What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- The value of screening for cognition, depression, and frailty in patients referred for TAVI
- Authors
- Khan, M. M. Lanctôt, K. L. Fremes, S. E. Wijeysundera, H. C. Radhakrishnan, S. Gallagher, D. Gandell, D. Brenkel, M. C. Hazan, E. L. Docteur, N. G. Herrmann, N.
- Year
- 2019
- Journal
- Clinical Interventions in Aging
- Abstract
Background: Current surgical risk assessment tools fall short of appreciating geriatric risk factors including cognitive deficits, depressive, and frailty symptoms that may worsen outcomes post-transcatheter aortic valve implantation (TAVI). This study hypothesized that a screening tool, SMARTIE, would improve detection of these risks pre-TAVI, and thus be predictive of postoperative delirium (POD) and 30-day mortality post-TAVI. Design: Prospective observational cohort study, using a historical cohort for comparison. Participants: A total of 234 patients (age: 82.2±6.7 years, 59.4% male) were included. Half were screened using SMARTIE. Methods: The SMARTIE cohort was assessed for cognitive deficits and depressive symptoms using the Mini-Cog test and PHQ-2, respectively. Measures of frailty included activities of daily living inventory, the Timed Up and Go test and grip strength. For the pre-SMARTIE cohort, we extracted cognitive deficits, depression and frailty symptoms from clinic charts. The incidence of POD and 30-day mortality were recorded. Bivariate chi-square analysis or t-tests were used to report associations between SMARTIE and pre-SMARTIE groups. Multivariable logistic regression models were employed to identify independent predictors of POD and 30-day mortality. Results: More patients were identified with cognitive deficits (χ2=11.73, p=0.001), depressive symptoms (χ2=8.15, p=0.004), and physical frailty (χ2=5.73, p=0.017) using SMARTIE. Cognitive deficits were an independent predictor of POD (OR: 8.4, p<0.01) and 30-day mortality (OR: 4.04, p=0.03). Conclusion: This study emphasized the value of screening for geriatric risk factors prior to TAVI by demonstrating that screening increased identification of at-risk patients. It also confirmed findings that cognitive deficits are predictive of POD and mortality following TAVI.
- PMID
- Keywords
activity of daily living assessment
aged
article
cognitive defect
cognitive function test
cohort analysis
controlled study
dementia
depression
female
frailty
grip strength
human
incidence
major clinical study
male
mild cognitive impairment
Mini Cog test
mortality rate
multivariate logistic regression analysis
observational study
Patient Health Questionnaire 2
postoperative delirium
prospective study
screening
screening for and managing risk factors in TAVI an interdisciplinary endeavour
timed up and go test
transcatheter aortic valve implantation
- Page(s)
- 841-8
- Volume
- 14
- Issue
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| Incidence of delirium following hospitalization of elderly people with fractures: risk factors and mortality | Lima, B. R. Nunes, B. K. G. Guimarães, Lcdc Almeida, L. F. Pagotto, V. | Rev Esc Enferm USP | 2021 |
Aged |
| Regional Nerve Block Decreases the Incidence of Postoperative Delirium in Elderly Hip Fracture | Lim, E. J. Koh, W. U. Kim, H. Kim, H. J. Shon, H. C. Kim, J. W. | J Clin Med | 2021 |
delirium |
| Effects of perioperative interventions for preventing postoperative delirium: A protocol for systematic review and meta-analysis of randomized controlled trials | Li, X. Wang, Y. Liu, J. Xiong, Y. Chen, S. Han, J. Xie, W. Wu, Q. | Medicine (Baltimore) | 2021 |
Delirium/*prevention & control |
| Developing a machine learning model to identify delirium risk in geriatric internal medicine inpatients | Li, Q. Zhao, Y. Chen, Y. Yue, J. Xiong, Y. | Eur Geriatr Med | 2021 |
Delirium |
| Development and validation of a risk score for predicting postoperative delirium after major abdominal surgery by incorporating preoperative risk factors and surgical Apgar score | Li, G. H. Zhao, L. Lu, Y. Wang, W. Ma, T. Zhang, Y. X. Zhang, H. | J Clin Anesth | 2021 |
Bootstrapping |
| Non-Pharmacological Nursing Interventions for Prevention and Treatment of Delirium in Hospitalized Adult Patients: Systematic Review of Randomized Controlled Trials | Lee, Y. Lee, J. Kim, J. Jung, Y. | Int J Environ Res Public Health | 2021 |
Adult |
| Association of natural light exposure and delirium according to the presence or absence of windows in the intensive care unit | Lee, H. J. Bae, E. Lee, H. Y. Lee, S. M. Lee, J. | Acute Crit Care | 2021 |
delirium |
| Knowledge, barriers, and training needs of nurses working in delirium care | Lee, G. Roh, Y. S | Nurs Crit Care | 2021 |
barrier |
| Causes and Predictors of 30-Day Readmission in Elderly Patients With Delirium | Lau, H. L. Patel, S. D. Garg, N. | Neurol Clin Pract | 2021 |
Readmission rate, Delirium, Hospitalization, Length of stay, Post discharge care |
| Comparison of Antipsychotics for the Treatment of Patients With Delirium and QTc Interval Prolongation: A Clinical Decision Analysis | Kurisu, K. Yoshiuchi, K. | Front Psychiatry | 2021 |
QTc prolongation |
| The Polish Version of the Nursing Delirium Screening Scale (NuDESC PL)-Experience of Using in Nursing Practice in Cardiac Surgery Intensive Care Unit | Krupa, S. Dorota, O. Friganovic, A. Mędrzycka-Dąbrowska, W. Jurek, K. | Int J Environ Res Public Health | 2021 |
Cardiac Surgical Procedures/adverse effects |
| Associations of delirium with urinary tract infections and asymptomatic bacteriuria in adults aged 65 and older: A systematic review and meta-analysis | Krinitski, D. Kasina, R. Klöppel, S. Lenouvel, E. | J Am Geriatr Soc | 2021 |
asymptomatic bacteriuria |
| Prevalence and Factors Affecting Postoperative Delirium in a Neurosurgical Intensive Care Unit | Kose, G. Şirin, K. Inel, M. B. Mertoglu, S. Aksakal, R. Kurucu, Ş | J Neurosci Nurs | 2021 |
Cross-Sectional Studies |
| Effect of hypertension and medication use regularity on postoperative delirium after maxillofacial tumors radical surgery | Kong, S. Wang, J. Xu, H. Wang, K. | Oncotarget | 2021 |
hypertension |
| Perioperative Electroencephalogram Spectral Dynamics Related to Postoperative Delirium in Older Patients | Koch, S. Windmann, V. Chakravarty, S. Kruppa, J. Yürek, F. Brown, E. N. Winterer, G. Spies, C. | Anesth Analg | 2021 |
Electroencephalography, Postoperative delirium, Surgery, Spectral edge frequency |
| Is dislocation following total hip arthroplasty caused while suffering from delirium? | Kobayashi, T. Morimoto, T. Sonohata, M. Mawatari, M. | Nagoya J Med Sci | 2021 |
dislocation |
| Availability of preoperative neutrophil-lymphocyte ratio to predict postoperative delirium after head and neck free-flap reconstruction: A retrospective study | Kinoshita, H. Saito, J. Takekawa, D. Ohyama, T. Kushikata, T. Hirota, K. | PLoS One | 2021 |
Postoperative delirium, ICU delirium, Neutrophil-lymphocyte ratio, Surgery, Length of Stay |
| Delirium risk of histamine-2 receptor antagonists and proton pump inhibitors: A study based on the adverse drug event reporting database in Japan | Kikkawa, N. Sogawa, R. Monji, A. Sumi, S. Murakawa-Hirachi, T. Kubo, T. Eguchi, Y. Miyamoto, Y. Kamo, M. Tobita, S. Yukawa, M. Uchida, R. Egoshi, M. Shimanoe, C. | Gen Hosp Psychiatry | 2021 |
Delirium |
| Delirium in neurosurgery: a systematic review and meta-analysis | Kappen, P. R. Kakar, E. Dirven, C. M. F. van der Jagt, M. Klimek, M. Osse, R. J. Vincent, Apje | Neurosurg Rev | 2021 |
Delirium |
| Risk factors for postoperative delirium and subsyndromal delirium in older patients in the surgical ward: A prospective observational study | Kanno, M. Doi, M. Kubota, K. Kanoya, Y. | PLoS One | 2021 |
Postoperative delirium, Subsyndromal delirium, Surgery, CAM |
| Diagnostic accuracy and clinical applicability of the Swedish version of the 4AT assessment test for delirium detection, in a mixed patient population and setting | Johansson, Y. A. Tsevis, T. Nasic, S. Gillsjö, C. Johansson, L. Bogdanovic, N. Kenne Sarenmalm, E | BMC Geriatr | 2021 |
Aged |
| In-Hospital Delirium as a Prognostic Factor for New Cognitive Disorder in a 1-Year Post-Hip Fracture Follow-Up | Jaatinen, R. Luukkaala, T. Hongisto, M. T. Helminen, H. Nuotio, M. S. | Dement Geriatr Cogn Disord | 2021 |
Cognition |
| Italian version of the short 10/66 dementia diagnostic schedule: a validation study | Ibnidris, A. Piumatti, G. Carlevaro, F. Fadda, M. Magno, F. Magistro, D. Albanese, E. | BMJ Open | 2021 |
Aged |
| A Machine Learning-Based Algorithm for the Prediction of Intensive Care Unit Delirium (PRIDE): Retrospective Study | Hur, S. Ko, R. E. Yoo, J. Ha, J. Cha, W. C. Chung, C. R. | JMIR Med Inform | 2021 |
clinical prediction |
| The effect of evidence-based cluster nursing intervention on the incidences of delirium and the prognoses of ICU patients | Huang, S. Xu, J. Du, Y. Wang, Y. Wei, H. Wei, G. Hu, M. | Am J Transl Res | 2021 |
Evidence-based medicine |
| Impact of dexmedetomidine supplemented analgesia on delirium in patients recovering from orthopedic surgery: A randomized controlled tria | Hong, H. Zhang, D. Z. Li, M. Wang, G. Zhu, S. N. Zhang, Y. Wang, D. X. Sessler, D. I. | BMC Anesthesiol | 2021 |
Delirium |
| Effects of a simulation-based education programme on delirium care for critical care nurses: A randomized controlled trial | Ho, M. H. Yu, L. F. Lin, P. H. Chang, H. R. Traynor, V. Huang, W. C. Montayre, J. Chen, K. H. | J Adv Nurs | 2021 |
Clinical Competence |
| Postoperative Delirium in Older Patients: A Systematic Review of Assessment and Incidence of Postoperative Delirium | Ho, M. H. Nealon, J. Igwe, E. Traynor, V. Chang, H. R. Chen, K. H. Montayre, J. | Worldviews Evid Based Nurs | 2021 |
Aged |
| Harmonization of Four Delirium Instruments: Creating Crosswalks and the Delirium Item-Bank (DEL-IB) | Helfand, B. K. I. Detroyer, E. Milisen, K. Adamis, D. Metzger, E. D. Boudreaux, E. D. Inouye, S. K. Jones, R. N. | Am J Geriatr Psychiatry | 2021 | |
| Association between genetic variants of the cholinergic system and postoperative delirium and cognitive dysfunction in elderly patients | Heinrich, M. Sieg, M. Kruppa, J. Nürnberg, P. Schreier, P. H. Heilmann-Heimbach, S. Hoffmann, P. Nöthen, M. M. Janke, J. Pischon, T. Slooter, A. J. C. Winterer, G. Spies, C. D. | BMC Med Genomics | 2021 |
Chrm2 |
| Risk of delirium and impaired neurological outcome associated with delay in neurorehabilitation after acquired brain injury | Hansen, P. M. Lauridsen, J. T. Frandsen, N. S. | Dan Med J | 2021 |
*Brain Injuries |
| Prevalence, Risk Factors, and Impact of Delirium on Hospitalized Older Adults With Dementia: A Systematic Review and Meta-Analysis | Han, Q. Y. C. Rodrigues, N. G. Klainin-Yobas, P. Haugan, G. Wu, X. | J Am Med Dir Assoc | 2021 |
Dementia |
| Urinary albumin creatinine ratio associated with postoperative delirium in elderly patients undergoing elective non-cardiac surgery: A prospective observational study | Guan, H. L. Liu, H. Hu, X. Y. Abdul, M. Dai, M. S. Gao, X. Chen, X. F. Zhou, Y. Sun, X. Zhou, J. Li, X. Zhao, Q. Zhang, Q. Q. Wang, J. Han, Y. Cao, J. L. | CNS Neurosci Ther | 2021 |
delirium |
| Cognitive Impairment and Delirium in Older Patients Undergoing Major Head and Neck Surgery | Goldstein, D. P. Blasco, M. de Almeida, J. Su, J. Xu, W. Cohen, M. Sklar, M. Alibhai, S | Otolaryngol Head Neck Surg | 2021 |
clock draw test |
| What prompts patients to present with delirium? | Gibb, K. Krywonos, A. Shah, R. Jha, A. Davis, D. | Eur Geriatr Med | 2021 |
Adult |
| Admission Systolic Blood Pressure Predicts Post-Operative Delirium of Acute Aortic Dissection Patients in the Intensive Care Unit | Fu, Z. Xu, Q. Zhang, C. Bai, H. Chen, X. Zhang, Y. Luo, W. Lin, G. | Int J Gen Med | 2021 |
acute Stanford type A aortic dissection |
| Postoperative Delirium in Patients After Brain Tumor Surgery | French, J. Weber, T. Ge, B. Litofsky, N. S. | World Neurosurg | 2021 |
Confusion assessment method |
| Physical Restraints and Post-Traumatic Stress Disorder in Survivors of Critical Illness. A Systematic Review and Meta-analysis | Franks, Z. M. Alcock, J. A. Lam, T. Haines, K. J. Arora, N. Ramanan, M. | Ann Am Thorac Soc | 2021 |
Adult |
| Long-Term Outcomes in ICU Patients with Delirium: A Population-based Cohort Study | Fiest, K. M. Soo, A. Hee Lee, C. Niven, D. J. Ely, E. W. Doig, C. J. Stelfox, H. T. | Am J Respir Crit Care Med | 2021 |
Adolescent |
| The effect of foot reflexology massage on delirium and sleep quality following cardiac surgery: A randomized clinical trial | Fazlollah, A. Babatabar Darzi, H. Heidaranlu, E. Moradian, S. T. | Complement Ther Med | 2021 |
*Cardiac Surgical Procedures/adverse effects |
| A delirium prevalence audit and a pre and post evaluation of an interprofessional education intervention to increase staff knowledge about delirium in older adults | Ewens, B. Seaman, K. Whitehead, L. Towell-Barnard, A. Young, M. | BMC Nurs | 2021 |
Delirium |
| Anaesthetic depth and delirium after major surgery: a randomised clinical trial | Evered, L. A. Chan, M. T. V. Han, R. Chu, M. H. M. Cheng, B. P. Scott, D. A. Pryor, K. O. Sessler, D. I. Veselis, R. Frampton, C. Sumner, M. Ayeni, A. Myles, P. S. Campbell, D. Leslie, K. Short, T. G. | Br J Anaesth | 2021 |
anaesthesia |
| Association of preoperative frailty with postoperative delirium in elderly orthopedic trauma patients | Esmaeeli, S. Franco-Garcia, E. Akeju, O. Heng, M. Zhou, C. Azocar, R. J. Quraishi, S. A. | Aging Clin Exp Res | 2021 |
Cognition |
| Prevention of postoperative delirium after cardiovascular surgery: A team-based approach | Enomoto, K. Kosaka, S. Kimura, T. Matsubara, M. Kitada, Y. Mieno, M. Okamura, H. | J Thorac Cardiovasc Surg | 2021 |
Delirium Team Approach program |
| Serum Levels of S100β, Neuron-Specific Enolase, Glial Fibrillary Acidic Protein in Kidney Transplant Recipients and Donors: A Prospective Cohort Study | Dinc, B. Yılmaz, V. T. Aslan, M. Aycan, I. O. Kiraz, N. Kisaoglu, A. Dandin, O. Hadimioglu, N. Ertug, Z. | Transplant Proc | 2021 |
Nephrectomy, Kidney transplant, Neuromarkers, Postoperative delirium |
| Delirium and Its Pharmacological Causes in Older People, Part 1 | DeMaagd, G. A. DeMaagd, D. R. Philip, A. Coalter, C. F. | Sr Care Pharm | 2021 |
Aged |
| Potentially inappropriate prescribing in dementia, multi-morbidity and incidence of adverse health outcomes | Delgado, J. Jones, L. Bradley, M. C. Allan, L. M. Ballard, C. Clare, L. Fortinsky, R. H. Hughes, C. M. Melzer, D. | Age Ageing | 2021 |
Aged |
| The Nexus Between Sleep Disturbance and Delirium Among Intensive Care Patients | Delaney, L. J. Litton, E. Van Haren, F. | Crit Care Nurs Clin North Am | 2021 |
Critical Care |
| Opportunities for quality improvement in the morbidity pattern of older adults undergoing pulmonary lobectomy for cancer | De León, L. E. Rochefort, M. M. Bravo-Iñiguez, C. E. Fox, S. W. Tarascio, J. N. Cardin, K. DuMontier, C. Frain, L. N. Jaklitsch, M. T. | J Geriatr Oncol | 2021 |
Aged |
| Palliative sedation in patients with advanced cancer in a specialized unit in a middle-income country: A retrospective cohort study | de Araujo, C. Z. S. de Araújo, L. Z. S. Nassar Junior, A. P. | Palliat Support Care | 2021 |
Cancer |
| Development and Implementation of a Multicomponent Protocol to Promote Sleep and Reduce Delirium in a Medical Intensive Care Unit | Darby, A. Northam, K. Austin, C. A. Chang, L. Campbell-Bright, S | Ann Pharmacother | 2021 |
critical care |
| Effect of Interventions With a Clinical Decision Support System for Hospitalized Older Patients: Systematic Review Mapping Implementation and Design Factors | Damoiseaux-Volman, B. A. van der Velde, N. Ruige, S. G. Romijn, J. A. Abu-Hanna, A. Medlock, S. | JMIR Med Inform | 2021 |
aged |
| Sevoflurane-Remifentanil Versus Propofol-Remifentanil Anesthesia During Noncardiac Surgery for Patients with Coronary Artery Disease - A Prospective Study Between 2016 and 2017 at a Single Center | Dai, Z. Lin, M. Li, Y. Gao, W. Wang, P. Lin, J. Wan, Z. Jiang, Y. | Med Sci Monit | 2021 |
Acute Coronary Syndrome, Coronary Artery Disease, Propofol |
| Symptom trajectories for palliative care inpatients with and without hyperactive delirium in the last week of life | Dai, Y. Walpole, G. Ding, J. Scanlon, C. Ho, L. Khoo, R. H. Huang, C. Cook, A. William, L. Johnson, C. E. | J Adv Nurs | 2021 |
end of life |
| Subtypes of delirium after ischaemic stroke-predisposing factors and outcomes: a prospective observational study (PROPOLIS) | Czyzycki, M. Klimiec-Moskal, E. Chrobak, A. A. Pera, J. Slowik, A. Dziedzic, T. | Eur J Neurol | 2021 |
delirium |
| Effectiveness of a Delirium Prevention Initiative on an Inpatient Neuroscience Unit | Cyrus, T. Wenthold, R. Hall, B. Tu, L. Hedquist, K. Omodt, J. Kozub, E. Guthrie, P. F. | J Neurosci Nurs | 2021 |
Clinical Competence |
| Association Between Cerebral Desaturation and Postoperative Delirium in Thoracotomy With One-Lung Ventilation: A Prospective Cohort Study | Cui, F. Zhao, W. Mu, D. L. Zhao, X. Li, X. Y. Wang, D. X. Jia, H. Q. Dai, F. Meng, L. | Anesth Analg | 2021 |
Aged |
| Factors for Timely Identification of Possible Occurrence of Delirium in Palliative Care: A Prospective Observational Study | Corli, O. Santucci, C. Uggeri, S. Bosetti, C. Cattaneo, M. Ermolli, D. Varrassi, G. Myrcik, D. Paladini, A. Rekatsina, M. Gerosa, C. Ornaghi, M. Roccasalva, A. Santambrogio, P. Beretta, M. | Adv Ther | 2021 |
*Delirium/chemically induced/diagnosis/epidemiology |
| A Processed Electroencephalogram-Based Brain Anesthetic Resistance Index Is Associated With Postoperative Delirium in Older Adults: A Dual Center Study | Cooter Wright, M. Bunning, T. Eleswarpu, S. S. Heflin, M. T. McDonald, S. R. Lagoo-Deenadalayan, S. Whitson, H. E. Martinez-Camblor, P. Deiner, S. G. Berger, M. | Anesth Analg | 2021 |
age factors, anesthesia, methods, delirium, surgery/prevention & control, Electroencephalography, drug effects |
| Implementation and Routinization of the ABCDE Bundle: A Mixed Methods Evaluation | Collinsworth, A. W. Brown, R. Cole, L. Jungeblut, C. Kouznetsova, M. Qiu, T. Richter, K. M. Smith, S. Masica, A. L. | Dimens Crit Care Nurs | 2021 |
Adult |
| Prediction of delirium using data mining: A systematic review | Chua, S. J. Wrigley, S. Hair, C. Sahathevan, R | J Clin Neurosci | 2021 |
Area Under Curve |
| Determinants of Non-emergency Use of Control Interventions in Older Canadian Psychiatric Inpatients: Analysizing the InterRAI Mental Health Electronic Health Records | Cheung, G. Mah, T. M. Barak, Y. Hirdes, J. P. | Front Psychiatry | 2021 |
aggression |
| Assessment of preoperative frailty and identification of patients at risk for postoperative delirium in cardiac intensive care units: a prospective observational study | Cheng, H. W. Liu, C. Y. Chen, Y. S. Shih, C. C. Chen, W. Y. Chiou, A. F. | Eur J Cardiovasc Nurs | 2021 |
Anxiety |
| Preoperative prognostic nutritional index is useful factor for predicting postoperative delirium after primary total joint arthroplasty | Chen, J. Zheng, C. Zhong, J. Zhao, G. Shi, J. Huang, G. Wei, Y. Wang, S. Yu, J. Xia, J. | BMC Musculoskelet Disord | 2021 |
Aged |
| Case-control study on the interplay between immunoparalysis and delirium after cardiac surgery | CheheiliSobbi, S. Peters van Ton, A. M. Wesselink, E. M. Looije, M. F. Gerretsen, J. Morshuis, W. J. Slooter, A. J. C. Abdo, W. F. Pickkers, P. van den Boogaard, M. | J Cardiothorac Surg | 2021 |
*Cardiac Surgical Procedures/adverse effects |
| Diagnostic accuracy of the "4 A's Test" delirium screening tool for the postoperative cardiac surgery ward | Chang, Y. Ragheb, S. M. Oravec, N. Kent, D. Nugent, K. Cornick, A. Hiebert, B. Rudolph, J. L. MacLullich, A. M. J. Arora, R. C. | J Thorac Cardiovasc Surg | 2021 |
4at |
| Meta-analysis of ICU Delirium Biomarkers and Their Alignment With the NIA-AA Research Framework | Chan, C. K. Song, Y. Greene, R. Lindroth, H. Khan, S. Rios, G. Khan, B. Wang, S | Am J Crit Care | 2021 |
Alzheimer Disease |
| Sedation strategy and ICU delirium: a multicentre, population-based propensity score-matched cohort study | Casault, C. Soo, A. Lee, C. H. Couillard, P. Niven, D. Stelfox, T. Fiest, K. | BMJ Open | 2021 |
Adult |
| Health outcomes after the implementation of multidisciplinary clinical guidelines for the care of hip fractures | Casanova Querol, T. Santiago Bautista, J. M. Lafuente Salinas, M. Güell Farré, E. Girós Torres, J. Martín-Baranera, M. Miralles Basseda, R. | Rev Clin Esp (Barc) | 2021 |
Atención continuada |
| Pharmacological and non-pharmacological interventions to prevent delirium in critically ill patients: a systematic review and network meta-analysis | Burry, L. D. Cheng, W. Williamson, D. R. Adhikari, N. K. Egerod, I. Kanji, S. Martin, C. M. Hutton, B. Rose, L. | Intensive Care Med | 2021 |
Adult |
| Dexmedetomidine for Facilitating Mechanical Ventilation Extubation in Difficult-to-Wean ICU Patients: Systematic Review and Meta-Analysis of Clinical Trials | Buckley, M. S. Smithburger, P. L. Wong, A. Fraser, G. L. Reade, M. C. Klein-Fedyshin, M. Ardiles, T. Kane-Gill, S. L. | J Intensive Care Med | 2021 |
Adult |
| Risk factors for postoperative delirium: An umbrella review of systematic reviews | Bramley, P. McArthur, K. Blayney, A. McCullagh, I. | Int J Surg | 2021 |
*Cognitive Dysfunction |
| Inadequate emergence after anesthesia for elective cancer surgery: a single-center cohort study | Braga, A. Abelha, F. | Braz J Anesthesiol | 2021 |
Cancer surgeries |
| Asthma and delirium episodes during hospitalization | Bozek, A. Fiolka, R. Zajac, M. | Aging Med (Milton) | 2021 |
asthma |
| A pragmatic assessment of proton pump inhibitors vs. histamine type 2 receptor antagonists on clinically important gastrointestinal bleeding and mortality when used for stress ulcer prophylaxis in the ICU | Boyd, C. Hassig, T. MacLaren, R. | Pharmacotherapy | 2021 |
critical illness |
| Brain Network Dysfunction in Poststroke Delirium and Spatial Neglect: An fMRI Study | Boukrina, O. Kowalczyk, M. Koush, Y. Kong, Y. Barrett, A. M. | Stroke | 2021 |
MRI, functional |
| Preventing Delirium and Promoting Long-Term Brain Health: A Clinical Trial Design for the Perioperative Cognitive Enhancement (PROTECT) Trial | Atkins, K. J. Scott, D. A. Silbert, B. Pike, K. E. Evered, L. | J Alzheimers Dis | 2021 |
Anesthesia and analgesia |
| Prevalence of Severe Neurocognitive Impairment and Its Association with Socio-Demographics and Functionality Among Ugandan Older Persons: A Hospital-Based Study | Atim, L. M. Kaggwa, M. M. Mamun, M. A. Ashaba, S. Maling, S. | Clin Interv Aging | 2021 |
Aged |
| Clinical Aspects of Palliative Sedation in Prospective Studies. A Systematic Review | Arantzamendi, M. Belar, A. Payne, S. Rijpstra, M. Preston, N. Menten, J. Van der Elst, M. Radbruch, L. Hasselaar, J. Centeno, C. | J Pain Symptom Manage | 2021 |
*Hospice and Palliative Care Nursing |
| Psychometric Properties of Nursing Delirium Screening Scale in Patients Admitted to Intensive Care Units | Amirajam, Z. Asadi-Noran, E. Molaei, B. Adiban, V. Heidarzadeh, M. Hassanpour-Darghah, M. | Indian J Crit Care Med | 2021 |
Delirium |
| Delirium researchers' perspectives of the challenges in delirium biomarker research: A qualitative study | Amgarth-Duff, I. Hosie, A. Caplan, G. A. Agar, M. | PLoS One | 2021 |
Biomarkers/blood |
| Addition of Valerian and Lemon Balm Extract to Quetiapine Reduces Agitation in Critically Ill Patients with Delirium: A Pilot Randomized Clinical Trial | Alikiaie, B. Shahmoradi, E. Yekdaneh, A. Mousavi, S. | Indian J Crit Care Med | 2021 |
Delirium |
| Spinal block and delirium in oncologic patients after laparoscopic surgery in the Trendelenburg position: A randomized controlled trial | Mitsunaga, J. K. Junior Calsavara, V. F. Onari, E. S. Arantes, V. M. Akamine, C. P. Handa, A. M. Quezada, M. M. C. Ito, F. Y. Porto, A. C. S. Giroud Joaquim, E. H. Nakamura, G. | PLoS One | 2021 | |
| Perioperative Vascular Biomarker Profiling in Elective Surgery Patients Developing Postoperative Delirium: A Prospective Cohort Study | Menzenbach, J. Frede, S. Petras, J. Guttenthaler, V. Kirfel, A. Neumann, C. Mayr, A. Wittmann, M. Coburn, M. Klaschik, S. Hilbert, T. | Biomedicines | 2021 |
Ccl2 |
| Preliminary Study of Serum Biomarkers Associated With Delirium After Major Cardiac Surgery | McKay, T. B. Rhee, J. Colon, K. Adelsberger, K. Turco, I. Mueller, A. Qu, J. Akeju, O. | J Cardiothorac Vasc Anesth | 2021 |
Fgf |
| Stratified delirium risk using prescription medication data in a state-wide cohort | McCoy, T. H., Jr. Castro, V. M. Hart, K. L. Perlis, R. H. | Gen Hosp Psychiatry | 2021 |
Cohort study |
| Nutritional Risk at intensive care unit admission and outcomes in survivors of critical illness | Mart, M. F. Girard, T. D. Thompson, J. L. Whitten-Vile, H. Raman, R. Pandharipande, P. P. Heyland, D. K. Ely, E. W. Brummel, N. E. | Clin Nutr | 2021 |
Activities of daily living |
| Risk Factors for Delirium Are Different in the Very Old: A Comparative One-Year Prospective Cohort Study of 5,831 Patients | Marquetand, J. Bode, L. Fuchs, S. Hildenbrand, F. Ernst, J. von Kaenel, R. Boettger, S. | Front Psychiatry | 2021 |
comparison |
| Plasma interleukin-6 is a potential predictive biomarker for postoperative delirium among acute type a aortic dissection patients treated with open surgical repair | Lv, X. C. Lin, Y. Wu, Q. S. Wang, L. Hou, Y. T. Dong, Y. Chen, L. W. | J Cardiothorac Surg | 2021 |
Adult |
| Association of early and later depressive symptoms with functional outcome after ischemic stroke | Lopatkiewicz, A. M. Pera, J. Slowik, A. Dziedzic, T. | J Neural Transm (Vienna) | 2021 |
Cognitive decline |
| Development and validation of a postoperative delirium prediction model for pediatric patients: A prospective, observational, single-center study | Lin, N. Liu, K. Feng, J. Chen, R. Ying, Y. Lv, D. Zhou, Y. Xu, H. | Medicine (Baltimore) | 2021 |
Adolescent |
| Patients' experiences of delirium: A systematic review and meta-summary of qualitative research | Kuusisto-Gussmann, E. Höckelmann, C. von der Lühe, V. Schmädig, R. Baltes, M. Stephan, A. | J Adv Nurs | 2021 |
delirium |
| Effects of case-based confusion assessment methods for intensive care unit training on delirium knowledge and delirium assessment accuracy of intensive care units: A quasi-experimental study | Kim, Y. N. Kim, D. H. | Nurse Educ Today | 2021 |
Critical Illness |
| Bridging the Gap Between the Intensive Care Unit and the Acute Medical Care Unit | Kim, E. Kast, C. Afroz-Hossain, A. Qiu, M. Pappas, K. Sinvani, L. | Am J Crit Care | 2021 | |
| Preoperative MRI brain phenotypes are related to postoperative delirium in older individuals | Kant, I. M. J. Slooter, A. J. C. Jaarsma-Coes, M. van Montfort, S. J. T. Witkamp, T. D. Pasma, W. Hendrikse, J. de Bresser, J. | Neurobiol Aging | 2021 |
Brain phenotypes |
| Pre-Existing Psychiatric Illness Is Associated With an Increased Risk of Delirium in Patients With Acute Respiratory Distress Syndrome | Kalra, S. S. Jaber, J. Alzghoul, B. N. Hyde, R. Parikh, S. Urbine, D. Reddy, R. | J Intensive Care Med | 2021 |
Ards |
| Development and internal validation of a predictive model of cognitive decline 36 months following elective surgery | Jones, R. N. Tommet, D. Steingrimsson, J. Racine, A. M. Fong, T. G. Gou, Y. Hshieh, T. T. Metzger, E. D. Schmitt, E. M. Tabloski, P. A. Travison, T. G. Vasunilashorn, S. M. Abdeen, A. Earp, B. Kunze, L. Lange, J. Vlassakov, K. Dickerson, B. C. Marcantonio | Alzheimers Dement (Amst) | 2021 |
cognitive decline |
| The performance of the Dutch Safety Management System frailty tool to predict the risk of readmission or mortality in older hospitalised cardiac patients | Jepma, P. Verweij, L. Tijssen, A. Heymans, M. W. Flierman, I. Latour, C. H. M. Peters, R. J. G. Scholte Op Reimer, W. J. M. Buurman, B. M. Ter Riet, G. | BMC Geriatr | 2021 |
Aged |
| Outcomes of transcatheter aortic valve replacement in patients with cognitive dysfunction | Jain, V. Kalra, A. Panhwar, M. S. Bansal, A. Nowacki, A. Bhatia, K. Gupta, T. Ineman, N. L. Khan, S. U. Krishnaswamy, A. Reed, G. W. Puri, R. Kapadia, S. R. Svensson, L. G. Kanaa, N. A. Lahorra, J. A. | J Am Geriatr Soc | 2021 |
cognitive impairment |
| The Importance of Delirium and Delirium Prevention in Older Adults During Lockdowns | Inouye, S. K. | JAMA | 2021 |
Aged |