Delirium Bibliography

Delirium Bibliography books graphicWhat is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!

How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.

Reference Information

Title
Risk factors for postoperative delirium in frail elderly patients undergoing on-pump cardiac surgery and development of a prediction model-a prospective observational study
Authors
Ding, Y. Gao, J. Ge, Y. Huang, T. Zhang, Y.
Year
2024
Journal
Front Cardiovasc Med
Abstract

BACKGROUND: To identify the risk factors for postoperative delirium (POD) after cardiac surgery in frail elderly patients and develop a receiver operating characteristic (ROC) prediction model to confirm the effectiveness. METHODS: This was a prospective observational study, patients were assessed preoperatively according to the frailty index (FI) scale. Cerebral (SctO(2)) was assessed at different time points using near-infrared spectroscopy (NIRS). On the basis of the occurrence of POD within 7 days after surgery, patients were divided into POD and non-POD groups. Risk factors were analyzed using logistic regression analysis, while their predictive values were evaluated using the receiver operating characteristic curve analysis. RESULTS: POD was significantly associated with frailty, lower preoperative MMSE scores, hyperlipidemia, diabetes, cerebrovascular disease, lower hemoglobin level, lower albumin level, longer operation time, longer CPB time, lower SctO(2) at T5, and lower SctO(2baseline) (P < 0.05). SrtO(2) and SmtO(2) did not differ significantly between groups. FI, preoperative MMSE score, and operation time as independent risk factors (P < 0.05). Significant predictive value was demonstrated in all 3 variables (P < 0.001; respectively). Among them, high sensitivity and specificity were observed with the FI (cut-off value 0.27, sensitivity 75%, specificity 73.5%) and operation time (cut-off value 237.5, sensitivity 62.5%, specificity 78.6%). CONCLUSIONS: The FI, preoperative MMSE score, and operation time were independent risk factors for POD in elderly patients after cardiac surgery, with high predictive value observed with the FI and operation time. Cerebral oxygen saturation was associated with POD but was not an independent risk factor. CLINICAL TRIAL REGISTRATION: Chinese Clinical Trail Registry, No: chictr2200056038.

PMID

PMID: 39171326

PMCID: PMC11335481

Keywords

cardiac surgery
cardiopulmonary bypass
frailty
near-infrared spectroscopy
postoperative delirium
tissue oxygen saturation

Page(s)
Issue

Search:
Total Records Found: 6347, showing 100 per page
TitleAuthorsJournalYearKeywords
Delirium severity does not differ between medical and surgical intensive care units after adjusting for medication use Ortiz, D. Lindroth, H. L. Braly, T. Perkins, A. J. Mohanty, S. Meagher, A. D. Khan, S. H. Boustani, M. A. Khan, B. A. Sci Rep 2022

Activities of Daily Living
Adolescent
Adult
Analgesics, Opioid/therapeutic use
Benzodiazepines/therapeutic use
Consciousness Disorders/complications
Critical Care
*Delirium/drug therapy/etiology
Female
Humans
Intensive Care Units
Male
Middle Aged

Risk factors for postoperative delirium on oxygen delivery-guided perfusion Mukaida, H. Matsushita, S. Minami, Y. Sato, G. Usuba, M. Kondo, R. Asai, T. Amano, A. J Cardiothorac Surg 2022

Cardiopulmonary Bypass/adverse effects/methods
*Delirium/etiology/prevention & control
Humans
Oxygen
Perfusion/adverse effects
*Postoperative Complications/etiology/prevention & control
Retrospective Studies
Risk Factors
Cardiopulmonary bypass
Goal directed perfusion
Hemodilution
Optimal perfusion
Oxygen delivery

Identifying Medicare Beneficiaries With Delirium Moura, Lmvr Zafar, S. Benson, N. M. Festa, N. Price, M. Donahue, M. A. Normand, S. L. Newhouse, J. P. Blacker, D. Hsu, J. Med Care 2022
The development of a web-based app employing machine learning for delirium prevention in long-term care facilities in South Korea Moon, K. J. Son, C. S. Lee, J. H. Park, M. BMC Med Inform Decis Mak 2022

*Delirium/diagnosis/prevention & control
Humans
Internet
Long-Term Care
Machine Learning
*Mobile Applications
Republic of Korea
Clinical decision support system
Delirium
Long-term care facility
Mobile apps
Rule-based prediction

Impact of Family Presence on Delirium in Critically Ill Patients: A Retrospective Cohort Study Mohsen, S. Moss, S. J. Lucini, F. Krewulak, K. D. Stelfox, H. T. Niven, D. J. Sauro, K. M. Fiest, K. M. Crit Care Med 2022
Serum levels of apolipoprotein A-I and E are associated with postoperative delirium: A post hoc analysis Mietani, K. Hasegawa-Moriyama, M. Inoue, R. Ogata, T. Shimojo, N. Kurano, M. Yatomi, Y. Uchida, K. Sumitani, M. Medicine (Baltimore) 2022

Aged
*Apolipoprotein A-I
Biomarkers
*Delirium/diagnosis/etiology/psychology
Humans
Postoperative Complications/diagnosis
Prospective Studies
Risk Factors

Staff training and the use of rapid, accurate and user-friendly tools for delirium screening could improve the diagnosis of delirium in the elderly referred to the emergency department Mazzola, P. Spedale, V. Evid Based Nurs 2022

evidence-based nursing
mental health
nursing
nursing research

Current practice of pharmacological treatment for hyperactive delirium in terminally ill cancer patients: results of a nationwide survey of Japanese palliative care physicians and liaison psychiatrists Matsuda, Y. Morita, T. Oya, K. Tagami, K. Naito, A. S. Kashiwagi, H. Otani, H. Jpn J Clin Oncol 2022

*Antipsychotic Agents/therapeutic use
Benzodiazepines/therapeutic use
*Delirium/drug therapy
Haloperidol/therapeutic use
Humans
Japan
*Neoplasms/complications/drug therapy
Palliative Care
*Physicians
*Psychiatry
Surveys and Questionnaires
Terminally Ill
antipsychotic
cancer
hyperactive delirium
pharmacological treatment
terminal delirium

Higher serum PGE2 is a predicative biomarker for postoperative delirium following elective orthopedic surgery in elderly patients Mao, M. Wang, L. Y. Zhu, L. Y. Wang, F. Ding, Y. Tong, J. H. Sun, J. Sun, Q. Ji, M. H. BMC Geriatr 2022

Aged
Biomarkers
*Delirium/diagnosis/epidemiology/etiology
Dinoprostone
Humans
*Orthopedic Procedures/adverse effects
Postoperative Complications/diagnosis/epidemiology/etiology
Prospective Studies
Risk Factors
Biomarker
Orthopedic surgery
Pge2
Postoperative delirium

Effect of acute pain on the association between preoperative cognitive impairment and postoperative delirium: a secondary analysis of three trials Ma, J. H. Liu, Y. F. Hong, H. Li, C. J. Cui, F. Mu, D. L. Wang, D. X. Br J Anaesth 2022

cognitive dysfunction
delirium
mediation analysis
postoperative complications
postoperative pain

A systematic review of modified electroconvulsive therapy (ECT) to treat delirium Lupke, K. Warren, N. Teodorczuk, A. Steele, S. Kolur, U. Wand, A. Robinson, G. Parker, S. Acta Psychiatr Scand 2022

acute confusion
delirium
electroconvulsive therapy
treatment

Incidence and interaction factors of delirium as an independent risk of mortality in elderly patients in the intensive units: a retrospective analysis from MIMIC-IV database Liu, H. Zhao, Q. Liu, X. Hu, X. Wang, L. Zhou, F. Aging Clin Exp Res 2022

Delirium
Elderly patients
Hemoglobin
Mortality
Sofa

The effect of neostigmine on postoperative delirium after colon carcinoma surgery: a randomized, double-blind, controlled trial Liu, F. Lin, X. Lin, Y. Deng, X. Guo, Y. Wang, B. Dong, R. Bi, Y. BMC Anesthesiol 2022

Adult
Aged
Aged, 80 and over
*Carcinoma
Colon
*Delirium/epidemiology/etiology/prevention & control
Double-Blind Method
Humans
Middle Aged
Neostigmine/therapeutic use
Postoperative Complications/epidemiology/prevention & control
Retrospective Studies
Colon carcinoma surgery
Neostigmine
Postoperative delirium
Postoperative pulmonary complications
Tof

Outcomes of postoperative delirium in patients undergoing cardiac surgery: A systematic review and meta-analysis Lin, L. Zhang, X. Xu, S. Peng, Y. Li, S. Huang, X. Chen, L. Lin, Y. Front Cardiovasc Med 2022

cardiac surgery
meta-analysis
mortality
outcome
postoperative delirium
systematic review

Non-pharmacological delirium prevention practices among critical care nurses: a qualitative study Liang, S. Chau, J. P. C. Lo, S. H. S. Zhao, J. Liu, W. BMC Nurs 2022

Delirium
Intensive care units
Non-pharmacological delirium prevention practice
Registered nurses

Effect of regional anesthesia on the postoperative delirium: A systematic review and meta-analysis of randomized controlled trials Li, T. Dong, T. Cui, Y. Meng, X. Dai, Z. Front Surg 2022

delirium
general anesthesia
meta—analysis
pain
regional anesthesia

Assessing Delirium at Hospital Discharge Lepkowsky, C. M. Janklow, H. M. Am J Geriatr Psychiatry 2022

Delirium
assessment
hospital discharge
older adults

The Effects of Pain, Agitation, Delirium, Immobility, and Sleep Disruption Education on Novice Nurses in Adult Intensive Care Units Lee, S. Y. Liu, C. Y. Wu, T. Y. Healthcare (Basel) 2022

Padis
adult intensive care unit
clinical ladder
education intervention
novice nurse

Treatment of Positive Urine Cultures at End-of-Life and the Effect on Terminal Delirium Management Latuga, N. M. Grant, P. C. Levy, K. Luczkiewicz, D. L. Am J Hosp Palliat Care 2022

Anti-Bacterial Agents/therapeutic use
Death
*Delirium/drug therapy
Humans
Palliative Care
Retrospective Studies
*Urinary Tract Infections/drug therapy
antibiotics
antimicrobial
delirium
end-of-life
hospice
infection
palliative
terminal

Risk factors and effect of postoperative delirium on adverse surgical outcomes in older adults after elective abdominal cancer surgery in Taiwan Lai, C. C. Liu, K. H. Tsai, C. Y. Hsu, J. T. Hsueh, S. W. Hung, C. Y. Chou, W. C. Asian J Surg 2022

Cancer surgery
Delirium
Elderly
Oncogeriatric patient
Taiwan

A Quality Improvement Study on Delirium Awareness Day: In Pursuit of Missed Delirium Diagnoses Koca, M. Öztürk, Y. Boğa, İ Bürkük, S. Eşme, M. Akyürek, Y. Şimşek, S. Aydın, D. D. Çiçek, F. Karabulut, E. Halil, M. Cankurtaran, M. Tanrıöver, M. D. Doğu, B. B. J Gerontol Nurs 2022

Aged
*Delirium/diagnosis/epidemiology
Humans
Mass Screening
Prospective Studies
Quality Improvement

Serum C-reactive protein adds predictive information for post-stroke delirium: The PROPOLIS study Klimiec-Moskal, E. Slowik, A. Dziedzic, T. Acta Psychiatr Scand 2022

Crp
delirium
prediction
stroke

External validation and comparison of two delirium prediction models in patients admitted to the cardiac intensive care unit Kim, S. E. Ko, R. E. Na, S. J. Chung, C. R. Choi, K. H. Kim, D. Park, T. K. Lee, J. M. Song, Y. B. Choi, J. O. Hahn, J. Y. Choi, S. H. Gwon, H. C. Yang, J. H. Front Cardiovasc Med 2022

Early PREdiction of DELIRium
PREdiction of DELIRium
cardiac intensive care unit
delirium prediction
prediction model

Delirium and Cortical Complexity Kim, H. Lee, U. C. Vlisides, P. E. Delirium and Cortical Complexity 2022
Can Variables From the Electronic Health Record Identify Delirium at Bedside? Khan, A. Heslin, K. Simpson, M. Malone, M. L. J Patient Cent Res Rev 2022

delirium
diagnosis
disease prediction model
electronic health record
ethnoracial

Thoracic Paravertebral Block Ameliorates Postoperative Delirium in Geriatric Patients Heng, L. Wang, M. Wang, M. Li, L. Zhu, S. Thorac Cardiovasc Surg 2022

Aged
*Delirium/diagnosis/etiology/prevention & control
Humans
Nausea
Pain, Postoperative/diagnosis/etiology/prevention & control
*Propofol/adverse effects
*Pulmonary Atelectasis
Remifentanil
Treatment Outcome
Vomiting

Relationship of sleep disturbance and postoperative delirium: a systematic review and meta-analysis He, E. Dong, Y. Jia, H. Yu, L. Gland Surg 2022

Postoperative delirium (PD)
meta-analysis
sleep disturbance
systematic review

Acceptability of transdermal antipsychotic patches by patients who refuse oral medication and their effectiveness in preventing recurrence of delirium: a retrospective observational study Hatta, K. Usui, C. Nakamura, H. Int Clin Psychopharmacol 2022
Perioperative Hemodynamic Optimization in Patients at Risk for Delirium - A Randomized-Controlled Trial Fuest, K. E. Servatius, A. Ulm, B. Schaller, S. J. Jungwirth, B. Blobner, M. Schmid, S. Front Med (Lausanne) 2022

frailty
goal-directed hemodynamic monitoring
goal-directed therapy
outcome
post-operative delirium

Proposing a Scientific and Technological Approach to the Summaries of Clinical Issues of Inpatient Elderly with Delirium: A Viewpoint Frisardi, V. Nicolini, M. Cautero, N. Ghirardelli, R. Davolio, F. Haouili, M. Barani, M. Healthcare (Basel) 2022

delirium
disease management
healthcare
patient care management
technology
telemedicine

Incidence of Drug-Induced Delirium During Treatment With Antidepressants or Antipsychotics: A Drug Surveillance Report of German-Speaking Countries Between 1993 and 2016 Friedrich, M. E. Grohmann, R. Rabl, U. Winkler, D. Konstantinidis, A. Engel, R. Seifert, J. Toto, S. Stübner, S. Frey, R. Kasper, S. Int J Neuropsychopharmacol 2022

Adverse Drug Reaction Reporting Systems
Amitriptyline
Antidepressive Agents/adverse effects
*Antipsychotic Agents/adverse effects
*Clozapine
*Delirium/chemically induced/drug therapy/epidemiology
Humans
Incidence
Muscarinic Antagonists
*Psychoses, Substance-Induced
Adverse drug reactions
antidepressants
antipsychotics
delirium
drug surveillance

The inter-relationship between delirium and dementia: the importance of delirium prevention Fong, T. G. Inouye, S. K. Nat Rev Neurol 2022
Five-Year Outcomes After Implementing a Pain, Agitation, and Delirium Protocol in a Mixed Intensive Care Unit Fish, J. T. Baxa, J. T. Draheim, R. R. Willenborg, M. J. Mills, J. C. Sticht, L. A. Hankwitz, J. L. Wells, J. A. Jung, H. S. J Intensive Care Med 2022

Adult
Analgesics/therapeutic use
*Delirium/drug therapy
Humans
Hypnotics and Sedatives/therapeutic use
Intensive Care Units
Length of Stay
Pain/drug therapy
Respiration, Artificial
Retrospective Studies
analgesics
cost analysis
costs
critical care
hypnotics and sedatives
protocol

Improving Delirium Assessments in Vanderbilt Pediatric and Pediatric Cardiovascular Intensive Care Units Eken, H. N. Betters, K. A. Fuchs, D. C. Smith, H. A. B. Williams, S. R. Pediatr Qual Saf 2022
Outcomes in Post-operative Delirium Following Bowel Resection: A Single Center Retrospective Review Desrochers, R. M. Lynch, L. J. Gates, J. D. Ricaurte, D. Wade, J. T. Dicks, R. S. Keating, J. J. J Surg Res 2022

Bowel
Delirium
Elective
Emergency
Mortality
Resection

Efficacy and Safety of Remimazolam Besylate versus Dexmedetomidine for Sedation in Non-Intubated Older Patients with Agitated Delirium After Orthopedic Surgery: A Randomized Controlled Trial Deng, Y. Qin, Z. Wu, Q. Liu, L. Yang, X. Ju, X. Zhang, Y. Liu, L. Drug Des Devel Ther 2022

Benzodiazepines
*Delirium/drug therapy
*Dexmedetomidine/adverse effects
Humans
Hypnotics and Sedatives/adverse effects
*Orthopedic Procedures
agitation
delirium
dexmedetomidine
older adult
orthopedics
remimazolam besylate

Delirium, changes in cognitive function, and risk of diagnosed dementia after kidney transplantation Chu, N. M. Bae, S. Chen, X. Ruck, J. Gross, A. L. Albert, M. Neufeld, K. J. Segev, D. L. McAdams-DeMarco, M. A. Am J Transplant 2022

clinical research/practice
cognitive function
delirium
epidemiology
health services and outcomes research
kidney disease
kidney transplant
kidney transplantation/nephrology
mental health
neurology

Bispectral Index (BIS) Monitoring and Postoperative Delirium in Elderly Patients Undergoing Surgery: A Systematic Review and Meta-Analysis With Trial Sequential Analysis Chew, W. Z. Teoh, W. Y. Sivanesan, N. Loh, P. S. Shariffuddin,, II Ti, L. K. Ng, K. T. J Cardiothorac Vasc Anesth 2022

Bis
elderly
meta-analysis
postoperative cognitive dysfunction
postoperative delirium
systematic review

Delirium prevalence in geriatric emergency department patients: A systematic review and meta-analysis Chen, F. Liu, L. Wang, Y. Liu, Y. Fan, L. Chi, J. Am J Emerg Med 2022

Aged
*Delirium/diagnosis/epidemiology
Emergency Service, Hospital
Humans
Mass Screening
Prevalence
Delirium
Meta-analysis
Older adults

Improving quantification of anticholinergic burden using the Anticholinergic Effect on Cognition Scale - a healthcare improvement study in a geriatric ward setting Balasundaram, B. Ang, W. S. T. Stewart, R. Bishara, D. Ooi, C. H. Li, F. Akram, F. Eu Kwek, A. B. Australas Psychiatry 2022

Aged
*Cholinergic Antagonists/adverse effects
Cognition
*Cognition Disorders
Delivery of Health Care
Hospitals
Humans
anticholinergic burden scales
anticholinergic drugs
anticholinergic effect on cognition scale
delirium
dementia

The Association of Selective Serotonin Reuptake Inhibitors With Delirium in Critically Ill Adults: A Secondary Analysis of the Bringing to Light the Risk Factors and Incidence of Neuropsychologic Dysfunction in ICU Survivors ICU Study Austin, C. A. Yi, J. Lin, F. C. Pandharipande, P. Ely, E. W. Busby-Whitehead, J. Carson, S. S. Crit Care Explor 2022

delirium
intensive care unit outcomes
neurophysiology
neurotransmitters
selective serotonin reuptake inhibitors
interest.

Parental Education and Delirium Risk after Surgery in Older Adults Arias, F. Chen, F. Shiff, H. Marcantonio, E. R. Jones, R. N. Schmitt, E. M. Metzger, E. Fong, T. G. Travison, T. G. Inouye, S. K. Clin Gerontol 2022

Childhood socioeconomic status
delirium
social determinants of health

Informing the standardising of care for prolonged stay patients in the ICU: A scoping review of quality improvement tools Allum, L. Apps, C. Pattison, N. Connolly, B. Rose, L. Intensive Crit Care Nurs 2022

Bundle
Care standardisation
Checklist
Critical care
Persistent or chronic critical illness
Quality improvement

Monitoring of nighttime EEG slow-wave activity during dexmedetomidine infusion in patients with hyperactive ICU delirium: An observational pilot study Ala-Kokko, T. Erikson, K. Koskenkari, J. Laurila, J. Kortelainen, J. Acta Anaesthesiol Scand 2022

C-trend
Rcsq
sleep

Development of a Delirium Risk Predication Model among ICU Patients in Oman Al-Hoodar, R. K. Lazarus, E. R. Alomari, O. Alzaabi, O. Anesthesiol Res Pract 2022
Comparison Between Deltascan Single Channel Electroencephalography (EEG), Confusion Assessment Method-Intensive Care Unit (CAM-ICU) Score and Clinical Assessment in Diagnosing Delirium in Intubated Patients in the Intensive Care Unit Aben, J. Pouwels, S. Oldenbeuving, A. Cureus 2022

cam-icu
complications
delirium
electroencephalography
intensive care
monitoring

A Cross-Sectional Survey on the Clinical Management of Emergence Delirium in Adults: Knowledge, Attitudes, and Practice in Mainland China Yuan, Y. Lei, B. Li, Z. Wang, X. Zhao, H. Gao, M. Xue, Y. Zhang, W. Xiao, R. Meng, X. Zheng, H. Zhang, J. Wang, G. Guo, X. Brain Sci 2022

Pacu
anesthesia nurse
emergence delirium

Development and Validation of a Nomogram for Predicting Postoperative Delirium in Patients With Elderly Hip Fracture Based on Data Collected on Admission Yang, Y. Wang, T. Guo, H. Sun, Y. Cao, J. Xu, P. Cai, Y. Front Aging Neurosci 2022

albumin
chronic obstructive pulmonary disease
dementia
elderly hip fracture
nomogram
postoperative delirium
prediction model

Preoperative Inflammatory Markers and the Risk of Postoperative Delirium in Patients Undergoing Lumbar Spinal Fusion Surgery Yang, J. S. Lee, J. J. Kwon, Y. S. Kim, J. H. Sohn, J. H. J Clin Med 2022

CRP-to-albumin ratio
monocyte-to-lymphocyte ratio
neutrophil-to-lymphocyte ratio
postoperative delirium
spine surgery

An association between cancer type and delirium incidence in Japanese elderly patients: A retrospective longitudinal study Yamato, K. Ikeda, A. Endo, M. Filomeno, R. Kiyohara, K. Inada, K. Nishimura, K. Tanigawa, T. Cancer Med 2022

cancer
delirium
longitudinal study

Increased Direct Current-Electroencephalography Shifts During Induction of Anesthesia in Elderly Patients Developing Postoperative Delirium Windmann, V. Dreier, J. P. Major, S. Spies, C. Lachmann, G. Koch, S. Front Aging Neurosci 2022

*dc-eeg
*anesthesia induction
*blood–brain barrier
*direct current EEG
*electroencephalography
*hyperventilation
*postoperative delirium (POD)

Risk factors of delirium after gastrointestinal surgery: A meta-analysis Wang, X. Yu, D. Du, Y. Geng, J. J Clin Nurs 2022

delirium
gastrointestinal
risk factor

Physician Experience Design (PXD): More Usable Machine Learning Prediction for Clinical Decision Making Wang, L. Chignell, M. Zhang, Y. Pinto, A. Razak, F. Sheehan, K. Verma, A. AMIA Annu Symp Proc 2022

Artificial Intelligence
Clinical Decision-Making
Decision Making
*Delirium
Humans
Machine Learning
*Physicians/psychology

The Relationship Between Cardiovascular Disease Risk Score and Postoperative Delirium: The PNDABLE Study Wang, J. Wang, L. Tang, X. Wang, F. Liu, S. Wu, X. Dong, R. Lin, X. Wang, B. Bi, Y. Front Aging Neurosci 2022

biomarkers
cerebrospinal fluid
mediation analysis
postoperative delirium
vascular risk score
commercial or financial relationships that could be construed as a potential
conflict of interest.

Preoperative intervention to prevent delirium in patients with hip fracture - a systematic review Virsøe-Frandsen, C. D. Skjold, C. Wildgaard, K. Møller, A. M. Dan Med J 2022

Aged
*Delirium/etiology/prevention & control
Geriatric Assessment
*Hip Fractures/surgery
Humans
Odds Ratio
Preoperative Care

Coexisting delirium and excited catatonia Vellanki, K. D. Carroll, B. T. Ann Clin Psychiatry 2022

*Antipsychotic Agents/therapeutic use
*Catatonia
*Delirium/drug therapy
Humans

Confusion regarding the use of Natural Language Processing in ICU delirium assessment van Diem-Zaal, I. J. van den Boogaard, M. Kotfis, K. Ely, E. W. Intensive Care Med 2022

*Delirium/diagnosis
Humans
Intensive Care Units
*Natural Language Processing
Reproducibility of Results

Postoperative delirium and changes in the blood-brain barrier, neuroinflammation, and cerebrospinal fluid lactate: a prospective cohort study Taylor, J. Parker, M. Casey, C. P. Tanabe, S. Kunkel, D. Rivera, C. Zetterberg, H. Blennow, K. Pearce, R. A. Lennertz, R. C. Sanders, R. D. Br J Anaesth 2022

Biomarkers
*Blood-Brain Barrier
*Delirium/diagnosis
Humans
Interleukin-6
Lactic Acid
Neuroinflammatory Diseases
Prospective Studies
S100 Calcium Binding Protein beta Subunit/cerebrospinal fluid
*delirium
*dementia
*inflammation
*neuronal injury
*older adults
*surgery

Prospective clinical intervention study of aripiprazole and risperidone in the management of postoperative delirium in elderly patients after cardiovascular surgery Sugawara, H. Koyama, A. Maruyama, T. Koda, Y. Fukunaga, H. Ishikawa, T. Takebayashi, M. Okamoto, K. Fukui, T. Hashimoto, M. Psychiatry Clin Neurosci 2022
A simple risk score list can be used to predict the occurrence of delirium in patients admitted to inpatient hospice care: A medical record study Stoevelaar, R. Juffermans, C. C. M. Roorda, I. M. M. de Nijs, E. J. M. Hoornweg, J. Cannegieter, S. C. van der Linden, Y. M. Eur J Cancer Care (Engl) 2022

delirium
end-of-life care
hospice and palliative care nursing
hospice care
retrospective studies
terminal care

Chemokines in ICU Delirium: An Exploratory Study Smith, R. J. Rabinstein, A. A. Cartin-Ceba, R. Singh, V. P. Lachner, C. Khatua, B. Trivedi, S. Gajic, O. Crit Care Explor 2022

chemokine
cytokine
delirium
inflammation
intensive care unit
interest.

Cytokine profiles in intensive care unit delirium Smith, R. J. Lachner, C. Singh, V. P. Trivedi, S. Khatua, B. Cartin-Ceba, R. Acute Crit Care 2022

cytokine
delirium
encephalopathy
intensive care unit
neuroinflammation

Edmonton frailty scale score predicts postoperative delirium: a retrospective cohort analysis Sieber, F. Gearhart, S. Bettick, D. Wang, N. Y BMC Geriatr 2022

Cohort Studies
*Delirium/diagnosis/epidemiology/etiology
*Frailty/complications/diagnosis
Humans
Postoperative Complications/diagnosis/epidemiology/etiology
Prospective Studies
Retrospective Studies
Risk Factors
*Complications
*Delirium
*Elective surgical procedures
*Frailty
*Postoperative

Observation of Anesthetic Effect of Dexmedetomidine Combined With Intraspinal Anesthesia in Hip Arthroplasty and its Effect on Postoperative Delirium and Stress Response Shen, Y. Wang, C. Zhong, X. Wu, Y. He, X. Front Surg 2022

anesthetic effects
delirium
dexmedetomidine
hip replacement
immunologic function
intraspinal anesthesia
stress response
commercial or financial relationships that could be construed as a potential
conflict of interest.

Postoperative Application of Dexmedetomidine is the Optimal Strategy to Reduce the Incidence of Postoperative Delirium After Cardiac Surgery: A Network Meta-Analysis of Randomized Controlled Trials Shang, L. Hou, M. Guo, F. Ann Pharmacother 2022

cardiac surgery
cognitive dysfunction
dexmedetomidine
network meta-analysis
postoperative delirium

Decreasing delirium through music listening (DDM) in critically ill, mechanically ventilated older adults in the intensive care unit: a two-arm, parallel-group, randomized clinical trial Seyffert, S. Moiz, S. Coghlan, M. Balozian, P. Nasser, J. Rached, E. A. Jamil, Y. Naqvi, K. Rawlings, L. Perkins, A. J. Gao, S. Hunter, J. D., 3rd Khan, S. Heiderscheit, A. Chlan, L. L. Khan, B. Trials 2022

Aged
Critical Illness/psychology
*Delirium/diagnosis/prevention & control
Humans
Intensive Care Units
*Music
Pain
Respiration, Artificial/adverse effects
Acute respiratory failure
Anxiety
Cognition
Delirium
Intensive care unit
Mechanical ventilation
Music
Post-intensive care syndrome

Prevention of delirium with agitation by yokukansan in older adults after cancer surgery Sadahiro, R. Wada, S. Matsuoka, Y. J. Uchitomi, Y. Yamaguchi, T. Sato, T. Esaki, M. Yoshimoto, S. Daiko, H. Kanemitsu, Y. Kawai, A. Kato, T. Fujimoto, H. Uezono, Y. Shimizu, K. Matsuoka, H. Jpn J Clin Oncol 2022

clinical trial
gerontology
psycho-oncology
surgical oncology

Midazolam impacts acetyl-And butyrylcholinesterase genes: An epigenetic explanation for postoperative delirium? Rump, K. Holtkamp, C. Bergmann, L. Nowak, H. Unterberg, M. Orlowski, J. Thon, P. Bazzi, Z. Bazzi, M. Adamzik, M. Koos, B. Rahmel, T. PLoS One 2022

Acetylcholinesterase/metabolism
Butyrylcholinesterase
Cholinesterase Inhibitors/pharmacology
*Delirium/etiology
Epigenesis, Genetic
Histone Demethylases/metabolism
Histones/metabolism
Humans
Leukocytes, Mononuclear/metabolism
Lysine/metabolism
Midazolam/pharmacology
*Neuroblastoma/genetics

Ren, X. Zhang, S. Yang, Y. Song, A. Liang, F. Zhang, Y. Dong, Y. Wu, X. Xie, Z. Ketamine Induces Delirium-Like Behavior and Interferes With Endosomal Tau Trafficking Anesth Analg 2022
The crucial factors influencing the development and outcomes of postoperative delirium in proximal femur fractures Rajeev, A. Railton, C. Devalia, K. Aging Med (Milton) 2022

delirium
development
outcomes
postoperative
proximal femur fractures

Neuromonitoring depth of anesthesia and its association with postoperative delirium Pérez-Otal, B. Aragón-Benedí, C. Pascual-Bellosta, A. Ortega-Lucea, S. Martínez-Ubieto, J. Ramírez-Rodríguez, J. M. Sci Rep 2022

Anesthesia, General/adverse effects
*Anesthesiology
*Anesthetics
*Delirium/etiology/prevention & control
Humans
Postoperative Complications/epidemiology/etiology/prevention & control

Improving the Detection, Assessment, Management and Prevention of Delirium in Hospices (the DAMPen-D study): protocol for a co-design and feasibility study of a flexible and scalable implementation strategy to deliver guideline-adherent delirium care Pearson, M. Jackson, G. Jackson, C. Boland, J. Featherstone, I. Huang, C. Ogden, M. Sartain, K. Siddiqi, N. Twiddy, M. Johnson, M. BMJ Open 2022

*Delirium/diagnosis/prevention & control
Delivery of Health Care
Feasibility Studies
*Hospices
Humans
Wales
*delirium & cognitive disorders
*palliative care
*protocols & guidelines

An Interdisciplinary Reappraisal of Delirium and Proposed Subtypes Oldham, M. A. Slooter, A. J. C. Ely, E. W. Crone, C. Maldonado, J. R. Rosenthal, L. J. J Acad Consult Liaison Psychiatry 2022

acute encephalopathy
altered mental status
delirium disorder
neuropsychiatric symptoms
pathophysiology
subtypes

Postoperative Delirium in Patients with Oral Cancer: Is Intraoperative Fluid Administration a Neglected Risk Factor? Obermeier, K. T. Kraus, M. Smolka, W. Henkel, J. Saller, T. Otto, S. Liokatis, P. Cancers (Basel) 2022

fluid balance
fluid management
head and neck surgery
oral cancer
postoperative delirium

Risk of delirium associated with antimuscarinics in older adults: A case-time-control study Nishtala, P. S. Chyou, T. Y. Pharmacoepidemiol Drug Saf 2022

Aged
Aged, 80 and over
Cholinergic Antagonists
*Delirium/chemically induced/drug therapy/epidemiology
Humans
Muscarinic Antagonists/adverse effects
Solifenacin Succinate/adverse effects
*Urinary Bladder, Overactive/chemically induced
*adverse effects
*antimuscarinics
*delirium
*elderly
*pharmacoepidemiology

Potential effects of regular use of antihypertensive drugs for in-hospital delirium in geriatric patients with trauma Nagasawa, H. Omori, K. Ota, S. Muramatsu, K. I. Ishikawa, K. Yanagawa, Y. Sci Rep 2022

Aged
*Antihypertensive Agents/therapeutic use
*Delirium/drug therapy/epidemiology/etiology
Hospital Mortality
Hospitals
Humans
Retrospective Studies

Performance of Melatonin as Prophylaxis in Geriatric Patients with Multifactorial Risk for Postoperative Delirium Development: A Randomized Comparative Study Mohamed, S. A. Rady, A. Youssry, M. Abdelaziz Mohamed, M. R. Gamal, M. Turk J Anaesthesiol Reanim 2022
Perioperative risk factors associated with increased incidence of postoperative delirium: systematic review, meta-analysis, and Grading of Recommendations Assessment, Development, and Evaluation system report of clinical literature Mevorach, L. Forookhi, A. Farcomeni, A. Romagnoli, S. Bilotta, F. Br J Anaesth 2022

Grade
delirium
intensive care unit
meta-analysis
perioperative
postoperative
review
risk factors

Delirium in ICU Patients after Cardiac Arrest: A Scoping Review Mędrzycka-Dąbrowska, W. Lange, S. Religa, D. Dąbrowski, S. Friganović, A. Oomen, B. Krupa, S. J Pers Med 2022

Icu
a scoping review
cardiac arrest
delirium
resuscitation

Epidemiology of delirium in hospitalized patients in Latin America: A systematic review Maximiliano, B. Sebastian, B. Estefania, A. Irma, C. Gutierrez, P. Daniela, P. Pv Roberta, C. Eduardo, T. Jose, M. Felipe, S. Acta Psychiatr Scand 2022

Latin America
acute confusional syndrome
delirium
incidence
prevalence

Effect of Perioperative Dexmedetomidine Infusion on Postoperative Delirium in Elderly Patients Undergoing Oral and Maxillofacial Surgery: A Randomized Controlled Clinical Trial Liu, T. Tuo, J. Wei, Q. Sun, X. Zhao, H. Zhao, X. Qu, M. Int J Gen Med 2022

dexmedetomidine
elderly
oral and maxillofacial surgery
postoperative delirium

Type 2 Diabetes Mellitus with Tight Glucose Control and Poor Pre-Injury Stair Climbing Capacity May Predict Postoperative Delirium: A Secondary Analysis Liu, K. Song, Y. Yuan, Y. Li, Z. Wang, X. Zhang, W. Li, Y. Mi, X. Han, D. Rong, Y. Guo, X. Wang, G. Brain Sci 2022

glycemic control
hip fracture
physical performance
postoperative delirium
type 2 diabetes mellitus

Preoperative Plasma Tau-PT217 and Tau-PT181 Are Associated With Postoperative Delirium Liang, F. Baldyga, K. Quan, Q. Khatri, A. Choi, S. Wiener-Kronish, J. Akeju, O. Westover, B. M. Cody, K. Shen, Y. Marcantonio, E. R. Xie, Z. Ann Surg 2022
Development and Validation of Simplified Delirium Prediction Model in Intensive Care Unit Kim, M. K. Oh, J. Kim, J. J. Park, J. Y. Front Psychiatry 2022

critical care
delirium
intensive care unit
prediction model
simplified model
commercial or financial relationships that could be construed as a potential
conflict of interest.

The effects of hypomagnesemia on delirium in middle-aged and older adult patients admitted to medical intensive care units Kim, J. Y. Lee, H. J. Lee, H. Y. Lee, S. M. Lee, J. Park, T. Y. Acute Crit Care 2022

delirium
hypomagnesemia
intensive care unit

Structural integrity of the anterior mid-cingulate cortex contributes to resilience to delirium in SuperAging Katsumi, Y. Wong, B. Cavallari, M. Fong, T. G. Alsop, D. C. Andreano, J. M. Carvalho, N. Brickhouse, M. Jones, R. Libermann, T. A. Marcantonio, E. R. Schmitt, E. Shafi, M. M. Pascual-Leone, A. Travison, T. Barrett, L. F. Inouye, S. K. Dickerson, B. C. Tou Brain Commun 2022

Mri
cortical thickness
postoperative delirium
salience network
successful aging

"Excited delirium," erroneous concepts, dehumanizing language, false narratives, and threat to Black lives Fiscella, K. Pinals, D. A. Shields, C. G. Acad Emerg Med 2022

*Delirium/diagnosis
Humans
*Language

Knowing the Older Adult With Delirium Superimposed on Dementia Fick, D. M. Am J Geriatr Psychiatry 2022

Delirium
aging
dementia
detection

Bibliometric Analysis of 100 Most-Cited Articles in Delirium Fei, X. Zeng, Q. Wang, J. Gao, Y. Xu, F. Front Psychiatry 2022

bibliometric analysis
bibliometrics
cognitive disorder
delirium
psychiatry
top-100
commercial or financial relationships that could be construed as a potential
conflict of interest.

Transcutaneous Electrical Acupoint Stimulation Combined With Auricular Acupressure Reduces Postoperative Delirium Among Elderly Patients Following Major Abdominal Surgery: A Randomized Clinical Trial Fan, Q. Lei, C. Wang, Y. Yu, N. Wang, L. Fu, J. Dong, H. Lu, Z. Xiong, L. Front Med (Lausanne) 2022

abdominal surgery
auricular acupressure
delirium
elderly
transcutaneous electric acupoint stimulation
commercial or financial relationships that could be construed as a potential
conflict of interest.

Depression is associated with delirium after cardiac surgery-a population-based cohort study Falk, A. Kåhlin, J. Nymark, C. Hultgren, R. Stenman, M. Interact Cardiovasc Thorac Surg 2022

Aged
*Cardiac Surgical Procedures/adverse effects
Cohort Studies
*Delirium/diagnosis/epidemiology/etiology
Depression/diagnosis/epidemiology
Humans
Postoperative Complications/etiology
Prospective Studies
Risk Factors
Cardiac surgery
Depression
Patient Health Questionnaire-9
Postoperative delirium
Screening

Association of delirium screening on hospitalized adults and postacute care utilization: A retrospective cohort study Dulin, J. D. Zhang, J. Marsden, J. Mauldin, P. D. Moran, W. P. Kalivas, B. C. Am J Med Sci 2022
Adaptation, implementation, and mixed methods evaluation of an interprofessional modular clinical practice guideline for delirium management on an inpatient palliative care unit Bush, S. H. Skinner, E. Lawlor, P. G. Dhuper, M. Grassau, P. A. Pereira, J. L. MacDonald, A. R. Parsons, H. A. Kabir, M. BMC Palliat Care 2022

Adult
*Delirium/therapy
Focus Groups
*Hospice and Palliative Care Nursing
Humans
Inpatients
Palliative Care
Clinical practice guideline
Delirium
Educational activities
Implementation
Interprofessional
Knowledge translation
Learning
Mixed methods
Quality improvement

Older age, delirium, dementia, frailty, and critical care: Care priorities Bloomer, M. J. Woszczeiko, C. Hutchinson, A. M. Intensive Crit Care Nurs 2002

Critical care
Delirium
Dementia
Frail elderly
Intensive care

Early Diagnosis of Delirium in Palliative Care Patients Decreases Mortality and Necessity of Palliative Sedation: Results of a Prospective Observational Study Beretta, M. Uggeri, S. Santucci, C. Cattaneo, M. Ermolli, D. Gerosa, C. Ornaghi, M. Roccasalva, A. Santambrogio, P. Varrassi, G. Corli, O. Cureus 2022

clinical outcome
delirium
early diagnosis
end of life
mortality
palliative care

Incidence and associations of hospital delirium diagnoses in 85,979 people with severe mental illness: A data linkage study Bauernfreund, Y. Launders, N. Favarato, G. Hayes, J. F. Osborn, D. Sampson, E. L. Acta Psychiatr Scand 2022

bipolar disorder
databases
delirium
psychotic disorders
schizophrenia

The Pharmacogenetics of Opiates and Its Impact on Delirium in Mechanically Ventilated Adults: A Pilot Study Austin, C. A. Szeto, A. Gupta, A. Wiltshire, T. Crona, D. J. Kistler, C. J Pharm Technol 2022

analgesics
delirium
genetics
intensive care unit
opioids
pharmacogenetics
conflicts of interest with respect to the research, authorship, and/or
publication of this article.

Agents intervening against delirium in the intensive care unit trial-Protocol for a secondary Bayesian analysis Andersen-Ranberg, N. Poulsen, L. M. Perner, A. Hästbacka, J. Morgan, M. P. G. Citerio, G. Oxenbøll-Collet, M. Weber, S. O. Andreasen, A. S. Bestle, M. H. Uslu, B. Pedersen, H. B. S. Nielsen, L. G. Damgaard, K. Jensen, T. B. Sommer, T. Dey, N. Mathiesen, Acta Anaesthesiol Scand 2022

Adult
*Antipsychotic Agents/therapeutic use
Bayes Theorem
*Delirium/drug therapy
Haloperidol/therapeutic use
Humans
Intensive Care Units
Bayesian statistics
Delirium
Icu
haloperidol

Increased Direct Current-Electroencephalography Shifts During Induction of Anesthesia in Elderly Patients Developing Postoperative Delirium Windmann, V. Dreier, J. P. Major, S. Spies, C. Lachmann, G. Koch, S. Front Aging Neurosci 2022

*dc-eeg
*anesthesia induction
*blood–brain barrier
*direct current EEG
*electroencephalography
*hyperventilation
*postoperative delirium (POD)

The Effect of Propofol versus Sevoflurane on Postoperative Delirium in Parkinson's Disease Patients Undergoing Deep Brain Stimulation Surgery: An Observational Study Zhou, Y. Li, Z. Ma, Y. Yu, C. Chen, Y. Ding, J. Yu, J. Zhou, R. Wang, X. Liu, T. Guo, X. Fan, T. Shi, C. Brain Sci 2022

Parkinson’s disease
anesthesia maintenance
postoperative delirium
propofol
sevoflurane