Delirium Bibliography

Delirium Bibliography books graphicWhat is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!

How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.

Reference Information

Title
Delirium in Meningitis and Encephalitis: Emergence and Prediction in a 6-Year Cohort
Authors
Dittrich, T. Marsch, S. Rüegg, S. De Marchis, G. M. Tschudin-Sutter, S. Sutter, R.
Year
2020
Journal
J Intensive Care Med
Abstract

BACKGROUND/OBJECTIVE: Data regarding delirium in patients presenting with infections of the central nervous system, such as meningitis and/or encephalitis (ME), are scarce. We aimed to determine the frequency and early predictors of delirium in the acute phase of ME. METHODS: We assessed clinical, radiologic, and laboratory data of patients with ME at a Swiss academic medical center from 2011 to 2017. The highest Intensive Care Delirium Screening Checklist (ICDSC) score was assessed within 24 hours around lumbar puncture. Multivariable logistic regression was performed to identify predictors of delirium (ICDSC ≥4). RESULTS: Among 330 patients with ME, infectious pathogens were identified in 41%. An ICDSC >1 was found in 28% with and 19% without identified infectious pathogens. Delirium was diagnosed in 18% with and 14% without infectious pathogens and significantly associated with prolonged in-hospital treatment and mechanical ventilation, more frequent administration of neuroleptics and anesthetics (in 96% with delirium vs 35% without), complications, and less recovery to premorbid functional baseline. Low serum albumin at presentation was the only independent predictor of delirium (area under the receiver-operating curve [AUROC] = 0.792) in patients with pathogens. In patients with infections, the AUROC was smallest for encephalitis (AUROC = 0.641) and larger for patients with meningeal infections (meningitis AUROC = 0.807; meningoencephalitis AUROC = 0.896). CONCLUSIONS: Delirium in the context of ME is seen in almost every fifth patient and linked to prolonged treatment, complications, and incomplete recovery. Among clinical, radiologic, and laboratory parameters, the good calibration and discrimination of low albumin serum concentrations for the prediction of delirium in patients with ME seem promising, especially if meninges are affected.

PMID

32193987

Keywords

delirium
encephalitis
meningitis
meningoencephalitis
neurocritical care

Page(s)
Issue

Search:
Total Records Found: 6300, showing 100 per page
TitleAuthorsJournalYearKeywords
Association between glucose variability and postoperative delirium in acute aortic dissection patients: an observational study Lin, Y. J. Lin, L. Y. Peng, Y. C. Zhang, H. R. Chen, L. W. Huang, X. Z. Chen, Q. J Cardiothorac Surg 2021

Acute Disease
Adult
Aneurysm, Dissecting/blood/ surgery
Blood Glucose/ analysis
Cardiac Surgical Procedures/adverse effects
Cardiovascular Surgical Procedures/ adverse effects
Delirium/ blood/diagnosis/etiology
Female
Humans
Intensive Care Units
Length of Stay
Male
Middle Aged
Prognosis
Proportional Hazards Models
Prospective Studies
Risk Factors
Survival Analysis
Acute aortic dissection patient
Glucose variability
Postoperative delirium

Frailty is associated with a higher risk of developing delirium and cognitive impairment among patients with diabetic kidney disease: A longitudinal population-based cohort study Lee, S. Y. Wang, J. Chao, C. T. Chien, K. L. Huang, J. W. Diabet Med 2021

chronic kidney disease
cognitive impairment
delirium
diabetes mellitus
diabetic kidney disease
frail phenotype

Multi-Component Care Bundle in Geriatric Fracture Hip for Reducing Post-Operative Delirium Lam, D. M. H. Wang, C. Lee, A. K. H. Chung, Y. F. Lau, T. W. Fang, C. Leung, F. Chan, T. C. W. Geriatr Orthop Surg Rehabil 2021

delirium
fascia iliaca block
geriatric fracture hip
geriatric trauma
multi-component care bundle
postoperative delirium
ultrasound-guided fascia iliaca block

Occurrence of Delirium during ECMO Therapy in a Critical Care Unit in Poland-A Cross-Sectional Pilot Study Krupa, S. Friganovic, A. Mędrzycka-Dąbrowska, W. Int J Environ Res Public Health 2021

Critical Care
Cross-Sectional Studies
Delirium/epidemiology
Extracorporeal Membrane Oxygenation/adverse effects
Humans
Pilot Projects
Poland/epidemiology
delirium
extracorporeal membrane oxygenation

Steroids to reduce the impact on delirium (STRIDE): a double-blind, randomised, placebo-controlled feasibility trial of pre-operative dexamethasone in people with hip fracture Kluger, M. T. Skarin, M. Collier, J. Rice, D. A. McNair, P. J. Seow, M. Y. Connolly, M. J. Anaesthesia 2021

delirium
dexamethasone
hip fracture
prevention

Elevated plasma levels of galectin-3 binding protein are associated with post-stroke delirium - A pilot study Klimiec-Moskal, E. Pasinska, P. Kowalska, K. Klimkowicz-Mrowiec, A. Pera, J. Slowik, A. Dziedzic, T. J Neuroimmunol 2021

Delirium
Gal-3BP
Hmgb1
Inflammation
Ischemic stroke

Postoperative delirium after cardiac surgery of elderly patients as an independent risk factor for prolonged length of stay in intensive care unit and in hospital Kirfel, A. Menzenbach, J. Guttenthaler, V. Feggeler, J. Mayr, A. Coburn, M. Wittmann, M. Aging Clin Exp Res 2021

Cardiac surgery
Diagnosis of delirium
Elderly patients
Length of stay
Postoperative delirium

ED-DEL: Development of a change package and toolkit for delirium in the emergency department Kennedy, M. Webb, M. Gartaganis, S. Hwang, U. Biese, K. Stuck, A. Lesser, A. Hshieh, T. Inouye, S. K. J Am Coll Emerg Physicians Open 2021

aging
delirium
emergency department
geriatrics
organizational innovation
quality assurance
quality improvement

Elevated Monocyte Chemoattractant Protein-1 as the Independent Risk Factor of Delirium after Cardiac Surgery. A Prospective Cohort Study Kaźmierski, J. Miler, P. Pawlak, A. Jerczyńska, H. Woźniak, J. Frankowska, E. Brzezińska, A. Woźniak, K. Krejca, M. Wilczyński, M. J Clin Med 2021

cardiac surgery
coronary artery bypass grafting
delirium
high-sensitivity C-reactive protein
monocyte chemoattractant protein-1

Prevalence of and factors associated with physical restraint use in the intensive care unit: a multicenter prospective observational study in Japan Kawai, Y. Hamamoto, M. Miura, A. Yamaguchi, M. Masuda, Y. Iwata, M. Kanbe, M. Ikematsu, Y. Intern Emerg Med 2021

Associated factors
Intensive care unit (ICU)
Physical restraint
Prevalence

Added value of anxiolytic benzodiazepines in predictive models on severe delirium in patients with acute decompensated heart failure: A retrospective analysis Kawada, K. Fukuda, H. Kubo, T. Ohta, T. Ishida, T. Morisawa, S. Kawazoe, T. Okamoto, M. Fujita, H. Jobu, K. Morita, Y. Ueba, T. Kitaoka, H. Miyamura, M. PLoS One 2021
Sagittal alignment changes and postoperative complications following surgery for adult spinal deformity in patients with Parkinson's disease: a multi-institutional retrospective cohort study Kawabata, A. Yoshii, T. Sakai, K. Hirai, T. Yuasa, M. Inose, H. Matsukura, Y. Morishita, S. Tomori, M. Torigoe, I. Kusano, K. Otani, K. Arai, Y. Shindo, S. Okawa, A. BMC Musculoskelet Disord 2021

Follow-Up Studies
Humans
Parkinson Disease/complications/epidemiology
Postoperative Complications/diagnostic imaging/epidemiology/etiology
Retrospective Studies
Spinal Fusion/adverse effects
Adult spinal deformity
Parkinson’s disease
Postoperative complications
Radiographic parameters
Sagittal alignment
Sagittal vertical axis

Factors associated with post-electroconvulsive therapy delirium: A retrospective chart review study Jo, Y. T. Joo, S. W. Lee, J. Joo, Y. H. Medicine (Baltimore) 2021

Adult
Anesthetics/administration & dosage/ adverse effects
Case-Control Studies
Delirium/ etiology
Electroconvulsive Therapy/ adverse effects/methods
Etomidate/administration & dosage/ adverse effects
Female
Humans
Male
Middle Aged
Retrospective Studies

Association of Delirium during Critical Illness With Mortality: Multicenter Prospective Cohort Study Hughes, C. G. Hayhurst, C. J. Pandharipande, P. P. Shotwell, M. S. Feng, X. Wilson, J. E. Brummel, N. E. Girard, T. D. Jackson, J. C. Ely, E. W. Patel, M. B. Anesth Analg 2021
Validating the Mandarin version of the Memorial delirium assessment scale in general medical hospital patients Hu, C. H. Chiu, Y. C. Liu, S. I. Ko, K. T. Asia Pac Psychiatry 2021

confusion assessment method
delirium
memorial delirium assessment scale
mini-mental state examination
receiver operating characteristic curve

How do delirium motor subtypes differ in phenomenology and contributory aetiology? a cross-sectional, multisite study of liaison psychiatry and palliative care patients Glynn, K. McKenna, F. Lally, K. O'Donnell, M. Grover, S. Chakrabarti, S. Avasthi, A. Mattoo, S. K. Sharma, A. Gosh, A. Shah, R. Hickey, D. Fitzgerald, J. Davis, B. O'Regan, N. Adamis, D. Williams, O. Awan, F. Dunne, C. Cullen, W. McInerney, S. McFarland, BMJ Open 2021

Adult
Cross-Sectional Studies
Delirium/diagnosis/etiology
Humans
India
Ireland/epidemiology
Palliative Care
Psychiatry
Severity of Illness Index
delirium & cognitive disorders
dementia
geriatric medicine

Frailty, post-operative delirium and functional status at discharge in patients with hip fracture Gandossi, C. M. Zambon, A. Oliveri, G. Codognola, M. Szabo, H. Cazzulani, I. Ferrara, M. C. Mottadelli, C. Galeazzi, M. Amoroso, I. Zarcone, C. Principato, G. Corsi, M. Mazzola, P. Zatti, G. Foti, G. Bellelli, G. Int J Geriatr Psychiatry 2021

delirium
elderly
frailty
functional outcome
hip fracture
orthogeriatric

The Safety and Efficacy Evaluation of Dexmedetomidine for Procedural Sedation and Postoperative Behaviors in Pediatric Populations: A Systematic Review and Meta-analysis Gan, L. Zhao, X. Chen, X. Ann Pharmacother 2021

delirium
dexmedetomidine
meta-analysis
postoperative behavior
sedation

Association between frailty and postoperative delirium: a meta-analysis of cohort study Fu, D. Tan, X. Zhang, M. Chen, L. Yang, J. Aging Clin Exp Res 2021

Cohort studies
Frailty
Meta-analysis
Postoperative delirium

Incidence and factors associated with delirium in children in a single pediatric intensive care unit in Brazil Flores, A. E. R. Oura, K. H. U. Rocha, P. K. Belela-Anacleto, A. S. C. Kusahara, D. M. J Pediatr Nurs 2021

Delirium
Pediatric intensive care units
Pediatric nursing
Risk factors

Long-Term Outcomes in Intensive Care Unit Patients with Delirium: A Population-Based Cohort Study Fiest, K. M. Soo, A. Hee Lee, C. Niven, D. J. Ely, E. W. Doig, C. J. Stelfox, H. T. Am J Respir Crit Care Med 2021

critical care
delirium
mortality

Impact of Religiosity on Delirium Severity Among Critically Ill Shi'a Muslims: A Prospective Multi-Center Observational Study Farzanegan, B. Elkhatib, T. H. M. Elgazzar, A. E. Moghaddam, K. G. Torkaman, M. Zarkesh, M. Goharani, R. Bashar, F. R. Hajiesmaeili, M. Shojaei, S. Madani, S. J. Vahedian-Azimi, A. Hatamian, S. Mosavinasab, S. M. M. Khoshfetrat, M. Khatir, A. K. Miller, A J Relig Health 2021

Critical Illness
Delirium
Female
Humans
Iran
Islam
Prospective Studies
Critical care
Intensive care unit
Religion
Religiosity

Depression as a predictor of postoperative delirium after cardiac surgery: a systematic review and meta-analysis Falk, A. Kåhlin, J. Nymark, C. Hultgren, R. Stenman, M. Interact Cardiovasc Thorac Surg 2021

Cardiac surgery
Depression
Meta-analysis
Postoperative delirium

The delirium screening tool 4AT in routine clinical practice: prediction of mortality, sensitivity and specificity Evensen, S. Hylen Ranhoff, A. Lydersen, S. Saltvedt, I. Eur Geriatr Med 2021

4at
Delirium
Delirium screening
Geriatrics

Delirium and Associated Length of Stay and Costs in Critically Ill Patients Dziegielewski, C. Skead, C. Canturk, T. Webber, C. Fernando, S. M. Thompson, L. H. Foster, M. Ristovic, V. Lawlor, P. G. Chaudhuri, D. Dave, C. Herritt, B. Bush, S. H. Kanji, S. Tanuseputro, P. Thavorn, K. Rosenberg, E. Kyeremanteng, K. Crit Care Res Pract 2021
Opioid Use Increases the Risk of Delirium in Critically Ill Adults Independently of Pain Duprey, M. S. Dijkstra-Kersten, S. M. A. Zaal, I. J. Briesacher, B. A. Saczynski, J. S. Griffith, J. L. Devlin, J. W. Slooter, A. J. C. Am J Respir Crit Care Med 2021

delirium
intensive care
medication
opioid
pain

Association Between Incident Delirium Treatment With Haloperidol and Mortality in Critically Ill Adults uprey, M. S. Devlin, J. W. van der Hoeven, J. G. Pickkers, P. Briesacher, B. A. Saczynski, J. S. Griffith, J. L. van den Boogaard, M. Crit Care Med 2021
Descriptive analysis of the unwarranted continuation of antipsychotics for the management of ICU delirium during transitions of care: A multicenter evaluation across New Jersey Dixit, D. Andrews, L. B. Radparvar, S. Adams, C. Kumar, S. T. Cardinale, M. Am J Health Syst Pharm 2021

ICU delirium
antipsychotics
inappropriate prescribing
intensive care unit
medication safety
transitions of care

Cluster nursing can reduce postoperative delirium and improve the negative emotions and quality of life of elderly ICU patients Di, J. Wang, X. Chen, J. Am J Transl Res 2021

Cluster nursing
delirium
elderly
intensive care unit
quality of life

Cluster nursing can reduce postoperative delirium and improve the negative emotions and quality of life of elderly ICU patients Di, J. Wang, X. Chen, J. Am J Transl Res 2021

Cluster nursing
delirium
elderly
intensive care unit
quality of life

Influence of intraoperative and postoperative factors on the predictive capacity of the delirium risk model for cardiac surgery patients (DELIPRECAS): An observational multicentre study de la Varga-Martínez, O. Gómez-Pesquera, E. Muñoz-Moreno, M. F. Marcos-Vidal, J. M. López-Gómez, A. Rodenas-Gómez, F. Ramasco, F. Álvarez-Refojo, F. Barón, M. S. Tamayo, E. Heredia-Rodríguez, M. Gómez-Sánchez, E. J Clin Anesth 2021

Cardiac Surgical Procedures/adverse effects
Delirium/diagnosis/epidemiology/etiology
Humans
Postoperative Complications/diagnosis/epidemiology/etiology
Risk Factors
Cardiac surgery
Delirium
Prevention

Older trauma patients are at high risk of delirium, especially those with underlying dementia or baseline frailty Ní Chróinín D Francis, N. Wong, P. Kim, Y. D. Nham, S. D'Amours, S. Trauma Surg Acute Care Open 2021

cognition
frailty
geriatrics
patient outcome assessment

The Impact of Monitoring Depth of Anesthesia and Nociception on Postoperative Cognitive Function in Adult Multiple Trauma Patients Cotae, A. M. Ţigliş, M. Cobilinschi, C. Băetu, A. E. Iacob, D. M. Grinţescu, I. M. Medicina (Kaunas) 2021

Adult
Cognition
Delirium
Humans
Middle Aged
Multiple Trauma
Neuropsychological Tests
Nociception
Postoperative Complications
Prospective Studies
Pocd
anesthesia depth
entropy
general emergency surgery

Outcomes of trimodality CROSS regimen in older adults with locally advanced esophageal cancer Cooper, L. Dezube, A. R. De León, L. E. Kucukak, S. Mazzola, E. Dumontier, C. Mamon, H. Enzinger, P. Jaklitsch, M. T. Frain, L. N. Wee, J. O. Eur J Surg Oncol 2021

Cross
Esophageal cancer
Esophagectomy
Neoadjuvant toxicity
Older adults

Nursing intervention to prevent delirium in critically ill adults Contreras, C. C. T. Páez-Esteban, A. N. Rincon-Romero, M. K. Carvajal, R. R. Herrera, M. M. Castillo, Ahdd Rev Esc Enferm USP 2021
Changes in Sedation Practices in Association with Delirium Screening in Infants After Cardiopulmonary Bypass Chomat, M. R. Said, A. S. Mann, J. L. Wallendorf, M. Bickhaus, A. Figueroa, M. Pediatr Cardiol 2021

Cornell Assessment of Pediatric Delirium
Dexmedetomidine
Pediatric cardiac surgery
Pediatric delirium
Sedation
Sedation wean

Risk factors of postoperative delirium after cardiac surgery: a meta-analysis Chen, H. Mo, L. Hu, H. Ou, Y. Luo, J. J Cardiothorac Surg 2021

Age Factors
Cardiac Surgical Procedures/ adverse effects
Carotid Stenosis/epidemiology
Cognitive Dysfunction/epidemiology
Delirium/ etiology
Depression/epidemiology
Diabetes Mellitus/epidemiology
Humans
Intensive Care Units
Length of Stay
Postoperative Complications/etiology
Respiration, Artificial
Risk Factors
Cardiac surgery
Meta-analysis
Postoperative delirium

Diagnosis of overweight or obese malnutrition spells DOOM for hip fracture patients: A prospective audit Bell, J. J. Pulle, R. C. Lee, H. B. Ferrier, R. Crouch, A. Whitehouse, S. L. Clin Nutr 2021

Body mass index
Hip fracture
Malnutrition
Obesity
Overweight

Risk factors for delirium among hospitalized patients in Zambia Mateyo, K. Yan, Y. Liu, D. Zuo, Y. Di Gravio, C. Thome, J. C. Riviello, E. D. Saylor, D. Ely, E. W. Heimburger, D. C. PLoS One 2021
Risk factors associated with treatment of hyperactive postoperative delirium in elderly patients following hip fracture surgery under regional anesthesia: a nationwide population-based study Ahn, E. J. Bang, S. R. Braz J Anesthesiol 2021

Anesthesia
Delirium
Hip fracture

Incidence of delirium in the critical care unit and risk factors in the Central Region, Saudi Arabia Abazid, R. M. Al-Harbi, S. A. Allihimy, A. S. Aldrewesh, D. A. Alkuraydis, S. A. Alhammad, I. M. Elbashir, A. Y. Widyan, A. M. Abohamr, S. I. Saudi Med J 2021

Saudi
critical care
delirium

The risk factors of postoperative delirium in patients with hip fracture: implication for clinical management Xu, W. Ma, H. Li, W. Zhang, C. BMC Musculoskelet Disord 2021

Delirium/diagnosis/epidemiology/etiology
Hip Fractures/epidemiology/surgery
Humans
Incidence
Postoperative Complications/diagnosis/epidemiology/etiology
Risk Factors
Delirium
Hip fracture
Nursing care
Risk
Surgery

Nationwide mortality trends of delirium in Australia and the United States from 2006 to 2016 Wu, H. Mach, J. Le Couteur, D. G. Hilmer, S. N. Australas J Ageing 2021

delirium
geriatrics
mortality
sex differences
trends

The Use of Near-Infrared Spectroscopy and/or Transcranial Doppler as Non-Invasive Markers of Cerebral Perfusion in Adult Sepsis Patients With Delirium: A Systematic Review Wood, M. D. Boyd, J. G. Wood, N. Frank, J. Girard, T. D. Ross-White, A. Chopra, A. Foster, D. Griesdale, D. E. G. J Intensive Care Med 2021

cerebral autoregulation
delirium
near-infrared spectroscopy
pulsatility index
sepsis
transcranial Doppler

Midazolam Premedication Immediately Before Surgery Is Not Associated With Early Postoperative Delirium Wang, M. L. Min, J. Sands, L. P. Leung, J. M. Anesth Analg 2021
The Effect of a Quality Improvement Intervention on Sleep and Delirium in Critically Ill Patients in a Surgical ICU Tonna, J. E. Dalton, A. Presson, A. P. Zhang, C. Colantuoni, E. Lander, K. Howard, S. Beynon, J. Kamdar, B. B. Chest 2021

critical care
delirium
sleep
sleep hygiene
wakefulness

Association between components of the delirium syndrome and outcomes in hospitalised adults: a systematic review and meta-analysis Tieges, Z. Quinn, T. MacKenzie, L. Davis, D. Muniz-Terrera, G. MacLullich, A. M. J. Shenkin, S. D. BMC Geriatr 2021

Cognition
Cognitive Dysfunction
Delirium/diagnosis
Humans
Altered mental status
Arousal
Attention
Delirium
Mortality
Systematic review

The Prognostic Performance of Frailty for Delirium and Functional Decline in Vascular Surgery Patients Thillainadesan, J. Mudge, A. M. Aitken, S. J. Hilmer, S. N. Cullen, J. S. Yumol, M. F. Close, J. C. T. Norris, C. M. Kerdic, R. Naganathan, V. J Am Geriatr Soc 2021

delirium
frailty
function
geriatric surgery

Efficacy of quetiapine for delirium prevention in hospitalized older medical patients: a randomized double-blind controlled trial Thanapluetiwong, S. Ruangritchankul, S. Sriwannopas, O. Chansirikarnjana, S. Ittasakul, P. Ngamkala, T. Sukumalin, L. Charernwat, P. Saranburut, K. Assavapokee, T. BMC Geriatr 2021

Aged
Antipsychotic Agents/adverse effects
Delirium/diagnosis/drug therapy/prevention & control
Double-Blind Method
Haloperidol/therapeutic use
Humans
Quetiapine Fumarate/adverse effects
Thailand
Delirium
Hospitalized
Older
Prevention
Quetiapine

Effects of Slowness, Frailty, Insufficient Intake, and Delirium in Patients Following Cardiac Surgery: A Cohort Study Teng, C. H. Hsu, R. B. Chi, N. H. Wang, S. S. Chen, Y. S. Chen, S. Y. Chen, C. C. J Cardiovasc Nurs 2021
Factors associated with the severity of delirium Tachibana, M. Inada, T. Ichida, M. Kojima, S. Shioya, M. Wakayama, K. Ozaki, N. Hum Psychopharmacol 2021

Drs-r98
benzodiazepine
delirium
severity
β-blocker

Screening for delirium in the intensive care unit using eDIS-ICU - A purpose-designed app: A pilot study Sutt, A. L. Flaws, D. Gunn, H. Eeles, E. Lye, I. Irvine, L. Patterson, S. Bagshaw, T. O'Luanaigh, C. Tronstad, O. Fraser, J. Aust Crit Care 2021

Delirium
Icu
Screening tools
Technology

Association Among Preoperative Cognitive Performance, Regional Cerebral Oxygen Saturation, and Postoperative Delirium in Older Portuguese Patients Susano, M. J. Dias, M. Seixas, F. S. Vide, S. Grasfield, R. Abelha, F. J. Crosby, G. Culley, D. J. Amorim, P. Anesth Analg 2021

Age Factors
Aged
Aged, 80 and over
Blood Gas Monitoring, Transcutaneous
Cerebrovascular Circulation
Cognition
Cognitive Dysfunction/ complications/diagnosis/psychology
Delirium/diagnosis/ etiology/psychology
Elective Surgical Procedures/ adverse effects
Female
Humans
Male
Neuropsychological Tests
Oxygen/ blood
Portugal
Postoperative Complications/diagnosis/ etiology/psychology
Prospective Studies
Risk Assessment
Risk Factors
Spectroscopy, Near-Infrared
Treatment Outcome

Sleep and circadian rhythm disturbances in intensive care unit (ICU)-acquired delirium: a case-control study Sun, T. Sun, Y. Huang, X. Liu, J. Yang, J. Zhang, K. Kong, G. Han, F. Hao, D. Wang, X. J Int Med Res 2021

Adolescent
Adult
Aged
Case-Control Studies
Circadian Rhythm
Delirium/diagnosis
Humans
Intensive Care Units
Middle Aged
Sleep
Young Adult
Delirium
cortisol
critical care
melatonin
polysomnography
sleep

Terminal Delirium in Hospice: The Experiences and Perspectives of Caregivers Providing Care to Terminally Ill Patients in Home Settings Soroka, J. T. Fling, K. J. Heibel, J. M. Kutcher, G. R. Ward, S. J. Am J Hosp Palliat Care 2021

caregivers
delirium experiences
end-of-life care
hospice home care
interventions
terminal delirium

Estimates of Geriatric Delirium Frequency in Noncardiac Surgeries and Its Evaluation Across the Years: A Systematic Review and Meta-analysis Silva, A. R. Regueira, P. Albuquerque, E. Baldeiras, I. Cardoso, A. L. Santana, I. Cerejeira, J. J Am Med Dir Assoc 2021

Delirium
anesthesia
frequency
incidence
noncardiac surgery
old age

The Effects of Bispectral Index-Guided Anesthesia on Postoperative Delirium in Elderly Patients: A Systematic Review and Meta-Analysis Shan, W. Chen, B. Huang, L. Zhou, Y. World Neurosurg 2021

Bispectral index
Elderly patients
Major surgery
Postoperative delirium

Validation of the Delirium Diagnostic Tool-Provisional (DDT-Pro) in a skilled nursing facility and comparison to the 4 'A's test (4AT) Sepúlveda, E. Bermúdez, E. González, D. Cotino, P. Viñuelas, E. Palma, J. Ciutat, M. Grau, I. Vilella, E. Trzepacz, P. T. Franco, J. G. Gen Hosp Psychiatry 2021

Delirium diagnosis
Diagnostic tests comparison.
Geriatric assessment.
Psychiatric status rating scales.
Skilled nursing.

Evaluation of Delirium in Critically Ill Patients Prescribed Melatonin or Ramelteon Romero, N. Dube, K. M. Lupi, K. E. DeGrado, J. R. Ann Pharmacother 2021

agitation
delirium
intensive care unit
melatonin
ramelteon
sedation

Delirium and delirium severity predict the trajectory of the Hierarchical Assessment of Balance and Mobility (HABAM) in hospitalised older people: findings from the DECIDE Study Richardson, S. Murray, J. Davis, D. Stephan, B. C. M. Robinson, L. Brayne, C. Barnes, L. Parker, S. Sayer, A. Dodds, R. Allan, L. J Gerontol A Biol Sci Med Sci 2021

Epidemiology
Hospital related
Physical function

Common biomarkers of physiologic stress and associations with delirium in patients with intracerebral hemorrhage Reznik, M. E. Kalagara, R. Moody, S. Drake, J. Margolis, S. A. Cizginer, S. Mahta, A. Rao, S. S. Stretz, C. Wendell, L. C. Thompson, B. B. Asaad, W. F. Furie, K. L. Jones, R. N. Daiello, L. A. J Crit Care 2021

Biomarkers
Delirium
Intracerebral hemorrhage

Effects of Preoperative Anxiety on Postoperative Delirium in Elderly Patients Undergoing Elective Orthopedic Surgery: A Prospective Observational Cohort Study Ren, A. Zhang, N. Zhu, H. Zhou, K. Cao, Y. Liu, J. Clin Interv Aging 2021

Aged
Aged, 80 and over
Anxiety/ epidemiology
Cohort Studies
Delirium/ epidemiology
Elective Surgical Procedures/ adverse effects
Female
Humans
Logistic Models
Male
Mental Status and Dementia Tests
Odds Ratio
Orthopedic Procedures/ adverse effects
Postoperative Complications/ epidemiology
Prospective Studies
Risk Factors
anxiety
delirium
orthopedic

Hyperactive delirium in patients after non-traumatic subarachnoid hemorrhage Reimann, F. Rinner, T. Lindner, A. Kofler, M. Ianosi, B. A. Schiefecker, A. J. Beer, R. Schmutzhard, E. Pfausler, B. Helbok, R. Rass, V. J Crit Care 2021

Critical care
Delirium
Intensive care delirium screening checklist
Subarachnoid hemorrhage

Prescribing Practices of Valproic Acid for Agitation and Delirium in the Intensive Care Unit Quinn, N. J. Hohlfelder, B. Wanek, M. R. Duggal, A. Torbic, H. Ann Pharmacother 2021

Aged
Anticonvulsants/pharmacology/ therapeutic use
Antipsychotic Agents/ therapeutic use
Cohort Studies
Female
Humans
Incidence
Intensive Care Units/ standards
Male
Middle Aged
Psychomotor Agitation/ drug therapy
Retrospective Studies
Valproic Acid/pharmacology/ therapeutic use
agitation
critical illness
delirium
sedation
valproic acid

Delirium and Mortality in Coronavirus Disease 2019 (COVID-19) - A Systematic Review and Meta-analysis Pranata, R. Huang, I. Lim, M. A. Yonas, E. Vania, R. Kuswardhani, R. A. T. Arch Gerontol Geriatr 2021

Aged

Covid-19
Delirium/diagnosis/epidemiology
Humans
Hypertension/epidemiology
Male
Pandemics
SARS-CoV-2
Confusion
Delirium
Geriatric
Severe

Dexmedetomidine vs. total intravenous anaesthesia in paediatric emergence delirium: A network meta-analysis Petre, M. A. Levin, D. N. Englesakis, M. Maynes, J. T. Pechlivanoglou, P. Aoyama, K. Eur J Anaesthesiol 2021
Delirium prevalence in a Colombian hospital, association with geriatric syndromes and complications during hospitalization Peralta-Cuervo, A. F. Garcia-Cifuentes, E. Castellanos-Perilla, N. Chavarro-Carvajal, D. A. Venegas-Sanabria, L. C. Cano-Gutiérrez, C. A. Rev Esp Geriatr Gerontol 2021

Aged
Delirio
Delirium
Envejecido
Factores de riesgo
Funcionalidad
Functionality
Mortalidad
Mortality
Risk factors

Anticholinergic load and delirium in end-of-life patients Pasina, L. Rizzi, B. Nobili, A. Recchia, A. Eur J Clin Pharmacol 2021

Anticholinergic drugs
Delirium
Elderly
End-of-life

Patients, family members and providers perceive family-administered delirium detection tools in the adult ICU as feasible and of value to patient care and family member coping: a qualitative focus group study Parsons Leigh, J. Krewulak, K. D. Zepeda, N. Farrier, C. E. Spence, K. L. Davidson, J. E. Stelfox, H. T. Fiest, K. M. Can J Anaesth 2021

Adaptation, Psychological
Adult
Alberta
Delirium/diagnosis
Family
Focus Groups
Humans
Intensive Care Units
Icu
critical care
delirium

Serum melatonin concentration in critically ill patients randomized to sedation or non-sedation Oxlund, J. Knudsen, T. Strøm, T. Lauridsen, J. T. Jennum, P. J. Toft, P. Ann Intensive Care 2021

Circadian
Delirium
Melatonin
Non-sedation
Rhythm
Sedation

Depression predicts cognitive and functional decline one month after coronary artery bypass graft surgery (Neuropsychiatric Outcomes After Heart Surgery study) Oldham, M. A. Lin, I. H. Hawkins, K. A. Li, F. Y. Yuh, D. D. Lee, H. B. Int J Geriatr Psychiatry 2021

Aged
Cardiac Surgical Procedures
Cognition
Coronary Artery Bypass
Depression
Female
Humans
Neuropsychological Tests
Prospective Studies
CABGsurgery
cognitive decline
functional status
neuropsychological testing

Effect of deep neuromuscular blockade on serum cytokines and postoperative delirium in elderly patients undergoing total hip replacement: A prospective single-blind randomised controlled trial Oh, C. S. Lim, H. Y. Jeon, H. J. Kim, T. H. Park, H. J. Piao, L. Kim, S. H. Eur J Anaesthesiol 2021

Aged
Arthroplasty, Replacement, Hip/adverse effects
Cytokines
Delirium/diagnosis/epidemiology/etiology
Double-Blind Method
Humans
Neuromuscular Blockade
Prospective Studies
Single-Blind Method

Cerebral autoregulation in the operating room and intensive care unit after cardiac surgery Nakano, M. Nomura, Y. Whitman, G. Sussman, M. Schena, S. Kilic, A. Choi, C. W. Akiyoshi, K. Neufeld, K. J. Lawton, J. Colantuoni, E. Yamaguchi, A. Wen, M. Smielewski, P. Brady, K. Bush, B. Hogue, C. W. Brown, C. H. th Br J Anaesth 2021

Aged
Arterial Pressure/ physiology
Cardiac Surgical Procedures/ methods
Cerebrovascular Circulation/ physiology
Delirium/ physiopathology
Female
Homeostasis/physiology
Humans
Intensive Care Units
Male
Middle Aged
Monitoring, Intraoperative/methods
Operating Rooms
Oximetry
cardiac surgery
cerebral autoregulation
delirium
geriatrics
intensive care unit

Propofol plus low-dose dexmedetomidine infusion and postoperative delirium in older patients undergoing cardiac surgery Momeni, M. Khalifa, C. Lemaire, G. Watremez, C. Tircoveanu, R. Van Dyck, M. Kahn, D. Rosal Martins, M. Mastrobuoni, S. De Kerchove, L. Zango, S. H. Jacquet, L. M. Br J Anaesth 2021

Aged
Cardiac Surgical Procedures
Delirium/ prevention & control
Dexmedetomidine/ administration & dosage/therapeutic use
Dose-Response Relationship, Drug
Double-Blind Method
Drug Therapy, Combination
Female
Humans
Hypnotics and Sedatives/administration & dosage/ therapeutic use
Infusions, Intravenous
Male
Postoperative Complications/ prevention & control
Propofol/ administration & dosage/therapeutic use
Treatment Outcome
Confusion Assessment Method
cardiac surgery
dexmedetomidine
older patients
postoperative delirium

Delirium REduction after administration of melatonin in acute ischemic stroke (DREAMS): A propensity score-matched analysis Mengel, A. Zurloh, J. Boßelmann, C. Brendel, B. Stadler, V. Sartor-Pfeiffer, J. Meisel, A. Fleischmann, R. Ziemann, U. Poli, S. Stefanou, M. I. Eur J Neurol 2021

delirium
delirium prevention
ischemic stroke
melatonin
poststroke delirium

Incidence, Risk Factors and Impact on Long-Term Outcome of Postoperative Delirium After Transcatheter Aortic Valve Replacement Mauri, V. Reuter, K. Körber, M. I. Wienemann, H. Lee, S. Eghbalzadeh, K. Kuhn, E. Baldus, S. Kelm, M. Nickenig, G. Veulemans, V. Jansen, F. Adam, M. Rudolph, T. K. Front Cardiovasc Med 2021

Tavr
delirium
frailty
survival
transcatheter aortic valve implantation

Predisposing and Precipitating Factors for Delirium in the Very Old (≥80 Years): A Prospective Cohort Study of 3,076 Patients Marquetand, J. Bode, L. Fuchs, S. Ernst, J. von Känel, R. Boettger, S. Gerontology 2021

80 years
Delirium
Disorders
Risk factors
Very old

Delirium and Functional Recovery in Patients Discharged to Skilled Nursing Facilities After Hospitalization for Heart Failure Madrigal, C. Kim, J. Jiang, L. Lafo, J. Bozzay, M. Primack, J. Correia, S. Erqou, S. Wu, W. C. Rudolph, J. L. JAMA Netw Open 2021

Activities of Daily Living
Aged
Aged, 80 and over
Delirium
Dementia
Female
Heart Failure/psychology/ rehabilitation/therapy
Hospitalization
Humans
Male
Patient Discharge
Patient Readmission
Recovery of Function
Retrospective Studies
Skilled Nursing Facilities
United States

Prevalence of high-risk medications in patients enrolled in the Hospital Elder Life Program Macias Tejada, J. A. Klumph, M. Heslin, K. Khan, A. Malone, M. L. J Am Geriatr Soc 2021

antipsychotics
benzodiazepines
delirium
high-risk medications
hospital elder life program

Acupuncture Treatment of Delirium in Older Adults Hospitalized in Internal Medicine Departments: An Open-Label Pragmatic Randomized-Controlled Trial Levy, I. Gavrieli, S. Hefer, T. Attias, S. Schiff, A. Oliven, R. Wisberg-Levi, S. Hanchinsky, R. Schiff, E. J Geriatr Psychiatry Neurol 2021

acupuncture
delirium
hospitalization
internal medicine
older adults
traditional Chinese medicine

Impact of an orthogeriatric collaborative care model for older adults with hip fracture in a community hospital setting Lee, J. C. Koo, K. Wong, E. K. C. Naqvi, R. Wong, C. L. Can J Surg 2021
Cardiac Delirium Index for Predicting the Occurrence of Postoperative Delirium in Adult Patients After Coronary Artery Bypass Grafting Lechowicz, K. Szylińska, A. Listewnik, M. Drożdżal, S. Tomska, N. Rotter, I. Kotfis, K. Clin Interv Aging 2021

Aged
Biomarkers/blood
C-Reactive Protein/analysis
Coronary Artery Bypass/ adverse effects
Delirium/ blood/ etiology
Female
Humans
Male
Middle Aged
Postoperative Complications/epidemiology
Retrospective Studies
Risk Assessment
Risk Factors
Cabg
Cam-icu
Pod
cardiac surgery
coronary artery bypass grafting
delirium

Delirium documentation in hospitalized pediatric patients with cancer Lastrapes, K. Dang, M. Cassel, J. B. Orr, T. Proffitt, T. Del Fabbro, E. Palliat Support Care 2021

Delirium
Documentation and ICD coding for delirium
Pediatric oncology

Efficacy of two integrated geriatric care pathways for the treatment of hip fractures: a cross-cultural comparison Kusen, J. Q. van der Vet, P. C. R. Wijdicks, F. J. G. Verleisdonk, Ejjm Link, B. C. Houwert, R. M. Knobe, M. van der Velde, D. Babst, R. Beeres, F. J. P. Eur J Trauma Emerg Surg 2021

Clinical pathway
Cross-cultural comparison
Geriatrician
Hip fracture
Trauma surgeon

Depressed mood, associated factors, and understanding of delirium among caregivers of patients with delirium Kim, S. Y. Jhon, M. Kang, H. J. Lee, J. Y. Kim, S. W. Kim, J. M. Shin, I. S. Int J Psychiatry Med 2021

caregiver
delirium
depression
education
information
misinterpretation

Scheduled Prophylactic 6-Hourly IV AcetaminopheN to Prevent Postoperative Delirium in Older CaRdiac SurgicAl Patients (PANDORA): protocol for a multicentre randomised controlled trial Khera, T. Mathur, P. A. Banner-Goodspeed, V. M. Narayanan, S. McGourty, M. Kelly, L. Palihnich, K. Novack, L. Davis, R. Talmor, D. Marcantonio, E. R. Subramaniam, B. BMJ Open 2021

Acetaminophen
Aged
Boston
Cardiac Surgical Procedures/adverse effects
Cerebrovascular Circulation
Delirium/prevention & control
Double-Blind Method
Humans
Multicenter Studies as Topic
Oximetry
Randomized Controlled Trials as Topic
adult intensive & critical care
anaesthesia in cardiology
cardiac surgery
delirium & cognitive disorders

Serum Biomarkers in Postoperative Delirium after Esophagectomy Khan, S. H. Lindroth, H. Jawed, Y. Wang, S. Nasser, J. Seyffert, S. Naqvi, K. Perkins, A. J. Gao, S. Kesler, K. Khan, B. Ann Thorac Surg 2021

biomarkers
c-reactive protein
delirium
esophagectomy
postoperative delirium

Drug-related problems of antipsychotics in treating delirium among elderly patients: A real-world observational study Jenraumjit, R. Somboon, J. Chainan, S. Chuenchom, P. Wongpakaran, N. Wongpakaran, T. J Clin Pharm Ther 2021

antipsychotics
delirium
drug-related problems
elderly

Effect of Melatonin on Delirium After on-Pump Coronary Artery Bypass Graft Surgery: A Randomized Clinical Trial Javaherforoosh Zadeh, F. Janatmakan, F. Shafaeebejestan, E. Jorairahmadi, S Iran J Med Sci 2021

Delirium
Melatonin
Thoracic surgery

A polysomnography study examining the association between sleep and postoperative delirium in older hospitalized cardiac surgical patients Ibala, R. Mekonnen, J. Gitlin, J. Hahm, E. Y. Ethridge, B. R. Colon, K. M. Marota, S. Ortega, C. Pedemonte, J. C. Cobanaj, M. Chamadia, S. Qu, J. Gao, L. Barbieri, R. Akeju, O. J Sleep Res 2021

cardiac surgery
delirium
hospitalization
older
polysomnography
sleep

Delirium in older patients undergoing aortic valve replacement: incidence, predictors, and cognitive prognosis Humbert, M. Büla, C. J. Muller, O. Krief, H. Monney, P. BMC Geriatr 2021

Activities of Daily Living
Aged
Aged, 80 and over
Aortic Valve/surgery
Cognition
Delirium/diagnosis/epidemiology/etiology
Heart Valve Prosthesis Implantation/adverse effects
Humans
Incidence
Prognosis
Prospective Studies
Risk Assessment
Risk Factors
Treatment Outcome
Aortic stenosis
Delirium
Society of thoracic surgeons risk score
Surgical aortic valve replacement
Transcatheter aortic valve replacement

A clinical risk analysis of early post-operative delirium after laparoscopic colorectal cancer surgery in elderly patients: a retrospective study Hiraki, M. Tanaka, T. Ishii, H. Sadashima, E. Miura, D. Sunami, T. Hanafusa, K. Sato, H. Kitahara, K. Int J Colorectal Dis 2021

Aged
Aged, 80 and over
Colorectal Neoplasms/surgery
Delirium
Humans
Laparoscopy/adverse effects
Postoperative Complications/etiology
Retrospective Studies
Risk Assessment
Risk Factors
Colorectal cancer
Elderly patient
Laparoscopic surgery
Post-operative delirium

Nurses' experiences of delirium and how to identify delirium-A qualitative study Helgesen, A. K. Adan, Y. H. Dybvik Bjørglund, C. Weberg-Haugen, C. Johannessen, M. Åsmul Kristiansen, K. Vasskog Risan, E. Relusco, M. L. Skaarer-Heen, H. M. Sørensen, T. S. Vedå, L. Abrahamsen Grøndahl, V. Nurs Open 2021

Delirium/diagnosis
Female
Focus Groups
Humans
Nurses
Nursing Care
Qualitative Research
community care
delirium
identification
knowledge
qualitative

Preoperative Comparison of Three Anticholinergic Drug Scales in Older Adult Patients and Development of Postoperative Delirium: A Prospective Observational Study Heinrich, M. Müller, A. Cvijan, A. Mörgeli, R. Kruppa, J. Winterer, G. Slooter, A. J. C. Spies, C. D. Drugs Aging 2021
Characterization of Nocturnal Neuroactive Medication Use and Related Sleep Documentation in Critically Ill Adults Hamidi, A. Roberts, R. J. Weinhouse, G. L. Szumita, P. M. Degrado, J. R. Dube, K. M. Kovacevic, M. P. Choi, M. Sevinsky, R. Duprey, M. S. Devlin, J. W. Crit Care Explor 2021

antipsychotics
delirium
intensive care
melatonin
ramelteon
sleep

Optimal interval and duration of CAM-ICU assessments for delirium detection after cardiac surgery Hamadnalla, H. Sessler, D. I. Troianos, C. A. Fang, J. Rivas, E. Ma, C. Mascha, E. J. Turan, A. J Clin Anesth 2021

Anesthesia
Cam-icu
Cognitive impairment
Delirium
Surgery

Is there evidence for using anticonvulsants in the prevention and/or treatment of delirium among older adults? Gupta, A. Joshi, P. Bhattacharya, G. Lehman, M. Funaro, M. Tampi, D. J. Tampi, R. R. Int Psychogeriatr 2021

anticonvulsants
delirium
gabapentin
older adults
pregabalin
prevention
treatment

Is there evidence for using anticonvulsants in the prevention and/or treatment of delirium among older adults? Gupta, A. Joshi, P. Bhattacharya, G. Lehman, M. Funaro, M. Tampi, D. J. Tampi, R. R. Int Psychogeriatr 2021

anticonvulsants
delirium
gabapentin
older adults
pregabalin
prevention
treatment

Association of CSF Alzheimer's disease biomarkers with postoperative delirium in older adults Fong, T. G. Vasunilashorn, S. M. Gou, Y. Libermann, T. A. Dillon, S. Schmitt, E. Arnold, S. E. Kivisäkk, P. Carlyle, B. Oh, E. S. Vlassakov, K. Kunze, L. Hshieh, T. Jones, R. N. Marcantonio, E. R. Inouye, S. K. Alzheimers Dement (N Y) 2021

AD biomarkers
delirium

Impact of Delirium and Its Motor Subtypes on Stroke Outcomes Fialho Silva, I. T. Assis Lopes, P. Timotio Almeida, T. Ramos, S. C. Caliman Fontes, A. T. Guimarães Silva, D. Martins Soares, C. Oliveira Carneiro, L. Souza, I. F. B. Ferreira Abreu, F. Nascimento Silva, G. Mascarenhas de Souza, L. Brito Pinheiro, T. de Stroke 2021

cognition
death
delirium
intensive care unit
prognosis
stroke