What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) for the diagnosis of delirium in adults in critical care settings
- Authors
- Miranda, F. Gonzalez, F. Plana, M. N. Zamora, J. Quinn, T. J. Seron, P.
- Year
- 2023
- Journal
- Cochrane Database Syst Rev
- Abstract
BACKGROUND: Delirium is an underdiagnosed clinical syndrome typified by an acute alteration of mental state. It is an important problem in critical care and intensive care units (ICU) due to its high prevalence and its association with adverse outcomes. Delirium is a very distressing condition for patients, with a huge impact on their well-being. Diagnosis of delirium in the critical care setting is challenging. This is especially true for patients who are mechanically ventilated and are therefore unable to engage in a verbal interview. The Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) is a tool specifically designed to assess for delirium in the context of ICU patients, including those on mechanical ventilation. CAM-ICU can be administered by non-specialists to give a dichotomous delirium present/absent result. OBJECTIVES: To determine the diagnostic accuracy of the CAM-ICU for the diagnosis of delirium in adult patients in critical care units. SEARCH METHODS: We searched MEDLINE (Ovid SP, 1946 to 8 July 2022), Embase (Ovid SP, 1982 to 8 July 2022), Web of Science Core Collection (ISI Web of Knowledge, 1945 to 8 July 2022), PsycINFO (Ovid SP, 1806 to 8 July 2022), and LILACS (BIREME, 1982 to 8 July 2022). We checked the reference lists of included studies and other resources for additional potentially relevant studies. We also searched the Health Technology Assessment database, the Cochrane Library, Aggressive Research Intelligence Facility database, WHO ICTRP, ClinicalTrials.gov, and websites of scientific associations to access any annual meetings and abstracts of conference proceedings in the field. SELECTION CRITERIA: We included diagnostic studies enrolling adult ICU patients assessed using the CAM-ICU tool, regardless of language or publication status and reporting sufficient data on delirium diagnosis for the construction of 2 x 2 tables. Eligible studies evaluated the diagnostic performance of the CAM-ICU versus a clinical reference standard based on any iteration of the Diagnostic and Statistical Manual of Mental Disorders (DSM) criteria applied by a clinical expert. DATA COLLECTION AND ANALYSIS: Two review authors independently selected and collated study data. We assessed the methodological quality of studies using the QUADAS-2 tool. We used two univariate fixed-effect or random-effects models to determine summary estimates of sensitivity and specificity. We performed sensitivity analyses that excluded studies considered to be at high risk of bias and high concerns in applicability, due mainly to the target population included (e.g. patients with traumatic brain injury). We also investigated potential sources of heterogeneity, assessing the effect of reference standard diagnosis and proportion of patients ventilated. MAIN RESULTS: We included 25 studies (2817 participants). The mean age of participants ranged from 48 to 69 years; 15 of the studies included critical care units admitting mixed populations (e.g. medical, trauma, surgery patients). The percentage of patients receiving mechanical ventilation ranged from 11.8% to 100%. The prevalence of delirium in the studies included ranged from 12.5% to 83.9%. Presence of delirium was determined by the application of DSM-IV criteria in 13 out of 25 included studies. We assessed 13 studies as at low risk of bias and low applicability concerns for all QUADAS-2 domains. The most common issue of concern was flow and timing of the tests, followed by patient selection. Overall, we estimated a pooled sensitivity of 0.78 (95% confidence interval (CI) 0.72 to 0.83) and a pooled specificity of 0.95 (95% CI 0.92 to 0.97). Sensitivity analysis restricted to studies at low risk of bias and without any applicability concerns (n = 13 studies) gave similar summary accuracy indices (sensitivity 0.80 (95% CI 0.72 to 0.86), specificity 0.95 (95% CI 0.93 to 0.97)). Subgroup analyses based on diagnostic assessment found summary estimates of sensitivity and specificity for studies using DSM-IV of 0.79 (95% CI 0.72 to 0.85) and 0.94 (95% CI 0.90 to 0.96). For studies that used DSM-5 criteria, summary estimates of sensitivity and specificity were 0.75 (95% CI 0.67 to 0.82) and 0.98 (95% CI 0.95 to 0.99). DSM criteria had no significant effect on sensitivity (P = 0.421), but the specificity for detection of delirium was higher when DSM-5 criteria were used (P = 0.024). The relative specificity comparing DSM-5 versus DSM-IV criteria was 1.05 (95% CI 1.02 to 1.08). Summary estimates of sensitivity and specificity for studies recruiting < 100% of patients with mechanical ventilation were 0.81 (95% CI 0.75 to 0.85) and 0.95 (95% CI 0.91 to 0.98). For studies that exclusively recruited patients with mechanical ventilation, summary estimates of sensitivity and specificity were 0.91 (95% CI 0.76 to 0.97) and 0.98 (95% CI 0.92 to 0.99). Although there was a suggestion of differential performance of CAM-ICU in ventilated patients, the differences were not significant in sensitivity (P = 0.316) or in specificity (P = 0.493). AUTHORS’ CONCLUSIONS: The CAM-ICU tool may have a role in the early identification of delirium, in adult patients hospitalized in intensive care units, including those on mechanical ventilation, when non-specialized, properly trained clinical personnel apply the CAM-ICU. The test is most useful for exclusion of delirium. The test may miss a proportion of patients with incident delirium, therefore in situations where detection of all delirium cases is desirable, it may be best to repeat the test or combine CAM-ICU with another assessment. Future studies should compare different screening tests proposed for bedside assessment of delirium, as this approach will reveal which tool yields superior accuracy. In addition, future studies should consider and report the flow and timing of the tests and clearly report key characteristics related to patient selection. Finally, future research should focus on the impact of CAM-ICU screening on patient outcomes.
- PMID
PMID: 37987526
- Keywords
Adult
Humans
Middle Aged
Aged
*Intensive Care Units
Sensitivity and Specificity
*Delirium/diagnosis
Critical Care
- Page(s)
- Volume
- Issue
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| Three-Minute Diagnostic Assessment for Delirium using the Confusion Assessment Method (3D-CAM): French translation and cultural adaptation | Gaudet, J. G. Kull, C. Eskenazi, M. L. Diaper, J. Maillard, J. Mollard, F. Marti, C. Marcantonio, E. R. Courvoisier, D. S. Walder, B. | Can J Anaesth | 2022 |
3d-cam |
| Critical role of acute hypoxemia on the cognitive impairment after severe COVID-19 pneumonia: a multivariate causality model analysis | García-Grimshaw, M. Chirino-Pérez, A. Flores-Silva, F. D. Valdés-Ferrer, S. I. Vargas-Martínez, MlÁ Jiménez-Ávila, A. I. Chávez-Martínez, O. A. Ramos-Galicia, E. M. Marché-Fernández, O. A. Ramírez-Carrillo, M. F. Grajeda-González, S. L. Ramí | Neurol Sci | 2022 |
Adolescent |
| Prevalence, risk factors, and outcomes of subsyndromal delirium in older adults in hospital or long-term care settings: A systematic review and meta-analysis | Gao, Y. Gao, R. Yang, R. Gan, X. | Geriatr Nurs | 2022 |
Older adults |
| Hospital-treated deliberate self-poisoning patients: Drug-induced delirium and clinical outcomes | Gale, L. McGill, K. Twaddell, S. Whyte, I. M. Lewin, T. J. Carter, G. L. | Aust N Z J Psychiatry | 2022 |
Aged |
| An Inpatient Geriatrics Program with a Focus on Any Type of Cognitive Impairment Reduces Mortality | Flaherty, J. H. Bloomstone, J. A. Vicents Sande, E. Brantley, A. Semien, G. A. | J Nutr Health Aging | 2022 |
Aged |
| Risk factors for delirium in adult patients receiving specialist palliative care: A systematic review and meta-analysis | Featherstone, I. Sheldon, T. Johnson, M. Woodhouse, R. Boland, J. W. Hosie, A. Lawlor, P. Russell, G. Bush, S. Siddiqi, N. | Palliat Med | 2022 |
Adult |
| Incidence of postoperative delirium in patients with preoperative and postoperative Obstructive Sleep Apnea Syndrome. A Systematic Review of the literature | Dooijeweerd, S. Torensma, B. Faraj, D. Eldawlatly, A. A. | Saudi J Anaesth | 2022 |
Delirium |
| The relationship between body mass index and postoperative delirium | Deng, X. Qin, P. Lin, Y. Tao, H. Liu, F. Lin, X. Wang, B. Bi, Y. | Brain Behav | 2022 |
body mass index |
| Pretransplant physical frailty, postoperative delirium, and short-term outcomes among older lung transplant recipients | Dalton, T. Snyder, L. Buckley, E. B. Smith, P. | Exp Gerontol | 2022 |
Delirium |
| Effects of dexmedetomidine on surgery for type A acute aortic dissection outcome | Cheng, Y. T. Lee, K. T. Chang, C. H. Wu, V. C. Chan, Y. S. Chen, D. Y. Chu, P. H. Chou, A. H. Liu, K. S. Chen, S. W. | Sci Rep | 2022 |
*Acute Kidney Injury/etiology/mortality/therapy |
| Global research trends in perioperative care for the elderly: a bibliometric and visualized study | Chen, Q. Wang, Y. Song, S. Xie, G. Cheng, B. Fang, X. | J Anesth | 2022 |
Aged |
| Assessment of potential selection bias in neuroimaging studies of postoperative delirium and cognitive decline: lessons from the SAGES study | Cavallari, M. Fong, T. G. Touroutoglou, A. Dickerson, B. C. Schmitt, E. Travison, T. G. Marcantonio, E. R. Ngo, L. H. Libermann, T. Pascual-Leone, A. Shafi, M. M. Inouye, S. K. Jones, R. N. | Brain Imaging Behav | 2022 |
Aging |
| Health outcomes after the implementation of multidisciplinary clinical guidelines for the care of hip fractures | Casanova Querol, T. Santiago Bautista, J. M. Lafuente Salinas, M. Güell Farré, E. Girós Torres, J. Martín-Baranera, M. Miralles Basseda, R. | Rev Clin Esp (Barc) | 2022 |
Aged |
| Health outcomes after the implementation of multidisciplinary clinical guidelines for the care of hip fractures | Casanova Querol, T. Santiago Bautista, J. M. Lafuente Salinas, M. Güell Farré, E. Girós Torres, J. Martín-Baranera, M. Miralles Basseda, R. | Rev Clin Esp (Barc) | 2022 |
Aged |
| Health outcomes after the implementation of multidisciplinary clinical guidelines for the care of hip fractures | Casanova Querol, T. Santiago Bautista, J. M. Lafuente Salinas, M. Güell Farré, E. Girós Torres, J. Martín-Baranera, M. Miralles Basseda, R. | Rev Clin Esp (Barc) | 2022 |
Aged |
| Melatonin in ICU delirium: shining light on the hormone of darkness | Burry, L. Sonneville, R. Ely, E. W. | Intensive Care Med | 2022 | |
| The association between the inflammatory response following surgery and post-operative delirium in older oncological patients: a prospective cohort study | Brattinga, B. Plas, M. Spikman, J. M. Rutgers, A. de Haan, J. J. Absalom, A. R. van der Wal-Huisman, H. de Bock, G. H. van Leeuwen, B. L. | Age Ageing | 2022 |
Aged |
| Brain Network Dysfunction in Poststroke Delirium and Spatial Neglect: An fMRI Study | Boukrina, O. Kowalczyk, M. Koush, Y. Kong, Y. Barrett, A. M. | Stroke | 2022 |
Adult |
| Postoperative delirium prediction using machine learning models and preoperative electronic health record data | Bishara, A. Chiu, C. Whitlock, E. L. Douglas, V. C. Lee, S. Butte, A. J. Leung, J. M. Donovan, A. L. | BMC Anesthesiol | 2022 |
Aged |
| High-dose preoperative glucocorticoid for prevention of emergence and postoperative delirium in liver resection: A double-blinded randomized clinical trial substudy | Awada, H. N. Steinthorsdottir, K. J. Schultz, N. A. Hillingsø, J. G. Larsen, P. N. Jans, Ø Kehlet, H. Aasvang, E. K. | Acta Anaesthesiol Scand | 2022 |
emergence |
| Grip strength as a predictor of postoperative delirium in patients with colorectal cancers | Arita, A. Takahashi, H. Ogino, T. Miyoshi, N. Uemura, M. Akasaka, H. Sugimoto, K. Rakugi, H. Doki, Y. Eguchi, H. | Ann Gastroenterol Surg | 2022 |
colorectal cancer |
| Positive scores on the 4AT delirium assessment tool at hospital admission are linked to mortality, length of stay and home time: two-centre study of 82,770 emergency admissions | Anand, A. Cheng, M. Ibitoye, T. Maclullich, A. M. J. Vardy, Erlc | Age Ageing | 2022 |
4 ‘A’s Test (4AT) |
| Barriers to completing the 4AT for delirium and its clinical implementation in two hospitals: a mixed-methods study | Alhaidari, A. A. O. Matsis, K. P. | Eur Geriatr Med | 2022 |
Aged |
| The quality of palliative sedation in end-stage disease: audit from a department of oncology and haematology | Alessia, S. Matilde, S. F. Chrystel, I. Massimiliano, S. Daniele, D. Claudia, F. Raffaella, P. Flavia, C. Leonardo, F. Chiara, C. Leonardo, P. Massimo, D. Mario, L. Giuseppe, L. | Support Care Cancer | 2022 |
Conscious Sedation/methods |
| Delirium risk in geriatric hip hemi-arthroplasty (DRIGHA): Development and validation of a novel score using a national data | Ahmed, N. Kuo, Y. H. | Injury | 2022 |
Aged |
| Postoperative delirium and its relationship with biomarkers for dementia: a meta-analysis | Wang, S. Greene, R. Song, Y. Chan, C. Lindroth, H. Khan, S. Rios, G. Sanders, R. D. Khan, B. | Int Psychogeriatr | 2022 |
Alzheimer’s disease |
| The association between midazolam premedication and postoperative delirium - a retrospective cohort study | Zarour, S. Weiss, Y. Kiselevich, Y. Iacubovici, L. Karol, D. Shaylor, R. Davydov, T. Matot, I. Cohen, B. | J Clin Anesth | 2023 |
Anesthesia, Elderly, Midazolam, Postoperative delirium |
| Effects of perioperative intravenous glucocorticoids on perioperative neurocognitive disorders in adults after surgery: A PRISMA-compliant meta-analysis of randomized controlled trials | Wang, F. Hao, X. Zhu, Y. | Medicine (Baltimore) | 2023 |
Humans, Adult, Adolescent, *Glucocorticoids, Randomized Controlled Trials as Topic, Administration, Intravenous, *Hip Fractures, Neurocognitive Disorders |
| Association between emergency department modifiable risk factors and subsequent delirium among hospitalized older adults | Oliveira, J. E. Silva L. Stanich, J. A. Jeffery, M. M. Lindroth, H. L. Miller, D. M. Campbell, R. L. Rabinstein, A. A. Pignolo, R. J. Bellolio, F. | Am J Emerg Med | 2022 |
Acute brain failure |
| Practices in sedation, analgesia, mobilization, delirium, and sleep deprivation in adult intensive care units (SAMDS-ICU): an international survey before and during the COVID-19 pandemic | Luz, M. Brandão Barreto, B. de Castro, R. E. V. Salluh, J. Dal-Pizzol, F. Araujo, C. De Jong, A. Chanques, G. Myatra, S. N. Tobar, E. Gimenez-Esparza Vich, C. Carini, F. Ely, E. W. Stollings, J. L. Drumright, K. Kress, J. Povoa, P. Shehabi, Y. Mphandi, W | Ann Intensive Care | 2022 |
Analgesia |
| Mental capacity legislation and communication disability: A cross-sectional survey exploring the impact of the COVID-19 pandemic on the provision of specialist decision-making support by UK SLTs | Jayes, M. Borrett, S. Bose, A. | Int J Lang Commun Disord | 2022 |
Adult |
| Delirium and Associated Factors in a Cohort of Hospitalized Patients With Coronavirus Disease 2019 | García-Grimshaw, M. Chiquete, E. Jiménez-Ruiz, A. Vidal-Mayo, J. J. Grajeda-González, S. L. Vargas-Martínez, MlÁ Toapanta-Yanchapaxi, L. N. Valdés-Ferrer, S. I. Chávez-Martínez, O. A. Marché-Fernández, O. A. Jiménez-Ávila, A. I. Cantú-Brito, | J Acad Consult Liaison Psychiatry | 2022 |
Adult |
| Inpatient Diagnosis of Delirium and Encephalopathy: Coding Trends in 2011-2018 | Franks, J. A. Anderson, J. L. Bowman, E. Li, C. Y. Kennedy, R. E. Yun, H. | J Acad Consult Liaison Psychiatry | 2022 |
Dsm |
| Effectiveness of combined non-pharmacological interventions in the prevention of delirium in critically ill patients: A randomized clinical trial | Faustino, T. N. Suzart, N. A. Rabelo, Rnds Santos, J. L. Batista, G. S. Freitas, Y. S. Saback, D. A. Sales, Nmmd Brandao Barreto, B. Gusmao-Flores, D. | J Crit Care | 2022 |
Critical Care |
| Combined cerebral and somatic near-infrared spectroscopy oximetry monitoring during liver surgery: an observational and non-interventional study | Collin, Y. Hu, T. Denault, A. Fortier, A. Beaubien-Souligny, W. Lapointe, R. Vandenbroucke-Menu, F. | Korean J Anesthesiol | 2022 |
Hepatectomy |
| Characteristics and Outcome Determinants of Hospitalized Older Patients with Cognitive Dysfunction | Chao, Y. T. Kuo, F. H. Lee, Y. S. Huang, Y. H. Weng, S. C. Chou, Y. Y. Lin, C. S. Lin, S. Y. | Int J Environ Res Public Health | 2022 |
Activities of Daily Living |
| Delirium in hospitalized patients with COVID-19 pneumonia: a prospective, cross-sectional, cohort study | Callea, A. Conti, G. Fossati, B. Carassale, L. Zagaria, M. Caporotundo, S. Ziglioli, E. Brunetti, V. Della Marca, G. Rollo, E. | Intern Emerg Med | 2022 |
Covid-19 |
| Association of perioperative midazolam use and complications: a population-based analysis | Athanassoglou, V. Cozowicz, C. Zhong, H. Illescas, A. Poeran, J. Liu, J. Poultsides, L. Memtsoudis, S. G. | Reg Anesth Pain Med | 2022 |
analgesia |
| Best practices to prevent delirium in hospitalised patients | Yerra, S. Yarra, P. | Evid Based Nurs | 2022 |
*Delirium/prevention & control |
| Inhalational Versus Propofol-based Intravenous Maintenance of Anesthesia for Emergence Delirium in Adults: A Meta-analysis and Trial Sequential Analysis | Yang, Y. Feng, L. Ji, C. Lu, K. Chen, Y. Chen, B. | J Neurosurg Anesthesiol | 2022 | |
| Role of interleukin-18 in postoperative delirium: an exploratory analysis | Wu, J. G. Taylor, J. Parker, M. Kunkel, D. Rivera, C. Pearce, R. A. Lennertz, R. Sanders, R. D. | Br J Anaesth | 2022 |
delirium |
| Effect of general anesthesia with thoracic paravertebral block on postoperative delirium in elderly patients undergoing thoracoscopic lobectomy: a randomized-controlled trial | Wei, W. Zheng, X. Gu, Y. Fu, W. Tang, C. Yao, Y. | BMC Anesthesiol | 2022 |
*Postoperative delirium |
| Probable Delirium and Associated Patient Characteristics in Long-Term Care and Complex Continuing Care: A Population-Based Observational Study | Webber, C. Watt, C. L. Bush, S. H. Lawlor, P. G. Knoefel, F. Momoli, F. Thavorn, K. Casey, G. Tanuseputro, P. | J Am Med Dir Assoc | 2022 |
Cross-Sectional Studies |
| Postoperative delirium and its relationship with biomarkers for dementia: a meta-analysis | Wang, S. Greene, R. Song, Y. Chan, C. Lindroth, H. Khan, S. Rios, G. Sanders, R. D. Khan, B. | Int Psychogeriatr | 2022 |
Alzheimer’s disease |
| Melatonin and melatonergic agents for the prevention of postoperative delirium: A meta-analysis of randomized placebo-controlled trials | Wang, C. M. Zhou, L. Y. | Asian J Surg | 2022 |
Adult |
| Dexmedetomidine for prevention of postoperative delirium in older adults undergoing oesophagectomy with total intravenous anaesthesia | Valent, A. Carval, A. Cattan, P. Plaud, B. | Eur J Anaesthesiol | 2022 |
Aged |
| Transfusion-Associated Delirium in Children: No Difference Between Short Storage Versus Standard Issue RBCs | Traube, C. Tucci, M. Nellis, M. E. Avery, K. L. McQuillen, P. S. Fitzgerald, J. C. Muszynski, J. A. Cholette, J. M. Schwarz, A. J. Stalets, E. L. Quaid, M. A. Hanson, S. J. Lacroix, J. Reeder, R. W. Spinella, P. C. | Crit Care Med | 2022 | |
| Pediatric Delirium: We Have Come a Long Way, and We Have Only Just Begun | Traube, C. | Crit Care Med | 2022 | |
| Beware the Aftermath: Delirium and Post-Intensive Care Syndrome in Critically Ill Children | Traube, C. | Pediatr Crit Care Med | 2022 | |
| Amyloid deposition on positron emission tomography correlates with severity of perioperative delirium: a case-control pilot study | Torres-Velázquez, M. Parker, M. Bo, A. White, M. Tanabe, S. Pearce, R. A. Lennertz, R. Cho, S. Y. Bendlin, B. Johnson, S. C. Prabhakaran, V. McMillan, A. B. Sanders, R. D. | Br J Anaesth | 2022 |
amyloid |
| VE-CAM-S: Visual EEG-Based Grading of Delirium Severity and Associations With Clinical Outcomes | Tesh, R. A. Sun, H. Jing, J. Westmeijer, M. Neelagiri, A. Rajan, S. Krishnamurthy, P. V. Sikka, P. Quadri, S. A. Leone, M. J. Paixao, L. Panneerselvam, E. Eckhardt, C. Struck, A. F. Kaplan, P. W. Akeju, O. Jones, D. Kimchi, E. Y. Westover, M. B. | Crit Care Explor | 2022 |
Eeg |
| KIBRA, MTNR1B, and FKBP5 genotypes are associated with decreased odds of incident delirium in elderly post-surgical patients | Terrelonge, M. LaHue, S. C. Tang, C. Movsesyan, I. Pullinger, C. R. Dubal, D. B. Leung, J. Douglas, V. C. | Sci Rep | 2022 | |
| Pilot Study of Lemborexant for Insomnia in Cancer Patients with Delirium | Terada, T. Hirayama, T. Sadahiro, R. Wada, S. Nakahara, R. Matsuoka, H. | J Palliat Med | 2022 |
cancer patients |
| Managing agitation secondary to hyperactive delirium in deteriorating patients | Teece, A. | Nurs Stand | 2022 |
*Delirium/etiology |
| Incidence of Delirium With Different Oral Opioids in Previously Opioid-Naive Patients | Sugiyama, Y. Tanaka, R. Sato, T. Sato, T. Saitoh, A. Yamada, D. Shino, M. | Am J Hosp Palliat Care | 2022 |
concomitant drugs |
| Adult behavior toward the child before surgery and pediatric emergence delirium | Sobol, M. Sobol, M. K. Kowal, M. | Paediatr Anaesth | 2022 |
Adult |
| Risk Factors for Delirium and Association of Antipsychotic Use with Delirium Progression in Critically Ill Trauma Patients | Shoulders, B. R. Elsabagh, S. Tam, D. J. Frantz, A. M. Alexander, K. M. Voils, S. A. | Am Surg | 2022 |
antipsychotic |
| Incidence and Risk Factors of Ventilator-Associated Pneumonia among Patients with Delirium in the Intensive Care Unit: A Prospective Observational Study | Shamsizadeh, M. Fathi Jouzdani, A. Rahimi-Bashar, F. | Crit Care Res Pract | 2022 | |
| Delirium in older adults, if you think it's the urine, think again | Schonnop, R. Woods, R. Ellis, B. | Cjem | 2022 | |
| The detection of delirium in admitted oncology patients: a scoping review | Sands, M. B. Wee, I. Agar, M. Vardy, J. L. | Eur Geriatr Med | 2022 |
Cancer |
| Delirium in the Context of Zonisamide-Induced Toxic Epidermal Necrolysis | Reinfeld, S. Tejeda, C. I. Koola, M. M. | Prim Care Companion CNS Disord | 2022 | |
| Prevalence of Delirium in End-of-life Palliative Care Patients: An Observational Study | Recchia, A. Rizzi, B. Favero, A. Nobili, A. Pasina, L. | Med Princ Pract | 2022 | |
| Hospitalizations of older people in an emergency department related to potential medication-induced hyperactive delirium: a cross-sectional study | Raso, J. Santos, L. M. C. Reis, D. A. Frangiotti, M. A. C. Zanetti, A. C. B. Capucho, H. C. Herdeiro, M. T. Roque, F. Pereira, L. R. L. Varallo, F. R. | Int J Clin Pharm | 2022 |
Aged |
| Clinical Significance of Delirium With Catatonic Signs in Patients With Neurological Disorders | Ramirez-Bermudez, J. Medina-Gutierrez, A. Gomez-Cianca, H. Arias, P. Pérez-Gonzalez, A. Lebrija-Reyes, P. A. Espinola-Nadurille, M. Aguilar-Venegas, L. C. Ojeda-López, C. Restrepo-Martínez, M. Bayliss, L. Juárez-Jaramillo, C. A. Peñaloza, G. Rivas-Al | J Neuropsychiatry Clin Neurosci | 2022 |
Catatonia |
| Patient perspectives on delirium and cognitive dysfunction after surgery: a cross-sectional survey | Ragheb, J. Khatibi, N. McKinney, A. Brooks, J. Hill-Carruthers, M. Vlisides, P. E. | Br J Anaesth | 2022 |
cognitive dysfunction |
| Association between delirium and cognitive impairment: there is a link? | Pistacchi, M. Gioulis, M. Marsala, S. Z. | Curr Alzheimer Res | 2022 |
Cognitive Impairment |
| Utility of white matter disease and atrophy on routinely acquired brain imaging for prediction of long-term delirium risk: population-based cohort study | Pendlebury, S. T. Thomson, R. J. Welch, S. J. V. Kuker, W. Rothwell, P. M. | Age Ageing | 2022 |
Atrophy/pathology |
| Massachusetts Intensive Care Unit Nurses From Multiple Hospitals Develop a Collaborative to Improve Delirium Assessment Accuracy | O'Donoghue, S. C. Meyers, K. Manning, C. R. Pellegrino, L. S. Ryan, C. P. Crowell, A. M. Nolan, L. M. Gallagher, G. E. | Dimens Crit Care Nurs | 2022 |
Critical Care |
| Incidence and factors associated with postoperative delirium in patients undergoing transurethral resection of bladder tumor | Nakatani, S. Ida, M. Wang, X. Naito, Y. Kawaguchi, M. | JA Clin Rep | 2022 |
Age |
| Association of Nutritional Status with New-Onset Delirium in Elderly, Acute Care, Orthopaedic Trauma Patients: A Single-Center Observational Study | Maher, S. S. Franco-Garcia, E. Zhou, C. Heng, M. van Pelt, M. Akeju, O. Quraishi, S. A. | J Orthop Trauma | 2022 |
Aged |
| Efficacy of EWINDOW for prevention of delirium at intensive care units: A protocol for systematic review and meta-analysis | Liu, J. Wang, J. | Medicine (Baltimore | 2022 |
delirium, EWINDOW, intensive care units |
| Delirium and subsyndromal delirium are associated with the long-term risk of death after ischaemic stroke | Klimiec-Moskal, E. Slowik, A. Dziedzic, T. | Aging Clin Exp Res | 2022 |
Delirium |
| An innovative post-hospital model of care (DDEFY Delirium): A pilot randomized trial | Khan, A. Uribe-Cano, D. Klumph, M. Simpson, M. Macias Tejada, J. Galambos, C. Hubatch, S. Malone, M. L. | J Am Geriatr Soc | 2022 | |
| Impact of postanesthesia care unit delirium on self-reported cognitive function and perceived health status: a prospective observational cohort study | Kainz, E. Stuff, K. Kahl, U. Wiessner, C. Yu, Y. von Breunig, F. Nitzschke, R. Haese, A. Graefen, M. Fischer, M. | Qual Life Res | 2022 |
Anesthesia recovery period |
| Can multifaceted educational intervention improve clinical practice and patient outcomes regarding delirium in nursing homes? | Jeong, E. Chang, S. O | Jpn J Nurs Sci | 2022 |
Aged |
| Does Preoperative Cognitive Optimization Improve Postoperative Outcomes in the Elderly? | Ishizawa, Y. | J Clin Med | 2022 |
advanced age |
| Postoperative Delirium in Lung Cancer Anatomical Resection-Analysis of Risk Factors and Prognosis | Ishibashi, H. Wakejima, R. Asakawa, A. Sugita, Y. Ishikawa, Y. Hanafusa, M. Baba, S. Nakashima, Y. Seto, K. Okubo, K. | World J Surg | 2022 | |
| Preoperative Risk Factors and Early Outcomes of Delirium in Valvular Open-Heart Surgery | Hulde, N. Zittermann, A. Tigges-Limmer, K. Koster, A. Weinrautner, N. Gummert, J. von Dossow, V. | Thorac Cardiovasc Surg | 2022 | |
| Plasma 5-HIAA activity indicative of serotonergic disturbances in cognitively impaired, elderly patients experiencing postoperative delirium | Heylen, A. Vermeiren, Y. De Rooij, S. E. Scholtens, R. M. Van Munster, B. C. Van Dam, D. De Deyn, P. P. | Int J Geriatr Psychiatry | 2022 |
Aged |
| Depression, Delirium and Post-Intensive Care Syndrome | Garcez-Leme, L. E. Avelino-Silva, T. J. | Int Psychogeriatr | 2022 | |
| Usefulness of Preoperative Controlling Nutritional Status in Predicting Prolonged Hospitalization and Incidence of Postoperative Delirium for Elderly Hepatectomy with Hepatocellular Carcinoma | Fujio, A. Usuda, M. Hara, Y. Kakizaki, Y. Okada, K. Miyata, G. Unno, M. Kamei, T. | Tohoku J Exp Med | 2022 |
Aged |
| Inpatient Diagnosis of Delirium and Encephalopathy: Coding Trends 2011-2018 | Franks, J. A. Anderson, J. L. Bowman, E. Li, C. Y. Kennedy, R. E. Yun, H. | J Acad Consult Liaison Psychiatry | 2022 |
Dsm |
| Barriers and facilitators to nursing delirium screening in older emergency patients: a qualitative study using the theoretical domains framework | Eagles, D. Cheung, W. J. Avlijas, T. Yadav, K. Ohle, R. Taljaard, M. Molnar, F. Stiell, I. G. | Age Ageing | 2022 |
Aged |
| The evidence for introducing case-finding for delirium and dementia in older medical inpatients in a New Zealand hospital | Cullum, S. Kubba, Y. Varghese, C. Coomarasamy, C. Hopkins, J. | Australas Psychiatry | 2022 |
case-finding |
| Pediatric delirium in times of COVID-19 | Castro, R. E. V. Rodríguez-Rubio, M. Magalhães-Barbosa, M. C. Prata-Barbosa, A. | Rev Bras Ter Intensiva | 2022 |
*covid-19 |
| Accuracy of delirium risk factors in adult intensive care unit patients | Carvalho, L. A. C. Correia, M. D. L. Ferreira, R. C. Botelho, M. L. Ribeiro, E. Duran, E. C. M. | Rev Esc Enferm USP | 2022 |
Adult |
| The management of delirium in the older adult in advanced nursing practice | Carey, E. Furlong, E. Smith, R. | Br J Nurs | 2022 |
*Advanced Practice Nursing |
| Postoperative Delirium: The Search for Effective Interventions | Campbell, D. Short, T. G. Chan, M. T. V. | J Neurosurg Anesthesiol | 2022 | |
| Confusion and Representative Restraint: An Exercise in Clinical Reasoning | Bushunow, V. Klein, A. Follansbee, W. Bonifacino, E. | J Gen Intern Med | 2022 |
*Clinical Reasoning |
| Psychoactive medication therapy and delirium screening in skilled nursing facilities | Briesacher, B. A. Olivieri-Mui, B. L. Koethe, B. Saczynski, J. S. Fick, D. M. Devlin, J. W. Marcantonio, E. R. | J Am Geriatr Soc | 2022 |
delirium |
| Comparison of delirium detection tools in acute care : A rapid review | Brefka, S. Eschweiler, G. W. Dallmeier, D. Denkinger, M. Leinert, C. | Z Gerontol Geriatr | 2022 |
4As test |
| Implications of the COVID-19 pandemic: Virtual nursing education for delirium care | Bourgault, A. Mayerson, E. Nai, M. Orsini-Garry, A. Alexander, I. M. | J Prof Nurs | 2022 |
*covid-19 |
| Postoperative delirium prediction using machine learning models and preoperative electronic health record data | Bishara, A. Chiu, C. Whitlock, E. L. Douglas, V. C. Lee, S. Butte, A. J. Leung, J. M. Donovan, A. L. | BMC Anesthesiol | 2022 |
*Delirium prevention |
| Association between nonpharmacological strategies and delirium in intensive care unit | Bersaneti, M. D. R. Whitaker, I. Y. | Nurs Crit Care | 2022 |
caregivers |
| Differential Effects of Gamma-Aminobutyric Acidergic Sedatives on Risk of Post-Extubation Delirium in the ICU: A Retrospective Cohort Study From a New England Health Care Network | Azimaraghi, O. Wongtangman, K. Wachtendorf, L. J. Santer, P. Rumyantsev, S. Ahn, C. Kiyatkin, M. E. Teja, B. Sarge, T. Subramaniam, B. Eikermann, M. | Crit Care Med | 2022 |
Differential Effects Gamma-Aminobutyric Acidergic Sedatives Risk Post-Extubation Delirium ICU Retrospective Cohort Study |
| Risk factors for postoperative delirium after cardiac surgical procedures with cardioplegic arrest | Andrási, T. B. Talipov, I. Dinges, G. Arndt, C. Rastan, A. J. | Eur J Cardiothorac Surg | 2022 |
Cabg |
| Delirium screening tools in the post-anaesthetic care unit: a systematic review and meta-analysis | Aldwikat, R. K. Manias, E. Tomlinson, E. Amin, M. Nicholson, P. | Aging Clin Exp Res | 2022 |
Delirium |
| Effect of earplug/eye mask on sleep and delirium in intensive care patients | Akpinar, R. B. Aksoy, M. Kant, E. | Nurs Crit Care | 2022 |
delirium |
| Inclusion of interleukin-6 improved performance of postoperative delirium prediction for patients undergoing coronary artery bypass graft (POD-CABG): A derivation and validation study | Zhang, S. Ji, M. H. Ding, S. Wu, Y. Feng, X. W. Tao, X. J. Liu, W. W. Ma, R. Y. Wu, F. Q. Chen, Y. L. | J Cardiol | 2021 |
Coronary artery bypass graft surgery |
| DNA methylation in the TNF-alpha gene decreases along with aging among delirium inpatients | Yamanashi, T. Saito, T. Yu, T. Alario, A. Comp, K. Crutchley, K. J. Sullivan, E. J. Anderson, Z. M. Marra, P. S. Chang, G. Wahba, N. E. Jellison, S. S. Meyer, A. A. Mathur, S. Pandharipande, P. Yoshino, A. Kaneko, K. Lee, S. Toda, H. Iwata, M. Shinozaki, | Neurobiol Aging | 2021 |
Aged |