What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Effects of gabapentin on slow-wave sleep period in critically ill adult patients: A randomized controlled trial
- Authors
- Susantitapong, K. Dilokpattanamongkol, P. Sutherasan, Y. Liamsombut, S. Suthisisang, C.
- Year
- 2024
- Journal
- Clin Transl Sci
- Abstract
Sleep deprivation is a prevalent problem in critically ill patients, which leads to delayed recovery and delirium. Slow-wave sleep (SWS) is essential to energy restoration, tissue repair, and immune system strengthening. This study aimed to investigate the effects of gabapentin on SWS in critically ill patients. We performed a prospective open-label randomized controlled study to compare SWS and the clinical outcomes of gabapentin versus a control intervention in critically ill adult patients admitted to the intensive care unit (ICU) within 24 h. The patients’ characteristics and sleep-related outcomes were recorded. The sleep-related outcomes, namely, bispectral analysis (BIS), the Richards-Campbell Sleep Questionnaire (RCSQ), and insulin-like growth factor-1 (IGF-1) levels, were evaluated. Furthermore, clinical outcomes and safety were assessed. Sixty patients from 348 cases were eligible for randomization. On day 3 of the study, patients in the gabapentin group had significantly increased SWS (66.79 vs. 0.00 min; p < 0.001), total sleep time (TST) (331.39 vs. 46.16 min; p = 0.001), RCSQ score (55.05 ± 20.18 vs. 32.80 ± 15.31; p < 0.001), and IGF-1 concentrations (84.33 ± 12.40 vs. 44.00 ± 10.20 ng/mL, p < 0.001) compared with the control group. Improvements in clinical outcomes, such as delirium, ICU-free days, and mechanical ventilator-free days, were observed; however, these differences did not reach statistically significant. Gabapentin at bedtime increased SWS, TST, and IGF-1 concentrations in critically ill patients. This regimen might be beneficial to critically ill patients for improving their sleep quality.
- PMID
PMID: 38803031
PMCID: PMC11130453
- Keywords
Humans
*Gabapentin/therapeutic use/administration & dosage
*Critical Illness
Male
Female
Middle Aged
Aged
Prospective Studies
*Sleep, Slow-Wave/drug effects
Adult
Intensive Care Units
Insulin-Like Growth Factor I/metabolism/analysis
Sleep Deprivation/drug therapy/physiopathology
Treatment Outcome
- Page(s)
- Volume
- Issue
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| Effect of Ascorbic Acid on the Incidence of Postoperative Delirium Among Elderly Patients Undergoing Cardiovascular Surgery: A Pilot Study | Iizuka, Y. Fukano, K. Oki, S. Sawada, I. Miyazawa, K. Ono, S. Yoshinaga, K. Sanui, M. Yamaguchi, A. | J Clin Med Res | 2025 |
Ascorbic acid Cardiac surgery Postoperative delirium |
| Preoperative Cognitive Optimization and Postoperative Cognitive Outcomes: A Narrative Review | Ishizawa, Y. | Clin Interv Aging | 2025 |
Humans *Delirium/prevention & control Aged Cognitive Dysfunction/prevention & control Postoperative Cognitive Complications/prevention & control Cognition Preoperative Care/methods Postoperative Complications/prevention & control cognitive frailty cognitive optimization perioperative neurocognitive disorder postoperative cognitive impairment postoperative delirium |
| Delirium risk profiles in a population-based study of United States older adults undergoing common noncardiac surgeries | Joo, H. Avelino-Silva, T. J. Diaz-Ramirez, L. G. Lee, S. J. Whitlock, E. L. | J Am Geriatr Soc | 2025 |
Humans Male Aged Female United States/epidemiology Risk Factors *Delirium/epidemiology Aged, 80 and over *Postoperative Complications/epidemiology Surgical Procedures, Operative/adverse effects Medicare/statistics & numerical data Risk Assessment/methods and noncardiac surgeries older adults postoperative delirium risk profile |
| Risk factors and outcomes of hyperactive delirium in older medical inpatients admitted to non-intensive care unit: a prospective cohort study | Kaewpongsa, P. Jayanama, K. Ruangritchankul, S. | BMC Psychiatry | 2025 |
Humans *Delirium/epidemiology/diagnosis Male Female Risk Factors Aged Prospective Studies Aged, 80 and over *Inpatients/statistics & numerical data Middle Aged Hospitalization *Psychomotor Agitation/epidemiology Hyperactive delirium Mortality Older adults Risk factor |
| A multicenter prospective study on the prevalence of Post Stroke Delirium and associated risk factors in Addis Ababa, Ethiopia | Ketema, B. Mengistu, G. Melka, D. Zenebe, Y. Zebenigus, M. Leul, F. | BMC Neurol | 2025 |
Humans *Delirium/epidemiology/etiology/diagnosis Ethiopia/epidemiology Female Male Risk Factors Prevalence Middle Aged Prospective Studies Aged *Stroke/epidemiology/complications Adult Aged, 80 and over Delirium Stroke Tikur Anbessa Specialized Hospital Yehulshet Specialty Center Yekatit 12 Hospital and Medical College |
| Clinical Profile and Outcome of Delirium in Patients in The Semi-Closed Intensive Care Unit | Keyal, N. K. Sherpa, A. D. Kumar, R. Ansari, I. | J Nepal Health Res Counc | 2025 |
Humans *Delirium/epidemiology Male *Intensive Care Units Female Prospective Studies Middle Aged Nepal/epidemiology Adult *apache Risk Factors Aged Length of Stay/statistics & numerical data Respiration, Artificial Delirium intensive care units mortality. |
| SURGE-ahead postoperative delirium prediction: external validation and open-source library | Kocar, T. D. Wolf, P. Leinert, C. Brefka, S. Fotteler, M. L. Uihlein, A. Wezel, F. Wehling, M. Rahbari, N. Kestler, H. Gebhard, F. Dallmeier, D. Denkinger, M. | Eur Geriatr Med | 2025 |
Artificial intelligence Delirium prediction Explainable AI Machine learning Postoperative delirium |
| The Impact of Non-Pharmacological Sleep Interventions on Delirium Prevention and Sleep Improvement in Postoperative ICU Patients: A Systematic Review and Network Meta-Analysis | Li, J. Fan, Y. Luo, R. Yin, N. Wang, Y. Jing, J. Zhang, J. | Intensive Crit Care Nurs | 2025 |
Humans *Delirium/prevention & control *Intensive Care Units/organization & administration *Network Meta-Analysis as Topic Delirium Intensive Care Unit Network meta-analysis Non-pharmacological interventions Sleep |
| Developing a nomogram for postoperative delirium in elderly patients with hip fractures | Li, L. Sheng, W. W. Song, L. J. Cheng, S. Cui, E. G. Zhang, Y. B. Yu, X. Z. Liu, Y. L. | World J Psychiatry | 2025 |
Hip fracture Nomogram Postoperative delirium Retrospective study Risk factor |
| The effect of perioperative cognitive training on postoperative delirium in older patients undergoing total hip and knee arthroplasty: a prospective randomised trial | Lia, T. Yua, C. Lv, F. Feng, Z. Hou, Y. Ren, L. Li, P. | Age Ageing | 2025 |
Humans Aged *Arthroplasty, Replacement, Knee/adverse effects *Arthroplasty, Replacement, Hip/adverse effects Male Female Prospective Studies Middle Aged Delirium/prevention & control/epidemiology/diagnosis/psychology/etiology Incidence Cognitive Behavioral Therapy/methods Postoperative Complications/prevention & control/epidemiology/etiology Cognition Treatment Outcome Perioperative Care/methods Cognitive Training general anaesthesia older people postoperative delirium total hip and knee arthroplasty |
| Delirium is a Potential Predictor of Unfavorable Long-term Functional Outcomes in Patients with Acute Ischemic Stroke: A Prospective Observational Study | Lin, C. Zhang, H. Xiao, F. Tu, Y. Lin, Y. Zhan, L. Lin, Y. Li, Y. Xie, C. Chen, Y. | J Inflamm Res | 2025 |
Ais Psd acute ischemic stroke biomarkers coagulation dysfunction delirium mRS modified rankin scale neuroinflammation post-stroke delirium |
| Evidence from a Mendelian randomization study: Delirium's noncausal role in dementia onset | Lu, Z. Wang, X. Mao, T. Liu, L. Zhang, J. | Neuroscience | 2025 |
Delirium Dementia Mendelian randomization Older people |
| Evaluation of postoperative delirium in cardiac surgery patients with the SDACS screening tool: a multicenter-multiphase study | Mahmoudi, H. Chalkias, A. Moradi, A. Moradian, S. T. Amouzegar, S. M. R. Vahedian-Azimi, A. | Perioper Med (Lond) | 2025 |
Cardiac surgery Critical care Delirium Early prediction Intensive care Screening tool |
| Nurse-perceived barriers and facilitators influencing optimal delirium care in acute care patients: Findings from the INVOLVE_RN study on barriers and facilitators | Mailhot, T. Crump, L. Clausen, C. Valentine-Joannette, T. Bouaouina, Z. Leblanc, M. E. Bitzas, V. Khetir, I. Lavoie, P. | Geriatr Nurs | 2025 |
Acute care Barriers Delirium Facilitators Guidelines Nursing practice |
| Delirium in the Acute Care Setting From the Families Perspective: A Scoping Review | McLean, A. Ewens, B. Towell-Barnard, A. | J Adv Nurs | 2025 |
acute care delirium families experience family centred care nursing |
| Establishment and validation of a nomogram of postoperative delirium in patients undergoing cardiac surgery: a retrospective study of MIMIC-IV | Mei, H. Liao, G. Ye, B. Wen, M. Li, J. | BMC Cardiovasc Disord | 2025 |
Humans *Nomograms Male Female Retrospective Studies *Cardiac Surgical Procedures/adverse effects Aged Middle Aged Risk Assessment Risk Factors *Predictive Value of Tests Reproducibility of Results *Decision Support Techniques Databases, Factual Delirium/diagnosis/etiology/epidemiology Treatment Outcome Cardiac surgery Icu Mimic-iv Nomogram Postoperative delirium |
| Cytokines and inflammatory biomarkers and their association with post-operative delirium: a meta-analysis and systematic review | Mosharaf, M. P. Alam, K. Gow, J. Mahumud, R. A. | Sci Rep | 2025 |
Humans *Biomarkers/blood *Cytokines/blood *Delirium/blood/etiology/diagnosis *Postoperative Complications/blood/etiology Inflammation/blood/metabolism C-reactive proteins Cytokines and inflammatory proteins Interleukins Post-operative delirium Systematic review and meta-analysis |
| Preoperative brain volume loss is associated with postoperative delirium in advanced heart failure patients supported by left ventricular assist device | Murrieta-Álvarez, I. Scioscia, J. P. Benítez-Salazar, J. M. Uwaeze, J. Xu, Z. Zheng, G. Li, S. Braverman, V. Walther, C. P. Shafii, A. E. Hochman-Mendez, C. Rosengart, T. K. Liao, K. K. Mondal, N. K. | Sci Rep | 2025 |
Humans *Heart-Assist Devices/adverse effects *Heart Failure *Delirium/etiology Male Female Middle Aged *Brain/diagnostic imaging/pathology Aged *Postoperative Complications/etiology Tomography, X-Ray Computed Atrophy Preoperative Period Retrospective Studies Brain Delirium Heart failure Mechanical circulatory support Neuroimaging Neurological dysfunction |
| Assessing delirium knowledge among health care professionals: findings from a scoping review | Muzzana, C. Mansutti, I. Palese, A. Ausserhofer, D. | BMC Nurs | 2025 |
Delirium Health personnel Healthcare professionals Instruments Knowledge Scoping review |
| Delirium assessment, management and barriers to effective care across Scotland: A secondary analysis of survey data from World Delirium Awareness Day 2023 | Naeem, F. Penfold, R. S. Soiza, R. L. Von Haken, R. Lindroth, H. Liu, K. Nydhal, P. Quinn, T. J. | J R Coll Physicians Edinb | 2025 |
*Delirium/therapy/diagnosis Humans Scotland Guideline Adherence/statistics & numerical data Surveys and Questionnaires Aged Prevalence Practice Guidelines as Topic Male Scotland/epidemiology delirium geriatrics hospitals |
| Screening of toxic-metabolic encephalopathy with and without epileptic seizure with density spectral array | Ohno, N. Neshige, S. Abe, T. Nonaka, M. Yamada, H. Takebayashi, Y. Ishibashi, H. Shishido, T. Aoki, S. Yamazaki, Y. Ueno, H. Iida, K. Maruyama, H. | J Neurol Sci | 2025 |
Loss of consciousness Neurotoxicity Nonconvulsive seizure Seizure Status epilepticus |
| Development and Validation of a Machine Learning Model for Early Prediction of Delirium in Intensive Care Units Using Continuous Physiological Data: Retrospective Study | Park, C. Han, C. Jang, S. K. Kim, H. Kim, S. Kang, B. H. Jung, K. Yoon, D. | J Med Internet Res | 2025 |
Humans *Delirium/diagnosis *Machine Learning *Intensive Care Units Male Retrospective Studies Female Middle Aged Aged Reproducibility of Results Adult delirium early prediction intensive care unit machine learning prediction model |
| Persistence of Delirium in Postacute Care at Skilled Nursing Facilities | Park, C. M. Shi, S. Jones, R. N. Metzger, E. D. Vasunilashorn, S. M. Fong, T. Kim, D. H. Inouye, S. K. | JAMA Netw Open | 2025 |
Humans *Skilled Nursing Facilities/statistics & numerical data *Delirium/epidemiology/diagnosis Female Male Cross-Sectional Studies *Subacute Care/statistics & numerical data Aged United States/epidemiology Aged, 80 and over *Medicare/statistics & numerical data |
| Delirium on presentation with a hip fracture is associated with adverse outcomes : a multicentre observational study of 18,040 patients using national clinical registry data | Penfold, R. S. Farrow, L. Hall, A. J. Clement, N. D. Ward, K. Donaldson, L. Johansen, A. Duckworth, A. D. Anand, A. Hall, D. E. Guthrie, B. MacLullich, A. M. J. | Bone Joint J | 2025 |
Humans *Delirium/epidemiology/etiology *Hip Fractures/complications/surgery Female Male *Registries Aged, 80 and over Aged Scotland/epidemiology Middle Aged Prevalence Hospital Mortality Risk Factors |
| Association between hyperlipidemia and postoperative delirium risk: a systematic review and meta-analysis | Qiu, L. Q. Song, J. L. Zhang, L. C. Fan, B. Li, Q. Lu, B. Chen, G. Y. | Front Aging Neurosci | 2025 |
hypercholesterolemia hyperlipidemias hypertriglyceridemia meta-analysis postoperative delirium |
| Postoperative Delirium after Reverse Total Shoulder Arthroplasty: Interscalene Block Versus General Anesthesia | Rhee, S. M. Kim, S. Y. Kim, C. H. Radhakrishna, K. Dwivedi, D. D. Kim, S. Y. Ham, H. J. Rhee, Y. G. | Clin Orthop Surg | 2025 |
Humans Aged *Anesthesia, General *Arthroplasty, Replacement, Shoulder/adverse effects Aged, 80 and over Male Female Prospective Studies Case-Control Studies *Rotator Cuff Injuries/surgery Delirium/etiology Postoperative Complications/etiology Nerve Block Interscalene nerve block Postoperative delirium Total shoulder arthroplasty |
| Prevalence and Risk Factors for Delirium on Arrival at the Emergency Room by Ambulance | Sakuramoto, H. Onuma, J. Uno, S. Ikeda, M. Okamoto, S. Nakano, H. Hasimoto, H. Ouchi, A. | Cureus | 2025 |
ambulance delirium emergency room older adults psychiatry |
| Validation and Translation of the 3D-CAM to Turkish in Surgical Intensive Care Patients | Sarı, S. Dilsiz, P. Eker, T. Şahin, S. Şahin, M. D. Doğan, B. Özçiftçi, P. Özcan, H. Dostbil, A. İyisoy, M. S. Turan, O. Taşkın, F. Kyenshilik, D. Kazaylek, M. İnce, İ Turan, A. | Turk J Anaesthesiol Reanim | 2025 |
3d-cam Delirium Intensive Care Turkish Version Validation |
| Evaluating oxygen reserve index-guided oxygenation for the prevention of postoperative delirium in elderly patients: a randomized controlled trial | Sarıtaş, P. U. Sarıtaş, A. Poyraz, MÇ | Croat Med J | 2025 |
Humans Aged Female Male *Oximetry *Postoperative Complications/prevention & control Delirium/prevention & control/etiology Aged, 80 and over Oxygen/blood Incidence Oxygen Inhalation Therapy/methods Oxygen Saturation |
| Delirium prevalence and management in general wards, emergency departments, rehabilitation centres and nursing homes in Germany, Austria and Switzerland (DACH countries): A secondary analysis of a worldwide point prevalence study | Schimböck, F. Krüger, L. Hoffmann, M. Jeitziner, M. M. Lindroth, H. Liu, K. Nydahl, P. Von Haken, R. Thomas Exl, M. Fischbacher, S. | Int J Nurs Stud Adv | 2025 |
Delirium Encephalopathy Nurses Prevalence Protocol |
| Lipid Dysregulation and Delirium in Older Adults: A Review of the Current Evidence and Future Directions | Shaw, A. Teng, R. Fasina, T. Gonzales, A. S. Wong, A. Schweitzer, D. Akefe, I. | Brain Res Bull | 2025 |
Delirium Endocannabinoids Fatty Acids Healthy Ageing Lipid Dysregulation Neuropsychiatric Disorders Phospholipids Sphingolipids |
| Risk factors for transitions and outcomes of subsyndromal delirium in the ICU: Post-hoc analysis of a prospective multicenter cohort study | Smit, L. Wiegers, E. J. A. Trogrlic, Z. Gommers, D. Ista, E. van der Jagt, M. | J Crit Care | 2025 |
Critical care Delirium Diagnosis Intensive care unit Outcomes Risk factors |
| Protein Alterations in Patients with Delirium after Cardiac Surgery: An Exploratory Case-Control Substudy of the VISION Cardiac Surgery Biobank | Spence, J. Devereaux, P. J. Bashir, S. Brady, K. Sun, T. Chan, M. T. V. Wang, C. Y. Lamy, A. Whitlock, R. P. McIntyre, W. F. Belley-Côté, E. Paré, G. Chong, M. | Anesthesiology | 2025 |
Humans Male Female *Cardiac Surgical Procedures/adverse effects Case-Control Studies *Delirium/blood/etiology/diagnosis Aged *Biomarkers/blood *Postoperative Complications/blood/diagnosis/etiology *Biological Specimen Banks Middle Aged Blood Proteins/analysis Cohort Studies |
| Association Between Oxidative Stress Markers and Postoperative Delirium in Elderly Patients Undergoing Oncologic Surgery | Stanculescu, A. D. Dragoescu, P. O. Andrei, M. Chiutu, L. Dragoescu, N. A. | Curr Health Sci J | 2024 |
Postoperative delirium glutathione peroxidase malondialdehyde superoxide dismutase |
| Long-term mortality impact of postoperative hyperactive delirium in older hip fracture surgery patients | Sun, M. Chen, W. M. Wu, S. Y. Zhang, J. | BMC Geriatr | 2025 |
Humans Female *Hip Fractures/surgery/mortality Male Aged Aged, 80 and over *Postoperative Complications/mortality/epidemiology/diagnosis *Delirium/mortality/epidemiology/diagnosis Taiwan/epidemiology Risk Factors Cohort Studies Propensity Score Hip fracture Mortality Older Postoperative hyperactive delirium Propensity score matching |
| Person-centered care-based digital transformation education program for elderly dementia patients with delirium: a comparison of the effect on nurses and doctors | Suzuki, M. Ito, T. Inagaki, K. Mimuro, S. Yamakawa, M. Takiue, K. Sawaki, K. Komatsu, Y. Uchiyama, M. Kawashima, C. Yamazaki, K. Satoh, M. Isogai, S. | Nihon Ronen Igakkai Zasshi | 2025 |
Humans *Dementia/nursing/therapy *Patient-Centered Care *Delirium/therapy/nursing Aged *Nurses Female *Physicians Male Surveys and Questionnaires Delirium Dementia Digital transformation (DX) program Person-centered care |
| Risk factors for postoperative delirium in patients undergoing orthopedic procedures: a systematic review and meta-analysis | Suzuki, R. Nakanishi, A. Masuya, M. Fukuroku, K. Taneda, Y. Matsuura, Y. | PLoS One | 2025 |
Humans Risk Factors *Orthopedic Procedures/adverse effects *Delirium/etiology/epidemiology *Postoperative Complications/etiology/epidemiology Length of Stay |
| Airway Safety During Mechanical Ventilation: Survey of ICU Clinicians Practices and Perceptions | Tanios, M. A. Stocking, J. C. Charchaflieh, J. G. Miller, A. G. Patel, J. V. Vilella, A. L. Nguyen, H. M. Epstein, S. K. Beltran, A. Devlin, J. W. | Crit Care Explor | 2025 |
Humans *Intensive Care Units *Respiration, Artificial/adverse effects Surveys and Questionnaires Airway Management/methods/adverse effects Patient Safety Airway Extubation/adverse effects Attitude of Health Personnel Practice Patterns, Physicians’/statistics & numerical data |
| A Cross-Sectional Study of Online Survey Respondents' Knowledge and Attitudes Toward Delirium | Townshend, R. Vasilevskis, E. E. Hollnagel, F. Golden, B. P. | J Gen Intern Med | 2025 |
caregiver education delirium patient education |
| Impact of Ketamine and Propofol on Cognitive Function in Elderly Patients: A Systematic Review | Van de Vel, G. Mun, S. Zia, S. U. D. Chalasani, R. Shukla, P. S. Malasevskaia, I. | Cureus | 2025 |
delirium elderly ketamine postoperative cognitive dysfunction propofol |
| Preoperative quantitative quadriceps muscle ultrasound to predict POD for gastrointestinal surgery in older patients | Wang, C. Song, X. Cao, L. Guo, F. Gao, J. | BMC Gastroenterol | 2025 |
Humans Male Female Aged *Ultrasonography/methods *Quadriceps Muscle/diagnostic imaging *Postoperative Complications/etiology/diagnostic imaging *Digestive System Surgical Procedures/adverse effects/methods Risk Factors Prospective Studies *Delirium/etiology Preoperative Period Aged, 80 and over Nomograms ROC Curve China Logistic Models Predictive Value of Tests Gastrointestinal surgery Nomogram Postoperative delirium Quantitative muscle ultrasound |
| Medical staff's knowledge of delirium by occupation and the effectiveness of an on-demand e-learning | Yamagata, H. Kobayashi, R. Hirose, K. Seki, T. Takihara, T. | PCN Rep | 2025 |
delirium e‐learning liaison psychiatry staff education team‐based medicine |
| The relationship between preoperative serum indirect bilirubin and postoperative delirium in geriatric patients undergoing joint replacement | Yu, R. Yang, M. Chen, J. Zhang, F. | PLoS One | 2025 |
Humans Male Female Aged *Bilirubin/blood Aged, 80 and over *Arthroplasty, Replacement, Knee/adverse effects *Delirium/blood/etiology/diagnosis *Postoperative Complications/blood/etiology Arthroplasty, Replacement, Hip/adverse effects Risk Factors Preoperative Period |
| Exploring the causal relationship between delirium and sarcopenia using bidirectional two-sample Mendelian randomization study | Zhou, R. Fu, Y. Wan, P. Cheng, B. | Prog Neuropsychopharmacol Biol Psychiatry | 2025 |
Appendicular lean mass Delirium Gwas Low hand-grip strength Mendelian randomization |
| Preventive effects of early mobilisation on delirium incidence in critically ill patients: systematic review and meta-analysis | Zhou, L. Xie, F. Zeng, Y. Xia, X. Wang, R. Cai, Y. Lei, Y. Xu, F. Li, X. Chen, B. | Med Klin Intensivmed Notfmed | 2025 |
Delirium Early mobilisation Intervention Non-drug intervention Rehabilitation |
| Comparison of the effects of perioperative fentanyl and morphine use on the short-term prognosis of patients with cardiac surgery in the ICU | Zhong, J. Sui, R. Zi, J. Wang, A. | Front Pharmacol | 2024 |
cardiac surgery delirium fentanyl in-hospital mortality morphine |
| Comparison of the effects of perioperative fentanyl and morphine use on the short-term prognosis of patients with cardiac surgery in the ICU | Zhong, J. Sui, R. Zi, J. Wang, A. | Front Pharmacol | 2024 |
cardiac surgery delirium fentanyl in-hospital mortality morphine |
| Comparison of the effects of perioperative fentanyl and morphine use on the short-term prognosis of patients with cardiac surgery in the ICU | Zhong, J. Sui, R. Zi, J. Wang, A. | Front Pharmacol | 2024 |
cardiac surgery delirium fentanyl in-hospital mortality morphine |
| Development and usability evaluation of a nurse-led clinical decision support system (AI-AntiDelirium) for management of intensive care unit delirium: A mixed methods study | Zhang, S. Ding, S. Cui, W. Li, X. Wei, J. Wu, Y. | Appl Nurs Res | 2025 |
Humans *Delirium/nursing Cross-Sectional Studies *Decision Support Systems, Clinical Female Male Adult *Intensive Care Units Middle Aged Critical Care Nursing/methods/standards Nursing Staff, Hospital/psychology Clinical decision supporting system Delirium Intensive care unit Nurses Usability testing |
| Serum-derived exosomal microRNAs as biomarkers for postoperative delirium | Xu, M. Chen, Y. Lin, Y. Wang, D. Zheng, X. | Front Neurosci | 2025 |
biomarkers cognitive decline microRNA postoperative delirium serum exosomes |
| Enhanced machine learning predictive modeling for delirium in elderly ICU patients with COPD and respiratory failure: A retrospective study based on MIMIC-IV | Wu, Z. B. Jiang, Y. L. Li, S. S. Li, A. | PLoS One | 2025 |
Humans *Delirium/diagnosis *Machine Learning Aged Female Male *Pulmonary Disease, Chronic Obstructive/complications *Intensive Care Units *Respiratory Insufficiency Retrospective Studies Aged, 80 and over Risk Factors Prognosis |
| Unraveling the impact of frailty on postoperative delirium in elderly surgical patients: a systematic review and meta-analysis | Wu, H. Yan, S. Cao, H. Feng, C. Zhang, H. | BMC Anesthesiol | 2025 |
Humans *Frailty Aged Postoperative Complications/epidemiology Frail Elderly Delirium/epidemiology Emergence Delirium/epidemiology Delirium Elderly Frailty Meta-analysis |
| Evaluating the relationship between inflammatory markers and preoperative delirium in elderly hip fracture patients: A retrospective observational study | Wang, S. Yu, S. Li, C. Li, T. Li, H. Zhang, B. Han, L. Zhan, H. Zhang, Y. | Medicine (Baltimore) | 2025 |
Humans *Hip Fractures/surgery/blood/complications *Delirium/blood/etiology/diagnosis/epidemiology Male Retrospective Studies Female Aged Aged, 80 and over *Biomarkers/blood Inflammation/blood Preoperative Period Risk Factors Age Factors Neutrophils/metabolism Comorbidity |
| Predictors of postoperative delirium in patients undergoing radical prostatectomy: a prospective study | Wang, H. Chen, J. Chen, J. Chen, Y. Qin, Y. Liu, T. Pan, S. Xie, Y. | Support Care Cancer | 2025 |
Humans Male Prospective Studies *Prostatectomy/adverse effects/methods Aged Risk Factors *Postoperative Complications/epidemiology/etiology *Delirium/etiology/epidemiology Middle Aged *Nomograms Prostatic Neoplasms/surgery Logistic Models Elderly patients Nomogram Postoperative delirium Prostate cancer |
| Development of a Disease Model for Predicting Postoperative Delirium Using Combined Blood Biomarkers | Wan, H. Tian, H. Wu, C. Zhao, Y. Zhang, D. Zheng, Y. Li, Y. Duan, X. | Ann Clin Transl Neurol | 2025 |
blood biomarkers cognitive decline hyperlipidemia machine learning postoperative delirium |
| Consequences of the Crisis in Social Care for Older Hospital Inpatients with Frailty | Ahmed, R. Cloonan, J. May, E. Chambers, H. Madden, R. Doyle, J. Briggs, R. | Ir Med J | 2025 |
Humans Female Male Aged Aged, 80 and over *Frail Elderly *Quality of Life Patient Discharge Inpatients/psychology Home Care Services Depression/epidemiology Frailty Accidental Falls/statistics & numerical data/prevention & control Delirium/therapy/epidemiology Loneliness/psychology Hospitalization/statistics & numerical data |
| Predicting Postoperative Delirium Using Intraoperative Neuromonitoring in Patients Undergoing Craniotomy for Aneurysm Clipping Surgery | Al-Qudah, A. M. Alkalbani, L. Tallapaneni, P. S. Vinuthna, D. V. Suresh, V. Anetakis, K. M. Crammond, D. Balzer, J. Shandal, V. Visweswaran, S. Subramaniam, K. Sadhasivam, S. Thirumala, P. | Eur Neurol | 2025 |
Postoperative delirium, Intracranial surgery, IONM, SSEPs, EEG, CBF |
| Intraoperative neuromonitoring as an independent predictor for postoperative delirium in ICU following aneurysm clipping | Al-Qudah, A. M. Tallapaneni, P. S. Crammond, D. J. Balzer, J. Anetakis, K. M. Shandal, V. Biaesch, J. Ghannam, M. Nadkarni, N. Gross, B. A. Lang, M. Subramanium, K. Sadhasivam, S. Thirumala, P. D. | eNeurologicalSci | 2025 |
Aneurysm Clipping Craniotomy Delirium Icu Intraoperative neurophysiologic monitoring SSEP EEG |
| Daylighting and Patients' Access to View Assessment in the Palestinian Hospitals' ICUs | Amleh, D. Halawani, A. Haj Hussein, M. Alamlih, L. | Herd | 2025 |
Icu access to view daylight delirium human health |
| Virtual Reality Simulation to Improve Postoperative Cardiothoracic Surgical Patient Outcomes | Anderson, R. J. Bauer, P. R. Arghami, A. Haney, R. M. Reisdorf, E. M. Baalson, K. | Am J Crit Care | 2025 |
Humans *Virtual Reality Male Female Middle Aged Aged *Intensive Care Units Cardiac Surgical Procedures Postoperative Complications/prevention & control Respiration, Artificial |
| Association of Number of Oral bacteria with Ventilator-Associated Pneumonia and Delirium in Patients in the Intensive Care Unit | Arimizu, C. Akahoshi, T. Jinno, T. Furuta, M. Ohashi, A. Takamori, S. Wada, N. | J Intensive Care Med | 2025 |
delirium intensive care unit oral bacterial count oral care ventilator-associated pneumonia |
| Impact of a Collaborative Pharmacist-Cardiovascular Surgeon Protocol for High Risk of Postoperative Delirium on Benzodiazepine Prescription Trends in Hospitalized Patients | Asai, Y. Nakano, Y. Yanagawa, T. Takahashi, M. Iwamoto, T. | Biol Pharm Bull | 2025 |
Humans *Benzodiazepines/therapeutic use/adverse effects Retrospective Studies *Pharmacists *Delirium/drug therapy/epidemiology/prevention & control Male Female Aged *Postoperative Complications/prevention & control/epidemiology Middle Aged Surgeons Drug Prescriptions/statistics & numerical data Practice Patterns, Physicians’/trends/statistics & numerical data Cardiovascular Surgical Procedures/adverse effects Hospitalization/trends Aged, 80 and over Interrupted Time Series Analysis benzodiazepine insomnia drug interrupted time series prescription trend protocol-based pharmacotherapy management |
| Supportive Interventions Involving Family Carers of Patients With Delirium Superimposed on Dementia in Hospital: A Scoping Review | Ashton-Gough, C. Lynch, J. Goodman, C. | Int J Older People Nurs | 2025 |
Humans *Delirium/nursing *Dementia/nursing/complications *Caregivers/psychology Hospitalization Aged Family/psychology carers delirium dementia family caregiving non‐pharmacological interventions |
| The Misdiagnosis and Underdiagnosis of Hepatic Encephalopathy | Bloom, P. P. | Clin Transl Gastroenterol | 2025 |
*Hepatic Encephalopathy/diagnosis/etiology Humans *Diagnostic Errors *Liver Cirrhosis/complications/diagnosis *Cognitive Dysfunction/diagnosis/etiology Diagnosis, Differential Delirium/diagnosis/etiology Dementia/diagnosis Risk Factors |
| Delirium in Neurocritical Care: Uncovering Undisclosed Psychotropic Substance and Medication Use and Stress Exposure by Hair Analysis | Bögli, S. Y. Capone, C. Baumgartner, M. R. Quednow, B. B. Kraemer, T. Keller, E. Binz, T. M. | Neurocrit Care | 2025 |
Humans Male Female Middle Aged Aged *Delirium/metabolism/etiology/drug therapy *Psychotropic Drugs Adult *Critical Care *Hair Analysis Stress, Psychological/metabolism Hair/chemistry/metabolism Endocannabinoids/metabolism Brain Injuries/metabolism/complications Acute brain injury Delirium Hair analysis Neurocritical care |
| Sublingual sufentanil after orthopaedic and abdominal surgery: long-term outcome and safety | Borck, M. Wandrey, J. D. Spies, C. Tafelski, S. | Perioper Med (Lond) | 2025 |
Patient-controlled analgesia Postoperative chronic pain Postoperative delirium Postoperative pain management Sublingual sufentanil tablet system |
| A single-center prospective cohort study assessing preoperative gait speed assessment as a prognostic tool for morbidity and mortality in frail elderly patients undergoing abdominal surgery | Cai, P. P. Gu, L. L. Wang, X. Wu, C. L. Ye, X. H. Zhang, K. Z. | Braz J Med Biol Res | 2025 |
Humans Prospective Studies Aged Female Male *Frail Elderly *Walking Speed/physiology *Postoperative Complications/mortality Prognosis Aged, 80 and over Risk Factors *Geriatric Assessment/methods Abdomen/surgery Risk Assessment/methods Predictive Value of Tests Preoperative Period |
| Construction of a risk prediction model to identify potential risk factors for the development of delirium after total hip arthroplasty | Cheng, Y. C. | Medicine (Baltimore) | 2024 |
Humans *Arthroplasty, Replacement, Hip/adverse effects Male Female *Delirium/etiology/epidemiology Risk Factors Retrospective Studies Middle Aged *Postoperative Complications/epidemiology/etiology Aged Risk Assessment/methods Logistic Models Femoral Neck Fractures/surgery |
| A pilot trial exploring the use of music in the emergency department and its association with delirium and other clinical outcomes | Ní Chróinín D Wang, S. Nagaraj, G. Ren, S. Middleton, P. M. Short, A. | Emerg Med Australas | 2025 |
Humans *Delirium/prevention & control Female Male Pilot Projects Aged *Emergency Service, Hospital/statistics & numerical data Prospective Studies *Music Therapy/methods Aged, 80 and over Feasibility Studies delirium emergency service hospital music patient outcome assessment |
| The Prevention and Treatment of Postoperative Delirium in the Elderly: A Narrative Systematic Review of Reviews | Deblois, S. Bergeron, N. Vu, T. T. M. Paquin-Lanthier, G. Nauche, B. Pomp, A. | J Patient Saf | 2025 |
Postoperative delirium, literature review, hip fracture patients, preventative measures, delirium management |
| The effect of music interventions compared to standard-of-care on the prevention of delirium in neurosurgical patients: an analysis of costs and cost-effectiveness based on the MUSYC-trial | Dirven, T. L. A. Kappen, P. R. van der Beek, F. T. H. van der Holt, B. Jeekel, H. Dirven, C. M. F. Vincent, Ajpe Klimek, M. Poley, M. J. | Acta Neurochir (Wien) | 2025 |
Humans *Cost-Benefit Analysis *Music Therapy/methods/economics Male Female Middle Aged *Delirium/prevention & control/economics *Postoperative Complications/prevention & control/economics Aged *Neurosurgical Procedures/economics/adverse effects Standard of Care Craniotomy/adverse effects/economics Adult Quality of Life Treatment Outcome Cost Delirium Efficiency Music Neurosurgery |
| Effect of oxygen delivery during cardiopulmonary bypass on postoperative neurological outcomes in patients undergoing cardiac surgery: A scoping review of the literature | Elsebaie, A. Shakeel, A. Zhang, S. Alarie, M. El Tahan, M. El-Diasty, M. | Perfusion | 2025 |
Humans *Cardiopulmonary Bypass/methods/adverse effects *Cardiac Surgical Procedures/adverse effects/methods *Oxygen/blood Postoperative Complications/etiology/prevention & control Nervous System Diseases/etiology/prevention & control cardiac surgery cardiopulmonary bypass cognitive dysfunction delirium oxygen delivery postoperative neurological complications stroke |
| Anesthesia-induced electroencephalogram oscillations and perioperative outcomes in older adults undergoing cardiac surgery | Freedman, I. G. Boncompte, G. Qu, J. Z. Khawaja, Z. Q. Turco, I. Mueller, A. Wiredu, K. McKay, T. B. Westover, M. B. Pedemonte, J. C. Akeju, O. | J Clin Anesth | 2025 |
Humans Female Aged Male *Anesthesia, General/adverse effects *Electroencephalography/drug effects *Cardiac Surgical Procedures/adverse effects Middle Aged *Dexmedetomidine/adverse effects/administration & dosage Emergence Delirium/epidemiology/diagnosis/prevention & control Patient Readmission/statistics & numerical data Postoperative Complications/epidemiology/etiology/diagnosis Isoflurane/adverse effects/administration & dosage Anesthetics, Inhalation/adverse effects/administration & dosage Cardiopulmonary Bypass/adverse effects Aged, 80 and over Incidence Elective cardiac surgery Intraoperative alpha power Intraoperative electroencephalogram Perioperative outcomes Postoperative delirium |
| Prevention and management of postoperative delirium in adult patients: a best practice implementation project | Gnatta, J. R. Paes, S. O. G. Faria, M. F. O. Cicarelli, D. D. Laurino, R. V. S. Hamano, L. Püschel, V. A. A. Poveda, V. B. | Rev Esc Enferm USP | 2025 |
Humans *Postoperative Complications/prevention & control *Delirium/prevention & control Practice Guidelines as Topic Adult Guideline Adherence Evidence-Based Practice |
| Prediction model for delirium in advanced cancer patients receiving palliative care: development and validation | Guo, D. Zhang, C. Leng, C. Fan, Y. Wang, Y. Chen, L. Zhang, H. Ge, N. Yue, J. | BMC Palliat Care | 2025 |
Humans *Delirium/etiology *Palliative Care/methods/standards Female Male Middle Aged *Neoplasms/complications Prospective Studies Aged China/epidemiology Nomograms Logistic Models Aged, 80 and over Adult Risk Factors ROC Curve Delirium Neoplasms Nomogram Palliative care |
| Videodistraction to reduce agitation in elderly patients in the emergency department: an open label parallel group randomized controlled trial | Güvec, E. Koedel, U. Horster, S. Pedersen, V. Völk, S. Waldow, M. Weber, F. Klein, M. | Eur J Emerg Med | 2025 |
Humans *Psychomotor Agitation *Emergency Service, Hospital Aged Male Female Prospective Studies Aged, 80 and over Delirium/prevention & control/diagnosis Video Recording Geriatric Assessment/methods |
| Comprehensive Geriatric Assessment, Treatment Decisions, and Outcomes in Older Patients Eligible for Pancreatic Surgery | Hartog, M. Beishuizen, S. J. E. Togo, R. van Bruchem-Visser, R. L. van Eijck, C. H. J. Mattace-Raso, F. U. S. Pek, C. J. de Wilde, R. F. Groot Koerkamp, B. Polinder-Bos, H. A. | J Surg Oncol | 2024 |
Humans Aged Male Female *Pancreatic Neoplasms/surgery/mortality/pathology Prospective Studies *Geriatric Assessment Aged, 80 and over *Postoperative Complications/epidemiology Frailty/complications Pancreatectomy/mortality Pancreaticoduodenectomy/adverse effects/mortality Frail Elderly Clinical Decision-Making Follow-Up Studies Prognosis Survival Rate elderly frailty functional decline geriatric oncology pancreatic cancer pancreatic surgery periampullary cancer |
| Pharmacological Strategies for Providing Patients With Delirium Relief From Terminal Dyspnea: A Secondary Data Analysis | Hasegawa, T. Mori, M. Yamaguchi, T. Imai, K. Matsuda, Y. Maeda, I. Hatano, Y. Yokomichi, N. Hamano, J. Morita, T. | Cancer Med | 2025 |
Humans *Delirium/drug therapy *Dyspnea/drug therapy/etiology Male Female Aged *Antipsychotic Agents/therapeutic use *Analgesics, Opioid/therapeutic use *Palliative Care/methods Middle Aged Prospective Studies Aged, 80 and over Neoplasms/complications/drug therapy Japan Terminal Care/methods Treatment Outcome Secondary Data Analysis antipsychotic agents delirium dyspnea neoplasm opioid palliative care |
| Associations of Frailty Status and Sleep Quality With Incident Delirium: A Prospective Study in the UK Biobank | Huang, Y. Chen, G. Ma, N. Wang, L. Wang, Y. Jia, Z. Huang, M. He, D. | CNS Neurosci Ther | 2025 |
Humans Female Male *Delirium/epidemiology United Kingdom/epidemiology *Frailty/epidemiology/complications Aged *Sleep Quality Middle Aged Prospective Studies *Biological Specimen Banks Incidence Risk Factors Sleep Wake Disorders/epidemiology Aged, 80 and over Follow-Up Studies Adult UK Biobank delirium incidence frailty interaction prospective study sleep quality |
| Intra- and early postoperative predictors of delirium risk in cardiac surgery: results from the prospective observational FINDERI study | Itting, P. T. Sadlonova, M. Santander, M. J. Knierim, M. Derad, C. Asendorf, T. Celano, C. M. Hansen, N. Esselmann, H. Heinemann, S. Eberhard, C. Hoteit, M. Schröder, M. F. Kutschka, I. Wiltfang, J. von Arnim, C. A. F. Baraki, H. | Int J Surg | 2025 |
Postoperative delirium, cardiac surgery, early postoperative factors, CAM, machine learning |
| Inpatient Use of Valproic Acid in Agitated Delirium by Palliative Medicine | Jacobs, S. Herbst, L. Fernandez, C. Mehta, Z. Y. Young, A. Davis, M. P. | Am J Hosp Palliat Care | 2025 |
agitated delirium antipsychotic and benzodiazepine sparing therapy delirium hospital care valproate valproic acid |
| Preventative interventions for postoperative delirium after intraabdominal surgery - A systematic review and meta-analysis of randomized trials | Jensen, J. Thorhauge, K. Petri, C. L. Madsen, M. T. Burcharth, J. | Am J Surg | 2025 |
Intra-abdominal Meta-analysis Postoperative delirium Preventive interventions Surgery Systematic review |
| Patients' and family members' dyadic experience of post-operative delirium in the intensive care unit: A qualitative study | Jing, D. Weijing, S. Yiyu, Z. | Nurs Crit Care | 2025 |
Humans *Qualitative Research Male Female *Intensive Care Units *Family/psychology *Delirium/psychology *Postoperative Complications/psychology Middle Aged Aged Interviews as Topic Adult critical care patient‐ and family‐centred care post‐operative delirium qualitative research |
| Use of Oral Celecoxib Preoperatively Reduces Risk of Delirium and Favors Functional Recovery in Elderly Patients with Femoral Neck Fracture: A Propensity Score-Matched Analysis | Ju, M. Han, X. He, L. Jiang, J. Wang, M. Lin, W. Liu, Y. | J Pain Res | 2025 |
celecoxib delirium elderly femoral neck fracture pain |
| Perioperative Near Infrared Spectroscopy Measurements of Cerebral Regional Oxygen Desaturations Are Not Associated With Delirium After Cardiac Surgery | Kahn, R. A. Egorova, N. Ouyang, Y. Huang, J. Levin, M. A. Hofer, I. Anyanwu, A. Weiner, M. M. | J Cardiothorac Vasc Anesth | 2025 |
cardiac surgery delirium near-infrared spectroscopy postoperative outcome regional cerebral oximetry |
| Melatonin for preventing postoperative delirium in elderly patients: A multicenter randomized placebo-controlled pilot study | Khaled, M. Chui, J. Ewusie, J. Agzarian, J. Bogach, J. Gomez, M. Shayegan, B. Shargall, Y. Alkhamesi, N. Paul, J. Thabane, L. Shanthanna, H. | Medicine (Baltimore) | 2025 |
Humans *Melatonin/therapeutic use/administration & dosage Aged Male Female Pilot Projects *Postoperative Complications/prevention & control/epidemiology *Delirium/prevention & control/epidemiology/etiology Feasibility Studies Aged, 80 and over Incidence Double-Blind Method Sleep Quality Medication Adherence |
| The Effects of Remimazolam and Inhalational Anesthetics on the Incidence of Postoperative Hyperactive Delirium in Geriatric Patients Undergoing Hip or Femur Surgery Under General Anesthesia: A Retrospective Observational Study | Kim, J. Lee, S. Yoo, B. H. Lim, Y. H. Jun, I. J. | Medicina (Kaunas) | 2025 |
Humans Male Female Aged Retrospective Studies Incidence *Anesthetics, Inhalation/adverse effects *Benzodiazepines/therapeutic use/adverse effects Aged, 80 and over *Anesthesia, General/adverse effects *Postoperative Complications/epidemiology Femur/surgery Delirium/epidemiology Sevoflurane/adverse effects Hip/surgery Emergence Delirium/epidemiology Propensity Score Logistic Models hip surgery postoperative delirium remimazolam sevoflurane |
| The Role of Cytokines in Perioperative Neurocognitive Disorders: A Review in the Context of Anesthetic Care | Koh, H. J. Joo, J. | Biomedicines | 2025 |
anesthesia blood–brain barrier cytokine neuroinflammation perioperative neurocognitive disorder postoperative cognitive dysfunction postoperative delirium |
| Evaluation of the Quality of Delirium Website Content for Patient and Family Education: Cross-Sectional Study | Krewulak, K. Strayer, K. Jaworska, N. Spence, K. Foster, N. Kupsch, S. Sauro, K. Fiest, K. M. | J Med Internet Res | 2025 |
Humans *Delirium *Internet Cross-Sectional Studies *Family Patient Education as Topic/standards/methods accessibility brain lesions caregiver confusion delirium disorientation education family education health information high-quality websites inattentiveness information seeking internet patient readability |
| Subcutaneous dexmedetomidine for sedation of agitated delirium in palliative care | Lapenskie, J. Downar, J. Wolfe, A. Polskaia, N. van den Berg, K. Watt, C. Bush, S. H. Boese, K. Barnes, C. J. Parsons, H. A. Kanji, S. Heidinger, B. Lawlor, P. G. | Ann Palliat Med | 2025 |
Humans *Dexmedetomidine/administration & dosage/therapeutic use *Delirium/drug therapy Female Male *Palliative Care/methods Prospective Studies Aged *Hypnotics and Sedatives/therapeutic use/administration & dosage Middle Aged Aged, 80 and over *Psychomotor Agitation/drug therapy Adult Infusions, Subcutaneous Delirium dexmedetomidine palliative care prospective study sedation |
| Association of polypharmacy and perioperative outcomes: Systematic review and meta-analysis | Lee, Y. Liew, Y. Sim, M. H. Sim, X. L. J. | J Perioper Pract | 2025 |
Perioperative outcomes Polypharmacy Postoperative delirium Systematic review |
| Pilot implementation of an electronic diagnostic support tool (AiD-DST) designed to identify the cause(s) of delirium | Leong, E. Chang, S. Yearwood, K. Eeles, E. Yerkovich, S. Ling, C. Teodorczuk, A. Dissanayaka, N. | Australas J Ageing | 2025 |
Humans *Delirium/diagnosis Pilot Projects *Predictive Value of Tests Female Male Decision Support Systems, Clinical Decision Support Techniques Diagnosis, Computer-Assisted Aged delirium digital technology point‐of‐care diagnostics |
| Effect of preoperative oral carbohydrate on postoperative delirium in elderly patients undergoing lower extremity orthopedic surgery: a prospective randomized trial | Li, L. T. Wang, X. H. Zuo, Y. B. He, Y. H. Lin, J. Chen, H. X. Huang, Y. | J Orthop Surg Res | 2025 |
Humans Male Aged Female *Orthopedic Procedures/adverse effects Prospective Studies *Preoperative Care/methods *Postoperative Complications/prevention & control/etiology *Lower Extremity/surgery Incidence Dietary Carbohydrates/administration & dosage C-Reactive Protein/metabolism/analysis Delirium/prevention & control/etiology/epidemiology Blood Glucose/metabolism Interleukin-6/blood Aged, 80 and over Administration, Oral Middle Aged Carbohydrate Older patients Orthopedic surgery Postoperative delirium |
| The triglyceride glucose index and delirium risk in sepsis patients: A causal inference study | Li, X. Yang, J. Tang, Y. Liang, X. Bai, Z. Cheng, H. Wang, Y. Lyu, J. | Nurs Crit Care | 2025 |
Humans *Sepsis/blood *Delirium/epidemiology/blood/etiology/diagnosis Male Female *Triglycerides/blood Middle Aged *Intensive Care Units/statistics & numerical data *Blood Glucose/analysis Risk Factors Aged Incidence Propensity Score causal inference delirium intensive care unit sepsis triglyceride glucose index |
| Intra-operative blood transfusions raise the risk of postoperative delirium and impede functional recovery in elderly hip fracture patients: a propensity score-matched study | Li, Y. Wang, T. Zhang, J. Wang, Z. Guo, J. Zhang, Q. | J Orthop Traumatol | 2025 |
Humans *Hip Fractures/surgery *Propensity Score Female Male Aged Retrospective Studies Aged, 80 and over *Postoperative Complications/epidemiology *Delirium/etiology/epidemiology *Recovery of Function *Length of Stay/statistics & numerical data *Fracture Fixation, Intramedullary/adverse effects/methods Blood Transfusion/statistics & numerical data Risk Factors Incidence Intraoperative Care/methods Blood transfusion Elderly Intertrochanteric fractures Postoperative delirium Postoperative outcome Propensity score matching Retrospective study |
| Geriatric traumatology-Principles of orthogeriatrics | Liener, U. C. Neuerburg, C. Hoffmann, R. Bökeler, U. | Chirurgie (Heidelb) | 2025 |
Humans Aged *Geriatrics *Osteoporotic Fractures/surgery/therapy *Traumatology Aged, 80 and over Female Intersectoral Collaboration Germany Male Complications Delirium Fragility fractures Multimorbidity Osteoporosis |
| Evaluating Midazolam's Influence on Bispectral Index and Propofol Concentrations Using Schnider and Eleveld Models in Target-Controlled Infusion General Anesthesia: A Prospective Observational Study | Linassi, F. Zanatta, P. Kreuzer, M. Ciavattini, E. Rizzetto, C. Carron, M. | Life (Basel) | 2025 |
adverse effects anxiolytics bispectral index monitor elderly infusion pump intravenous anesthesia midazolam propofol |
| Clinical biomarkers of perioperative neurocognitive disorder: initiation and recommendation | Liu, J. Li, C. Yao, J. Zhang, L. Zhao, X. Lv, X. Liu, Z. Miao, C. Wang, Y. Jiang, H. Yu, W. Wang, T. Wang, D. Wang, E. Gu, X. Dong, H. Cao, J. Shen, Y. Song, W. Chen, S. Wang, Y. Liu, G. Xie, Z. Xiong, L. Zheng, J. C. | Sci China Life Sci | 2025 |
biomaker clinical biomarkers perioperative neurocognitive disorders postoperative cognitive dysfunction postoperative delirium |
| Characteristics and risk factors of delirium in patients on veno-arterial extracorporeal membrane oxygenation | Liu, O. Sun, P. Y. Ahmad, S. A. Kalra, A. Feng, A. Whitman, G. J. R. Kim, B. S. Cho, S. M. | Perfusion | 2025 |
delirium veno-arterial ECMO |
| The effect of delirium on the association between frailty and postoperative major complications in elderly patients: a mediation analysis | Liu, Y. F. Cui, F. Su, X. Li, Y. W. Zhang, Y. Li, C. J. Mu, D. L. Wang, D. X. | J Anesth | 2025 |
Elder patients Frailty Mediation analysis Postoperative complications Postoperative delirium |