What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Preoperative Depression and Plasma Cortisol Levels as Predictors of Delirium after Cardiac Surgery
- Authors
- Eshmawey, M. Arlt, S. Ledschbor-Frahnert, C. Guenther, U. Popp, J.
- Year
- 2020
- Journal
- Dementia and Geriatric Cognitive Disorders
- Abstract
Background: Delirium is common in old patients who undergo cardiac surgery, and it is associated with adverse outcomes. The genesis of delirium is thought to be multi-factorial, but it is still not well understood. Symptoms of depression and elevated cortisol level have been described in some previous studies as factors associated with delirium, suggesting a shared pathophysiology. Aims: The objective of the present study was to determine whether preoperative depression symptoms and increased cortisol level represent risk factors for delirium after cardiac surgery. Methods: We performed a prospective cohort study in 183 patients aged >50 years undergoing elective cardiac surgery. The Geriatric Depression Scale (GDS) was used to assess patients for depressive symptoms before surgery. Preoperative plasma cortisol levels were available in 145 participants. Delirium was diagnosed using the Confusion Assessment Method for Intensive Care Unit (CAM-ICU) during the first 7 days after surgery. Spearman correlation was used for correlations between GDS, Mini-Mental State Examination (MMSE), Charlson comorbidity index, and age. Binary logistic regression was used to determine whether GDS and cortisol levels predict postoperative delirium. Results: Delirium occurred in 60 patients out of 183 (32.8%) included and lasted 2.3 days (SD 1.36). GDS was correlated with age (p = 0.001) and comorbidity index (p = 0.003) and inversely correlated with MMSE score (p < 0.001). Higher preoperative GDS scores were associated with incidence of delirium in the postoperative period (p = 0.002). The association was significant after controlling for age, MMSE score, history of stroke, and Charlson comorbidity index (p = 0.045). Preoperative cortisol level was not associated with the development of postoperative delirium. Conclusion: Our results suggest that a higher preoperative depression score is associated with an increased risk of postoperative delirium. On the other hand, preoperative plasma cortisol level does not seem to be a predictor of delirium after surgery. Further studies are needed to determine the potential of preoperative depression treatment to prevent postoperative delirium.
- PMID
- Keywords
hydrocortisone
aged
article
cerebrovascular accident
Charlson Comorbidity Index
cohort analysis
comorbidity
controlled study
depression
disease duration
elective surgery
female
Geriatric Depression Scale
heart surgery
human
hydrocortisone blood level
major clinical study
male
medical history
Mini Mental State Examination
postoperative delirium
preoperative period
priority journal
prospective study
risk factor
- Page(s)
- 207-214
- Volume
- 48
- Issue
- 3-4
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| Impact of propofol versus sevoflurane on the incidence of postoperative delirium in elderly patients after spine surgery: study protocol of a randomized controlled trial | Wang, J. H. Lv, M. Zhang, H. X. Gao, Y. Chen, T. T. Wan, T. T. Wang, Y. L. | Trials | 2022 |
Aged |
| Impact of propofol versus sevoflurane on the incidence of postoperative delirium in elderly patients after spine surgery: study protocol of a randomized controlled trial | Wang, J. H. Lv, M. Zhang, H. X. Gao, Y. Chen, T. T. Wan, T. T. Wang, Y. L. | Trials | 2022 |
Aged |
| Potential Value of Serum Uric Acid in the Identification of Postoperative Delirium in Geriatric Patients Undergoing Knee Replacement | Wang, F. Tang, X. Wang, J. Liu, S. Wu, X. Dong, R. Lin, X. Wang, B. Bi, Y. | Front Aging Neurosci | 2022 |
Alzheimer-related biomarkers |
| Patient Outcomes After Delirium Screening and Incident Alzheimer's Disease or Related Dementias in Skilled Nursing Facilities | Vo, Q. T. Koethe, B. Holmes, S. Simoni-Wastila, L. Briesacher, B. A. | J Gen Intern Med | 2022 |
Alzheimer’s disease |
| Delirium in head trauma: looking for a culprit | Villani, E. R. Franza, L. Cianci, R. | Rev Recent Clin Trials | 2022 |
Delirium |
| Timing, Threshold, and Duration of Intraoperative Hypotension in Cardiac Surgery: Their Associations With Postoperative Delirium | Ushio, M. Egi, M. Fujimoto, D. Obata, N. Mizobuchi, S. | J Cardiothorac Vasc Anesth | 2022 |
Cardiac valvular surgery |
| Detecting delirium in nursing home residents using the Informant Assessment of Geriatric Delirium (I-AGeD): a validation pilot study | Urfer Dettwiler, P. Zúñiga, F. Bachnick, S. Gehri, B. de Jonghe, J. F. M. Hasemann, W. | Eur Geriatr Med | 2022 |
Aged |
| Association of preoperative frailty and postoperative delirium in older cancer patients undergoing elective abdominal surgery: a prospective observational study in Taiwan | Tsai, C. Y. Liu, K. H. Lai, C. C. Hsu, J. T. Hsueh, S. W. Hung, C. Y. Yeh, K. Y. Hung, Y. S. Lin, Y. C. Chou, W. C. | Biomed J | 2022 |
cancer |
| Delirium and Cortical Complexity: Divergent Changes in Alpha and Theta Bands | Tanabe, S. Parker, M. Lennertz, R. Pearce, R. A. Banks, M. I. Sanders, R. D. | J Gerontol A Biol Sci Med Sci | 2022 | |
| Escaping delirium: Designing an escape room active learning experience for geriatric resource nurses | Stoller, A. Iannuzzo, S. Davis, K. | Geriatr Nurs | 2022 |
Creative problem solving |
| Perivascular spaces visible on magnetic resonance imaging predict subsequent delirium in older patients | Song, Q. Zhao, Y. Lin, T. Yue, J. | Front Aging Neurosci | 2022 |
cerebral small vessel disease |
| Postoperative delirium does not affect cardiopulmonary exercise testing in aged patients undergoing cardiac valve surgery | Shimomoto, Y. Mukaiyama, K. Hori, T. Inaki, Y. Masai, T. Hayashi, Y. | JA Clin Rep | 2022 |
Cardiac rehabilitation |
| Silent cerebral ischemia detected by magnetic resonance imaging can predict postoperative delirium after total arch replacement for aneurysm | Shibagaki, K. Shirasaka, T. Sawada, J. Saijo, Y. Kunioka, S. Kikuchi, Y. Kamiya, H. | JTCVS Open | 2022 |
AAA, aortic arch aneurysm |
| Impact of delirium on the outcome of stroke: a prospective, observational, cohort study | Rollo, E. Brunetti, V. Scala, I. Callea, A. Marotta, J. Vollono, C. Frisullo, G. Broccolini, A. Calabresi, P. Della Marca, G. | J Neurol | 2022 |
Delirium |
| Association between non-English language and use of physical and chemical restraints among medical inpatients with delirium | Reppas-Rindlisbacher, C. Shin, S. Purohit, U. Verma, A. Razak, F. Rochon, P. Sheehan, K. Rawal, S. | J Am Geriatr Soc | 2022 | |
| Sedation, analgesia, and delirium management in Portugal: a survey and point prevalence study | Paulino, M. C. Pereira, I. J. Costa, V. Neves, A. Santos, A. Teixeira, C. M. Coimbra, I. Fernandes, P. Bernardo, R. Póvoa, P. Granja, C. | Rev Bras Ter Intensiva | 2022 |
*Analgesia |
| Acute kidney injury-associated delirium: a review of clinical and pathophysiological mechanisms | Pang, H. Kumar, S. Ely, E. W. Gezalian, M. M. Lahiri, S. | Crit Care | 2022 |
*Acute Kidney Injury |
| Delirium Development After Lung Transplantation: An Intraoperative Assessment | Ozay, H. Y. Bindal, M. Turkkan, S. Beyoglu, M. A. Yekeler, E. Turan, S. | Transplant Proc | 2022 | |
| Delirium severity does not differ between medical and surgical intensive care units after adjusting for medication use | Ortiz, D. Lindroth, H. L. Braly, T. Perkins, A. J. Mohanty, S. Meagher, A. D. Khan, S. H. Boustani, M. A. Khan, B. A. | Sci Rep | 2022 |
Activities of Daily Living |
| Risk factors for postoperative delirium on oxygen delivery-guided perfusion | Mukaida, H. Matsushita, S. Minami, Y. Sato, G. Usuba, M. Kondo, R. Asai, T. Amano, A. | J Cardiothorac Surg | 2022 |
Cardiopulmonary Bypass/adverse effects/methods |
| Identifying Medicare Beneficiaries With Delirium | Moura, Lmvr Zafar, S. Benson, N. M. Festa, N. Price, M. Donahue, M. A. Normand, S. L. Newhouse, J. P. Blacker, D. Hsu, J. | Med Care | 2022 | |
| The development of a web-based app employing machine learning for delirium prevention in long-term care facilities in South Korea | Moon, K. J. Son, C. S. Lee, J. H. Park, M. | BMC Med Inform Decis Mak | 2022 |
*Delirium/diagnosis/prevention & control |
| Impact of Family Presence on Delirium in Critically Ill Patients: A Retrospective Cohort Study | Mohsen, S. Moss, S. J. Lucini, F. Krewulak, K. D. Stelfox, H. T. Niven, D. J. Sauro, K. M. Fiest, K. M. | Crit Care Med | 2022 | |
| Serum levels of apolipoprotein A-I and E are associated with postoperative delirium: A post hoc analysis | Mietani, K. Hasegawa-Moriyama, M. Inoue, R. Ogata, T. Shimojo, N. Kurano, M. Yatomi, Y. Uchida, K. Sumitani, M. | Medicine (Baltimore) | 2022 |
Aged |
| Staff training and the use of rapid, accurate and user-friendly tools for delirium screening could improve the diagnosis of delirium in the elderly referred to the emergency department | Mazzola, P. Spedale, V. | Evid Based Nurs | 2022 |
evidence-based nursing |
| Current practice of pharmacological treatment for hyperactive delirium in terminally ill cancer patients: results of a nationwide survey of Japanese palliative care physicians and liaison psychiatrists | Matsuda, Y. Morita, T. Oya, K. Tagami, K. Naito, A. S. Kashiwagi, H. Otani, H. | Jpn J Clin Oncol | 2022 |
*Antipsychotic Agents/therapeutic use |
| Higher serum PGE2 is a predicative biomarker for postoperative delirium following elective orthopedic surgery in elderly patients | Mao, M. Wang, L. Y. Zhu, L. Y. Wang, F. Ding, Y. Tong, J. H. Sun, J. Sun, Q. Ji, M. H. | BMC Geriatr | 2022 |
Aged |
| Effect of acute pain on the association between preoperative cognitive impairment and postoperative delirium: a secondary analysis of three trials | Ma, J. H. Liu, Y. F. Hong, H. Li, C. J. Cui, F. Mu, D. L. Wang, D. X. | Br J Anaesth | 2022 |
cognitive dysfunction |
| A systematic review of modified electroconvulsive therapy (ECT) to treat delirium | Lupke, K. Warren, N. Teodorczuk, A. Steele, S. Kolur, U. Wand, A. Robinson, G. Parker, S. | Acta Psychiatr Scand | 2022 |
acute confusion |
| Incidence and interaction factors of delirium as an independent risk of mortality in elderly patients in the intensive units: a retrospective analysis from MIMIC-IV database | Liu, H. Zhao, Q. Liu, X. Hu, X. Wang, L. Zhou, F. | Aging Clin Exp Res | 2022 |
Delirium |
| The effect of neostigmine on postoperative delirium after colon carcinoma surgery: a randomized, double-blind, controlled trial | Liu, F. Lin, X. Lin, Y. Deng, X. Guo, Y. Wang, B. Dong, R. Bi, Y. | BMC Anesthesiol | 2022 |
Adult |
| Outcomes of postoperative delirium in patients undergoing cardiac surgery: A systematic review and meta-analysis | Lin, L. Zhang, X. Xu, S. Peng, Y. Li, S. Huang, X. Chen, L. Lin, Y. | Front Cardiovasc Med | 2022 |
cardiac surgery |
| Non-pharmacological delirium prevention practices among critical care nurses: a qualitative study | Liang, S. Chau, J. P. C. Lo, S. H. S. Zhao, J. Liu, W. | BMC Nurs | 2022 |
Delirium |
| Effect of regional anesthesia on the postoperative delirium: A systematic review and meta-analysis of randomized controlled trials | Li, T. Dong, T. Cui, Y. Meng, X. Dai, Z. | Front Surg | 2022 |
delirium |
| Assessing Delirium at Hospital Discharge | Lepkowsky, C. M. Janklow, H. M. | Am J Geriatr Psychiatry | 2022 |
Delirium |
| The Effects of Pain, Agitation, Delirium, Immobility, and Sleep Disruption Education on Novice Nurses in Adult Intensive Care Units | Lee, S. Y. Liu, C. Y. Wu, T. Y. | Healthcare (Basel) | 2022 |
Padis |
| Treatment of Positive Urine Cultures at End-of-Life and the Effect on Terminal Delirium Management | Latuga, N. M. Grant, P. C. Levy, K. Luczkiewicz, D. L. | Am J Hosp Palliat Care | 2022 |
Anti-Bacterial Agents/therapeutic use |
| Risk factors and effect of postoperative delirium on adverse surgical outcomes in older adults after elective abdominal cancer surgery in Taiwan | Lai, C. C. Liu, K. H. Tsai, C. Y. Hsu, J. T. Hsueh, S. W. Hung, C. Y. Chou, W. C. | Asian J Surg | 2022 |
Cancer surgery |
| A Quality Improvement Study on Delirium Awareness Day: In Pursuit of Missed Delirium Diagnoses | Koca, M. Öztürk, Y. Boğa, İ Bürkük, S. Eşme, M. Akyürek, Y. Şimşek, S. Aydın, D. D. Çiçek, F. Karabulut, E. Halil, M. Cankurtaran, M. Tanrıöver, M. D. Doğu, B. B. | J Gerontol Nurs | 2022 |
Aged |
| Serum C-reactive protein adds predictive information for post-stroke delirium: The PROPOLIS study | Klimiec-Moskal, E. Slowik, A. Dziedzic, T. | Acta Psychiatr Scand | 2022 |
Crp |
| External validation and comparison of two delirium prediction models in patients admitted to the cardiac intensive care unit | Kim, S. E. Ko, R. E. Na, S. J. Chung, C. R. Choi, K. H. Kim, D. Park, T. K. Lee, J. M. Song, Y. B. Choi, J. O. Hahn, J. Y. Choi, S. H. Gwon, H. C. Yang, J. H. | Front Cardiovasc Med | 2022 |
Early PREdiction of DELIRium |
| Delirium and Cortical Complexity | Kim, H. Lee, U. C. Vlisides, P. E. | Delirium and Cortical Complexity | 2022 | |
| Can Variables From the Electronic Health Record Identify Delirium at Bedside? | Khan, A. Heslin, K. Simpson, M. Malone, M. L. | J Patient Cent Res Rev | 2022 |
delirium |
| Thoracic Paravertebral Block Ameliorates Postoperative Delirium in Geriatric Patients | Heng, L. Wang, M. Wang, M. Li, L. Zhu, S. | Thorac Cardiovasc Surg | 2022 |
Aged |
| Relationship of sleep disturbance and postoperative delirium: a systematic review and meta-analysis | He, E. Dong, Y. Jia, H. Yu, L. | Gland Surg | 2022 |
Postoperative delirium (PD) |
| Acceptability of transdermal antipsychotic patches by patients who refuse oral medication and their effectiveness in preventing recurrence of delirium: a retrospective observational study | Hatta, K. Usui, C. Nakamura, H. | Int Clin Psychopharmacol | 2022 | |
| Perioperative Hemodynamic Optimization in Patients at Risk for Delirium - A Randomized-Controlled Trial | Fuest, K. E. Servatius, A. Ulm, B. Schaller, S. J. Jungwirth, B. Blobner, M. Schmid, S. | Front Med (Lausanne) | 2022 |
frailty |
| Proposing a Scientific and Technological Approach to the Summaries of Clinical Issues of Inpatient Elderly with Delirium: A Viewpoint | Frisardi, V. Nicolini, M. Cautero, N. Ghirardelli, R. Davolio, F. Haouili, M. Barani, M. | Healthcare (Basel) | 2022 |
delirium |
| Incidence of Drug-Induced Delirium During Treatment With Antidepressants or Antipsychotics: A Drug Surveillance Report of German-Speaking Countries Between 1993 and 2016 | Friedrich, M. E. Grohmann, R. Rabl, U. Winkler, D. Konstantinidis, A. Engel, R. Seifert, J. Toto, S. Stübner, S. Frey, R. Kasper, S. | Int J Neuropsychopharmacol | 2022 |
Adverse Drug Reaction Reporting Systems |
| The inter-relationship between delirium and dementia: the importance of delirium prevention | Fong, T. G. Inouye, S. K. | Nat Rev Neurol | 2022 | |
| Five-Year Outcomes After Implementing a Pain, Agitation, and Delirium Protocol in a Mixed Intensive Care Unit | Fish, J. T. Baxa, J. T. Draheim, R. R. Willenborg, M. J. Mills, J. C. Sticht, L. A. Hankwitz, J. L. Wells, J. A. Jung, H. S. | J Intensive Care Med | 2022 |
Adult |
| Improving Delirium Assessments in Vanderbilt Pediatric and Pediatric Cardiovascular Intensive Care Units | Eken, H. N. Betters, K. A. Fuchs, D. C. Smith, H. A. B. Williams, S. R. | Pediatr Qual Saf | 2022 | |
| Outcomes in Post-operative Delirium Following Bowel Resection: A Single Center Retrospective Review | Desrochers, R. M. Lynch, L. J. Gates, J. D. Ricaurte, D. Wade, J. T. Dicks, R. S. Keating, J. J. | J Surg Res | 2022 |
Bowel |
| Efficacy and Safety of Remimazolam Besylate versus Dexmedetomidine for Sedation in Non-Intubated Older Patients with Agitated Delirium After Orthopedic Surgery: A Randomized Controlled Trial | Deng, Y. Qin, Z. Wu, Q. Liu, L. Yang, X. Ju, X. Zhang, Y. Liu, L. | Drug Des Devel Ther | 2022 |
Benzodiazepines |
| Delirium, changes in cognitive function, and risk of diagnosed dementia after kidney transplantation | Chu, N. M. Bae, S. Chen, X. Ruck, J. Gross, A. L. Albert, M. Neufeld, K. J. Segev, D. L. McAdams-DeMarco, M. A. | Am J Transplant | 2022 |
clinical research/practice |
| Bispectral Index (BIS) Monitoring and Postoperative Delirium in Elderly Patients Undergoing Surgery: A Systematic Review and Meta-Analysis With Trial Sequential Analysis | Chew, W. Z. Teoh, W. Y. Sivanesan, N. Loh, P. S. Shariffuddin,, II Ti, L. K. Ng, K. T. | J Cardiothorac Vasc Anesth | 2022 |
Bis |
| Delirium prevalence in geriatric emergency department patients: A systematic review and meta-analysis | Chen, F. Liu, L. Wang, Y. Liu, Y. Fan, L. Chi, J. | Am J Emerg Med | 2022 |
Aged |
| Improving quantification of anticholinergic burden using the Anticholinergic Effect on Cognition Scale - a healthcare improvement study in a geriatric ward setting | Balasundaram, B. Ang, W. S. T. Stewart, R. Bishara, D. Ooi, C. H. Li, F. Akram, F. Eu Kwek, A. B. | Australas Psychiatry | 2022 |
Aged |
| The Association of Selective Serotonin Reuptake Inhibitors With Delirium in Critically Ill Adults: A Secondary Analysis of the Bringing to Light the Risk Factors and Incidence of Neuropsychologic Dysfunction in ICU Survivors ICU Study | Austin, C. A. Yi, J. Lin, F. C. Pandharipande, P. Ely, E. W. Busby-Whitehead, J. Carson, S. S. | Crit Care Explor | 2022 |
delirium |
| Parental Education and Delirium Risk after Surgery in Older Adults | Arias, F. Chen, F. Shiff, H. Marcantonio, E. R. Jones, R. N. Schmitt, E. M. Metzger, E. Fong, T. G. Travison, T. G. Inouye, S. K. | Clin Gerontol | 2022 |
Childhood socioeconomic status |
| Informing the standardising of care for prolonged stay patients in the ICU: A scoping review of quality improvement tools | Allum, L. Apps, C. Pattison, N. Connolly, B. Rose, L. | Intensive Crit Care Nurs | 2022 |
Bundle |
| Monitoring of nighttime EEG slow-wave activity during dexmedetomidine infusion in patients with hyperactive ICU delirium: An observational pilot study | Ala-Kokko, T. Erikson, K. Koskenkari, J. Laurila, J. Kortelainen, J. | Acta Anaesthesiol Scand | 2022 |
C-trend |
| Development of a Delirium Risk Predication Model among ICU Patients in Oman | Al-Hoodar, R. K. Lazarus, E. R. Alomari, O. Alzaabi, O. | Anesthesiol Res Pract | 2022 | |
| Comparison Between Deltascan Single Channel Electroencephalography (EEG), Confusion Assessment Method-Intensive Care Unit (CAM-ICU) Score and Clinical Assessment in Diagnosing Delirium in Intubated Patients in the Intensive Care Unit | Aben, J. Pouwels, S. Oldenbeuving, A. | Cureus | 2022 |
cam-icu |
| A Cross-Sectional Survey on the Clinical Management of Emergence Delirium in Adults: Knowledge, Attitudes, and Practice in Mainland China | Yuan, Y. Lei, B. Li, Z. Wang, X. Zhao, H. Gao, M. Xue, Y. Zhang, W. Xiao, R. Meng, X. Zheng, H. Zhang, J. Wang, G. Guo, X. | Brain Sci | 2022 |
Pacu |
| Development and Validation of a Nomogram for Predicting Postoperative Delirium in Patients With Elderly Hip Fracture Based on Data Collected on Admission | Yang, Y. Wang, T. Guo, H. Sun, Y. Cao, J. Xu, P. Cai, Y. | Front Aging Neurosci | 2022 |
albumin |
| Preoperative Inflammatory Markers and the Risk of Postoperative Delirium in Patients Undergoing Lumbar Spinal Fusion Surgery | Yang, J. S. Lee, J. J. Kwon, Y. S. Kim, J. H. Sohn, J. H. | J Clin Med | 2022 |
CRP-to-albumin ratio |
| An association between cancer type and delirium incidence in Japanese elderly patients: A retrospective longitudinal study | Yamato, K. Ikeda, A. Endo, M. Filomeno, R. Kiyohara, K. Inada, K. Nishimura, K. Tanigawa, T. | Cancer Med | 2022 |
cancer |
| Increased Direct Current-Electroencephalography Shifts During Induction of Anesthesia in Elderly Patients Developing Postoperative Delirium | Windmann, V. Dreier, J. P. Major, S. Spies, C. Lachmann, G. Koch, S. | Front Aging Neurosci | 2022 |
*dc-eeg |
| Risk factors of delirium after gastrointestinal surgery: A meta-analysis | Wang, X. Yu, D. Du, Y. Geng, J. | J Clin Nurs | 2022 |
delirium |
| Physician Experience Design (PXD): More Usable Machine Learning Prediction for Clinical Decision Making | Wang, L. Chignell, M. Zhang, Y. Pinto, A. Razak, F. Sheehan, K. Verma, A. | AMIA Annu Symp Proc | 2022 |
Artificial Intelligence |
| The Relationship Between Cardiovascular Disease Risk Score and Postoperative Delirium: The PNDABLE Study | Wang, J. Wang, L. Tang, X. Wang, F. Liu, S. Wu, X. Dong, R. Lin, X. Wang, B. Bi, Y. | Front Aging Neurosci | 2022 |
biomarkers |
| Preoperative intervention to prevent delirium in patients with hip fracture - a systematic review | Virsøe-Frandsen, C. D. Skjold, C. Wildgaard, K. Møller, A. M. | Dan Med J | 2022 |
Aged |
| Coexisting delirium and excited catatonia | Vellanki, K. D. Carroll, B. T. | Ann Clin Psychiatry | 2022 |
*Antipsychotic Agents/therapeutic use |
| Confusion regarding the use of Natural Language Processing in ICU delirium assessment | van Diem-Zaal, I. J. van den Boogaard, M. Kotfis, K. Ely, E. W. | Intensive Care Med | 2022 |
*Delirium/diagnosis |
| Postoperative delirium and changes in the blood-brain barrier, neuroinflammation, and cerebrospinal fluid lactate: a prospective cohort study | Taylor, J. Parker, M. Casey, C. P. Tanabe, S. Kunkel, D. Rivera, C. Zetterberg, H. Blennow, K. Pearce, R. A. Lennertz, R. C. Sanders, R. D. | Br J Anaesth | 2022 |
Biomarkers |
| Prospective clinical intervention study of aripiprazole and risperidone in the management of postoperative delirium in elderly patients after cardiovascular surgery | Sugawara, H. Koyama, A. Maruyama, T. Koda, Y. Fukunaga, H. Ishikawa, T. Takebayashi, M. Okamoto, K. Fukui, T. Hashimoto, M. | Psychiatry Clin Neurosci | 2022 | |
| A simple risk score list can be used to predict the occurrence of delirium in patients admitted to inpatient hospice care: A medical record study | Stoevelaar, R. Juffermans, C. C. M. Roorda, I. M. M. de Nijs, E. J. M. Hoornweg, J. Cannegieter, S. C. van der Linden, Y. M. | Eur J Cancer Care (Engl) | 2022 |
delirium |
| Chemokines in ICU Delirium: An Exploratory Study | Smith, R. J. Rabinstein, A. A. Cartin-Ceba, R. Singh, V. P. Lachner, C. Khatua, B. Trivedi, S. Gajic, O. | Crit Care Explor | 2022 |
chemokine |
| Cytokine profiles in intensive care unit delirium | Smith, R. J. Lachner, C. Singh, V. P. Trivedi, S. Khatua, B. Cartin-Ceba, R. | Acute Crit Care | 2022 |
cytokine |
| Edmonton frailty scale score predicts postoperative delirium: a retrospective cohort analysis | Sieber, F. Gearhart, S. Bettick, D. Wang, N. Y | BMC Geriatr | 2022 |
Cohort Studies |
| Observation of Anesthetic Effect of Dexmedetomidine Combined With Intraspinal Anesthesia in Hip Arthroplasty and its Effect on Postoperative Delirium and Stress Response | Shen, Y. Wang, C. Zhong, X. Wu, Y. He, X. | Front Surg | 2022 |
anesthetic effects |
| Postoperative Application of Dexmedetomidine is the Optimal Strategy to Reduce the Incidence of Postoperative Delirium After Cardiac Surgery: A Network Meta-Analysis of Randomized Controlled Trials | Shang, L. Hou, M. Guo, F. | Ann Pharmacother | 2022 |
cardiac surgery |
| Decreasing delirium through music listening (DDM) in critically ill, mechanically ventilated older adults in the intensive care unit: a two-arm, parallel-group, randomized clinical trial | Seyffert, S. Moiz, S. Coghlan, M. Balozian, P. Nasser, J. Rached, E. A. Jamil, Y. Naqvi, K. Rawlings, L. Perkins, A. J. Gao, S. Hunter, J. D., 3rd Khan, S. Heiderscheit, A. Chlan, L. L. Khan, B. | Trials | 2022 |
Aged |
| Prevention of delirium with agitation by yokukansan in older adults after cancer surgery | Sadahiro, R. Wada, S. Matsuoka, Y. J. Uchitomi, Y. Yamaguchi, T. Sato, T. Esaki, M. Yoshimoto, S. Daiko, H. Kanemitsu, Y. Kawai, A. Kato, T. Fujimoto, H. Uezono, Y. Shimizu, K. Matsuoka, H. | Jpn J Clin Oncol | 2022 |
clinical trial |
| Midazolam impacts acetyl-And butyrylcholinesterase genes: An epigenetic explanation for postoperative delirium? | Rump, K. Holtkamp, C. Bergmann, L. Nowak, H. Unterberg, M. Orlowski, J. Thon, P. Bazzi, Z. Bazzi, M. Adamzik, M. Koos, B. Rahmel, T. | PLoS One | 2022 |
Acetylcholinesterase/metabolism |
| Ren, X. Zhang, S. Yang, Y. Song, A. Liang, F. Zhang, Y. Dong, Y. Wu, X. Xie, Z. | Ketamine Induces Delirium-Like Behavior and Interferes With Endosomal Tau Trafficking | Anesth Analg | 2022 | |
| The crucial factors influencing the development and outcomes of postoperative delirium in proximal femur fractures | Rajeev, A. Railton, C. Devalia, K. | Aging Med (Milton) | 2022 |
delirium |
| Neuromonitoring depth of anesthesia and its association with postoperative delirium | Pérez-Otal, B. Aragón-Benedí, C. Pascual-Bellosta, A. Ortega-Lucea, S. Martínez-Ubieto, J. Ramírez-Rodríguez, J. M. | Sci Rep | 2022 |
Anesthesia, General/adverse effects |
| Improving the Detection, Assessment, Management and Prevention of Delirium in Hospices (the DAMPen-D study): protocol for a co-design and feasibility study of a flexible and scalable implementation strategy to deliver guideline-adherent delirium care | Pearson, M. Jackson, G. Jackson, C. Boland, J. Featherstone, I. Huang, C. Ogden, M. Sartain, K. Siddiqi, N. Twiddy, M. Johnson, M. | BMJ Open | 2022 |
*Delirium/diagnosis/prevention & control |
| An Interdisciplinary Reappraisal of Delirium and Proposed Subtypes | Oldham, M. A. Slooter, A. J. C. Ely, E. W. Crone, C. Maldonado, J. R. Rosenthal, L. J. | J Acad Consult Liaison Psychiatry | 2022 |
acute encephalopathy |
| Postoperative Delirium in Patients with Oral Cancer: Is Intraoperative Fluid Administration a Neglected Risk Factor? | Obermeier, K. T. Kraus, M. Smolka, W. Henkel, J. Saller, T. Otto, S. Liokatis, P. | Cancers (Basel) | 2022 |
fluid balance |
| Risk of delirium associated with antimuscarinics in older adults: A case-time-control study | Nishtala, P. S. Chyou, T. Y. | Pharmacoepidemiol Drug Saf | 2022 |
Aged |
| Potential effects of regular use of antihypertensive drugs for in-hospital delirium in geriatric patients with trauma | Nagasawa, H. Omori, K. Ota, S. Muramatsu, K. I. Ishikawa, K. Yanagawa, Y. | Sci Rep | 2022 |
Aged |
| Performance of Melatonin as Prophylaxis in Geriatric Patients with Multifactorial Risk for Postoperative Delirium Development: A Randomized Comparative Study | Mohamed, S. A. Rady, A. Youssry, M. Abdelaziz Mohamed, M. R. Gamal, M. | Turk J Anaesthesiol Reanim | 2022 | |
| Perioperative risk factors associated with increased incidence of postoperative delirium: systematic review, meta-analysis, and Grading of Recommendations Assessment, Development, and Evaluation system report of clinical literature | Mevorach, L. Forookhi, A. Farcomeni, A. Romagnoli, S. Bilotta, F. | Br J Anaesth | 2022 |
Grade |
| Delirium in ICU Patients after Cardiac Arrest: A Scoping Review | Mędrzycka-Dąbrowska, W. Lange, S. Religa, D. Dąbrowski, S. Friganović, A. Oomen, B. Krupa, S. | J Pers Med | 2022 |
Icu |
| Epidemiology of delirium in hospitalized patients in Latin America: A systematic review | Maximiliano, B. Sebastian, B. Estefania, A. Irma, C. Gutierrez, P. Daniela, P. Pv Roberta, C. Eduardo, T. Jose, M. Felipe, S. | Acta Psychiatr Scand | 2022 |
Latin America |
| Effect of Perioperative Dexmedetomidine Infusion on Postoperative Delirium in Elderly Patients Undergoing Oral and Maxillofacial Surgery: A Randomized Controlled Clinical Trial | Liu, T. Tuo, J. Wei, Q. Sun, X. Zhao, H. Zhao, X. Qu, M. | Int J Gen Med | 2022 |
dexmedetomidine |
| Type 2 Diabetes Mellitus with Tight Glucose Control and Poor Pre-Injury Stair Climbing Capacity May Predict Postoperative Delirium: A Secondary Analysis | Liu, K. Song, Y. Yuan, Y. Li, Z. Wang, X. Zhang, W. Li, Y. Mi, X. Han, D. Rong, Y. Guo, X. Wang, G. | Brain Sci | 2022 |
glycemic control |