What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Preventing Postoperative Delirium After Major Noncardiac Thoracic Surgery-A Randomized Clinical Trial.
- Authors
- Khan, B. A. Perkins, A. J. Campbell, N. L. Gao, S. Khan, S. H. Wang, S. Fuchita, M. Weber, D. J. Zarzaur, B. L. Boustani, M. A. Kesler, K.
- Year
- 2018
- Journal
- J Am Geriatr Soc
- Abstract
OBJECTIVES: To assess the efficacy of haloperidol in reducing postoperative delirium in individuals undergoing thoracic surgery. DESIGN: Randomized double-blind placebo-controlled trial. SETTING: Surgical intensive care unit (ICU) of tertiary care center. PARTICIPANTS: Individuals undergoing thoracic surgery (N=135). INTERVENTION: Low-dose intravenous haloperidol (0.5 mg three times daily for a total of 11 doses) administered postoperatively. MEASUREMENTS: The primary outcome was delirium incidence during hospitalization. Secondary outcomes were time to delirium, delirium duration, delirium severity, and ICU and hospital length of stay. Delirium was assessed using the Confusion Assessment Method for the ICU and delirium severity using the Delirium Rating Scale-Revised. RESULTS: Sixty-eight participants were randomized to receive haloperidol and 67 placebo. No significant differences were observed between those receiving haloperidol and those receiving placebo in incident delirium (n=15 (22.1%) vs n=19 (28.4%); p = .43), time to delirium (p = .43), delirium duration (median 1 day, interquartile range (IQR) 1-2 days vs median 1 day, IQR 1-2 days; p = .71), delirium severity, ICU length of stay (median 2.2 days, IQR 1-3.3 days vs median 2.3 days, IQR 1-4 days; p = .29), or hospital length of stay (median 10 days, IQR 8-11.5 days vs median 10 days, IQR 8-12 days; p = .41). In the esophagectomy subgroup (n = 84), the haloperidol group was less likely to experience incident delirium (n=10 (23.8%) vs n=17 (40.5%); p = .16). There were no differences in time to delirium (p = .14), delirium duration (median 1 day, IQR 1-2 days vs median 1 day, IQR 1-2 days; p = .71), delirium severity, or hospital length of stay (median 11 days, IQR 10-12 days vs median days 11, IQR 10-15 days; p = .26). ICU length of stay was significantly shorter in the haloperidol group (median 2.8 days, IQR 1.1-3.8 days vs median 3.1 days, IQR 2.1-5.1 days; p = .03). Safety events were comparable between the groups. CONCLUSION: Low-dose postoperative haloperidol did not reduce delirium in individuals undergoing thoracic surgery but may be efficacious in those undergoing esophagectomy. J Am Geriatr Soc 66:2289-2297, 2018.
- PMID
- Keywords
Icu
cognition
delirium
esophagectomy
haloperidol
- Page(s)
- 2289-97
- Volume
- 66
- Issue
- 12
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| Visual Analytics in Delirium Management | Hackl, W. O. Netzer, M. Nantschev, R. Schaller, M. Ammenwerth, E. | Stud Health Technol Inform | 2021 |
Aged |
| Characterizing Sleep Disruption and Delirium in Children After Cardiac Surgery: A Feasibility Study | Gregory, J. L. Brown, A. T. Kudchadkar, S. R. | Pediatr Crit Care Med | 2021 | |
| One-Year Medicare Costs Associated With Delirium in Older Patients Undergoing Major Elective Surgery | Gou, R. Y. Hshieh, T. T. Marcantonio, E. R. Cooper, Z. Jones, R. N. Travison, T. G. Fong, T. G. Abdeen, A. Lange, J. Earp, B. Schmitt, E. M. Leslie, D. L. Inouye, S. K. | JAMA Surg | 2021 | |
| Implementing Delirium Screening in an Intermediate Care Unit | Gaa, C. A. Akintade, B. F. | J Dr Nurs Pract | 2021 |
confusion assessment method |
| Malocclusion of Molar Teeth Is Associated with Activities of Daily Living Loss and Delirium in Elderly Critically Ill Older Patients | Fujinami, Y. Hifumi, T. Ono, Y. Saito, M. Okazaki, T. Shinohara, N. Akiyama, K. Kunikata, M. Inoue, S. Kotani, J. Kuroda, Y. | J Clin Med | 2021 |
ICU prognosis |
| Electroencephalography of mechanically ventilated patients at high risk of delirium | Eskioglou, E. Iaquaniello, C. Alvarez, V. Rüegg, S. Schindler, K. Rossetti, A. O. Oddo, M. | Acta Neurol Scand | 2021 |
Eeg |
| Risk Factors and Antipsychotic Usage Patterns Associated With Terminal Delirium in a Veteran Long-Term Care Hospice Population | Ellsworth, E. M. Bacigalupo, K. J. Palla, K. R. Limaye, S. S. Walkosz, M. J. Szczecinski, S. T. Suda, K. J. | Fed Pract | 2021 | |
| Does cognitive decline/dementia increase Delirium risk after stroke? | Ding, G. Hua, S. Chen, J. Yang, S. Xie, R. | Psychogeriatrics | 2021 |
Cognitive Dysfunction |
| Heterogeneity in design and analysis of ICU delirium randomized trials: a systematic review | Colantuoni, E. Koneru, M. Akhlaghi, N. Li, X. Hashem, M. D. Dinglas, V. D. Neufeld, K. J. Harhay, M. O. Needham, D. M. | Trials | 2021 |
Adult |
| The frequency and quality of delirium documentation in discharge summaries | Chuen, V. L. Chan, A. C. H. Ma, J. Alibhai, S. M. H. Chau, V. | BMC Geriatr | 2021 |
Delirium/diagnosis/epidemiology |
| Using data linkage for national surveillance of clinical quality indicators for dementia care among Australian aged care users | Cations, M. Lang, C. Ward, S. A. Caughey, G. E. Crotty, M. Whitehead, C. Ahern, S. Maddison, J. Inacio, M. C. | Sci Rep | 2021 | |
| Geriatric fracture centre vs usual care after proximal femur fracture in older patients: what are the benefits? Results of a large international prospective multicentre study | Blauth, M. Joeris, A. Rometsch, E. Espinoza-Rebmann, K. Wattanapanom, P. Jarayabhand, R. Poeze, M. Wong, M. K. Kwek, E. B. K. Hegeman, J. H. Perez-Uribarri, C. Guerado, E. Revak, T. J. Zohner, S. Joseph, D. Gosch, M. | BMJ Open | 2021 |
Aged |
| Effects of dexmedetomidine on neurocognitive disturbance after elective non-cardiac surgery in senile patients: a systematic review and meta-analysis | Bi, X. Wei, J. Zhang, X. | J Int Med Res | 2021 |
China |
| Non-pharmacological interventions for preventing delirium in hospitalised non-ICU patients (Review) | Burton JK, Craig LE, Yong SQ, Siddiqi N, Teale EA, Woodhouse R, Barugh AJ, Shepherd AM, Brunton A, Freeman SC, Sutton AJ, Quinn TJ | Cochrane Database of Systematic Reviews | 2021 | |
| Incidence and risk factors for postoperative delirium after liver transplantation: a systematic review and meta-analysis | Zhou, S. Deng, F. Zhang, J. Chen, G. | Eur Rev Med Pharmacol Sci | 2021 | |
| The perioperative application of continuous cerebral autoregulation monitoring for cerebral protection in elderly patients | Zhang, Y. Tan, J. Li, P. Zhang, X. Yang, Y. Liu, Y. Fu, Q. Cao, J. Mi, W. Zhang, H. Li, H. | Ann Palliat Med | 2021 |
Aged |
| Prospective Randomized Controlled Pilot Study of High-Intensity Lightbox Phototherapy to Prevent ICU-Acquired Delirium Incidence | Zhang, K. S. Pelleg, T. Hussain, S. Kollipara, V. Loschner, A. Foroozesh, M. B. Rubio, E. Biscardi, F. Ie, S. R. | Cureus | 2021 |
bright light therapy |
| Neurocognitive disorders in the elderly: altered functional resting-state hyperconnectivities in postoperative delirium patients | Winterer, J. M. Ofosu, K. Borchers, F. Hadzidiakos, D. Lammers-Lietz, F. Spies, C. Winterer, G. Zacharias, N. | Transl Psychiatry | 2021 |
Aged |
| Relationships between preoperative cortical thickness, postoperative electroencephalogram slowing, and postoperative delirium | White, M. F. Tanabe, S. Casey, C. Parker, M. Bo, A. Kunkel, D. Nair, V. Pearce, R. A. Lennertz, R. Prabhakaran, V. Lindroth, H. Sanders, R. D. | Br J Anaesth | 2021 |
cortical slowing |
| COVID-19 in adults with dementia: clinical features and risk factors of mortality-a clinical cohort study on 125 patients | Vrillon, A. Mhanna, E. Aveneau, C. Lebozec, M. Grosset, L. Nankam, D. Albuquerque, F. Razou Feroldi, R. Maakaroun, B. Pissareva, I. Cherni Gherissi, D. Azuar, J. François, V. Hourrègue, C. Dumurgier, J. Volpe-Gillot, L. Paquet, C. | Alzheimers Res Ther | 2021 |
Aged, 80 and over |
| Risk Factors for Delirium after Vascular Surgery: A Systematic Review and Meta-Analysis | Visser, L. Prent, A. Banning, L. B. D. van Leeuwen, B. L. Zeebregts, C. J. Pol, R. A. | Ann Vasc Surg | 2021 | |
| Etiologies of Delirium in Consecutive COVID-19 Inpatients and the Relationship Between Severity of Delirium and COVID-19 in a Prospective Study With Follow-Up | Velásquez-Tirado, J. D. Trzepacz, P. T. Franco, J. G. | J Neuropsychiatry Clin Neurosci | 2021 |
Covid-19 |
| Increased Emergency Department Hallway Length of Stay is Associated with Development of Delirium | van Loveren, K. Singla, A. Sinvani, L. Calandrella, C. Perera, T. Brave, M. Becker, L. Li, T. | West J Emerg Med | 2021 |
Adolescent |
| Delirium in Children Undergoing Hematopoietic Cell Transplantation: A Multi-Institutional Point Prevalence Study | Traube, C. Gerber, L. M. Mauer, E. A. Small, K. Broglie, L. Chopra, Y. R. Duncan, C. N. Ebens, C. L. Fitzgerald, J. C. Freedman, J. L. Hudspeth, M. P. Hurley, C. Mahadeo, K. M. McArthur, J. Shapiro, M. C. Sharron, M. P. Wall, D. A. Zinter, M. S. Greenwald | Front Oncol | 2021 |
cancer |
| Agreement Between the Mini-Cog in the Preoperative Clinic and on the Day of Surgery and Association With Postanesthesia Care Unit Delirium: A Cohort Study of Cognitive Screening in Older Adults | Tiwary, N. Treggiari, M. M. Yanez, N. D. Kirsch, J. R. Tekkali, P. Taylor, C. C. Schenning, K. J. | Anesth Analg | 2021 |
Aged |
| A qualitative analysis of clinicians' communication strategies with family members of patients experiencing hospital-acquired delirium | Taylor, G. B. Radhakrishnan, N. Fisher, C. L. Price, C. Tighe, P. Le, T. Bylund, C. L. | Geriatr Nurs | 2021 | |
| A scalable approach for developing clinical risk prediction applications in different hospitals | Sun, H. Depraetere, K. Meesseman, L. De Roo, J. Vanbiervliet, M. De Baerdemaeker, J. Muys, H. von Dossow, V. Hulde, N. Szymanowsky, R. | J Biomed Inform | 2021 |
Acute kidney injury |
| The Relative Impact of Specific Postoperative Complications on Older Patients Undergoing Hip Fracture Repair | Stahl, C. C. Funk, L. M. Schumacher, J. R. Zarzaur, B. L. Scarborough, J. E. | Jt Comm J Qual Patient Saf | 2021 | |
| Brain MRI after critical care admission: A longitudinal imaging study | Sprung, J. Warner, D. O. Knopman, D. S. Petersen, R. C. Mielke, M. M. Jack, C. R., Jr. Martin, D. P. Hanson, A. C. Schroeder, D. R. Przybelski, S. A. Schulte, P. J. Laporta, M. L. Weingarten, T. N. Vemuri, P. | J Crit Care | 2021 |
AD-signature cortex |
| Effect of age on dexmedetomidine treatment for ventilated patients with sepsis: a post-hoc analysis of the DESIRE trial | Sato, T. Kawazoe, Y. Miyagawa, N. Yokokawa, Y. Kushimoto, S. Miyamoto, K. Ohta, Y. Morimoto, T. Yamamura, H. | Acute Med Surg | 2021 |
Delirium |
| Effects of comprehensive geriatric care models on postoperative outcomes in geriatric surgical patients: a systematic review and meta-analysis | Saripella, A. Wasef, S. Nagappa, M. Riazi, S. Englesakis, M. Wong, J. Chung, F. | BMC Anesthesiol | 2021 |
Adverse outcomes |
| Influence of Age on Postoperative Neurological Outcomes after Surgery of Acute Type A Aortic Dissection | Salem, M. Salib, M. Friedrich, C. Salem, M. Puehler, T. Schoettler, J. Schoeneich, F. Cremer, J. Haneya, A. | J Clin Med | 2021 |
acute type A aortic dissection |
| Associations between caregiver-detected delirium and symptoms of depression and anxiety in family caregivers of critically ill patients: a cross-sectional study | Rosgen, B. K. Krewulak, K. D. Davidson, J. E. Ely, E. W. Stelfox, H. T. Fiest, K. M. | BMC Psychiatry | 2021 |
Adult |
| A Core Outcome Set for Research Evaluating Interventions to Prevent and/or Treat Delirium in Critically Ill Adults: An International Consensus Study (Del-COrS) | Rose, L. Burry, L. Agar, M. Campbell, N. L. Clarke, M. Lee, J. Marshall, J. C. Devlin, J. W. Blackwood, B. Needham, D. M. Siddiqi, N. Page, V. | Crit Care Med | 2021 | |
| Postoperative delirium is associated with decreased recovery of ambulation one-month after surgery | Robinson, T. N. Kovar, A. Carmichael, H. Overbey, D. M. Goode, C. M. Jones, T. S. | Am J Surg | 2021 |
Aged |
| Emergence delirium in children: a Brazilian survey | Quintão, V. C. Sales, C. K. O. Herrera, E. M. Ellerkmann, R. K. Rosen, H. D. Carmona, M. J. C. | Braz J Anesthesiol | 2021 |
Anesthesia |
| Perioperative dexmedetomidine administration to prevent delirium in adults after non-cardiac surgery: A systematic review and meta-analysis | Qin, C. Jiang, Y. Lin, C. Li, A. Liu, J. | J Clin Anesth | 2021 |
Adult |
| Probable Delirium as a Risk Factor for Adverse Surgical Outcomes in Geriatric Patients With Acute Hip Fracture: Preoperative Assessment Using a Short Screening Tool | Perkins, J. L. Perera, S. Beach, M. Esper, S. A. Gruen, G. S. Neft, M. | AANA J | 2021 |
Adverse outcomes |
| Cognitive Stimulation in an Intensive Care Unit: A Qualitative Evaluation of Barriers to and Facilitators of Implementation | Parker, A. M. Aldabain, L. Akhlaghi, N. Glover, M. Yost, S. Velaetis, M. Lavezza, A. Mantheiy, E. Albert, K. Needham, D. M. | Crit Care Nurse | 2021 | |
| Does Delirium Phenomenology in Persons with Advanced Cancer Follow a Specific Pattern? | Pallotti, M. C. Lopez-Fidalgo, J. Centeno, C. Celin, D. Biasco, G. Giovannini, M. Maltoni, M. Noguera, A. | J Palliat Med | 2021 |
Mdas |
| Dexmedetomidine, Delirium, and Adverse Outcomes: Analysis of the STS Adult Cardiac Surgery Database | Pal, N. Abernathy, J. H., 3rd Taylor, M. A. Bollen, B. A. Shah, A. S. Feng, X. Shotwell, M. S. Kertai, M. D. | Ann Thorac Surg | 2021 |
cardiac surgery |
| Factors associated with delirium after cardiac surgery: A prospective cohort study | Ordóñez-Velasco, L. M. Hernández-Leiva, E. | Ann Card Anaesth | 2021 |
Body mass index |
| Baseline sleep as a predictor of delirium after surgical aortic valve replacement: A feasibility study | Oldham, M. A. Pigeon, W. R. Chapman, B. Yurcheshen, M. Knight, P. A. Lee, H. B. | Gen Hosp Psychiatry | 2021 |
Apnea/hypopnea index |
| What Does a Diagnosis of Depression Mean for Patients Undergoing Colorectal Surgery? | Oduyale, O. K. Eltahir, A. A. Stem, M. Prince, E. Zhang, G. Q. Safar, B. Efron, J. E. Atallah, C. | J Surg Res | 2021 |
Colorectal surgery |
| A randomized double-blind placebo-controlled trial of intravenous thiamine for prevention of delirium following allogeneic hematopoietic stem cell transplantation | Nakamura, Z. M. Deal, A. M. Park, E. M. Quillen, L. J. Chien, S. A. Stanton, K. E. McCabe, S. D. Heiling, H. M. Wood, W. A. Shea, T. C. Rosenstein, D. L. | J Psychosom Res | 2021 |
Cognitive impairment |
| The 4-DSD: A New Tool to Assess Delirium Superimposed on Moderate to Severe Dementia | Morandi, A. Grossi, E. Lucchi, E. Zambon, A. Faraci, B. Severgnini, J. MacLullich, A. Smith, H. Pandharipande, P. Rizzini, A. Galeazzi, M. Massariello, F. Corradi, S. Raccichini, A. Scrimieri, A. Morichi, V. Gentile, S. Lucchini, F. Pecorella, L. Mossello | J Am Med Dir Assoc | 2021 |
Delirium |
| Are dexmedetomidine and olanzapine suitable to control delirium in critically ill elderly patients? A retrospective cohort study | Liu, S. Zhao, R. Yang, R. Zhao, H. Ji, C. Duan, M. Liu, J. | Biomed Pharmacother | 2021 |
Critical illness |
| Association between glucose variability and postoperative delirium in acute aortic dissection patients: an observational study | Lin, Y. J. Lin, L. Y. Peng, Y. C. Zhang, H. R. Chen, L. W. Huang, X. Z. Chen, Q. | J Cardiothorac Surg | 2021 |
Acute Disease |
| Frailty is associated with a higher risk of developing delirium and cognitive impairment among patients with diabetic kidney disease: A longitudinal population-based cohort study | Lee, S. Y. Wang, J. Chao, C. T. Chien, K. L. Huang, J. W. | Diabet Med | 2021 |
chronic kidney disease |
| Multi-Component Care Bundle in Geriatric Fracture Hip for Reducing Post-Operative Delirium | Lam, D. M. H. Wang, C. Lee, A. K. H. Chung, Y. F. Lau, T. W. Fang, C. Leung, F. Chan, T. C. W. | Geriatr Orthop Surg Rehabil | 2021 |
delirium |
| Occurrence of Delirium during ECMO Therapy in a Critical Care Unit in Poland-A Cross-Sectional Pilot Study | Krupa, S. Friganovic, A. Mędrzycka-Dąbrowska, W. | Int J Environ Res Public Health | 2021 |
Critical Care |
| Steroids to reduce the impact on delirium (STRIDE): a double-blind, randomised, placebo-controlled feasibility trial of pre-operative dexamethasone in people with hip fracture | Kluger, M. T. Skarin, M. Collier, J. Rice, D. A. McNair, P. J. Seow, M. Y. Connolly, M. J. | Anaesthesia | 2021 |
delirium |
| Elevated plasma levels of galectin-3 binding protein are associated with post-stroke delirium - A pilot study | Klimiec-Moskal, E. Pasinska, P. Kowalska, K. Klimkowicz-Mrowiec, A. Pera, J. Slowik, A. Dziedzic, T. | J Neuroimmunol | 2021 |
Delirium |
| Postoperative delirium after cardiac surgery of elderly patients as an independent risk factor for prolonged length of stay in intensive care unit and in hospital | Kirfel, A. Menzenbach, J. Guttenthaler, V. Feggeler, J. Mayr, A. Coburn, M. Wittmann, M. | Aging Clin Exp Res | 2021 |
Cardiac surgery |
| ED-DEL: Development of a change package and toolkit for delirium in the emergency department | Kennedy, M. Webb, M. Gartaganis, S. Hwang, U. Biese, K. Stuck, A. Lesser, A. Hshieh, T. Inouye, S. K. | J Am Coll Emerg Physicians Open | 2021 |
aging |
| Elevated Monocyte Chemoattractant Protein-1 as the Independent Risk Factor of Delirium after Cardiac Surgery. A Prospective Cohort Study | Kaźmierski, J. Miler, P. Pawlak, A. Jerczyńska, H. Woźniak, J. Frankowska, E. Brzezińska, A. Woźniak, K. Krejca, M. Wilczyński, M. | J Clin Med | 2021 |
cardiac surgery |
| Prevalence of and factors associated with physical restraint use in the intensive care unit: a multicenter prospective observational study in Japan | Kawai, Y. Hamamoto, M. Miura, A. Yamaguchi, M. Masuda, Y. Iwata, M. Kanbe, M. Ikematsu, Y. | Intern Emerg Med | 2021 |
Associated factors |
| Added value of anxiolytic benzodiazepines in predictive models on severe delirium in patients with acute decompensated heart failure: A retrospective analysis | Kawada, K. Fukuda, H. Kubo, T. Ohta, T. Ishida, T. Morisawa, S. Kawazoe, T. Okamoto, M. Fujita, H. Jobu, K. Morita, Y. Ueba, T. Kitaoka, H. Miyamura, M. | PLoS One | 2021 | |
| Sagittal alignment changes and postoperative complications following surgery for adult spinal deformity in patients with Parkinson's disease: a multi-institutional retrospective cohort study | Kawabata, A. Yoshii, T. Sakai, K. Hirai, T. Yuasa, M. Inose, H. Matsukura, Y. Morishita, S. Tomori, M. Torigoe, I. Kusano, K. Otani, K. Arai, Y. Shindo, S. Okawa, A. | BMC Musculoskelet Disord | 2021 |
Follow-Up Studies |
| Factors associated with post-electroconvulsive therapy delirium: A retrospective chart review study | Jo, Y. T. Joo, S. W. Lee, J. Joo, Y. H. | Medicine (Baltimore) | 2021 |
Adult |
| Association of Delirium during Critical Illness With Mortality: Multicenter Prospective Cohort Study | Hughes, C. G. Hayhurst, C. J. Pandharipande, P. P. Shotwell, M. S. Feng, X. Wilson, J. E. Brummel, N. E. Girard, T. D. Jackson, J. C. Ely, E. W. Patel, M. B. | Anesth Analg | 2021 | |
| Validating the Mandarin version of the Memorial delirium assessment scale in general medical hospital patients | Hu, C. H. Chiu, Y. C. Liu, S. I. Ko, K. T. | Asia Pac Psychiatry | 2021 |
confusion assessment method |
| How do delirium motor subtypes differ in phenomenology and contributory aetiology? a cross-sectional, multisite study of liaison psychiatry and palliative care patients | Glynn, K. McKenna, F. Lally, K. O'Donnell, M. Grover, S. Chakrabarti, S. Avasthi, A. Mattoo, S. K. Sharma, A. Gosh, A. Shah, R. Hickey, D. Fitzgerald, J. Davis, B. O'Regan, N. Adamis, D. Williams, O. Awan, F. Dunne, C. Cullen, W. McInerney, S. McFarland, | BMJ Open | 2021 |
Adult |
| Frailty, post-operative delirium and functional status at discharge in patients with hip fracture | Gandossi, C. M. Zambon, A. Oliveri, G. Codognola, M. Szabo, H. Cazzulani, I. Ferrara, M. C. Mottadelli, C. Galeazzi, M. Amoroso, I. Zarcone, C. Principato, G. Corsi, M. Mazzola, P. Zatti, G. Foti, G. Bellelli, G. | Int J Geriatr Psychiatry | 2021 |
delirium |
| The Safety and Efficacy Evaluation of Dexmedetomidine for Procedural Sedation and Postoperative Behaviors in Pediatric Populations: A Systematic Review and Meta-analysis | Gan, L. Zhao, X. Chen, X. | Ann Pharmacother | 2021 |
delirium |
| Association between frailty and postoperative delirium: a meta-analysis of cohort study | Fu, D. Tan, X. Zhang, M. Chen, L. Yang, J. | Aging Clin Exp Res | 2021 |
Cohort studies |
| Incidence and factors associated with delirium in children in a single pediatric intensive care unit in Brazil | Flores, A. E. R. Oura, K. H. U. Rocha, P. K. Belela-Anacleto, A. S. C. Kusahara, D. M. | J Pediatr Nurs | 2021 |
Delirium |
| Long-Term Outcomes in Intensive Care Unit Patients with Delirium: A Population-Based Cohort Study | Fiest, K. M. Soo, A. Hee Lee, C. Niven, D. J. Ely, E. W. Doig, C. J. Stelfox, H. T. | Am J Respir Crit Care Med | 2021 |
critical care |
| Impact of Religiosity on Delirium Severity Among Critically Ill Shi'a Muslims: A Prospective Multi-Center Observational Study | Farzanegan, B. Elkhatib, T. H. M. Elgazzar, A. E. Moghaddam, K. G. Torkaman, M. Zarkesh, M. Goharani, R. Bashar, F. R. Hajiesmaeili, M. Shojaei, S. Madani, S. J. Vahedian-Azimi, A. Hatamian, S. Mosavinasab, S. M. M. Khoshfetrat, M. Khatir, A. K. Miller, A | J Relig Health | 2021 |
Critical Illness |
| Depression as a predictor of postoperative delirium after cardiac surgery: a systematic review and meta-analysis | Falk, A. Kåhlin, J. Nymark, C. Hultgren, R. Stenman, M. | Interact Cardiovasc Thorac Surg | 2021 |
Cardiac surgery |
| The delirium screening tool 4AT in routine clinical practice: prediction of mortality, sensitivity and specificity | Evensen, S. Hylen Ranhoff, A. Lydersen, S. Saltvedt, I. | Eur Geriatr Med | 2021 |
4at |
| Delirium and Associated Length of Stay and Costs in Critically Ill Patients | Dziegielewski, C. Skead, C. Canturk, T. Webber, C. Fernando, S. M. Thompson, L. H. Foster, M. Ristovic, V. Lawlor, P. G. Chaudhuri, D. Dave, C. Herritt, B. Bush, S. H. Kanji, S. Tanuseputro, P. Thavorn, K. Rosenberg, E. Kyeremanteng, K. | Crit Care Res Pract | 2021 | |
| Opioid Use Increases the Risk of Delirium in Critically Ill Adults Independently of Pain | Duprey, M. S. Dijkstra-Kersten, S. M. A. Zaal, I. J. Briesacher, B. A. Saczynski, J. S. Griffith, J. L. Devlin, J. W. Slooter, A. J. C. | Am J Respir Crit Care Med | 2021 |
delirium |
| Association Between Incident Delirium Treatment With Haloperidol and Mortality in Critically Ill Adults | uprey, M. S. Devlin, J. W. van der Hoeven, J. G. Pickkers, P. Briesacher, B. A. Saczynski, J. S. Griffith, J. L. van den Boogaard, M. | Crit Care Med | 2021 | |
| Descriptive analysis of the unwarranted continuation of antipsychotics for the management of ICU delirium during transitions of care: A multicenter evaluation across New Jersey | Dixit, D. Andrews, L. B. Radparvar, S. Adams, C. Kumar, S. T. Cardinale, M. | Am J Health Syst Pharm | 2021 |
ICU delirium |
| Cluster nursing can reduce postoperative delirium and improve the negative emotions and quality of life of elderly ICU patients | Di, J. Wang, X. Chen, J. | Am J Transl Res | 2021 |
Cluster nursing |
| Cluster nursing can reduce postoperative delirium and improve the negative emotions and quality of life of elderly ICU patients | Di, J. Wang, X. Chen, J. | Am J Transl Res | 2021 |
Cluster nursing |
| Influence of intraoperative and postoperative factors on the predictive capacity of the delirium risk model for cardiac surgery patients (DELIPRECAS): An observational multicentre study | de la Varga-Martínez, O. Gómez-Pesquera, E. Muñoz-Moreno, M. F. Marcos-Vidal, J. M. López-Gómez, A. Rodenas-Gómez, F. Ramasco, F. Álvarez-Refojo, F. Barón, M. S. Tamayo, E. Heredia-Rodríguez, M. Gómez-Sánchez, E. | J Clin Anesth | 2021 |
Cardiac Surgical Procedures/adverse effects |
| Older trauma patients are at high risk of delirium, especially those with underlying dementia or baseline frailty | Ní Chróinín D Francis, N. Wong, P. Kim, Y. D. Nham, S. D'Amours, S. | Trauma Surg Acute Care Open | 2021 |
cognition |
| The Impact of Monitoring Depth of Anesthesia and Nociception on Postoperative Cognitive Function in Adult Multiple Trauma Patients | Cotae, A. M. Ţigliş, M. Cobilinschi, C. Băetu, A. E. Iacob, D. M. Grinţescu, I. M. | Medicina (Kaunas) | 2021 |
Adult |
| Outcomes of trimodality CROSS regimen in older adults with locally advanced esophageal cancer | Cooper, L. Dezube, A. R. De León, L. E. Kucukak, S. Mazzola, E. Dumontier, C. Mamon, H. Enzinger, P. Jaklitsch, M. T. Frain, L. N. Wee, J. O. | Eur J Surg Oncol | 2021 |
Cross |
| Nursing intervention to prevent delirium in critically ill adults | Contreras, C. C. T. Páez-Esteban, A. N. Rincon-Romero, M. K. Carvajal, R. R. Herrera, M. M. Castillo, Ahdd | Rev Esc Enferm USP | 2021 | |
| Changes in Sedation Practices in Association with Delirium Screening in Infants After Cardiopulmonary Bypass | Chomat, M. R. Said, A. S. Mann, J. L. Wallendorf, M. Bickhaus, A. Figueroa, M. | Pediatr Cardiol | 2021 |
Cornell Assessment of Pediatric Delirium |
| Risk factors of postoperative delirium after cardiac surgery: a meta-analysis | Chen, H. Mo, L. Hu, H. Ou, Y. Luo, J. | J Cardiothorac Surg | 2021 |
Age Factors |
| Diagnosis of overweight or obese malnutrition spells DOOM for hip fracture patients: A prospective audit | Bell, J. J. Pulle, R. C. Lee, H. B. Ferrier, R. Crouch, A. Whitehouse, S. L. | Clin Nutr | 2021 |
Body mass index |
| Risk factors for delirium among hospitalized patients in Zambia | Mateyo, K. Yan, Y. Liu, D. Zuo, Y. Di Gravio, C. Thome, J. C. Riviello, E. D. Saylor, D. Ely, E. W. Heimburger, D. C. | PLoS One | 2021 | |
| Risk factors associated with treatment of hyperactive postoperative delirium in elderly patients following hip fracture surgery under regional anesthesia: a nationwide population-based study | Ahn, E. J. Bang, S. R. | Braz J Anesthesiol | 2021 |
Anesthesia |
| Incidence of delirium in the critical care unit and risk factors in the Central Region, Saudi Arabia | Abazid, R. M. Al-Harbi, S. A. Allihimy, A. S. Aldrewesh, D. A. Alkuraydis, S. A. Alhammad, I. M. Elbashir, A. Y. Widyan, A. M. Abohamr, S. I. | Saudi Med J | 2021 |
Saudi |
| The risk factors of postoperative delirium in patients with hip fracture: implication for clinical management | Xu, W. Ma, H. Li, W. Zhang, C. | BMC Musculoskelet Disord | 2021 |
Delirium/diagnosis/epidemiology/etiology |
| Nationwide mortality trends of delirium in Australia and the United States from 2006 to 2016 | Wu, H. Mach, J. Le Couteur, D. G. Hilmer, S. N. | Australas J Ageing | 2021 |
delirium |
| The Use of Near-Infrared Spectroscopy and/or Transcranial Doppler as Non-Invasive Markers of Cerebral Perfusion in Adult Sepsis Patients With Delirium: A Systematic Review | Wood, M. D. Boyd, J. G. Wood, N. Frank, J. Girard, T. D. Ross-White, A. Chopra, A. Foster, D. Griesdale, D. E. G. | J Intensive Care Med | 2021 |
cerebral autoregulation |
| Midazolam Premedication Immediately Before Surgery Is Not Associated With Early Postoperative Delirium | Wang, M. L. Min, J. Sands, L. P. Leung, J. M. | Anesth Analg | 2021 | |
| The Effect of a Quality Improvement Intervention on Sleep and Delirium in Critically Ill Patients in a Surgical ICU | Tonna, J. E. Dalton, A. Presson, A. P. Zhang, C. Colantuoni, E. Lander, K. Howard, S. Beynon, J. Kamdar, B. B. | Chest | 2021 |
critical care |
| Association between components of the delirium syndrome and outcomes in hospitalised adults: a systematic review and meta-analysis | Tieges, Z. Quinn, T. MacKenzie, L. Davis, D. Muniz-Terrera, G. MacLullich, A. M. J. Shenkin, S. D. | BMC Geriatr | 2021 |
Cognition |
| The Prognostic Performance of Frailty for Delirium and Functional Decline in Vascular Surgery Patients | Thillainadesan, J. Mudge, A. M. Aitken, S. J. Hilmer, S. N. Cullen, J. S. Yumol, M. F. Close, J. C. T. Norris, C. M. Kerdic, R. Naganathan, V. | J Am Geriatr Soc | 2021 |
delirium |
| Efficacy of quetiapine for delirium prevention in hospitalized older medical patients: a randomized double-blind controlled trial | Thanapluetiwong, S. Ruangritchankul, S. Sriwannopas, O. Chansirikarnjana, S. Ittasakul, P. Ngamkala, T. Sukumalin, L. Charernwat, P. Saranburut, K. Assavapokee, T. | BMC Geriatr | 2021 |
Aged |
| Effects of Slowness, Frailty, Insufficient Intake, and Delirium in Patients Following Cardiac Surgery: A Cohort Study | Teng, C. H. Hsu, R. B. Chi, N. H. Wang, S. S. Chen, Y. S. Chen, S. Y. Chen, C. C. | J Cardiovasc Nurs | 2021 | |
| Factors associated with the severity of delirium | Tachibana, M. Inada, T. Ichida, M. Kojima, S. Shioya, M. Wakayama, K. Ozaki, N. | Hum Psychopharmacol | 2021 |
Drs-r98 |
| Screening for delirium in the intensive care unit using eDIS-ICU - A purpose-designed app: A pilot study | Sutt, A. L. Flaws, D. Gunn, H. Eeles, E. Lye, I. Irvine, L. Patterson, S. Bagshaw, T. O'Luanaigh, C. Tronstad, O. Fraser, J. | Aust Crit Care | 2021 |
Delirium |
| Association Among Preoperative Cognitive Performance, Regional Cerebral Oxygen Saturation, and Postoperative Delirium in Older Portuguese Patients | Susano, M. J. Dias, M. Seixas, F. S. Vide, S. Grasfield, R. Abelha, F. J. Crosby, G. Culley, D. J. Amorim, P. | Anesth Analg | 2021 |
Age Factors |