Delirium Bibliography

Delirium Bibliography books graphicWhat is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!

How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.

Reference Information

Title
S100β as a potential biomarker of incident delirium: a systematic review and meta-analysis
Authors
Zhang, X. Lyu, Y. Wang, D.
Year
2020
Journal
Minerva Anestesiol
Abstract

INTRODUCTION: Delirium is an acute and fluctuating change in cognition, attention and consciousness, defined as an acute neuropsychiatric syndrome, but mechanism is extremely complex and still not well understood. Recently, the S100 calcium-binding protein B protein (S100β) has received attention in the biomarker research area of delirium. This meta-analysis was designed to investigate the relationship between S100β levels and delirium. EVIDENCE ACQUISITION: We conducted a systematic literature search of MEDLINE (via PubMed search engine), Ovid, EMBASE, and Cochrane Library electronic databases for case-control studies measuring S100β levels from delirium and no delirium controls. Extracted data were analyzed with STATA. The standardized mean difference (SMD) and the 95% confidence interval (95%CI) were calculated using a random effect model. EVIDENCE SYNTHESIS: We identified ten eligible studies including 1739 patients. The pooled SMD showed significant difference in S100β between delirium patients and control (SMD: 0.88; 95%CI: 0.31 to 1.46), but there was high heterogeneity (I2: 95.9%; p=0.000). Further subgroup analysis showed significant differences in Cerebrospinal Fluid (CSF) S100β (SMD: 0.87; 95%CI: 0.20 to 1.53) and low heterogeneity (I259.8%; p=0.115). CONCLUSIONS: This meta-analysis provides evidence that serum S100β seems to be of limited value as a biomarker of delirium, but CSF S100β elevation as a biomarker of delirium, may be more meaningful.

PMID

32449338

Keywords
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Total Records Found: 6300, showing 100 per page
TitleAuthorsJournalYearKeywords
Prophylactic use of ramelteon for delirium in hospitalized patients: A systematic review and meta-analyses Dang, V. Mansukhani, M. P. Wang, Z. Vesely, E. K. Kolla, B. P. J Acad Consult Liaison Psychiatry 2022

Delirium
prevention
ramelteon

Longest and largest cohort study of delirium to date reinforces association while causation remains elusive Cunningham, E. J Neurol Neurosurg Psychiatry 2022

Cognition
Dementia

Documentation and Diagnosis of Delirium in Parkinson's Disease Cullinan, R. J. Richardson, S. J. Yarnall, A. J. Burn, D. J. Allan, L. M. Lawson, R. A. Acta Psychiatr Scand 2022

Confusion
Delirium
Diagnosis
Parkinson Disease

Avoiding pitfalls in the treatment of delirium Chuang, Y. C. Lin, C. Y. Wang, J. K. Aust N Z J Psychiatry 2022

*Delirium/drug therapy
Humans

Less pharmacotherapy is more in delirium Chou, S. T. Pogach, M. Rock, L. K. Intensive Care Med 2022

*Antipsychotic Agents/therapeutic use
*Delirium/drug therapy
Humans

Accuracies of Training Labels and Machine Learning Models: Experiments on Delirium and Simulated Data Cheng, Y. Shao, Y. Rudolph, J. Weir, C. R. Sahlmann, B. Zeng-Treitler, Q. Stud Health Technol Inform 2022

*Delirium
Humans
*Machine Learning
Support Vector Machine
delirium
weak supervised learning

E4BP4 Coordinates Circadian Control of Cognition in Delirium Chen, M. Zhang, L. Shao, M. Du, J. Xiao, Y. Zhang, F. Zhang, T. Li, Y. Zhou, Q. Liu, K. Wang, Z. Wu, B. Adv Sci (Weinh) 2022

E4bp4
Erk1/2
circadian rhythm
delirium
microglia

Association Between Anesthetics and Postoperative Delirium in Elderly Patients Undergoing Spine Surgery: Propofol Versus Sevoflurane Chang, J. E. Min, S. W. Kim, H. Won, D. Lee, J. M. Kim, T. K. Kim, C. Hwang, J. Y. Global Spine J 2022

anesthesia
delirium
elderly
propofol
sevoflurane

Validation of a delirium predictive model in patients admitted to surgical intensive care units: a multicentre prospective observational cohort study Chaiwat, O. Chittawatanarat, K. Mueankwan, S. Morakul, S. Dilokpattanamongkol, P. Thanakiattiwibun, C. Siriussawakul, A. BMJ Open 2022

Adult
Aged
Aged, 80 and over
Critical Care
Critical Illness
*Delirium/diagnosis/epidemiology/etiology
Humans
*Intensive Care Units
Middle Aged
Prospective Studies
adult intensive & critical care
delirium & cognitive disorders
intensive & critical care

Lidocaine Infusion for the Management of Postoperative Pain and Delirium (LIMPP): protocol for a randomised control trial Buren, M. A. Theologis, A. Zuraek, A. Behrends, M. Clark, A. J. Leung, J. M. BMJ Open 2022

Aged
Analgesics, Opioid/adverse effects
*Delirium/drug therapy/etiology/prevention & control
Double-Blind Method
Humans
*Lidocaine/therapeutic use
Pain, Postoperative/complications/drug therapy/prevention & control
Randomized Controlled Trials as Topic
Anaesthesia in orthopaedics
Geriatric medicine
Neurosurgery
Pain management
Spine

Factors influencing resilience to postoperative delirium in adults undergoing elective orthopaedic surgery Bowman, E. M. L. Cardwell, C. McAuley, D. F. McGuinness, B. Passmore, A. P. Beverland, D. Zetterberg, H. Schott, J. M. Cunningham, E. L. Br J Surg 2022
Delirium prediction in the ICU: designing a screening tool for preventive interventions Bhattacharyya, A. Sheikhalishahi, S. Torbic, H. Yeung, W. Wang, T. Birst, J. Duggal, A. Celi, L. A. Osmani, V. JAMIA Open 2022

artificial intelligence
clinical decision support
delirium
machine learning
nursing assessment
predictive modeling

Regional vs General Anesthesia and Incidence of Postoperative Delirium in Older Patients Undergoing Hip Fracture Surgery Zhu, Z. Cao, P. Lin, L. Jama 2022

Aged
*Anesthesia, Conduction/adverse effects
*Anesthesia, General/adverse effects
*Delirium/epidemiology/etiology
*Hip Fractures/epidemiology/surgery
Humans
Incidence
Postoperative Complications/epidemiology/etiology

Melatonin intervention to prevent delirium in hospitalized patients: A meta-analysis You, W. Fan, X. Y. Lei, C. Nie, C. C. Chen, Y. Wang, X. L. World J Clin Cases 2022

Delirium
Melatonin
Meta-analysis
Prevention
Randomized controlled trial

Preoperative Low Physical Activity is a Predictor of Postoperative Delirium in Patients with Gastrointestinal Cancer: A Retrospective Study Yanagisawa, T. Tatematsu, N. Horiuchi, M. Migitaka, S. Yasuda, S. Itatsu, K. Kubota, T. Sugiura, H. Asian Pac J Cancer Prev 2022

Activities of Daily Living
*Delirium/diagnosis/etiology
Exercise
*Gastrointestinal Neoplasms/complications/surgery
Humans
Retrospective Studies
Gastrointestinal cancer
physical activity
postoperative delirium

What is It Like to be Delirious? Wijdicks, E. F. M. Rabinstein, A. A. Neurocrit Care 2022

Definitions
Delirium
Encephalopathy
Hallucinations
Pathophysiology

Impact of Pain, Agitation, and Delirium Bundle on Delirium and Cognitive Function Wang, X. P. Lv, D. Chen, Y. F. Chen, N. Li, X. D. Xu, C. F. Li, Y. Tian, L. J Nurs Res 2022
Regional vs General Anesthesia and Incidence of Postoperative Delirium in Older Patients Undergoing Hip Fracture Surgery Uzoigwe, C. E. Campbell-Jones, F. Jama 2022

Aged
*Anesthesia, Conduction/adverse effects
*Anesthesia, General/adverse effects
*Delirium/epidemiology/etiology
*Hip Fractures/epidemiology/surgery
Humans
Incidence
Postoperative Complications/epidemiology/etiology

Improving delirium screening in older adults at the Royal United Hospital, Bath Trew, C. A. Cross, R. Howell, K. Dyer, C. Br J Hosp Med (Lond) 2022

Aged
*Delirium/diagnosis/prevention & control
Hospitalization
Hospitals, University
Humans
Inpatients
Mass Screening
Audit
Delirium
Quality improvement
Screening

Assessing prevalence and independent predictors of postoperative delirium in patients with head and neck cancer Tian, T. Xue, F. S. Shao, L. J. Z. Hu, B. Br J Oral Maxillofac Surg 2022

*Delirium/epidemiology/etiology
*Head and Neck Neoplasms/surgery
Humans
Postoperative Complications/epidemiology
Prevalence
Risk Factors
Head and neck cancer
Postoperative care
Postoperative delirium
Prediction
Risk factors

Delirium due to hip fracture is associated with activated immune-inflammatory pathways and a reduction in negative immunoregulatory mechanisms Thisayakorn, P. Thipakorn, Y. Tantavisut, S. Sirivichayakul, S. Maes, M. BMC Psychiatry 2022

Aged
Biomarkers
Cytokines
*Delirium/complications
*Hip Fractures/complications/surgery
Humans
Tumor Necrosis Factor-alpha
Delirium
Hip fracture
Inflammation
Neurocognition
Neuroimmune

Retrospective evaluation of a delirium order set utilizing nonpharmacologic and pharmacologic interventions for the treatment of delirium in medical intensive care unit patients Taylor, A. D. Chen, A. Reddy, A. J. Lewandowski, A. Torbic, H. Am J Health Syst Pharm 2022

Adolescent
Adult
*Antipsychotic Agents/therapeutic use
*Delirium/diagnosis/drug therapy
Humans
Intensive Care Units
Patient Discharge
Retrospective Studies
*antipsychotic
*central nervous system
*clinical pathway
*critical care
*delirium
*drug utilization

Prevention of dexmedetomidine on postoperative delirium and early postoperative cognitive dysfunction in elderly patients undergoing hepatic lobectomy Tang, Y. Wang, Y. Kong, G. Zhao, Y. Wei, L. Liu, J. Zhong Nan Da Xue Xue Bao Yi Xue Ban 2022

Aged
Aged, 80 and over
Bradycardia
*Cognitive Dysfunction/etiology/prevention & control
*Delirium/drug therapy/epidemiology/prevention & control
*Dexmedetomidine/therapeutic use
Humans
*Hypotension/complications/drug therapy
Interleukin-10
Middle Aged
*Postoperative Cognitive Complications/prevention & control
Postoperative Complications/epidemiology
Prospective Studies
Tumor Necrosis Factor-alpha
dexmedetomidine
elderly patients
hepatic lobectomy
postoperative cognitive dysfunction
postoperative delirium

Prevalence, clinical features, and risk factors of delusions in patients with delirium Tachibana, M. Inada, T. Ichida, M. Ozaki, N. Int J Geriatr Psychiatry 2022
Effect of sedative premedication with oral midazolam on postanesthesia care unit delirium in older adults: a secondary analysis following an uncontrolled before-after design Stuff, K. Kainz, E. Kahl, U. Pinnschmidt, H. Beck, S. von Breunig, F. Nitzschke, R. Funcke, S. Zöllner, C. Fischer, M. Perioper Med (Lond) 2022

Anesthesia
Benzodiazepines
Delirium
Perioperative care
Premedication

Associations of Smoking With Delirium and Opioid Use in Older Adults With Traumatic Hip Fracture Salottolo, K. Meinig, R. Fine, L. Kelly, M. Madayag, R. Ekengren, F. Tanner, A., 2nd Bar-Or, D. J Am Acad Orthop Surg Glob Res Rev 2022

Aged
Analgesics, Opioid/therapeutic use
*Delirium/epidemiology/etiology/prevention & control
*Hip Fractures/epidemiology/etiology/surgery
Humans
*Opioid-Related Disorders/complications/drug therapy
Pain, Postoperative/drug therapy
Prospective Studies
Smoking/adverse effects/epidemiology

Impact of delirium on mortality in patients hospitalized for heart failure Ritchie, C. Walters, R. W. Ramaswamy, S. Alla, V. M. Int J Psychiatry Med 2022

Aged
*Delirium/diagnosis
*Heart Failure/diagnosis/epidemiology
Hospital Mortality
Hospitalization
Humans
Length of Stay
Retrospective Studies
United States/epidemiology
delirium
heart failure
national inpatient sample

Risk for post-operative delirium related to comorbidities in older adult cardiac patients: An integrative review Ramos, M. D. Vergara, F. H. Shackleford, J. Briggs, C. Gomez, C. Mofazali, M. Preston, J. J Clin Nurs 2022

cardiac surgery
comorbidities
older adults
post-operative delirium

Diagnosis and management of delirium in hospital oncology services Ramírez Zuluaga, L. P. Ruano Restrepo, M. I. Osorio Bermúdez, J. D. Díaz Vallejo, J. A. J Geriatr Oncol 2022

*Delirium/diagnosis/etiology/therapy
Humans
*Neoplasms/complications/therapy
Oncology Service, Hospital
Prognosis
*Cancer
*Delirium
*Hospital oncology services

Cognitive Predictors of Delirium on Long-Term Follow-Up after TIA and Stroke: Population-Based Cohort Study Pendlebury, S. T. Thomson, R. J. Welch, S. J. V. Rothwell, P. M. Cerebrovasc Dis 2022

Aged
Cognition
*Cognitive Dysfunction/diagnosis/epidemiology/etiology
Cohort Studies
*Delirium/diagnosis/epidemiology/etiology
Follow-Up Studies
Humans
*Ischemic Attack, Transient/complications/diagnosis/psychology
Neuropsychological Tests
*Stroke/complications/diagnosis
Cognitive impairment
Delirium
Long-term follow-up
TIA and stroke

Plasma neurofilament light chain protein as a predictor of days in delirium and deep sedation, mortality and length of stay in critically ill patients Page, V. J. Watne, L. O. Heslegrave, A. Clark, A. McAuley, D. F. Sanders, R. D. Zetterberg, H. EBioMedicine 2022

Biomarker
Critical care
Delirium
Intensive care
Neurofilament light protein

Feasibility of Machine Learning and Logistic Regression Algorithms to Predict Outcome in Orthopaedic Trauma Surgery Oosterhoff, J. H. F. Gravesteijn, B. Y. Karhade, A. V. Jaarsma, R. L. Kerkhoffs, Gmmj Ring, D. Schwab, J. H. Steyerberg, E. W. Doornberg, J. N. J Bone Joint Surg Am 2022

Algorithms
*Ankle Fractures/surgery
Feasibility Studies
Humans
Logistic Models
Machine Learning
*Orthopedics
Retrospective Studies
*Scaphoid Bone
*Tibial Fractures/surgery

Delirium detection methodologies: Implications for outcome measurement in clinical trials in postoperative delirium Oh, E. S. Rosenberg, P. B. Wang, N. Y. Sieber, F. E. Neufeld, K. J. Int J Geriatr Psychiatry 2022

Aged
*Delirium/epidemiology
Diagnostic and Statistical Manual of Mental Disorders
*Hip Fractures/complications/surgery
Humans
Incidence
Postoperative Complications/diagnosis
*clinical trials
*confusion assessment method (CAM)
*consenus panel diagnosis
*delirium
*hip fracture

Nurse staffing levels are not associated with appearance, duration or solution of delirium in stroke patients Nydahl, P. Meyne, J. Osterbrink, J. Margraf, N. G. Intensive Crit Care Nurs 2022

*Delirium/complications
Humans
*Nurses
*Nursing Staff, Hospital
Personnel Staffing and Scheduling
*Stroke/complications
Workforce
*Delirium
*Encephalopathy
*Personnel Staffing and Scheduling

Regional vs General Anesthesia and Incidence of Postoperative Delirium in Older Patients Undergoing Hip Fracture Surgery Nobuhara, C. Devinney, M., Jr. Berger, M. Jama 2022

Aged
*Anesthesia, Conduction/adverse effects
*Anesthesia, General/adverse effects
*Delirium/epidemiology/etiology
*Hip Fractures/epidemiology/surgery
Humans
Incidence
Postoperative Complications/epidemiology/etiology

Linking Perioperative Medications and Delirium Nathan, N. Anesth Analg 2022

*Delirium/chemically induced/diagnosis
Humans
Perioperative Care
Postoperative Complications
Risk Factors

Prolonged and severe post-electroconvulsive therapy delirium with concurrent clozapine therapy Melnikoff, E. Thomas Johnson, E. Walker, F. Itrat, Q. Jagadheesan, K. Aust N Z J Psychiatry 2022

*Antipsychotic Agents/adverse effects
*Clozapine/adverse effects
Combined Modality Therapy
*Delirium/therapy
*Electroconvulsive Therapy
Humans

'Excited Delirium', acute behavioural disturbance, death and diagnosis McGuinness, T. Lipsedge, M. Psychol Med 2022

Acute behavioural disturbance
coroners
emergency psychiatry
excited delirium
restraints

Effects of non-pharmacologic prevention on delirium in critically ill patients: A network meta-analysis Matsuura, Y. Ohno, Y. Toyoshima, M. Ueno, T. Nurs Crit Care 2022

acute encephalopathy
delirium
intensive care unit
network meta-analysis
systematic review

Melatonin Receptor Agonists for the Prevention of Delirium: An Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials Maneeton, B. Kongsaengdao, S. Maneeton, N. Likhitsathian, S. Woottiluk, P. Kawilapat, S. Srisurapanont, M. Curr Neuropharmacol 2022

Delirium
Incidence
Melatonin
Melatonin Receptor Agonist
Prevention
Ramelteon

Potential Value of Serum Lipid in the Identication of Postoperative Delirium Undergoing Knee/Hip Arthroplasty: The Perioperative Neurocognitive Disorder and Biomarker Lifestyle Study Lin, Y. Peng, X. Lin, X. Deng, X. Liu, F. Tao, H. Dong, R. Wang, B. Bi, Y. Front Psychiatry 2022

cholesterol
delirium
high-density lipoprotein (HDL)
low-density lipoprotein (LDL)
mediation effect
triglycerides (TG)
commercial or financial relationships that could be construed as a potential
conflict of interest.

Habitual tea consumption and postoperative delirium after total hip/knee arthroplasty in elderly patients: The PNDABLE study Lin, X. Li, X. X. Dong, R. Wang, B. Bi, Y. L. Brain Behav 2022

cholinergic nerve system
elderly
hip/knee arthroplasty
postoperative delirium
tea

Delirium and the risk of developing dementia: a cohort study of 12 949 patients Leighton, S. P. Herron, J. W. Jackson, E. Sheridan, M. Deligianni, F. Cavanagh, J. J Neurol Neurosurg Psychiatry 2022

Dementia
Medicine
Memory
Neuropsychiatry
PSYCHOGERIATRICS

Delirium risk factors analysis post proximal femur fracture surgery in elderly Leigheb, M. De Sire, A. Zeppegno, P. Forni, F. Sgreccia, M. Gagliardi, V. P. Pogliacomi, F. Sabbatini, M. Acta Biomed 2022

Aged
*Delirium/complications/etiology
*Femoral Fractures/epidemiology/surgery
Femur
*Hip Fractures/complications/surgery
Humans
Postoperative Complications/epidemiology/etiology
Risk Factors

A Scoping Review of the Incidence, Predictors, and Outcomes of Delirium Among Critically Ill Stroke Patients Lawson, T. N. Balas, M. C. McNett, M. J Neurosci Nurs 2022

Adult
Critical Illness/psychology
*Delirium/epidemiology/etiology
Humans
Incidence
Intensive Care Units
*Ischemic Stroke
Quality of Life
*Subarachnoid Hemorrhage/complications

Non-Pharmacological Nursing Interventions to Prevent Delirium in ICU Patients-An Umbrella Review with Implications for Evidence-Based Practice Lange, S. Mędrzycka-Dąbrowska, W. Friganovic, A. Oomen, B. Krupa, S. J Pers Med 2022

Icu
delirium
non-pharmacological interventions
systematic review

A decision tree prediction model for a short-term outcome of delirium in patients with advanced cancer receiving pharmacological interventions: A secondary analysis of a multicenter and prospective observational study (Phase-R) Kurisu, K. Inada, S. Maeda, I. Ogawa, A. Iwase, S. Akechi, T. Morita, T. Oyamada, S. Yamaguchi, T. Imai, K. Nakahara, R. Kaneishi, K. Nakajima, N. Sumitani, M. Yoshiuchi, K. Palliat Support Care 2022

Decision Trees
*Delirium/complications/etiology
Humans
*Neoplasms/complications/drug therapy
Palliative Care
Prospective Studies
*Cancer
*Delirium
*Machine learning
*Palliative care
*Psycho-oncology

Postoperative delirium is an independent factor influencing the length of stay of elderly patients in the intensive care unit and in hospital Kirfel, A. Guttenthaler, V. Mayr, A. Coburn, M. Menzenbach, J. Wittmann, M. J Anesth 2022

Aged
Aged, 80 and over
*Delirium/diagnosis/epidemiology/etiology
Hospitals, University
Humans
Intensive Care Units
Length of Stay
*Postoperative Complications/epidemiology/therapy
Risk Factors
Elderly patients
Postoperative delirium

Cost-effectiveness of clinical interventions for delirium: A systematic literature review of economic evaluations Kinchin, I. Edwards, L. Hosie, A. Agar, M. Mitchell, E. Trepel, D. Acta Psychiatr Scand 2022

cost-effectiveness
delirium
economic evaluation
intervention
quality of evidence
review

Effects of non-pharmacological interventions for preventing delirium in general ward inpatients: A systematic review & meta-analysis of randomized controlled trials Kim, Y. H. Kim, N. Y. Ryu, S. PLoS One 2022

Adult
*Delirium/epidemiology/prevention & control
Hospitalization
Humans
*Inpatients
Patients’ Rooms
Randomized Controlled Trials as Topic

Analysis of the Incidence and Risk Factors of Postoperative Delirium in Patients With Degenerative Cervical Myelopathy Kim, N. Kim, T. H. Oh, J. K. Lim, J. Lee, K. U. Kim, S. W. Neurospine 2022

Cervical myelopathy
Delirium
Laminoplasty
Postoperative care

Intraoperative low tidal volume ventilation and the risk of ICD-10 coded delirium and the use for antipsychotic medications Karalapillai, D. Weinberg, L. Neto, A. S. Peyton, P. J. Ellard, L. Hu, R. Pearce, B. Tan, C. Story, D. O'Donnell, M. Hamilton, P. Oughton, C. Galtieri, J. Appu, S. Wilson, A. Eastwood, G. Bellomo, R. Jones, D. A. BMC Anesthesiol 2022

Adult
Aged
*Antipsychotic Agents/adverse effects
*Delirium/chemically induced/epidemiology
Female
Humans
International Classification of Diseases
Male
Middle Aged
Positive-Pressure Respiration/adverse effects
Postoperative Complications/epidemiology/etiology
Respiration, Artificial
Tidal Volume
Delirium
Postoperative
Surgery
Tidal volume

Falling for It: Of Falls, Families, and Delirium Jiménez, J. V. Hyzy, R. C. Crit Care Med 2022

*Accidental Falls
*Delirium/epidemiology/etiology
Fear
Humans

Safety and Effectiveness of Perospirone in Comparison to Risperidone for Treatment of Delirium in Patients with Advanced Cancer: A Multicenter Prospective Observational Study in Real-World Psycho-Oncology Settings Inoue, S. Maeda, I. Ogawa, A. Yoshiuchi, K. Terada, S. Yamada, N. Acta Med Okayama 2022

Aged
*Antipsychotic Agents/adverse effects
*Delirium/chemically induced/etiology
Humans
Isoindoles
*Neoplasms/complications/drug therapy
Psycho-Oncology
Risperidone/adverse effects
Thiazoles
cancer
delirium
perospirone
risperidone

Higher Grade Glioma Increases the Risk of Postoperative Delirium: Deficient Brain Compensation Might Be a Potential Mechanism of Postoperative Delirium Huang, H. W. Zhang, X. K. Li, H. Y. Wang, Y. G. Jing, B. Chen, Y. Patel, M. B. Ely, E. W. Liu, Y. O. Zhou, J. X. Lin, S. Zhang, G. B. Front Aging Neurosci 2022

brain cognitive compensation
conceptual model
frontal lobe glioma
postoperative delirium
structural and functional MRI

Fluconazole-induced delirium in an older patient with schizophrenia Hu, T. M. Wu, C. L. Psychogeriatrics 2022
Knowledge assessment is key to identifying the training needs of delirium care Ho, M. H. Intensive Crit Care Nurs 2022

*Delirium/nursing/therapy
Humans
*Intensive Care Units

Anticholinergic Drug Exposure Increases the Risk of Delirium in Older Patients Undergoing Elective Surgery Herrmann, M. L. Boden, C. Maurer, C. Kentischer, F. Mennig, E. Wagner, S. Conzelmann, L. O. Förstner, B. R. Rapp, M. A. von Arnim, C. A. F. Denkinger, M. Eschweiler, G. W. Thomas, C. Front Med (Lausanne) 2022

acute encephalopathy
anticholinergic
delirium
geriatric
postoperative
surgery

A prediction model for delirium after cardiac surgery: Another step towards prevention? Herman, J. A. Urman, R. D. Urits, I. Kaye, A. D. Viswanath, O. J Clin Anesth 2022

*Cardiac Surgical Procedures/adverse effects
*Delirium/etiology/prevention & control
Humans
Postoperative Complications/etiology/prevention & control
Risk Factors

The effect of a dexmedetomidine infusion on delirium in the ICU Herman, J. A. Urman, R. D. Urits, I. Kaye, A. D. Viswanath, O. J Clin Anesth 2022

*Delirium/chemically induced/drug therapy
*Dexmedetomidine/adverse effects
Humans
Hypnotics and Sedatives/adverse effects
Intensive Care Units

Which interventions can reduce post-operative delirium in the elderly? Synthesis of multidisciplinary and pharmacological intervention data Herman, J. Urman, R. D. Urits, I. Kaye, A. D. Viswanath, O. J Clin Anesth 2022

Aged
*Delirium/etiology/prevention & control
Humans
Postoperative Complications/etiology/prevention & control

What is the impact of perioperative cerebral oxygen desaturation on postoperative delirium in old population: a systemic review and meta-analysis He, K. Q. Wang, S. Zhang, W. Liu, Q. Chai, X. Q. Aging Clin Exp Res 2022

Cerebral oxygen saturation
Meta-analysis
Old population
Postoperative delirium
Preoperative monitoring

Midazolam and delirium: can you have it both ways? Greengrass, R. A. Reg Anesth Pain Med 2022

*Delirium/chemically induced/diagnosis
Humans
Hypnotics and Sedatives/adverse effects
*Midazolam/adverse effects
drug-related side effects and adverse reactions
pharmacology
postoperative complications

Music Interventions and Delirium in Adults: A Systematic Literature Review and Meta-Analysis Golubovic, J. Neerland, B. E. Aune, D. Baker, F. A. Brain Sci 2022

acute confusion
delirium
meta-analysis
music interventions
music therapy
prevention
systematic review
treatment

In older adults having hip fracture surgery, regional vs. general anesthesia did not reduce postoperative delirium Gill, S. S. Ann Intern Med 2022

Aged
Anesthesia, General/adverse effects
*Delirium/prevention & control
*Hip Fractures/epidemiology/surgery
Humans
Incidence
Postoperative Complications/epidemiology/prevention & control

Relationship between preoperative anxiety and onset of delirium after cardiovascular surgery in elderly patients: focus on personality and coping process Fukunaga, H. Sugawara, H. Koyama, A. Okamoto, K. Fukui, T. Ishikawa, T. Takebayashi, M. Sekiyama, K. Hashimoto, M. Psychogeriatrics 2022

agreeableness
anxiety
delirium
personality

Identifying Delirium in Persons With Moderate or Severe Dementia: Review of Challenges and an Illustrative Approach Fong, T. G. Hshieh, T. T. Tabloski, P. A. Metzger, E. D. Arias, F. Heintz, H. L. Patrick, R. E. Lapid, M. I. Schmitt, E. M. Harper, D. G. Forester, B. P. Inouye, S. K. Am J Geriatr Psychiatry 2022

Advanced dementia
Ect
delirium
delirium superimposed on dementia

Depression is associated with delirium after cardiac surgery - A population-based cohort study Falk, A. Kåhlin, J. Nymark, C. Hultgren, R. Stenman, M. Interact Cardiovasc Thorac Surg 2022

Cardiac surgery
Phq-9
depression
postoperative delirium
risk factors
screening

Incidence, characteristics and risk factors of delirium in the intensive care unit: An observational study Erbay Dalli, Ö Kelebek Girgin, N. Kahveci, F. J Clin Nurs 2022

critically ill
delirium
incidence
intensive care unit
risk factors

Incidence, characteristics and risk factors of delirium in the intensive care unit: An observational study Erbay Dalli, Ö Kelebek Girgin, N. Kahveci, F. J Clin Nurs 2022

critically ill
delirium
incidence
intensive care unit
risk factors

Association Between Perioperative Medication Use and Postoperative Delirium and Cognition in Older Adults Undergoing Elective Noncardiac Surgery Duprey, M. S. Devlin, J. W. Griffith, J. L. Travison, T. G. Briesacher, B. A. Jones, R. Saczynski, J. S. Schmitt, E. M. Gou, Y. Marcantonio, E. R. Inouye, S. K. Anesth Analg 2022

Aged
Analgesics, Opioid
*Antipsychotic Agents
Benzodiazepines
Cognition
*Delirium/chemically induced/diagnosis/epidemiology
Humans
Postoperative Complications/diagnosis/epidemiology/etiology
Prospective Studies
Risk Factors

Comparison of incidence of emergence delirium in pediatric patients with three different techniques of general anesthesia using sevoflurane and propofol: a randomized controlled trial Deepak, M. Shilpa, G. Nikhil, K. Ankur, S. Rakesh, K. Swati, C. Akhil, G. Pradeep, B. Braz J Anesthesiol 2022
Delirium and long-term psychopathology following surgery in older adults de Mul, N. van den Bos, Lmec Kant, I. M. J. van Montfort, S. J. T. Schellekens, W. M. Cremer, O. L. Slooter, A. J. C. J Psychosom Res 2022

Aged
Anxiety/epidemiology
*Delirium/diagnosis/epidemiology/etiology
Humans
Male
Postoperative Complications/diagnosis/epidemiology/etiology
Risk Factors
*Stress Disorders, Post-Traumatic/diagnosis/epidemiology/etiology
Anxiety and PTSS
Depression
Elderly
Postoperative delirium
Postoperative psychopathology

Study protocol to test the efficacy of self-administration of dexmedetomidine sedative therapy on anxiety, delirium, and ventilator days in critically ill mechanically ventilated patients: an open-label randomized clinical trial Chlan, L. L. Weinert, C. R. Tracy, M. F. Skaar, D. J. Gajic, O. Ask, J. Mandrekar, J. Trials 2022

Aftercare
Analgesics, Opioid
Anxiety/diagnosis/therapy
*covid-19
Critical Illness
*Delirium/diagnosis/drug therapy/etiology
*Dexmedetomidine/adverse effects
Humans
Hypnotics and Sedatives/adverse effects
Intensive Care Units
Pandemics
Patient Discharge
Quality of Life
Randomized Controlled Trials as Topic
Respiration, Artificial/adverse effects/methods
Ventilators, Mechanical
Anxiety
Clinical trial
Intensive care
Mechanical ventilation
Sedation

Corticosteroids in patients undergoing cardiac surgery: A meta-analysis of 12,559 patients Chen, L. Xiang, F. Hu, Y. Perfusion 2022

cardiac surgery
corticosteroid
in-hospital mortality
meta-analysis
randomized controlled trial

Postoperative outcomes in older surgical patients with preoperative cognitive impairment: A systematic review and meta-analysis Chen, L. Au, E. Saripella, A. Kapoor, P. Yan, E. Wong, J. Tang-Wai, D. F. Gold, D. Riazi, S. Suen, C. He, D. Englesakis, M. Nagappa, M. Chung, F. J Clin Anesth 2022

Cognitive impairment
Delirium
Dementia
Older adults
Postoperative complications
Surgery

Benzodiazepine-Based Sedation Did Not Add an Independent Risk of Delirium? Cai, X. Gao, R. Zhang, S. Chen, C. Crit Care Med 2022

*Benzodiazepines/adverse effects
*Delirium/drug therapy
Humans
Hypnotics and Sedatives/adverse effects
Intensive Care Units
interest.

Natural language processing and detecting delirium Burki, T. Lancet Respir Med 2022
Delirium risk factors in hospitalized patient: a comprehensive evaluation of underlying diseases and medications in different wards of a large Urban Hospital Center in Iran Arbabi, M. Ziaei, E. Amini, B. Ghadimi, H. Rashidi, F. Shohanizad, N. Moradi, S. Beikmarzehei, A. Hasanzadeh, A. Parsaei, A. BMC Anesthesiol 2022

*Delirium/epidemiology
Hospitals, Urban
Humans
Iran/epidemiology
Prospective Studies
Risk Factors
Confusion
Delirium
Dementia
Hospitalization
Neoplasms
Neurological diseases
research.

Depression and anxiety increase the odds of developing delirium in ICU patients; a prospective observational study Arbabi, M. Dezhdar, Z. Amini, B. Dehnavi, A. Z. Ghasemi, M. Cogn Neuropsychiatry 2022

Anxiety
*Delirium/complications/diagnosis/epidemiology
Depression
Humans
Intensive Care Units
Vision Disorders/complications
*Depression
*hads
*icu
*anxiety
*delirium

Andersen-Ranberg, N. Poulsen, L. M. Perner, A. Hästbacka, J. Morgan, M. P. G. Citerio, G. Oxenbøll-Collet, M. Weber, S. O. Andreasen, A. S. Bestle, M. H. Uslu, B. Pedersen, H. B. S. Nielsen, L. G. Damgaard, K. Jensen, T. B. Sommer, T. Dey, N. Mathiesen, Agents intervening against delirium in the intensive care unit trial-Protocol for a secondary Bayesian analysis Acta Anaesthesiol Scand 2022

Bayesian statistics
Delirium
Icu
haloperidol

Sleep monitoring challenges in patients with neurocognitive disorders: A cross-sectional analysis of missing data from activity trackers Ahuja, M. Siddhpuria, S. Reppas-Rindlisbacher, C. Wong, E. Gormley, J. Lee, J. Patterson, C. Health Sci Rep 2022

activity monitor
delirium
dementia
hospitalized older adults
neurocognitive disorder

The Dilemma of Treating Delirium: the Conundrum of Drug Management Agar, M. R. Amgarth-Duff, I. Curr Treat Options Oncol 2022

Antipsychotics
Benzodiazepines
Delirium
Palliative care
Treatment

Gabapentinoid Use Is Associated With Reduced Occurrence of Hyperactive Delirium in Older Cancer Patients Undergoing Chemotherapy: A Nationwide Retrospective Cohort Study in Japan Abe, H. Sumitani, M. Matsui, H. Inoue, R. Konishi, M. Fushimi, K. Uchida, K. Yasunaga, H. Anesth Analg 2022

Gabapentinoid Use Is Associated With Reduced Occurrence of Hyperactive Delirium in Older Cancer Patients Undergoing Chemotherapy: A Nationwide Retrospective Cohort Study in Japan

Incidence, predictors and health outcomes of delirium in very old hospitalized patients: a prospective cohort study Zhang, M. Zhang, X. Gao, L. Yue, J. Jiang, X. BMC Geriatr 2022

Aged
Aged, 80 and over
*Delirium/diagnosis/epidemiology/etiology
Hospitalization
Humans
Incidence
Outcome Assessment, Health Care
Prospective Studies
Cognitive impairment
Delirium
Prediction model
Risk factor
Very old patients

The effect of delirium information training given to intensive care nurses on patient care: quasi-experimental study Yıldırım, F. Türkleş, S. Altundal Duru, H. PeerJ 2022

Checklist
Delirium
Intensive care unit
Nursing
Patient care
Training

Mechanical Bowel Preparation Is a Risk Factor for Postoperative Delirium as It Alters the Gut Microbiota Composition: A Prospective Randomized Single-Center Study Yang, Z. Tong, C. Qian, X. Wang, H. Wang, Y. Front Aging Neurosci 2022

gastrectomy
gut microbiota
mechanical bowel preparation (MBP)
perioperative interventions
postoperative delirium (POD)
commercial or financial relationships that could be construed as a potential
conflict of interest.

The Mini-Cog: A simple screening tool for cognitive impairment useful in predicting the risk of delirium after major urological cancer surgery Yajima, S. Nakanishi, Y. Matsumoto, S. Ookubo, N. Tanabe, K. Kataoka, M. Masuda, H. Geriatr Gerontol Int 2022

Activities of Daily Living
*Cognitive Dysfunction/psychology
*Delirium/diagnosis/etiology/psychology
Early Detection of Cancer
Humans
Mental Status and Dementia Tests
Risk Factors
*Urologic Neoplasms/complications/diagnosis/surgery
cognitive dysfunction
delirium
dementia
robotic surgery
urology

A Novel Radiomics-Based Machine Learning Framework for Prediction of Acute Kidney Injury-Related Delirium in Patients Who Underwent Cardiovascular Surgery Xue, X. Chen, W. Chen, X. Comput Math Methods Med 2022

*Acute Kidney Injury/diagnostic imaging/etiology
*Delirium/diagnostic imaging/etiology
Humans
Machine Learning
Retrospective Studies
Support Vector Machine

The Effect of Preoperative Methylprednisolone on Postoperative Delirium in Older Patients Undergoing Gastrointestinal Surgery: A Randomized, Double-Blind, Placebo-Controlled Trial Xiang, X. B. Chen, H. Wu, Y. L. Wang, K. Yue, X. Cheng, X. Q. J Gerontol A Biol Sci Med Sci 2022

Aged
Brain-Derived Neurotrophic Factor
*Delirium/epidemiology/etiology/prevention & control
*Digestive System Surgical Procedures/adverse effects
Double-Blind Method
Heparitin Sulfate
Humans
Methylprednisolone/therapeutic use
Postoperative Complications/epidemiology/prevention & control
Syndecan-1
Tumor Necrosis Factor-alpha
*Brain-derived neurotrophic factor
*Delirium
*Heparan sulfate
*Methylprednisolone
*Syndecan-1
*Tumor necrosis factor-α

Head-to-head comparison of 14 prediction models for postoperative delirium in elderly non-ICU patients: an external validation study Wong, C. K. van Munster, B. C. Hatseras, A. Huis In 't Veld, E. van Leeuwen, B. L. de Rooij, S. E. Pleijhuis, R. G. BMJ Open 2022

Aged
*Delirium/diagnosis/etiology/prevention & control
Humans
Prospective Studies
delirium & cognitive disorders
geriatric medicine
internal medicine
risk management
surgery

Impact of a dementia-friendly program on detection and management of patients with cognitive impairment and delirium in acute-care hospital units: a controlled clinical trial design Weldingh, N. M. Mellingsæter, M. R. Hegna, B. W. Benth, J. S. Einvik, G. Juliebø, V. Thommessen, B. Kirkevold, M. BMC Geriatr 2022

Aged
Aged, 80 and over
Clinical Trials as Topic
*Cognitive Dysfunction/diagnosis/therapy
*Delirium/diagnosis/psychology/therapy
*Dementia/diagnosis/psychology/therapy
Hospital Units
Humans
Cognitive impairment
Delirium
Delirium detection
Delirium prevention
Delirium screening
Delirium treatment measures
Dementia-friendly hospital
Implementation

Influence of Patient-Specific Covariates on Test Validity of Two Delirium Screening Instruments in Neurocritical Care Patients (DEMON-ICU) Weiss, B. Paul, N. Spies, C. D. Ullrich, D. Ansorge, I. Salih, F. Wolf, S. Luetz, A. Neurocrit Care 2022

Critical Care/methods
*Delirium/diagnosis
Humans
Intensive Care Units
*Ischemic Attack, Transient
Reproducibility of Results
*Stroke/complications/diagnosis
*cam-icu
*Critical care
*Delirium
*Hypnotics and sedatives
*icdsc
*Neurocritical care
*Sensitivity
*Specificity

Development and Validation of a Postoperative Delirium Prediction Model for Elderly Orthopedic Patients in the Intensive Care Unit Wang, G. Zhang, L. Qi, Y. Chen, G. Zhou, J. Zhu, H. Hao, Y. J Healthc Eng 2022

Aged
Critical Care
*Delirium/diagnosis/etiology/prevention & control
Humans
Intensive Care Units
Prospective Studies
ROC Curve

Effects of Atorvastatin Therapy on Postoperative Delirium After Malignant Tumor Surgeries in Older Adults Wan, R. Cai, S. Pan, D. Yang, W. Zhou, R. Neuropsychiatr Dis Treat 2022

30-day all-cause mortality
Rct
atorvastatin
outcome
postoperative delirium

Psychometric Properties of a Delirium Severity Score for Older Adults and Association With Hospital and Posthospital Outcomes Vasunilashorn, S. M. Fong, T. G. Helfand, B. K. I. Hshieh, T. T. Marcantonio, E. R. Metzger, E. D. Schmitt, E. M. Tabloski, P. A. Travison, T. G. Gou, Y. Jones, R. N. Inouye, S. K. JAMA Netw Open 2022

Aged
Aged, 80 and over
*Delirium/diagnosis/therapy
Female
Hospitals
Humans
Prospective Studies
Psychometrics
Reproducibility of Results

Delirium can be safely managed in the community through implementation of a community toolkit: a proof-of-concept pilot study Vardy, E. Roberts, S. Pratt, H. Future Healthc J 2022

assessment
community
delirium
management
pilot

Delirium as a Presenting Symptom of COVID-19 Tyson, B. Shahein, A. Erdodi, L. Tyson, L. Tyson, R. Ghomi, R. Agarwal, P. Cogn Behav Neurol 2022
The effect of baseline cognition and delirium on long-term cognitive impairment and mortality: a prospective population-based study Tsui, A. Searle, S. D. Bowden, H. Hoffmann, K. Hornby, J. Goslett, A. Weston-Clarke, M. Howes, L. H. Street, R. Perera, R. Taee, K. Kustermann, C. Chitalu, P. Razavi, B. Magni, F. Das, D. Kim, S. Chaturvedi, N. Sampson, E. L. Rockwood, K. Cunningham, C. E Lancet Healthy Longev 2022
Delirium with visual hallucinations induced by low-dose olanzapine Takeuchi, N. Makino, T. Nishihara, M. Psychogeriatrics 2022

*Antipsychotic Agents/adverse effects
Benzodiazepines/adverse effects
*Delirium/chemically induced/drug therapy
Hallucinations/chemically induced/drug therapy
Humans
Olanzapine/adverse effects