NIDUS Delirium Bibliography

Delirium Bibliography books graphic What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!

How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.

Reference Information

Title: Using simulated family presence to decrease agitation in older hospitalized delirious patients: A randomized controlled trial.

Authors: Waszynski, Christine M. Milner, Kerry A. Staff, Ilene Molony, Sheila L.

Year: 2018

Journal: International Journal of Nursing Studies

Abstract: Background Simulated family presence has been shown to be an effective nonpharmacological intervention to reduce agitation in persons with dementia in nursing homes. Hyperactive or mixed delirium is a common and serious complication experienced by hospitalized patients, a key feature of which is agitation. Effective nonpharmacological interventions to manage delirium are needed. Objectives To examine the effect of simulated family presence through pre-recorded video messages on the agitation level of hospitalized, delirious, acutely agitated patients. Design Single site randomized control trial, 3 groups × 4 time points mixed factorial design conducted from July 2015 to March 2016. Setting Acute care level one trauma center in an inner city of the state of Connecticut, USA. Participants Hospitalized patients experiencing hyperactive or mixed delirium and receiving continuous observation were consecutively enrolled (n = 126), with 111 participants completing the study. Most were older, male, Caucasian, spouseless, with a pre-existing dementia. Methods Participants were randomized to one of the following study arms: view a one minute family video message, view a one minute nature video, or usual care. Participants in experimental groups also received usual care. The Agitated Behavior Scale was used to measure the level of agitation prior to, during, immediately following, and 30 min following the intervention. Results Both the family video and nature video groups displayed a significant change in median agitation scores over the four time periods ( p < 0.001), whereas the control group did not. The family video group had significantly lower median agitation scores during the intervention period (p < 0.001) and a significantly greater proportion (94%) of participants experiencing a reduction in agitation from the pre-intervention to during intervention ( p < 0.001) than those viewing the nature video (70%) or those in usual care only (30%). The median agitation scores for the three groups were not significantly different at either of the post intervention time measurements. When comparing the proportion of participants experiencing a reduction in agitation from baseline to post intervention, there remained a statistically significant difference (p = 0.001) between family video(60%) and usual care (35.1%) immediately following the intervention Conclusion This work provides preliminary support for the use of family video messaging as a nonpharmacological intervention that may decrease agitation in selected hospitalized delirious patients. Further studies are necessary to determine the efficacy of the intervention as part of a multi-component intervention as well as among younger delirious patients without baseline dementia.

PMID: 29100197

Keywords: Dementia
Nursing Homes
Presence
Family
Agitation — Prevention and Control
Human
Randomized Controlled Trials
Connecticut
Delirium
Videorecording

Page(s): 154-61

Volume: 77

Issue

Total Records Found: 6289, showing 100 per page
Title	Authors	Journal	Year	Keywords
Case-control study on the interplay between immunoparalysis and delirium after cardiac surgery	CheheiliSobbi, S. Peters van Ton, A. M. Wesselink, E. M. Looije, M. F. Gerretsen, J. Morshuis, W. J. Slooter, A. J. C. Abdo, W. F. Pickkers, P. van den Boogaard, M.	J Cardiothorac Surg	2021	Cardiac Surgical Procedures/adverse effects Case-Control Studies Cytokines Delirium/etiology Humans Prospective Studies Tumor Necrosis Factor-alpha Cardiothoracic surgery Delirium Immunity Intensive care medicine
Diagnostic accuracy of the "4 A's Test" delirium screening tool for the postoperative cardiac surgery ward	Chang, Y. Ragheb, S. M. Oravec, N. Kent, D. Nugent, K. Cornick, A. Hiebert, B. Rudolph, J. L. MacLullich, A. M. J. Arora, R. C.	J Thorac Cardiovasc Surg	2021	4at cardiac surgery nursing postoperative delirium
Meta-analysis of ICU Delirium Biomarkers and Their Alignment With the NIA-AA Research Framework	Chan, C. K. Song, Y. Greene, R. Lindroth, H. Khan, S. Rios, G. Khan, B. Wang, S	Am J Crit Care	2021	Alzheimer Disease Biomarkers Delirium/diagnosis Humans Intensive Care Units National Institute on Aging (U.S.) United States
Sedation strategy and ICU delirium: a multicentre, population-based propensity score-matched cohort study	Casault, C. Soo, A. Lee, C. H. Couillard, P. Niven, D. Stelfox, T. Fiest, K.	BMJ Open	2021	Adult Alberta Cohort Studies Delirium/chemically induced/epidemiology Female Humans Hypnotics and Sedatives/adverse effects Intensive Care Units Length of Stay Male Middle Aged Propensity Score Respiration, Artificial Retrospective Studies adult intensive & critical care delirium & cognitive disorders health & safety quality in health care
Health outcomes after the implementation of multidisciplinary clinical guidelines for the care of hip fractures	Casanova Querol, T. Santiago Bautista, J. M. Lafuente Salinas, M. Güell Farré, E. Girós Torres, J. Martín-Baranera, M. Miralles Basseda, R.	Rev Clin Esp (Barc)	2021	Atención continuada Continued care Fractura de cadera Hip fracture Internal Medicine Medicina Interna Orthogeriatrics Ortogeriatría
Pharmacological and non-pharmacological interventions to prevent delirium in critically ill patients: a systematic review and network meta-analysis	Burry, L. D. Cheng, W. Williamson, D. R. Adhikari, N. K. Egerod, I. Kanji, S. Martin, C. M. Hutton, B. Rose, L.	Intensive Care Med	2021	Adult Bayes Theorem Critical Illness Delirium/prevention & control Humans Network Meta-Analysis Randomized Controlled Trials as Topic Respiration, Artificial/adverse effects Critical care Delirium Non-pharmacological interventions Pharmacological *Prevention financial relationships with any organizations that might have an interest in the submitted work in the previous 3 years no other relationships or activities that could appear to have influenced the submitted work. BH has previously provided methodologic advice to Eversana Inc for the conduct of systemic reviews and meta-analysis on unrelated topics.
Dexmedetomidine for Facilitating Mechanical Ventilation Extubation in Difficult-to-Wean ICU Patients: Systematic Review and Meta-Analysis of Clinical Trials	Buckley, M. S. Smithburger, P. L. Wong, A. Fraser, G. L. Reade, M. C. Klein-Fedyshin, M. Ardiles, T. Kane-Gill, S. L.	J Intensive Care Med	2021	Adult Airway Extubation Critical Care Dexmedetomidine Humans Intensive Care Units Length of Stay Respiration, Artificial agitation delirium dexmedetomidine extubation intensive care mechanical ventilation weaning
Risk factors for postoperative delirium: An umbrella review of systematic reviews	Bramley, P. McArthur, K. Blayney, A. McCullagh, I.	Int J Surg	2021	Cognitive Dysfunction Delirium/epidemiology/etiology Humans Length of Stay Postoperative Complications/epidemiology/etiology Risk Factors Systematic Reviews as Topic Delirium Prognostic Risk factor Surgery Umbrella review
Inadequate emergence after anesthesia for elective cancer surgery: a single-center cohort study	Braga, A. Abelha, F.	Braz J Anesthesiol	2021	Cancer surgeries Emergence delirium Hypoactive emergence Inadequate emergence Quality of recovery
Asthma and delirium episodes during hospitalization	Bozek, A. Fiolka, R. Zajac, M.	Aging Med (Milton)	2021	asthma delirium
A pragmatic assessment of proton pump inhibitors vs. histamine type 2 receptor antagonists on clinically important gastrointestinal bleeding and mortality when used for stress ulcer prophylaxis in the ICU	Boyd, C. Hassig, T. MacLaren, R.	Pharmacotherapy	2021	critical illness delirium histamine H2 antagonists mortality peptic ulcer prevention and control proton pump inhibitors stress
Brain Network Dysfunction in Poststroke Delirium and Spatial Neglect: An fMRI Study	Boukrina, O. Kowalczyk, M. Koush, Y. Kong, Y. Barrett, A. M.	Stroke	2021	MRI, functional attention basal ganglia delirium incidence ischemic stroke prevalence
Preventing Delirium and Promoting Long-Term Brain Health: A Clinical Trial Design for the Perioperative Cognitive Enhancement (PROTECT) Trial	Atkins, K. J. Scott, D. A. Silbert, B. Pike, K. E. Evered, L.	J Alzheimers Dis	2021	Anesthesia and analgesia cognition delirium dementia healthy aging perioperative medicine prehabilitation preventive medicine rehabilitation
Prevalence of Severe Neurocognitive Impairment and Its Association with Socio-Demographics and Functionality Among Ugandan Older Persons: A Hospital-Based Study	Atim, L. M. Kaggwa, M. M. Mamun, M. A. Ashaba, S. Maling, S.	Clin Interv Aging	2021	Aged Aged, 80 and over *Cognition Disorders Cross-Sectional Studies Female Hospitals Humans Male Middle Aged Prevalence Uganda/epidemiology Barthel Index Mini-Mental Status Examination Ugandan elderly dementia early diagnosis functionality neurocognitive disorder prevalence and associated factors
Clinical Aspects of Palliative Sedation in Prospective Studies. A Systematic Review	Arantzamendi, M. Belar, A. Payne, S. Rijpstra, M. Preston, N. Menten, J. Van der Elst, M. Radbruch, L. Hasselaar, J. Centeno, C.	J Pain Symptom Manage	2021	Hospice and Palliative Care Nursing Humans Hypnotics and Sedatives/therapeutic use Palliative Care Prospective Studies Retrospective Studies Terminal Care Palliative sedation deep sedation hospice care palliative care palliative medicine prospective studies sedation systematic review *terminally ill
Psychometric Properties of Nursing Delirium Screening Scale in Patients Admitted to Intensive Care Units	Amirajam, Z. Asadi-Noran, E. Molaei, B. Adiban, V. Heidarzadeh, M. Hassanpour-Darghah, M.	Indian J Crit Care Med	2021	Delirium Intensive care Validity
Delirium researchers' perspectives of the challenges in delirium biomarker research: A qualitative study	Amgarth-Duff, I. Hosie, A. Caplan, G. A. Agar, M.	PLoS One	2021	Biomarkers/blood Biomedical Research Delirium/blood Female Humans Male Qualitative Research Research Personnel
Addition of Valerian and Lemon Balm Extract to Quetiapine Reduces Agitation in Critically Ill Patients with Delirium: A Pilot Randomized Clinical Trial	Alikiaie, B. Shahmoradi, E. Yekdaneh, A. Mousavi, S.	Indian J Crit Care Med	2021	Delirium Lemon balm Quetiapine Valerian
Spinal block and delirium in oncologic patients after laparoscopic surgery in the Trendelenburg position: A randomized controlled trial	Mitsunaga, J. K. Junior Calsavara, V. F. Onari, E. S. Arantes, V. M. Akamine, C. P. Handa, A. M. Quezada, M. M. C. Ito, F. Y. Porto, A. C. S. Giroud Joaquim, E. H. Nakamura, G.	PLoS One	2021
Perioperative Vascular Biomarker Profiling in Elective Surgery Patients Developing Postoperative Delirium: A Prospective Cohort Study	Menzenbach, J. Frede, S. Petras, J. Guttenthaler, V. Kirfel, A. Neumann, C. Mayr, A. Wittmann, M. Coburn, M. Klaschik, S. Hilbert, T.	Biomedicines	2021	Ccl2 Mcp-1 biomarker cardiac surgery elective surgery glycocalyx postoperative delirium vascular inflammation
Preliminary Study of Serum Biomarkers Associated With Delirium After Major Cardiac Surgery	McKay, T. B. Rhee, J. Colon, K. Adelsberger, K. Turco, I. Mueller, A. Qu, J. Akeju, O.	J Cardiothorac Vasc Anesth	2021	Fgf cardiac surgery cardiopulmonary bypass cognition delirium fibroblast growth factor inflammation metabolism neurodegeneration
Stratified delirium risk using prescription medication data in a state-wide cohort	McCoy, T. H., Jr. Castro, V. M. Hart, K. L. Perlis, R. H.	Gen Hosp Psychiatry	2021	Cohort study Data mining Delirium Feature engineering Pharmacovigilance Predictive modeling
Nutritional Risk at intensive care unit admission and outcomes in survivors of critical illness	Mart, M. F. Girard, T. D. Thompson, J. L. Whitten-Vile, H. Raman, R. Pandharipande, P. P. Heyland, D. K. Ely, E. W. Brummel, N. E.	Clin Nutr	2021	Activities of daily living Cognitive dysfunction Critical illness Nutrition assessment Patient discharge Quality of life
Risk Factors for Delirium Are Different in the Very Old: A Comparative One-Year Prospective Cohort Study of 5,831 Patients	Marquetand, J. Bode, L. Fuchs, S. Hildenbrand, F. Ernst, J. von Kaenel, R. Boettger, S.	Front Psychiatry	2021	comparison delirium prospective risk factors very old
Plasma interleukin-6 is a potential predictive biomarker for postoperative delirium among acute type a aortic dissection patients treated with open surgical repair	Lv, X. C. Lin, Y. Wu, Q. S. Wang, L. Hou, Y. T. Dong, Y. Chen, L. W.	J Cardiothorac Surg	2021	Adult Aged Aneurysm, Dissecting/ surgery Aortic Aneurysm/ surgery Area Under Curve Biomarkers/blood Delirium/ blood/etiology Humans Interleukin-6/ blood Male Middle Aged Postoperative Complications/blood/etiology ROC Curve Retrospective Studies Aortic dissection Inflammatory cytokines Interleukin-6 Postoperative delirium
Association of early and later depressive symptoms with functional outcome after ischemic stroke	Lopatkiewicz, A. M. Pera, J. Slowik, A. Dziedzic, T.	J Neural Transm (Vienna)	2021	Cognitive decline Delirium Depression Outcome Stroke
Development and validation of a postoperative delirium prediction model for pediatric patients: A prospective, observational, single-center study	Lin, N. Liu, K. Feng, J. Chen, R. Ying, Y. Lv, D. Zhou, Y. Xu, H.	Medicine (Baltimore)	2021	Adolescent Anesthesia, General/ adverse effects/methods Child Child, Preschool Developmental Disabilities/ epidemiology Dexmedetomidine/administration & dosage/ adverse effects Emergence Delirium/ epidemiology/etiology/prevention & control Female Humans Hypnotics and Sedatives/administration & dosage/ adverse effects Infant Infant, Newborn Logistic Models Male Prevalence Prospective Studies ROC Curve Risk Assessment/methods/statistics & numerical data Risk Factors
Patients' experiences of delirium: A systematic review and meta-summary of qualitative research	Kuusisto-Gussmann, E. Höckelmann, C. von der Lühe, V. Schmädig, R. Baltes, M. Stephan, A.	J Adv Nurs	2021	delirium nursing qualitative research systematic review
Effects of case-based confusion assessment methods for intensive care unit training on delirium knowledge and delirium assessment accuracy of intensive care units: A quasi-experimental study	Kim, Y. N. Kim, D. H.	Nurse Educ Today	2021	Critical Illness Delirium/diagnosis Hospitals, University Humans Intensive Care Units Republic of Korea Assessment Delirium Education Intensive care unit Knowledge Nursing
Bridging the Gap Between the Intensive Care Unit and the Acute Medical Care Unit	Kim, E. Kast, C. Afroz-Hossain, A. Qiu, M. Pappas, K. Sinvani, L.	Am J Crit Care	2021
Preoperative MRI brain phenotypes are related to postoperative delirium in older individuals	Kant, I. M. J. Slooter, A. J. C. Jaarsma-Coes, M. van Montfort, S. J. T. Witkamp, T. D. Pasma, W. Hendrikse, J. de Bresser, J.	Neurobiol Aging	2021	Brain phenotypes Delirium Encephalopathy Mri
Pre-Existing Psychiatric Illness Is Associated With an Increased Risk of Delirium in Patients With Acute Respiratory Distress Syndrome	Kalra, S. S. Jaber, J. Alzghoul, B. N. Hyde, R. Parikh, S. Urbine, D. Reddy, R.	J Intensive Care Med	2021	Ards acute respiratory distress syndrome anxiety delirium depression psychiatric illness
Development and internal validation of a predictive model of cognitive decline 36 months following elective surgery	Jones, R. N. Tommet, D. Steingrimsson, J. Racine, A. M. Fong, T. G. Gou, Y. Hshieh, T. T. Metzger, E. D. Schmitt, E. M. Tabloski, P. A. Travison, T. G. Vasunilashorn, S. M. Abdeen, A. Earp, B. Kunze, L. Lange, J. Vlassakov, K. Dickerson, B. C. Marcantonio	Alzheimers Dement (Amst)	2021	cognitive decline delirium machine learning model prediction post‐operative statistical learning
The performance of the Dutch Safety Management System frailty tool to predict the risk of readmission or mortality in older hospitalised cardiac patients	Jepma, P. Verweij, L. Tijssen, A. Heymans, M. W. Flierman, I. Latour, C. H. M. Peters, R. J. G. Scholte Op Reimer, W. J. M. Buurman, B. M. Ter Riet, G.	BMC Geriatr	2021	Aged Aged, 80 and over Female Frailty Geriatric Assessment Humans Male Netherlands/epidemiology Patient Readmission Prospective Studies Risk Assessment Risk Factors Safety Management Cardiovascular diseases Mortality Predictive value of tests
Outcomes of transcatheter aortic valve replacement in patients with cognitive dysfunction	Jain, V. Kalra, A. Panhwar, M. S. Bansal, A. Nowacki, A. Bhatia, K. Gupta, T. Ineman, N. L. Khan, S. U. Krishnaswamy, A. Reed, G. W. Puri, R. Kapadia, S. R. Svensson, L. G. Kanaa, N. A. Lahorra, J. A.	J Am Geriatr Soc	2021	cognitive impairment dementia outcomes transcatheter aortic valve replacement
The Importance of Delirium and Delirium Prevention in Older Adults During Lockdowns	Inouye, S. K.	JAMA	2021	Aged COVID-19/ psychology Delirium/etiology/ prevention & control Hospitalization Humans Infection Control Inpatients/psychology Physical Distancing
Association of Pain With Atrial Fibrillation and Delirium After Cardiac Surgery: A DECADE Sub-Study	Ince, I. Chiu, A. Sagir, A. Chahar, P. Lin, J. Douglas, A. Adi, A. Fang, J. Mao, G. Turan, A.	J Cardiothorac Vasc Anesth	2021	atrial fibrillation delirium pain
Higher versus lower mean arterial pressure target management in older patients having non-cardiothoracic surgery: A prospective randomized controlled trial	Hu, A. M. Qiu, Y. Zhang, P. Zhao, R. Li, S. T. Zhang, Y. X. Zheng, Z. H. Hu, B. L. Yang, Y. L. Zhang, Z. J.	J Clin Anesth	2021	Aged Anesthesia, General/adverse effects Arterial Pressure Delirium/epidemiology/etiology/prevention & control Female Humans Postoperative Complications/epidemiology/etiology/prevention & control Prospective Studies Elderly patients General anaesthesia Mean arterial pressure Postoperative delirium
Are Patients Taking Benzodiazepines at Increased Risk for Complications Following Primary Total Knee Arthroplasty?	Hernandez, N. M. Cunningham, D. J. Hinton, Z. W. Wu, C. J. Seyler, T. M.	J Arthroplasty	2021	Arthroplasty, Replacement, Knee/adverse effects Benzodiazepines/adverse effects Humans Joint Diseases Odds Ratio Postoperative Complications/chemically induced/epidemiology Reoperation Retrospective Studies Risk Factors benzodiazepines complications delirium revision total knee arthroplasty
Preoperative medication use and development of postoperative delirium and cognitive dysfunction	Heinrich, M. Nottbrock, A. Borchers, F. Mörgeli, R. Kruppa, J. Winterer, G. Slooter, A. J. C. Spies, C.	Clin Transl Sci	2021
Radiological, Chemical, and Pharmacological Cholinergic System Parameters and Neurocognitive Disorders in Older Presurgical Adults	Heinrich, M. Müller, A. Lammers-Lietz, F. Borchers, F. Mörgeli, R. Kruppa, J. Zacharias, N. Winterer, G. Slooter, A. J. C. Spies, C. D.	J Gerontol A Biol Sci Med Sci	2021	Anticholinergic medication Cholinesterase Cognition Magnetic resonance imaging
Predictors and Sequelae of Postoperative Delirium in a Geriatric Patient Population With Hip Fracture	Haynes, M. S. Alder, K. D. Toombs, C. Amakiri, I. C. Rubin, L. E. Grauer, J. N	J Am Acad Orthop Surg Glob Res Rev	2021	Postoperative Delirium Hip fracture Dementia Geriatric Preoperative dementia
Visual Analytics in Delirium Management	Hackl, W. O. Netzer, M. Nantschev, R. Schaller, M. Ammenwerth, E.	Stud Health Technol Inform	2021	Aged Cluster Analysis Data Mining Delirium Humans Delirium management data visualization patient safety
Characterizing Sleep Disruption and Delirium in Children After Cardiac Surgery: A Feasibility Study	Gregory, J. L. Brown, A. T. Kudchadkar, S. R.	Pediatr Crit Care Med	2021
One-Year Medicare Costs Associated With Delirium in Older Patients Undergoing Major Elective Surgery	Gou, R. Y. Hshieh, T. T. Marcantonio, E. R. Cooper, Z. Jones, R. N. Travison, T. G. Fong, T. G. Abdeen, A. Lange, J. Earp, B. Schmitt, E. M. Leslie, D. L. Inouye, S. K.	JAMA Surg	2021
Implementing Delirium Screening in an Intermediate Care Unit	Gaa, C. A. Akintade, B. F.	J Dr Nurs Pract	2021	confusion assessment method delirium delirium screening intermediate care unit
Malocclusion of Molar Teeth Is Associated with Activities of Daily Living Loss and Delirium in Elderly Critically Ill Older Patients	Fujinami, Y. Hifumi, T. Ono, Y. Saito, M. Okazaki, T. Shinohara, N. Akiyama, K. Kunikata, M. Inoue, S. Kotani, J. Kuroda, Y.	J Clin Med	2021	ICU prognosis frailty poor oral health
Electroencephalography of mechanically ventilated patients at high risk of delirium	Eskioglou, E. Iaquaniello, C. Alvarez, V. Rüegg, S. Schindler, K. Rossetti, A. O. Oddo, M.	Acta Neurol Scand	2021	Eeg critical care delirium
Risk Factors and Antipsychotic Usage Patterns Associated With Terminal Delirium in a Veteran Long-Term Care Hospice Population	Ellsworth, E. M. Bacigalupo, K. J. Palla, K. R. Limaye, S. S. Walkosz, M. J. Szczecinski, S. T. Suda, K. J.	Fed Pract	2021
Does cognitive decline/dementia increase Delirium risk after stroke?	Ding, G. Hua, S. Chen, J. Yang, S. Xie, R.	Psychogeriatrics	2021	Cognitive Dysfunction Delirium Dementia Humans Odds Ratio Stroke cognitive decline meta-analysis stroke.
Heterogeneity in design and analysis of ICU delirium randomized trials: a systematic review	Colantuoni, E. Koneru, M. Akhlaghi, N. Li, X. Hashem, M. D. Dinglas, V. D. Neufeld, K. J. Harhay, M. O. Needham, D. M.	Trials	2021	Adult Critical Illness Delirium/diagnosis/prevention & control Humans Intensive Care Units Randomized Controlled Trials as Topic Critically ill patients Delirium Outcome definition Randomized trials Statistical methods Systematic review
The frequency and quality of delirium documentation in discharge summaries	Chuen, V. L. Chan, A. C. H. Ma, J. Alibhai, S. M. H. Chau, V.	BMC Geriatr	2021	Delirium/diagnosis/epidemiology Documentation Hospitalization Humans Patient Discharge Retrospective Studies Delirium Discharge summary Geriatrics Quality
Using data linkage for national surveillance of clinical quality indicators for dementia care among Australian aged care users	Cations, M. Lang, C. Ward, S. A. Caughey, G. E. Crotty, M. Whitehead, C. Ahern, S. Maddison, J. Inacio, M. C.	Sci Rep	2021
Geriatric fracture centre vs usual care after proximal femur fracture in older patients: what are the benefits? Results of a large international prospective multicentre study	Blauth, M. Joeris, A. Rometsch, E. Espinoza-Rebmann, K. Wattanapanom, P. Jarayabhand, R. Poeze, M. Wong, M. K. Kwek, E. B. K. Hegeman, J. H. Perez-Uribarri, C. Guerado, E. Revak, T. J. Zohner, S. Joseph, D. Gosch, M.	BMJ Open	2021	Aged Aged, 80 and over Cohort Studies Femur Hip Fractures/surgery Humans Prospective Studies Quality of Life geriatric medicine health services administration & management hip orthopaedic & trauma surgery trauma management
Effects of dexmedetomidine on neurocognitive disturbance after elective non-cardiac surgery in senile patients: a systematic review and meta-analysis	Bi, X. Wei, J. Zhang, X.	J Int Med Res	2021	China Cognitive Dysfunction/drug therapy/prevention & control Delirium Dexmedetomidine/therapeutic use Humans Hypotension Postoperative Complications/prevention & control Anesthesiology dexmedetomidine non-cardiac surgery postoperative cognitive disturbance postoperative delirium senile
Non-pharmacological interventions for preventing delirium in hospitalised non-ICU patients (Review)	Burton JK, Craig LE, Yong SQ, Siddiqi N, Teale EA, Woodhouse R, Barugh AJ, Shepherd AM, Brunton A, Freeman SC, Sutton AJ, Quinn TJ	Cochrane Database of Systematic Reviews	2021
Incidence and risk factors for postoperative delirium after liver transplantation: a systematic review and meta-analysis	Zhou, S. Deng, F. Zhang, J. Chen, G.	Eur Rev Med Pharmacol Sci	2021
The perioperative application of continuous cerebral autoregulation monitoring for cerebral protection in elderly patients	Zhang, Y. Tan, J. Li, P. Zhang, X. Yang, Y. Liu, Y. Fu, Q. Cao, J. Mi, W. Zhang, H. Li, H.	Ann Palliat Med	2021	Aged Arterial Pressure Cerebrovascular Circulation Homeostasis Humans Male Middle Aged Oximetry Spectroscopy, Near-Infrared Cerebral autoregulation (CA) optimal mean arterial pressure (optimal MAP) regional cerebral oxygen saturation (rScO2) robotic-assisted laparoscopic radical prostatectomy (RALP)
Prospective Randomized Controlled Pilot Study of High-Intensity Lightbox Phototherapy to Prevent ICU-Acquired Delirium Incidence	Zhang, K. S. Pelleg, T. Hussain, S. Kollipara, V. Loschner, A. Foroozesh, M. B. Rubio, E. Biscardi, F. Ie, S. R.	Cureus	2021	bright light therapy circadian rhythm delirium in icu icu delirium prolonged mechanical ventilation quality improvement and patient safety
Neurocognitive disorders in the elderly: altered functional resting-state hyperconnectivities in postoperative delirium patients	Winterer, J. M. Ofosu, K. Borchers, F. Hadzidiakos, D. Lammers-Lietz, F. Spies, C. Winterer, G. Zacharias, N.	Transl Psychiatry	2021	Aged Delirium Humans Magnetic Resonance Imaging Prefrontal Cortex Prospective Studies Rest
Relationships between preoperative cortical thickness, postoperative electroencephalogram slowing, and postoperative delirium	White, M. F. Tanabe, S. Casey, C. Parker, M. Bo, A. Kunkel, D. Nair, V. Pearce, R. A. Lennertz, R. Prabhakaran, V. Lindroth, H. Sanders, R. D.	Br J Anaesth	2021	cortical slowing cortical thickness delirium neurodegeneration surgery
COVID-19 in adults with dementia: clinical features and risk factors of mortality-a clinical cohort study on 125 patients	Vrillon, A. Mhanna, E. Aveneau, C. Lebozec, M. Grosset, L. Nankam, D. Albuquerque, F. Razou Feroldi, R. Maakaroun, B. Pissareva, I. Cherni Gherissi, D. Azuar, J. François, V. Hourrègue, C. Dumurgier, J. Volpe-Gillot, L. Paquet, C.	Alzheimers Res Ther	2021	Aged, 80 and over COVID-19/complications/ mortality COVID-19 Testing Comorbidity Dementia/complications/virology Female France/epidemiology Humans Male Prospective Studies Risk Factors Covid-19 Dementia Mortality Prognostic factors SARS-CoV-2
Risk Factors for Delirium after Vascular Surgery: A Systematic Review and Meta-Analysis	Visser, L. Prent, A. Banning, L. B. D. van Leeuwen, B. L. Zeebregts, C. J. Pol, R. A.	Ann Vasc Surg	2021
Etiologies of Delirium in Consecutive COVID-19 Inpatients and the Relationship Between Severity of Delirium and COVID-19 in a Prospective Study With Follow-Up	Velásquez-Tirado, J. D. Trzepacz, P. T. Franco, J. G.	J Neuropsychiatry Clin Neurosci	2021	Covid-19 Delirium Psychiatric Status Rating Scales Severity of Illness Index
Increased Emergency Department Hallway Length of Stay is Associated with Development of Delirium	van Loveren, K. Singla, A. Sinvani, L. Calandrella, C. Perera, T. Brave, M. Becker, L. Li, T.	West J Emerg Med	2021	Adolescent Adult Aged Case-Control Studies Causality Delirium/ epidemiology/physiopathology Emergency Service, Hospital/ statistics & numerical data Humans Length of Stay Logistic Models Male Middle Aged Pilot Projects Retrospective Studies Time-to-Treatment
Delirium in Children Undergoing Hematopoietic Cell Transplantation: A Multi-Institutional Point Prevalence Study	Traube, C. Gerber, L. M. Mauer, E. A. Small, K. Broglie, L. Chopra, Y. R. Duncan, C. N. Ebens, C. L. Fitzgerald, J. C. Freedman, J. L. Hudspeth, M. P. Hurley, C. Mahadeo, K. M. McArthur, J. Shapiro, M. C. Sharron, M. P. Wall, D. A. Zinter, M. S. Greenwald	Front Oncol	2021	cancer cornell assessment of pediatric delirium delirium hematopoietic cell transplant incidence pediatric oncology risk factors
Agreement Between the Mini-Cog in the Preoperative Clinic and on the Day of Surgery and Association With Postanesthesia Care Unit Delirium: A Cohort Study of Cognitive Screening in Older Adults	Tiwary, N. Treggiari, M. M. Yanez, N. D. Kirsch, J. R. Tekkali, P. Taylor, C. C. Schenning, K. J.	Anesth Analg	2021	Aged Aged, 80 and over Anesthesia Recovery Period Anesthesia, General/ adverse effects Cognition Cognitive Dysfunction/complications/ diagnosis/psychology Elective Surgical Procedures/ adverse effects Emergence Delirium/diagnosis/ etiology/psychology Female Humans Male Mental Status and Dementia Tests Predictive Value of Tests Preoperative Care Reproducibility of Results Risk Assessment Risk Factors Treatment Outcome
A qualitative analysis of clinicians' communication strategies with family members of patients experiencing hospital-acquired delirium	Taylor, G. B. Radhakrishnan, N. Fisher, C. L. Price, C. Tighe, P. Le, T. Bylund, C. L.	Geriatr Nurs	2021
A scalable approach for developing clinical risk prediction applications in different hospitals	Sun, H. Depraetere, K. Meesseman, L. De Roo, J. Vanbiervliet, M. De Baerdemaeker, J. Muys, H. von Dossow, V. Hulde, N. Szymanowsky, R.	J Biomed Inform	2021	Acute kidney injury Clinical decision support Delirium Electronic health records (EHR) Machine learning Scalability Sepsis
The Relative Impact of Specific Postoperative Complications on Older Patients Undergoing Hip Fracture Repair	Stahl, C. C. Funk, L. M. Schumacher, J. R. Zarzaur, B. L. Scarborough, J. E.	Jt Comm J Qual Patient Saf	2021
Brain MRI after critical care admission: A longitudinal imaging study	Sprung, J. Warner, D. O. Knopman, D. S. Petersen, R. C. Mielke, M. M. Jack, C. R., Jr. Martin, D. P. Hanson, A. C. Schroeder, D. R. Przybelski, S. A. Schulte, P. J. Laporta, M. L. Weingarten, T. N. Vemuri, P.	J Crit Care	2021	AD-signature cortex Corpus callosum Cortical thinning Hippocampus Intensive care unit Magnetic resonance imaging Older adults
Effect of age on dexmedetomidine treatment for ventilated patients with sepsis: a post-hoc analysis of the DESIRE trial	Sato, T. Kawazoe, Y. Miyagawa, N. Yokokawa, Y. Kushimoto, S. Miyamoto, K. Ohta, Y. Morimoto, T. Yamamura, H.	Acute Med Surg	2021	Delirium dexmedetomidine elderly sedative effect sepsis
Effects of comprehensive geriatric care models on postoperative outcomes in geriatric surgical patients: a systematic review and meta-analysis	Saripella, A. Wasef, S. Nagappa, M. Riazi, S. Englesakis, M. Wong, J. Chung, F.	BMC Anesthesiol	2021	Adverse outcomes Comprehensive geriatric assessment Comprehensive geriatric care model Delirium Elderly Surgery Long-Term Care
Influence of Age on Postoperative Neurological Outcomes after Surgery of Acute Type A Aortic Dissection	Salem, M. Salib, M. Friedrich, C. Salem, M. Puehler, T. Schoettler, J. Schoeneich, F. Cremer, J. Haneya, A.	J Clin Med	2021	acute type A aortic dissection moderate hypothermic circulatory arrest neurological complication in elderly after type A aortic dissection
Associations between caregiver-detected delirium and symptoms of depression and anxiety in family caregivers of critically ill patients: a cross-sectional study	Rosgen, B. K. Krewulak, K. D. Davidson, J. E. Ely, E. W. Stelfox, H. T. Fiest, K. M.	BMC Psychiatry	2021	Adult Anxiety/diagnosis Anxiety Disorders Caregivers Critical Illness Cross-Sectional Studies Delirium/diagnosis Depression/diagnosis Humans Anxiety Caregiver Depression Family Intensive care
A Core Outcome Set for Research Evaluating Interventions to Prevent and/or Treat Delirium in Critically Ill Adults: An International Consensus Study (Del-COrS)	Rose, L. Burry, L. Agar, M. Campbell, N. L. Clarke, M. Lee, J. Marshall, J. C. Devlin, J. W. Blackwood, B. Needham, D. M. Siddiqi, N. Page, V.	Crit Care Med	2021
Postoperative delirium is associated with decreased recovery of ambulation one-month after surgery	Robinson, T. N. Kovar, A. Carmichael, H. Overbey, D. M. Goode, C. M. Jones, T. S.	Am J Surg	2021	Aged Delirium/ physiopathology Female Humans Male Middle Aged Mobility Limitation Postoperative Complications/ physiopathology Postoperative Period Recovery of Function Accelerometer activity tracker Ambulation Older adults Postoperative delirium
Emergence delirium in children: a Brazilian survey	Quintão, V. C. Sales, C. K. O. Herrera, E. M. Ellerkmann, R. K. Rosen, H. D. Carmona, M. J. C.	Braz J Anesthesiol	2021	Anesthesia Child Emergence delirium Survey
Perioperative dexmedetomidine administration to prevent delirium in adults after non-cardiac surgery: A systematic review and meta-analysis	Qin, C. Jiang, Y. Lin, C. Li, A. Liu, J.	J Clin Anesth	2021	Adult Aged Bradycardia Delirium/epidemiology/prevention & control Dexmedetomidine Humans Hypotension Postoperative Complications/epidemiology/prevention & control Delirium Intraoperative Meta-analysis
Probable Delirium as a Risk Factor for Adverse Surgical Outcomes in Geriatric Patients With Acute Hip Fracture: Preoperative Assessment Using a Short Screening Tool	Perkins, J. L. Perera, S. Beach, M. Esper, S. A. Gruen, G. S. Neft, M.	AANA J	2021	Adverse outcomes delirium hip fracture preoperative anesthesia
Cognitive Stimulation in an Intensive Care Unit: A Qualitative Evaluation of Barriers to and Facilitators of Implementation	Parker, A. M. Aldabain, L. Akhlaghi, N. Glover, M. Yost, S. Velaetis, M. Lavezza, A. Mantheiy, E. Albert, K. Needham, D. M.	Crit Care Nurse	2021
Does Delirium Phenomenology in Persons with Advanced Cancer Follow a Specific Pattern?	Pallotti, M. C. Lopez-Fidalgo, J. Centeno, C. Celin, D. Biasco, G. Giovannini, M. Maltoni, M. Noguera, A.	J Palliat Med	2021	Mdas cancer delirium phenomenology
Dexmedetomidine, Delirium, and Adverse Outcomes: Analysis of the STS Adult Cardiac Surgery Database	Pal, N. Abernathy, J. H., 3rd Taylor, M. A. Bollen, B. A. Shah, A. S. Feng, X. Shotwell, M. S. Kertai, M. D.	Ann Thorac Surg	2021	cardiac surgery delirium dexmedetomidine mortality postoperative pain
Factors associated with delirium after cardiac surgery: A prospective cohort study	Ordóñez-Velasco, L. M. Hernández-Leiva, E.	Ann Card Anaesth	2021	Body mass index cardiopulmonary bypass cerebral near infrared spectroscopy intensive care unit postoperative delirium
Baseline sleep as a predictor of delirium after surgical aortic valve replacement: A feasibility study	Oldham, M. A. Pigeon, W. R. Chapman, B. Yurcheshen, M. Knight, P. A. Lee, H. B.	Gen Hosp Psychiatry	2021	Apnea/hypopnea index Obstructive sleep apnea Postoperative delirium Sleep efficiency Surgical aortic valve replacement
What Does a Diagnosis of Depression Mean for Patients Undergoing Colorectal Surgery?	Oduyale, O. K. Eltahir, A. A. Stem, M. Prince, E. Zhang, G. Q. Safar, B. Efron, J. E. Atallah, C.	J Surg Res	2021	Colorectal surgery Depression Mortality Postoperative outcomes
A randomized double-blind placebo-controlled trial of intravenous thiamine for prevention of delirium following allogeneic hematopoietic stem cell transplantation	Nakamura, Z. M. Deal, A. M. Park, E. M. Quillen, L. J. Chien, S. A. Stanton, K. E. McCabe, S. D. Heiling, H. M. Wood, W. A. Shea, T. C. Rosenstein, D. L.	J Psychosom Res	2021	Cognitive impairment Delirium Hematopoietic stem cell transplantation Thiamine Wernicke’s encephalopathy Wernicke-Korsakoff syndrome
The 4-DSD: A New Tool to Assess Delirium Superimposed on Moderate to Severe Dementia	Morandi, A. Grossi, E. Lucchi, E. Zambon, A. Faraci, B. Severgnini, J. MacLullich, A. Smith, H. Pandharipande, P. Rizzini, A. Galeazzi, M. Massariello, F. Corradi, S. Raccichini, A. Scrimieri, A. Morichi, V. Gentile, S. Lucchini, F. Pecorella, L. Mossello	J Am Med Dir Assoc	2021	Delirium delirium superimposed on dementia dementia older
Are dexmedetomidine and olanzapine suitable to control delirium in critically ill elderly patients? A retrospective cohort study	Liu, S. Zhao, R. Yang, R. Zhao, H. Ji, C. Duan, M. Liu, J.	Biomed Pharmacother	2021	Critical illness Delirium Dexmedetomidine Drug-related side effects and adverse reactions Intensive care unit Olanzapine
Association between glucose variability and postoperative delirium in acute aortic dissection patients: an observational study	Lin, Y. J. Lin, L. Y. Peng, Y. C. Zhang, H. R. Chen, L. W. Huang, X. Z. Chen, Q.	J Cardiothorac Surg	2021	Acute Disease Adult Aneurysm, Dissecting/blood/ surgery Blood Glucose/ analysis Cardiac Surgical Procedures/adverse effects Cardiovascular Surgical Procedures/ adverse effects Delirium/ blood/diagnosis/etiology Female Humans Intensive Care Units Length of Stay Male Middle Aged Prognosis Proportional Hazards Models Prospective Studies Risk Factors Survival Analysis Acute aortic dissection patient Glucose variability Postoperative delirium
Frailty is associated with a higher risk of developing delirium and cognitive impairment among patients with diabetic kidney disease: A longitudinal population-based cohort study	Lee, S. Y. Wang, J. Chao, C. T. Chien, K. L. Huang, J. W.	Diabet Med	2021	chronic kidney disease cognitive impairment delirium diabetes mellitus diabetic kidney disease frail phenotype
Multi-Component Care Bundle in Geriatric Fracture Hip for Reducing Post-Operative Delirium	Lam, D. M. H. Wang, C. Lee, A. K. H. Chung, Y. F. Lau, T. W. Fang, C. Leung, F. Chan, T. C. W.	Geriatr Orthop Surg Rehabil	2021	delirium fascia iliaca block geriatric fracture hip geriatric trauma multi-component care bundle postoperative delirium ultrasound-guided fascia iliaca block
Occurrence of Delirium during ECMO Therapy in a Critical Care Unit in Poland-A Cross-Sectional Pilot Study	Krupa, S. Friganovic, A. Mędrzycka-Dąbrowska, W.	Int J Environ Res Public Health	2021	Critical Care Cross-Sectional Studies Delirium/epidemiology Extracorporeal Membrane Oxygenation/adverse effects Humans Pilot Projects Poland/epidemiology delirium extracorporeal membrane oxygenation
Steroids to reduce the impact on delirium (STRIDE): a double-blind, randomised, placebo-controlled feasibility trial of pre-operative dexamethasone in people with hip fracture	Kluger, M. T. Skarin, M. Collier, J. Rice, D. A. McNair, P. J. Seow, M. Y. Connolly, M. J.	Anaesthesia	2021	delirium dexamethasone hip fracture prevention
Elevated plasma levels of galectin-3 binding protein are associated with post-stroke delirium - A pilot study	Klimiec-Moskal, E. Pasinska, P. Kowalska, K. Klimkowicz-Mrowiec, A. Pera, J. Slowik, A. Dziedzic, T.	J Neuroimmunol	2021	Delirium Gal-3BP Hmgb1 Inflammation Ischemic stroke
Postoperative delirium after cardiac surgery of elderly patients as an independent risk factor for prolonged length of stay in intensive care unit and in hospital	Kirfel, A. Menzenbach, J. Guttenthaler, V. Feggeler, J. Mayr, A. Coburn, M. Wittmann, M.	Aging Clin Exp Res	2021	Cardiac surgery Diagnosis of delirium Elderly patients Length of stay Postoperative delirium
ED-DEL: Development of a change package and toolkit for delirium in the emergency department	Kennedy, M. Webb, M. Gartaganis, S. Hwang, U. Biese, K. Stuck, A. Lesser, A. Hshieh, T. Inouye, S. K.	J Am Coll Emerg Physicians Open	2021	aging delirium emergency department geriatrics organizational innovation quality assurance quality improvement
Elevated Monocyte Chemoattractant Protein-1 as the Independent Risk Factor of Delirium after Cardiac Surgery. A Prospective Cohort Study	Kaźmierski, J. Miler, P. Pawlak, A. Jerczyńska, H. Woźniak, J. Frankowska, E. Brzezińska, A. Woźniak, K. Krejca, M. Wilczyński, M.	J Clin Med	2021	cardiac surgery coronary artery bypass grafting delirium high-sensitivity C-reactive protein monocyte chemoattractant protein-1
Prevalence of and factors associated with physical restraint use in the intensive care unit: a multicenter prospective observational study in Japan	Kawai, Y. Hamamoto, M. Miura, A. Yamaguchi, M. Masuda, Y. Iwata, M. Kanbe, M. Ikematsu, Y.	Intern Emerg Med	2021	Associated factors Intensive care unit (ICU) Physical restraint Prevalence
Added value of anxiolytic benzodiazepines in predictive models on severe delirium in patients with acute decompensated heart failure: A retrospective analysis	Kawada, K. Fukuda, H. Kubo, T. Ohta, T. Ishida, T. Morisawa, S. Kawazoe, T. Okamoto, M. Fujita, H. Jobu, K. Morita, Y. Ueba, T. Kitaoka, H. Miyamura, M.	PLoS One	2021