What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Delirium in Meningitis and Encephalitis: Emergence and Prediction in a 6-Year Cohort
- Authors
- Dittrich, T. Marsch, S. Rüegg, S. De Marchis, G. M. Tschudin-Sutter, S. Sutter, R.
- Year
- 2020
- Journal
- J Intensive Care Med
- Abstract
BACKGROUND/OBJECTIVE: Data regarding delirium in patients presenting with infections of the central nervous system, such as meningitis and/or encephalitis (ME), are scarce. We aimed to determine the frequency and early predictors of delirium in the acute phase of ME. METHODS: We assessed clinical, radiologic, and laboratory data of patients with ME at a Swiss academic medical center from 2011 to 2017. The highest Intensive Care Delirium Screening Checklist (ICDSC) score was assessed within 24 hours around lumbar puncture. Multivariable logistic regression was performed to identify predictors of delirium (ICDSC ≥4). RESULTS: Among 330 patients with ME, infectious pathogens were identified in 41%. An ICDSC >1 was found in 28% with and 19% without identified infectious pathogens. Delirium was diagnosed in 18% with and 14% without infectious pathogens and significantly associated with prolonged in-hospital treatment and mechanical ventilation, more frequent administration of neuroleptics and anesthetics (in 96% with delirium vs 35% without), complications, and less recovery to premorbid functional baseline. Low serum albumin at presentation was the only independent predictor of delirium (area under the receiver-operating curve [AUROC] = 0.792) in patients with pathogens. In patients with infections, the AUROC was smallest for encephalitis (AUROC = 0.641) and larger for patients with meningeal infections (meningitis AUROC = 0.807; meningoencephalitis AUROC = 0.896). CONCLUSIONS: Delirium in the context of ME is seen in almost every fifth patient and linked to prolonged treatment, complications, and incomplete recovery. Among clinical, radiologic, and laboratory parameters, the good calibration and discrimination of low albumin serum concentrations for the prediction of delirium in patients with ME seem promising, especially if meninges are affected.
- PMID
- Keywords
delirium
encephalitis
meningitis
meningoencephalitis
neurocritical care
- Page(s)
- Volume
- Issue
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| Association between glucose variability and postoperative delirium in acute aortic dissection patients: an observational study | Lin, Y. J. Lin, L. Y. Peng, Y. C. Zhang, H. R. Chen, L. W. Huang, X. Z. Chen, Q. | J Cardiothorac Surg | 2021 |
Acute Disease |
| Frailty is associated with a higher risk of developing delirium and cognitive impairment among patients with diabetic kidney disease: A longitudinal population-based cohort study | Lee, S. Y. Wang, J. Chao, C. T. Chien, K. L. Huang, J. W. | Diabet Med | 2021 |
chronic kidney disease |
| Multi-Component Care Bundle in Geriatric Fracture Hip for Reducing Post-Operative Delirium | Lam, D. M. H. Wang, C. Lee, A. K. H. Chung, Y. F. Lau, T. W. Fang, C. Leung, F. Chan, T. C. W. | Geriatr Orthop Surg Rehabil | 2021 |
delirium |
| Occurrence of Delirium during ECMO Therapy in a Critical Care Unit in Poland-A Cross-Sectional Pilot Study | Krupa, S. Friganovic, A. Mędrzycka-Dąbrowska, W. | Int J Environ Res Public Health | 2021 |
Critical Care |
| Steroids to reduce the impact on delirium (STRIDE): a double-blind, randomised, placebo-controlled feasibility trial of pre-operative dexamethasone in people with hip fracture | Kluger, M. T. Skarin, M. Collier, J. Rice, D. A. McNair, P. J. Seow, M. Y. Connolly, M. J. | Anaesthesia | 2021 |
delirium |
| Elevated plasma levels of galectin-3 binding protein are associated with post-stroke delirium - A pilot study | Klimiec-Moskal, E. Pasinska, P. Kowalska, K. Klimkowicz-Mrowiec, A. Pera, J. Slowik, A. Dziedzic, T. | J Neuroimmunol | 2021 |
Delirium |
| Postoperative delirium after cardiac surgery of elderly patients as an independent risk factor for prolonged length of stay in intensive care unit and in hospital | Kirfel, A. Menzenbach, J. Guttenthaler, V. Feggeler, J. Mayr, A. Coburn, M. Wittmann, M. | Aging Clin Exp Res | 2021 |
Cardiac surgery |
| ED-DEL: Development of a change package and toolkit for delirium in the emergency department | Kennedy, M. Webb, M. Gartaganis, S. Hwang, U. Biese, K. Stuck, A. Lesser, A. Hshieh, T. Inouye, S. K. | J Am Coll Emerg Physicians Open | 2021 |
aging |
| Elevated Monocyte Chemoattractant Protein-1 as the Independent Risk Factor of Delirium after Cardiac Surgery. A Prospective Cohort Study | Kaźmierski, J. Miler, P. Pawlak, A. Jerczyńska, H. Woźniak, J. Frankowska, E. Brzezińska, A. Woźniak, K. Krejca, M. Wilczyński, M. | J Clin Med | 2021 |
cardiac surgery |
| Prevalence of and factors associated with physical restraint use in the intensive care unit: a multicenter prospective observational study in Japan | Kawai, Y. Hamamoto, M. Miura, A. Yamaguchi, M. Masuda, Y. Iwata, M. Kanbe, M. Ikematsu, Y. | Intern Emerg Med | 2021 |
Associated factors |
| Added value of anxiolytic benzodiazepines in predictive models on severe delirium in patients with acute decompensated heart failure: A retrospective analysis | Kawada, K. Fukuda, H. Kubo, T. Ohta, T. Ishida, T. Morisawa, S. Kawazoe, T. Okamoto, M. Fujita, H. Jobu, K. Morita, Y. Ueba, T. Kitaoka, H. Miyamura, M. | PLoS One | 2021 | |
| Sagittal alignment changes and postoperative complications following surgery for adult spinal deformity in patients with Parkinson's disease: a multi-institutional retrospective cohort study | Kawabata, A. Yoshii, T. Sakai, K. Hirai, T. Yuasa, M. Inose, H. Matsukura, Y. Morishita, S. Tomori, M. Torigoe, I. Kusano, K. Otani, K. Arai, Y. Shindo, S. Okawa, A. | BMC Musculoskelet Disord | 2021 |
Follow-Up Studies |
| Factors associated with post-electroconvulsive therapy delirium: A retrospective chart review study | Jo, Y. T. Joo, S. W. Lee, J. Joo, Y. H. | Medicine (Baltimore) | 2021 |
Adult |
| Association of Delirium during Critical Illness With Mortality: Multicenter Prospective Cohort Study | Hughes, C. G. Hayhurst, C. J. Pandharipande, P. P. Shotwell, M. S. Feng, X. Wilson, J. E. Brummel, N. E. Girard, T. D. Jackson, J. C. Ely, E. W. Patel, M. B. | Anesth Analg | 2021 | |
| Validating the Mandarin version of the Memorial delirium assessment scale in general medical hospital patients | Hu, C. H. Chiu, Y. C. Liu, S. I. Ko, K. T. | Asia Pac Psychiatry | 2021 |
confusion assessment method |
| How do delirium motor subtypes differ in phenomenology and contributory aetiology? a cross-sectional, multisite study of liaison psychiatry and palliative care patients | Glynn, K. McKenna, F. Lally, K. O'Donnell, M. Grover, S. Chakrabarti, S. Avasthi, A. Mattoo, S. K. Sharma, A. Gosh, A. Shah, R. Hickey, D. Fitzgerald, J. Davis, B. O'Regan, N. Adamis, D. Williams, O. Awan, F. Dunne, C. Cullen, W. McInerney, S. McFarland, | BMJ Open | 2021 |
Adult |
| Frailty, post-operative delirium and functional status at discharge in patients with hip fracture | Gandossi, C. M. Zambon, A. Oliveri, G. Codognola, M. Szabo, H. Cazzulani, I. Ferrara, M. C. Mottadelli, C. Galeazzi, M. Amoroso, I. Zarcone, C. Principato, G. Corsi, M. Mazzola, P. Zatti, G. Foti, G. Bellelli, G. | Int J Geriatr Psychiatry | 2021 |
delirium |
| The Safety and Efficacy Evaluation of Dexmedetomidine for Procedural Sedation and Postoperative Behaviors in Pediatric Populations: A Systematic Review and Meta-analysis | Gan, L. Zhao, X. Chen, X. | Ann Pharmacother | 2021 |
delirium |
| Association between frailty and postoperative delirium: a meta-analysis of cohort study | Fu, D. Tan, X. Zhang, M. Chen, L. Yang, J. | Aging Clin Exp Res | 2021 |
Cohort studies |
| Incidence and factors associated with delirium in children in a single pediatric intensive care unit in Brazil | Flores, A. E. R. Oura, K. H. U. Rocha, P. K. Belela-Anacleto, A. S. C. Kusahara, D. M. | J Pediatr Nurs | 2021 |
Delirium |
| Long-Term Outcomes in Intensive Care Unit Patients with Delirium: A Population-Based Cohort Study | Fiest, K. M. Soo, A. Hee Lee, C. Niven, D. J. Ely, E. W. Doig, C. J. Stelfox, H. T. | Am J Respir Crit Care Med | 2021 |
critical care |
| Impact of Religiosity on Delirium Severity Among Critically Ill Shi'a Muslims: A Prospective Multi-Center Observational Study | Farzanegan, B. Elkhatib, T. H. M. Elgazzar, A. E. Moghaddam, K. G. Torkaman, M. Zarkesh, M. Goharani, R. Bashar, F. R. Hajiesmaeili, M. Shojaei, S. Madani, S. J. Vahedian-Azimi, A. Hatamian, S. Mosavinasab, S. M. M. Khoshfetrat, M. Khatir, A. K. Miller, A | J Relig Health | 2021 |
Critical Illness |
| Depression as a predictor of postoperative delirium after cardiac surgery: a systematic review and meta-analysis | Falk, A. Kåhlin, J. Nymark, C. Hultgren, R. Stenman, M. | Interact Cardiovasc Thorac Surg | 2021 |
Cardiac surgery |
| The delirium screening tool 4AT in routine clinical practice: prediction of mortality, sensitivity and specificity | Evensen, S. Hylen Ranhoff, A. Lydersen, S. Saltvedt, I. | Eur Geriatr Med | 2021 |
4at |
| Delirium and Associated Length of Stay and Costs in Critically Ill Patients | Dziegielewski, C. Skead, C. Canturk, T. Webber, C. Fernando, S. M. Thompson, L. H. Foster, M. Ristovic, V. Lawlor, P. G. Chaudhuri, D. Dave, C. Herritt, B. Bush, S. H. Kanji, S. Tanuseputro, P. Thavorn, K. Rosenberg, E. Kyeremanteng, K. | Crit Care Res Pract | 2021 | |
| Opioid Use Increases the Risk of Delirium in Critically Ill Adults Independently of Pain | Duprey, M. S. Dijkstra-Kersten, S. M. A. Zaal, I. J. Briesacher, B. A. Saczynski, J. S. Griffith, J. L. Devlin, J. W. Slooter, A. J. C. | Am J Respir Crit Care Med | 2021 |
delirium |
| Association Between Incident Delirium Treatment With Haloperidol and Mortality in Critically Ill Adults | uprey, M. S. Devlin, J. W. van der Hoeven, J. G. Pickkers, P. Briesacher, B. A. Saczynski, J. S. Griffith, J. L. van den Boogaard, M. | Crit Care Med | 2021 | |
| Descriptive analysis of the unwarranted continuation of antipsychotics for the management of ICU delirium during transitions of care: A multicenter evaluation across New Jersey | Dixit, D. Andrews, L. B. Radparvar, S. Adams, C. Kumar, S. T. Cardinale, M. | Am J Health Syst Pharm | 2021 |
ICU delirium |
| Cluster nursing can reduce postoperative delirium and improve the negative emotions and quality of life of elderly ICU patients | Di, J. Wang, X. Chen, J. | Am J Transl Res | 2021 |
Cluster nursing |
| Cluster nursing can reduce postoperative delirium and improve the negative emotions and quality of life of elderly ICU patients | Di, J. Wang, X. Chen, J. | Am J Transl Res | 2021 |
Cluster nursing |
| Influence of intraoperative and postoperative factors on the predictive capacity of the delirium risk model for cardiac surgery patients (DELIPRECAS): An observational multicentre study | de la Varga-Martínez, O. Gómez-Pesquera, E. Muñoz-Moreno, M. F. Marcos-Vidal, J. M. López-Gómez, A. Rodenas-Gómez, F. Ramasco, F. Álvarez-Refojo, F. Barón, M. S. Tamayo, E. Heredia-Rodríguez, M. Gómez-Sánchez, E. | J Clin Anesth | 2021 |
Cardiac Surgical Procedures/adverse effects |
| Older trauma patients are at high risk of delirium, especially those with underlying dementia or baseline frailty | Ní Chróinín D Francis, N. Wong, P. Kim, Y. D. Nham, S. D'Amours, S. | Trauma Surg Acute Care Open | 2021 |
cognition |
| The Impact of Monitoring Depth of Anesthesia and Nociception on Postoperative Cognitive Function in Adult Multiple Trauma Patients | Cotae, A. M. Ţigliş, M. Cobilinschi, C. Băetu, A. E. Iacob, D. M. Grinţescu, I. M. | Medicina (Kaunas) | 2021 |
Adult |
| Outcomes of trimodality CROSS regimen in older adults with locally advanced esophageal cancer | Cooper, L. Dezube, A. R. De León, L. E. Kucukak, S. Mazzola, E. Dumontier, C. Mamon, H. Enzinger, P. Jaklitsch, M. T. Frain, L. N. Wee, J. O. | Eur J Surg Oncol | 2021 |
Cross |
| Nursing intervention to prevent delirium in critically ill adults | Contreras, C. C. T. Páez-Esteban, A. N. Rincon-Romero, M. K. Carvajal, R. R. Herrera, M. M. Castillo, Ahdd | Rev Esc Enferm USP | 2021 | |
| Changes in Sedation Practices in Association with Delirium Screening in Infants After Cardiopulmonary Bypass | Chomat, M. R. Said, A. S. Mann, J. L. Wallendorf, M. Bickhaus, A. Figueroa, M. | Pediatr Cardiol | 2021 |
Cornell Assessment of Pediatric Delirium |
| Risk factors of postoperative delirium after cardiac surgery: a meta-analysis | Chen, H. Mo, L. Hu, H. Ou, Y. Luo, J. | J Cardiothorac Surg | 2021 |
Age Factors |
| Diagnosis of overweight or obese malnutrition spells DOOM for hip fracture patients: A prospective audit | Bell, J. J. Pulle, R. C. Lee, H. B. Ferrier, R. Crouch, A. Whitehouse, S. L. | Clin Nutr | 2021 |
Body mass index |
| Risk factors for delirium among hospitalized patients in Zambia | Mateyo, K. Yan, Y. Liu, D. Zuo, Y. Di Gravio, C. Thome, J. C. Riviello, E. D. Saylor, D. Ely, E. W. Heimburger, D. C. | PLoS One | 2021 | |
| Risk factors associated with treatment of hyperactive postoperative delirium in elderly patients following hip fracture surgery under regional anesthesia: a nationwide population-based study | Ahn, E. J. Bang, S. R. | Braz J Anesthesiol | 2021 |
Anesthesia |
| Incidence of delirium in the critical care unit and risk factors in the Central Region, Saudi Arabia | Abazid, R. M. Al-Harbi, S. A. Allihimy, A. S. Aldrewesh, D. A. Alkuraydis, S. A. Alhammad, I. M. Elbashir, A. Y. Widyan, A. M. Abohamr, S. I. | Saudi Med J | 2021 |
Saudi |
| The risk factors of postoperative delirium in patients with hip fracture: implication for clinical management | Xu, W. Ma, H. Li, W. Zhang, C. | BMC Musculoskelet Disord | 2021 |
Delirium/diagnosis/epidemiology/etiology |
| Nationwide mortality trends of delirium in Australia and the United States from 2006 to 2016 | Wu, H. Mach, J. Le Couteur, D. G. Hilmer, S. N. | Australas J Ageing | 2021 |
delirium |
| The Use of Near-Infrared Spectroscopy and/or Transcranial Doppler as Non-Invasive Markers of Cerebral Perfusion in Adult Sepsis Patients With Delirium: A Systematic Review | Wood, M. D. Boyd, J. G. Wood, N. Frank, J. Girard, T. D. Ross-White, A. Chopra, A. Foster, D. Griesdale, D. E. G. | J Intensive Care Med | 2021 |
cerebral autoregulation |
| Midazolam Premedication Immediately Before Surgery Is Not Associated With Early Postoperative Delirium | Wang, M. L. Min, J. Sands, L. P. Leung, J. M. | Anesth Analg | 2021 | |
| The Effect of a Quality Improvement Intervention on Sleep and Delirium in Critically Ill Patients in a Surgical ICU | Tonna, J. E. Dalton, A. Presson, A. P. Zhang, C. Colantuoni, E. Lander, K. Howard, S. Beynon, J. Kamdar, B. B. | Chest | 2021 |
critical care |
| Association between components of the delirium syndrome and outcomes in hospitalised adults: a systematic review and meta-analysis | Tieges, Z. Quinn, T. MacKenzie, L. Davis, D. Muniz-Terrera, G. MacLullich, A. M. J. Shenkin, S. D. | BMC Geriatr | 2021 |
Cognition |
| The Prognostic Performance of Frailty for Delirium and Functional Decline in Vascular Surgery Patients | Thillainadesan, J. Mudge, A. M. Aitken, S. J. Hilmer, S. N. Cullen, J. S. Yumol, M. F. Close, J. C. T. Norris, C. M. Kerdic, R. Naganathan, V. | J Am Geriatr Soc | 2021 |
delirium |
| Efficacy of quetiapine for delirium prevention in hospitalized older medical patients: a randomized double-blind controlled trial | Thanapluetiwong, S. Ruangritchankul, S. Sriwannopas, O. Chansirikarnjana, S. Ittasakul, P. Ngamkala, T. Sukumalin, L. Charernwat, P. Saranburut, K. Assavapokee, T. | BMC Geriatr | 2021 |
Aged |
| Effects of Slowness, Frailty, Insufficient Intake, and Delirium in Patients Following Cardiac Surgery: A Cohort Study | Teng, C. H. Hsu, R. B. Chi, N. H. Wang, S. S. Chen, Y. S. Chen, S. Y. Chen, C. C. | J Cardiovasc Nurs | 2021 | |
| Factors associated with the severity of delirium | Tachibana, M. Inada, T. Ichida, M. Kojima, S. Shioya, M. Wakayama, K. Ozaki, N. | Hum Psychopharmacol | 2021 |
Drs-r98 |
| Screening for delirium in the intensive care unit using eDIS-ICU - A purpose-designed app: A pilot study | Sutt, A. L. Flaws, D. Gunn, H. Eeles, E. Lye, I. Irvine, L. Patterson, S. Bagshaw, T. O'Luanaigh, C. Tronstad, O. Fraser, J. | Aust Crit Care | 2021 |
Delirium |
| Association Among Preoperative Cognitive Performance, Regional Cerebral Oxygen Saturation, and Postoperative Delirium in Older Portuguese Patients | Susano, M. J. Dias, M. Seixas, F. S. Vide, S. Grasfield, R. Abelha, F. J. Crosby, G. Culley, D. J. Amorim, P. | Anesth Analg | 2021 |
Age Factors |
| Sleep and circadian rhythm disturbances in intensive care unit (ICU)-acquired delirium: a case-control study | Sun, T. Sun, Y. Huang, X. Liu, J. Yang, J. Zhang, K. Kong, G. Han, F. Hao, D. Wang, X. | J Int Med Res | 2021 |
Adolescent |
| Terminal Delirium in Hospice: The Experiences and Perspectives of Caregivers Providing Care to Terminally Ill Patients in Home Settings | Soroka, J. T. Fling, K. J. Heibel, J. M. Kutcher, G. R. Ward, S. J. | Am J Hosp Palliat Care | 2021 |
caregivers |
| Estimates of Geriatric Delirium Frequency in Noncardiac Surgeries and Its Evaluation Across the Years: A Systematic Review and Meta-analysis | Silva, A. R. Regueira, P. Albuquerque, E. Baldeiras, I. Cardoso, A. L. Santana, I. Cerejeira, J. | J Am Med Dir Assoc | 2021 |
Delirium |
| The Effects of Bispectral Index-Guided Anesthesia on Postoperative Delirium in Elderly Patients: A Systematic Review and Meta-Analysis | Shan, W. Chen, B. Huang, L. Zhou, Y. | World Neurosurg | 2021 |
Bispectral index |
| Validation of the Delirium Diagnostic Tool-Provisional (DDT-Pro) in a skilled nursing facility and comparison to the 4 'A's test (4AT) | Sepúlveda, E. Bermúdez, E. González, D. Cotino, P. Viñuelas, E. Palma, J. Ciutat, M. Grau, I. Vilella, E. Trzepacz, P. T. Franco, J. G. | Gen Hosp Psychiatry | 2021 |
Delirium diagnosis |
| Evaluation of Delirium in Critically Ill Patients Prescribed Melatonin or Ramelteon | Romero, N. Dube, K. M. Lupi, K. E. DeGrado, J. R. | Ann Pharmacother | 2021 |
agitation |
| Delirium and delirium severity predict the trajectory of the Hierarchical Assessment of Balance and Mobility (HABAM) in hospitalised older people: findings from the DECIDE Study | Richardson, S. Murray, J. Davis, D. Stephan, B. C. M. Robinson, L. Brayne, C. Barnes, L. Parker, S. Sayer, A. Dodds, R. Allan, L. | J Gerontol A Biol Sci Med Sci | 2021 |
Epidemiology |
| Common biomarkers of physiologic stress and associations with delirium in patients with intracerebral hemorrhage | Reznik, M. E. Kalagara, R. Moody, S. Drake, J. Margolis, S. A. Cizginer, S. Mahta, A. Rao, S. S. Stretz, C. Wendell, L. C. Thompson, B. B. Asaad, W. F. Furie, K. L. Jones, R. N. Daiello, L. A. | J Crit Care | 2021 |
Biomarkers |
| Effects of Preoperative Anxiety on Postoperative Delirium in Elderly Patients Undergoing Elective Orthopedic Surgery: A Prospective Observational Cohort Study | Ren, A. Zhang, N. Zhu, H. Zhou, K. Cao, Y. Liu, J. | Clin Interv Aging | 2021 |
Aged |
| Hyperactive delirium in patients after non-traumatic subarachnoid hemorrhage | Reimann, F. Rinner, T. Lindner, A. Kofler, M. Ianosi, B. A. Schiefecker, A. J. Beer, R. Schmutzhard, E. Pfausler, B. Helbok, R. Rass, V. | J Crit Care | 2021 |
Critical care |
| Prescribing Practices of Valproic Acid for Agitation and Delirium in the Intensive Care Unit | Quinn, N. J. Hohlfelder, B. Wanek, M. R. Duggal, A. Torbic, H. | Ann Pharmacother | 2021 |
Aged |
| Delirium and Mortality in Coronavirus Disease 2019 (COVID-19) - A Systematic Review and Meta-analysis | Pranata, R. Huang, I. Lim, M. A. Yonas, E. Vania, R. Kuswardhani, R. A. T. | Arch Gerontol Geriatr | 2021 |
Aged Covid-19 |
| Dexmedetomidine vs. total intravenous anaesthesia in paediatric emergence delirium: A network meta-analysis | Petre, M. A. Levin, D. N. Englesakis, M. Maynes, J. T. Pechlivanoglou, P. Aoyama, K. | Eur J Anaesthesiol | 2021 | |
| Delirium prevalence in a Colombian hospital, association with geriatric syndromes and complications during hospitalization | Peralta-Cuervo, A. F. Garcia-Cifuentes, E. Castellanos-Perilla, N. Chavarro-Carvajal, D. A. Venegas-Sanabria, L. C. Cano-Gutiérrez, C. A. | Rev Esp Geriatr Gerontol | 2021 |
Aged |
| Anticholinergic load and delirium in end-of-life patients | Pasina, L. Rizzi, B. Nobili, A. Recchia, A. | Eur J Clin Pharmacol | 2021 |
Anticholinergic drugs |
| Patients, family members and providers perceive family-administered delirium detection tools in the adult ICU as feasible and of value to patient care and family member coping: a qualitative focus group study | Parsons Leigh, J. Krewulak, K. D. Zepeda, N. Farrier, C. E. Spence, K. L. Davidson, J. E. Stelfox, H. T. Fiest, K. M. | Can J Anaesth | 2021 |
Adaptation, Psychological |
| Serum melatonin concentration in critically ill patients randomized to sedation or non-sedation | Oxlund, J. Knudsen, T. Strøm, T. Lauridsen, J. T. Jennum, P. J. Toft, P. | Ann Intensive Care | 2021 |
Circadian |
| Depression predicts cognitive and functional decline one month after coronary artery bypass graft surgery (Neuropsychiatric Outcomes After Heart Surgery study) | Oldham, M. A. Lin, I. H. Hawkins, K. A. Li, F. Y. Yuh, D. D. Lee, H. B. | Int J Geriatr Psychiatry | 2021 |
Aged |
| Effect of deep neuromuscular blockade on serum cytokines and postoperative delirium in elderly patients undergoing total hip replacement: A prospective single-blind randomised controlled trial | Oh, C. S. Lim, H. Y. Jeon, H. J. Kim, T. H. Park, H. J. Piao, L. Kim, S. H. | Eur J Anaesthesiol | 2021 |
Aged |
| Cerebral autoregulation in the operating room and intensive care unit after cardiac surgery | Nakano, M. Nomura, Y. Whitman, G. Sussman, M. Schena, S. Kilic, A. Choi, C. W. Akiyoshi, K. Neufeld, K. J. Lawton, J. Colantuoni, E. Yamaguchi, A. Wen, M. Smielewski, P. Brady, K. Bush, B. Hogue, C. W. Brown, C. H. th | Br J Anaesth | 2021 |
Aged |
| Propofol plus low-dose dexmedetomidine infusion and postoperative delirium in older patients undergoing cardiac surgery | Momeni, M. Khalifa, C. Lemaire, G. Watremez, C. Tircoveanu, R. Van Dyck, M. Kahn, D. Rosal Martins, M. Mastrobuoni, S. De Kerchove, L. Zango, S. H. Jacquet, L. M. | Br J Anaesth | 2021 |
Aged |
| Delirium REduction after administration of melatonin in acute ischemic stroke (DREAMS): A propensity score-matched analysis | Mengel, A. Zurloh, J. Boßelmann, C. Brendel, B. Stadler, V. Sartor-Pfeiffer, J. Meisel, A. Fleischmann, R. Ziemann, U. Poli, S. Stefanou, M. I. | Eur J Neurol | 2021 |
delirium |
| Incidence, Risk Factors and Impact on Long-Term Outcome of Postoperative Delirium After Transcatheter Aortic Valve Replacement | Mauri, V. Reuter, K. Körber, M. I. Wienemann, H. Lee, S. Eghbalzadeh, K. Kuhn, E. Baldus, S. Kelm, M. Nickenig, G. Veulemans, V. Jansen, F. Adam, M. Rudolph, T. K. | Front Cardiovasc Med | 2021 |
Tavr |
| Predisposing and Precipitating Factors for Delirium in the Very Old (≥80 Years): A Prospective Cohort Study of 3,076 Patients | Marquetand, J. Bode, L. Fuchs, S. Ernst, J. von Känel, R. Boettger, S. | Gerontology | 2021 |
80 years |
| Delirium and Functional Recovery in Patients Discharged to Skilled Nursing Facilities After Hospitalization for Heart Failure | Madrigal, C. Kim, J. Jiang, L. Lafo, J. Bozzay, M. Primack, J. Correia, S. Erqou, S. Wu, W. C. Rudolph, J. L. | JAMA Netw Open | 2021 |
Activities of Daily Living |
| Prevalence of high-risk medications in patients enrolled in the Hospital Elder Life Program | Macias Tejada, J. A. Klumph, M. Heslin, K. Khan, A. Malone, M. L. | J Am Geriatr Soc | 2021 |
antipsychotics |
| Acupuncture Treatment of Delirium in Older Adults Hospitalized in Internal Medicine Departments: An Open-Label Pragmatic Randomized-Controlled Trial | Levy, I. Gavrieli, S. Hefer, T. Attias, S. Schiff, A. Oliven, R. Wisberg-Levi, S. Hanchinsky, R. Schiff, E. | J Geriatr Psychiatry Neurol | 2021 |
acupuncture |
| Impact of an orthogeriatric collaborative care model for older adults with hip fracture in a community hospital setting | Lee, J. C. Koo, K. Wong, E. K. C. Naqvi, R. Wong, C. L. | Can J Surg | 2021 | |
| Cardiac Delirium Index for Predicting the Occurrence of Postoperative Delirium in Adult Patients After Coronary Artery Bypass Grafting | Lechowicz, K. Szylińska, A. Listewnik, M. Drożdżal, S. Tomska, N. Rotter, I. Kotfis, K. | Clin Interv Aging | 2021 |
Aged |
| Delirium documentation in hospitalized pediatric patients with cancer | Lastrapes, K. Dang, M. Cassel, J. B. Orr, T. Proffitt, T. Del Fabbro, E. | Palliat Support Care | 2021 |
Delirium |
| Efficacy of two integrated geriatric care pathways for the treatment of hip fractures: a cross-cultural comparison | Kusen, J. Q. van der Vet, P. C. R. Wijdicks, F. J. G. Verleisdonk, Ejjm Link, B. C. Houwert, R. M. Knobe, M. van der Velde, D. Babst, R. Beeres, F. J. P. | Eur J Trauma Emerg Surg | 2021 |
Clinical pathway |
| Depressed mood, associated factors, and understanding of delirium among caregivers of patients with delirium | Kim, S. Y. Jhon, M. Kang, H. J. Lee, J. Y. Kim, S. W. Kim, J. M. Shin, I. S. | Int J Psychiatry Med | 2021 |
caregiver |
| Scheduled Prophylactic 6-Hourly IV AcetaminopheN to Prevent Postoperative Delirium in Older CaRdiac SurgicAl Patients (PANDORA): protocol for a multicentre randomised controlled trial | Khera, T. Mathur, P. A. Banner-Goodspeed, V. M. Narayanan, S. McGourty, M. Kelly, L. Palihnich, K. Novack, L. Davis, R. Talmor, D. Marcantonio, E. R. Subramaniam, B. | BMJ Open | 2021 |
Acetaminophen |
| Serum Biomarkers in Postoperative Delirium after Esophagectomy | Khan, S. H. Lindroth, H. Jawed, Y. Wang, S. Nasser, J. Seyffert, S. Naqvi, K. Perkins, A. J. Gao, S. Kesler, K. Khan, B. | Ann Thorac Surg | 2021 |
biomarkers |
| Drug-related problems of antipsychotics in treating delirium among elderly patients: A real-world observational study | Jenraumjit, R. Somboon, J. Chainan, S. Chuenchom, P. Wongpakaran, N. Wongpakaran, T. | J Clin Pharm Ther | 2021 |
antipsychotics |
| Effect of Melatonin on Delirium After on-Pump Coronary Artery Bypass Graft Surgery: A Randomized Clinical Trial | Javaherforoosh Zadeh, F. Janatmakan, F. Shafaeebejestan, E. Jorairahmadi, S | Iran J Med Sci | 2021 |
Delirium |
| A polysomnography study examining the association between sleep and postoperative delirium in older hospitalized cardiac surgical patients | Ibala, R. Mekonnen, J. Gitlin, J. Hahm, E. Y. Ethridge, B. R. Colon, K. M. Marota, S. Ortega, C. Pedemonte, J. C. Cobanaj, M. Chamadia, S. Qu, J. Gao, L. Barbieri, R. Akeju, O. | J Sleep Res | 2021 |
cardiac surgery |
| Delirium in older patients undergoing aortic valve replacement: incidence, predictors, and cognitive prognosis | Humbert, M. Büla, C. J. Muller, O. Krief, H. Monney, P. | BMC Geriatr | 2021 |
Activities of Daily Living |
| A clinical risk analysis of early post-operative delirium after laparoscopic colorectal cancer surgery in elderly patients: a retrospective study | Hiraki, M. Tanaka, T. Ishii, H. Sadashima, E. Miura, D. Sunami, T. Hanafusa, K. Sato, H. Kitahara, K. | Int J Colorectal Dis | 2021 |
Aged |
| Nurses' experiences of delirium and how to identify delirium-A qualitative study | Helgesen, A. K. Adan, Y. H. Dybvik Bjørglund, C. Weberg-Haugen, C. Johannessen, M. Åsmul Kristiansen, K. Vasskog Risan, E. Relusco, M. L. Skaarer-Heen, H. M. Sørensen, T. S. Vedå, L. Abrahamsen Grøndahl, V. | Nurs Open | 2021 |
Delirium/diagnosis |
| Preoperative Comparison of Three Anticholinergic Drug Scales in Older Adult Patients and Development of Postoperative Delirium: A Prospective Observational Study | Heinrich, M. Müller, A. Cvijan, A. Mörgeli, R. Kruppa, J. Winterer, G. Slooter, A. J. C. Spies, C. D. | Drugs Aging | 2021 | |
| Characterization of Nocturnal Neuroactive Medication Use and Related Sleep Documentation in Critically Ill Adults | Hamidi, A. Roberts, R. J. Weinhouse, G. L. Szumita, P. M. Degrado, J. R. Dube, K. M. Kovacevic, M. P. Choi, M. Sevinsky, R. Duprey, M. S. Devlin, J. W. | Crit Care Explor | 2021 |
antipsychotics |
| Optimal interval and duration of CAM-ICU assessments for delirium detection after cardiac surgery | Hamadnalla, H. Sessler, D. I. Troianos, C. A. Fang, J. Rivas, E. Ma, C. Mascha, E. J. Turan, A. | J Clin Anesth | 2021 |
Anesthesia |
| Is there evidence for using anticonvulsants in the prevention and/or treatment of delirium among older adults? | Gupta, A. Joshi, P. Bhattacharya, G. Lehman, M. Funaro, M. Tampi, D. J. Tampi, R. R. | Int Psychogeriatr | 2021 |
anticonvulsants |
| Is there evidence for using anticonvulsants in the prevention and/or treatment of delirium among older adults? | Gupta, A. Joshi, P. Bhattacharya, G. Lehman, M. Funaro, M. Tampi, D. J. Tampi, R. R. | Int Psychogeriatr | 2021 |
anticonvulsants |
| Association of CSF Alzheimer's disease biomarkers with postoperative delirium in older adults | Fong, T. G. Vasunilashorn, S. M. Gou, Y. Libermann, T. A. Dillon, S. Schmitt, E. Arnold, S. E. Kivisäkk, P. Carlyle, B. Oh, E. S. Vlassakov, K. Kunze, L. Hshieh, T. Jones, R. N. Marcantonio, E. R. Inouye, S. K. | Alzheimers Dement (N Y) | 2021 |
AD biomarkers |
| Impact of Delirium and Its Motor Subtypes on Stroke Outcomes | Fialho Silva, I. T. Assis Lopes, P. Timotio Almeida, T. Ramos, S. C. Caliman Fontes, A. T. Guimarães Silva, D. Martins Soares, C. Oliveira Carneiro, L. Souza, I. F. B. Ferreira Abreu, F. Nascimento Silva, G. Mascarenhas de Souza, L. Brito Pinheiro, T. de | Stroke | 2021 |
cognition |