetsova, M. Qiu, T. Richter, K. M. Smith, S. Masica, A. L.	Dimens Crit Care Nurs	2021	Adult Critical Care *Delirium Humans Intensive Care Units Respiration, Artificial Surveys and Questionnaires
Prediction of delirium using data mining: A systematic review	Chua, S. J. Wrigley, S. Hair, C. Sahathevan, R	J Clin Neurosci	2021	Area Under Curve Data Mining *Delirium/diagnosis/epidemiology Humans Length of Stay Retrospective Studies Association mining Big data Delirium Machine learning Systematic review competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
Determinants of Non-emergency Use of Control Interventions in Older Canadian Psychiatric Inpatients: Analysizing the InterRAI Mental Health Electronic Health Records	Cheung, G. Mah, T. M. Barak, Y. Hirdes, J. P.	Front Psychiatry	2021	aggression control interventions delirium geriatric psychiatry restraints or financial relationships that could be construed as a potential conflict of interest.
Assessment of preoperative frailty and identification of patients at risk for postoperative delirium in cardiac intensive care units: a prospective observational study	Cheng, H. W. Liu, C. Y. Chen, Y. S. Shih, C. C. Chen, W. Y. Chiou, A. F.	Eur J Cardiovasc Nurs	2021	Anxiety Arrhythmia Cardiac surgery Delirium Depression Frailty
Preoperative prognostic nutritional index is useful factor for predicting postoperative delirium after primary total joint arthroplasty	Chen, J. Zheng, C. Zhong, J. Zhao, G. Shi, J. Huang, G. Wei, Y. Wang, S. Yu, J. Xia, J.	BMC Musculoskelet Disord	2021	Aged Arthroplasty Delirium/diagnosis/epidemiology/etiology Humans Nutrition Assessment Prognosis Retrospective Studies Malnutrition Postoperative delirium Prognostic nutritional index Risk factor Total joint arthroplasty
Case-control study on the interplay between immunoparalysis and delirium after cardiac surgery	CheheiliSobbi, S. Peters van Ton, A. M. Wesselink, E. M. Looije, M. F. Gerretsen, J. Morshuis, W. J. Slooter, A. J. C. Abdo, W. F. Pickkers, P. van den Boogaard, M.	J Cardiothorac Surg	2021	Cardiac Surgical Procedures/adverse effects Case-Control Studies Cytokines Delirium/etiology Humans Prospective Studies Tumor Necrosis Factor-alpha Cardiothoracic surgery Delirium Immunity Intensive care medicine
Diagnostic accuracy of the "4 A's Test" delirium screening tool for the postoperative cardiac surgery ward	Chang, Y. Ragheb, S. M. Oravec, N. Kent, D. Nugent, K. Cornick, A. Hiebert, B. Rudolph, J. L. MacLullich, A. M. J. Arora, R. C.	J Thorac Cardiovasc Surg	2021	4at cardiac surgery nursing postoperative delirium
Meta-analysis of ICU Delirium Biomarkers and Their Alignment With the NIA-AA Research Framework	Chan, C. K. Song, Y. Greene, R. Lindroth, H. Khan, S. Rios, G. Khan, B. Wang, S	Am J Crit Care	2021	Alzheimer Disease Biomarkers Delirium/diagnosis Humans Intensive Care Units National Institute on Aging (U.S.) United States
Sedation strategy and ICU delirium: a multicentre, population-based propensity score-matched cohort study	Casault, C. Soo, A. Lee, C. H. Couillard, P. Niven, D. Stelfox, T. Fiest, K.	BMJ Open	2021	Adult Alberta Cohort Studies Delirium/chemically induced/epidemiology Female Humans Hypnotics and Sedatives/adverse effects Intensive Care Units Length of Stay Male Middle Aged Propensity Score Respiration, Artificial Retrospective Studies adult intensive & critical care delirium & cognitive disorders health & safety quality in health care
Health outcomes after the implementation of multidisciplinary clinical guidelines for the care of hip fractures	Casanova Querol, T. Santiago Bautista, J. M. Lafuente Salinas, M. Güell Farré, E. Girós Torres, J. Martín-Baranera, M. Miralles Basseda, R.	Rev Clin Esp (Barc)	2021	Atención continuada Continued care Fractura de cadera Hip fracture Internal Medicine Medicina Interna Orthogeriatrics Ortogeriatría
Pharmacological and non-pharmacological interventions to prevent delirium in critically ill patients: a systematic review and network meta-analysis	Burry, L. D. Cheng, W. Williamson, D. R. Adhikari, N. K. Egerod, I. Kanji, S. Martin, C. M. Hutton, B. Rose, L.	Intensive Care Med	2021	Adult Bayes Theorem Critical Illness Delirium/prevention & control Humans Network Meta-Analysis Randomized Controlled Trials as Topic Respiration, Artificial/adverse effects Critical care Delirium Non-pharmacological interventions Pharmacological *Prevention financial relationships with any organizations that might have an interest in the submitted work in the previous 3 years no other relationships or activities that could appear to have influenced the submitted work. BH has previously provided methodologic advice to Eversana Inc for the conduct of systemic reviews and meta-analysis on unrelated topics.
Dexmedetomidine for Facilitating Mechanical Ventilation Extubation in Difficult-to-Wean ICU Patients: Systematic Review and Meta-Analysis of Clinical Trials	Buckley, M. S. Smithburger, P. L. Wong, A. Fraser, G. L. Reade, M. C. Klein-Fedyshin, M. Ardiles, T. Kane-Gill, S. L.	J Intensive Care Med	2021	Adult Airway Extubation Critical Care Dexmedetomidine Humans Intensive Care Units Length of Stay Respiration, Artificial agitation delirium dexmedetomidine extubation intensive care mechanical ventilation weaning
Risk factors for postoperative delirium: An umbrella review of systematic reviews	Bramley, P. McArthur, K. Blayney, A. McCullagh, I.	Int J Surg	2021	Cognitive Dysfunction Delirium/epidemiology/etiology Humans Length of Stay Postoperative Complications/epidemiology/etiology Risk Factors Systematic Reviews as Topic Delirium Prognostic Risk factor Surgery Umbrella review
Inadequate emergence after anesthesia for elective cancer surgery: a single-center cohort study	Braga, A. Abelha, F.	Braz J Anesthesiol	2021	Cancer surgeries Emergence delirium Hypoactive emergence Inadequate emergence Quality of recovery
Asthma and delirium episodes during hospitalization	Bozek, A. Fiolka, R. Zajac, M.	Aging Med (Milton)	2021	asthma delirium
A pragmatic assessment of proton pump inhibitors vs. histamine type 2 receptor antagonists on clinically important gastrointestinal bleeding and mortality when used for stress ulcer prophylaxis in the ICU	Boyd, C. Hassig, T. MacLaren, R.	Pharmacotherapy	2021	critical illness delirium histamine H2 antagonists mortality peptic ulcer prevention and control proton pump inhibitors stress
Brain Network Dysfunction in Poststroke Delirium and Spatial Neglect: An fMRI Study	Boukrina, O. Kowalczyk, M. Koush, Y. Kong, Y. Barrett, A. M.	Stroke	2021	MRI, functional attention basal ganglia delirium incidence ischemic stroke prevalence
Preventing Delirium and Promoting Long-Term Brain Health: A Clinical Trial Design for the Perioperative Cognitive Enhancement (PROTECT) Trial	Atkins, K. J. Scott, D. A. Silbert, B. Pike, K. E. Evered, L.	J Alzheimers Dis	2021	Anesthesia and analgesia cognition delirium dementia healthy aging perioperative medicine prehabilitation preventive medicine rehabilitation
Prevalence of Severe Neurocognitive Impairment and Its Association with Socio-Demographics and Functionality Among Ugandan Older Persons: A Hospital-Based Study	Atim, L. M. Kaggwa, M. M. Mamun, M. A. Ashaba, S. Maling, S.	Clin Interv Aging	2021	Aged Aged, 80 and over *Cognition Disorders Cross-Sectional Studies Female Hospitals Humans Male Middle Aged Prevalence Uganda/epidemiology Barthel Index Mini-Mental Status Examination Ugandan elderly dementia early diagnosis functionality neurocognitive disorder prevalence and associated factors
Clinical Aspects of Palliative Sedation in Prospective Studies. A Systematic Review	Arantzamendi, M. Belar, A. Payne, S. Rijpstra, M. Preston, N. Menten, J. Van der Elst, M. Radbruch, L. Hasselaar, J. Centeno, C.	J Pain Symptom Manage	2021	Hospice and Palliative Care Nursing Humans Hypnotics and Sedatives/therapeutic use Palliative Care Prospective Studies Retrospective Studies Terminal Care Palliative sedation deep sedation hospice care palliative care palliative medicine prospective studies sedation systematic review *terminally ill
Psychometric Properties of Nursing Delirium Screening Scale in Patients Admitted to Intensive Care Units	Amirajam, Z. Asadi-Noran, E. Molaei, B. Adiban, V. Heidarzadeh, M. Hassanpour-Darghah, M.	Indian J Crit Care Med	2021	Delirium Intensive care Validity
Delirium researchers' perspectives of the challenges in delirium biomarker research: A qualitative study	Amgarth-Duff, I. Hosie, A. Caplan, G. A. Agar, M.	PLoS One	2021	Biomarkers/blood Biomedical Research Delirium/blood Female Humans Male Qualitative Research Research Personnel
Addition of Valerian and Lemon Balm Extract to Quetiapine Reduces Agitation in Critically Ill Patients with Delirium: A Pilot Randomized Clinical Trial	Alikiaie, B. Shahmoradi, E. Yekdaneh, A. Mousavi, S.	Indian J Crit Care Med	2021	Delirium Lemon balm Quetiapine Valerian
Spinal block and delirium in oncologic patients after laparoscopic surgery in the Trendelenburg position: A randomized controlled trial	Mitsunaga, J. K. Junior Calsavara, V. F. Onari, E. S. Arantes, V. M. Akamine, C. P. Handa, A. M. Quezada, M. M. C. Ito, F. Y. Porto, A. C. S. Giroud Joaquim, E. H. Nakamura, G.	PLoS One	2021
Perioperative Vascular Biomarker Profiling in Elective Surgery Patients Developing Postoperative Delirium: A Prospective Cohort Study	Menzenbach, J. Frede, S. Petras, J. Guttenthaler, V. Kirfel, A. Neumann, C. Mayr, A. Wittmann, M. Coburn, M. Klaschik, S. Hilbert, T.	Biomedicines	2021	Ccl2 Mcp-1 biomarker cardiac surgery elective surgery glycocalyx postoperative delirium vascular inflammation
Preliminary Study of Serum Biomarkers Associated With Delirium After Major Cardiac Surgery	McKay, T. B. Rhee, J. Colon, K. Adelsberger, K. Turco, I. Mueller, A. Qu, J. Akeju, O.	J Cardiothorac Vasc Anesth	2021	Fgf cardiac surgery cardiopulmonary bypass cognition delirium fibroblast growth factor inflammation metabolism neurodegeneration
Stratified delirium risk using prescription medication data in a state-wide cohort	McCoy, T. H., Jr. Castro, V. M. Hart, K. L. Perlis, R. H.	Gen Hosp Psychiatry	2021	Cohort study Data mining Delirium Feature engineering Pharmacovigilance Predictive modeling
Nutritional Risk at intensive care unit admission and outcomes in survivors of critical illness	Mart, M. F. Girard, T. D. Thompson, J. L. Whitten-Vile, H. Raman, R. Pandharipande, P. P. Heyland, D. K. Ely, E. W. Brummel, N. E.	Clin Nutr	2021	Activities of daily living Cognitive dysfunction Critical illness Nutrition assessment Patient discharge Quality of life
Risk Factors for Delirium Are Different in the Very Old: A Comparative One-Year Prospective Cohort Study of 5,831 Patients	Marquetand, J. Bode, L. Fuchs, S. Hildenbrand, F. Ernst, J. von Kaenel, R. Boettger, S.	Front Psychiatry	2021	comparison delirium prospective risk factors very old
Plasma interleukin-6 is a potential predictive biomarker for postoperative delirium among acute type a aortic dissection patients treated with open surgical repair	Lv, X. C. Lin, Y. Wu, Q. S. Wang, L. Hou, Y. T. Dong, Y. Chen, L. W.	J Cardiothorac Surg	2021	Adult Aged Aneurysm, Dissecting/ surgery Aortic Aneurysm/ surgery Area Under Curve Biomarkers/blood Delirium/ blood/etiology Humans Interleukin-6/ blood Male Middle Aged Postoperative Complications/blood/etiology ROC Curve Retrospective Studies Aortic dissection Inflammatory cytokines Interleukin-6 Postoperative delirium
Association of early and later depressive symptoms with functional outcome after ischemic stroke	Lopatkiewicz, A. M. Pera, J. Slowik, A. Dziedzic, T.	J Neural Transm (Vienna)	2021	Cognitive decline Delirium Depression Outcome Stroke
Development and validation of a postoperative delirium prediction model for pediatric patients: A prospective, observational, single-center study	Lin, N. Liu, K. Feng, J. Chen, R. Ying, Y. Lv, D. Zhou, Y. Xu, H.	Medicine (Baltimore)	2021	Adolescent Anesthesia, General/ adverse effects/methods Child Child, Preschool Developmental Disabilities/ epidemiology Dexmedetomidine/administration & dosage/ adverse effects Emergence Delirium/ epidemiology/etiology/prevention & control Female Humans Hypnotics and Sedatives/administration & dosage/ adverse effects Infant Infant, Newborn Logistic Models Male Prevalence Prospective Studies ROC Curve Risk Assessment/methods/statistics & numerical data Risk Factors
Patients' experiences of delirium: A systematic review and meta-summary of qualitative research	Kuusisto-Gussmann, E. Höckelmann, C. von der Lühe, V. Schmädig, R. Baltes, M. Stephan, A.	J Adv Nurs	2021	delirium nursing qualitative research systematic review
Effects of case-based confusion assessment methods for intensive care unit training on delirium knowledge and delirium assessment accuracy of intensive care units: A quasi-experimental study	Kim, Y. N. Kim, D. H.	Nurse Educ Today	2021	Critical Illness Delirium/diagnosis Hospitals, University Humans Intensive Care Units Republic of Korea Assessment Delirium Education Intensive care unit Knowledge Nursing
Bridging the Gap Between the Intensive Care Unit and the Acute Medical Care Unit	Kim, E. Kast, C. Afroz-Hossain, A. Qiu, M. Pappas, K. Sinvani, L.	Am J Crit Care	2021
Preoperative MRI brain phenotypes are related to postoperative delirium in older individuals	Kant, I. M. J. Slooter, A. J. C. Jaarsma-Coes, M. van Montfort, S. J. T. Witkamp, T. D. Pasma, W. Hendrikse, J. de Bresser, J.	Neurobiol Aging	2021	Brain phenotypes Delirium Encephalopathy Mri
Pre-Existing Psychiatric Illness Is Associated With an Increased Risk of Delirium in Patients With Acute Respiratory Distress Syndrome	Kalra, S. S. Jaber, J. Alzghoul, B. N. Hyde, R. Parikh, S. Urbine, D. Reddy, R.	J Intensive Care Med	2021	Ards acute respiratory distress syndrome anxiety delirium depression psychiatric illness
Development and internal validation of a predictive model of cognitive decline 36 months following elective surgery	Jones, R. N. Tommet, D. Steingrimsson, J. Racine, A. M. Fong, T. G. Gou, Y. Hshieh, T. T. Metzger, E. D. Schmitt, E. M. Tabloski, P. A. Travison, T. G. Vasunilashorn, S. M. Abdeen, A. Earp, B. Kunze, L. Lange, J. Vlassakov, K. Dickerson, B. C. Marcantonio	Alzheimers Dement (Amst)	2021	cognitive decline delirium machine learning model prediction post‐operative statistical learning
The performance of the Dutch Safety Management System frailty tool to predict the risk of readmission or mortality in older hospitalised cardiac patients	Jepma, P. Verweij, L. Tijssen, A. Heymans, M. W. Flierman, I. Latour, C. H. M. Peters, R. J. G. Scholte Op Reimer, W. J. M. Buurman, B. M. Ter Riet, G.	BMC Geriatr	2021	Aged Aged, 80 and over Female Frailty Geriatric Assessment Humans Male Netherlands/epidemiology Patient Readmission Prospective Studies Risk Assessment Risk Factors Safety Management Cardiovascular diseases Mortality Predictive value of tests
Outcomes of transcatheter aortic valve replacement in patients with cognitive dysfunction	Jain, V. Kalra, A. Panhwar, M. S. Bansal, A. Nowacki, A. Bhatia, K. Gupta, T. Ineman, N. L. Khan, S. U. Krishnaswamy, A. Reed, G. W. Puri, R. Kapadia, S. R. Svensson, L. G. Kanaa, N. A. Lahorra, J. A.	J Am Geriatr Soc	2021	cognitive impairment dementia outcomes transcatheter aortic valve replacement
The Importance of Delirium and Delirium Prevention in Older Adults During Lockdowns	Inouye, S. K.	JAMA	2021	Aged COVID-19/ psychology Delirium/etiology/ prevention & control Hospitalization Humans Infection Control Inpatients/psychology Physical Distancing
Association of Pain With Atrial Fibrillation and Delirium After Cardiac Surgery: A DECADE Sub-Study	Ince, I. Chiu, A. Sagir, A. Chahar, P. Lin, J. Douglas, A. Adi, A. Fang, J. Mao, G. Turan, A.	J Cardiothorac Vasc Anesth	2021	atrial fibrillation delirium pain
Higher versus lower mean arterial pressure target management in older patients having non-cardiothoracic surgery: A prospective randomized controlled trial	Hu, A. M. Qiu, Y. Zhang, P. Zhao, R. Li, S. T. Zhang, Y. X. Zheng, Z. H. Hu, B. L. Yang, Y. L. Zhang, Z. J.	J Clin Anesth	2021	Aged Anesthesia, General/adverse effects Arterial Pressure Delirium/epidemiology/etiology/prevention & control Female Humans Postoperative Complications/epidemiology/etiology/prevention & control Prospective Studies Elderly patients General anaesthesia Mean arterial pressure Postoperative delirium
Are Patients Taking Benzodiazepines at Increased Risk for Complications Following Primary Total Knee Arthroplasty?	Hernandez, N. M. Cunningham, D. J. Hinton, Z. W. Wu, C. J. Seyler, T. M.	J Arthroplasty	2021	Arthroplasty, Replacement, Knee/adverse effects Benzodiazepines/adverse effects Humans Joint Diseases Odds Ratio Postoperative Complications/chemically induced/epidemiology Reoperation Retrospective Studies Risk Factors benzodiazepines complications delirium revision total knee arthroplasty
Preoperative medication use and development of postoperative delirium and cognitive dysfunction	Heinrich, M. Nottbrock, A. Borchers, F. Mörgeli, R. Kruppa, J. Winterer, G. Slooter, A. J. C. Spies, C.	Clin Transl Sci	2021
Radiological, Chemical, and Pharmacological Cholinergic System Parameters and Neurocognitive Disorders in Older Presurgical Adults	Heinrich, M. Müller, A. Lammers-Lietz, F. Borchers, F. Mörgeli, R. Kruppa, J. Zacharias, N. Winterer, G. Slooter, A. J. C. Spies, C. D.	J Gerontol A Biol Sci Med Sci	2021	Anticholinergic medication Cholinesterase Cognition Magnetic resonance imaging
Predictors and Sequelae of Postoperative Delirium in a Geriatric Patient Population With Hip Fracture	Haynes, M. S. Alder, K. D. Toombs, C. Amakiri, I. C. Rubin, L. E. Grauer, J. N	J Am Acad Orthop Surg Glob Res Rev	2021	Postoperative Delirium Hip fracture Dementia Geriatric Preoperative dementia
Visual Analytics in Delirium Management	Hackl, W. O. Netzer, M. Nantschev, R. Schaller, M. Ammenwerth, E.	Stud Health Technol Inform	2021	Aged Cluster Analysis Data Mining Delirium Humans Delirium management data visualization patient safety
Characterizing Sleep Disruption and Delirium in Children After Cardiac Surgery: A Feasibility Study	Gregory, J. L. Brown, A. T. Kudchadkar, S. R.	Pediatr Crit Care Med	2021
One-Year Medicare Costs Associated With Delirium in Older Patients Undergoing Major Elective Surgery	Gou, R. Y. Hshieh, T. T. Marcantonio, E. R. Cooper, Z. Jones, R. N. Travison, T. G. Fong, T. G. Abdeen, A. Lange, J. Earp, B. Schmitt, E. M. Leslie, D. L. Inouye, S. K.	JAMA Surg	2021
Implementing Delirium Screening in an Intermediate Care Unit	Gaa, C. A. Akintade, B. F.	J Dr Nurs Pract	2021	confusion assessment method delirium delirium screening intermediate care unit
Malocclusion of Molar Teeth Is Associated with Activities of Daily Living Loss and Delirium in Elderly Critically Ill Older Patients	Fujinami, Y. Hifumi, T. Ono, Y. Saito, M. Okazaki, T. Shinohara, N. Akiyama, K. Kunikata, M. Inoue, S. Kotani, J. Kuroda, Y.	J Clin Med	2021	ICU prognosis frailty poor oral health
Electroencephalography of mechanically ventilated patients at high risk of delirium	Eskioglou, E. Iaquaniello, C. Alvarez, V. Rüegg, S. Schindler, K. Rossetti, A. O. Oddo, M.	Acta Neurol Scand	2021	Eeg critical care delirium
Risk Factors and Antipsychotic Usage Patterns Associated With Terminal Delirium in a Veteran Long-Term Care Hospice Population	Ellsworth, E. M. Bacigalupo, K. J. Palla, K. R. Limaye, S. S. Walkosz, M. J. Szczecinski, S. T. Suda, K. J.	Fed Pract	2021
Does cognitive decline/dementia increase Delirium risk after stroke?	Ding, G. Hua, S. Chen, J. Yang, S. Xie, R.	Psychogeriatrics	2021	Cognitive Dysfunction Delirium Dementia Humans Odds Ratio Stroke cognitive decline meta-analysis stroke.
Heterogeneity in design and analysis of ICU delirium randomized trials: a systematic review	Colantuoni, E. Koneru, M. Akhlaghi, N. Li, X. Hashem, M. D. Dinglas, V. D. Neufeld, K. J. Harhay, M. O. Needham, D. M.	Trials	2021	Adult Critical Illness Delirium/diagnosis/prevention & control Humans Intensive Care Units Randomized Controlled Trials as Topic Critically ill patients Delirium Outcome definition Randomized trials Statistical methods Systematic review
The frequency and quality of delirium documentation in discharge summaries	Chuen, V. L. Chan, A. C. H. Ma, J. Alibhai, S. M. H. Chau, V.	BMC Geriatr	2021	Delirium/diagnosis/epidemiology Documentation Hospitalization Humans Patient Discharge Retrospective Studies Delirium Discharge summary Geriatrics Quality
Using data linkage for national surveillance of clinical quality indicators for dementia care among Australian aged care users	Cations, M. Lang, C. Ward, S. A. Caughey, G. E. Crotty, M. Whitehead, C. Ahern, S. Maddison, J. Inacio, M. C.	Sci Rep	2021
Geriatric fracture centre vs usual care after proximal femur fracture in older patients: what are the benefits? Results of a large international prospective multicentre study	Blauth, M. Joeris, A. Rometsch, E. Espinoza-Rebmann, K. Wattanapanom, P. Jarayabhand, R. Poeze, M. Wong, M. K. Kwek, E. B. K. Hegeman, J. H. Perez-Uribarri, C. Guerado, E. Revak, T. J. Zohner, S. Joseph, D. Gosch, M.	BMJ Open	2021	Aged Aged, 80 and over Cohort Studies Femur Hip Fractures/surgery Humans Prospective Studies Quality of Life geriatric medicine health services administration & management hip orthopaedic & trauma surgery trauma management
Effects of dexmedetomidine on neurocognitive disturbance after elective non-cardiac surgery in senile patients: a systematic review and meta-analysis	Bi, X. Wei, J. Zhang, X.	J Int Med Res	2021	China Cognitive Dysfunction/drug therapy/prevention & control Delirium Dexmedetomidine/therapeutic use Humans Hypotension Postoperative Complications/prevention & control Anesthesiology dexmedetomidine non-cardiac surgery postoperative cognitive disturbance postoperative delirium senile
Non-pharmacological interventions for preventing delirium in hospitalised non-ICU patients (Review)	Burton JK, Craig LE, Yong SQ, Siddiqi N, Teale EA, Woodhouse R, Barugh AJ, Shepherd AM, Brunton A, Freeman SC, Sutton AJ, Quinn TJ	Cochrane Database of Systematic Reviews	2021
Incidence and risk factors for postoperative delirium after liver transplantation: a systematic review and meta-analysis	Zhou, S. Deng, F. Zhang, J. Chen, G.	Eur Rev Med Pharmacol Sci	2021
The perioperative application of continuous cerebral autoregulation monitoring for cerebral protection in elderly patients	Zhang, Y. Tan, J. Li, P. Zhang, X. Yang, Y. Liu, Y. Fu, Q. Cao, J. Mi, W. Zhang, H. Li, H.	Ann Palliat Med	2021	Aged Arterial Pressure Cerebrovascular Circulation Homeostasis Humans Male Middle Aged Oximetry Spectroscopy, Near-Infrared Cerebral autoregulation (CA) optimal mean arterial pressure (optimal MAP) regional cerebral oxygen saturation (rScO2) robotic-assisted laparoscopic radical prostatectomy (RALP)