What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Exercise for acutely hospitalised older medical patients
- Authors
- Hartley, P. Keating, J. L. Jeffs, K. J. Raymond, M. J. Smith, T. O
- Year
- 2022
- Journal
- Cochrane Database Syst Rev
- Abstract
BACKGROUND: Approximately 30% of hospitalised older adults experience hospital-associated functional decline. Exercise interventions that promote in-hospital activity may prevent deconditioning and thereby maintain physical function during hospitalisation. This is an update of a Cochrane Review first published in 2007. OBJECTIVES: To evaluate the benefits and harms of exercise interventions for acutely hospitalised older medical inpatients on functional ability, quality of life (QoL), participant global assessment of success and adverse events compared to usual care or a sham-control intervention. SEARCH METHODS: We used standard, extensive Cochrane search methods. The latest search date was May 2021. SELECTION CRITERIA: We included randomised or quasi-randomised controlled trials evaluating an in-hospital exercise intervention in people aged 65 years or older admitted to hospital with a general medical condition. We excluded people admitted for elective reasons or surgery. DATA COLLECTION AND ANALYSIS: We used standard Cochrane methods. Our major outcomes were 1. independence with activities of daily living; 2. functional mobility; 3. new incidence of delirium during hospitalisation; 4. QoL; 5. number of falls during hospitalisation; 6. medical deterioration during hospitalisation and 7. participant global assessment of success. Our minor outcomes were 8. death during hospitalisation; 9. musculoskeletal injuries during hospitalisation; 10. hospital length of stay; 11. new institutionalisation at hospital discharge; 12. hospital readmission and 13. walking performance. We used GRADE to assess certainty of evidence for each major outcome. We categorised exercise interventions as: rehabilitation-related activities (interventions designed to increase physical activity or functional recovery, but did not follow a specified exercise protocol); structured exercise (interventions that included an exercise intervention protocol but did not include progressive resistance training); and progressive resistance exercise (interventions that included an element of progressive resistance training). MAIN RESULTS: We included 24 studies (nine rehabilitation-related activity interventions, six structured exercise interventions and nine progressive resistance exercise interventions) with 7511 participants. All studies compared exercise interventions to usual care; two studies, in addition to usual care, used sham interventions. Mean ages ranged from 73 to 88 years, and 58% of participants were women. Several studies were at high risk of bias. The most common domain assessed at high risk of bias was measurement of the outcome, and five studies (21%) were at high risk of bias arising from the randomisation process. Exercise may have no clinically important effect on independence in activities of daily living at discharge from hospital compared to controls (16 studies, 5174 participants; low-certainty evidence). Five studies used the Barthel Index (scale: 0 to 100, higher scores representing greater independence). Mean scores at discharge in the control groups ranged from 42 to 96 points, and independence in activities of daily living was 1.8 points better (0.43 worse to 4.12 better) with exercise compared to controls. The minimally clinical important difference (MCID) is estimated to be 11 points. We are uncertain regarding the effect of exercise on functional mobility at discharge from the hospital compared to controls (8 studies, 2369 participants; very low-certainty evidence). Three studies used the Short Physical Performance Battery (SPPB) (scale: 0 to 12, higher scores representing better function) to measure functional mobility. Mean scores at discharge in the control groups ranged from 3.7 to 4.9 points on the SPPB, and the estimated effect of the exercise interventions was 0.78 points better (0.02 worse to 1.57 better). A change of 1 point on the SPPB represents an MCID. We are uncertain regarding the effect of exercise on the incidence of delirium during hospitalisation compared to controls (7 trials, 2088 participants; very low-certainty evidence). The incidence of delirium during hospitalisation was 88/1091 (81 per 1000) in the control group compared with 70/997 (73 per 1000; range 47 to 114) in the exercise group (RR 0.90, 95% CI 0.58 to 1.41). Exercise interventions may result in a small clinically unimportant improvement in QoL at discharge from the hospital compared to controls (4 studies, 875 participants; low-certainty evidence). Mean QoL on the EuroQol 5 Dimensions (EQ-5D) visual analogue scale (VAS) (scale: 0 to 100, higher scores representing better QoL) ranged between 48.9 and 64.7 in the control group at discharge from the hospital, and QoL was 6.04 points better (0.9 better to 11.18 better) with exercise. A change of 10 points on the EQ-5D VAS represents an MCID. No studies measured participant global assessment of success. Exercise interventions did not affect the risk of falls during hospitalisation (moderate-certainty evidence). The incidence of falls was 31/899 (34 per 1000) in the control group compared with 31/888 (34 per 1000; range 20 to 57) in the exercise group (RR 0.99, 95% CI 0.59 to 1.65). We are uncertain regarding the effect of exercise on the incidence of medical deterioration during hospitalisation (very low-certainty evidence). The incidence of medical deterioration in the control group was 101/1417 (71 per 1000) compared with 96/1313 (73 per 1000; range 44 to 120) in the exercise group (RR 1.02, 95% CI 0.62 to 1.68). Subgroup analyses by different intervention categories and by the use of a sham intervention were not meaningfully different from the main analyses. AUTHORS’ CONCLUSIONS: Exercise may make little difference to independence in activities of daily living or QoL, but probably does not result in more falls in older medical inpatients. We are uncertain about the effect of exercise on functional mobility, incidence of delirium and medical deterioration. Certainty of evidence was limited by risk of bias and inconsistency. Future primary research on the effect of exercise on acute hospitalisation could focus on more consistent and uniform reporting of participant’s characteristics including their baseline level of functional ability, as well as exercise dose, intensity and adherence that may provide an insight into the reasons for the observed inconsistencies in findings.
- PMID
- Keywords
Aged
Aged, 80 and over
Female
Humans
Male
Activities of Daily Living
*Delirium/epidemiology
Exercise
*Quality of Life
- Page(s)
- Volume
- Issue
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| Validation of the 3-minute diagnostic interview for CAM-defined Delirium in Chinese older adults | Ji, M. Wang, J. Yang, X. Huang, Y. Xiao, Y. Wu, Y. | Geriatr Nurs | 2020 |
3d-cam |
| Diagnostic Test Accuracy of the 4AT for Delirium Detection: A Systematic Review and Meta-Analysis | Jeong, E. Park, J. Lee, J. | Int J Environ Res Public Health | 2020 |
4at |
| Development and Evaluation of Clinical Practice Guideline for Delirium in Long-Term Care | Jeong, E. Park, J. Chang, S. O. | Int J Environ Res Public Health | 2020 |
aged |
| Risk prediction of delirium in hospitalized patients using machine learning: An implementation and prospective evaluation study | Jauk, S. Kramer, D. Großauer, B. Rienmüller, S. Avian, A. Berghold, A. Leodolter, W. Schulz, S. | J Am Med Inform Assoc | 2020 |
Machine learning |
| Objectively measured sleep fragmentation is associated with incident delirium in older hospitalized patients: Analysis of data collected from an randomized controlled trial | Jaiswal, S. J. Kang, D. Y. Wineinger, N. E. Owens, R. L. | J Sleep Res | 2020 |
actigraphy |
| Incidence and predictors of delirium on the intensive care unit after acute myocardial infarction, insight from a retrospective registry | Jäckel, M. Zotzmann, V. Wengenmayer, T. Duerschmied, D. Biever, P. M. Spieler, D. von Zur Mühlen, C. Stachon, P. Bode, C. Staudacher, D. L. | Catheter Cardiovasc Interv | 2020 |
NuDesc |
| Real-World Preventive Effects of Suvorexant in Intensive Care Delirium: A Retrospective Cohort Study | Izuhara, M. Izuhara, H. K. Tsuchie, K. Araki, T. Ito, T. Sato, K. Miura, S. Otsuki, K. Nagahama, M. Hayashida, M. Hashioka, S. Wake, R. Kimura, T. Tsumoto, S. Saito, Y. Inagaki, M. | J Clin Psychiatry | 2020 |
Adolescent |
| Prognostic Value of Delirium in Patients With Acute Heart Failure in the Intensive Care Unit | Iwata, E. Kondo, T. Kato, T. Okumura, T. Nishiyama, I. Kazama, S. Ishihara, T. Kondo, S. Hiraiwa, H. Tsuda, T. Ito, M. Aoyama, M. Tanimura, D. Awaji, Y. Unno, K. Murohara, T. | Canadian Journal of Cardiology | 2020 |
acute heart failure |
| Postoperative delirium after reconstructive surgery for oral tumor: a retrospective clinical study | Ishibashi-Kanno, N. Takaoka, S. Nagai, H. Okubo-Sato, M. Fukuzawa, S. Uchida, F. Yamagata, K. Yanagawa, T. Bukawa, H. | Int J Oral Maxillofac Surg | 2020 |
Delirium |
| Vitamin D status and complications, readmissions, and mortality after hip fracture | Ingstad, F. Solberg, L. B. Nordsletten, L. Thorsby, P. M. Hestnes, I. Frihagen, F. | Osteoporos Int | 2020 |
Delirium |
| Multi-disciplinary and pharmacological interventions to reduce post-operative delirium in elderly patients: A systematic review and meta-analysis | Igwe, E. O. Nealon, J. Mohammed, M. Hickey, B. Chou, K. R. Chen, J. K. Traynor, V. | Journal of Clinical Anesthesia | 2020 |
bupivacaine |
| Preoperative serum biomarkers in the prediction of postoperative delirium following abdominal surgery | Ida, M. Takeshita, Y. Kawaguchi, M. | Geriatr Gerontol Int | 2020 |
biomarker |
| Rotigotine patch prescription in inpatients with Parkinson's disease: evaluating prescription accuracy, delirium and end-of-life use | Ibrahim, H. Woodward, Z. Pooley, J. Richfield, E. W. | Age Ageing | 2020 |
Parkinson’s disease |
| Effect of Cognitive Prehabilitation on the Incidence of Postoperative Delirium among Older Adults Undergoing Major Noncardiac Surgery: The Neurobics Randomized Clinical Trial | Humeidan, M. L. Reyes, J. P. C. Mavarez-Martinez, A. Roeth, C. Nguyen, C. M. Sheridan, E. Zuleta-Alarcon, A. Otey, A. Abdel-Rasoul, M. Bergese, S. D. | JAMA Surgery | 2020 |
aged |
| Delirium in intensive care: violence, loss and humanity | Hume, V. J. | Med Humanit | 2020 |
arts in health/arts and health |
| Neuroleptic strategies for terminal agitation in patients with cancer and delirium at an acute palliative care unit: a single-centre, double-blind, parallel-group, randomised trial | Hui, D. De La Rosa, A. Wilson, A. Nguyen, T. Wu, J. Delgado-Guay, M. Azhar, A. Arthur, J. Epner, D. Haider, A. De La Cruz, M. Heung, Y. Tanco, K. Dalal, S. Reddy, A. Williams, J. Amin, S. Armstrong, T. S. Breitbart, W. Bruera, E. | Lancet Oncol | 2020 |
Aged |
| Incidence and risk factors of delirium after percutaneous coronary intervention in individuals hospitalised for acute myocardial infarction: protocol for a systematic review and meta-analysis | Huang, K. Lu, J. Zhu, Y. Cheng, T. Du, D. Qian, X. Pan, H. Wang, X. Yang, H. Lou, S. | BMJ Open | 2020 |
coronary intervention |
| Dexmedetomidine for prevention of postoperative delirium in older adults undergoing oesophagectomy with total intravenous anaesthesia: A double-blind, randomised clinical trial | Hu, J. Zhu, M. Gao, Z. Zhao, S. Feng, X. Chen, J. Zhang, Y. Maze, M. | European journal of anaesthesiology | 2020 |
aged |
| Antipsychotic prescribing to people with dementia during COVID-19 | Howard, R. Burns, A. Schneider, L. | The Lancet Neurology | 2020 |
neuroleptic agent |
| A phase II study of ramelteon for the prevention of postoperative delirium in elderly patients undergoing gastrectomy | Honda, S. Furukawa, K. Makuuchi, R. Irino, T. Tokunaga, M. Tanizawa, Y. Bando, E. Kawamura, T. Shinsato, K. Matsumoto, T. Terashima, M. | Surg Today | 2020 |
Elderly patients |
| Preventative effects of ramelteon against postoperative delirium after elective liver resection | Hokuto, D. Nomi, T. Yoshikawa, T. Matsuo, Y. Kamitani, N. Sho, M. | PLoS One | 2020 |
Adult |
| Dexmedetomidine: A Novel Strategy for Patients with Intractable Pain, Opioid-Induced Hyperalgesia, or Delirium at the End of Life | Hofherr, M. L. Abrahm, J. L. Rickerson, E. | J Palliat Med | 2020 |
delirium |
| Diagnostic Performance of Delirium Assessment Tools in Critically Ill Patients: A Systematic Review and Meta-Analysis | Ho, M. H. Montgomery, A. Traynor, V. Chang, C. C. Kuo, K. N. Chang, H. C. R. Chen, K. H. | Worldviews on evidence-based nursing | 2020 |
adult |
| Alpha2 agonist dexmedetomidine may reduce duration of delirium in critically ill adults | Hill, J. Sange, C. Clegg, A. | Evidence-based nursing | 2020 |
adult |
| Delirium and encephalopathy in severe COVID-19: a cohort analysis of ICU patients | Helms, J. Kremer, S. Merdji, H. Schenck, M. Severac, F. Clere-Jehl, R. Studer, A. Radosavljevic, M. Kummerlen, C. Monnier, A. Boulay, C. Fafi-Kremer, S. Castelain, V. Ohana, M. Anheim, M. Schneider, F. Meziani, F. | Crit Care | 2020 |
Aged |
| Detecting Delirium: A Systematic Review of Identification Instruments for Non-ICU Settings | Helfand, B. K. I. D'Aquila, M. L. Tabloski, P. Erickson, K. Yue, J. Fong, T. G. Hshieh, T. T. Metzger, E. D. Schmitt, E. M. Boudreaux, E. D. Inouye, S. K. Jones, R. N. | J Am Geriatr Soc | 2020 |
delirium |
| Radiological, Chemical and Pharmacological Cholinergic System Parameters and Neurocognitive Disorders in Older Pre-Surgical Adults | Heinrich, M. Müller, A. Lammers-Lietz, F. Borchers, F. Mörgeli, R. Kruppa, J. Zacharias, N. Winterer, G. Slooter, A. J. C. Spies, C. D. | J Gerontol A Biol Sci Med Sci | 2020 |
Anticholinergic Medication |
| Dexmedetomidine for the prevention of postoperative delirium in patients after intracranial operation for brain tumours (DEPOD study): a study protocol and statistical plan for a multicentre randomised controlled trial | He, X. Cheng, K. M. Zhang, L. Gu, H. Qu, X. Xu, Y. Ma, P. Zhou, J. X. | BMJ Open | 2020 |
adult intensive & critical care |
| Association between increased neutrophil-to-lymphocyte ratio and postoperative delirium in elderly patients with total hip arthroplasty for hip fracture | He, R. Wang, F. Shen, H. Zeng, Y. LijuanZhang | BMC Psychiatry | 2020 |
Elderly patients |
| The accuracy of delirium assessment by cardiologists treating heart failure inpatients: a single center retrospective survey | Hayashi, A. Kobayashi, S. Matsui, K. Akaho, R. Nishimura, K. | Biopsychosoc Med | 2020 |
Consultation-liaison psychiatry |
| Rates of delirium associated with calcium channel blockers compared to diuretics, renin-angiotensin system agents and beta-blockers: An electronic health records network study | Harrison, P. J. Luciano, S. Colbourne, L. | J Psychopharmacol | 2020 |
Delirium |
| Managing delirium in terminally ill patients: perspective of palliative care nurse specialists | Harris, C. Spiller, J. Finucane, A. | Br J Community Nurs | 2020 |
Clinical nurse specialists |
| Metabolomic and Lipidomic Profiling of Preoperative CSF in Elderly Hip Fracture Patients With Postoperative Delirium | Han, Y. Zhang, W. Liu, J. Song, Y. Liu, T. Li, Z. Wang, X. Yang, N. Li, Y. Han, D. Mi, X. Zhou, Y. Li, M. Guo, X. Zhong, L. Wang, G. Yuan, Y. | Front Aging Neurosci | 2020 |
cerebrospinal fluid |
| Increased Association With Malnutrition and Malnourishment in Older Adults Admitted With Hip Fractures Who Have Cognitive Impairment and Delirium, as Assessed by 4AT | Han, T. S. Lisk, R. Osmani, A. Sharmin, R. El Gammel, S. Yeong, K. Fluck, D. Fry, C. H. | Nutr Clin Pract | 2020 |
cognitive dysfunction |
| Delirium During Recovery in Patients With Severe COVID-19: Two Case Reports | Han, D. Wang, C. Feng, X. Wu, J. | Front Med (Lausanne) | 2020 |
Covid-19 |
| Mannitol Is Associated with Less Postoperative Delirium after Aortic Valve Surgery in Patients Treated with Bretschneider Cardioplegia | Hamiko, M. Charitos, E. I. Velten, M. Hilbert, T. Putensen, C. Treede, H. Duerr, G. D. | Thoracic and Cardiovascular Surgeon | 2020 |
adult |
| Comparison of the prevalence and associated factors of hyperactive delirium in advanced cancer patients between inpatient palliative care and palliative home care | Hamano, J. Mori, M. Ozawa, T. Sasaki, J. Kawahara, M. Nakamura, A. Hashimoto, K. Hisajima, K. Koga, T. Goto, K. Fukumoto, K. Morimoto, Y. Goshima, M. Sekimoto, G. Baba, M. Oya, K. Matsunuma, R. Azuma, Y. Imai, K. Morita, T. Shinjo, T. | Cancer Med | 2020 |
advanced cancer patients |
| Treatment of delirium in palliative patients - role of neuroleptics | Hainsch-Müller, I. Aulmann, C. Djukic, I. | Internistische Praxis | 2020 |
neuroleptic agent |
| Identifying Delirium Early after Stroke: A New Prediction Tool for the Intensive Care Unit | Haight, T. N. Marsh, E. B. | J Stroke Cerebrovasc Dis | 2020 |
Adult |
| Socioeconomic Factors and Intensive Care Unit-Related Cognitive Impairment | Haddad, D. N. Mart, M. F. Wang, L. Lindsell, C. J. Raman, R. Nordness, M. F. Sharp, K. W. Pandharipande, P. P. Girard, T. D. Ely, E. W. Patel, M. B. | Ann Surg | 2020 |
Aged |
| Opioid use is Associated with ICU Delirium in Mechanically Ventilated Children | Gupta, N. Woolley, A. Talathi, S. Davlyatov, G. Colston, C. Hayes, L. | J Crit Care Med (Targu Mures) | 2020 |
intensive care unit |
| A two-year multicenter point prevalence study of older patients with hip fractures admitted to rehabilitation units in Italy | Guerzoni, V. Lanzoni, A. Pozzi, C. Paci, M. Gatti, R. Benedetti, M. G. Gentile, S. Trabucchi, M. Bellelli, G. Morandi, A. | Eur Geriatr Med | 2020 |
Delirium |
| Preoperative Cognitive Impairment and Postoperative Delirium Predict Decline in Activities of Daily Living after Cardiac Surgery-A Prospective, Observational Cohort Study | Guenther, U. Hoffmann, F. Dewald, O. Malek, R. Brimmers, K. Theuerkauf, N. Putensen, C. Popp, J. | Geriatrics (Basel) | 2020 |
activity of daily living |
| Risk Factors for Delirium and Cognitive Decline Following Coronary Artery Bypass Grafting Surgery: A Systematic Review and Meta-Analysis | Greaves, D. Psaltis, P. J. Davis, D. H. J. Ross, T. J. Ghezzi, E. S. Lampit, A. Smith, A. E. Keage, H. A. D. | J Am Heart Assoc | 2020 |
cognitive decline |
| Prevalence and risk factors of delirium in the intensive care unit: An observational study | Gravante, F. Giannarelli, D. Pucci, A. Gagliardi, A. M. Mitello, L. Montagna, A. Latina, R. | Nurs Crit Care | 2020 |
delirium |
| Health Care Professionals' Reports of Cancer Pain Cues Among Older People With Delirium: A Qualitative-Quantitative Content Analysis | Graham, C. A. Chaves, G. Harrison, R. Gauthier, L. R. Nissim, R. Zimmermann, C. Chan, V. Rodin, G. Stevens, B. Gagliese, L. | J Pain Symptom Manage | 2020 |
Cancer pain |
| Benzodiazepinics and the treatment of delirium: a literature review | Gonçalves, O. H. P. Pellissari, G. M. Paiva, H. S. | Rev Assoc Med Bras (1992) | 2020 |
Benzodiazepines/therapeutic use |
| Analysis of Delirium from the Dynamic Symptoms Model: A Literature Review | Gómez Tovar, L. O. Henao Castaño, A. M. | Critical Care Nursing Quarterly | 2020 |
conceptual framework |
| Association of delirium with long-term cognitive decline: A meta-analysis | Goldberg, T. E. Chen, C. Wang, Y. Jung, E. Swanson, A. Ing, C. Garcia, P. S. Whittington, R. A. Moitra, V. | JAMA Neurology | 2020 |
article |
| Functional and cognitive decline in older delirious adults after an emergency department visit | Giroux, M. Émond, M. Nadeau, A. Boucher, V. Carmichael, P. H. Voyer, P. Pelletier, M. Gouin, É Daoust, R. Berthelot, S. Lamontagne, M. E. Morin, M. Lemire, S. Sirois, M. J. | Age Ageing | 2020 |
cognitive decline |
| The prevalence rates and sequelae of delirium at age older than 90 years | Gehrke, S. Bode, L. Seiler, A. Ernst, J. von Känel, R. Boettger, S. | Palliat Support Care | 2020 |
Delirium |
| Complications of LVAD utilization in older adults | Gazda, A. J. Kwak, M. J. Akkanti, B. Nathan, S. Kumar, S. de Armas, I. S. Baer, P. Patel, B. Kar, B. Gregoric, I. D. | Heart and Lung | 2020 |
aged |
| Consolidated framework for advancing implementation science for the implementation process and adherence assessment of a non-pharmacological delirium prevention program | Garrido, M. A. Alvarez, E. A. Ponce, D. P. Salech, F. Tobar, D. I. Tobar, E. A. | Int J Geriatr Psychiatry | 2020 |
Cfir |
| Delirium and Adverse Outcomes in Hospitalized Patients with COVID-19 | Garcez, F. B. Aliberti, M. J. R. Poco, P. C. E. Hiratsuka, M. Takahashi, S. D. F. Coelho, V. A. Salotto, D. B. Moreira, M. L. V. Jacob-Filho, W. Avelino-Silva, T. J. | Journal of the American Geriatrics Society | 2020 |
mechanical ventilator |
| The Effects of Melatonin Supplementation on Sleep Quality and Assessment of the Serum Melatonin in ICU Patients: A Randomized Controlled Trial | Gandolfi, J. V. Di Bernardo, A. P. A. Chanes, D. A. V. Martin, D. F. Joles, V. B. Amendola, C. P. Sanches, L. C. Ciorlia, G. L. Lobo, S. M. | Critical care medicine | 2020 |
adult |
| Atypical presentation of COVID-19 in hospitalised older adults | Gan, J. M. Kho, J. Akhunbay-Fudge, M. Choo, H. M. Wright, M. Batt, F. Mandal, A. K. J. Chauhan, R. Missouris, C. G. | Ir J Med Sci | 2020 |
Atypical symptoms |
| Delirium in elderly patients: Prospective prevalence across hospital services | Fuchs, S. Bode, L. Ernst, J. Marquetand, J. von Känel, R. Böttger, S. | Gen Hosp Psychiatry | 2020 |
>65 years |
| Ascertainment of delirium status using natural language processing from electronic health records | Fu, S. Lopes, G. S. Pagali, S. R. Thorsteinsdottir, B. LeBrasseur, N. K. Wen, A. Liu, H. Rocca, W. A. Olson, J. E. St Sauver, J. Sohn, S. | J Gerontol A Biol Sci Med Sci | 2020 |
confusion assessment method |
| A Multi-Phase Quality Improvement Initiative for the Treatment of Active Delirium in Older Persons | Friedman, J. I. Li, L. Kirpalani, S. Zhong, X. Freeman, R. Cheng, Y. T. Alfonso, F. L. McAlpine, G. Vakil, A. Macon, B. Francaviglia, P. Cassara, M. LoPachin, V. Reina, K. Davis, K. Reich, D. Craven, C. K. Mazumdar, M. Siu, A. L. | J Am Geriatr Soc | 2020 |
Confusion Assessment Method |
| Delirium diagnostic tool-provisional (DDT-Pro) scores in delirium, subsyndromal delirium and no delirium | Franco, J. G. Trzepacz, P. T. Sepúlveda, E. Ocampo, M. V. Velásquez-Tirado, J. D. Zaraza, D. R. Restrepo, C. Giraldo, A. M. Serna, P. A. Zuluaga, A. López, C. | Gen Hosp Psychiatry | 2020 |
Cluster analysis |
| A multimodal sevoflurane-based sedation regimen in combination with targeted temperature management in post-cardiac arrest patients reduces the incidence of delirium: An observational propensity score-matched study | Foudraine, N. A. Algargoush, A. van Osch, F. H. Bos, A. T. | Resuscitation | 2020 |
Cardiac arrest |
| Association of Plasma Neurofilament Light with Postoperative Delirium | Fong, T. G. Vasunilashorn, S. M. Ngo, L. Libermann, T. A. Dillon, S. T. Schmitt, E. M. Pascual-Leone, A. Arnold, S. E. Jones, R. N. Marcantonio, E. R. Inouye, S. K. | Ann Neurol | 2020 |
Aged |
| Course and Recognition of Poststroke Delirium: A Prospective Noninferiority Trial of Delirium Screening Tools | Fleischmann, R. Warwas, S. Andrasch, T. Kunz, R. Witt, C. Mengel, A. von Sarnowski, B. | Stroke | 2020 |
delirium |
| The collateral history: an overlooked core clinical skill | Fitzpatrick, D. Doyle, K. Finn, G. Gallagher, P. | Eur Geriatr Med | 2020 |
Clinical training |
| Management of delirium superimposed on dementia in a dementia service | FitzGerald, J. Yan, M. Bandecar, A. Ratnasabapathy, V. Rubinsztein, J. Hatfield, C. Ruhi, S. | Progress in Neurology and Psychiatry | 2020 |
adult |
| Partnering With Family Members to Detect Delirium in Critically Ill Patients | Fiest, K. M. Krewulak, K. D. Ely, E. W. Davidson, J. E. Ismail, Z. Sept, B. G. Stelfox, H. T. | Crit Care Med | 2020 |
adult |
| The correlation of intraoperative hypotension and postoperative cognitive impairment: a meta-analysis of randomized controlled trials | Feng, X. Hu, J. Hua, F. Zhang, J. Zhang, L. Xu, G. | BMC Anesthesiol | 2020 |
Intraoperative hypotension |
| The effect of joints range of motion exercises on delirium prevention in patients admitted to intensive care units | Farzammanesh, A. Jahani, S. Rashidi, M. Maraghi, E. Ravanbakhsh, M. | International Journal of Pharmaceutical and Phytopharmacological Research | 2020 |
IRCT20180114038362N1 |
| Sleep and Delirium in Older Adults | Farasat, S. Dorsch, J. J. Pearce, A. K. Moore, A. A. Martin, J. L. Malhotra, A. Kamdar, B. B. | Curr Sleep Med Rep | 2020 |
Acetylcholine |
| Association between use of angiotensin-converting enzyme inhibitors or angiotensin receptor blockers and postoperative delirium | Farag, E. Farag, E. Liang, C. Liang, C. Mascha, E. J. Mascha, E. J. Argalious, M. Y. Ezell, J. Maheshwari, K. Esa, W. A. S. Troianos, C. A. Sessler, D. I. | Anesthesiology | 2020 |
adult |
| Delirium in cardiology: An old problem, a new emergency | Falsini, G. Romanelli, S. Insana, L. Frongillo, D. Grotti, S. Angioli, P. Ducci, K. Liistro, F. Calchetti, B. Rossi, R. Bolognese, L. | Giornale Italiano di Cardiologia | 2020 |
attitude to illness |
| Surveying work-as-done in post-operative delirium risk factors collection and diagnosis monitoring | Falegnami, A. Patriarca, R. Costantino, F. Di Gravio, G. Bilotta, F. | Appl Ergon | 2020 |
RiskSOAP |
| Psychiatric disorders, delirium and mortality in patients referred for consultation in a burn center: A four-year retrospective study | Erdoğan, E. Delibaş, D. H. | Medical Journal of Bakirkoy | 2020 |
antidepressant agent |
| Delirium in Older People with COVID-19: Clinical Scenario and Literature Review | Emmerton, D. Abdelhafiz, A. | SN Compr Clin Med | 2020 |
Covid-19 |
| "It should not be that difficult to manage a condition that is so frequent": A qualitative study on hospital nurses' experience of delirium guidelines | Emme, C. | J Clin Nurs | 2020 |
Adult |
| Where should patients with or at risk of delirium be treated in an acute care system? Comparing the rates of delirium in patients receiving usual care versus alternative care: a systematic review and meta-analysis | Ekeozor, C. U. Jeyaruban, D. Lasserson, D. | Int J Clin Pract | 2020 |
Acute care |
| Effect of General Versus Spinal Anesthesia on Postoperative Delirium and Early Cognitive Dysfunction in Elderly Patients | Ehsani, R. Djalali Motlagh, S. Zaman, B. Sehat Kashani, S. Ghodraty, M. R. | Anesth Pain Med | 2020 |
Delirium |
| Anticholinergic Drug Burden and Delirium: A Systematic Review | Egberts, A. Moreno-Gonzalez, R. Alan, H. Ziere, G. Mattace-Raso, F. U. S. | Journal of the American Medical Directors Association | 2020 |
adult |
| Antipsychotics and Lorazepam During Delirium: Are We Harming Older Patients? A Real-Life Data Study | Egberts, A. Alan, H. Ziere, G. Mattace-Raso, F. U. S. | Drugs and Aging | 2020 |
acutely ill patient |
| Delirium in Internal Medicine Departments in a Tertiary Hospital in Israel: Occurrence, Detection Rates, Risk Factors, and Outcomes | Efraim, N. T. Zikrin, E. Shacham, D. Katz, D. Makulin, E. Barski, L. Zeller, L. Bartal, C. Freud, T. Lebedinski, S. Press, Y. | Front Med (Lausanne) | 2020 |
delirium |
| Development and validation of an aetiology in delirium diagnostic support tool | Eeles, E. Huang, L. Dakin, L. Ling, C. Dunn, E. Fraser, J. Dissanayaka, N. N. | Age Ageing | 2020 |
aetiology |
| Association of Geriatric Events With Perioperative Outcomes After Elective Inpatient Surgery | Dworsky, J. Q. Shellito, A. D. Childers, C. P. Copeland, T. P. Maggard-Gibbons, M. Tan, H. J. Saliba, D. Russell, M. M. | J Surg Res | 2020 |
Elderly |
| Is there an association between subjective sleep quality and daily delirium occurrence in critically ill adults? A post hoc analysis of a randomised controlled trial | Duprey, M. S. Devlin, J. W. Skrobik, Y. | BMJ Open Respir Res | 2020 |
clinical epidemiology |
| Approaches to Optimize Medication Data Analysis in Clinical Cohort Studies | Duprey, M. S. Devlin, J. W. Briesacher, B. A. Travison, T. G. Griffith, J. L. Inouye, S. K. | J Am Geriatr Soc | 2020 |
delirium |
| Delirium definition influences prediction of functional survival in patients one-year postcardiac surgery | Dubiel, C. Hiebert, B. M. Stammers, A. N. Sanjanwala, R. M. Tangri, N. Singal, R. K. Manji, R. A. Rudolph, J. L. Arora, R. C. | J Thorac Cardiovasc Surg | 2020 |
cardiac surgery |
| Prevalence and outcome of delirium among acute general medical inpatients in Cape Town, South Africa | Du Plooy, N. Day, C. Manning, K. Abdullah, F. James, K. Grace, L. Vorajee, N. April, C. Peter, J. Peter, J. Raubenheimer, P. J. | South African Medical Journal | 2020 |
indwelling urinary catheter |
| Delirium Post-Stroke-Influence on Post-Stroke Dementia (Research Study-Part of the PROPOLIS Study) | Droś, J. Kowalska, K. Pasińska, P. Szyper-Maciejowska, A. Gorzkowska, A. Klimkowicz-Mrowiec, A. | J Clin Med | 2020 |
cognitive impairment |
| Providing Evidence-Based Care, Day and Night: A Quality Improvement Initiative to Improve Intensive Care Unit Patient Sleep Quality | Douglas, S. L. Hobbs, H. A. Sibley, S. R. Digby, G. C. | J Intensive Care Med | 2020 |
critical care |
| An Implementation-Effectiveness Study of a Perioperative Delirium Prevention Initiative for Older Adults | Donovan, A. L. Braehler, M. R. Robinowitz, D. L. Lazar, A. A. Finlayson, E. Rogers, S. Douglas, V. C. Whitlock, E. L. | Anesth Analg | 2020 |
Aged |
| Effectiveness of a multidisciplinary comprehensive intervention model based on the Hospital Elderly Life Program to prevent delirium in patients with severe acute pancreatitis | Dong, Z. Song, J. Ge, M. Lin, C. Zhang, J. Chen, J. Wu, Y. | Ann Palliat Med | 2020 |
Pancreatitis |
| Does Preoperative Comprehensive Geriatric Assessment and Frailty Predict Postoperative Complications? | Dogrul, R. T. Dogrul, A. B. Konan, A. Caglar, O. Sumer, F. Caliskan, H. Kizilarslanoglu, M. C. Kilic, M. K. Balci, C. Arik, G. Aycicek, G. S. Ozsurekci, C. Halil, M. Cankurtaran, M. Yavuz, B. B. | World journal of surgery | 2020 |
aged |
| Preoperative Acute Pain Is Associated with Postoperative Delirium | Ding, X. Gao, X. Chen, Q. Jiang, X. Li, Y. Xu, J. Qin, G. Lu, S. Huang, D. | Pain Med | 2020 |
C-Reactive Protein |
| Effects of electroencephalography and regional cerebral oxygen saturation monitoring on perioperative neurocognitive disorders: a systematic review and meta-analysis | Ding, L. Chen, D. X. Li, Q. | BMC Anesthesiol | 2020 |
Electroencephalography |
| The Addition of Intravenous Propofol and Ketorolac to a Sevoflurane Anesthetic Lessens Emergence Agitation in Children Having Bilateral Myringotomy with Tympanostomy Tube Insertion: A Prospective Observational Study | d'Eon, B. Hackmann, T. Wright, A. S. | Children (Basel) | 2020 |
emergence agitation |
| Preoperative Nutritional Status and Risk for Subsyndromal Delirium in Older Adults Following Joint Replacement Surgery | Denny, D. L. Trotter, T. Lindseth, G. | Orthopedic nursing | 2020 |
aged |
| Non-pharmacological interventions to reduce the incidence and duration of delirium in critically ill patients: A systematic review and network meta-analysis | Deng, L. X. Cao, L. Zhang, L. N. Peng, X. B. Zhang, L. | J Crit Care | 2020 |
Delirium prevention |
| Multidimensional nursing interventions effect on delirium and hospital admission duration | Dehghani, S. Asadizaker, M. Adineh, M. Maraghi, E. Akbarian, S. Ramezani, B. | International Journal of Pharmaceutical and Phytopharmacological Research | 2020 |
IRCT20181005041233N1 |
| Effects of pain, sedation and delirium monitoring on clinical and economic outcome: A retrospective study | Deffland, M. Spies, C. Weiss, B. Keller, N. Jenny, M. Kruppa, J. Balzer, F. | PLoS ONE | 2020 |
NCT02265263 |
| The association of post-operative delirium with health-related quality of life and mortality after lung transplantation | DeBolt, C. Gao, Y. Sutter, N. Soong, A. Trinh, B. N. Kukreja, J. Kleinhenz, M. Venado, A. Leard, L. E. Hays, S. Greenland, J. R. Shah, R. J. Douglas, V. Kolaitis, N. A. Diamond, J. M. Smith, P. J. Singer, J. P. | American Journal of Respiratory and Critical Care Medicine | 2020 |
adult |
| Development and validation of a delirium risk prediction preoperative model for cardiac surgery patients (DELIPRECAS): An observational multicentre study | de la Varga-Martínez, O. Gómez-Pesquera, E. Muñoz-Moreno, M. F. Marcos-Vidal, J. M. López-Gómez, A. Rodenas-Gómez, F. Ramasco, F. Álvarez-Refojo, F. Tamayo, E. Gómez-Sánchez, E. | J Clin Anesth | 2020 |
Cardiac surgery |