What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Exercise for acutely hospitalised older medical patients
- Authors
- Hartley, P. Keating, J. L. Jeffs, K. J. Raymond, M. J. Smith, T. O
- Year
- 2022
- Journal
- Cochrane Database Syst Rev
- Abstract
BACKGROUND: Approximately 30% of hospitalised older adults experience hospital-associated functional decline. Exercise interventions that promote in-hospital activity may prevent deconditioning and thereby maintain physical function during hospitalisation. This is an update of a Cochrane Review first published in 2007. OBJECTIVES: To evaluate the benefits and harms of exercise interventions for acutely hospitalised older medical inpatients on functional ability, quality of life (QoL), participant global assessment of success and adverse events compared to usual care or a sham-control intervention. SEARCH METHODS: We used standard, extensive Cochrane search methods. The latest search date was May 2021. SELECTION CRITERIA: We included randomised or quasi-randomised controlled trials evaluating an in-hospital exercise intervention in people aged 65 years or older admitted to hospital with a general medical condition. We excluded people admitted for elective reasons or surgery. DATA COLLECTION AND ANALYSIS: We used standard Cochrane methods. Our major outcomes were 1. independence with activities of daily living; 2. functional mobility; 3. new incidence of delirium during hospitalisation; 4. QoL; 5. number of falls during hospitalisation; 6. medical deterioration during hospitalisation and 7. participant global assessment of success. Our minor outcomes were 8. death during hospitalisation; 9. musculoskeletal injuries during hospitalisation; 10. hospital length of stay; 11. new institutionalisation at hospital discharge; 12. hospital readmission and 13. walking performance. We used GRADE to assess certainty of evidence for each major outcome. We categorised exercise interventions as: rehabilitation-related activities (interventions designed to increase physical activity or functional recovery, but did not follow a specified exercise protocol); structured exercise (interventions that included an exercise intervention protocol but did not include progressive resistance training); and progressive resistance exercise (interventions that included an element of progressive resistance training). MAIN RESULTS: We included 24 studies (nine rehabilitation-related activity interventions, six structured exercise interventions and nine progressive resistance exercise interventions) with 7511 participants. All studies compared exercise interventions to usual care; two studies, in addition to usual care, used sham interventions. Mean ages ranged from 73 to 88 years, and 58% of participants were women. Several studies were at high risk of bias. The most common domain assessed at high risk of bias was measurement of the outcome, and five studies (21%) were at high risk of bias arising from the randomisation process. Exercise may have no clinically important effect on independence in activities of daily living at discharge from hospital compared to controls (16 studies, 5174 participants; low-certainty evidence). Five studies used the Barthel Index (scale: 0 to 100, higher scores representing greater independence). Mean scores at discharge in the control groups ranged from 42 to 96 points, and independence in activities of daily living was 1.8 points better (0.43 worse to 4.12 better) with exercise compared to controls. The minimally clinical important difference (MCID) is estimated to be 11 points. We are uncertain regarding the effect of exercise on functional mobility at discharge from the hospital compared to controls (8 studies, 2369 participants; very low-certainty evidence). Three studies used the Short Physical Performance Battery (SPPB) (scale: 0 to 12, higher scores representing better function) to measure functional mobility. Mean scores at discharge in the control groups ranged from 3.7 to 4.9 points on the SPPB, and the estimated effect of the exercise interventions was 0.78 points better (0.02 worse to 1.57 better). A change of 1 point on the SPPB represents an MCID. We are uncertain regarding the effect of exercise on the incidence of delirium during hospitalisation compared to controls (7 trials, 2088 participants; very low-certainty evidence). The incidence of delirium during hospitalisation was 88/1091 (81 per 1000) in the control group compared with 70/997 (73 per 1000; range 47 to 114) in the exercise group (RR 0.90, 95% CI 0.58 to 1.41). Exercise interventions may result in a small clinically unimportant improvement in QoL at discharge from the hospital compared to controls (4 studies, 875 participants; low-certainty evidence). Mean QoL on the EuroQol 5 Dimensions (EQ-5D) visual analogue scale (VAS) (scale: 0 to 100, higher scores representing better QoL) ranged between 48.9 and 64.7 in the control group at discharge from the hospital, and QoL was 6.04 points better (0.9 better to 11.18 better) with exercise. A change of 10 points on the EQ-5D VAS represents an MCID. No studies measured participant global assessment of success. Exercise interventions did not affect the risk of falls during hospitalisation (moderate-certainty evidence). The incidence of falls was 31/899 (34 per 1000) in the control group compared with 31/888 (34 per 1000; range 20 to 57) in the exercise group (RR 0.99, 95% CI 0.59 to 1.65). We are uncertain regarding the effect of exercise on the incidence of medical deterioration during hospitalisation (very low-certainty evidence). The incidence of medical deterioration in the control group was 101/1417 (71 per 1000) compared with 96/1313 (73 per 1000; range 44 to 120) in the exercise group (RR 1.02, 95% CI 0.62 to 1.68). Subgroup analyses by different intervention categories and by the use of a sham intervention were not meaningfully different from the main analyses. AUTHORS’ CONCLUSIONS: Exercise may make little difference to independence in activities of daily living or QoL, but probably does not result in more falls in older medical inpatients. We are uncertain about the effect of exercise on functional mobility, incidence of delirium and medical deterioration. Certainty of evidence was limited by risk of bias and inconsistency. Future primary research on the effect of exercise on acute hospitalisation could focus on more consistent and uniform reporting of participant’s characteristics including their baseline level of functional ability, as well as exercise dose, intensity and adherence that may provide an insight into the reasons for the observed inconsistencies in findings.
- PMID
- Keywords
Aged
Aged, 80 and over
Female
Humans
Male
Activities of Daily Living
*Delirium/epidemiology
Exercise
*Quality of Life
- Page(s)
- Volume
- Issue
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| Incidence of Postoperative Delirium Is Similar with Regional and General Anesthesia | Rosenberg, K. | Am J Nurs | 2022 |
Aged |
| Delirium and Delirium Severity Predict the Trajectory of the Hierarchical Assessment of Balance and Mobility in Hospitalized Older People: Findings From the DECIDE Study | Richardson, S. Murray, J. Davis, D. Stephan, B. C. M. Robinson, L. Brayne, C. Barnes, L. Parker, S. Sayer, A. A. Dodds, R. M. Allan, L. | J Gerontol A Biol Sci Med Sci | 2022 |
Aged |
| Anesthetic Practice Trends and Perceptions Toward Postoperative Delirium: A Mixed-Methods Analysis | Ragheb, J. Norcott, A. E. Iskander, M. Brooks, J. McKinney, A. Mentz, G. Vlisides, P. E | Anesth Analg | 2022 | |
| Preoperative Vitamin D Deficiency Is Associated With Postoperative Delirium in Critically Ill Patients | Qiu, Y. Sessler, D. I. Chen, L. Halvorson, S. Cohen, B. Bravo, M. Ince, I. Maheshwari, K. Kurz, A. | J Intensive Care Med | 2022 |
Adult |
| Physicians' beliefs and attitudes toward hypoactive delirium in the last days of life | Oya, K. Morita, T. Tagami, K. Matsuda, Y. Naito, A. S. Kashiwagi, H. Otani, H. | J Pain Symptom Manage | 2022 |
antipsychotic |
| Evidence-Based Guideline on Management of Postoperative Delirium in Older People for Low Resource Setting: Systematic Review Article | Mossie, A. Regasa, T. Neme, D. Awoke, Z. Zemedkun, A. Hailu, S. | Int J Gen Med | 2022 |
delirium prevention |
| Delirium diagnosis without a gold standard: Evaluating diagnostic accuracy of combined delirium assessment tools | Moss, S. J. Hee Lee, C. Doig, C. J. Whalen-Browne, L. Stelfox, H. T. Fiest, K. M. | PLoS One | 2022 |
Adult |
| Steroid dosing and delirium after lung transplant surgery | Mody, G. N. Choi, B. Townsend, K. Kerwin, C. Larios, D. Boukedes, S. Coppolino, A. Singh, S. Jin, G. Wolfe, D. Mallidi, H. Goldberg, H. | Gen Hosp Psychiatry | 2022 |
*Delirium/etiology |
| A systematic review of strategies for preventing delirium in patients undergoing vascular surgery | Meulenbroek, A. L. van Mil, S. R. Faes, M. C. Mattace-Raso, F. U. S. Fourneau, I. van der Laan, L. | Ann Vasc Surg | 2022 |
Aneurysm of the abdominal aorta |
| The impact of perioperative stroke and delirium on outcomes after surgical aortic valve replacement | Messé, S. R. Overbey, J. R. Thourani, V. H. Moskowitz, A. J. Gelijns, A. C. Groh, M. A. Mack, M. J. Ailawadi, G. Furie, K. L. Southerland, A. M. James, M. L. Moy, C. S. Gupta, L. Voisine, P. Perrault, L. P. Bowdish, M. E. Gillinov, A. M. O'Gara, P. T. Ou | J Thorac Cardiovasc Surg | 2022 |
aortic valve |
| Tau as a serum biomarker of delirium after major cardiac surgery: a single centre case-control study | McKay, T. B. Qu, J. Liang, F. Mueller, A. Wiener-Kronish, J. Xie, Z. Akeju, O. | Br J Anaesth | 2022 |
Alzheimer’s disease |
| Insulinoma: an uncommon cause of delirium | McComb, K. Roulston, G. Armstrong, L. | Age Ageing | 2022 |
Aged |
| The Twilight Zone: Oxybutynin Overuse Exacerbating Delirium | Marthi, S. Pomerantz, M. A. Mernan, A. J. Berlow, Y. A. | J Geriatr Psychiatry Neurol | 2022 |
anticholinergic medications |
| Corrigendum: Risk Factors for Delirium Are Different in the Very Old: A Comparative One-Year Prospective Cohort Study of 5,831 Patients | Marquetand, J. Bode, L. Fuchs, S. Hildenbrand, F. Ernst, J. von Känel, R. Boettger, S. | Front Psychiatry | 2022 |
comparison |
| The development of the MENTOR_D nursing intervention: Supporting family involvement in delirium management | Mailhot, T. Cossette, S. Lavoie, P. Maheu-Cadotte, M. A. Fontaine, G. Bourbonnais, A. Côté, J. | Int J Older People Nurs | 2022 |
delirium |
| Factors Associated With Severity of Delirium Complicating COVID-19 in Intensive Care Units | Madonna, D. Enrico, P. Ciappolino, V. Boscutti, A. Colombo, E. Turtulici, N. Cantù, F. Cereda, G. Delvecchio, G. De Falco, S. Chierichetti, M. Savioli, M. Grasselli, G. Brambilla, P. | Front Neurol | 2022 |
Ards |
| An open-label clinical trial of oral transmucosal haloperidol and oral transmucosal olanzapine in the treatment of terminal delirium at home | Lyu, X. J. Kan, A. D. Chong, P. H. Lin, K. Koh, Y. H. Yeo, Z. Z. | Trials | 2022 |
*Antipsychotic Agents/adverse effects |
| Family-centred care interventions to reduce the delirium prevalence in critically ill patients: A systematic review and meta-analysis | Lin, L. Peng, Y. Zhang, H. Huang, X. Chen, L. Lin, Y. | Nurs Open | 2022 |
delirium |
| White-Cell Derived Inflammatory Biomarkers in Prediction of Postoperative Delirium in Elderly Patients Undergoing Surgery for Lower Limb Fracture Under Non-General Anaesthesia | Li, X. Wang, G. He, Y. Wang, Z. Zhang, M. | Clin Interv Aging | 2022 |
Aged |
| Comparative salary-related costs of a brief app-directed delirium identification protocol by hospitalists, nurses, and nursing assistants | Leslie, D. L. Fick, D. M. Moore, A. Inouye, S. K. Jung, Y. Ngo, L. H. Boltz, M. Husser, E. Shrestha, P. Boustani, M. Marcantonio, E. R. | J Am Geriatr Soc | 2022 |
cost-analysis |
| Investigation and treatment of asymptomatic bacteriuria in older patients with delirium: a cross-sectional survey of Canadian physicians | Laguë, A. Boucher, V. Joo, P. Yadav, K. Morasse, C. Émond, M. | Cjem | 2022 |
Aged |
| APOE e4 Genotypes Increase Risk of Delirium During COVID-19-Related Hospitalizations: Evidence From a Large UK Cohort | Kuo, C. L. Pilling, L. C. Atkins, J. L. Fortinsky, R. H. Kuchel, G. A. Melzer, D. | J Gerontol A Biol Sci Med Sci | 2022 |
Alleles |
| Nurses' Knowledge about Delirium in the Group of Intensive Care Units Patients | Krupa, S. Friganović, A. Oomen, B. Benko, S. Mędrzycka-Dąbrowska, W. | Int J Environ Res Public Health | 2022 |
Clinical Competence |
| Early Ambulation to Prevent Delirium After Long-Time Head and Neck Cancer Surgery | Kim, J. H. Lee, Y. S. Kim, Y. H. Cho, K. J. Jung, Y. H. Choi, S. H. Nam, S. Y. Kim, S. Y. | Front Surg | 2022 |
ambulation |
| The effect of regional nerve block on perioperative delirium in hip fracture surgery for the elderly: A systematic review and meta-analysis of randomized controlled trials | Kim, C. H. Yang, J. Y. Min, C. H. Shon, H. C. Kim, J. W. Lim, E. J. | Orthop Traumatol Surg Res | 2022 |
Aged |
| Role of multicomponent non-pharmacological nursing interventions on delirium prevention: A randomized controlled study | Kasapoğlu, E. S. Enç, N. | Geriatr Nurs | 2022 |
Critical Illness |
| Early Intervention of Perioperative Delirium in Older Patients (>60 years) with Hip Fracture: A Randomized Controlled Study | Jing, G. W. Xie, Q. Tong, J. Liu, L. Z. Jiang, X. Si, L. | Orthop Surg | 2022 |
Delirium |
| Functional Outcome in Patients with Chronic Subdural Hematoma: Postoperative Delirium and Operative Procedure | Ishida, T. Inoue, T. Inoue, T. Saito, A. Suzuki, S. Uenohara, H. Tominaga, T. | Neurol Med Chir (Tokyo) | 2022 |
*Delirium/etiology |
| Delirium in geriatric patients | Iglseder, B. Frühwald, T. Jagsch, C. | Wien Med Wochenschr | 2022 |
Aged |
| Recognizing Intensive Care Unit Delirium: Are Critical Care Nurses Ready? | Ho, M. H. Chang, H. R. Liu, M. F. Chen, K. H. Shen Hsiao, S. T. Traynor, V. | J Nurs Res | 2022 | |
| Effect of an evidence-based poster on the knowledge of delirium and its prevention in student nurses: A quasi-experimental study | Glass, G. F. Tan, H. Chan, E. Y. | Contemp Nurse | 2022 |
Aged |
| Lack of Association Between Perioperative Medication and Postoperative Delirium in Hip Fracture Patients in an Orthogeriatric Care Pathway | Genet, B. Lamy, T. Cohen-Bittan, J. Glasman, P. Verny, M. Riou, B. Boddaert, J. Zerah, L. | J Am Med Dir Assoc | 2022 |
Aged |
| Dexmedetomidine after Cardiac Surgery for Prevention of Delirium (EXACTUM) trial protocol: a multicentre randomised, double-blind, placebo-controlled trial | Gargadennec, T. Oilleau, J. F. Rozec, B. Nesseler, N. Lasocki, S. Futier, E. Amour, J. Durand, M. Bougle, A. Kerforne, T. Consigny, M. Eddi, D. Huet, O. | BMJ Open | 2022 |
Aged |
| Validation of E-PRE-DELIRIC in cardiac surgical ICU delirium: A retrospective cohort study | Gao, W. Zhang, Y. Jin, J. | Nurs Crit Care | 2022 |
Adult |
| Association Between Sedative Medication Administration and Delirium Development in a Medical Intensive Care Unit | Franz, N. D. Alaniz, C. Miller, J. T. Farina, N. | J Pharm Pract | 2022 |
benzodiazepine |
| Nurse-Driven Assessment, Prevention, and Management of Delirium on an Acute Inpatient Neurology Unit | Francisco, M. A. Gesell, T. Meletis, S. Bohr, N. L. Gleason, L. J. | J Nurs Care Qual | 2022 | |
| Delirium the next frontier | Fong, T. G. Inouye, S. K. | J Gerontol A Biol Sci Med Sci | 2022 |
*Delirium/diagnosis/etiology |
| Presurgical Thalamus Volume in Postoperative Delirium: A Longitudinal Observational Cohort Study in Older Patients | Fislage, M. Feinkohl, I. Pischon, T. Spies, C. D. Borchers, F. Winterer, G. Zacharias, N. | Anesth Analg | 2022 | |
| The association between preoperative Mini-Cog© score and postoperative delirium (POD): a retrospective cohort study | Fiamanya, S. Ma, S. Yates, D. R. A. | Perioper Med (Lond) | 2022 |
Cognitive impairment |
| Delirium severity in critical patients with COVID-19 from an Infectious Disease Intensive Care Unit | Dias, R. Caldas, J. P. Silva-Pinto, A. Costa, A. Sarmento, A. Santos, L. | Int J Infect Dis | 2022 |
*COVID-19/complications |
| Health-Related Quality of Life Following Delirium in the PICU | Dervan, L. A. Killien, E. Y. Smith, M. B. Watson, R. S. | Pediatr Crit Care Med | 2022 |
Aftercare |
| Cuartas, C. F. Davis, M. | Valproic Acid in the Management of Delirium | Am J Hosp Palliat Care | 2022 |
Adult |
| Assessing the Accuracy of International Classification of Diseases (ICD) Coding for Delirium | Chuen, V. L. Chan, A. C. H. Ma, J. Alibhai, S. M. H. Chau, V. | J Appl Gerontol | 2022 |
*Delirium/diagnosis |
| Evaluation of the Impact of Prior-to-Admission Sleep Aid Prescribing Practices on Sleep and Delirium in the Intensive Care Unit | Chudow, M. Paradiso, V. Silva, N. Collette, J. | Ann Pharmacother | 2022 |
Adult |
| Chou, S. T. Pogach, M. Rock, L. K. | Less pharmacotherapy is more in delirium | Intensive Care Med | 2022 | |
| A randomized trial: bispectral-guided anesthesia decreases incidence of delayed neurocognitive recovery and postoperative neurocognitive disorder but not postoperative delirium | Chen, X. Li, L. Yang, L. Li, A. Wu, M. Yu, D. | Am J Transl Res | 2022 |
BIS monitoring |
| Comparative effectiveness of non-pharmacological interventions for preventing delirium in critically ill adults: A systematic review and network meta-analysis | Chen, T. J. Traynor, V. Wang, A. Y. Shih, C. Y. Tu, M. C. Chuang, C. H. Chiu, H. Y. Chang, H. R. | Int J Nurs Stud | 2022 |
Delirium |
| Influence of Renin-Angiotensin System Inhibitors on Postoperative Delirium in Patients With Pulmonary Arterial Hypertension: A Secondary Analysis of a Retrospective Cohort Study | Chen, G. Zhou, S. Deng, F. | Front Psychiatry | 2022 |
ACEIs |
| Delirium in COVID‑19 pneumonia: looking inside the geriatric unit-reply | Callea, A. Conti, G. Caporotundo, S. Della Marca, G. Rollo, E. | Intern Emerg Med | 2022 | |
| Postoperative delirium in the elderly: time to focus on pre- and postoperative management | Bruder, N. | Minerva Anestesiol | 2022 |
Aged |
| Improving ABCDEF Bundle Compliance and Clinical Outcomes in the ICU: Randomized Control Trial to Assess the Impact of Performance Measurement, Feedback, and Data Literacy Training | Brown, J. C. Querubin, J. A. Ding, L. Mack, W. J. Chen-Chan, K. Perez, F. Barr, J. Peden, C. J. Cobb, J. P. | Crit Care Explor | 2022 |
ABCDEF bundle compliance |
| Impact of Cerebral Embolic Protection Devices on the Incidence and Outcomes of Delirium After Transcatheter Aortic Valve Implantation | Bansal, A. Kumar, A. Reed, G. W. Puri, R. Krishnaswamy, A. Linke, A. Yun, J. Kapadia, S. R. | Am J Cardiol | 2022 | |
| Postoperative delirium in older patients after undergoing pelvic organ prolapse surgery | Ackenbom, M. F. Zyczynski, H. M. Butters, M. A. Lopa, S. Orris, S. R. Davis, E. M. | nt Urogynecol J | 2022 |
Cognitive impairment |
| Use of naldemedine is associated with reduced incidence of hyperactive delirium in cancer patients with opioid-induced constipation: a nationwide retrospective cohort study in Japan | Abe, H. Sumitani, M. Matsui, H. Inoue, R. Fushimi, K. Uchida, K. Yasunaga, H. | Pharmacotherapy | 2022 |
delirium |
| Effect of light therapy on delirium in older patients with Alzheimer's disease-related dementia | Zou, C. Mei, X. Li, X. Hu, J. Xu, T. Zheng, C. | J Psychiatr Res | 2022 |
Alzheimer’s disease |
| Association of antipsychotic dose with survival of advanced cancer patients with delirium | Yokomichi, N. Maeda, I. Morita, T. Yoshiuchi, K. Ogawa, A. Hisanaga, T. Sakashita, A. Nakahara, R. Kaneishi, K. Iwase, S. | Ann Palliat Med | 2022 |
Advanced cancer |
| Systematic review and meta-analysis on the incidence of delirium in intensive care unit inpatients after cognitive exercise intervention | Xu, C. Chen, Z. Zhang, L. Guo, H. | Ann Palliat Med | 2022 |
Cognition |
| Electroencephalography in delirium assessment: a scoping review | Wiegand, T. L. T. Rémi, J. Dimitriadis, K. | BMC Neurol | 2022 |
*Delirium/diagnosis/etiology |
| Prophylactic melatonin for delirium in intensive care (Pro-MEDIC): a randomized controlled trial | Wibrow, B. Martinez, F. E. Myers, E. Chapman, A. Litton, E. Ho, K. M. Regli, A. Hawkins, D. Ford, A. van Haren, F. M. P. Wyer, S. McCaffrey, J. Rashid, A. Kelty, E. Murray, K. Anstey, M. | Intensive Care Med | 2022 |
Australia |
| Effect of Electroencephalography Spectral Edge Frequency (SEF) and Patient State Index (PSI)-Guided Propofol-Remifentanil Anesthesia on Delirium After Laparoscopic Surgery: The eMODIPOD Randomized Controlled Trial | Wang, E. Wang, L. Ye, C. Luo, N. Zhang, Y. Zhong, Y. Zhu, M. Zou, Y. Li, Q. Li, L. Song, Z. Luo, H. Dai, F. Liu, H. Gelb, A. W. Guo, Q. Meng, L. | J Neurosurg Anesthesiol | 2022 |
*Anesthesia/adverse effects |
| Hospitalisation costs and Health Related Quality of Life in delirious patients; a scoping review | van Lieshout, C. Schuit, E. Hermes, C. Kerrigan, M. Frederix, G. W. J. | Z Evid Fortbild Qual Gesundhwes | 2022 |
Cost Analysis |
| Rapid cognitive assessment tools for screening of mild cognitive impairment in the preoperative setting: A systematic review and meta-analysis | Tran, J. Nimojan, T. Saripella, A. Tang-Wai, D. F. Butris, N. Kapoor, P. Berezin, L. Englesakis, M. Chung, F. | J Clin Anesth | 2022 |
Cognition |
| Physostigmine for Facilitation of Care in Clozapine-Associated Anticholinergic Delirium | Spring, J. D. Goldstein, B. N. Buster, M. Mahmoud, A. A. Hamm, B. | J Clin Psychopharmacol | 2022 | |
| Relationship between no-visitation policy and the development of delirium in patients admitted to the intensive care unit | Shinohara, F. Unoki, T. Horikawa, M. | PLoS One | 2022 |
Apache |
| USING A REAL-TIME ABCDEF COMPLIANCE TOOL TO UNDERSTAND THE ROLE OF BUNDLE ELEMENTS IN MORTALITY AND DELIRIUM | Shampo, J. C. Wenszell, K. Luo-Owen, X. Mukherjee, N. Cochran-Yu, M. Swentek, L. Burruss, S. K. Markovich, S. Turay, D. Dorotta, I. R. Mukherjee, K. | J Trauma Acute Care Surg | 2022 | |
| Post-discharge Mortality in Patients With Delirium and Dementia: A 3-Year Follow Up Study | Schnorr, T. Fleiner, T. Schroeder, H. Reupke, I. Woringen, F. Trumpf, R. Schroeder, S. Zijlstra, W. Haussermann, P. | Front Psychiatry | 2022 |
aftercare |
| Effects of Physical Exercise on the Incidence of Delirium and Cognitive Function in Acutely Hospitalized Older Adults: A Systematic Review with Meta-Analysis | Sáez de Asteasu, M. L. Cuevas-Lara, C. García-Hermoso, A. Ramírez-Vélez, R. Martínez-Velilla, N. Zambom-Ferraresi, F. Cadore, E. L. Izquierdo, M. | J Alzheimers Dis | 2022 |
Physical exercise |
| Associations Between Stroke Localization and Delirium: A Systematic Review and Meta-Analysis | Rhee, J. Y. Colman, M. A. Mendu, M. Shah, S. J. Fox, M. D. Rost, N. S. Kimchi, E. Y. | J Stroke Cerebrovasc Dis | 2022 |
*Delirium/epidemiology |
| The family in preventing delirium in the intensive care unit: Scoping review | Pabón-Martínez, B. A. Rodríguez-Pulido, L. I. Henao-Castaño, A. M. | Enferm Intensiva (Engl Ed) | 2022 |
Adult |
| The effect of delirium preventive measures on the occurrence of postoperative cognitive dysfunction in older adults undergoing cardiovascular surgery. The DelPOCD randomised controlled trial | Olotu, C. Ascone, L. Wiede, J. Manthey, J. Kuehn, S. Scherwath, A. Kiefmann, R. | J Clin Anesth | 2022 |
Aged |
| Pharmacotherapy for elderly patients with delirium in a general ward setting: A retrospective study | Ohsako, N. Hashimoto, T. Shiko, Y. Kawasaki, Y. Nakagawa, M. Okuma, T. Kurata, T. Suzuki, H. Ishige, M. Kikuchi, S. | Asian J Psychiatr | 2022 |
Aged |
| Regional cerebral hypometabolism on 18F-FDG PET/CT scan in delirium is independent of acute illness and dementia | Nitchingham, A. Pereira, J. V. Wegner, E. A. Oxenham, V. Close, J. Caplan, G. A. | Alzheimers Dement | 2022 |
18F-fluorodeoxyglucose positron emission tomography |
| Delirium screening with 4AT in patients aged 65 years and older admitted to the Emergency Department with suspected sepsis: a prospective cohort study | Myrstad, M. Kuwelker, K. Haakonsen, S. Valebjørg, T. Langeland, N. Kittang, B. R. Hagberg, G. Neerland, B. E. Bakken, M. S. | Eur Geriatr Med | 2022 |
Aged |
| The DEMS-DOSS study: validating a delirium monitoring tool in hospitalised older adults | Montgomery, A. Todd, J. A. Jones, C. Koroitamana, J. Grealish, L. Wand, A. Billett, S. Teodorczuk, A. | Age Ageing | 2022 |
Aged |
| Effectiveness of Interprofessional Consultation-Based Interventions for Delirium: A Scoping Review | Monaghan, C. Martin, G. Kerr, J. Peters, M. L. Versloot, J. | J Appl Gerontol | 2022 |
Accidental Falls/prevention & control |
| PRe-Operative Prediction of postoperative DElirium by appropriate SCreening (PROPDESC) development and validation of a pragmatic POD risk screening score based on routine preoperative data | Menzenbach, J. Kirfel, A. Guttenthaler, V. Feggeler, J. Hilbert, T. Ricchiuto, A. Staerk, C. Mayr, A. Coburn, M. Wittmann, M. | J Clin Anesth | 2022 |
*Delirium/diagnosis/epidemiology/etiology |
| Behavioral Variant Frontotemporal Dementia and Social and Criminal Transgressions | Mendez, M. F. | J Neuropsychiatry Clin Neurosci | 2022 |
Cognition |
| Effects of Abdominal Wall Blocks on Postoperative Delirium in Elderly Patients Undergoing Laparoscopic Surgery: A Randomized Controlled Study | Liu, T. Tuo, J. Wei, Q. Sun, X. Zhao, H. Zhao, X. Qu, M. | Med Sci Monit | 2022 |
Aged |
| Preoperative Status of Gut Microbiota Predicts Postoperative Delirium in Patients With Gastric Cancer | Liu, H. Cheng, G. Xu, Y. L. Fang, Q. Ye, L. Wang, C. H. Liu, X. S. | Front Psychiatry | 2022 |
Shigella |
| Nurses' experiences in the management of delirium among older persons in acute care ward settings: A qualitative systematic review and meta-aggregation | Lim, X. M. Lim, Z. H. T. Ignacio, J. | Int J Nurs Stud | 2022 |
Aged |
| Predicting hospital mortality and length of stay: A prospective cohort study comparing the Intensive Care Delirium Screening Checklist versus Confusion Assessment Method for the Intensive Care Unit | Li, H. C. Chen, C. C. Yeh, T. Y. Liao, S. C. Hsu, A. S. Wei, Y. C. Shun, S. C. Ku, S. C. Inouye, S. K. | Aust Crit Care | 2022 |
CAM-ICU (Confusion Assessment Method for Intensive Care Unit) |
| Can we improve delirium prevention and treatment in the emergency department? A systematic review | Lee, S. Chen, H. Hibino, S. Miller, D. Healy, H. Lee, J. S. Arendts, G. Han, J. H. Kennedy, M. Carpenter, C. R. | J Am Geriatr Soc | 2022 |
delirium |
| Prevalence, management and outcomes of unrecognized delirium in a National Sample of 1,493 older emergency department patients: how many were sent home and what happened to them? | Lee, J. S. Tong, T. Chignell, M. Tierney, M. C. Goldstein, J. Eagles, D. Perry, J. J. McRae, A. Lang, E. Hefferon, D. Rose, L. Kiss, A. Borgundvaag, B. McLeod, S. Melady, D. Boucher, V. Sirois, M. J. Émond, M. | Age Aging | 2022 |
*Aftercare |
| COVID-19 severity and age increase the odds of delirium in hospitalized adults with confirmed SARS-CoV-2 infection: a cohort study | LaHue, S. C. Escueta, D. P. Guterman, E. L. Patel, K. Harrison, K. L. Boscardin, W. J. Douglas, V. C. Newman, J. C. | BMC Psychiatry | 2022 |
Adult |
| Outcomes in heart failure patients discharged to skilled nursing facilities with delirium | Lafo, J. Singh, M. Jiang, L. Correia, S. Madrigal, C. Clements, R. Wu, W. C. Erqou, S. Rudolph, J. L. | ESC Heart Fail | 2022 |
Delirium |
| Distribution of delirium motor subtypes in the intensive care unit: a systematic scoping review | la Cour, K. N. Andersen-Ranberg, N. C. Weihe, S. Poulsen, L. M. Mortensen, C. B. Kjer, C. K. W. Collet, M. O. Estrup, S. Mathiesen, O. | Crit Care | 2022 |
Aged |
| Factors associated with post-operative delirium in hip fracture patients: what should we care | Kong, D. Luo, W. Zhu, Z. Sun, S. Zhu, J. | Eur J Med Res | 2022 |
Aged |
| Factors Associated With Postoperative Delirium in Patients Undergoing Complex Head and Neck Flap Surgery | Kolk, A. Schwarzer, C. Wolff, K. D. Grill, F. Weingart, J. | J Oral Maxillofac Surg | 2022 |
Adolescent |
| Increased postoperative myeloperoxidase concentration associated with low baseline antioxidant capacity as the risk factor of delirium after cardiac surgery | Kaźmierski, J. Miler, P. Pawlak, A. Jerczyńska, H. Nowakowska, K. Walkiewicz, G. Woźniak, K. Krejca, M. Wilczyński, M. | Ann Med | 2022 |
Antioxidants |
| Could neutrophil-to-lymphocyte ratio predict mortality in community-dwelling older people with delirium superimposed on dementia? | Katipoglu, B. Naharci, M. I. | Aging Clin Exp Res | 2022 |
Delirium |
| The efficacy and safety of nurse-initiated sedation management in an intensive care unit: A two-phase prospective study in Japan | Kanda, N. Nakano, H. Naraba, H. Kawasaki, A. Ohno, N. Yoshikawa, Y. Sakuramoto, H. Takahashi, Y. Sonoo, T. Hashimoto, H. Nakamura, K. | Jpn J Nurs Sci | 2022 |
Richmond Agitation-Sedation Scale |
| Albumin/fibrinogen ratio, an independent risk factor for postoperative delirium after total joint arthroplasty | Jiang, L. Lei, G. | Geriatr Gerontol Int | 2022 |
albumin/fibrinogen ratio |
| Association of preoperative vitamin D deficiency with the risk of postoperative delirium and cognitive dysfunction: A meta-analysis | Hung, K. C. Wang, L. K. Lin, Y. T. Yu, C. H. Chang, C. Y. Sun, C. K. Chen, J. Y. | J Clin Anesth | 2022 |
Postoperative cognitive dysfunction |
| Sailing in a sea of perplexity: Family caregivers' experience of patients with delirium | Huang, L. J. Tsai, H. H. Wang, Y. W. Chou, C. L. | Nurs Crit Care | 2022 |
*Caregivers |
| Association Between Hypernatremia and Delirium After Cardiac Surgery: A Nested Case-Control Study | Hong, L. Shen, X. Shi, Q. Song, X. Chen, L. Chen, W. Chen, S. Xue, Y. Zhang, C. Zhou, J. | Front Cardiovasc Med | 2022 |
cardiac surgery |
| Harmonization of Four Delirium Instruments: Creating Crosswalks and the Delirium Item-Bank (DEL-IB) | Helfand, B. K. I. Detroyer, E. Milisen, K. Adamis, D. Metzger, E. D. Boudreaux, E. D. Inouye, S. K. Jones, R. N. | Am J Geriatr Psychiatry | 2022 |
Aged |
| Does delirium prevention reduce risk of in-patient falls among older adults? A systematic review and trial sequential meta-analysis | He, S. Rolls, K. Stott, K. Shekhar, R. Vueti, V. Flowers, K. Moseley, M. Shepherd, B. Mayahi-Neysi, M. Chasle, B. Warner, B. Ni Chroinin, D. Frost, S. A. | Australas J Ageing | 2022 |
accidental falls |
| Detection of delirium by family members in the intensive care unit: Translation, Cross-Cultural adaptation and validation of the Family Confusion Assessment Method for the German-Speaking area | Greindl, S. Weiss, B. Magnolini, R. Lingg, C. Mayer, H. Schaller, S. J. | J Adv Nurs | 2022 |
Family Confusion Assessment Method |
| Patient-related risk factors for in-hospital functional decline in older adults: A systematic review and meta-analysis | Geyskens, L. Jeuris, A. Deschodt, M. Van Grootven, B. Gielen, E. Flamaing, J. | Age Ageing | 2022 |
*Activities of Daily Living |
| Screening for delirium and dementia in older hospitalised adults in Zambia | George, G. Fricker, M. Todd, O. Makowa, D. Tembo, C. Dotchin, C. Gray, W. K. Walker, R. W. Mbwele, B. Paddick, S. M. | J Neurol Sci | 2022 |
Delirium |