Delirium Bibliography

Delirium Bibliography books graphicWhat is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!

How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.

Reference Information

Title
Efficacy of melatonin in decreasing the incidence of delirium in critically ill adults: a randomized controlled trial
Authors
Bandyopadhyay, A. Yaddanapudi, L. N. Saini, V. Sahni, N. Grover, S. Puri, S. Ashok, V.
Year
2024
Journal
Crit Care Sci
Abstract

OBJECTIVE: To determine whether enteral melatonin decreases the incidence of delirium in critically ill adults. METHODS: In this randomized controlled trial, adults were admitted to the intensive care unit and received either usual standard care alone (Control Group) or in combination with 3mg of enteral melatonin once a day at 9 PM (Melatonin Group). Concealment of allocation was done by serially numbered opaque sealed envelopes. The intensivist assessing delirium and the investigator performing the data analysis were blinded to the group allocation. The primary outcome was the incidence of delirium within 24 hours of the intensive care unit stay. The secondary outcomes were the incidence of delirium on Days 3 and 7, intensive care unit mortality, length of intensive care unit stay, duration of mechanical ventilation and Glasgow outcome score (at discharge). RESULTS: We included 108 patients in the final analysis, with 54 patients in each group. At 24 hours of intensive care unit stay, there was no difference in the incidence of delirium between Melatonin and Control Groups (29.6 versus 46.2%; RR = 0.6; 95%CI 0.38 – 1.05; p = 0.11). No secondary outcome showed a statistically significant difference. CONCLUSION: Enteral melatonin 3mg is not more effective at decreasing the incidence of delirium than standard care is in critically ill adults.

PMID

PMID: 38656078

Keywords

Humans
*Melatonin/administration & dosage/therapeutic use
*Delirium/prevention & control/epidemiology/drug therapy
*Critical Illness
Male
Female
Middle Aged
Incidence
*Intensive Care Units
Length of Stay
Aged
Respiration, Artificial/adverse effects
Adult

Page(s)
Issue

Search:
Total Records Found: 6050, showing 100 per page
TitleAuthorsJournalYearKeywords
Atypical presentation of COVID-19 in a frail older person Tay, H. S. Harwood, R. Age Ageing 2020

Covid-19
atypical presentation
older people
pandemic
pneumonia

ADAPT-2: A Randomized Clinical Trial to Reduce Intraoperative EEG Suppression in Older Surgical Patients Undergoing Major Noncardiac Surgery Tang, C. J. Jin, Z. Sands, L. P. Pleasants, D. Tabatabai, S. Hong, Y. Leung, J. M. Anesth Analg 2020
Dexmedetomidine with sufentanil in intravenous patient-controlled analgesia for relief from postoperative pain, inflammation and delirium after esophageal cancer surgery Tang, C. Hu, Y. Zhang, Z. Wei, Z. Wang, H. Geng, Q. Shi, S. Wang, S. Wang, J. Chai, X. Biosci Rep 2020

Dexmedetomidine
delirium
inflammatory response
patient-controlled analgesia
postoperative pain
thoracoscopic-laparoscopic esophagectomy

Cohort study into the neural correlates of postoperative delirium: the role of connectivity and slow-wave activity Tanabe, S. Mohanty, R. Lindroth, H. Casey, C. Ballweg, T. Farahbakhsh, Z. Krause, B. Prabhakaran, V. Banks, M. I. Sanders, R. D. Br J Anaesth 2020

cognitive dysfunction
connectivity
delirium
electroencephalogram
inflammation
mechanism
postoperative
slow wave activity
surgery

Preoperative circadian physical activity rhythm and postoperative delirium in cardiovascular surgery patients Tan, C. Saito, N. Miyawaki, I. Shiotani, H. Chronobiol Int 2020

Postoperative delirium
circadian rhythm
cosine
periodic regression analysis
physical activity

Real-world evidence of the safety and efficacy profile of suvorexant in elderly patients with insomnia: a sub-analysis of the post-marketing drug-use results survey in Japan Takeuchi, Y. Sano, H. Asai, Y. Miyazaki, M. Iwakura, M. Maeda, Y. Current Medical Research and Opinion 2020

hypnotic agent
suvorexant
abdominal discomfort
adult
aged
article
asthenia
attention disturbance
bipolar disorder
brain hemorrhage
clinical practice
cognitive defect
cold sweat
comorbidity
delirium
depression
diarrhea
dizziness
drug efficacy
drug eruption
drug safety
edema
face edema
female
femoral neck fracture
hallucination
hot flush
human
hypersalivation
insomnia
internal medicine
Japan
major clinical study
male
mental disease
night sweat
pollakisuria
postmarketing surveillance
pruritus
rash
schizophrenia
self evaluation
sleep disordered breathing
somnolence
subdural hematoma
suicidal ideation
visual hallucination

Electroencephalography-Guided Anesthetic Delivery for Preventing Postoperative Delirium in Adults: An Updated Meta-analysis Sun, Y. Ye, F. Wang, J. Ai, P. Wei, C. Wu, A. Xie, W. Anesth Analg 2020
Risk and Consequences of Postoperative Delirium in Cardiac Surgery Sugimura, Y. Sipahi, N. F. Mehdiani, A. Petrov, G. Awe, M. Minol, J. P. Boeken, U. Korbmacher, B. Lichtenberg, A. Dalyanoglu, H. Thorac Cardiovasc Surg 2020
Risk of Hospitalized Falls and Hip Fractures in 22,103 Older Adults Receiving Mental Health Care vs 161,603 Controls: A Large Cohort Study Stubbs, B. Perara, G. Koyanagi, A. Veronese, N. Vancampfort, D. Firth, J. Sheehan, K. De Hert, M. Stewart, R. Mueller, C. J Am Med Dir Assoc 2020

Hip fracture
falls dementia
mental illness
schizophrenia
substance use disorder

Pharmacist-driven discontinuation of antipsychotics for ICU delirium: A quasi-experimental study Stuart, M. M. Smith, Z. R. Payter, K. A. Martz, C. R. To, L. Swiderek, J. L. Coba, V. E. Peters, M. A. JACCP Journal of the American College of Clinical Pharmacy 2020

adult
article
controlled study
coronary care unit
delirium
demography
drug therapy
drug withdrawal
female
gender
hospital discharge
human
incidence
length of stay
major clinical study
male
outcome assessment
pharmacist
psychosis
QT prolongation
QTc interval
quasi experimental study
rank sum test
retrospective study
neuroleptic agent

Interventions to prevent in-hospital falls in older people with cognitive impairment for further research: a mixed studies review Stockwell-Smith, G. Adeleye, A. Chaboyer, W. Cooke, M. Phelan, M. Todd, J. A. Grealish, L. J Clin Nurs 2020

In-hospital fall
cognitive impairment
delirium
dementia
prevention

Early Identification of Delirium in Intensive Care Unit Patients: Improving the Quality of Care Spiegelberg, J. Song, H. Pun, B. Webb, P. Boehm, L. M. Crit Care Nurse 2020
Efficacy and Safety of Dexmedetomidine for Prolonged Sedation in the PICU: A Prospective Multicenter Study (PROSDEX) Sperotto, F. Mondardini, M. C. Dell'Oste, C. Vitale, F. Ferrario, S. Lapi, M. Ferrero, F. Dusio, M. P. Rossetti, E. Daverio, M. Amigoni, A. Pediatr Crit Care Med 2020
Restricted versus liberal intraoperative benzodiazepine use in cardiac anaesthesia for reducing delirium (B-Free Pilot): a pilot, multicentre, randomised, cluster crossover trial Spence, J. Belley-Côté, E. Jacobsohn, E. Lee, S. F. Whitlock, R. Bangdiwala, S. Syed, S. Sarkaria, A. MacIsaac, S. Lengyel, A. Long, S. Um, K. McIntyre, W. F. Kavosh, M. Fast, I. Arora, R. Lamy, A. Connolly, S. Devereaux, P. J. Br J Anaesth 2020

awareness
benzodiazepines
cardiac anaesthesia
delirium
pilot study
pragmatic
randomised cluster crossover

Thoracic continuous spinal anesthesia for high-risk comorbid older patients undergoing major abdominal surgery: one-year experience of an Italian geriatric hospital Spannella, F. Giulietti, F. Damiani, E. Faloia, L. Stronati, M. Venezia, A. Vincenzi, P. Castellani, D. Boccoli, G. Dellabella, M. Giampieri, M. Sarzani, R. Starnari, R. Minerva Anestesiol 2020
Identification of distinct clinical phenotypes in mechanically ventilated patients with acute brain dysfunction using cluster analysis Souza-Dantas, V. C. Dal-Pizzol, F. Tomasi, C. D. Spector, N. Soares, M. Bozza, F. A. Póvoa, P. Salluh, J. I. F. Medicine (Baltimore) 2020

Apache
Academic Medical Centers
Aged
Biomarkers
C-Reactive Protein/analysis
Cluster Analysis
Coma/ epidemiology
Comorbidity
Delirium/ epidemiology
Female
Humans
Hypnotics and Sedatives/administration & dosage
Intensive Care Units/ statistics & numerical data
Male
Middle Aged
Phenotype
Prospective Studies
Respiration, Artificial/ statistics & numerical data
Risk Assessment
Risk Factors
Sepsis/epidemiology
Socioeconomic Factors
Time Factors

Validation of a multidisciplinary care protocol for critically ill patients with delirium Souza, T. L. Azzolin, K. O. Souza, E. N. Revista gaucha de enfermagem 2020

adult
agitation
analgesia
article
clinical outcome
consensus
content validity
critically ill patient
delirium
human
intensive care unit
mobilization
outcome assessment
sedation
sleep
validation process

Hospital Costs and Reimbursement Model for a Geriatric Emergency Department Southerland, L. T. Savage, E. L. Muska Duff, K. Caterino, J. M. Bergados, T. R. Hunold, K. M. Finnegan, G. I. Archual, G. Acad Emerg Med 2020
Natural light exposure and delirium in ICU: does the dark side cloud everything? Sonneville, R. Smonig, R. Dupuis, C. Bouadma, L. de Montmollin, E. Timsit, J. F. Annals of Intensive Care 2020

sedative agent
adult respiratory distress syndrome
anxiety
critically ill patient
depression
hallucination
hospital admission
human
hypoxemia
incidence
intensive care
intensive care psychosis
intensive care unit
letter
light exposure
phenotype
priority journal
risk reduction
sepsis
survivor

Neurocognitive Complications after Ventricular Neuroendoscopy: A Systematic Review Soleman, J. Guzman, R. Behavioural Neurology 2020

rigid endoscope
arachnoid cyst
brain damage
brain fornix
brain third ventricle
brain ventricle
brain ventricle tumor
choroid plexus tumor
clinical outcome
cognition assessment
cognitive defect
colloid cyst
confusion
depressive psychosis
emotional disorder
executive function
follow up
human
hydrocephalus
memory disorder
mental deterioration
mental disease
morbidity
neuroendoscopy
neurological complication
neuropsychological test
organic psychosyndrome
personality disorder
postoperative cognitive dysfunction
postoperative complication
postoperative period
preoperative period
review
systematic review
ventricular neuroendoscopy

Investigation of ward fidelity to a multicomponent delirium prevention intervention during a multicentre, pragmatic, cluster randomised, controlled feasibility trial Smith, J. Green, J. Siddiqi, N. Inouye, S. K. Collinson, M. Farrin, A. Young, J. Age Ageing 2020

delirium prevention
intervention fidelity
multi-component intervention
older people

Clinical outcomes associated with sedation and analgesia in patients supported with venoarterial extracorporeal membrane oxygenation Skelton, P. A. Lillyblad, M. P. Eckman, P. M. Samara, M. A. Williams, D. M. Wilson, K. J. Stanberry, L. I. Hryniewicz, K. M. Int J Artif Organs 2020

Extracorporeal membrane oxygenation
analgesics
sedation
sedatives

Are Antipsychotics Helpful for Preventing or Treating Delirium? Singu, S. Koneru, M. Robinson, K. A. Neufeld, K. J. Oh, E. S. Wilson, L. M. Needham, D. M. Balagani, A. Aldabain, L. Nikooie, R. Fick, D. M. J Gerontol Nurs 2020
Family caregiver's experience of caring for an older adult with delirium: A systematic review Shrestha, P. Fick, D. M. Int J Older People Nurs 2020

delirium
delirium superimposed on dementia
experience
family caregivers
older adults
systematic review

Dexmedetomidine in the prevention of postoperative delirium in elderly patients following non-cardiac surgery: A systematic review and meta-analysis Shen, Q. H. Li, H. F. Zhou, X. Y. Yuan, X. Z. Clin Exp Pharmacol Physiol 2020

dexmedetomidine
non-cardiac surgery
postoperative delirium

Relation of serum melatonin levels to postoperative delirium in older patients undergoing major abdominal surgery Shen, Q. H. Li, H. F. Zhou, X. Y. Lu, Y. P. Yuan, X. Z. J Int Med Res 2020

Postoperative delirium
abdominal surgery
anesthesia
cognitive status
melatonin
older patient

Characteristics and Outcomes of Dementia Patients Who Receive Inpatient Palliative Care Consultation Sharda, N. Zietlow, K. Wong, S. Kuchibhatla, M. Johnson, K. S. J Am Geriatr Soc 2020

dementia
inpatient
palliative care

Low Frontal Alpha Power Is Associated With the Propensity for Burst Suppression: An Electroencephalogram Phenotype for a "Vulnerable Brain" Shao, Y. R. Kahali, P. Houle, T. T. Deng, H. Colvin, C. Dickerson, B. C. Brown, E. N. Purdon, P. L. Anesth Analg 2020
Dynamics of cerebral oxygenation during rapid ventricular pacing and its impact on outcome in transfemoral transcatheter aortic valve implantation Seppelt, P. C. Mas-Peiro, S. De Rosa, R. Murray, I. M. Arsalan, M. Holzer, L. Lotz, G. Meybohm, P. Zacharowski, K. Walther, T. Zeiher, A. M. Fichtlscherer, S. Vasa-Nicotera, M. Catheter Cardiovasc Interv 2020

Nirs
Tavi
aortic stenosis
delirium
stroke

Haemodynamic changes and emergence delirium in children undergoing isoflurane general anaesthesia for dental treatments: effect of propofol administration Selvi-Kuvvetli, S. Turan, B. S. Bayrak, G. D. Noyan, A. Pediatric Dental Journal 2020

propofol
anesthesia induction
article
body temperature
child
childhood disease
dental patient
dental procedure
emergence agitation
extubation
female
general anesthesia
heart rate
hemodynamics
human
intubation
major clinical study
male
oxygen saturation
priority journal
retrospective study
single drug dose

Anxiety symptoms are quantitatively and qualitatively different in dementia with Lewy bodies than in Alzheimer's disease in the years preceding clinical diagnosis Segers, K. Benoit, F. Meyts, J. M. Surquin, M. Psychogeriatrics 2020

Alzheimerʼs disease
Lewy body disease
anxiety
dementia
dementia with Lewy bodies

Evaluation of Sedation Outcomes Following Increased Dexmedetomidine Use in the ICU Schuler, B. R. Kovacevic, M. P. Dube, K. M. Szumita, P. M. DeGrado, J. R. Crit Care Explor 2020

benzodiazepines
critical care
delirium
dexmedetomidine
mechanical ventilation
sedation

Effect of Flumazenil on Hypoactive Delirium in the ICU: A Double-Blind, Placebo-Controlled Pilot Study Schomer, K. J. Duby, J. J. Firestone, R. L. Louie, E. L. Sebat, C. M. Love, D. M. Cocanour, C. S. Albertson, T. E. Crit Care Explor 2020

benzodiazepine
benzodiazepine antagonist
critical care
delirium
flumazenil
hypoactive delirium

Neuropsychiatric adverse events of chloroquine: a real-world pharmacovigilance study using the FDA Adverse Event Reporting System (FAERS) database Sato, K. Mano, T. Iwata, A. Toda, T. Biosci Trends 2020

Adverse Drug Reaction Reporting Systems
Aged
Betacoronavirus/isolation & purification
Chloroquine/administration & dosage/ adverse effects
Databases, Factual
Female
Humans
Male
Mental Disorders/ chemically induced
Middle Aged
Neurotoxicity Syndromes/ etiology
Pharmacovigilance
Retrospective Studies
United States
United States Food and Drug Administration
Covid-19
Faers
adverse events
chloroquine
real-world data

Prospective Study of Factors Associated With Postoperative Delirium After Urgent Abdominal Surgery Sánchez Acedo, P. Eguaras Córdoba, I. Zazpe Ripa, C. Herrera Cabezón, J. Tarifa Castilla, A. Cir Esp 2020

Ancianos
Cirugía abdominal
Cirugía urgente
Delirium
Postoperative complications
Síndrome confusional agudo
Urgent abdominal surgery

Prospective Study of Factors Associated With Postoperative Delirium After Urgent Abdominal Surgery Sánchez Acedo, P. Eguaras Córdoba, I. Zazpe Ripa, C. Herrera Cabezón, J. Tarifa Castilla, A. Cir Esp 2020

Ancianos
Cirugía abdominal
Cirugía urgente
Delirium
Postoperative complications
Síndrome confusional agudo
Urgent abdominal surgery

Non-pharmacological approaches in the prevention of delirium Salvi, F. Young, J. Lucarelli, M. Aquilano, A. Luzi, R. Dell’Aquila, G. Cherubini, A. European Geriatric Medicine 2020

psychotropic agent
clinical practice
delirium
geriatric patient
hospitalization
human
outcome assessment
phototherapy
priority journal
review
surgical patient

Natriuretic Peptides as a Prognostic Marker for Delirium in Cardiac Surgery-A Pilot Study Saller, T. Peterss, S. Scheiermann, P. Eser-Valeri, D. Ehler, J. Bruegger, D. Chappell, D. Kofler, O. Hagl, C. Hofmann-Kiefer, K. Medicina (Kaunas) 2020

biomarker
cardiac surgery
delirium
natriuretic peptide
off-pump surgery

Prospective Evaluation of Delirium in Geriatric Patients Undergoing Emergency General Surgery Saljuqi, A. T. Hanna, K. Asmar, S. Tang, A. Zeeshan, M. Gries, L. Ditillo, M. Kulvatunyou, N. Castanon, L. Joseph, B. J Am Coll Surg 2020
Effect of moderate hypothermic circulatory arrest on neurological outcomes in elderly patients undergoing replacement of the thoracic aorta Salem, M. Friedrich, C. Thiem, A. Salem, M. A. Puehler, T. Rusch, R. Berndt, R. Cremer, J. Haneya, A. Egypt Heart J 2020

Aging
Delirium
Genome-wide DNA methylation
Immune response
Inflammatory response

Epigenetics of neuroinflammation: Immune response, inflammatory response and cholinergic synaptic involvement evidenced by genome-wide DNA methylation analysis of delirious inpatients Saito, T. Toda, H. Duncan, G. N. Jellison, S. S. Yu, T. Klisares, M. J. Daniel, S. Andreasen, A. J. Leyden, L. R. Hellman, M. M. Shinozaki, E. Lee, S. Yoshino, A. Cho, H. R. Shinozaki, G. J Psychiatr Res 2020

Aging
Delirium
Genome-wide DNA methylation
Immune response
Inflammatory response

Major surgery induces acute changes in measured DNA methylation associated with immune response pathways Sadahiro, R. Knight, B. James, F. Hannon, E. Charity, J. Daniels, I. R. Burrage, J. Knox, O. Crawford, B. Smart, N. J. Mill, J. Sci Rep 2020
Basic geriatric principles for colorectal surgeons: How to optimize assessment and care of older patients in the perioperative period Rostoft, S. Hamaker, M. E. Eur J Surg Oncol 2020

Cognition
Colorectal cancer
Frailty
Functional status
Geriatric assessment
Preoperative evaluation

The association of delirium severity with patient and health system outcomes in hospitalised patients: a systematic review Rosgen, B. K. Krewulak, K. D. Stelfox, H. T. Ely, E. W. Davidson, J. E. Fiest, K. M. Age Ageing 2020

delirium
hospital
older people
outcomes
severity

Reporting of Outcomes and Outcome Measures in Studies of Interventions to Prevent and/or Treat Delirium in the Critically Ill: A Systematic Review Rose, L. Agar, M. Burry, L. Campbell, N. Clarke, M. Lee, J. Marshall, J. Siddiqi, N. Page, V. Crit Care Med 2020
Abdominal aortic aneurysm patients remain at risk for delirium on the surgical ward after intensive care unit dismissal Roijers, J. P. Spillenaar Bilgen, R. Hopmans, C. J. Mulder, P. G. Buimer, M. G. Ho, G. H. de Groot, H. G. Veen, E. J. Besselink-Lobanova, A. van der Meer, N. J. van der Laan, L. Minerva Anestesiol 2020
Psychiatric and neuropsychiatric presentations associated with severe coronavirus infections: a systematic review and meta-analysis with comparison to the COVID-19 pandemic Rogers, J. P. Chesney, E. Oliver, D. Pollak, T. A. McGuire, P. Fusar-Poli, P. Zandi, M. S. Lewis, G. David, A. S. Lancet Psychiatry 2020

Coronavirus Infections/ complications
Fatigue/ etiology
Humans
Mental Disorders/ etiology
Nervous System Diseases/ etiology
Pandemics
Pneumonia, Viral/ complications
Severe Acute Respiratory Syndrome/ complications

Characterisation and outcome of neuropsychiatric symptoms in patients with anti-NMDAR encephalitis Restrepo-Martinez, M. Ramirez-Bermudez, J. Bayliss, L. Espinola-Nadurille, M. Acta Neuropsychiatr 2020

anti-N-methyl-D-aspartate receptor encephalitis
diagnosis
differential
neuropsychiatry
psychoneuroimmunology

Delirious mania as a frequent and recognizable neuropsychiatric syndrome in patients with anti-NMDAR encephalitis Restrepo-Martinez, M. Ramirez-Bermudez, J. Bayliss, L. Espinola-Nadurille, M. Gen Hosp Psychiatry 2020

Anti-NMDA receptor encephalitis
Autoimmune encephalitis
Catatonia
Delirium
Mania

Diffusion tensor imaging and resting-state functional magnetic resonance imaging in patients with delirium in intensive care unit Renjie, S. Ganjun, S. Peng, X. Haizhen, D. Tianxi, Z. Yuanlan, L. Mo, L. Xiaoyun, F. Zhonghua Wei Zhong Bing Ji Jiu Yi Xue 2020

sedative agent
anterior cingulate
article
brain damage
brain function
brain region
caudate nucleus
cerebellum
clinical article
controlled study
corpus callosum
corpus striatum
delirium
diffusion tensor imaging
drug use
educational status
fractional anisotropy
frontal lobe
functional magnetic resonance imaging
hospital admission
human
inferior frontal gyrus
insula
intensive care psychosis
intensive care unit
left hippocampus
mean diffusivity
mesencephalon
middle frontal gyrus
morphology
parietal lobe
pons
right hippocampus
superior frontal gyrus
temporal lobe

Mortality of gerontopsychiatric inpatients in Graz, Austria—a retrospective case-control study Rásky, É Stolz, E. Jagsch, C. Neuropsychiatrie 2020

article
Austria
controlled study
female
gerontopsychiatry
human
major clinical study
male
mortality
retrospective study

Barriers to rehabilitation after critical illness: a survey of multidisciplinary healthcare professionals caring for ICU survivors in an acute care hospital Rai, S. Anthony, L. Needham, D. M. Georgousopoulou, E. N. Sudheer, B. Brown, R. Mitchell, I. van Haren, F. Aust Crit Care 2020

Intensive care
Post–intensive care syndrome
Rehabilitation
Survivorship

Older Patients with Alzheimer's Disease-Related Cortical Atrophy Who Develop Post-Operative Delirium May Be at Increased Risk of Long-Term Cognitive Decline after Surgery Racine, A. M. Touroutoglou, A. Abrantes, T. Wong, B. Fong, T. G. Cavallari, M. Travison, T. G. Gou, Y. Marcantonio, E. R. Alsop, D. C. Jones, R. N. Inouye, S. K. Dickerson, B. C. Journal of Alzheimer's Disease 2020

aged
aging
Alzheimer disease
article
brain atrophy
brain cortex
cognition
cognitive defect
cohort analysis
cortical thickness (brain)
disease association
elective surgery
female
follow up
Hopkins verbal learning test
human
major clinical study
male
neuroimaging
nuclear magnetic resonance imaging
postoperative delirium
preoperative evaluation
priority journal
risk factor
surgical patient
trail making test
verbal learning

Psychiatric comorbidities in cancer patients: acute interventions by the psychiatric consultation liaison service Quante, A. Schulz, K. Fissler, M. Wiener Medizinische Wochenschrift 2020

adult
article
cancer patient
comorbidity
consultation
controlled study
delirium
demography
depression
drug therapy
female
general hospital
hospital patient
human
lung cancer
major clinical study
male
psychiatric diagnosis
psychiatrist
psychotherapy
retrospective study
antidepressant agent

Delirium is associated with higher mortality in transcatheter aortic valve replacement: systemic review and meta-analysis Prasitlumkum, N. Mekritthikrai, R. Kewcharoen, J. Kanitsoraphan, C. Mao, M. A. Cheungpasitporn, W. Cardiovasc Interv Ther 2020

Delirium
Meta-analysis
Mortality
Systematic reviews
Transcatheter aortic valve replacement

A novel geriatric assessment tool that predicts postoperative complications in older adults with cancer Pollock, Y. Chan, C. L. Hall, K. Englesbe, M. Diehl, K. M. Min, L. J Geriatr Oncol 2020

Functional decline
Geriatric assessment
Geriatric complications
Postoperative complications

Modifiable factors associated with postoperative delirium after hip fracture repair: An age-stratified retrospective cohort study Poeran, J. Cozowicz, C. Zubizarreta, N. Weinstein, S. M. Deiner, S. G. Leipzig, R. M. Friedman, J. I. Liu, J. Mazumdar, M. Memtsoudis, S. G. Eur J Anaesthesiol 2020
Downregulation of synapse-associated protein expression and loss of homeostatic microglial control in cerebrospinal fluid of infectious patients with delirium and patients with Alzheimer's disease Peters van Ton, A. M. Verbeek, M. M. Alkema, W. Pickkers, P. Abdo, W. F. Brain Behav Immun 2020

Alzheimer’s disease
Delirium
Infection
cerebrospinal fluid
homeostatic microglial control
synapse

Documentation of acute change in mental status in nursing homes highlights opportunity to augment infection surveillance criteria Penna, A. R. Sancken, C. L. Stone, N. D. Eure, T. R. Bamberg, W. Barney, G. Barter, D. Carswell, S. Clogher, P. Dumyati, G. Felsen, C. B. Frank, L. Godine, D. Johnston, H. Kainer, M. A. Li, L. Lynfield, R. Mahoehney, J. P. Nadle, J. Pierce, R. Ray, S. M. Infect Control Hosp Epidemiol 2020
Effect of Dexmedetomidine on Cardiac Surgery-Associated Acute Kidney Injury: A Meta-Analysis With Trial Sequential Analysis of Randomized Controlled Trials Peng, K. Li, D. Applegate, R. L., 2nd Lubarsky, D. A. Ji, F. H. Liu, H. J Cardiothorac Vasc Anesth 2020

acute kidney injury
cardiac surgery
dexmedetomidine
meta-analysis
trial sequential analysis

Electroencephalogram Burst-suppression during Cardiopulmonary Bypass in Elderly Patients Mediates Postoperative Delirium Pedemonte, J. C. Plummer, G. S. Chamadia, S. Locascio, J. J. Hahm, E. Ethridge, B. Gitlin, J. Ibala, R. Mekonnen, J. Colon, K. M. Westover, M. B. D'Alessandro, D. A. Tolis, G. Houle, T. Shelton, K. T. Qu, J. Akeju, O. Anesthesiology 2020
Evaluating delirium outcomes among older adults in the surgical intensive care unit Pavone, K. J. Jablonski, J. Junker, P. Cacchione, P. Z. Compton, P. Polomano, R. C. Heart Lung 2020

Critical care
Delirium
Elderly
Intensive care
Length of stay
Mortality
Older adult
Readmissions
Sicu

Association between continuous deep sedation and survival time in terminally ill cancer patients Park, S. J. Ahn, H. K. Ahn, H. Y. Han, K. T. Hwang, I. C. Support Care Cancer 2020

Continuous deep sedation
Hospice
Palliative care
Palliative sedation
Sedative
Survival

Liver Transplant Patients with High Preoperative Serum Bilirubin Levels Are at Increased Risk of Postoperative Delirium: A Retrospective Study Park, K. H. Son, H. J. Choi, Y. J. Park, G. H. Lee, Y. S. Park, J. Y. Ri, H. S. Shim, J. R. J Clin Med 2020

bilirubin
complication
liver transplantation
postoperative delirium

Smoking-cessation pharmacotherapy for patients with stroke and TIA: Systematic review Parikh, N. S. Salehi Omran, S. Kamel, H. Elkind, M. S. V. Willey, J. Z. J Clin Neurosci 2020

Cerebrovascular Disease
Pharmacology
Secondary Prevention
Smoking Cessation
Stroke
Transient Ischemic Attack (TIA)

A prospective cohort study on predictors of mortality of delirium in an emergency observational unit Pal, S. Sharma, N. Singh, S. M. Bhutungru, S. Pannu, A. K. QJM 2020

Acute confusional state
Cam-icu
Drs-r-98
Delirium
Emergency department
Intensive care unit
Mortality
Prevalence
Screening

Preoperative Anxiety and Depression Increases the Incidence of Delirium After Coronary Artery Bypass Graft Surgery Pakrad, F. Pakrad, E. Darvishi, N. Poorolajal, J. J Perianesth Nurs 2020

anxiety
coronary artery bypass
delirium
depression
postoperative

Association between fluid overload and delirium/coma in mechanically ventilated patients Ouchi, A. Sakuramoto, H. Hoshino, H. Matsuishi, Y. Sakaguchi, T. Enomoto, Y. Hoshino, T. Shimojo, N. Inoue, Y. Acute Med Surg 2020

Brain dysfunction
delirium
fluid
fluid overload
intensive care

Hallucinations after Cardiac Surgery: A Prospective Observational Study Ottens, T. H. Sommer, I. E. C. Begemann, M. J. Schutte, M. Cramer, M. J. Suyker, W. J. Van Dijk, D. Slooter, A. J. C. Medicina (Kaunas) 2020

cardiothoracic surgery
delirium
hallucinations
neuropsychiatric outcomes

Preoperative sepsis is a predictive factor for 30-day mortality after major lower limb amputation among patients with arteriosclerosis obliterans and diabetes Otsuka, T. Arai, M. Sugimura, K. Sakai, M. Nishizawa, Y. Suzuki, Y. Okamoto, H. Kuroiwa, M. J Orthop Sci 2020
Patient-related and anesthesia-dependent determinants for postoperative delirium after oral and maxillofacial surgery. Results from a register-based case-control study Ortner, F. Eberl, M. Otto, S. Wang, B. Schauberger, G. Hofmann-Kiefer, K. Saller, T. J Stomatol Oral Maxillofac Surg 2020

Dementia
Dentoalveolar surgery
Oral and maxillofacial surgery
Pacu
Postoperative delirium
Tooth extraction

Investigation of Free-Flap Transfer Reconstruction in Elderly Patients and Oral Intake Function Onoda, S. Kinoshita, M. Ariyoshi, Y. J Craniofac Surg 2020
Delirium: a missing piece in the COVID-19 pandemic puzzle O'Hanlon, S. Inouye, S. K. Age Ageing 2020

Covid-19
delirium
older people

Effects of Ramelteon on the Prevention of Postoperative Delirium in Older Patients Undergoing Orthopedic Surgery: The RECOVER Randomized Controlled Trial Oh, E. S. Leoutsakos, J. M. Rosenberg, P. B. Pletnikova, A. M. Khanuja, H. S. Sterling, R. S. Oni, J. K. Sieber, F. E. Fedarko, N. S. Akhlaghi, N. Neufeld, K. J. Am J Geriatr Psychiatry 2020

Delirium
melatonin receptor agonist
orthopedic surgery
ramelteon

A roadmap to advance delirium research: Recommendations from the NIDUS Scientific Think Tank Oh, E. S. Akeju, O. Avidan, M. S. Cunningham, C. Hayden, K. M. Jones, R. N. Khachaturian, A. S. Khan, B. A. Marcantonio, E. R. Needham, D. M. Neufeld, K. J. Rose, L. Spence, J. Tieges, Z. Vlisides, P. Inouye, S. K. Alzheimers Dement 2020

biomarkers
definition
delirium
dementia
diagnosis
measurement
pathophysiology
prevention
public health campaign
treatment

Association between a prognostic nutritional index less than 50 and the risk of medical complications after adult spinal deformity surgery Oe, S. Yamato, Y. Hasegawa, T. Yoshida, G. Kobayashi, S. Yasuda, T. Banno, T. Arima, H. Mihara, Y. Ushirozako, H. Yamada, T. Ide, K. Watanabe, Y. Matsuyama, Y. J Neurosurg Spine 2020

ASD = adult spinal deformity
AUC = area under the curve
BMI = body mass index
C7-CSVL = C7 plumb line to the central sacral vertical line
CCI = Charlson Comorbidity Index
CL = cervical lordosis
DVT = deep venous thrombosis
LL = lumbar lordosis
PE = pulmonary embolism
PI = pelvic incidence
PNI = prognostic nutritional index
PT = pelvic tilt
ROC = receiver operating characteristic
SSI = surgical site infection
SVA = sagittal vertical axis
TK = thoracic kyphosis
TS = T1 slope
adult spinal deformity
delirium
malnutrition
medical complications
nutritional status
prognostic nutritional index

Communication with patients in post-traumatic confusional state: perception of rehabilitation staff Nielsen, A. I. Power, E. Jensen, L. R. Brain Injury 2020

comprehension
confusion
content analysis
cross-sectional study
health personnel attitude
human
interpersonal communication
medical staff
neurorehabilitation
open-ended questionnaire
professional-patient relationship
rehabilitation center
review
traumatic brain injury
verbal communication

Singapore SPICE: Sedation practices in intensive care evaluation in Singapore - A prospective cohort study of the public healthcare system Ng, S. Y. Phua, J. Wong, Y. L. Kalyanasundaram, G. Mukhopadhyay, A. Lim, D. Chia, N. Ho, B. C. H. Bailey, M. J. Shehabi, Y. Ti, L. K. Singapore Medical Journal 2020

dexmedetomidine
diazepam
fentanyl
haloperidol
ketamine
midazolam
morphine
propofol
anesthesia level
artificial ventilation
clinical trial
cohort analysis
controlled study
critically ill patient
delirium
endotracheal intubation
hospital discharge
hospital mortality
human
incidence
intensive care
length of stay
major clinical study
mortality
multicenter study
neurologic disease
outcome assessment
practice guideline
prospective study
public health
review
Richmond Agitation Sedation Scale
sedation
Singapore

Association of obstructive sleep apnea and postoperative cardiac complications: A systematic review and meta-analysis with trial sequential analysis Ng, K. T. Lee, Z. X. Ang, E. Teoh, W. Y. Wang, C. Y. J Clin Anesth 2020

Cardiac complications
Meta-analysis
Mortality
Obstructive sleep apnea
Oximetry
Sleep study

Long-term mortality in very old patients with cancer admitted to intensive care unit: A retrospective cohort study Nassar Junior, A. P. Trevisani, M. D. S. Bettim, B. B. Caruso, P. J Geriatr Oncol 2020

Aged 80 and over
Cancer
Critical care
Decision making
Mortality

Functional Outcomes of Frail Patients after Cardiac Surgery: An Observational Study Nakano, M. Nomura, Y. Suffredini, G. Bush, B. Tian, J. Yamaguchi, A. Walston, J. Hasan, R. Mandal, K. Schena, S. Hogue, C. W. Brown, C. H. Anesthesia and Analgesia 2020

adult
article
complication
controlled study
daily life activity
delirium
EuroSCORE
female
frailty
functional status
gender
heart surgery
hospitalization
human
major clinical study
male
observational study
prevalence
propensity score
race
risk assessment
surgery
surgical risk

Development of a clinical score, PANDA, to predict delirium in stroke care unit Nakamizo, T. Kanda, T. Kudo, Y. Sugawara, E. Hashimoto, E. Okazaki, A. Usuda, M. Nagai, T. Hara, H. Johkura, K. J Neurol Sci 2020

Area under curve
Clinical decision rules
Clinical nursing research
Delirium
Sensitivity and specificity
Sleep deprivations
Stroke care unit

Impact of Tobacco Smoking on Outcomes after Posterior Decompression Surgery in Patients with Cervical Spondylotic Myelopathy: A Retrospective Multicenter Study Nagoshi, N. Kono, H. Tsuji, O. Aoyama, R. Fujiyoshi, K. Shiono, Y. Ishikawa, M. Daimon, K. Hosogane, N. Takeuchi, A. Okada, E. Fujita, N. Yagi, M. Nakamura, M. Matsumoto, M. Watanabe, K. Ishii, K. Yamane, J. Clinical Spine Surgery 2020

adult
article
attention
case control study
cervical spondylotic myelopathy
clinical evaluation
complication
controlled study
decompression surgery
demography
ex-smoker
female
follow up
hematoma
human
Japan
Japanese Orthopaedic Association score
laminectomy
laminoplasty
liquorrhea
major clinical study
male
multicenter study
neck pain
non-smoker
paralysis
peroperative complication
postoperative delirium
preoperative evaluation
retrospective study
smoking cessation
surgery
surgical infection
visual analog scale

Role of omega-3 fatty acids in the prevention of delirium in mechanically ventilated patients Naghibi, T. Shafigh, N. Mazloomzadeh, S. Journal of Research in Medical Sciences 2020

IRCT2015095536N5
haloperidol
omega 3 fatty acid
adult
agitation
APACHE
article
artificial ventilation
clinical outcome
confusion
Confusion Assessment Method
controlled study
delirium
double blind procedure
female
Glasgow coma scale
human
intensive care unit
length of stay
major clinical study
male
mental disease assessment
middle aged
mortality
outcome assessment
randomized controlled trial
Richmond Agitation Sedation Scale

Brain BOLD MRI O(2) and CO(2) stress testing: implications for perioperative neurocognitive disorder following surgery Mutch, W. A. C. El-Gabalawy, R. Ryner, L. Puig, J. Essig, M. Kilborn, K. Fidler, K. Graham, M. R. Crit Care 2020

Anesthesia
Bold
Co2
Cognitive dysfunction
Critical care
Delirium
Mri
Mechanical ventilation
O2

Off-label use of quetiapine in nursing homes: Does medical specialty of prescribing physicians play a role? Müller, L. Noseda, R. Bertoli, R. Bissig, M. Ceschi, A. British Journal of Clinical Pharmacology 2020

quetiapine
anxiety disorder
delirium
dementia
depression
human
insomnia
letter
major clinical study
medical specialist
nursing home
physician
prescription
priority journal
Switzerland

Multidisciplinary quality improvement programme for older patients admitted to a vascular surgery ward() Mudge, A. M. McRae, P. Donovan, P. J. Reade, M. C. Intern Med J 2020

delirium
functional decline
length of hospital stay
patient care team
vascular surgery

Cross-cultural adaptation and validation of the 3D-CAM Chinese version in surgical ICU patients Mu, D. L. Ding, P. P. Zhou, S. Z. Liu, M. J. Sun, X. Y. Li, X. Y. Wang, D. X. BMC Psychiatry 2020

3d-cam
Chinese version, validation, Chinese
Delirium
Diagnosis
Screening tool

Thiamine for Prevention of Postoperative Delirium in Patients Undergoing Gastrointestinal Surgery: A Randomized Clinical Trial Moslemi, R. Khalili, H. Mohammadi, M. Mehrabi, Z. Mohebbi, N. J Res Pharm Pract 2020

Delirium
Thiamine
gastrointestinal surgery

How successful are we in relieving terminal dyspnea in cancer patients? A real-world multicenter prospective observational study Mori, M. Morita, T. Matsuda, Y. Yamada, H. Kaneishi, K. Matsumoto, Y. Matsuo, N. Odagiri, T. Aruga, E. Watanabe, H. Tatara, R. Sakurai, H. Kimura, A. Katayama, H. Suga, A. Nishi, T. Shirado, A. N. Watanabe, T. Kuchiba, A. Yamaguchi, T. Iwase, S. Supportive Care in Cancer 2020
Understanding Factors Associated With Psychomotor Subtypes of Delirium in Older Inpatients With Dementia Morandi, A. Zambon, A. Di Santo, S. G. Mazzone, A. Cherubini, A. Mossello, E. Bo, M. Marengoni, A. Bellelli, G. Journal of the American Medical Directors Association 2020

intravenous catheter
urinary catheter
antibiotic agent
antilipemic agent
antithrombocytic agent
cholinesterase inhibitor
hydroxymethylglutaryl coenzyme A reductase inhibitor
memantine
neuroleptic agent
aged
article
cross-sectional study
delirium
dementia
female
hospitalization
human
Italy
major clinical study
male
medical record
prescription
prevalence
very elderly

Infection in older adults: a qualitative study of patient experience Moore, A. McKelvie, S. Glogowska, M. Lasserson, D. Hayward, G. Br J Gen Pract 2020

aged
frail elderly
infection
qualitative research

Aripiprazole for prevention of delirium in the neurosurgical intensive care unit: a double-blind, randomized, placebo-controlled study Mokhtari, M. Farasatinasab, M. Jafarpour Machian, M. Yaseri, M. Ghorbani, M. Ramak Hashemi, S. M. Nikoobakht, M. Golchin, N. Mohammadi, G. Sistanizad, M. Eur J Clin Pharmacol 2020

Aripiprazole
Delirium
Delirium prevention
Icu

Potentially Inappropriate Medications in a Psychogeriatric Inpatient Ward: An Audit Based on Beers Criteria Moebs, I. Abeln, E. Siefert, A. Barak, Y. Neurology and Therapy 2020

adult
aged
anxiety
article
attention deficit disorder
bipolar disorder
clinical audit
clinical decision making
delirium
depression
drug dependence
female
generalized anxiety disorder
gerontopsychiatry
human
major clinical study
male
medication compliance
mental disease
personality disorder
posttraumatic stress disorder
prescription
priority journal
psychiatry
psychosis
retrospective study
schizophrenia
very elderly

An 11-year review of hip fracture hospitalisations, health outcomes, and predictors of access to in-hospital rehabilitation for adults ≥ 65 years living with and without dementia: a population-based cohort study Mitchell, R. Draper, B. Brodaty, H. Close, J. Ting, H. P. Lystad, R. Harris, I. Harvey, L. Sherrington, C. Cameron, I. D. Braithwaite, J. Osteoporos Int 2020

Aged care
Dementia
Frailty
Hip fracture
Rehabilitation

Evaluation of a co-produced delirium awareness programme for undergraduate nursing students in Northern Ireland: a pre-test/post-test study Mitchell, G. McVeigh, C. Carlisle, S. Brown-Wilson, C. BMC Nurs 2020

Co-design
Co-production
Delirium
Nurse education
Nursing
Nursing student

Perioperative dexmedetomidine and postoperative delirium in non-cardiac surgery: a meta-analysis Ming, S. Zhang, X. Gong, Z. Xie, Y. Xie, Y. Ann Palliat Med 2020

Dexmedetomidine
meta-analysis
postoperative delirium
surgery

Cholinesterases and Anticholinergic Medications in Postoperative Pediatric Delirium Meyburg, J. Ritsert, M. L. Traube, C. Plaschke, K. von Haken, R. Pediatr Crit Care Med 2020
Comparison of novel tools with traditional cognitive tests in detecting delirium in elderly medical patients Meagher, D. J. O'Connell, H. Leonard, M. Williams, O. Awan, F. Exton, C. Tenorio, M. O'Connor, M. Dunne, C. P. Cullen, W. McFarland, J. Adamis, D. World J Psychiatry 2020

Assessment
Attention
Delirium
Dementia
Letter and Shape Drawing test
Lighthouse test
Phenomenology
Vigilance
Visuospatial function

A systematic review and meta-analysis of the accuracy of the clock drawing test (CDT) in the identification of delirium in older hospitalised patients Meagher, D. Williams, O. A. O'Connell, H. Leonard, M. Cullen, W. Dunne, C. P. Mulligan, O. Adamis, D. Aging & mental health 2020

adult
aged
article
Cinahl
clock drawing test
cognitive defect
diagnosis
diagnostic test accuracy study
Embase
female
hospital patient
human
male
Medline
meta analysis
Mini Mental State Examination
Preferred Reporting Items for Systematic Reviews and Meta-Analyses
PsycINFO
Scopus
sensitivity and specificity
software
systematic review