Delirium Bibliography

Delirium Bibliography books graphicWhat is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!

How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.

Reference Information

Title
Cerebral monitoring of anaesthesia on reducing cognitive dysfunction and postoperative delirium: a systematic review.
Authors
Luo, C. Zou, W.
Year
2018
Journal
J Int Med Res
Abstract

Objective To assess the efficacy of cerebrally monitoring the depth of anaesthesia in reducing postoperative cognitive dysfunction and postoperative delirium (POD). Methods MEDLINE, EMBASE, and Cochrane Library databases were searched following PRISMA statement guidelines. We included randomized clinical trials (RCTs) comparing electroencephalogram-based and routine care-guided titration of anaesthesia in a systematic review. The risk estimate from each RCT was pooled in a meta-analysis. The primary outcome was POD and long-term cognitive dysfunction. Subgroup analyses were conducted for the subtypes of intervention group and surgery. We identified five RCTs with a total sample size of 2,868 and with bispectral index (BIS) or auditory evoked potential (AEP) as interventions. Results The odds ratio (OR) for POD and long-term cognitive decline was 0.51 (95%CI: 0.35-0.76) and 0.69 (95%CI: 0.49-0.97), respectively. Significant heterogeneity was identified in the POD data. There was no significant difference between BIS- and AEP-based titration of anaesthesia in reducing the risk of POD. Extensive heterogeneity for cardiac and thoracic surgery was identified in the study population, and significant publication bias was found among the POD results. Conclusions BIS- and AEP-guided anaesthesia are associated with significantly reduced risk of POD and long-term cognitive dysfunction.

PMID

30014748

Keywords

Anesthesia/*adverse effects/methods
Cognitive Dysfunction/etiology/*prevention & control
Delirium/etiology/*prevention & control
Electroencephalography
Humans
*Intraoperative Neurophysiological Monitoring/methods
Postoperative Complications/etiology/prevention & control
Randomized Controlled Trials as Topic
Cerebral monitoring
anaesthesia
cognitive dysfunction
meta-analysis
postoperative delirium
systematic review

Page(s)
Oct-00
Issue
10

Search:
Total Records Found: 6289, showing 100 per page
TitleAuthorsJournalYearKeywords
The economic cost of delirium: A systematic review and quality assessment Kinchin, I. Mitchell, E. Agar, M. Trépel, D. Alzheimers Dement 2021

Cost-Benefit Analysis/*economics
Delirium/*therapy
Humans
*Quality Assurance, Health Care
*cost
*cost of illness
*delirium
*economic impact
*methodology
*quality assessment
*systematic review

The Risk of Preoperative Central Nervous System-Acting Medications on Delirium Following Hip or Knee Surgery: A Matched Case-Control Study Kassie, G. M. Roughead, E. E. Nguyen, T. A. Pratt, N. L. Kalisch Ellett, L. M. Drug Saf 2021

Preoperative

Central Nervous System

Delirium

Hip or Knee Surgery

Matched Case-Control Study

Association between ankle brachial index and development of postoperative intensive care unit delirium in patients with peripheral arterial disease Kang, J. An, J. H. Jeon, H. J. Park, Y. J. Sci Rep 2021

Aged
Ankle Brachial Index/*methods
Delirium/*complications
Female
Humans
*Intensive Care Units
Leg/blood supply
Male
Peripheral Arterial Disease/physiopathology/*surgery
*Postoperative Care
*Postoperative Complications
Retrospective Studies

Incidence and predictors of delirium on the intensive care unit in patients with acute kidney injury, insight from a retrospective registry Jäckel, M. Aicher, N. Rilinger, J. Bemtgen, X. Widmeier, E. Wengenmayer, T. Duerschmied, D. Biever, P. M. Stachon, P. Bode, C. Staudacher, D. L. Sci Rep 2021

Acute Kidney Injury/*diagnosis/epidemiology
Aged
Aged, 80 and over
Delirium/*diagnosis/epidemiology
Female
Germany/epidemiology
Hospital Mortality
Humans
Incidence
Intensive Care Units/*statistics & numerical data
Length of Stay
Male
Middle Aged
Prognosis
Registries/*statistics & numerical data
Respiration, Artificial
Retrospective Studies
Risk Factors

Advantages of score-based delirium detection compared to a clinical delirium assessment-a retrospective, monocentric cohort study Jäckel, M. Aicher, N. Bemtgen, X. Rilinger, J. Zotzmann, V. Biever, P. M. Supady, A. Stachon, P. Duerschmied, D. Wengenmayer, T. Bode, C. Staudacher, D. L. PLoS One 2021

score-based delirium detection

clinical delirium

monocentric cohort study

A Comparison of Dexmedetomidine and Propofol on Emergence Delirium in Children Undergoing Cleft Palate Surgery With Sevoflurane-Based Anesthesia Huang, L. Wang, L. Peng, W. Qin, C. J Craniofac Surg 2021

Emergence Delirium

Children

Cleft Palate Surgery

Sevoflurane

Automated machine learning-based model predicts postoperative delirium using readily extractable perioperative collected electronic data Hu, X. Y. Liu, H. Zhao, X. Sun, X. Zhou, J. Gao, X. Guan, H. L. Zhou, Y. Zhao, Q. Han, Y. Cao, J. L. CNS Neurosci Ther 2021

delirium
machine learning
model prediction
nomogram
postoperative

Feasibility of low-dose dexmedetomidine for prevention of postoperative delirium after intracranial operations: a pilot randomized controlled trial He, X. Cheng, K. M. Duan, Y. Q. Xu, S. S. Gao, H. R. Miao, M. Y. Li, H. L. Chen, K. Yang, Y. L. Zhang, L. Gu, H. Q. Zhou, J. X. BMC Neurol 2021

Delirium
Dexmedetomidine
Intracranial operation
Postoperative
Prevention

Reliability and validity of the Japanese version of the 4A's Test for delirium screening in the elderly patient Hasegawa, T. Seo, T. Kubota, Y. Sudo, T. Yokota, K. Miyazaki, N. Muranaka, A. Hirano, S. Yamauchi, A. Nagashima, K. Iyo, M. Sakai, I. Asian J Psychiatr 2021

Attention
Delirium
Reliability and validity
Screening tool
World backwards

Neural autoantibodies in delirium Hansen, N. Krasiuk, I. Titsch, T. J Autoimmun 2021

Cognitive dysfunction
Delirium
Neural autoantibody
Postoperative delirium

Risk Factors for Delirium in the Palliative Care Population: A Systematic Review and Meta-Analysis Guo, D. Lin, T. Deng, C. Zheng, Y. Gao, L. Yue, J. Front Psychiatry 2021

delirium
meta-analysis
palliative care
risk factors
systematic revie

Incidence, risk factors, and consequences of emergence delirium after elective brain tumor resection Gu, W. J. Zhou, J. X. Ji, R. Q. Zhou, L. Y. Wang, C. M. Surgeon 2021

Emergence delirium
Neurosurgery
Outcomes
Risk factors

A scientometric study of publications on delirium from 2001 to 2020 Grover, S. Gupta, B. M Asian J Psychiatr 2021

Aged
*Bibliometrics
Databases, Factual
*Delirium
Humans
Ireland
Publications
United States
Bibliometrics
Delirium
Scientometrics

The neuropsychological profile of delirium vulnerability: A systematic review and meta-analysis Ghezzi, E. S. Ross, T. J. Sharman, R. Davis, D. Boord, M. S. Thanabalan, T. Thomas, J. Keage, H. A. D. Neurosci Biobehav Rev 2021

ageing
attention
brain
cognition
cognitive domains
delirium
intra-subject variability
meta-analysis
neuropsychology
risk prediction
systematic review

Cognitive Functionality of Patients with Delirium after Stroke Dostović, Z. Ibrahimagić, OĆ Smajlović, D. Kunić, S. Čustović, A. Psychiatr Danub 2021

Cognition
*Delirium/epidemiology
Humans
Neuropsychological Tests
Prospective Studies
*Stroke/complications

Sleep quality and emergence delirium in children undergoing strabismus surgery: a comparison between preschool- and school-age patients Do, W. Kim, H. S. Kim, S. H. Kang, H. Lee, D. Baik, J. Lee, H. J. Hong, J. M. BMC Anesthesiol 2021

*Emergence delirium
*Pediatrics
*Preoperative sleep quality
*Strabismus surgery

Multicomponent nursing program to prevent delirium in critically ill patients: a randomized clinical trial Contreras, C. C. T. Esteban, A. N. P. Parra, M. D. Romero, M. K. R. Silva, C. G. D. Buitrago, N. P. D. Rev Gaucha Enferm 2021

*Critical Illness
*Delirium/prevention & control
Humans
Incidence
Intensive Care Units

Longitudinal validation of an electronic health record delirium prediction model applied at admission in COVID-19 patients Castro, V. M. Hart, K. L. Sacks, C. A. Murphy, S. N. Perlis, R. H. McCoy, T. H., Jr. Gen Hosp Psychiatry 2021

Covid-19
Delirium
Electronic health records
Machine learning
Predictive modeling
Replication

Independent, Differential Effects of Delirium on Disability and Mortality Risk After Hip Fracture Cartei, A. Mossello, E. Ceccofiglio, A. Rubbieri, G. Polidori, G. Ranalli, C. Cammilli, A. Curcio, M. Cavallini, M. C. Mannarino, G. M. Ungar, A. Toccafondi, G. Peris, A. Marchionni, N. Rostagno, C. J Am Med Dir Assoc 2021

Delirium
functional status
hip fracture
mortality
multidisciplinary

Melatonin and melatonin-receptor agonists to prevent delirium in hospitalized older adults: An umbrella review Blodgett, T. J. Blodgett, N. P. Geriatr Nurs 2021

Circadian Rhythm
Delirium
Melatonin
Older Adults
Ramelteon
Umbrella Review

Barriers to completing the 4AT for delirium and its clinical implementation in two hospitals: a mixed-methods study Alhaidari, A. A. O. Matsis, K. P. Eur Geriatr Med 2021

Delirium
Guideline adherence
Hospitals
Implementation science
New Zealand

The relationship between sensory stimuli and the physical environment in complex healthcare settings: A systematic literature review Bayramzadeh, S. Ahmadpour, S. Aghaei, P. Intensive Crit Care Nurs 2021

*Communication
*Delivery of Health Care
Humans
Noise/adverse effects
Critical care
Healthcare environment design
Intensive care unit
Operating room
Sensory stimuli
Trauma room

Simultaneous bilateral total knee arthroplasty is safe and effective for patients in different ages Ariga, A. Kohno, Y. Nakagawa, Y. Watanabe, T. Katagiri, H. Ohara, T. Shioda, M. Ozeki, N. Amemiya, M. Okawa, A. Sekiya, I. Koga, H. J Orthop Sci 2021

Age groups
Clinical outcomes
Complications
Simultaneous bilateral total knee arthroplasty (SB-TKA)

Machine Learning Algorithm Using Electronic Chart-Derived Data to Predict Delirium After Elderly Hip Fracture Surgeries: A Retrospective Case-Control Study Zhao, H. You, J. Peng, Y. Feng, Y. Front Surg 2021

delirium
elderly
hip fracture
machine learning
surgery

The Effect of Data Length on the Assessment of Dynamic Cerebral Autoregulation with Transfer Function Analysis in Neurological ICU Patients Zhang, W. Lu, H. Zhang, P. Mo, X. Ou, A. Liu, J. Zhong, J. Neurocrit Care 2021

Data length
Dynamic cerebral autoregulation
Invasive arterial blood pressure
Neurological intensive care unit
Transfer function analysis

Clinical Features and Outcomes of Neuropsychiatric Systemic Lupus Erythematosus in China Zhang, S. Li, M. Zhang, L. Wang, Z. Wang, Q. You, H. Wang, Y. Li, M. Zeng, X. J Immunol Res 2021

Adult
Biomarkers
China/epidemiology
Female
Humans
Kaplan-Meier Estimate
Lupus Vasculitis, Central Nervous System/*diagnosis/*epidemiology
Magnetic Resonance Imaging/methods
Male
Neuroimaging/methods
Patient Outcome Assessment
*Phenotype
Prognosis
Proportional Hazards Models
Public Health Surveillance
Severity of Illness Index
Symptom Assessment
Young Adult

Noncontact Monitoring of Heart Rate and Heart Rate Variability in Geriatric Patients Using Photoplethysmography Imaging Yu, X. Laurentius, T. Bollheimer, C. Leonhardt, S. Antink, C. H. IEEE J Biomed Health Inform 2021

Aged
Algorithms
Artifacts
Heart Rate
Humans
*Photoplethysmography
*Signal Processing, Computer-Assisted

Non-Contact Measurement of Heart Rate Variability in Frail Geriatric Patients: Response to Early Geriatric Rehabilitation and Comparison with Healthy Old Community-Dwelling Individuals - A Pilot Study Yu, X. Hoog Antink, C. Leonhardt, S. Bollheimer, L. C. Laurentius, T. Gerontology 2021

Frailty
Geriatric patients
Heart rate variability
Non-contact monitoring
Photoplethysmography imaging

Aggressive patient behaviours and unplanned nursing staff leave - is there an association? Yu, J. J. Holbeach, E. Int J Ment Health Nurs 2021

Aggression
Australia
*Burnout, Professional
Humans
*Nursing Staff
*Psychiatric Nursing
delirium
dementia
geriatric psychiatry
neurobehavioural manifestations
nursing
occupational stress
psychiatric nursing

The Significant Prognostic Factors in Prolonged Intensive/High Care Unit Stay After Living Donor Liver Transplantation Yoshiya, S. Harada, N. Tomiyama, T. Takeishi, K. Toshima, T. Iguchi, T. Itoh, S. Ninomiya, M. Yoshizumi, T. Mori, M. Transplant Proc 2021

Adult
Aged
End Stage Liver Disease/mortality/*surgery
Female
Graft Survival
Hospital Mortality
Hospitalization
Humans
Intensive Care Units
Liver Function Tests
Liver Transplantation/*mortality
Living Donors
Male
Middle Aged
Multivariate Analysis
Prognosis

Mode displaying mouse cursors for reducing input language mode confusion: Utility and user attitude evaluation Yoo, T. Lee, H. Hyun, S. Park, W. Appl Ergon 2021

Confusion
Humans
*Language
*User-Computer Interface
Input language mode confusion
Mode displaying mouse cursor
Multi-language typing

Incidence and influencing factors of post-intensive care cognitive impairment Yao, L. Li, Y. Yin, R. Yang, L. Ding, N. Li, B. Shen, X. Zhang, Z. Intensive Crit Care Nurs 2021

Apache
*Cognitive Dysfunction/epidemiology/etiology
Critical Care
Humans
Incidence
*Intensive Care Units
Prospective Studies
Risk Factors
Cognitive impairment
Critical illness
Influencing factors
Post-intensive care syndrome

Validation of the Simplified Palliative Prognostic Index to Predict Survival for Advanced Cancer Patients in Home Hospice Setting Yang, H. J. Yoon, S. J. Kim, J. S. Kim, S. S. Jung, J. G. Suh, W. Y. Lee, S. Kim, H. G. Lee, Y. W. Korean J Fam Med 2021

Hospice Care
Palliative Care
Prognosis
Survival
reported.

Oral corticosteroid dosage and clinical presentation of psychiatric conditions after steroid use: A consultation-liaison psychiatry service's experience Yagi, Y. Takahashi, Y. Ogata, Y. Yamana, H. Kumakura, Y. Ichihashi, K. Kasai, K. Kondo, S. Neuropsychopharmacol Rep 2021

consultation-liaison psychiatry
corticosteroid
delirium
steroid psychosis
steroid-induced psychiatric disorder

Machine learning-assisted screening for cognitive impairment in the emergency department Yadgir, S. R. Engstrom, C. Jacobsohn, G. C. Green, R. K. Jones, C. M. C. Cushman, J. T. Caprio, T. V. Kind, A. J. H. Lohmeier, M. Shah, M. N. Patterson, B. W. J Am Geriatr Soc 2021

cognitive impairment
delirium
dementia
emergency medicine
machine learning

Effects of perioperative rosuvastatin on postoperative delirium in elderly patients: A randomized, double-blind, and placebo-controlled trial Xu, X. Q. Luo, J. Z. Li, X. Y. Tang, H. Q. Lu, W. H. World J Clin Cases 2021

Elderly
General anesthesia
Perioperative rosuvastatin
Postoperative delirium
Randomised controlled trial

Is Perioperative Dexmedetomidine Associated With a Reduced Risk of Perioperative Neurocognitive Disorders Following Cardiac Surgery? A Systematic Review and Meta-Analysis With Trial Sequential Analysis of Randomized Controlled Trials Xiong, X. Chen, D. Shi, J. Front Med (Lausanne) 2021

cardiac surgery
cognitive dysfunction
delirium
dexmedetomidine
meta-analysis

The effect of pre-operative methylprednisolone on postoperative delirium in elderly patients undergoing gastrointestinal surgery: a randomized, double-blind, placebo-controlled trial Xiang, X. B. Chen, H. Wu, Y. L. Wang, K. Yue, X. Cheng, X. Q. J Gerontol A Biol Sci Med Sci 2021

Delirium
brain-derived neurotrophic factor
heparan sulfate
methylprednisolone
syndecan-1
tumor necrosis factor-α

Social Determinants of Health and Delirium Occurrence and Duration in Critically Ill Adults Wu, T. T. Zegers, M. Kooken, R. Griffith, J. L. Molnar, B. E. Devlin, J. W. van den Boogaard, M. Crit Care Explor 2021

delirium
intensive care
social determinants of health
socioeconomic factors
interest.

Implementation of a Frailty Assessment and Targeted Care Interventions and Its Association with Reduced Postoperative Complications in Elderly Surgical Patients Wilson, S. Sutherland, E. Razak, A. O'Brien, M. Ding, C. Nguyen, T. Rosenkranz, P. Sanchez, S. E. J Am Coll Surg 2021

Frailty, Postoperative outcomes, Geriatrics, Frailty assessment

Prevalence of Mimics and Severe Comorbidity in Patients with Clinically Suspected Transient Global Amnesia Werner, R. Woehrle, J. C. Cerebrovasc Dis 2021

Adult
Aged
Aged, 80 and over
Amnesia, Transient Global/diagnosis/*epidemiology/psychology/therapy
Comorbidity
Diagnosis, Differential
Female
Germany/epidemiology
Humans
Male
Memory, Short-Term
Middle Aged
Neuroimaging
Neurologic Examination
Predictive Value of Tests
Prevalence
Prognosis
Risk Assessment
Risk Factors
Stroke/diagnosis/*epidemiology/psychology/therapy
Time Factors
*Clinical neurology
*Emergency neurology
*Transient global amnesia

The risk of delirium and falls or fractures with the use of overactive bladder anticholinergic medications Welk, B. Etaby, K. McArthur, E. Chou, Q. Neurourol Urodyn 2021

anticholinergics
delirium
elderly
falls
overactive bladder

Hospitalization Outcomes of Delirium in Patients Admitted to Acute Care Hospitals in Their Last Year of Life: A Population-Based Retrospective Cohort Study Webber, C. Watt, C. L. Bush, S. H. Lawlor, P. G. Talarico, R. Tanuseputro, P. J Pain Symptom Manage 2021

Adult
*Aftercare
Cohort Studies
*Delirium/diagnosis/epidemiology/therapy
Hospitalization
Hospitals
Humans
Ontario/epidemiology
Patient Discharge
Retrospective Studies
*Delirium
*end-of-life
*hospitalizations
*lengths of stay
*patient discharge

Anticholinergics and clinical outcomes amongst people with pre-existing dementia: A systematic review Wang, K. Alan, J. Page, A. T. Dimopoulos, E. Etherton-Beer, C. Maturitas 2021

Anticholinergic
Cognitive impairment
Dementia
Medications
Medicines
Older adults
Older people
Quality use of medicines

Association Between Intraoperative Arterial Hypotension and Postoperative Delirium After Noncardiac Surgery: A Retrospective Multicenter Cohort Study Wachtendorf, L. J. Azimaraghi, O. Santer, P. Linhardt, F. C. Blank, M. Suleiman, A. Ahn, C. Low, Y. H. Teja, B. Kendale, S. M. Schaefer, M. S. Houle, T. T. Pollard, R. J. Subramaniam, B. Eikermann, M. Wongtangman, K. Anesth Analg 2021

Intraoperative Arterial Hypotension, Postoperative delirium, Surgery, Anesthesia

Dynamic assessments of hepatic encephalopathy and ammonia levels predict mortality in acute-on-chronic liver failure Verma, N. Dhiman, R. K. Choudhury, A. Taneja, S. Duseja, A. Singh, V. Al Mahtab, M. Devarbhavi, H. Shukla, A. Ning, Q. Hamid, S. S. Butt, A. S. Jafri, W. Tan, S. S. Hu, J. Zhongping, D. Treeprasertsuk, S. Lee, G. H. Ghazinyan, H. Lesmana, L. A. Sood, A. M Hepatol Int 2021

*Acute-On-Chronic Liver Failure
Ammonia
*Hepatic Encephalopathy
Humans
Liver Cirrhosis
Prognosis
Severity of Illness Index
Aclf
Altered sensorium
Cirrhosis
Delirium
Hepatic coma
Liver failure
Natural history
Outcomes
Predictive models
Survival

Evaluation of the impact of cataract surgery on cognitive function in very elderly patients: a prospective, observational study Verdina, T. Stiro, F. Bruni, F. Spedicato, G. A. Mastropasqua, R. Cavallini, G. M. Aging Clin Exp Res 2021

6-item cognitive impairment test (6CIT)
Cataract surgery
Cognitive function
Mild cognitive impairment (MCI)
Postoperative delirium

Physiological Assessment of Delirium Severity: The Electroencephalographic Confusion Assessment Method Severity Score (E-CAM-S) van Sleuwen, M. Sun, H. Eckhardt, C. Neelagiri, A. Tesh, R. A. Westmeijer, M. Paixao, L. Rajan, S. Velpula Krishnamurthy, P. Sikka, P. Leone, M. J. Panneerselvam, E. Quadri, S. A. Akeju, O. Kimchi, E. Y. Westover, M. B. Crit Care Med 2021

van Sleuwen, M.
Sun, H.
Eckhardt, C.
Neelagiri, A.
Tesh, R. A.
Westmeijer, M.
Paixao, L.
Rajan, S.
Velpula Krishnamurthy, P.
Sikka, P.
Leone, M. J.
Panneerselvam, E.
Quadri, S. A.
Akeju, O.
Kimchi, E. Y.
Westover, M. B.

The effect of peri-operative dexmedetomidine on the incidence of postoperative delirium in cardiac and non-cardiac surgical patients: a randomised, double-blind placebo-controlled trial van Norden, J. Spies, C. D. Borchers, F. Mertens, M. Kurth, J. Heidgen, J. Pohrt, A. Mueller, A. Anaesthesia 2021

Aged
Berlin/epidemiology
Dexmedetomidine/*therapeutic use
Double-Blind Method
Emergence Delirium/*epidemiology/*prevention & control
Female
Humans
Hypnotics and Sedatives/*therapeutic use
Incidence
Length of Stay/statistics & numerical data
Male
Perioperative Care/*methods
Prospective Studies
*Surgical Procedures, Operative
delirium
dexmedetomidine
peri-operative
trial

Rivastigmine for minor visual hallucinations in Parkinson's disease: A randomized controlled trial with 24 months follow-up van Mierlo, T. J. M. Foncke, E. M. J. Post, B. Schmand, B. A. Bloem, B. R. van Harten, B. Tissingh, G. Munts, A. G. de Haan, R. J. de Bie, R. M. A. Brain Behav 2021

Cholinesterase Inhibitors
Follow-Up Studies
Hallucinations/drug therapy
Humans
*Parkinson Disease/complications/drug therapy
Phenylcarbamates
Rivastigmine
*Parkinson’s disease
*cholinesterase inhibitors
*hallucinations
*psychosis
*randomized controlled trial

Effects of Orthogeriatric Care Models on Outcomes of Hip Fracture Patients: A Systematic Review and Meta-Analysis Van Heghe, A. Mordant, G. Dupont, J. Dejaeger, M. Laurent, M. R. Gielen, E. Calcif Tissue Int 2021

Geriatric co-management
Hip fracture
Meta-analysis
Orthogeriatrics
Osteoporosis
Systematic review

Automatic continuous EEG signal analysis for diagnosis of delirium in patients with sepsis Urdanibia-Centelles, O. Nielsen, R. M. Rostrup, E. Vedel-Larsen, E. Thomsen, K. Nikolic, M. Johnsen, B. Møller, K. Lauritzen, M. Benedek, K. Clin Neurophysiol 2021

Automatic EEG
Delirium
Eeg
Prognostication
Sepsis
cEEG

Evaluation of the effectiveness of delirium prevention care protocol for the patients with hip fracture: A randomised controlled study Unal, N. Guvenc, G. Ilkin Naharci, M. J Clin Nurs 2021

nursing care
older patients
orthopaedics
pain
patient
protocol
sleep quality

Association of poor sleep burden in middle age and older adults with risk for delirium during hospitalization Ulsa, M. C. Zheng, X. Li, P. Gaba, A. Wong, P. M. Saxena, R. Scheer, F. Rutter, M. Akeju, O. Hu, K. Gao, L. J Gerontol A Biol Sci Med Sci 2021

Sleep health
chronotype
circadian rhythms
napping
perioperative neurocognitive disorders

Where should patients with or at risk of delirium be treated in an acute care system? Comparing the rates of delirium in patients receiving usual care vs alternative care: A systematic review and meta-analysis Ukwuoma Ekeozor, C. Jeyaruban, D. Lasserson, D. Int J Clin Pract 2021

Critical Care
*Delirium/prevention & control
Humans
Incidence
acute care
comparing, usual care
delirium
hospitalised patients
interventions
prevention
systematic review

Restraint use in the acute-care hospital setting: A cross-sectional multi-centre study Thomann, S. Zwakhalen, S. Richter, D. Bauer, S. Hahn, S. Int J Nurs Stud 2021

Cross-Sectional Studies
*Hospitals
Humans
Long-Term Care
*Restraint, Physical
Switzerland
Health-care outcome and process assessment
Hospitals
Prevalence
Restraints
Risk factors

Immune, Blood Cell, and Blood Gas Biomarkers of Delirium in Elderly Individuals with Hip Fracture Surgery Thisayakorn, P. Tangwongchai, S. Tantavisut, S. Thipakorn, Y. Sukhanonsawat, S. Wongwarawipat, T. Sirivichayakul, S. Maes, M. Dement Geriatr Cogn Disord 2021

Delirium
Inflammation
Neuroimmune
Neutrophils
Oxidative stress
Psychiatry

Delirium Associations with Antibiotics: A Pharmacovigilance Study of the FDA Adverse Event Reporting System (FAERS) Teng, C. Frei, C. R. Drugs Real World Outcomes 2021

Delirium, Antibiotics, FDA Adverse Event Reporting System

The Impact of Aging on Symptom Prevalence and Management in Terminally ill Patients With Cancer Tatokoro, M. Matsuo, N. J Pain Symptom Manage 2021

Age
cancer
opioid
palliative care unit
palliative sedation
symptom prevalence

Subjective strain of care experienced by pulmonary and critical care medical nurses when caring for patients with delirium: a cross-sectional study Tan, H. Zhou, L. Wu, S. Dong, Q. Yang, L. Xu, J. Zhao, S. Wang, X. Yang, H. BMC Health Serv Res 2021

Critical Care
Cross-Sectional Studies
*Delirium/epidemiology/therapy
Humans
*Nurses
*Nursing Staff, Hospital
Critical care nursing
Delirium
Nursing strain of care
Pulmonary care

Circulating MicroRNAs and Novel Proteins as Potential Biomarkers of Neurological Complications after Heart Bypass Surgery Szwed, K. Szwed, M. Kozakiewicz, M. Karłowska-Pik, J. Soja-Kukieła, N. Bartoszewska, A. Borkowska, A. J Clin Med 2021

Cabg
Pocd
biomarker
cardiac surgery
clinical study
coronary artery bypass grafting
delirium
microRNA
neurological complications
postoperative cognitive dysfunction

Evaluation of the implementation of multidisciplinary fast-track program for acute geriatric hip fractures at a University Hospital in resource-limited settings Sura-Amonrattana, U. Tharmviboonsri, T. Unnanuntana, A. Tantigate, D. Srinonprasert, V. BMC Geriatr 2021

Aged
Aged, 80 and over
*Hip Fractures/diagnosis/epidemiology/surgery
Hospital Mortality
Hospitalization
Hospitals, University
Humans
Length of Stay
Retrospective Studies
*Complications
*Delirium
*Dementia
*Elderly
*Hip fracture
*Length of stay
*Mortality
*Orthogeriatric

Perceptions of current occupational therapy practice with older adults experiencing delirium Strecker, C. Hitch, D. Australas J Ageing 2021

Aged
Australia
Cross-Sectional Studies
*Delirium/diagnosis/therapy
Humans
*Occupational Therapy
Perception
delirium
occupational therapy
professional practice

Changes in autonomic tone during delirium in acute stroke patients assessed by pupillometry and skin conductance Stokholm, J. Birkmose, L. K. H. Ahmed, Aabo Csillag, C. Kjær, T. W. Christensen, T. J Neurol Sci 2021

Autonomic Nervous System
*Brain Ischemia
Cohort Studies
*Delirium/diagnosis/etiology
Humans
Reflex, Pupillary
*Stroke/complications
*Autonomic nervous system
*Delirium
*Stroke

Expression of HO1 and PER2 can predict the incidence of delirium in trauma patients with concomitant brain injury Steimer, M. Kaiser, S. Ulbrich, F. Kalbhenn, J. Bürkle, H. Schallner, N. Sci Rep 2021

Biomarkers, Circadian rhythms and sleep, Translational research, Neurological manifestations

An implementation science approach to geriatric screening in an emergency department Southerland, L. T. Hunold, K. M. Van Fossen, J. Caterino, J. M. Gulker, P. Stephens, J. A. Bischof, J. J. Farrell, E. Carpenter, C. R. Mion, L. C. J Am Geriatr Soc 2021

Cfir
emergency department
implementation
screening tools

Effectiveness of the ABCDEF bundle on delirium, functional outcomes and quality of life in intensive care patients: a study protocol for a randomised controlled trial with embedded process evaluation Sosnowski, K. Mitchell, M. Cooke, M. White, H. Morrison, L. Lin, F. BMJ Open 2021

Critical Care
Critical Illness
*Delirium/prevention & control
Humans
Intensive Care Units
*Quality of Life
Randomized Controlled Trials as Topic
*adult intensive & critical care
*delirium & cognitive disorders
*pain management

Effects of general versus subarachnoid anaesthesia on circadian melatonin rhythm and postoperative delirium in elderly patients undergoing hip fracture surgery: A prospective cohort clinical trial Song, Y. Liu, Y. Yuan, Y. Jia, X. Zhang, W. Wang, G. Jia, Y. Wang, X. Liu, L. Li, W. Li, X. Cai, N. Liu, C. Li, Y. Han, Y. Zhou, Y. Mi, X. Shi, C. Wang, J. Q. Vuylsteke, A. Guo, X. Li, Z. EBioMedicine 2021

Circadian rhythm
general anaesthesia
melatonin
postoperative delirium
subarachnoid anaesthesia

Comparison of the Effects of Haloperidol and Dexmedetomidine on Delirium and Agitation in Patients with a Traumatic Brain Injury Admitted to the Intensive Care Unit Soltani, F. Tabatabaei, S. Jannatmakan, F. Nasajian, N. Amiri, F. Darkhor, R. Moravej, M. Anesth Pain Med 2021

Delirium
Dexmedetomidine
Haloperidol
Icu
Traumatic Brain Injury

Comparison of postoperative delirium within 24 hours between ketamine and propofol infusion during cardiopulmonary bypass machine: A randomized controlled trial Siripoonyothai, S. Sindhvananda, W. Ann Card Anaesth 2021

*Cardiac surgery
*ketamine
*postoperative delirium
*propofol

Improving delirium detection in intensive care units: Multicomponent education and training program Sinvani, L. Delle Site, C. Laumenede, T. Patel, V. Ardito, S. Ilyas, A. Hertz, C. Wolf-Klein, G. Pekmezaris, R. Hajizadeh, N. Thomas, L. J Am Geriatr Soc 2021

critical care nursing
delirium
intensive care units
telemedicine

Outcome, demography and resource utilization in ICU Patients with delirium and malignancy Sieber, M. Rudiger, A. Schüpbach, R. Krüger, B. Schubert, M. Bettex, D. Sci Rep 2021

Medical research, Oncology, Delirium, ICU delirium, ICDSC, Malignancies

Prevalence of postoperative delirium with different combinations of intraoperative general anesthetic agents in patients undergoing cardiac surgery: A retrospective propensity-score-matched study Shin, H. J. Choi, S. L. Na, H. S. Medicine (Baltimore) 2021

Aged
Anesthetics, General/*adverse effects/therapeutic use
Cardiac Surgical Procedures/adverse effects/methods
Delirium/epidemiology
Female
Humans
Incidence
Logistic Models
Male
Middle Aged
Postoperative Complications/epidemiology
*Prevalence
Propensity Score
Retrospective Studies

Is Comprehensive Geriatric Assessment Admission Avoidance Hospital at Home an Alternative to Hospital Admission for Older Persons? : A Randomized Trial Shepperd, S. Butler, C. Cradduck-Bamford, A. Ellis, G. Gray, A. Hemsley, A. Khanna, P. Langhorne, P. Mort, S. Ramsay, S. Schiff, R. Stott, D. J. Wilkinson, A. Yu, L. M. Young, J. Ann Intern Med 2021

Aged
Aged, 80 and over
Cost Control
Geriatric Assessment/*methods
*Home Care Services/economics
Humans
Long-Term Care/economics
Outcome Assessment, Health Care
Patient Admission/economics
Residential Facilities/economics
United Kingdom

Delirium and abnormal autonomic nervous system response to head-up tilt testing Shanahan, E. Ryan, S. Leahy, A. Sheehy, T. Costelloe, A. Roy, A. Galvin, R. Peters, C. Lyons, D. O'Connor, M. Exp Gerontol 2021

Aged, 80 and over
Autonomic Nervous System
Blood Pressure
*Delirium/diagnosis
Humans
*Hypotension, Orthostatic
Prospective Studies
Tilt-Table Test
*Autononic impairment
*Delirium
*Orthostatic hypertension
*Orthostatic hypotension

Understanding frailty among older people living in old age homes and the community in Nepal: A cross-sectional study Shah, R. Carandang, R. R. Shibanuma, A. Ong, K. I. C. Kiriya, J. Jimba, M. PLoS One 2021

Activities of Daily Living
Aged
Aged, 80 and over
Cross-Sectional Studies
Female
Frail Elderly/*psychology
Frailty/*epidemiology
Geriatric Assessment
Homes for the Aged/*statistics & numerical data
Humans
Independent Living/psychology/*statistics & numerical data
Interviews as Topic
Linear Models
Male
Middle Aged
Nepal
Socioeconomic Factors

Death in delirious palliative-care patients occurs irrespective of age: A prospective, observational cohort study of 229 delirious palliative-care patients Seiler, A. Blum, D. Hertler, C. Schettle, M. Zipser, C. M. Bode, L. Gehrke, S. Ernst, J. Schubert, M. von Känel, R. Boettger, S. Palliat Support Care 2021

Aged
*Delirium/complications/mortality
*Hospital Mortality
Humans
Length of Stay
*Palliative Care
Prospective Studies
Risk Factors
*Delirium
*Palliative-care patients
*Precipitating factors
*Predisposing factors

Delirium Variability is Influenced by the Sound Environment (DEVISE Study): How Changes in the Intensive Care Unit soundscape affect delirium incidence Sangari, A. Emhardt, E. A. Salas, B. Avery, A. Freundlich, R. E. Fabbri, D. Shotwell, M. S. Schlesinger, J. J. J Med Syst 2021

Critical Care
*Delirium/epidemiology
Humans
Incidence
Intensive Care Units
Critical care medicine
Delirium
Intensive care unit
Risk factor
Sound

Delirium in Intensive Care Units: Perceptions of Physicians and Nurses Salameh, B. Al Razeeni, D. M. Mansor, K. Abdallah, J. M. Ayed, A. Salem, H. Crit Care Nurs Q 2021

Critical Care
*Delirium/diagnosis
Health Knowledge, Attitudes, Practice
Humans
Intensive Care Units
*Nurses
*Nursing Staff, Hospital
Perception
*Physicians
Surveys and Questionnaires

How to deal with the consent of adults with cognitive impairment involved in European geriatric living labs? Sacco, G. Noublanche, F. Blazek, F. Hue, C. Carballido, L. Asfar, M. Allain, P. Annweiler, C. Philos Ethics Humanit Med 2021

Aged
*Cognitive Dysfunction
Confusion
Humans
*Informed Consent
*Consent
*Ethics
*Geriatrics
*Living lab

Management of preoperative pain in elderly patients with moderate to severe cognitive deficits and hip fracture: a retrospective, monocentric study in an orthogeriatric unit Ruel, M. Boussat, B. Boudissa, M. Garnier, V. Bioteau, C. Tonetti, J. Pailhe, R. Gavazzi, G. Drevet, S. BMC Geriatr 2021

Aged
Aged, 80 and over
Cognition
*Hip Fractures/complications/diagnosis/epidemiology
Hospitalization
Humans
Pain
Retrospective Studies
*Cognitive deficits
*Elderly
*Hip fracture
*Opioids
*Orthogeriatric
*Pain
*Preoperative

Early high-dose vitamin C in post-cardiac arrest syndrome (VITaCCA): study protocol for a randomized, double-blind, multi-center, placebo-controlled trial Rozemeijer, S. de Grooth, H. J. Elbers, P. W. G. Girbes, A. R. J. den Uil, C. A. Dubois, E. A. Wils, E. J. Rettig, T. C. D. van Zanten, A. R. H. Vink, R. van den Bogaard, B. Bosman, R. J. Oudemans-van Straaten, H. M. de Man, A. M. E. Trials 2021

Ascorbic Acid
Double-Blind Method
Humans
Multicenter Studies as Topic
Organ Dysfunction Scores
*Post-Cardiac Arrest Syndrome
Randomized Controlled Trials as Topic
Treatment Outcome
Cardiac arrest
Free radicals
Ischemia/reperfusion injury
Out-of-hospital cardiac arrest
Oxidative stress
Post-cardiac arrest syndrome
Reactive oxygen species
Vitamin C

Synergistic Impact of Systolic Blood Pressure and Perfusion Status on Mortality in Acute Heart Failure Rossello, X. Bueno, H. Gil, V. Jacob, J. Martín-Sánchez, F. J. Llorens, P. Herrero Puente, P. Alquézar-Arbé, A. Espinosa, B. Raposeiras-Roubín, S. Müller, C. E. Mebazaa, A. Maggioni, A. P. Pocock, S. Chioncel, O. Miró, Ò Circ Heart Fail 2021

Acute Disease
Aged
Aged, 80 and over
Blood Pressure/physiology
Cerebrovascular Circulation
Confusion/*physiopathology
Emergency Service, Hospital
Female
Heart Failure/*physiopathology
Humans
Hypotension/*physiopathology
Livedo Reticularis/*physiopathology
Logistic Models
Male
*Mortality
Odds Ratio
Pallor/*physiopathology
Prognosis
Regional Blood Flow
Skin/blood supply
Skin Temperature/physiology
Spain
Systole
*blood pressure
*heart failure
*prognosis

The Impact of Nursing Delirium Preventive Interventions in the ICU: A Multicenter Cluster-randomized Controlled Clinical Trial Rood, P. J. T. Zegers, M. Ramnarain, D. Koopmans, M. Klarenbeek, T. Ewalds, E. van der Steen, M. S. Oldenbeuving, A. W. Kuiper, M. A. Teerenstra, S. Adang, E. van Loon, L. M. Wassenaar, A. Vermeulen, H. Pickkers, P. van den Boogaard, M. Am J Respir Crit Care Med 2021

Aged
Aged, 80 and over
Coma/etiology/nursing/prevention & control
Combined Modality Therapy
Critical Care/*methods
Critical Care Nursing/*methods
Delirium/etiology/*nursing/*prevention & control
Female
Follow-Up Studies
Humans
Intensive Care Units
Male
Middle Aged
Risk Factors
Treatment Outcome
Young Adult
*critical care
*delirium
*intervention program
*nonpharmacological
*nursing

Heart rate variability and delirium in acute non-cardioembolic stroke: a prospective, cross-sectional, cohort study Rollo, E. Marotta, J. Callea, A. Brunetti, V. Vollono, C. Scala, I. Imperatori, C. Frisullo, G. Broccolini, A. Della Marca, G. Neurol Sci 2021

Autonomic
Cam-icu
Delirium
Heart rate variability
Stroke
Stroke unit

The training needs of Korean intensive care unit nurses regarding delirium Roh, Y. S. Intensive Crit Care Nurs 2021

Clinical Competence
Cross-Sectional Studies
*Delirium
Humans
Intensive Care Units
*Nurses
Republic of Korea
Delirium
Intensive care unit
Nurses
Survey

Hospitalisation without delirium is not associated with cognitive decline in a population-based sample of older people-results from a nested, longitudinal cohort study Richardson, S. J. Lawson, R. Davis, D. H. J. Stephan, B. C. M. Robinson, L. Matthews, F. E. Brayne, C. Barnes, L. E. Taylor, J. P. Parker, S. G. Allan, L. M. Age Ageing 2021

Aged
*Cognitive Dysfunction
Cohort Studies
*Delirium/diagnosis/epidemiology
Hospitalization
Humans
Longitudinal Studies
*cognitive outcomes
*cohort study
*delirium
*hospitalised older adults

Recurrent delirium over 12 months predicts dementia: results of the Delirium and Cognitive Impact in Dementia (DECIDE) study Richardson, S. J. Davis, D. H. J. Stephan, B. C. M. Robinson, L. Brayne, C. Barnes, L. E. Taylor, J. P. Parker, S. G. Allan, L. M. Age Ageing 2021

Cognition
*Cognitive Dysfunction
*Delirium/diagnosis/epidemiology
*Dementia/diagnosis/epidemiology
Humans
Prospective Studies
*cohort study
*delirium
*dementia
*epidemiology
*older people

Serum Proteomics of Older Patients Undergoing Major Cardiac Surgery: Identification of Biomarkers Associated With Postoperative Delirium Rhee, J. Kuznetsov, A. McKay, T. Lyons, M. Houstis, N. Mekkonen, J. Ethridge, B. Ibala, R. Hahm, E. Gitlin, J. Guseh, J. S. Kitchen, R. Rosenzweig, A. Shaefi, S. Flaczyk, A. Qu, J. Akeju, O. Front Aging Neurosci 2021

*il-6
*pde3a
*SOMAscan
*timp-1
*TruCulture
*cardiopulmonary bypass
*postoperative delirium
*proteomics

Comparison of Esophagectomy outcomes between a National Center, a National Audit Collaborative, and an International database using the Esophageal Complications Consensus Group (ECCG) standardized definitions Reynolds, J. V. Donlon, N. Elliott, J. A. Donohoe, C. Ravi, N. Kuppusamy, M. K. Low, D. E. Dis Esophagus 2021

Aged
Anastomotic Leak/epidemiology/etiology
Consensus
*Esophageal Neoplasms/surgery
*Esophagectomy/adverse effects
Female
Humans
Male
Postoperative Complications/epidemiology/etiology
Retrospective Studies
complications
esophageal cancers
esophagectomy

Health Profiles, Health Services Use, and Transition to Dementia in Inpatients With Late-Life Depression and Other Mental Illnesses Reppermund, S. Heintze, T. Srasuebkul, P. Trollor, J. N. J Am Med Dir Assoc 2021

Aged
Australia/epidemiology
*Dementia/epidemiology
Depression/epidemiology
Humans
*Inpatients
Length of Stay
Male
New South Wales
Retrospective Studies
Risk Factors
*Depression
*data linkage
*dementia
*mental disorders
*older adults

A Survey of Nurses' Perspectives on Delirium Screening in Older Adult Medical Inpatients With Limited English Proficiency Reppas-Rindlisbacher, C. Panov, E. D. Cuperfain, A. B. Rawal, S. J Gerontol Nurs 2021

Aged
*Delirium/diagnosis
Health Knowledge, Attitudes, Practice
Humans
Inpatients
*Limited English Proficiency
*Nurses

Post-hospital falls incidence and risk factors among older adults: a systematic review and meta-analysis Qian, X. X. Chen, Z. Fong, D. Y. T. Ho, M. Chau, P. H. Age Ageing 2021

incidence
meta-analysis
older population
post-hospital Falls
risk factors

The prevalence of serotonin syndrome in an intensive care unit: A prospective observational study Prakash, S. Rathore, C. Rana, K. J Crit Care 2021

Adult
Humans
Intensive Care Units
Male
Middle Aged
Prevalence
Prospective Studies
*Respiratory Insufficiency
*Serotonin Syndrome/chemically induced/diagnosis/epidemiology
*Cyproheptadine
*Serotonin syndrome
*Serotonin toxicity

Associations of subclinical heart failure and atrial fibrillation with mild cognitive impairment: a cross-sectional study in a subclinical heart failure screening programme Potter, E. L. Ramkumar, S. Wright, L. Marwick, T. H. BMJ Open 2021

Aged
*Atrial Fibrillation/diagnosis/epidemiology
Australia/epidemiology
*Cognitive Dysfunction/diagnosis/epidemiology
Cross-Sectional Studies
*Heart Failure
Humans
*delirium & cognitive disorders
*preventive medicine

A One-Day Prospective National Observational Study on Sedation-Analgesia of Patients with Brain Injury in French Intensive Care Units: The SEDA-BIP-ICU (Sedation-Analgesia in Brain Injury Patient in ICU) Study Poignant, S. Vigué, B. Balram, P. Biais, M. Carillon, R. Cottenceau, V. Dahyot-Fizelier, C. Degos, V. Geeraerts, T. Jeanjean, P. Vega, E. Lasocki, S. Espitalier, F. Laffon, M. Neurocrit Care 2021

Brain injury
Intensive care unit
Sedation-analgesia

Risk factors and adverse clinical outcomes of postoperative delirium in Thai elderly patients: A prospective cohort study Pipanmekaporn, T. Punjasawadwong, Y. Wongpakaran, N. Wongpakaran, T. Suwannachai, K. Chittawatanarat, K. Mueankwan, S. Perspect Psychiatr Care 2021

Aged
*Delirium/epidemiology
Humans
*Postoperative Complications/epidemiology
Prospective Studies
Risk Factors
Thailand/epidemiology
adverse clinical outcomes
elderly patients
mortality
postoperative delirium

Multifaceted intervention including Facebook-groups to improve guideline-adherence in ICU: A quasi-experimental interrupted time series study Petosic, A. Småstuen, M. C. Beeckman, D. Flaatten, H. Sunde, K. Wøien, H. Acta Anaesthesiol Scand 2021

agitation/sedation
delirium
facebook
guideline adherence
intensive care unit
interrupted time series
multifacetted intervention
pain
quality improvement
quasi experimental
social media
social networking sites

Perioperative Optimization of Senior Health in Spine Surgery: Impact on Postoperative Delirium Pernik, M. N. Deme, P. R. Nguyen, M. L. Aoun, S. G. Adogwa, O. Hall, K. Stewart, N. A. Dosselman, L. J. El Tecle, N. E. McDonald, S. R. Bagley, C. A. Wingfield, S. A. J Am Geriatr Soc 2021

Aged
Delirium/epidemiology/*prevention & control
Elective Surgical Procedures/*adverse effects
Female
Geriatric Assessment
Health Plan Implementation
Humans
Incidence
Male
Patient Care Team
Perioperative Care/*methods
Postoperative Cognitive Complications/epidemiology/*prevention & control
Program Evaluation
Retrospective Studies
Spine/*surgery
*deformity
*delirium
*geriatric
*interdisciplinary | surgery
*prevention
*spine

Postoperative delirium mediates 180-day mortality in orthopaedic trauma patients Pedemonte, J. C. Sun, H. Franco-Garcia, E. Zhou, C. Heng, M. Quraishi, S. A. Westover, B. Akeju, O. Br J Anaesth 2021

Aged
Aged, 80 and over
Emergence Delirium/diagnosis/*mortality
Female
Frail Elderly
Frailty/diagnosis/*mortality/*surgery
Geriatric Assessment/methods
Humans
Male
Mortality/trends
Orthopedic Procedures/*mortality/trends
Retrospective Studies
Time Factors
Wounds and Injuries/diagnosis/*mortality/*surgery
*frailty
*mortality
*orthopaedic trauma
*perioperative
*postoperative delirium