What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Neuroleptic strategies for terminal agitation in patients with cancer and delirium at an acute palliative care unit: a single-centre, double-blind, parallel-group, randomised trial
- Authors
- Hui, D. De La Rosa, A. Wilson, A. Nguyen, T. Wu, J. Delgado-Guay, M. Azhar, A. Arthur, J. Epner, D. Haider, A. De La Cruz, M. Heung, Y. Tanco, K. Dalal, S. Reddy, A. Williams, J. Amin, S. Armstrong, T. S. Breitbart, W. Bruera, E.
- Year
- 2020
- Journal
- Lancet Oncol
- Abstract
BACKGROUND: The role of neuroleptics for terminal agitated delirium is controversial. We assessed the effect of three neuroleptic strategies on refractory agitation in patients with cancer with terminal delirium. METHODS: In this single-centre, double-blind, parallel-group, randomised trial, patients with advanced cancer, aged at least 18 years, admitted to the palliative and supportive care unit at the University of Texas MD Anderson Cancer Center (Houston, TX, USA), with refractory agitation, despite low-dose haloperidol, were randomly assigned to receive intravenous haloperidol dose escalation at 2 mg every 4 h, neuroleptic rotation with chlorpromazine at 25 mg every 4 h, or combined haloperidol at 1 mg and chlorpromazine at 12·5 mg every 4 h, until death or discharge. Rescue doses identical to the scheduled doses were administered at inception, and then hourly as needed. Permuted block randomisation (block size six; 1:1:1) was done, stratified by baseline Richmond Agitation Sedation Scale (RASS) scores. Research staff, clinicians, patients, and caregivers were masked to group assignment. The primary outcome was change in RASS score from time 0 to 24 h. Comparisons among group were done by modified intention-to-treat analysis. This completed study is registered with ClinicalTrials.gov, NCT03021486. FINDINGS: Between July 5, 2017, and July 1, 2019, 998 patients were screened for eligibility, with 68 being enrolled and randomly assigned to treatment; 45 received the masked study interventions (escalation n=15, rotation n=16, combination n=14). RASS score decreased significantly within 30 min and remained low at 24 h in the escalation group (n=10, mean RASS score change between 0 h and 24 h -3·6 [95% CI -5·0 to -2·2]), rotation group (n=11, -3·3 [-4·4 to -2·2]), and combination group (n=10, -3·0 [-4·6 to -1·4]), with no difference among groups (p=0·71). The most common serious toxicity was hypotension (escalation n=6 [40%], rotation n=5 [31%], combination n=3 [21%]); there were no treatment-related deaths. INTERPRETATION: Our data provide preliminary evidence that the three strategies of neuroleptics might reduce agitation in patients with terminal agitation. These findings are in the context of the single-centre design, small sample size, and lack of a placebo-only group. FUNDING: National Institute of Nursing Research.
- PMID
- Keywords
Aged
Antipsychotic Agents/ therapeutic use
Delirium/ drug therapy/etiology/pathology
Double-Blind Method
Female
Follow-Up Studies
Haloperidol/ therapeutic use
Humans
Male
Middle Aged
Neoplasms/ complications/psychology/therapy
Palliative Care
Prognosis
Psychomotor Agitation/ drug therapy/etiology/pathology
- Page(s)
- 989-998
- Volume
- 21
- Issue
- 7
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| Potential effects of regular use of antihypertensive drugs for in-hospital delirium in geriatric patients with trauma | Nagasawa, H. Omori, K. Ota, S. Muramatsu, K. I. Ishikawa, K. Yanagawa, Y. | Sci Rep | 2022 |
Aged |
| Performance of Melatonin as Prophylaxis in Geriatric Patients with Multifactorial Risk for Postoperative Delirium Development: A Randomized Comparative Study | Mohamed, S. A. Rady, A. Youssry, M. Abdelaziz Mohamed, M. R. Gamal, M. | Turk J Anaesthesiol Reanim | 2022 | |
| Perioperative risk factors associated with increased incidence of postoperative delirium: systematic review, meta-analysis, and Grading of Recommendations Assessment, Development, and Evaluation system report of clinical literature | Mevorach, L. Forookhi, A. Farcomeni, A. Romagnoli, S. Bilotta, F. | Br J Anaesth | 2022 |
Grade |
| Delirium in ICU Patients after Cardiac Arrest: A Scoping Review | Mędrzycka-Dąbrowska, W. Lange, S. Religa, D. Dąbrowski, S. Friganović, A. Oomen, B. Krupa, S. | J Pers Med | 2022 |
Icu |
| Epidemiology of delirium in hospitalized patients in Latin America: A systematic review | Maximiliano, B. Sebastian, B. Estefania, A. Irma, C. Gutierrez, P. Daniela, P. Pv Roberta, C. Eduardo, T. Jose, M. Felipe, S. | Acta Psychiatr Scand | 2022 |
Latin America |
| Effect of Perioperative Dexmedetomidine Infusion on Postoperative Delirium in Elderly Patients Undergoing Oral and Maxillofacial Surgery: A Randomized Controlled Clinical Trial | Liu, T. Tuo, J. Wei, Q. Sun, X. Zhao, H. Zhao, X. Qu, M. | Int J Gen Med | 2022 |
dexmedetomidine |
| Type 2 Diabetes Mellitus with Tight Glucose Control and Poor Pre-Injury Stair Climbing Capacity May Predict Postoperative Delirium: A Secondary Analysis | Liu, K. Song, Y. Yuan, Y. Li, Z. Wang, X. Zhang, W. Li, Y. Mi, X. Han, D. Rong, Y. Guo, X. Wang, G. | Brain Sci | 2022 |
glycemic control |
| Preoperative Plasma Tau-PT217 and Tau-PT181 Are Associated With Postoperative Delirium | Liang, F. Baldyga, K. Quan, Q. Khatri, A. Choi, S. Wiener-Kronish, J. Akeju, O. Westover, B. M. Cody, K. Shen, Y. Marcantonio, E. R. Xie, Z. | Ann Surg | 2022 | |
| Development and Validation of Simplified Delirium Prediction Model in Intensive Care Unit | Kim, M. K. Oh, J. Kim, J. J. Park, J. Y. | Front Psychiatry | 2022 |
critical care |
| The effects of hypomagnesemia on delirium in middle-aged and older adult patients admitted to medical intensive care units | Kim, J. Y. Lee, H. J. Lee, H. Y. Lee, S. M. Lee, J. Park, T. Y. | Acute Crit Care | 2022 |
delirium |
| Structural integrity of the anterior mid-cingulate cortex contributes to resilience to delirium in SuperAging | Katsumi, Y. Wong, B. Cavallari, M. Fong, T. G. Alsop, D. C. Andreano, J. M. Carvalho, N. Brickhouse, M. Jones, R. Libermann, T. A. Marcantonio, E. R. Schmitt, E. Shafi, M. M. Pascual-Leone, A. Travison, T. Barrett, L. F. Inouye, S. K. Dickerson, B. C. Tou | Brain Commun | 2022 |
Mri |
| "Excited delirium," erroneous concepts, dehumanizing language, false narratives, and threat to Black lives | Fiscella, K. Pinals, D. A. Shields, C. G. | Acad Emerg Med | 2022 |
*Delirium/diagnosis |
| Knowing the Older Adult With Delirium Superimposed on Dementia | Fick, D. M. | Am J Geriatr Psychiatry | 2022 |
Delirium |
| Bibliometric Analysis of 100 Most-Cited Articles in Delirium | Fei, X. Zeng, Q. Wang, J. Gao, Y. Xu, F. | Front Psychiatry | 2022 |
bibliometric analysis |
| Transcutaneous Electrical Acupoint Stimulation Combined With Auricular Acupressure Reduces Postoperative Delirium Among Elderly Patients Following Major Abdominal Surgery: A Randomized Clinical Trial | Fan, Q. Lei, C. Wang, Y. Yu, N. Wang, L. Fu, J. Dong, H. Lu, Z. Xiong, L. | Front Med (Lausanne) | 2022 |
abdominal surgery |
| Depression is associated with delirium after cardiac surgery-a population-based cohort study | Falk, A. Kåhlin, J. Nymark, C. Hultgren, R. Stenman, M. | Interact Cardiovasc Thorac Surg | 2022 |
Aged |
| Association of delirium screening on hospitalized adults and postacute care utilization: A retrospective cohort study | Dulin, J. D. Zhang, J. Marsden, J. Mauldin, P. D. Moran, W. P. Kalivas, B. C. | Am J Med Sci | 2022 | |
| Adaptation, implementation, and mixed methods evaluation of an interprofessional modular clinical practice guideline for delirium management on an inpatient palliative care unit | Bush, S. H. Skinner, E. Lawlor, P. G. Dhuper, M. Grassau, P. A. Pereira, J. L. MacDonald, A. R. Parsons, H. A. Kabir, M. | BMC Palliat Care | 2022 |
Adult |
| Older age, delirium, dementia, frailty, and critical care: Care priorities | Bloomer, M. J. Woszczeiko, C. Hutchinson, A. M. | Intensive Crit Care Nurs | 2002 |
Critical care |
| Early Diagnosis of Delirium in Palliative Care Patients Decreases Mortality and Necessity of Palliative Sedation: Results of a Prospective Observational Study | Beretta, M. Uggeri, S. Santucci, C. Cattaneo, M. Ermolli, D. Gerosa, C. Ornaghi, M. Roccasalva, A. Santambrogio, P. Varrassi, G. Corli, O. | Cureus | 2022 |
clinical outcome |
| Incidence and associations of hospital delirium diagnoses in 85,979 people with severe mental illness: A data linkage study | Bauernfreund, Y. Launders, N. Favarato, G. Hayes, J. F. Osborn, D. Sampson, E. L. | Acta Psychiatr Scand | 2022 |
bipolar disorder |
| The Pharmacogenetics of Opiates and Its Impact on Delirium in Mechanically Ventilated Adults: A Pilot Study | Austin, C. A. Szeto, A. Gupta, A. Wiltshire, T. Crona, D. J. Kistler, C. | J Pharm Technol | 2022 |
analgesics |
| Agents intervening against delirium in the intensive care unit trial-Protocol for a secondary Bayesian analysis | Andersen-Ranberg, N. Poulsen, L. M. Perner, A. Hästbacka, J. Morgan, M. P. G. Citerio, G. Oxenbøll-Collet, M. Weber, S. O. Andreasen, A. S. Bestle, M. H. Uslu, B. Pedersen, H. B. S. Nielsen, L. G. Damgaard, K. Jensen, T. B. Sommer, T. Dey, N. Mathiesen, | Acta Anaesthesiol Scand | 2022 |
Adult |
| Increased Direct Current-Electroencephalography Shifts During Induction of Anesthesia in Elderly Patients Developing Postoperative Delirium | Windmann, V. Dreier, J. P. Major, S. Spies, C. Lachmann, G. Koch, S. | Front Aging Neurosci | 2022 |
*dc-eeg |
| The Effect of Propofol versus Sevoflurane on Postoperative Delirium in Parkinson's Disease Patients Undergoing Deep Brain Stimulation Surgery: An Observational Study | Zhou, Y. Li, Z. Ma, Y. Yu, C. Chen, Y. Ding, J. Yu, J. Zhou, R. Wang, X. Liu, T. Guo, X. Fan, T. Shi, C. | Brain Sci | 2022 |
Parkinson’s disease |
| Association between smoking and postoperative delirium in surgical patients with pulmonary hypertension: a secondary analysis of a cohort study | Zhou, S. Shi, S. Xie, C. Chen, G. | BMC Psychiatry | 2022 |
Cohort Studies |
| Comorbidity patterns in institutionalized older adults affected by dementia | Zazzara, M. B. Vetrano, D. L. Carfì, A. Liperoti, R. Damiano, C. Onder, G. | Alzheimers Dement (Amst) | 2022 |
care pathways |
| The Impact of Perioperative and Predisposing Risk Factors on the Development of Postoperative Delirium and a Possible Gender Difference | Wittmann, M. Kirfel, A. Jossen, D. Mayr, A. Menzenbach, J. | Geriatrics (Basel) | 2022 |
gender difference |
| Four-in-One: A Comprehensive Checklist for the Assessment of Pain, Undersedation, Iatrogenic Withdrawal and Delirium in the PICU: A Delphi Study | van Dijk, M. Ista, E. | Front Pediatr | 2022 |
Iws |
| Analgesia, Sedation, Paralytics, Delirium, and Iatrogenic Withdrawal | Valentine, K. Kummick, J. | Pediatr Clin North Am | 2022 |
*Analgesia |
| Antipsychotic prescribing in people admitted to hospital with dementia or delirium | Tumusiime, W. A. Hardman, C. J. Breen, J. L. | Australas J Ageing | 2022 |
*Antipsychotic Agents/therapeutic use |
| Breaking barriers in postoperative delirium | Terrando, N. Akassoglou, K. | Br J Anaesth | 2022 |
biomarker |
| The Relationship Between Suboptimal Social Networks and Postoperative Delirium: The PNDABLE Study | Tang, X. Yv, H. Wang, F. Wang, J. Liu, S. Wu, X. Dong, R. Lin, X. Wang, B. Bi, Y. | Front Aging Neurosci | 2022 |
cerebrospinal fluid |
| Delirium incidence and risk factors in patients undergoing non-invasive ventilation for acute respiratory failure: a multicenter observational trial | Tabbì, L. Tonelli, R. Comellini, V. Dongilli, R. Sorgentone, S. Spacone, A. Paonessa, M. C. Sacchi, M. Falsini, L. Boni, E. Ribuffo, V. Bruzzi, G. Castaniere, I. Fantini, R. Marchioni, A. Pisani, L. Nava, S. Clini, E. | Minerva Anestesiol | 2022 | |
| The association between Monocyte-to-Lymphocyte ratio and postoperative delirium in ICU patients in cardiac surgery | Su, X. Wang, J. Lu, X. | J Clin Lab Anal | 2022 |
inflammatory markers |
| Development of a non-pharmacologic delirium management bundle in paediatric intensive care units | Stenkjaer, R. L. Herling, S. F. Egerod, I. Weis, J. van Dijk, M. Kudchadkar, S. R. Ramelet, A. S. Ista, E. | Nurs Crit Care | 2022 |
delirium |
| Delirium in hospitalised adults with acute burns - A systematic review | Stanley, G. H. M. Barber, A. R. J. O'Brien, A. M. Hamill, C. Boardman, G. Frear, C. C. Edgar, D. W. Seymour, H. Wood, F. M. | Burns | 2022 |
Burns |
| Delirium associated with buprenorphine use in cardiac surgery: A retrospective cohort study | Selvaraj, T. Thangavel, P. Siddhaarth, K. | Indian J Anaesth | 2022 |
Aged |
| Influence of perioperative dexmedetomidine on the incidence of postoperative delirium in adult patients undergoing cardiac surgery | Patel, M. Onwochei, D. N. Desai, N. | Br J Anaesth | 2022 |
Adult |
| Association Between Implementation of a Geriatric Trauma Clinical Pathway and Changes in Rates of Delirium in Older Adults With Traumatic Injury | Park, C. Bharija, A. Mesias, M. Mitchell, A. Krishna, P. Storr-Street, N. Brown, A. Martin, M. Lu, A. C. Staudenmayer, K. L. | JAMA Surg | 2022 | |
| Intraoperative hyperoxygenation may negatively affect postoperative cognitive functions in coronary artery bypass graft operations: A randomized controlled study | Onur, T. Karaca, Ü Ata, F. Sayan, H. E. Onur, A. Yilmaz, C. Balkaya, A. N. Eriş, C. | J Card Surg | 2022 |
cardiopulmonary bypass |
| Investigation of Risk Factors for Postoperative Delirium after Transcatheter Aortic Valve Implantation: A Retrospective Study | Ogata, Y. Kobayashi, N. Yamauchi, M. | J Clin Med | 2022 |
aortic stenosis |
| Mobilization in the evening to prevent delirium: A pilot randomized trial | Nydahl, P. McWilliams, D. Weiler, N. Borzikowsky, C. Howroyd, F. Brobeil, A. Lindner, M. von Haken, R. | Nurs Crit Care | 2022 |
Critical Care |
| Delirium on stroke units: a prospective, multicentric quality-improvement project | Nydahl, P. Baumgarte, F. Berg, D. Bergjan, M. Borzikowsky, C. Franke, C. Green, D. Hannig, A. Hansen, H. C. Hauss, A. Hansen, U. Istel, R. Krämer, N. Krause, K. Lohrmann, R. Mohammadzadeh-Vazifeh, M. Osterbrink, J. Palm, F. Petersen, T. Schöller, B. Sto | J Neurol | 2022 |
*Delirium/diagnosis/epidemiology/etiology |
| The relationship of acute delirium with cognitive and psychiatric symptoms after stroke: a longitudinal study | Nerdal, V. Gjestad, E. Saltvedt, I. Munthe-Kaas, R. Ihle-Hansen, H. Ryum, T. Lydersen, S. Grambaite, R. | BMC Neurol | 2022 |
Aged |
| Alpha-2-adrenergic receptor agonists for the prevention of delirium and cognitive decline after open heart surgery (ALPHA2PREVENT): protocol for a multicentre randomised controlled trial | Neerland, B. E. Busund, R. Haaverstad, R. Helbostad, J. L. Landsverk, S. A. Martinaityte, I. Norum, H. M. Ræder, J. Selbaek, G. Simpson, M. R. Skaar, E. Skjærvold, N. K. Skovlund, E. Slooter, A. J. Svendsen Ø, S. Tønnessen, T. Wahba, A. Zetterberg, H. | BMJ Open | 2022 |
Adrenergic alpha-2 Receptor Agonists/therapeutic use |
| Does modulation of glymphatic system reduce delirium via waste clearance? | Naaz, S. Asghar, A. | J Anaesthesiol Clin Pharmacol | 2022 | |
| Delirium in elderly postoperative patients: A prospective cohort study | Muzzana, C. Mantovan, F. Huber, M. K. Trevisani, K. Niederbacher, S. Kugler, A. Ausserhofer, D. | Nurs Open | 2022 |
delirium |
| Antimicrobial neurotoxicity: an under-recognised cause of delirium | Moynan, D. Maqbool, E. de Barra, E. | Acute Med | 2022 |
Aged |
| CORR Insights®: Does the SORG Orthopaedic Research Group Hip Fracture Delirium Algorithm Perform Well on an Independent Intercontinental Cohort of Patients With Hip Fractures Who Are 60 Years or Older? | Michelson, J. D. | Clin Orthop Relat Res | 2022 | |
| Drug Choice for Hyperactive Delirium in Terminally-Ill Cancer Patients: A Nationwide Survey | Matsuda, Y. Morita, T. Oya, K. Tagami, K. Naito, A. S. Kashiwagi, H. Otani, H. | J Pain Symptom Manage | 2022 |
cancer |
| Implementing delirium screening in the emergency department: a quality improvement project | Martin, L. Lyons, M. Patton, A. O. Driscoll M McLoughlin, K. Hannon, E. Deasy, C. | BMJ Open Qual | 2022 |
Aged |
| Evaluation of the association of anticholinergic burden and delirium in older hospitalised patients - A cohort study comparing 19 anticholinergic burden scales | Lisibach, A. Gallucci, G. Benelli, V. Kälin, R. Schulthess, S. Beeler, P. E. Csajka, C. Lutters, M. | Br J Clin Pharmacol | 2022 |
Doss |
| Demand Ischemia as a Predictor of Mortality in Older Patients With Delirium | Kumar, M. Patil, S. Godoy, L. D. C. Kuo, C. L. Swede, H. Kuchel, G. A. Chen, K. | Front Cardiovasc Med | 2022 |
clinical outcomes |
| Structured Delirium Management in the Hospital | Krämer, J. Nolte, K. Zupanc, L. Schnitker, S. Roos, A. Göpel, C. Cid, J. S. Eichler, K. Hooven, T. V. D. Hempel, G. Pavenstädt, H. J. Klaas, C. Gosheger, G. Raschke, M. J. Wiendl, H. Duning, T. | Dtsch Arztebl Int | 2022 |
Activities of Daily Living |
| A machine learning approach to identifying delirium from electronic health records | Kim, J. H. Hua, M. Whittington, R. A. Lee, J. Liu, C. Ta, C. N. Marcantonio, E. R. Goldberg, T. E. Weng, C. | JAMIA Open | 2022 |
Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) |
| Effects of nonpharmacological interventions on sleep improvement and delirium prevention in critically ill patients: A systematic review and meta-analysis | Kang, J. Cho, Y. S. Lee, M. Yun, S. Jeong, Y. J. Won, Y. H. Hong, J. Kim, S. | Aust Crit Care | 2022 |
Critical care |
| A machine-learning model to predict postoperative delirium following knee arthroplasty using electronic health records | Jung, J. W. Hwang, S. Ko, S. Jo, C. Park, H. Y. Han, H. S. Lee, M. C. Park, J. E. Ro, D. H. | BMC Psychiatry | 2022 |
*Arthroplasty, Replacement, Knee/adverse effects |
| Tranexamic Acid and the Risk of Delirium after Off-Pump Surgery | Hulde, N. Zittermann, A. Deutsch, M. A. Gummert, J. F. von Dossow, V. Koster, A. | Thorac Cardiovasc Surg | 2022 | |
| Early Serum Metabolism Profile of Post-operative Delirium in Elderly Patients Following Cardiac Surgery With Cardiopulmonary Bypass | Huang, H. Han, J. Li, Y. Yang, Y. Shen, J. Fu, Q. Chen, Y. | Front Aging Neurosci | 2022 |
cardiopulmonary bypass |
| Delirium Item Bank: Utilization to Evaluate and Create Delirium Instruments | Helfand, B. K. I. Tommet, D. Detroyer, E. Milisen, K. Adamis, D. Metzger, E. D. Marcantonio, E. R. Boudreaux, E. D. Inouye, S. K. Jones, R. N. | Dement Geriatr Cogn Disord | 2022 |
Aged |
| Low Dose Antipsychotics for the Treatment of Delirium in Hospitalized Elderly Patients and Their Effects on QTc Interval | Heidari, S. Kargar, M. | J Pharm Pract | 2022 |
adverse drug events |
| Melatonin and Its Analogs for Prevention of Post-cardiac Surgery Delirium: A Systematic Review and Meta-Analysis | Han, Y. Tian, Y. Wu, J. Zhu, X. Wang, W. Zeng, Z. Qin, Z. | Front Cardiovasc Med | 2022 |
cardiac |
| The Role of Acetylcholinesterase Inhibitors in the Treatment of Prolonged Postelectroconvulsive Therapy Delirium | Gutowski, B. Bomasang-Layno, E. | Case Rep Psychiatry | 2022 | |
| Risk factors for delirium in elderly patients after lumbar spinal fusion | Gold, C. Ray, E. Christianson, D. Park, B. Kournoutas, I. A. Kahn, T. A. Perez, E. A. Berger, J. I. Sander, K. Igram, C. A. Pugely, A. Olinger, C. R. Carnahan, R. Chen, P. F. Mueller, R. Hitchon, P. Howard, M. A. Banks, M. Sanders, R. D. Woodroffe, R. W. | Clin Neurol Neurosurg | 2022 |
Geriatric spine surgery |
| Instruments to Identify Delirium in Patients Recovering From Anesthesia: A Scoping Review | Gnatta, J. R. Cavassana, T. M. Nascimento, A. S. D. Poveda, V. B. | J Perianesth Nurs | 2022 |
delirium |
| Identifying Patients With Delirium Based on Unstructured Clinical Notes: Observational Study | Ge, W. Alabsi, H. Jain, A. Ye, E. Sun, H. Fernandes, M. Magdamo, C. Tesh, R. A. Collens, S. I. Newhouse, A. Mvr Moura, L. Zafar, S. Hsu, J. Akeju, O. Robbins, G. K. Mukerji, S. S. Das, S. Westover, M. B. | JMIR Form Res | 2022 |
clinical notes |
| Predictors of post-stroke delirium incidence and duration: results of a prospective observational study using high frequency delirium screening | Fleischmann, R. Andrasch, T. Warwas, S. Kunz, R. Gross, S. Witt, C. Ruhnau, J. Vogelgesang, A. Ulm, L. Mengel, A. von Sarnowski, B. | Int J Stroke | 2022 |
Acute stroke therapy |
| Italian Version of the Cornell Assessment of Pediatric Delirium: Evaluation of the Scale Reliability and Ability to Detect Delirium Compared to Pediatric Intensive Care Unit Physicians Clinical Evaluation | Fazio, P. C. Daverio, M. Masola, M. D'Angelo, I. Frison, S. Zaggia, C. Simeone, S. Pucciarelli, G. Gregori, D. Comoretto, R. Amigoni, A. | Front Pediatr | 2022 |
Capd |
| Regional anesthesia techniques and postoperative delirium: systematic review and meta-analysis | Fanelli, A. Balzani, E. Memtsoudis, S. Abdallah, F. W. Mariano, E. R. | Minerva Anestesiol | 2023 |
Aged |
| Delirium with delayed diagnosis of hereditary coproporphyria | Eroglu, S. Birsenogul, I. | Clin Case Rep | 2022 |
atrial fibrillation |
| The Preventive Effect of Transcutaneous Electrical Acupoint Stimulation on Postoperative Delirium in Elderly Patients with Time Factors: A Randomized Trial | Ding, L. Ning, J. Guo, Y. Wang, Q. Kou, S. Ke, H. Zhou, R. Yu, B. | J Integr Complement Med | 2022 |
inflammation response |
| Prophylactic use of ramelteon for delirium in hospitalized patients: A systematic review and meta-analyses | Dang, V. Mansukhani, M. P. Wang, Z. Vesely, E. K. Kolla, B. P. | J Acad Consult Liaison Psychiatry | 2022 |
Delirium |
| Longest and largest cohort study of delirium to date reinforces association while causation remains elusive | Cunningham, E. | J Neurol Neurosurg Psychiatry | 2022 |
Cognition |
| Documentation and Diagnosis of Delirium in Parkinson's Disease | Cullinan, R. J. Richardson, S. J. Yarnall, A. J. Burn, D. J. Allan, L. M. Lawson, R. A. | Acta Psychiatr Scand | 2022 |
Confusion |
| Avoiding pitfalls in the treatment of delirium | Chuang, Y. C. Lin, C. Y. Wang, J. K. | Aust N Z J Psychiatry | 2022 |
*Delirium/drug therapy |
| Less pharmacotherapy is more in delirium | Chou, S. T. Pogach, M. Rock, L. K. | Intensive Care Med | 2022 |
*Antipsychotic Agents/therapeutic use |
| Accuracies of Training Labels and Machine Learning Models: Experiments on Delirium and Simulated Data | Cheng, Y. Shao, Y. Rudolph, J. Weir, C. R. Sahlmann, B. Zeng-Treitler, Q. | Stud Health Technol Inform | 2022 |
*Delirium |
| E4BP4 Coordinates Circadian Control of Cognition in Delirium | Chen, M. Zhang, L. Shao, M. Du, J. Xiao, Y. Zhang, F. Zhang, T. Li, Y. Zhou, Q. Liu, K. Wang, Z. Wu, B. | Adv Sci (Weinh) | 2022 |
E4bp4 |
| Association Between Anesthetics and Postoperative Delirium in Elderly Patients Undergoing Spine Surgery: Propofol Versus Sevoflurane | Chang, J. E. Min, S. W. Kim, H. Won, D. Lee, J. M. Kim, T. K. Kim, C. Hwang, J. Y. | Global Spine J | 2022 |
anesthesia |
| Validation of a delirium predictive model in patients admitted to surgical intensive care units: a multicentre prospective observational cohort study | Chaiwat, O. Chittawatanarat, K. Mueankwan, S. Morakul, S. Dilokpattanamongkol, P. Thanakiattiwibun, C. Siriussawakul, A. | BMJ Open | 2022 |
Adult |
| Lidocaine Infusion for the Management of Postoperative Pain and Delirium (LIMPP): protocol for a randomised control trial | Buren, M. A. Theologis, A. Zuraek, A. Behrends, M. Clark, A. J. Leung, J. M. | BMJ Open | 2022 |
Aged |
| Factors influencing resilience to postoperative delirium in adults undergoing elective orthopaedic surgery | Bowman, E. M. L. Cardwell, C. McAuley, D. F. McGuinness, B. Passmore, A. P. Beverland, D. Zetterberg, H. Schott, J. M. Cunningham, E. L. | Br J Surg | 2022 | |
| Delirium prediction in the ICU: designing a screening tool for preventive interventions | Bhattacharyya, A. Sheikhalishahi, S. Torbic, H. Yeung, W. Wang, T. Birst, J. Duggal, A. Celi, L. A. Osmani, V. | JAMIA Open | 2022 |
artificial intelligence |
| Regional vs General Anesthesia and Incidence of Postoperative Delirium in Older Patients Undergoing Hip Fracture Surgery | Zhu, Z. Cao, P. Lin, L. | Jama | 2022 |
Aged |
| Melatonin intervention to prevent delirium in hospitalized patients: A meta-analysis | You, W. Fan, X. Y. Lei, C. Nie, C. C. Chen, Y. Wang, X. L. | World J Clin Cases | 2022 |
Delirium |
| Preoperative Low Physical Activity is a Predictor of Postoperative Delirium in Patients with Gastrointestinal Cancer: A Retrospective Study | Yanagisawa, T. Tatematsu, N. Horiuchi, M. Migitaka, S. Yasuda, S. Itatsu, K. Kubota, T. Sugiura, H. | Asian Pac J Cancer Prev | 2022 |
Activities of Daily Living |
| What is It Like to be Delirious? | Wijdicks, E. F. M. Rabinstein, A. A. | Neurocrit Care | 2022 |
Definitions |
| Impact of Pain, Agitation, and Delirium Bundle on Delirium and Cognitive Function | Wang, X. P. Lv, D. Chen, Y. F. Chen, N. Li, X. D. Xu, C. F. Li, Y. Tian, L. | J Nurs Res | 2022 | |
| Regional vs General Anesthesia and Incidence of Postoperative Delirium in Older Patients Undergoing Hip Fracture Surgery | Uzoigwe, C. E. Campbell-Jones, F. | Jama | 2022 |
Aged |
| Improving delirium screening in older adults at the Royal United Hospital, Bath | Trew, C. A. Cross, R. Howell, K. Dyer, C. | Br J Hosp Med (Lond) | 2022 |
Aged |
| Assessing prevalence and independent predictors of postoperative delirium in patients with head and neck cancer | Tian, T. Xue, F. S. Shao, L. J. Z. Hu, B. | Br J Oral Maxillofac Surg | 2022 |
*Delirium/epidemiology/etiology |
| Delirium due to hip fracture is associated with activated immune-inflammatory pathways and a reduction in negative immunoregulatory mechanisms | Thisayakorn, P. Thipakorn, Y. Tantavisut, S. Sirivichayakul, S. Maes, M. | BMC Psychiatry | 2022 |
Aged |
| Retrospective evaluation of a delirium order set utilizing nonpharmacologic and pharmacologic interventions for the treatment of delirium in medical intensive care unit patients | Taylor, A. D. Chen, A. Reddy, A. J. Lewandowski, A. Torbic, H. | Am J Health Syst Pharm | 2022 |
Adolescent |
| Prevention of dexmedetomidine on postoperative delirium and early postoperative cognitive dysfunction in elderly patients undergoing hepatic lobectomy | Tang, Y. Wang, Y. Kong, G. Zhao, Y. Wei, L. Liu, J. | Zhong Nan Da Xue Xue Bao Yi Xue Ban | 2022 |
Aged |
| Prevalence, clinical features, and risk factors of delusions in patients with delirium | Tachibana, M. Inada, T. Ichida, M. Ozaki, N. | Int J Geriatr Psychiatry | 2022 | |
| Effect of sedative premedication with oral midazolam on postanesthesia care unit delirium in older adults: a secondary analysis following an uncontrolled before-after design | Stuff, K. Kainz, E. Kahl, U. Pinnschmidt, H. Beck, S. von Breunig, F. Nitzschke, R. Funcke, S. Zöllner, C. Fischer, M. | Perioper Med (Lond) | 2022 |
Anesthesia |
| Associations of Smoking With Delirium and Opioid Use in Older Adults With Traumatic Hip Fracture | Salottolo, K. Meinig, R. Fine, L. Kelly, M. Madayag, R. Ekengren, F. Tanner, A., 2nd Bar-Or, D. | J Am Acad Orthop Surg Glob Res Rev | 2022 |
Aged |
| Impact of delirium on mortality in patients hospitalized for heart failure | Ritchie, C. Walters, R. W. Ramaswamy, S. Alla, V. M. | Int J Psychiatry Med | 2022 |
Aged |
| Risk for post-operative delirium related to comorbidities in older adult cardiac patients: An integrative review | Ramos, M. D. Vergara, F. H. Shackleford, J. Briggs, C. Gomez, C. Mofazali, M. Preston, J. | J Clin Nurs | 2022 |
cardiac surgery |