What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Neuroleptic strategies for terminal agitation in patients with cancer and delirium at an acute palliative care unit: a single-centre, double-blind, parallel-group, randomised trial
- Authors
- Hui, D. De La Rosa, A. Wilson, A. Nguyen, T. Wu, J. Delgado-Guay, M. Azhar, A. Arthur, J. Epner, D. Haider, A. De La Cruz, M. Heung, Y. Tanco, K. Dalal, S. Reddy, A. Williams, J. Amin, S. Armstrong, T. S. Breitbart, W. Bruera, E.
- Year
- 2020
- Journal
- Lancet Oncol
- Abstract
BACKGROUND: The role of neuroleptics for terminal agitated delirium is controversial. We assessed the effect of three neuroleptic strategies on refractory agitation in patients with cancer with terminal delirium. METHODS: In this single-centre, double-blind, parallel-group, randomised trial, patients with advanced cancer, aged at least 18 years, admitted to the palliative and supportive care unit at the University of Texas MD Anderson Cancer Center (Houston, TX, USA), with refractory agitation, despite low-dose haloperidol, were randomly assigned to receive intravenous haloperidol dose escalation at 2 mg every 4 h, neuroleptic rotation with chlorpromazine at 25 mg every 4 h, or combined haloperidol at 1 mg and chlorpromazine at 12·5 mg every 4 h, until death or discharge. Rescue doses identical to the scheduled doses were administered at inception, and then hourly as needed. Permuted block randomisation (block size six; 1:1:1) was done, stratified by baseline Richmond Agitation Sedation Scale (RASS) scores. Research staff, clinicians, patients, and caregivers were masked to group assignment. The primary outcome was change in RASS score from time 0 to 24 h. Comparisons among group were done by modified intention-to-treat analysis. This completed study is registered with ClinicalTrials.gov, NCT03021486. FINDINGS: Between July 5, 2017, and July 1, 2019, 998 patients were screened for eligibility, with 68 being enrolled and randomly assigned to treatment; 45 received the masked study interventions (escalation n=15, rotation n=16, combination n=14). RASS score decreased significantly within 30 min and remained low at 24 h in the escalation group (n=10, mean RASS score change between 0 h and 24 h -3·6 [95% CI -5·0 to -2·2]), rotation group (n=11, -3·3 [-4·4 to -2·2]), and combination group (n=10, -3·0 [-4·6 to -1·4]), with no difference among groups (p=0·71). The most common serious toxicity was hypotension (escalation n=6 [40%], rotation n=5 [31%], combination n=3 [21%]); there were no treatment-related deaths. INTERPRETATION: Our data provide preliminary evidence that the three strategies of neuroleptics might reduce agitation in patients with terminal agitation. These findings are in the context of the single-centre design, small sample size, and lack of a placebo-only group. FUNDING: National Institute of Nursing Research.
- PMID
- Keywords
Aged
Antipsychotic Agents/ therapeutic use
Delirium/ drug therapy/etiology/pathology
Double-Blind Method
Female
Follow-Up Studies
Haloperidol/ therapeutic use
Humans
Male
Middle Aged
Neoplasms/ complications/psychology/therapy
Palliative Care
Prognosis
Psychomotor Agitation/ drug therapy/etiology/pathology
- Page(s)
- 989-998
- Volume
- 21
- Issue
- 7
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| Brain Network Dysfunction in Poststroke Delirium and Spatial Neglect: An fMRI Study | Boukrina, O. Kowalczyk, M. Koush, Y. Kong, Y. Barrett, A. M. | Stroke | 2022 |
Adult |
| Postoperative delirium prediction using machine learning models and preoperative electronic health record data | Bishara, A. Chiu, C. Whitlock, E. L. Douglas, V. C. Lee, S. Butte, A. J. Leung, J. M. Donovan, A. L. | BMC Anesthesiol | 2022 |
Aged |
| High-dose preoperative glucocorticoid for prevention of emergence and postoperative delirium in liver resection: A double-blinded randomized clinical trial substudy | Awada, H. N. Steinthorsdottir, K. J. Schultz, N. A. Hillingsø, J. G. Larsen, P. N. Jans, Ø Kehlet, H. Aasvang, E. K. | Acta Anaesthesiol Scand | 2022 |
emergence |
| Grip strength as a predictor of postoperative delirium in patients with colorectal cancers | Arita, A. Takahashi, H. Ogino, T. Miyoshi, N. Uemura, M. Akasaka, H. Sugimoto, K. Rakugi, H. Doki, Y. Eguchi, H. | Ann Gastroenterol Surg | 2022 |
colorectal cancer |
| Positive scores on the 4AT delirium assessment tool at hospital admission are linked to mortality, length of stay and home time: two-centre study of 82,770 emergency admissions | Anand, A. Cheng, M. Ibitoye, T. Maclullich, A. M. J. Vardy, Erlc | Age Ageing | 2022 |
4 ‘A’s Test (4AT) |
| Barriers to completing the 4AT for delirium and its clinical implementation in two hospitals: a mixed-methods study | Alhaidari, A. A. O. Matsis, K. P. | Eur Geriatr Med | 2022 |
Aged |
| The quality of palliative sedation in end-stage disease: audit from a department of oncology and haematology | Alessia, S. Matilde, S. F. Chrystel, I. Massimiliano, S. Daniele, D. Claudia, F. Raffaella, P. Flavia, C. Leonardo, F. Chiara, C. Leonardo, P. Massimo, D. Mario, L. Giuseppe, L. | Support Care Cancer | 2022 |
Conscious Sedation/methods |
| Delirium risk in geriatric hip hemi-arthroplasty (DRIGHA): Development and validation of a novel score using a national data | Ahmed, N. Kuo, Y. H. | Injury | 2022 |
Aged |
| Postoperative delirium and its relationship with biomarkers for dementia: a meta-analysis | Wang, S. Greene, R. Song, Y. Chan, C. Lindroth, H. Khan, S. Rios, G. Sanders, R. D. Khan, B. | Int Psychogeriatr | 2022 |
Alzheimer’s disease |
| The association between midazolam premedication and postoperative delirium - a retrospective cohort study | Zarour, S. Weiss, Y. Kiselevich, Y. Iacubovici, L. Karol, D. Shaylor, R. Davydov, T. Matot, I. Cohen, B. | J Clin Anesth | 2023 |
Anesthesia, Elderly, Midazolam, Postoperative delirium |
| Effects of perioperative intravenous glucocorticoids on perioperative neurocognitive disorders in adults after surgery: A PRISMA-compliant meta-analysis of randomized controlled trials | Wang, F. Hao, X. Zhu, Y. | Medicine (Baltimore) | 2023 |
Humans, Adult, Adolescent, *Glucocorticoids, Randomized Controlled Trials as Topic, Administration, Intravenous, *Hip Fractures, Neurocognitive Disorders |
| Association between emergency department modifiable risk factors and subsequent delirium among hospitalized older adults | Oliveira, J. E. Silva L. Stanich, J. A. Jeffery, M. M. Lindroth, H. L. Miller, D. M. Campbell, R. L. Rabinstein, A. A. Pignolo, R. J. Bellolio, F. | Am J Emerg Med | 2022 |
Acute brain failure |
| Practices in sedation, analgesia, mobilization, delirium, and sleep deprivation in adult intensive care units (SAMDS-ICU): an international survey before and during the COVID-19 pandemic | Luz, M. Brandão Barreto, B. de Castro, R. E. V. Salluh, J. Dal-Pizzol, F. Araujo, C. De Jong, A. Chanques, G. Myatra, S. N. Tobar, E. Gimenez-Esparza Vich, C. Carini, F. Ely, E. W. Stollings, J. L. Drumright, K. Kress, J. Povoa, P. Shehabi, Y. Mphandi, W | Ann Intensive Care | 2022 |
Analgesia |
| Mental capacity legislation and communication disability: A cross-sectional survey exploring the impact of the COVID-19 pandemic on the provision of specialist decision-making support by UK SLTs | Jayes, M. Borrett, S. Bose, A. | Int J Lang Commun Disord | 2022 |
Adult |
| Delirium and Associated Factors in a Cohort of Hospitalized Patients With Coronavirus Disease 2019 | García-Grimshaw, M. Chiquete, E. Jiménez-Ruiz, A. Vidal-Mayo, J. J. Grajeda-González, S. L. Vargas-Martínez, MlÁ Toapanta-Yanchapaxi, L. N. Valdés-Ferrer, S. I. Chávez-Martínez, O. A. Marché-Fernández, O. A. Jiménez-Ávila, A. I. Cantú-Brito, | J Acad Consult Liaison Psychiatry | 2022 |
Adult |
| Inpatient Diagnosis of Delirium and Encephalopathy: Coding Trends in 2011-2018 | Franks, J. A. Anderson, J. L. Bowman, E. Li, C. Y. Kennedy, R. E. Yun, H. | J Acad Consult Liaison Psychiatry | 2022 |
Dsm |
| Effectiveness of combined non-pharmacological interventions in the prevention of delirium in critically ill patients: A randomized clinical trial | Faustino, T. N. Suzart, N. A. Rabelo, Rnds Santos, J. L. Batista, G. S. Freitas, Y. S. Saback, D. A. Sales, Nmmd Brandao Barreto, B. Gusmao-Flores, D. | J Crit Care | 2022 |
Critical Care |
| Combined cerebral and somatic near-infrared spectroscopy oximetry monitoring during liver surgery: an observational and non-interventional study | Collin, Y. Hu, T. Denault, A. Fortier, A. Beaubien-Souligny, W. Lapointe, R. Vandenbroucke-Menu, F. | Korean J Anesthesiol | 2022 |
Hepatectomy |
| Characteristics and Outcome Determinants of Hospitalized Older Patients with Cognitive Dysfunction | Chao, Y. T. Kuo, F. H. Lee, Y. S. Huang, Y. H. Weng, S. C. Chou, Y. Y. Lin, C. S. Lin, S. Y. | Int J Environ Res Public Health | 2022 |
Activities of Daily Living |
| Delirium in hospitalized patients with COVID-19 pneumonia: a prospective, cross-sectional, cohort study | Callea, A. Conti, G. Fossati, B. Carassale, L. Zagaria, M. Caporotundo, S. Ziglioli, E. Brunetti, V. Della Marca, G. Rollo, E. | Intern Emerg Med | 2022 |
Covid-19 |
| Association of perioperative midazolam use and complications: a population-based analysis | Athanassoglou, V. Cozowicz, C. Zhong, H. Illescas, A. Poeran, J. Liu, J. Poultsides, L. Memtsoudis, S. G. | Reg Anesth Pain Med | 2022 |
analgesia |
| Best practices to prevent delirium in hospitalised patients | Yerra, S. Yarra, P. | Evid Based Nurs | 2022 |
*Delirium/prevention & control |
| Inhalational Versus Propofol-based Intravenous Maintenance of Anesthesia for Emergence Delirium in Adults: A Meta-analysis and Trial Sequential Analysis | Yang, Y. Feng, L. Ji, C. Lu, K. Chen, Y. Chen, B. | J Neurosurg Anesthesiol | 2022 | |
| Role of interleukin-18 in postoperative delirium: an exploratory analysis | Wu, J. G. Taylor, J. Parker, M. Kunkel, D. Rivera, C. Pearce, R. A. Lennertz, R. Sanders, R. D. | Br J Anaesth | 2022 |
delirium |
| Effect of general anesthesia with thoracic paravertebral block on postoperative delirium in elderly patients undergoing thoracoscopic lobectomy: a randomized-controlled trial | Wei, W. Zheng, X. Gu, Y. Fu, W. Tang, C. Yao, Y. | BMC Anesthesiol | 2022 |
*Postoperative delirium |
| Probable Delirium and Associated Patient Characteristics in Long-Term Care and Complex Continuing Care: A Population-Based Observational Study | Webber, C. Watt, C. L. Bush, S. H. Lawlor, P. G. Knoefel, F. Momoli, F. Thavorn, K. Casey, G. Tanuseputro, P. | J Am Med Dir Assoc | 2022 |
Cross-Sectional Studies |
| Postoperative delirium and its relationship with biomarkers for dementia: a meta-analysis | Wang, S. Greene, R. Song, Y. Chan, C. Lindroth, H. Khan, S. Rios, G. Sanders, R. D. Khan, B. | Int Psychogeriatr | 2022 |
Alzheimer’s disease |
| Melatonin and melatonergic agents for the prevention of postoperative delirium: A meta-analysis of randomized placebo-controlled trials | Wang, C. M. Zhou, L. Y. | Asian J Surg | 2022 |
Adult |
| Dexmedetomidine for prevention of postoperative delirium in older adults undergoing oesophagectomy with total intravenous anaesthesia | Valent, A. Carval, A. Cattan, P. Plaud, B. | Eur J Anaesthesiol | 2022 |
Aged |
| Transfusion-Associated Delirium in Children: No Difference Between Short Storage Versus Standard Issue RBCs | Traube, C. Tucci, M. Nellis, M. E. Avery, K. L. McQuillen, P. S. Fitzgerald, J. C. Muszynski, J. A. Cholette, J. M. Schwarz, A. J. Stalets, E. L. Quaid, M. A. Hanson, S. J. Lacroix, J. Reeder, R. W. Spinella, P. C. | Crit Care Med | 2022 | |
| Pediatric Delirium: We Have Come a Long Way, and We Have Only Just Begun | Traube, C. | Crit Care Med | 2022 | |
| Beware the Aftermath: Delirium and Post-Intensive Care Syndrome in Critically Ill Children | Traube, C. | Pediatr Crit Care Med | 2022 | |
| Amyloid deposition on positron emission tomography correlates with severity of perioperative delirium: a case-control pilot study | Torres-Velázquez, M. Parker, M. Bo, A. White, M. Tanabe, S. Pearce, R. A. Lennertz, R. Cho, S. Y. Bendlin, B. Johnson, S. C. Prabhakaran, V. McMillan, A. B. Sanders, R. D. | Br J Anaesth | 2022 |
amyloid |
| VE-CAM-S: Visual EEG-Based Grading of Delirium Severity and Associations With Clinical Outcomes | Tesh, R. A. Sun, H. Jing, J. Westmeijer, M. Neelagiri, A. Rajan, S. Krishnamurthy, P. V. Sikka, P. Quadri, S. A. Leone, M. J. Paixao, L. Panneerselvam, E. Eckhardt, C. Struck, A. F. Kaplan, P. W. Akeju, O. Jones, D. Kimchi, E. Y. Westover, M. B. | Crit Care Explor | 2022 |
Eeg |
| KIBRA, MTNR1B, and FKBP5 genotypes are associated with decreased odds of incident delirium in elderly post-surgical patients | Terrelonge, M. LaHue, S. C. Tang, C. Movsesyan, I. Pullinger, C. R. Dubal, D. B. Leung, J. Douglas, V. C. | Sci Rep | 2022 | |
| Pilot Study of Lemborexant for Insomnia in Cancer Patients with Delirium | Terada, T. Hirayama, T. Sadahiro, R. Wada, S. Nakahara, R. Matsuoka, H. | J Palliat Med | 2022 |
cancer patients |
| Managing agitation secondary to hyperactive delirium in deteriorating patients | Teece, A. | Nurs Stand | 2022 |
*Delirium/etiology |
| Incidence of Delirium With Different Oral Opioids in Previously Opioid-Naive Patients | Sugiyama, Y. Tanaka, R. Sato, T. Sato, T. Saitoh, A. Yamada, D. Shino, M. | Am J Hosp Palliat Care | 2022 |
concomitant drugs |
| Adult behavior toward the child before surgery and pediatric emergence delirium | Sobol, M. Sobol, M. K. Kowal, M. | Paediatr Anaesth | 2022 |
Adult |
| Risk Factors for Delirium and Association of Antipsychotic Use with Delirium Progression in Critically Ill Trauma Patients | Shoulders, B. R. Elsabagh, S. Tam, D. J. Frantz, A. M. Alexander, K. M. Voils, S. A. | Am Surg | 2022 |
antipsychotic |
| Incidence and Risk Factors of Ventilator-Associated Pneumonia among Patients with Delirium in the Intensive Care Unit: A Prospective Observational Study | Shamsizadeh, M. Fathi Jouzdani, A. Rahimi-Bashar, F. | Crit Care Res Pract | 2022 | |
| Delirium in older adults, if you think it's the urine, think again | Schonnop, R. Woods, R. Ellis, B. | Cjem | 2022 | |
| The detection of delirium in admitted oncology patients: a scoping review | Sands, M. B. Wee, I. Agar, M. Vardy, J. L. | Eur Geriatr Med | 2022 |
Cancer |
| Delirium in the Context of Zonisamide-Induced Toxic Epidermal Necrolysis | Reinfeld, S. Tejeda, C. I. Koola, M. M. | Prim Care Companion CNS Disord | 2022 | |
| Prevalence of Delirium in End-of-life Palliative Care Patients: An Observational Study | Recchia, A. Rizzi, B. Favero, A. Nobili, A. Pasina, L. | Med Princ Pract | 2022 | |
| Hospitalizations of older people in an emergency department related to potential medication-induced hyperactive delirium: a cross-sectional study | Raso, J. Santos, L. M. C. Reis, D. A. Frangiotti, M. A. C. Zanetti, A. C. B. Capucho, H. C. Herdeiro, M. T. Roque, F. Pereira, L. R. L. Varallo, F. R. | Int J Clin Pharm | 2022 |
Aged |
| Clinical Significance of Delirium With Catatonic Signs in Patients With Neurological Disorders | Ramirez-Bermudez, J. Medina-Gutierrez, A. Gomez-Cianca, H. Arias, P. Pérez-Gonzalez, A. Lebrija-Reyes, P. A. Espinola-Nadurille, M. Aguilar-Venegas, L. C. Ojeda-López, C. Restrepo-Martínez, M. Bayliss, L. Juárez-Jaramillo, C. A. Peñaloza, G. Rivas-Al | J Neuropsychiatry Clin Neurosci | 2022 |
Catatonia |
| Patient perspectives on delirium and cognitive dysfunction after surgery: a cross-sectional survey | Ragheb, J. Khatibi, N. McKinney, A. Brooks, J. Hill-Carruthers, M. Vlisides, P. E. | Br J Anaesth | 2022 |
cognitive dysfunction |
| Association between delirium and cognitive impairment: there is a link? | Pistacchi, M. Gioulis, M. Marsala, S. Z. | Curr Alzheimer Res | 2022 |
Cognitive Impairment |
| Utility of white matter disease and atrophy on routinely acquired brain imaging for prediction of long-term delirium risk: population-based cohort study | Pendlebury, S. T. Thomson, R. J. Welch, S. J. V. Kuker, W. Rothwell, P. M. | Age Ageing | 2022 |
Atrophy/pathology |
| Massachusetts Intensive Care Unit Nurses From Multiple Hospitals Develop a Collaborative to Improve Delirium Assessment Accuracy | O'Donoghue, S. C. Meyers, K. Manning, C. R. Pellegrino, L. S. Ryan, C. P. Crowell, A. M. Nolan, L. M. Gallagher, G. E. | Dimens Crit Care Nurs | 2022 |
Critical Care |
| Incidence and factors associated with postoperative delirium in patients undergoing transurethral resection of bladder tumor | Nakatani, S. Ida, M. Wang, X. Naito, Y. Kawaguchi, M. | JA Clin Rep | 2022 |
Age |
| Association of Nutritional Status with New-Onset Delirium in Elderly, Acute Care, Orthopaedic Trauma Patients: A Single-Center Observational Study | Maher, S. S. Franco-Garcia, E. Zhou, C. Heng, M. van Pelt, M. Akeju, O. Quraishi, S. A. | J Orthop Trauma | 2022 |
Aged |
| Efficacy of EWINDOW for prevention of delirium at intensive care units: A protocol for systematic review and meta-analysis | Liu, J. Wang, J. | Medicine (Baltimore | 2022 |
delirium, EWINDOW, intensive care units |
| Delirium and subsyndromal delirium are associated with the long-term risk of death after ischaemic stroke | Klimiec-Moskal, E. Slowik, A. Dziedzic, T. | Aging Clin Exp Res | 2022 |
Delirium |
| An innovative post-hospital model of care (DDEFY Delirium): A pilot randomized trial | Khan, A. Uribe-Cano, D. Klumph, M. Simpson, M. Macias Tejada, J. Galambos, C. Hubatch, S. Malone, M. L. | J Am Geriatr Soc | 2022 | |
| Impact of postanesthesia care unit delirium on self-reported cognitive function and perceived health status: a prospective observational cohort study | Kainz, E. Stuff, K. Kahl, U. Wiessner, C. Yu, Y. von Breunig, F. Nitzschke, R. Haese, A. Graefen, M. Fischer, M. | Qual Life Res | 2022 |
Anesthesia recovery period |
| Can multifaceted educational intervention improve clinical practice and patient outcomes regarding delirium in nursing homes? | Jeong, E. Chang, S. O | Jpn J Nurs Sci | 2022 |
Aged |
| Does Preoperative Cognitive Optimization Improve Postoperative Outcomes in the Elderly? | Ishizawa, Y. | J Clin Med | 2022 |
advanced age |
| Postoperative Delirium in Lung Cancer Anatomical Resection-Analysis of Risk Factors and Prognosis | Ishibashi, H. Wakejima, R. Asakawa, A. Sugita, Y. Ishikawa, Y. Hanafusa, M. Baba, S. Nakashima, Y. Seto, K. Okubo, K. | World J Surg | 2022 | |
| Preoperative Risk Factors and Early Outcomes of Delirium in Valvular Open-Heart Surgery | Hulde, N. Zittermann, A. Tigges-Limmer, K. Koster, A. Weinrautner, N. Gummert, J. von Dossow, V. | Thorac Cardiovasc Surg | 2022 | |
| Plasma 5-HIAA activity indicative of serotonergic disturbances in cognitively impaired, elderly patients experiencing postoperative delirium | Heylen, A. Vermeiren, Y. De Rooij, S. E. Scholtens, R. M. Van Munster, B. C. Van Dam, D. De Deyn, P. P. | Int J Geriatr Psychiatry | 2022 |
Aged |
| Depression, Delirium and Post-Intensive Care Syndrome | Garcez-Leme, L. E. Avelino-Silva, T. J. | Int Psychogeriatr | 2022 | |
| Usefulness of Preoperative Controlling Nutritional Status in Predicting Prolonged Hospitalization and Incidence of Postoperative Delirium for Elderly Hepatectomy with Hepatocellular Carcinoma | Fujio, A. Usuda, M. Hara, Y. Kakizaki, Y. Okada, K. Miyata, G. Unno, M. Kamei, T. | Tohoku J Exp Med | 2022 |
Aged |
| Inpatient Diagnosis of Delirium and Encephalopathy: Coding Trends 2011-2018 | Franks, J. A. Anderson, J. L. Bowman, E. Li, C. Y. Kennedy, R. E. Yun, H. | J Acad Consult Liaison Psychiatry | 2022 |
Dsm |
| Barriers and facilitators to nursing delirium screening in older emergency patients: a qualitative study using the theoretical domains framework | Eagles, D. Cheung, W. J. Avlijas, T. Yadav, K. Ohle, R. Taljaard, M. Molnar, F. Stiell, I. G. | Age Ageing | 2022 |
Aged |
| The evidence for introducing case-finding for delirium and dementia in older medical inpatients in a New Zealand hospital | Cullum, S. Kubba, Y. Varghese, C. Coomarasamy, C. Hopkins, J. | Australas Psychiatry | 2022 |
case-finding |
| Pediatric delirium in times of COVID-19 | Castro, R. E. V. Rodríguez-Rubio, M. Magalhães-Barbosa, M. C. Prata-Barbosa, A. | Rev Bras Ter Intensiva | 2022 |
*covid-19 |
| Accuracy of delirium risk factors in adult intensive care unit patients | Carvalho, L. A. C. Correia, M. D. L. Ferreira, R. C. Botelho, M. L. Ribeiro, E. Duran, E. C. M. | Rev Esc Enferm USP | 2022 |
Adult |
| The management of delirium in the older adult in advanced nursing practice | Carey, E. Furlong, E. Smith, R. | Br J Nurs | 2022 |
*Advanced Practice Nursing |
| Postoperative Delirium: The Search for Effective Interventions | Campbell, D. Short, T. G. Chan, M. T. V. | J Neurosurg Anesthesiol | 2022 | |
| Confusion and Representative Restraint: An Exercise in Clinical Reasoning | Bushunow, V. Klein, A. Follansbee, W. Bonifacino, E. | J Gen Intern Med | 2022 |
*Clinical Reasoning |
| Psychoactive medication therapy and delirium screening in skilled nursing facilities | Briesacher, B. A. Olivieri-Mui, B. L. Koethe, B. Saczynski, J. S. Fick, D. M. Devlin, J. W. Marcantonio, E. R. | J Am Geriatr Soc | 2022 |
delirium |
| Comparison of delirium detection tools in acute care : A rapid review | Brefka, S. Eschweiler, G. W. Dallmeier, D. Denkinger, M. Leinert, C. | Z Gerontol Geriatr | 2022 |
4As test |
| Implications of the COVID-19 pandemic: Virtual nursing education for delirium care | Bourgault, A. Mayerson, E. Nai, M. Orsini-Garry, A. Alexander, I. M. | J Prof Nurs | 2022 |
*covid-19 |
| Postoperative delirium prediction using machine learning models and preoperative electronic health record data | Bishara, A. Chiu, C. Whitlock, E. L. Douglas, V. C. Lee, S. Butte, A. J. Leung, J. M. Donovan, A. L. | BMC Anesthesiol | 2022 |
*Delirium prevention |
| Association between nonpharmacological strategies and delirium in intensive care unit | Bersaneti, M. D. R. Whitaker, I. Y. | Nurs Crit Care | 2022 |
caregivers |
| Differential Effects of Gamma-Aminobutyric Acidergic Sedatives on Risk of Post-Extubation Delirium in the ICU: A Retrospective Cohort Study From a New England Health Care Network | Azimaraghi, O. Wongtangman, K. Wachtendorf, L. J. Santer, P. Rumyantsev, S. Ahn, C. Kiyatkin, M. E. Teja, B. Sarge, T. Subramaniam, B. Eikermann, M. | Crit Care Med | 2022 |
Differential Effects Gamma-Aminobutyric Acidergic Sedatives Risk Post-Extubation Delirium ICU Retrospective Cohort Study |
| Risk factors for postoperative delirium after cardiac surgical procedures with cardioplegic arrest | Andrási, T. B. Talipov, I. Dinges, G. Arndt, C. Rastan, A. J. | Eur J Cardiothorac Surg | 2022 |
Cabg |
| Delirium screening tools in the post-anaesthetic care unit: a systematic review and meta-analysis | Aldwikat, R. K. Manias, E. Tomlinson, E. Amin, M. Nicholson, P. | Aging Clin Exp Res | 2022 |
Delirium |
| Effect of earplug/eye mask on sleep and delirium in intensive care patients | Akpinar, R. B. Aksoy, M. Kant, E. | Nurs Crit Care | 2022 |
delirium |
| Inclusion of interleukin-6 improved performance of postoperative delirium prediction for patients undergoing coronary artery bypass graft (POD-CABG): A derivation and validation study | Zhang, S. Ji, M. H. Ding, S. Wu, Y. Feng, X. W. Tao, X. J. Liu, W. W. Ma, R. Y. Wu, F. Q. Chen, Y. L. | J Cardiol | 2021 |
Coronary artery bypass graft surgery |
| DNA methylation in the TNF-alpha gene decreases along with aging among delirium inpatients | Yamanashi, T. Saito, T. Yu, T. Alario, A. Comp, K. Crutchley, K. J. Sullivan, E. J. Anderson, Z. M. Marra, P. S. Chang, G. Wahba, N. E. Jellison, S. S. Meyer, A. A. Mathur, S. Pandharipande, P. Yoshino, A. Kaneko, K. Lee, S. Toda, H. Iwata, M. Shinozaki, | Neurobiol Aging | 2021 |
Aged |
| DNA methylation in the inflammatory genes after neurosurgery and diagnostic ability of post-operative delirium | Yamanashi, T. Nagao, T. Wahba, N. E. Marra, P. S. Crutchley, K. J. Meyer, A. A. Andreasen, A. J. Hellman, M. M. Jellison, S. S. Hughes, C. G. Pandharipande, P. P. Howard Iii, M. A. Kawasaki, H. Iwata, M. Hefti, M. M. Shinozaki, G. | Transl Psychiatry | 2021 |
Epigenetics and behaviour, Molecular neuroscience |
| Intraoperative hypotension and delirium among older adults undergoing transcatheter aortic valve replacement | Wesselink, E. M. Abawi, M. Kooistra, N. H. M. Kappen, T. H. Agostoni, P. Emmelot-Vonk, M. Pasma, W. van Klei, W. A. van Jaarsveld, R. C. van Dongen, C. S. Doevendans, Pafm Slooter, A. J. C. Stella, P. R. | J Am Geriatr Soc | 2021 |
Aged, 80 and over |
| Patterns of Delirium in a Pediatric Intensive Care Unit and Associations With Noise Pollution | Weatherhead, J. R. Niedner, M. Dahmer, M. K. Malas, N. Owens, T. Kawai, Y. | J Intensive Care Med | 2021 |
delirium |
| Gender Differences and Postoperative Delirium in Adult Patients Undergoing Cardiac Valve Surgery | Wang, H. Guo, X. Zhu, X. Li, Y. Jia, Y. Zhang, Z. Yuan, S. Yan, F. | Front Cardiovasc Med | 2021 |
adult |
| Comparison of restrictive fluid therapy with goal-directed fluid therapy for postoperative delirium in patients undergoing spine surgery: a randomized controlled trial | Wang, D. D. Li, Y. Hu, X. W. Zhang, M. C. Xu, X. M. Tang, J. | Perioper Med (Lond) | 2021 |
Goal-directed fluid therapy |
| Effect of dexmedetomidine on postoperative delirium in patients undergoing brain tumour resections: study protocol of a randomised controlled trial | Wang, D. Li, R. Li, S. Wang, J. Zeng, M. Dong, J. Liu, X. Lin, N. Peng, Y. | BMJ Open | 2021 |
*Brain Neoplasms |
| Association of preoperative frailty with postoperative delirium after elective brain tumor resection: Retrospective analysis of a prospective cohort | Wang, C. M. Ma, Y. L. Yang, X. Y. Ji, R. Q. Gu, W. J. Zhou, J. X. | Surgery | 2021 |
Adult |
| Delirium and other neuropsychiatric manifestations of COVID-19 infection in people with preexisting psychiatric disorders: a systematic review | van Reekum, E. A. Rosic, T. Sergeant, A. Sanger, N. Rodrigues, M. Rebinsky, R. Panesar, B. Deck, E. Kim, N. Woo, J. D'Elia, A. Hillmer, A. Dufort, A. Sanger, S. Thabane, L. Mbuagbaw, L. Samaan, Z. | J Med Case Rep | 2021 |
Bias |
| Suvorexant with or without ramelteon to prevent delirium: a systematic review and meta-analysis | Tian, Y. Qin, Z. Han, Y. | Psychogeriatrics | 2021 |
delirium |
| Nurses' Experience of Caring for Patients with Delirium: Systematic Review and Qualitative Evidence Synthesis | Thomas, N. Coleman, M. Terry, D. | Nurs Rep | 2021 |
anxiety |
| Understanding the decision-making of critical care nurses when restraining a patient with psychomotor agitation secondary to hyperactive delirium: A 'Think Aloud' study | Teece, A. Baker, J. Smith, H | J Clin Nurs | 2022 |
Critical Care |
| Reduced Electroencephalogram Complexity in Postoperative Delirium | Tanabe, S. Parker, M. Lennertz, R. Pearce, R. A. Banks, M. I. Sanders, R. D. | J Gerontol A Biol Sci Med Sci | 2021 |
*Age-related pathology |
| Using Telehealth to Improve the Accuracy of Delirium Screening by Bedside Critical Care Nurses | Sinvani, L. Hertz, C. Chandra, S. Ilyas, A. Ardito, S. Hajizadeh, N. | Am J Crit Care | 2022 | |
| Melatonin for prevention of postoperative delirium after lower limb fracture surgery in elderly patients (DELIRLESS): study protocol for a multicentre randomised controlled trial | Sigaut, S. Couffignal, C. Esposito-Farèse, M. Degos, V. Molliex, S. Boddaert, J. Raynaud-Simon, A. Durand-Zaleski, I. Marcault, E. Jacota, M. Dahmani, S. Paugam-Burtz, C. Weiss, E. | BMJ Open | 2021 |
anaesthesia in orthopaedics |
| Management of delirium in a medical and surgical intensive care unit | Shivji, S. Stabler, S. N. Boyce, K. Haljan, G. J. McGloin, R. | J Clin Pharm Ther | 2021 |
Aged |
| 5-HT(3) receptor antagonists decrease the prevalence of postoperative delirium in older patients undergoing orthopedic lower limb surgery | Shin, H. J. Yoon, J. Na, H. S. | Perioper Med (Lond) | 2021 |
5-HT3 receptor antagonist |
| Neutrophil-Lymphocyte Ratio as a Potential Biomarker for Delirium in the Intensive Care Unit | Seo, C. L. Park, J. Y. Park, J. Kim, H. E. Cho, J. Seok, J. H. Kim, J. J. Shin, C. S. Oh, J. | Front Psychiatry | 2021 |
C-reactive protein |