What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Exercise for acutely hospitalised older medical patients
- Authors
- Hartley, P. Keating, J. L. Jeffs, K. J. Raymond, M. J. Smith, T. O
- Year
- 2022
- Journal
- Cochrane Database Syst Rev
- Abstract
BACKGROUND: Approximately 30% of hospitalised older adults experience hospital-associated functional decline. Exercise interventions that promote in-hospital activity may prevent deconditioning and thereby maintain physical function during hospitalisation. This is an update of a Cochrane Review first published in 2007. OBJECTIVES: To evaluate the benefits and harms of exercise interventions for acutely hospitalised older medical inpatients on functional ability, quality of life (QoL), participant global assessment of success and adverse events compared to usual care or a sham-control intervention. SEARCH METHODS: We used standard, extensive Cochrane search methods. The latest search date was May 2021. SELECTION CRITERIA: We included randomised or quasi-randomised controlled trials evaluating an in-hospital exercise intervention in people aged 65 years or older admitted to hospital with a general medical condition. We excluded people admitted for elective reasons or surgery. DATA COLLECTION AND ANALYSIS: We used standard Cochrane methods. Our major outcomes were 1. independence with activities of daily living; 2. functional mobility; 3. new incidence of delirium during hospitalisation; 4. QoL; 5. number of falls during hospitalisation; 6. medical deterioration during hospitalisation and 7. participant global assessment of success. Our minor outcomes were 8. death during hospitalisation; 9. musculoskeletal injuries during hospitalisation; 10. hospital length of stay; 11. new institutionalisation at hospital discharge; 12. hospital readmission and 13. walking performance. We used GRADE to assess certainty of evidence for each major outcome. We categorised exercise interventions as: rehabilitation-related activities (interventions designed to increase physical activity or functional recovery, but did not follow a specified exercise protocol); structured exercise (interventions that included an exercise intervention protocol but did not include progressive resistance training); and progressive resistance exercise (interventions that included an element of progressive resistance training). MAIN RESULTS: We included 24 studies (nine rehabilitation-related activity interventions, six structured exercise interventions and nine progressive resistance exercise interventions) with 7511 participants. All studies compared exercise interventions to usual care; two studies, in addition to usual care, used sham interventions. Mean ages ranged from 73 to 88 years, and 58% of participants were women. Several studies were at high risk of bias. The most common domain assessed at high risk of bias was measurement of the outcome, and five studies (21%) were at high risk of bias arising from the randomisation process. Exercise may have no clinically important effect on independence in activities of daily living at discharge from hospital compared to controls (16 studies, 5174 participants; low-certainty evidence). Five studies used the Barthel Index (scale: 0 to 100, higher scores representing greater independence). Mean scores at discharge in the control groups ranged from 42 to 96 points, and independence in activities of daily living was 1.8 points better (0.43 worse to 4.12 better) with exercise compared to controls. The minimally clinical important difference (MCID) is estimated to be 11 points. We are uncertain regarding the effect of exercise on functional mobility at discharge from the hospital compared to controls (8 studies, 2369 participants; very low-certainty evidence). Three studies used the Short Physical Performance Battery (SPPB) (scale: 0 to 12, higher scores representing better function) to measure functional mobility. Mean scores at discharge in the control groups ranged from 3.7 to 4.9 points on the SPPB, and the estimated effect of the exercise interventions was 0.78 points better (0.02 worse to 1.57 better). A change of 1 point on the SPPB represents an MCID. We are uncertain regarding the effect of exercise on the incidence of delirium during hospitalisation compared to controls (7 trials, 2088 participants; very low-certainty evidence). The incidence of delirium during hospitalisation was 88/1091 (81 per 1000) in the control group compared with 70/997 (73 per 1000; range 47 to 114) in the exercise group (RR 0.90, 95% CI 0.58 to 1.41). Exercise interventions may result in a small clinically unimportant improvement in QoL at discharge from the hospital compared to controls (4 studies, 875 participants; low-certainty evidence). Mean QoL on the EuroQol 5 Dimensions (EQ-5D) visual analogue scale (VAS) (scale: 0 to 100, higher scores representing better QoL) ranged between 48.9 and 64.7 in the control group at discharge from the hospital, and QoL was 6.04 points better (0.9 better to 11.18 better) with exercise. A change of 10 points on the EQ-5D VAS represents an MCID. No studies measured participant global assessment of success. Exercise interventions did not affect the risk of falls during hospitalisation (moderate-certainty evidence). The incidence of falls was 31/899 (34 per 1000) in the control group compared with 31/888 (34 per 1000; range 20 to 57) in the exercise group (RR 0.99, 95% CI 0.59 to 1.65). We are uncertain regarding the effect of exercise on the incidence of medical deterioration during hospitalisation (very low-certainty evidence). The incidence of medical deterioration in the control group was 101/1417 (71 per 1000) compared with 96/1313 (73 per 1000; range 44 to 120) in the exercise group (RR 1.02, 95% CI 0.62 to 1.68). Subgroup analyses by different intervention categories and by the use of a sham intervention were not meaningfully different from the main analyses. AUTHORS’ CONCLUSIONS: Exercise may make little difference to independence in activities of daily living or QoL, but probably does not result in more falls in older medical inpatients. We are uncertain about the effect of exercise on functional mobility, incidence of delirium and medical deterioration. Certainty of evidence was limited by risk of bias and inconsistency. Future primary research on the effect of exercise on acute hospitalisation could focus on more consistent and uniform reporting of participant’s characteristics including their baseline level of functional ability, as well as exercise dose, intensity and adherence that may provide an insight into the reasons for the observed inconsistencies in findings.
- PMID
- Keywords
Aged
Aged, 80 and over
Female
Humans
Male
Activities of Daily Living
*Delirium/epidemiology
Exercise
*Quality of Life
- Page(s)
- Volume
- Issue
Title | Authors | Journal | Year | Keywords |
---|---|---|---|---|
Association between delirium in the intensive care unit and subsequent neuropsychiatric disorders | Brown, K. N. Soo, A. Faris, P. Patten, S. B. Fiest, K. M. Stelfox, H. T. | Crit Care | 2020 |
Aged |
Association of Positive Delirium Screening with Incident Dementia in Skilled Nursing Facilities | Briesacher, B. A. Koethe, B. Olivieri-Mui, B. Saczynski, J. S. Fick, D. M. Devlin, J. W. Marcantonio, E. R. | J Am Geriatr Soc | 2020 |
delirium |
Economic Burden of Postoperative Neurocognitive Disorders Among US Medicare Patients | Boone, M. D. Sites, B. von Recklinghausen, F. M. Mueller, A. Taenzer, A. H. Shaefi, S. | JAMA Netw Open | 2020 |
Aged |
Hospital Elder Life Program in Long-Term Care (HELP-LTC): A Cluster Randomized Controlled Trial | Boockvar, K. S. Judon, K. M. Eimicke, J. P. Teresi, J. A. Inouye, S. K. | J Am Geriatr Soc | 2020 |
delirium |
Pain Incidence, Treatment, and Associated Symptoms in Hospitalized Persons with Dementia | Boltz, M. Resnick, B. Kuzmik, A. Mogle, J. Jones, J. R. Arendacs, R. BeLue, R. Cacchione, P. Galvin, J. E. | Pain Manag Nurs | 2020 | |
Disparities in Physical and Psychological Symptoms in Hospitalized African American and White Persons with Dementia | Boltz, M. BeLue, R. Resnick, B. Kuzmik, A. Galik, E. Jones, J. R. Arendacs, R. Sinvani, L. Mogle, J. Galvin, J. E. | J Aging Health | 2020 |
African Americans |
The prevalence rates and adversities of delirium: Too common and disadvantageous | Boettger, S. Zipser, C. M. Bode, L. Spiller, T. Deuel, J. Osterhoff, G. Ernst, J. Petry, H. Volbracht, J. von Känel, R. | Palliat Support Care | 2020 |
Delirium |
Assessing delirium with nursing care instruments: Evaluation of the cognitive and associated domains | Bode, L. Fuchs, S. Gehrke, S. Ernst, J. Schubert, M. Nuñez, D. G. von Känel, R. Boettger, S. | Palliat Support Care | 2020 |
Assessment |
Iranian Nurses Perception and Practices for Delirium Assessment in Intensive Care Units | Biyabanaki, F. Arab, M. Dehghan, M. | Indian J Crit Care Med | 2020 |
Assessment |
How to fight against overtreatment? Example of neuroleptic prescriptions for acute delirium | Bianchi, C. Blondet, F. Aebischer, O. Méan, M. | Revue Medicale Suisse | 2020 |
neuroleptic agent |
Clinical Presentation of COVID19 in Dementia Patients | Bianchetti, A. Rozzini, R. Guerini, F. Boffelli, S. Ranieri, P. Minelli, G. Bianchetti, L. Trabucchi, M. | Journal of Nutrition, Health and Aging | 2020 |
aged |
Validation of two nurse-based screening tools for delirium in elderly patients in general medical wards | Bergjan, M. Zilezinski, M. Schwalbach, T. Franke, C. Erdur, H. Audebert, H. J. Hauß, A. | BMC Nurs | 2020 |
Confusion |
Prevalence and management of delirium in intensive care units in the Netherlands: An observational multicentre study | Berger, E. Wils, E. J. Vos, P. van Santen, S. Koets, J. Slooter, A. J. C. van der Woude, M. Koopmans, M. Rinket, M. A. Hoiting, O. Hoogendoorn, E. E. Streefkerk, J. O. de Vreede, E. W. Riekerk, B. Simons, K. S. Toscano, E. Schoonderbeek, F. J. Hofstra, L. | Intensive Crit Care Nurs | 2020 |
Critically ill |
Effect of Exogenous Melatonin Administration in Critically Ill Patients on Delirium and Sleep: A Randomized Controlled Trial | Bellapart, J. Appadurai, V. Lassig-Smith, M. Stuart, J. Zappala, C. Boots, R. | Crit Care Res Pract | 2020 | |
Delirium, functional decline and quality of life after transcatheter aortic valve implantation: An explorative study | Beishuizen, S. J. Festen, S. Loonstra, Y. E. van der Werf, H. W. de Rooij, S. E. van Munster, B. C. | Geriatr Gerontol Int | 2020 |
activities of daily living |
Clinical outcomes in patients admitted to hospital with cervical spine fractures or with hip fractures | Baxter, J. Lisk, R. Osmani, A. Yeong, K. Robin, J. Fluck, D. Fry, C. H. Han, T. S. | Intern Emerg Med | 2020 |
Discharge destination |
Frequency and Implications of Complications in the ICU After Status Epilepticus: No Calm After the Storm | Baumann, S. M. Semmlack, S. De Marchis, G. M. Hunziker, S. Rüegg, S. Marsch, S. Sutter, R. | Critical care medicine | 2020 |
adult |
Neurological Complications and Noninvasive Multimodal Neuromonitoring in Critically Ill Mechanically Ventilated COVID-19 Patients | Battaglini, D. Santori, G. Chandraptham, K. Iannuzzi, F. Bastianello, M. Tarantino, F. Ball, L. Giacobbe, D. R. Vena, A. Bassetti, M. Inglese, M. Uccelli, A. Rocco, P. R. M. Patroniti, N. Brunetti, I. Pelosi, P. Robba, C. | Front Neurol | 2020 |
Covid-19 |
Association between plasma tau and postoperative delirium incidence and severity: a prospective observational study | Ballweg, T. White, M. Parker, M. Casey, C. Bo, A. Farahbakhsh, Z. Kayser, A. Blair, A. Lindroth, H. Pearce, R. A. Blennow, K. Zetterberg, H. Lennertz, R. Sanders, R. D. | Br J Anaesth | 2020 |
biomarker |
Neurocovid: Pharmacological Recommendations for Delirium Associated With COVID-19 | Baller, E. B. Hogan, C. S. Fusunyan, M. A. Ivkovic, A. Luccarelli, J. W. Madva, E. Nisavic, M. Praschan, N. Quijije, N. V. Beach, S. R. Smith, F. A. | Psychosomatics | 2020 |
Adrenergic alpha-2 Receptor Agonists/ therapeutic use |
An Implementation Assessment of the Virtual Acute Care for Elders Program From the Perspective of Key Stakeholders | Balentine, C. J. Morris, M. Knight, S. J. Turan, J. M. Flood, K. L. Gutierrez-Meza, D. Macdonald, C. L. Bhatia, S. Brown, C. J. | Ann Surg | 2020 | |
The 'third wave': impending cognitive and functional decline in COVID-19 survivors | Baker, H. A. Safavynia, S. A. Evered, L. A. | Br J Anaesth | 2020 |
Covid-19 |
Presence of urinary symptoms in bacteremic urinary tract infection: a retrospective cohort study of Escherichia coli bacteremia | Bai, A. D. Bonares, M. J. Thrall, S. Bell, C. M. Morris, A. M. | BMC Infect Dis | 2020 |
Aged |
Risk Factors of Postoperative Delirium in Older Adult Spine Surgery Patients: A Meta-Analysis | Baek, W. Kim, Y. M. Lee, H. | AORN J | 2020 |
delirium |
Psychosocial volunteer support for older adults with cognitive impairment: development of MyCare Ageing using a codesign approach via action research | Ayton, D. O'Donnell, R. Vicary, D. Bateman, C. Moran, C. Srikanth, V. K. Lustig, J. Banaszak-Holl, J. Hunter, P. Pritchard, E. Morris, H. Savaglio, M. Parikh, S. Skouteris, H. | BMJ Open | 2020 |
dementia |
The Volunteer Dementia and Delirium Care (VDDC)©: A pre-implementation study exploring perceived acceptability to implementing the program in an acute and subacute metropolitan hospital | Ayton, D. Moran, C. Berkovic, D. Bateman, C. Anderson, K. Blair, A. Soh, S. E. Morello, R. Lim, Y. Y. Liew, D. | Australas J Ageing | 2020 |
delirium |
A call to action for delirium research: Meta-analysis and regression of delirium associated mortality | Aung Thein, M. Z. Pereira, J. V. Nitchingham, A. Caplan, G. A. | BMC Geriatr | 2020 |
Aged |
Accuracy and Feasibility of Clinically Applied Frailty Instruments before Surgery: A Systematic Review and Meta-analysis | Aucoin, S. D. Hao, M. Sohi, R. Shaw, J. Bentov, I. Walker, D. McIsaac, D. I. | Anesthesiology | 2020 |
Aged |
Could COVID delirium bring on dementia? | Arnold, C. | Nature | 2020 |
COVID-19/ complications/epidemiology/ psychology |
Neighborhood-Level Social Disadvantage and Risk of Delirium Following Major Surgery | Arias, F. Chen, F. Fong, T. G. Shiff, H. Alegria, M. Marcantonio, E. R. Gou, Y. Jones, R. N. Travison, T. G. Schmitt, E. M. Kind, A. J. H. Inouye, S. K. | J Am Geriatr Soc | 2020 |
Area Deprivation Index |
Delirium is independently associated with early mortality in elderly patients starting hemodialysis | Arai, Y. Shioji, S. Tanaka, H. Kondo, I. Sakamoto, E. Suzuki, M. Katagiri, D. Tada, M. Hinoshita, F. | Clin Exp Nephrol | 2020 |
Chronic kidney disease |
COVID-19 inpatients with psychiatric disorders: Real-world clinical recommendations from an expert team in consultation-liaison psychiatry | Anmella, G. Arbelo, N. Fico, G. Murru, A. Llach, C. D. Madero, S. Gomes-da-Costa, S. Imaz, M. L. López-Pelayo, H. Vieta, E. Pintor, L. | J Affect Disord | 2020 |
Aged |
Relationship Between Intensive Care Unit Delirium Severity and 2-Year Mortality and Health Care Utilization | Andrews, P. S. Wang, S. Perkins, A. J. Gao, S. Khan, S. Lindroth, H. Boustani, M. Khan, B. | American journal of critical care : an official publication, American Association of Critical-Care Nurses | 2020 |
adult |
Impact of a Pharmacist-Led Intensive Care Unit Sleep Improvement Protocol on Sleep Duration and Quality | Andrews, J. L. Louzon, P. R. Torres, X. Pyles, E. Ali, M. H. Du, Y. Devlin, J. W. | Ann Pharmacother | 2020 |
activity tracker |
A Case of Concurrent Delirium and Catatonia in a Woman With Coronavirus Disease 2019 | Amouri, J. Andrews, P. S. Heckers, S. Ely, E. W. Wilson, J. E. | Psychosomatics | 2020 | |
Delirium pathway: a North Hampshire experience | Al-Rawi, Y. A. | Progress in Neurology and Psychiatry | 2020 |
aged |
Incidence and risk factors for acute delirium in older patients with a hip fracture: A retrospective cohort study | Aldwikat, R. K. Manias, E. Nicholson, P. | Nurs Health Sci | 2020 |
hip fracture |
Delirium, insulin-like growth factor I, growth hormone in older inpatients | Adamis, D. Coada, I. Eikelenboom, P. Chu, C. S. Finn, K. Melvin, V. Williams, J. Meagher, D. J. McCarthy, G. | World J Psychiatry | 2020 |
Cognition |
Critical Review and Meta-Analysis of Postoperative Sedation after Adult Cardiac Surgery: Dexmedetomidine Versus Propofol | Abowali, H. A. Paganini, M. Enten, G. Elbadawi, A. Camporesi, E. M. | J Cardiothorac Vasc Anesth | 2020 |
adult open cardiac surgery |
Polypharmacy at admission prolongs length of hospitalization in gastrointestinal surgery patients | Abe, N. Kakamu, T. Kumagai, T. Hidaka, T. Masuishi, Y. Endo, S. Kasuga, H. Fukushima, T. | Geriatr Gerontol Int | 2020 |
Adult |
Stroke-related delirium | Al-Khaled, M. | Journal of the Neurological Sciences | 2021 |
article |
Practice Variability in Screening and Treating Pediatric Critical Illness Delirium: Survey | Aljabari, S. Carter, C. Waheed, S. Anderson, J. E. | Journal of Pediatric Intensive Care | 2020 |
child |
Perioperative complications of pediatric otorhinolaryngological operations | Aleksandrovich, Y. Rybianov, V. Pshenisnov, K. V. Razumov, S. | Saudi Journal of Anaesthesia | 2020 |
Complications ENT Heart rate variability Pediatric Perioperative |
Prevention as Intervention: Reducing Incident Delirium in Heart Failure | Albert, B. L. | Journal of doctoral nursing practice | 2019 |
acute heart failure |
The prevalence of prescribing medications associated with geriatric syndromes among discharged elderly patients | Akkawi, M. E. Taufek, N. H. M. Hadi, A. D. A. Nik Lah, N. N. N. F. | Journal of Pharmacy and Bioallied Sciences | 2020 |
Elderly patients Geriatric Syndromes Medication prescribing |
Incidence and predictors of delirium after cardiac arrest – A retrospective registry | Aicher, N. Jäckel, M. Faye, C. Wengenmayer, T. Bode, C. Staudacher, D. L. | Resuscitation | 2020 |
noradrenalin |
Is ketamine safe for the pre-hospital sedation of patients with excited delirium secondary to sympathomimetic toxicity? | Adams, Y. | Australasian Journal of Paramedicine | 2019 |
adrenergic receptor stimulating agent |
Prospective, multi-centric benchmark study assessing delirium: prevalence, incidence and its correlates in hospitalized elderly Lebanese patients | Zrour, C. Haddad, R. Zoghbi, M. Kharsa, Z. Hijazi, M. Naja, W. | Aging Clin Exp Res | 2020 |
Correlated factors |
Knowledge and attitudes of adolescents with psychiatric disorders and their caregivers towards electroconvulsive therapy in China | Zong, Q. Q. Qi, H. Wang, Y. Y. Zhang, C. Balbuena, L. Ungvari, G. S. An, F. R. Xiang, Y. T. | Asian Journal of Psychiatry | 2020 |
adolescent |
Does postoperative delirium following elective noncardiac surgery predict long-term mortality? | Ziman, N. Sands, L. P. Tang, C. Zhu, J. Leung, J. M. | Age Ageing | 2020 |
long-term mortality |
Anxiety administrated by dexmedetomidine to prevent new-onset of postoperative atrial fibrillation in patients undergoing off-pump coronary artery bypass graft | Zi, J. Fan, Y. Dong, C. Zhao, Y. Li, D. Tan, Q. | International Heart Journal | 2020 |
1800014314 |
Assessment of Melatonergics in Prevention of Delirium: A Systematic Review and Meta-Analysis | Zhu, Y. Jiang, Z. Huang, H. Li, W. Ren, C. Yao, R. Wang, Y. Yao, Y. Li, W. Du, B. Xi, X. | Front Neurol | 2020 |
critical care medicine |
Geriatric Nutritional Risk Index can predict postoperative delirium and hospital length of stay in elderly patients undergoing non-cardiac surgery | Zhao, Y. Xia, X. Xie, D. Liao, Y. Wang, Y. Chen, L. Ge, N. Yue, J. | Geriatr Gerontol Int | 2020 |
Geriatric Nutritional Risk Index |
The geriatric nutrition risk index versus the mini-nutritional assessment short form in predicting postoperative delirium and hospital length of stay among older non-cardiac surgical patients: a prospective cohort study | Zhao, Y. Ge, N. Xie, D. Gao, L. Wang, Y. Liao, Y. Yue, J. | BMC Geriatr | 2020 |
Geriatric nutritional risk index |
Perioperative Multicomponent Interdisciplinary Program Reduces Delirium Incidence in Elderly Patients With Hip Fracture | Zhao, X. Yuan, W. | J Am Psychiatr Nurses Assoc | 2020 |
delirium |
Emergence delirium is associated with increased postoperative delirium in elderly: a prospective observational study | Zhang, Y. He, S. T. Nie, B. Li, X. Y. Wang, D. X. | J Anesth | 2020 |
Elderly |
S100β as a potential biomarker of incident delirium: a systematic review and meta-analysis | Zhang, X. Lyu, Y. Wang, D. | Minerva Anestesiol | 2020 | |
Effects of Dexmedetomidine on Postoperative Delirium and Expression of IL-1β, IL-6, and TNF-α in Elderly Patients After Hip Fracture Operation | Zhang, W. Wang, T. Wang, G. Yang, M. Zhou, Y. Yuan, Y. | Front Pharmacol | 2020 |
dexmedetomidine |
Nomogram Model for Predicting Risk of Postoperative Delirium After Deep Brain Stimulation Surgery in Patients Older Than 50 Years with Parkinson Disease | Zhan, L. Wang, X. Q. Zhang, L. X. | World Neurosurg | 2020 |
Advanced age |
Combining Ultrafast Anaesthesia and Minimal Invasive Implantation in HeartMate 3: A Pilot Study | Zayat, R. Ahmad, U. Twarie, L. Moza, A. Schaelte, G. Allham, O. Haneya, A. Khattab, M. Schnoering, H. Autschbach, R. | The Journal of heart and lung transplantation | 2020 |
adult |
Exosome α-Synuclein Release in Plasma May be Associated With Postoperative Delirium in Hip Fracture Patients | Yuan, Y. Li, Z. Yang, N. Han, Y. Ji, X. Han, D. Wang, X. Li, Y. Liu, T. Yuan, F. He, J. Liu, Y. Ni, C. Zou, P. Wang, G. Guo, X. Zhou, Y. | Front Aging Neurosci | 2020 |
exosome |
A multicentre, pragmatic, cluster randomised, controlled feasibility trial of the POD system of care | Young, J. Green, J. Farrin, A. Collinson, M. Hartley, S. Smith, J. Teale, E. Siddiqi, N. Inouye, S. K. | Age Ageing | 2020 |
delirium |
Association of Reversal of Anticoagulation Preoperatively on 30-Day Mortality and Outcomes for Hip Fracture Surgery | Yoo, M. S. Zhu, S. Jiang, S. F. Hammer, H. L. McBride, W. J. McCarthy, C. M. Green, C. E. Ananias, M. P. | American Journal of Medicine | 2020 |
adult |
Perioperative Complications and Prognosis of Curative Surgical Resection for Spinal Metastases in Elderly Patients | Yonezawa, N. Murakami, H. Demura, S. Kato, S. Yoshioka, K. Shinmura, K. Yokogawa, N. Shimizu, T. Oku, N. Kitagawa, R. Handa, M. Annen, R. Kurokawa, Y. Tsuchiya, H. | World Neurosurgery | 2020 |
titanium cage |
Risk factors for delirium in intensive care unit and its duration | Yanyan, L. Dajiang, Y. Xiaoya, L. Shao, W. | Zhonghua Wei Zhong Bing Ji Jiu Yi Xue | 2020 |
sedative agent |
Melatonergic agents in the prevention of delirium: A network meta-analysis of randomized controlled trials | Yang, C. P. Tseng, P. T. Pei-Chen Chang, J. Su, H. Satyanarayanan, S. K. Su, K. P. | Sleep Med Rev | 2020 |
Delirium |
Oxycodone preemptive analgesia after endoscopic plasma total adenotonsillectomy in children a randomized controlled trial | Wu, J. Gui, Q. Wang, J. Ye, J. Xia, Z. Wang, S. Liu, F. Kong, F. Zhong, L. | Medicine (United States) | 2020 |
ChiCTR-INR-16009116 |
Delirium screening practice in specialist palliative care units: a survey | Woodhouse, R. Siddiqi, N. Boland, J. W. Featherstone, I. Johnson, M. J. | BMJ Support Palliat Care | 2020 |
delirium |
Movements and trends in intensive care pain treatment and sedation: What matters to the patient? | Wøien, H. | J Clin Nurs | 2020 |
Adult |
Quetiapine therapy in critically injured trauma patients is associated with an increased risk of pulmonary complications | Wessels, L. E. Wallace, J. D. Calvo, R. Y. Levko, T. Bowie, J. M. Butler, W. J. Bansal, V. Sise, C. B. Martin, M. J. Sise, M. J. | Am J Surg | 2020 |
Antipsychotic Agents/ adverse effects |
Combined non-intubated anaesthesia and paravertebral nerve block in comparison with intubated anaesthesia in children undergoing video-assisted thoracic surgery | Wei, W. Fan, Y. Liu, W. Zhao, T. Tian, H. Xu, Y. Tan, Y. Song, X. Ma, D. | Acta Anaesthesiol Scand | 2020 | |
The occurrence and timing of delirium in acute care hospitalizations in the last year of life: A population-based retrospective cohort study | Webber, C. Watt, C. L. Bush, S. H. Lawlor, P. G. Talarico, R. Tanuseputro, P. | Palliat Med | 2020 |
Delirium |
Frailty screening in hospitalised older adults: How does the brief Dutch National Safety Management Program perform compared to a more extensive approach? | Warnier, R. M. J. van Rossum, E. van Kuijk, S. M. J. Magdelijns, F. Schols, Jmga Kempen, Gijm | J Clin Nurs | 2020 |
Aged |
Predicting postoperative delirium after microvascular decompression surgery with machine learning | Wang, Y. Lei, L. Ji, M. Tong, J. Zhou, C. M. Yang, J. J. | J Clin Anesth | 2020 |
Machine learning |
Propensity score-adjusted three-component mixture model for drug-drug interaction data mining in FDA Adverse Event Reporting System | Wang, X. Li, L. Wang, L. Feng, W. Zhang, P. | Statistics in Medicine | 2020 |
amfebutamone |
Comparison between Dexmedetomidine and Midazolam for Sedation in Patients with Intubation after Oral and Maxillofacial Surgery | Wang, L. Zhang, T. Huang, L. Peng, W. | Biomed Res Int | 2020 | |
Comparison of Intranasal Dexmedetomidine and Oral Midazolam for Premedication in Pediatric Dental Patients under General Anesthesia: A Randomised Clinical Trial | Wang, L. Huang, L. Zhang, T. Peng, W. | Biomed Res Int | 2020 | |
Accelerated magnetic seizure therapy (aMST) for treatment of major depressive disorder: A pilot study | Wang, J. Vila-Rodriguez, F. Ge, R. Gao, S. Gregory, E. Jiang, W. Yang, C. Wang, G. | J Affect Disord | 2020 |
Cognition |
Development and validation of the delirium risk assessment score (DRAS) | Vreeswijk, R. Kalisvaart, I. Maier, A. B. Kalisvaart, K. J. | Eur Geriatr Med | 2020 |
Delirium |
Development and validation of the delirium risk assessment score (DRAS) | Vreeswijk, R. Kalisvaart, I. Maier, A. B. Kalisvaart, K. J. | Eur Geriatr Med | 2020 |
Delirium |
Hospital readmission following transjugular intrahepatic portosystemic shunt: A 14-year single-center experience | Vozzo, C. F. Singh, T. Bullen, J. Sarvepalli, S. McCullough, A. Kapoor, B. | Gastroenterology Report | 2020 |
politef implant |
Anticholinergic drug exposure at intensive care unit admission affects the occurrence of delirium. A prospective cohort study | Vondeling, A. M. Knol, W. Egberts, T. C. G. Slooter, A. J. C. | Eur J Intern Med | 2020 |
Anticholinergics |
Delirium Screening in Neurocritical Care and Stroke Unit Patients: A Pilot Study on the Influence of Neurological Deficits on CAM-ICU and ICDSC Outcome | von Hofen-Hohloch, J. Awissus, C. Fischer, M. M. Michalski, D. Rumpf, J. J. Classen, J. | Neurocrit Care | 2020 |
Cam-icu |
Intensive Care Unit Delirium in Surgical Patients Is Associated with Upregulation in Tryptophan Metabolism | Voils, S. A. Shoulders, B. R. Singh, S. Solberg, L. M. Garrett, T. J. Frye, R. F. | Pharmacotherapy | 2020 |
critical care |
Vitamin D and Postoperative Delirium After Coronary Artery Bypass Grafting: A Prospective Cohort Study | Velayati, A. Vahdat Shariatpanahi, M. Dehghan, S. Zayeri, F. Vahdat Shariatpanahi, Z. | Journal of Cardiothoracic and Vascular Anesthesia | 2020 |
adult |
New Delirium Severity Indicators: Generation and Internal Validation in the Better Assessment of Illness (BASIL) Study | Vasunilashorn, S. M. Schulman-Green, D. Tommet, D. Fong, T. G. Hshieh, T. T. Marcantonio, E. R. Metzger, E. D. Schmitt, E. M. Tabloski, P. A. Travison, T. G. Gou, Y. Helfand, B. Inouye, S. K. Jones, R. N. | Dement Geriatr Cogn Disord | 2020 |
Delirium |
A New Severity Scoring Scale for the 3-Minute Confusion Assessment Method (3D-CAM) | Vasunilashorn, S. M. Devinney, M. J. Acker, L. Jung, Y. Ngo, L. Cooter, M. Huang, R. Marcantonio, E. R. Berger, M. | J Am Geriatr Soc | 2020 | |
Use of a digital delirium pathway and quality improvement to improve delirium detection in the emergency department and outcomes in an acute hospital | Vardy, E. Collins, N. Grover, U. Thompson, R. Bagnall, A. Clarke, G. Heywood, S. Thompson, B. Wintle, L. Nutt, L. Hulme, S. | Age Ageing | 2020 |
acute |
Registration of attentional function as a predictor of incident delirium (the RAPID study) | van Zuylen, M. L. Hermanides, J. Ten Hoope, W. Preckel, B. van de Beek, D. van Gool, W. A. Schoenmaker, N. | Alzheimers Dement (N Y) | 2020 |
attentional function |
Predisposition for delirium and EEG characteristics | van Montfort, S. J. T. van Dellen, E. Wattel, L. L. Kant, I. M. J. Numan, T. Stam, C. J. Slooter, A. J. C. | Clin Neurophysiol | 2020 |
Delirium |
Geriatric assessment in the prediction of delirium and long-term survival after transcatheter aortic valve implantation | van der Wulp, K. van Wely, M. H. Schoon, Y. Vart, P. Olde Rikkert, M. G. M. Morshuis, W. J. van Royen, N. Verkroost, M. W. A. Gehlmann, H. R. Van Garsse, L. A. F. M. Kievit, P. C. | Journal of Thoracic and Cardiovascular Surgery | 2020 |
aged |
Complications with focus on delirium during hospital stay related to femoral nerve block compared to conventional pain management among patients with hip fracture – A randomised controlled trial | Unneby, A. Svensson, P. O. Gustafson, P. Y. Lindgren, A. P. B. M. Bergström, U. Olofsson, P. B. | Injury | 2020 |
aged |
Preoperative Vitamin D Level is Associated with Postoperative Delirium After Cardiac Surgery in Patients Over 65 Years of Age | Tumer, N. B. Tekeli Kunt, A. Gunaydin, S. Ozisik, K. | Heart Surg Forum | 2020 | |
Epileptic seizure discharges in patients after open chamber cardiac surgery—a prospective prevalence pilot study using continuous electroencephalography | Tschernatsch, M. Juenemann, M. Alhaidar, F. El Shazly, J. Butz, M. Meyer, M. Gerriets, T. Schönburg, M. Schramm, P. | Intensive Care Medicine | 2020 |
adult |
Pharmacogenomic response of low dose haloperidol in critically ill adults with delirium | Trogrlić, Z. van der Jagt, M. Osse, R. J. Devlin, J. W. Nieboer, D. Koch, B. C. P. van Schaik, R. H. N. Hunfeld, N. G. M. | J Crit Care | 2020 |
Delirium |
The Impact of Music and Noise-Cancellation on Sedation Requirements During Total Knee Replacement: A Randomized Controlled Trial | Tran, B. W. Nowrouz, M. Y. Dhillon, S. K. Xie, K. K. Breslin, K. M. Golladay, G. J. | Geriatr Orthop Surg Rehabil | 2020 |
acute pain medicine |
The Prevalence and Impact of Undiagnosed Mild Cognitive Impairment in Elderly Patients Undergoing Thoracic Surgery: A Prospective Cohort Study | Tong, C. Huang, C. Wu, J. Xu, M. Cao, H. | J Cardiothorac Vasc Anesth | 2020 |
Mild cognitive impairment |
Development of a Palliative Care Toolkit for the COVID-19 Pandemic | Thomas, J. D. Leiter, R. E. Abrahm, J. L. Shameklis, J. C. Kiser, S. B. Gelfand, S. L. Sciacca, K. R. Reville, B. Siegert, C. A. Zhang, H. Lai, L. Sato, R. Smith, L. N. Kamdar, M. M. Greco, L. Lee, K. A. Tulsky, J. A. Lawton, A. J. | Journal of pain and symptom management | 2020 |
adult |
Interventions to Improve Clinical Outcomes in Older Adults Admitted to a Surgical Service: A Systematic Review and Meta-analysis | Thillainadesan, J. Yumol, M. F. Hilmer, S. Aitken, S. J. Naganathan, V. | J Am Med Dir Assoc | 2020 |
Aging |
Timeliness of care and adverse event profile in children undergoing general anesthesia or sedation for MRI: An observational prospective cohort study | Thampi, S. Jose, R. Kothandan, P. Jiwanmall, M. Rai, E. | Saudi Journal of Anaesthesia | 2020 |
laryngeal mask |