Delirium Bibliography

Delirium Bibliography books graphicWhat is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!

How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.

Reference Information

Title
Acute Brain Dysfunction: Development and Validation of a Daily Prediction Model.
Authors
Marra, A. Pandharipande, P. P. Shotwell, M. S. Chandrasekhar, R. Girard, T. D. Shintani, A. K. Peelen, L. M. Moons, K. Dittus, R. S. Ely, E. W. Vasilevskis, E. E.
Year
2018
Journal
Chest
Abstract

BACKGROUND: To develop and validate a dynamic risk model to predict daily changes in acute brain dysfunction (i.e., delirium and coma), discharge and mortality in intensive care unit (ICU) patients. METHODS: Using data from a multicenter prospective ICU cohort, we developed a daily Acute Brain Dysfunction-prediction model (ABD-pm) using multinomial logistic regression that estimated 15 transition probabilities (from 1 of 3 brain function states [normal, delirious, or comatose] to 1 of 5 possible outcomes [normal, delirious, comatose, ICU discharge, and dead]) using baseline and daily risk factors. Model discrimination was assessed using predictive characteristics such as negative predictive value [NPV]. Calibration was assessed by plotting empirical versus model-estimated probabilities. Internal validation was performed by bootstrap procedure. RESULTS: We analyzed data from 810 patients (6711 daily transitions). The ABD-pm included individual risk factors: mental status, age, pre-existing cognitive impairment, baseline and daily severity of illness, and daily administration of sedatives. The model yielded very high NPVs for “next day” delirium (NPV=0.823), coma (NPV= 0.892), normal cognitive state (NPV=0.875), ICU discharge (NPV=0.905), and mortality (NPV=0.981). The model demonstrated outstanding calibration when predicting the total number of patients expected to be in any given state across predicted risk. CONCLUSIONS: We developed and internally validated a dynamic risk model that predicts the daily risk for one of three cognitive states, ICU discharge, or mortality. The ABD-pm may be useful for predicting the proportion of patients for each outcome state across entire ICU populations to guide quality, safety, and care delivery activities.

PMID

29580772

Keywords

Coma
Delirium
Intensive Care Unit
Mortality
Prediction

Page(s)
Issue

Search:
Total Records Found: 6016, showing 100 per page
TitleAuthorsJournalYearKeywords
The inter-relationship between delirium and dementia: the importance of delirium prevention Fong, T. G. Inouye, S. K. Nat Rev Neurol 2022
Five-Year Outcomes After Implementing a Pain, Agitation, and Delirium Protocol in a Mixed Intensive Care Unit Fish, J. T. Baxa, J. T. Draheim, R. R. Willenborg, M. J. Mills, J. C. Sticht, L. A. Hankwitz, J. L. Wells, J. A. Jung, H. S. J Intensive Care Med 2022

Adult
Analgesics/therapeutic use
*Delirium/drug therapy
Humans
Hypnotics and Sedatives/therapeutic use
Intensive Care Units
Length of Stay
Pain/drug therapy
Respiration, Artificial
Retrospective Studies
analgesics
cost analysis
costs
critical care
hypnotics and sedatives
protocol

Improving Delirium Assessments in Vanderbilt Pediatric and Pediatric Cardiovascular Intensive Care Units Eken, H. N. Betters, K. A. Fuchs, D. C. Smith, H. A. B. Williams, S. R. Pediatr Qual Saf 2022
Outcomes in Post-operative Delirium Following Bowel Resection: A Single Center Retrospective Review Desrochers, R. M. Lynch, L. J. Gates, J. D. Ricaurte, D. Wade, J. T. Dicks, R. S. Keating, J. J. J Surg Res 2022

Bowel
Delirium
Elective
Emergency
Mortality
Resection

Efficacy and Safety of Remimazolam Besylate versus Dexmedetomidine for Sedation in Non-Intubated Older Patients with Agitated Delirium After Orthopedic Surgery: A Randomized Controlled Trial Deng, Y. Qin, Z. Wu, Q. Liu, L. Yang, X. Ju, X. Zhang, Y. Liu, L. Drug Des Devel Ther 2022

Benzodiazepines
*Delirium/drug therapy
*Dexmedetomidine/adverse effects
Humans
Hypnotics and Sedatives/adverse effects
*Orthopedic Procedures
agitation
delirium
dexmedetomidine
older adult
orthopedics
remimazolam besylate

Delirium, changes in cognitive function, and risk of diagnosed dementia after kidney transplantation Chu, N. M. Bae, S. Chen, X. Ruck, J. Gross, A. L. Albert, M. Neufeld, K. J. Segev, D. L. McAdams-DeMarco, M. A. Am J Transplant 2022

clinical research/practice
cognitive function
delirium
epidemiology
health services and outcomes research
kidney disease
kidney transplant
kidney transplantation/nephrology
mental health
neurology

Bispectral Index (BIS) Monitoring and Postoperative Delirium in Elderly Patients Undergoing Surgery: A Systematic Review and Meta-Analysis With Trial Sequential Analysis Chew, W. Z. Teoh, W. Y. Sivanesan, N. Loh, P. S. Shariffuddin,, II Ti, L. K. Ng, K. T. J Cardiothorac Vasc Anesth 2022

Bis
elderly
meta-analysis
postoperative cognitive dysfunction
postoperative delirium
systematic review

Delirium prevalence in geriatric emergency department patients: A systematic review and meta-analysis Chen, F. Liu, L. Wang, Y. Liu, Y. Fan, L. Chi, J. Am J Emerg Med 2022

Aged
*Delirium/diagnosis/epidemiology
Emergency Service, Hospital
Humans
Mass Screening
Prevalence
Delirium
Meta-analysis
Older adults

Improving quantification of anticholinergic burden using the Anticholinergic Effect on Cognition Scale - a healthcare improvement study in a geriatric ward setting Balasundaram, B. Ang, W. S. T. Stewart, R. Bishara, D. Ooi, C. H. Li, F. Akram, F. Eu Kwek, A. B. Australas Psychiatry 2022

Aged
*Cholinergic Antagonists/adverse effects
Cognition
*Cognition Disorders
Delivery of Health Care
Hospitals
Humans
anticholinergic burden scales
anticholinergic drugs
anticholinergic effect on cognition scale
delirium
dementia

The Association of Selective Serotonin Reuptake Inhibitors With Delirium in Critically Ill Adults: A Secondary Analysis of the Bringing to Light the Risk Factors and Incidence of Neuropsychologic Dysfunction in ICU Survivors ICU Study Austin, C. A. Yi, J. Lin, F. C. Pandharipande, P. Ely, E. W. Busby-Whitehead, J. Carson, S. S. Crit Care Explor 2022

delirium
intensive care unit outcomes
neurophysiology
neurotransmitters
selective serotonin reuptake inhibitors
interest.

Parental Education and Delirium Risk after Surgery in Older Adults Arias, F. Chen, F. Shiff, H. Marcantonio, E. R. Jones, R. N. Schmitt, E. M. Metzger, E. Fong, T. G. Travison, T. G. Inouye, S. K. Clin Gerontol 2022

Childhood socioeconomic status
delirium
social determinants of health

Informing the standardising of care for prolonged stay patients in the ICU: A scoping review of quality improvement tools Allum, L. Apps, C. Pattison, N. Connolly, B. Rose, L. Intensive Crit Care Nurs 2022

Bundle
Care standardisation
Checklist
Critical care
Persistent or chronic critical illness
Quality improvement

Monitoring of nighttime EEG slow-wave activity during dexmedetomidine infusion in patients with hyperactive ICU delirium: An observational pilot study Ala-Kokko, T. Erikson, K. Koskenkari, J. Laurila, J. Kortelainen, J. Acta Anaesthesiol Scand 2022

C-trend
Rcsq
sleep

Development of a Delirium Risk Predication Model among ICU Patients in Oman Al-Hoodar, R. K. Lazarus, E. R. Alomari, O. Alzaabi, O. Anesthesiol Res Pract 2022
Comparison Between Deltascan Single Channel Electroencephalography (EEG), Confusion Assessment Method-Intensive Care Unit (CAM-ICU) Score and Clinical Assessment in Diagnosing Delirium in Intubated Patients in the Intensive Care Unit Aben, J. Pouwels, S. Oldenbeuving, A. Cureus 2022

cam-icu
complications
delirium
electroencephalography
intensive care
monitoring

A Cross-Sectional Survey on the Clinical Management of Emergence Delirium in Adults: Knowledge, Attitudes, and Practice in Mainland China Yuan, Y. Lei, B. Li, Z. Wang, X. Zhao, H. Gao, M. Xue, Y. Zhang, W. Xiao, R. Meng, X. Zheng, H. Zhang, J. Wang, G. Guo, X. Brain Sci 2022

Pacu
anesthesia nurse
emergence delirium

Development and Validation of a Nomogram for Predicting Postoperative Delirium in Patients With Elderly Hip Fracture Based on Data Collected on Admission Yang, Y. Wang, T. Guo, H. Sun, Y. Cao, J. Xu, P. Cai, Y. Front Aging Neurosci 2022

albumin
chronic obstructive pulmonary disease
dementia
elderly hip fracture
nomogram
postoperative delirium
prediction model

Preoperative Inflammatory Markers and the Risk of Postoperative Delirium in Patients Undergoing Lumbar Spinal Fusion Surgery Yang, J. S. Lee, J. J. Kwon, Y. S. Kim, J. H. Sohn, J. H. J Clin Med 2022

CRP-to-albumin ratio
monocyte-to-lymphocyte ratio
neutrophil-to-lymphocyte ratio
postoperative delirium
spine surgery

An association between cancer type and delirium incidence in Japanese elderly patients: A retrospective longitudinal study Yamato, K. Ikeda, A. Endo, M. Filomeno, R. Kiyohara, K. Inada, K. Nishimura, K. Tanigawa, T. Cancer Med 2022

cancer
delirium
longitudinal study

Increased Direct Current-Electroencephalography Shifts During Induction of Anesthesia in Elderly Patients Developing Postoperative Delirium Windmann, V. Dreier, J. P. Major, S. Spies, C. Lachmann, G. Koch, S. Front Aging Neurosci 2022

*dc-eeg
*anesthesia induction
*blood–brain barrier
*direct current EEG
*electroencephalography
*hyperventilation
*postoperative delirium (POD)

Risk factors of delirium after gastrointestinal surgery: A meta-analysis Wang, X. Yu, D. Du, Y. Geng, J. J Clin Nurs 2022

delirium
gastrointestinal
risk factor

Physician Experience Design (PXD): More Usable Machine Learning Prediction for Clinical Decision Making Wang, L. Chignell, M. Zhang, Y. Pinto, A. Razak, F. Sheehan, K. Verma, A. AMIA Annu Symp Proc 2022

Artificial Intelligence
Clinical Decision-Making
Decision Making
*Delirium
Humans
Machine Learning
*Physicians/psychology

The Relationship Between Cardiovascular Disease Risk Score and Postoperative Delirium: The PNDABLE Study Wang, J. Wang, L. Tang, X. Wang, F. Liu, S. Wu, X. Dong, R. Lin, X. Wang, B. Bi, Y. Front Aging Neurosci 2022

biomarkers
cerebrospinal fluid
mediation analysis
postoperative delirium
vascular risk score
commercial or financial relationships that could be construed as a potential
conflict of interest.

Preoperative intervention to prevent delirium in patients with hip fracture - a systematic review Virsøe-Frandsen, C. D. Skjold, C. Wildgaard, K. Møller, A. M. Dan Med J 2022

Aged
*Delirium/etiology/prevention & control
Geriatric Assessment
*Hip Fractures/surgery
Humans
Odds Ratio
Preoperative Care

Coexisting delirium and excited catatonia Vellanki, K. D. Carroll, B. T. Ann Clin Psychiatry 2022

*Antipsychotic Agents/therapeutic use
*Catatonia
*Delirium/drug therapy
Humans

Confusion regarding the use of Natural Language Processing in ICU delirium assessment van Diem-Zaal, I. J. van den Boogaard, M. Kotfis, K. Ely, E. W. Intensive Care Med 2022

*Delirium/diagnosis
Humans
Intensive Care Units
*Natural Language Processing
Reproducibility of Results

Postoperative delirium and changes in the blood-brain barrier, neuroinflammation, and cerebrospinal fluid lactate: a prospective cohort study Taylor, J. Parker, M. Casey, C. P. Tanabe, S. Kunkel, D. Rivera, C. Zetterberg, H. Blennow, K. Pearce, R. A. Lennertz, R. C. Sanders, R. D. Br J Anaesth 2022

Biomarkers
*Blood-Brain Barrier
*Delirium/diagnosis
Humans
Interleukin-6
Lactic Acid
Neuroinflammatory Diseases
Prospective Studies
S100 Calcium Binding Protein beta Subunit/cerebrospinal fluid
*delirium
*dementia
*inflammation
*neuronal injury
*older adults
*surgery

Prospective clinical intervention study of aripiprazole and risperidone in the management of postoperative delirium in elderly patients after cardiovascular surgery Sugawara, H. Koyama, A. Maruyama, T. Koda, Y. Fukunaga, H. Ishikawa, T. Takebayashi, M. Okamoto, K. Fukui, T. Hashimoto, M. Psychiatry Clin Neurosci 2022
A simple risk score list can be used to predict the occurrence of delirium in patients admitted to inpatient hospice care: A medical record study Stoevelaar, R. Juffermans, C. C. M. Roorda, I. M. M. de Nijs, E. J. M. Hoornweg, J. Cannegieter, S. C. van der Linden, Y. M. Eur J Cancer Care (Engl) 2022

delirium
end-of-life care
hospice and palliative care nursing
hospice care
retrospective studies
terminal care

Chemokines in ICU Delirium: An Exploratory Study Smith, R. J. Rabinstein, A. A. Cartin-Ceba, R. Singh, V. P. Lachner, C. Khatua, B. Trivedi, S. Gajic, O. Crit Care Explor 2022

chemokine
cytokine
delirium
inflammation
intensive care unit
interest.

Cytokine profiles in intensive care unit delirium Smith, R. J. Lachner, C. Singh, V. P. Trivedi, S. Khatua, B. Cartin-Ceba, R. Acute Crit Care 2022

cytokine
delirium
encephalopathy
intensive care unit
neuroinflammation

Edmonton frailty scale score predicts postoperative delirium: a retrospective cohort analysis Sieber, F. Gearhart, S. Bettick, D. Wang, N. Y BMC Geriatr 2022

Cohort Studies
*Delirium/diagnosis/epidemiology/etiology
*Frailty/complications/diagnosis
Humans
Postoperative Complications/diagnosis/epidemiology/etiology
Prospective Studies
Retrospective Studies
Risk Factors
*Complications
*Delirium
*Elective surgical procedures
*Frailty
*Postoperative

Observation of Anesthetic Effect of Dexmedetomidine Combined With Intraspinal Anesthesia in Hip Arthroplasty and its Effect on Postoperative Delirium and Stress Response Shen, Y. Wang, C. Zhong, X. Wu, Y. He, X. Front Surg 2022

anesthetic effects
delirium
dexmedetomidine
hip replacement
immunologic function
intraspinal anesthesia
stress response
commercial or financial relationships that could be construed as a potential
conflict of interest.

Postoperative Application of Dexmedetomidine is the Optimal Strategy to Reduce the Incidence of Postoperative Delirium After Cardiac Surgery: A Network Meta-Analysis of Randomized Controlled Trials Shang, L. Hou, M. Guo, F. Ann Pharmacother 2022

cardiac surgery
cognitive dysfunction
dexmedetomidine
network meta-analysis
postoperative delirium

Decreasing delirium through music listening (DDM) in critically ill, mechanically ventilated older adults in the intensive care unit: a two-arm, parallel-group, randomized clinical trial Seyffert, S. Moiz, S. Coghlan, M. Balozian, P. Nasser, J. Rached, E. A. Jamil, Y. Naqvi, K. Rawlings, L. Perkins, A. J. Gao, S. Hunter, J. D., 3rd Khan, S. Heiderscheit, A. Chlan, L. L. Khan, B. Trials 2022

Aged
Critical Illness/psychology
*Delirium/diagnosis/prevention & control
Humans
Intensive Care Units
*Music
Pain
Respiration, Artificial/adverse effects
Acute respiratory failure
Anxiety
Cognition
Delirium
Intensive care unit
Mechanical ventilation
Music
Post-intensive care syndrome

Prevention of delirium with agitation by yokukansan in older adults after cancer surgery Sadahiro, R. Wada, S. Matsuoka, Y. J. Uchitomi, Y. Yamaguchi, T. Sato, T. Esaki, M. Yoshimoto, S. Daiko, H. Kanemitsu, Y. Kawai, A. Kato, T. Fujimoto, H. Uezono, Y. Shimizu, K. Matsuoka, H. Jpn J Clin Oncol 2022

clinical trial
gerontology
psycho-oncology
surgical oncology

Midazolam impacts acetyl-And butyrylcholinesterase genes: An epigenetic explanation for postoperative delirium? Rump, K. Holtkamp, C. Bergmann, L. Nowak, H. Unterberg, M. Orlowski, J. Thon, P. Bazzi, Z. Bazzi, M. Adamzik, M. Koos, B. Rahmel, T. PLoS One 2022

Acetylcholinesterase/metabolism
Butyrylcholinesterase
Cholinesterase Inhibitors/pharmacology
*Delirium/etiology
Epigenesis, Genetic
Histone Demethylases/metabolism
Histones/metabolism
Humans
Leukocytes, Mononuclear/metabolism
Lysine/metabolism
Midazolam/pharmacology
*Neuroblastoma/genetics

Ren, X. Zhang, S. Yang, Y. Song, A. Liang, F. Zhang, Y. Dong, Y. Wu, X. Xie, Z. Ketamine Induces Delirium-Like Behavior and Interferes With Endosomal Tau Trafficking Anesth Analg 2022
The crucial factors influencing the development and outcomes of postoperative delirium in proximal femur fractures Rajeev, A. Railton, C. Devalia, K. Aging Med (Milton) 2022

delirium
development
outcomes
postoperative
proximal femur fractures

Neuromonitoring depth of anesthesia and its association with postoperative delirium Pérez-Otal, B. Aragón-Benedí, C. Pascual-Bellosta, A. Ortega-Lucea, S. Martínez-Ubieto, J. Ramírez-Rodríguez, J. M. Sci Rep 2022

Anesthesia, General/adverse effects
*Anesthesiology
*Anesthetics
*Delirium/etiology/prevention & control
Humans
Postoperative Complications/epidemiology/etiology/prevention & control

Improving the Detection, Assessment, Management and Prevention of Delirium in Hospices (the DAMPen-D study): protocol for a co-design and feasibility study of a flexible and scalable implementation strategy to deliver guideline-adherent delirium care Pearson, M. Jackson, G. Jackson, C. Boland, J. Featherstone, I. Huang, C. Ogden, M. Sartain, K. Siddiqi, N. Twiddy, M. Johnson, M. BMJ Open 2022

*Delirium/diagnosis/prevention & control
Delivery of Health Care
Feasibility Studies
*Hospices
Humans
Wales
*delirium & cognitive disorders
*palliative care
*protocols & guidelines

An Interdisciplinary Reappraisal of Delirium and Proposed Subtypes Oldham, M. A. Slooter, A. J. C. Ely, E. W. Crone, C. Maldonado, J. R. Rosenthal, L. J. J Acad Consult Liaison Psychiatry 2022

acute encephalopathy
altered mental status
delirium disorder
neuropsychiatric symptoms
pathophysiology
subtypes

Postoperative Delirium in Patients with Oral Cancer: Is Intraoperative Fluid Administration a Neglected Risk Factor? Obermeier, K. T. Kraus, M. Smolka, W. Henkel, J. Saller, T. Otto, S. Liokatis, P. Cancers (Basel) 2022

fluid balance
fluid management
head and neck surgery
oral cancer
postoperative delirium

Risk of delirium associated with antimuscarinics in older adults: A case-time-control study Nishtala, P. S. Chyou, T. Y. Pharmacoepidemiol Drug Saf 2022

Aged
Aged, 80 and over
Cholinergic Antagonists
*Delirium/chemically induced/drug therapy/epidemiology
Humans
Muscarinic Antagonists/adverse effects
Solifenacin Succinate/adverse effects
*Urinary Bladder, Overactive/chemically induced
*adverse effects
*antimuscarinics
*delirium
*elderly
*pharmacoepidemiology

Potential effects of regular use of antihypertensive drugs for in-hospital delirium in geriatric patients with trauma Nagasawa, H. Omori, K. Ota, S. Muramatsu, K. I. Ishikawa, K. Yanagawa, Y. Sci Rep 2022

Aged
*Antihypertensive Agents/therapeutic use
*Delirium/drug therapy/epidemiology/etiology
Hospital Mortality
Hospitals
Humans
Retrospective Studies

Performance of Melatonin as Prophylaxis in Geriatric Patients with Multifactorial Risk for Postoperative Delirium Development: A Randomized Comparative Study Mohamed, S. A. Rady, A. Youssry, M. Abdelaziz Mohamed, M. R. Gamal, M. Turk J Anaesthesiol Reanim 2022
Perioperative risk factors associated with increased incidence of postoperative delirium: systematic review, meta-analysis, and Grading of Recommendations Assessment, Development, and Evaluation system report of clinical literature Mevorach, L. Forookhi, A. Farcomeni, A. Romagnoli, S. Bilotta, F. Br J Anaesth 2022

Grade
delirium
intensive care unit
meta-analysis
perioperative
postoperative
review
risk factors

Delirium in ICU Patients after Cardiac Arrest: A Scoping Review Mędrzycka-Dąbrowska, W. Lange, S. Religa, D. Dąbrowski, S. Friganović, A. Oomen, B. Krupa, S. J Pers Med 2022

Icu
a scoping review
cardiac arrest
delirium
resuscitation

Epidemiology of delirium in hospitalized patients in Latin America: A systematic review Maximiliano, B. Sebastian, B. Estefania, A. Irma, C. Gutierrez, P. Daniela, P. Pv Roberta, C. Eduardo, T. Jose, M. Felipe, S. Acta Psychiatr Scand 2022

Latin America
acute confusional syndrome
delirium
incidence
prevalence

Effect of Perioperative Dexmedetomidine Infusion on Postoperative Delirium in Elderly Patients Undergoing Oral and Maxillofacial Surgery: A Randomized Controlled Clinical Trial Liu, T. Tuo, J. Wei, Q. Sun, X. Zhao, H. Zhao, X. Qu, M. Int J Gen Med 2022

dexmedetomidine
elderly
oral and maxillofacial surgery
postoperative delirium

Type 2 Diabetes Mellitus with Tight Glucose Control and Poor Pre-Injury Stair Climbing Capacity May Predict Postoperative Delirium: A Secondary Analysis Liu, K. Song, Y. Yuan, Y. Li, Z. Wang, X. Zhang, W. Li, Y. Mi, X. Han, D. Rong, Y. Guo, X. Wang, G. Brain Sci 2022

glycemic control
hip fracture
physical performance
postoperative delirium
type 2 diabetes mellitus

Preoperative Plasma Tau-PT217 and Tau-PT181 Are Associated With Postoperative Delirium Liang, F. Baldyga, K. Quan, Q. Khatri, A. Choi, S. Wiener-Kronish, J. Akeju, O. Westover, B. M. Cody, K. Shen, Y. Marcantonio, E. R. Xie, Z. Ann Surg 2022
Development and Validation of Simplified Delirium Prediction Model in Intensive Care Unit Kim, M. K. Oh, J. Kim, J. J. Park, J. Y. Front Psychiatry 2022

critical care
delirium
intensive care unit
prediction model
simplified model
commercial or financial relationships that could be construed as a potential
conflict of interest.

The effects of hypomagnesemia on delirium in middle-aged and older adult patients admitted to medical intensive care units Kim, J. Y. Lee, H. J. Lee, H. Y. Lee, S. M. Lee, J. Park, T. Y. Acute Crit Care 2022

delirium
hypomagnesemia
intensive care unit

Structural integrity of the anterior mid-cingulate cortex contributes to resilience to delirium in SuperAging Katsumi, Y. Wong, B. Cavallari, M. Fong, T. G. Alsop, D. C. Andreano, J. M. Carvalho, N. Brickhouse, M. Jones, R. Libermann, T. A. Marcantonio, E. R. Schmitt, E. Shafi, M. M. Pascual-Leone, A. Travison, T. Barrett, L. F. Inouye, S. K. Dickerson, B. C. Tou Brain Commun 2022

Mri
cortical thickness
postoperative delirium
salience network
successful aging

"Excited delirium," erroneous concepts, dehumanizing language, false narratives, and threat to Black lives Fiscella, K. Pinals, D. A. Shields, C. G. Acad Emerg Med 2022

*Delirium/diagnosis
Humans
*Language

Knowing the Older Adult With Delirium Superimposed on Dementia Fick, D. M. Am J Geriatr Psychiatry 2022

Delirium
aging
dementia
detection

Bibliometric Analysis of 100 Most-Cited Articles in Delirium Fei, X. Zeng, Q. Wang, J. Gao, Y. Xu, F. Front Psychiatry 2022

bibliometric analysis
bibliometrics
cognitive disorder
delirium
psychiatry
top-100
commercial or financial relationships that could be construed as a potential
conflict of interest.

Transcutaneous Electrical Acupoint Stimulation Combined With Auricular Acupressure Reduces Postoperative Delirium Among Elderly Patients Following Major Abdominal Surgery: A Randomized Clinical Trial Fan, Q. Lei, C. Wang, Y. Yu, N. Wang, L. Fu, J. Dong, H. Lu, Z. Xiong, L. Front Med (Lausanne) 2022

abdominal surgery
auricular acupressure
delirium
elderly
transcutaneous electric acupoint stimulation
commercial or financial relationships that could be construed as a potential
conflict of interest.

Depression is associated with delirium after cardiac surgery-a population-based cohort study Falk, A. Kåhlin, J. Nymark, C. Hultgren, R. Stenman, M. Interact Cardiovasc Thorac Surg 2022

Aged
*Cardiac Surgical Procedures/adverse effects
Cohort Studies
*Delirium/diagnosis/epidemiology/etiology
Depression/diagnosis/epidemiology
Humans
Postoperative Complications/etiology
Prospective Studies
Risk Factors
Cardiac surgery
Depression
Patient Health Questionnaire-9
Postoperative delirium
Screening

Association of delirium screening on hospitalized adults and postacute care utilization: A retrospective cohort study Dulin, J. D. Zhang, J. Marsden, J. Mauldin, P. D. Moran, W. P. Kalivas, B. C. Am J Med Sci 2022
Adaptation, implementation, and mixed methods evaluation of an interprofessional modular clinical practice guideline for delirium management on an inpatient palliative care unit Bush, S. H. Skinner, E. Lawlor, P. G. Dhuper, M. Grassau, P. A. Pereira, J. L. MacDonald, A. R. Parsons, H. A. Kabir, M. BMC Palliat Care 2022

Adult
*Delirium/therapy
Focus Groups
*Hospice and Palliative Care Nursing
Humans
Inpatients
Palliative Care
Clinical practice guideline
Delirium
Educational activities
Implementation
Interprofessional
Knowledge translation
Learning
Mixed methods
Quality improvement

Older age, delirium, dementia, frailty, and critical care: Care priorities Bloomer, M. J. Woszczeiko, C. Hutchinson, A. M. Intensive Crit Care Nurs 2002

Critical care
Delirium
Dementia
Frail elderly
Intensive care

Early Diagnosis of Delirium in Palliative Care Patients Decreases Mortality and Necessity of Palliative Sedation: Results of a Prospective Observational Study Beretta, M. Uggeri, S. Santucci, C. Cattaneo, M. Ermolli, D. Gerosa, C. Ornaghi, M. Roccasalva, A. Santambrogio, P. Varrassi, G. Corli, O. Cureus 2022

clinical outcome
delirium
early diagnosis
end of life
mortality
palliative care

Incidence and associations of hospital delirium diagnoses in 85,979 people with severe mental illness: A data linkage study Bauernfreund, Y. Launders, N. Favarato, G. Hayes, J. F. Osborn, D. Sampson, E. L. Acta Psychiatr Scand 2022

bipolar disorder
databases
delirium
psychotic disorders
schizophrenia

The Pharmacogenetics of Opiates and Its Impact on Delirium in Mechanically Ventilated Adults: A Pilot Study Austin, C. A. Szeto, A. Gupta, A. Wiltshire, T. Crona, D. J. Kistler, C. J Pharm Technol 2022

analgesics
delirium
genetics
intensive care unit
opioids
pharmacogenetics
conflicts of interest with respect to the research, authorship, and/or
publication of this article.

Agents intervening against delirium in the intensive care unit trial-Protocol for a secondary Bayesian analysis Andersen-Ranberg, N. Poulsen, L. M. Perner, A. Hästbacka, J. Morgan, M. P. G. Citerio, G. Oxenbøll-Collet, M. Weber, S. O. Andreasen, A. S. Bestle, M. H. Uslu, B. Pedersen, H. B. S. Nielsen, L. G. Damgaard, K. Jensen, T. B. Sommer, T. Dey, N. Mathiesen, Acta Anaesthesiol Scand 2022

Adult
*Antipsychotic Agents/therapeutic use
Bayes Theorem
*Delirium/drug therapy
Haloperidol/therapeutic use
Humans
Intensive Care Units
Bayesian statistics
Delirium
Icu
haloperidol

Increased Direct Current-Electroencephalography Shifts During Induction of Anesthesia in Elderly Patients Developing Postoperative Delirium Windmann, V. Dreier, J. P. Major, S. Spies, C. Lachmann, G. Koch, S. Front Aging Neurosci 2022

*dc-eeg
*anesthesia induction
*blood–brain barrier
*direct current EEG
*electroencephalography
*hyperventilation
*postoperative delirium (POD)

The Effect of Propofol versus Sevoflurane on Postoperative Delirium in Parkinson's Disease Patients Undergoing Deep Brain Stimulation Surgery: An Observational Study Zhou, Y. Li, Z. Ma, Y. Yu, C. Chen, Y. Ding, J. Yu, J. Zhou, R. Wang, X. Liu, T. Guo, X. Fan, T. Shi, C. Brain Sci 2022

Parkinson’s disease
anesthesia maintenance
postoperative delirium
propofol
sevoflurane

Association between smoking and postoperative delirium in surgical patients with pulmonary hypertension: a secondary analysis of a cohort study Zhou, S. Shi, S. Xie, C. Chen, G. BMC Psychiatry 2022

Cohort Studies
*Delirium/epidemiology
Humans
*Hypertension, Pulmonary/complications
Postoperative Complications/epidemiology/etiology
Prospective Studies
Smoking/adverse effects
*Postoperative delirium
*Pulmonary hypertension
*Smoking

Comorbidity patterns in institutionalized older adults affected by dementia Zazzara, M. B. Vetrano, D. L. Carfì, A. Liperoti, R. Damiano, C. Onder, G. Alzheimers Dement (Amst) 2022

care pathways
dementia comorbidities
nursing homes
older adults
personalized medicine

The Impact of Perioperative and Predisposing Risk Factors on the Development of Postoperative Delirium and a Possible Gender Difference Wittmann, M. Kirfel, A. Jossen, D. Mayr, A. Menzenbach, J. Geriatrics (Basel) 2022

gender difference
older adults
postoperative delirium
risk factors

Four-in-One: A Comprehensive Checklist for the Assessment of Pain, Undersedation, Iatrogenic Withdrawal and Delirium in the PICU: A Delphi Study van Dijk, M. Ista, E. Front Pediatr 2022

Iws
delirium
distress
pain assessment
pediatric intensive care unit
undersedation
commercial or financial relationships that could be construed as a potential
conflict of interest.

Analgesia, Sedation, Paralytics, Delirium, and Iatrogenic Withdrawal Valentine, K. Kummick, J. Pediatr Clin North Am 2022

*Analgesia
Child
Conscious Sedation
Critical Care
Critical Illness/therapy
*Delirium/chemically induced/drug therapy
Humans
Hypnotics and Sedatives/adverse effects
Iatrogenic Disease
Pain/drug therapy
Pain Management
*Critical care pediatrics
*Delirium
*Paralytics
*Sedation
*Withdrawal

Antipsychotic prescribing in people admitted to hospital with dementia or delirium Tumusiime, W. A. Hardman, C. J. Breen, J. L. Australas J Ageing 2022

*Antipsychotic Agents/therapeutic use
*Delirium/diagnosis/drug therapy
*Dementia/diagnosis/drug therapy
Hospitalization
Hospitals
Humans
Retrospective Studies
antipsychotic
delirium
dementia
hospital
psychotropic

Breaking barriers in postoperative delirium Terrando, N. Akassoglou, K. Br J Anaesth 2022

biomarker
blood–brain barrier
cerebrospinal fluid
delirium
fibrinogen
neuroinflammation

The Relationship Between Suboptimal Social Networks and Postoperative Delirium: The PNDABLE Study Tang, X. Yv, H. Wang, F. Wang, J. Liu, S. Wu, X. Dong, R. Lin, X. Wang, B. Bi, Y. Front Aging Neurosci 2022

cerebrospinal fluid
lifestyle
mediating effect
postoperative delirium
social networks
commercial or financial relationships that could be construed as a potential
conflict of interest.

Delirium incidence and risk factors in patients undergoing non-invasive ventilation for acute respiratory failure: a multicenter observational trial Tabbì, L. Tonelli, R. Comellini, V. Dongilli, R. Sorgentone, S. Spacone, A. Paonessa, M. C. Sacchi, M. Falsini, L. Boni, E. Ribuffo, V. Bruzzi, G. Castaniere, I. Fantini, R. Marchioni, A. Pisani, L. Nava, S. Clini, E. Minerva Anestesiol 2022
The association between Monocyte-to-Lymphocyte ratio and postoperative delirium in ICU patients in cardiac surgery Su, X. Wang, J. Lu, X. J Clin Lab Anal 2022

inflammatory markers
medical information Mart for intensive care-III
monocyte-to-lymphocyte ratio
postoperative delirium

Development of a non-pharmacologic delirium management bundle in paediatric intensive care units Stenkjaer, R. L. Herling, S. F. Egerod, I. Weis, J. van Dijk, M. Kudchadkar, S. R. Ramelet, A. S. Ista, E. Nurs Crit Care 2022

delirium
delphi study
management
non-pharmacological
paediatric intensive care unit

Delirium in hospitalised adults with acute burns - A systematic review Stanley, G. H. M. Barber, A. R. J. O'Brien, A. M. Hamill, C. Boardman, G. Frear, C. C. Edgar, D. W. Seymour, H. Wood, F. M. Burns 2022

Burns
Delirium
Intensive care
Meta-analysis
Systematic review

Delirium associated with buprenorphine use in cardiac surgery: A retrospective cohort study Selvaraj, T. Thangavel, P. Siddhaarth, K. Indian J Anaesth 2022

Aged
buprenorphine
coronary artery bypass off-pump
delirium
postoperative pain

Influence of perioperative dexmedetomidine on the incidence of postoperative delirium in adult patients undergoing cardiac surgery Patel, M. Onwochei, D. N. Desai, N. Br J Anaesth 2022

Adult
Bradycardia/epidemiology
*Cardiac Surgical Procedures/adverse effects
*Delirium/epidemiology/prevention & control
*Dexmedetomidine/therapeutic use
Humans
Incidence
Postoperative Complications/epidemiology/prevention & control
*cardiac surgery
*confusion assessment method
*delirium
*dexmedetomidine
*systematic review

Association Between Implementation of a Geriatric Trauma Clinical Pathway and Changes in Rates of Delirium in Older Adults With Traumatic Injury Park, C. Bharija, A. Mesias, M. Mitchell, A. Krishna, P. Storr-Street, N. Brown, A. Martin, M. Lu, A. C. Staudenmayer, K. L. JAMA Surg 2022
Intraoperative hyperoxygenation may negatively affect postoperative cognitive functions in coronary artery bypass graft operations: A randomized controlled study Onur, T. Karaca, Ü Ata, F. Sayan, H. E. Onur, A. Yilmaz, C. Balkaya, A. N. Eriş, C. J Card Surg 2022

cardiopulmonary bypass
cognitive function
hyperoxia
near-infrared
postoperative complications
spectroscopy

Investigation of Risk Factors for Postoperative Delirium after Transcatheter Aortic Valve Implantation: A Retrospective Study Ogata, Y. Kobayashi, N. Yamauchi, M. J Clin Med 2022

aortic stenosis
postoperative delirium
transcatheter aortic valve implantation

Mobilization in the evening to prevent delirium: A pilot randomized trial Nydahl, P. McWilliams, D. Weiler, N. Borzikowsky, C. Howroyd, F. Brobeil, A. Lindner, M. von Haken, R. Nurs Crit Care 2022

Critical Care
*Delirium/prevention & control
Humans
*Intensive Care Units
Pilot Projects
Respiration, Artificial/adverse effects
delirium
early mobilization
intensive care unit
prevention
rehabilitation

Delirium on stroke units: a prospective, multicentric quality-improvement project Nydahl, P. Baumgarte, F. Berg, D. Bergjan, M. Borzikowsky, C. Franke, C. Green, D. Hannig, A. Hansen, H. C. Hauss, A. Hansen, U. Istel, R. Krämer, N. Krause, K. Lohrmann, R. Mohammadzadeh-Vazifeh, M. Osterbrink, J. Palm, F. Petersen, T. Schöller, B. Sto J Neurol 2022

*Delirium/diagnosis/epidemiology/etiology
Humans
Incidence
Postoperative Complications/epidemiology
Prospective Studies
Quality Improvement
Registries
Risk Factors
*Stroke/complications/therapy
Delirium
Encephalopathy
Quality-improvement
Stroke

The relationship of acute delirium with cognitive and psychiatric symptoms after stroke: a longitudinal study Nerdal, V. Gjestad, E. Saltvedt, I. Munthe-Kaas, R. Ihle-Hansen, H. Ryum, T. Lydersen, S. Grambaite, R. BMC Neurol 2022

Aged
Cognition
*Cognitive Dysfunction/etiology
*Delirium/diagnosis/epidemiology/etiology
Female
Humans
Longitudinal Studies
Male
Neuropsychological Tests
Prospective Studies
*Stroke/diagnosis
Anxiety
Cerebrovascular event
Cognitive dysfunction
Confusion
Depression
Mental status and dementia tests
is associate editor in BMC Neurology. None of the other authors have any
conflicts of interests to declare.

Alpha-2-adrenergic receptor agonists for the prevention of delirium and cognitive decline after open heart surgery (ALPHA2PREVENT): protocol for a multicentre randomised controlled trial Neerland, B. E. Busund, R. Haaverstad, R. Helbostad, J. L. Landsverk, S. A. Martinaityte, I. Norum, H. M. Ræder, J. Selbaek, G. Simpson, M. R. Skaar, E. Skjærvold, N. K. Skovlund, E. Slooter, A. J. Svendsen Ø, S. Tønnessen, T. Wahba, A. Zetterberg, H. BMJ Open 2022

Adrenergic alpha-2 Receptor Agonists/therapeutic use
Aged
*Cardiac Surgical Procedures/adverse effects
Clonidine/therapeutic use
*Cognitive Dysfunction/etiology
*Delirium/diagnosis/etiology/prevention & control
*Dexmedetomidine/therapeutic use
Double-Blind Method
*Frailty/complications
Humans
Multicenter Studies as Topic
Randomized Controlled Trials as Topic
adult anaesthesia
cardiac surgery
delirium & cognitive disorders
geriatric medicine

Does modulation of glymphatic system reduce delirium via waste clearance? Naaz, S. Asghar, A. J Anaesthesiol Clin Pharmacol 2022
Delirium in elderly postoperative patients: A prospective cohort study Muzzana, C. Mantovan, F. Huber, M. K. Trevisani, K. Niederbacher, S. Kugler, A. Ausserhofer, D. Nurs Open 2022

delirium
general surgery
nursing assessment
outcome assessment health care
postoperative complications
postoperative delirium

Antimicrobial neurotoxicity: an under-recognised cause of delirium Moynan, D. Maqbool, E. de Barra, E. Acute Med 2022

Aged
Anti-Bacterial Agents/adverse effects
*Brain Diseases/chemically induced/diagnosis/drug therapy
*Delirium/chemically induced/diagnosis
Humans
Male
*Myoclonus/chemically induced/drug therapy

CORR Insights®: Does the SORG Orthopaedic Research Group Hip Fracture Delirium Algorithm Perform Well on an Independent Intercontinental Cohort of Patients With Hip Fractures Who Are 60 Years or Older? Michelson, J. D. Clin Orthop Relat Res 2022
Drug Choice for Hyperactive Delirium in Terminally-Ill Cancer Patients: A Nationwide Survey Matsuda, Y. Morita, T. Oya, K. Tagami, K. Naito, A. S. Kashiwagi, H. Otani, H. J Pain Symptom Manage 2022

cancer
hyperactive delirium
pharmacological treatment
terminal delirium

Implementing delirium screening in the emergency department: a quality improvement project Martin, L. Lyons, M. Patton, A. O. Driscoll M McLoughlin, K. Hannon, E. Deasy, C. BMJ Open Qual 2022

Aged
*Delirium/diagnosis/prevention & control
Emergency Service, Hospital
Humans
Mass Screening
*Quality Improvement
Total Quality Management
Emergency department
Healthcare quality improvement
Quality improvement

Evaluation of the association of anticholinergic burden and delirium in older hospitalised patients - A cohort study comparing 19 anticholinergic burden scales Lisibach, A. Gallucci, G. Benelli, V. Kälin, R. Schulthess, S. Beeler, P. E. Csajka, C. Lutters, M. Br J Clin Pharmacol 2022

Doss
anticholinergic burden
delirium during hospitalisation
older patients

Demand Ischemia as a Predictor of Mortality in Older Patients With Delirium Kumar, M. Patil, S. Godoy, L. D. C. Kuo, C. L. Swede, H. Kuchel, G. A. Chen, K. Front Cardiovasc Med 2022

clinical outcomes
coronary artery disease
delirium
demand ischemia
mortality
commercial or financial relationships that could be construed as a potential
conflict of interest.

Structured Delirium Management in the Hospital Krämer, J. Nolte, K. Zupanc, L. Schnitker, S. Roos, A. Göpel, C. Cid, J. S. Eichler, K. Hooven, T. V. D. Hempel, G. Pavenstädt, H. J. Klaas, C. Gosheger, G. Raschke, M. J. Wiendl, H. Duning, T. Dtsch Arztebl Int 2022

Activities of Daily Living
Aged
*Delirium/diagnosis/prevention & control
Hospitalization
Hospitals
Humans
Length of Stay

A machine learning approach to identifying delirium from electronic health records Kim, J. H. Hua, M. Whittington, R. A. Lee, J. Liu, C. Ta, C. N. Marcantonio, E. R. Goldberg, T. E. Weng, C. JAMIA Open 2022

Confusion Assessment Method for the Intensive Care Unit (CAM-ICU)
delirium
electronic health records
logistic regression
machine learning model