Delirium Bibliography

Delirium Bibliography books graphicWhat is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!

How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.

Reference Information

Title
Preventing Postoperative Delirium After Major Noncardiac Thoracic Surgery-A Randomized Clinical Trial.
Authors
Khan, B. A. Perkins, A. J. Campbell, N. L. Gao, S. Khan, S. H. Wang, S. Fuchita, M. Weber, D. J. Zarzaur, B. L. Boustani, M. A. Kesler, K.
Year
2018
Journal
J Am Geriatr Soc
Abstract

OBJECTIVES: To assess the efficacy of haloperidol in reducing postoperative delirium in individuals undergoing thoracic surgery. DESIGN: Randomized double-blind placebo-controlled trial. SETTING: Surgical intensive care unit (ICU) of tertiary care center. PARTICIPANTS: Individuals undergoing thoracic surgery (N=135). INTERVENTION: Low-dose intravenous haloperidol (0.5 mg three times daily for a total of 11 doses) administered postoperatively. MEASUREMENTS: The primary outcome was delirium incidence during hospitalization. Secondary outcomes were time to delirium, delirium duration, delirium severity, and ICU and hospital length of stay. Delirium was assessed using the Confusion Assessment Method for the ICU and delirium severity using the Delirium Rating Scale-Revised. RESULTS: Sixty-eight participants were randomized to receive haloperidol and 67 placebo. No significant differences were observed between those receiving haloperidol and those receiving placebo in incident delirium (n=15 (22.1%) vs n=19 (28.4%); p = .43), time to delirium (p = .43), delirium duration (median 1 day, interquartile range (IQR) 1-2 days vs median 1 day, IQR 1-2 days; p = .71), delirium severity, ICU length of stay (median 2.2 days, IQR 1-3.3 days vs median 2.3 days, IQR 1-4 days; p = .29), or hospital length of stay (median 10 days, IQR 8-11.5 days vs median 10 days, IQR 8-12 days; p = .41). In the esophagectomy subgroup (n = 84), the haloperidol group was less likely to experience incident delirium (n=10 (23.8%) vs n=17 (40.5%); p = .16). There were no differences in time to delirium (p = .14), delirium duration (median 1 day, IQR 1-2 days vs median 1 day, IQR 1-2 days; p = .71), delirium severity, or hospital length of stay (median 11 days, IQR 10-12 days vs median days 11, IQR 10-15 days; p = .26). ICU length of stay was significantly shorter in the haloperidol group (median 2.8 days, IQR 1.1-3.8 days vs median 3.1 days, IQR 2.1-5.1 days; p = .03). Safety events were comparable between the groups. CONCLUSION: Low-dose postoperative haloperidol did not reduce delirium in individuals undergoing thoracic surgery but may be efficacious in those undergoing esophagectomy. J Am Geriatr Soc 66:2289-2297, 2018.

PMID

30460981

Keywords

Icu
cognition
delirium
esophagectomy
haloperidol

Page(s)
2289-97
Issue
12

Search:
Total Records Found: 6347, showing 100 per page
TitleAuthorsJournalYearKeywords
Evaluating the performance of machine learning methods for risk estimation of delirium in patients hospitalized from the emergency department Mueller, B. Street, W. N. Carnahan, R. M. Lee, S. Acta Psychiatr Scand 2023

delirium, emergency department, risk estimation, health record review, machine learning

Relationship between angiotensin-converting enzyme inhibitors and angiotensin receptor blockers prescribing and delirium in the ICU-A secondary analysis Mulkey, M. A. Khan, S. Perkins, A. Gao, S. Wang, S. Campbell, N. Khan, B. J Am Geriatr Soc 2023

ACE inhibitor, angiotensin receptor blocker, critical care, delirium, intensive care

Bispectral EEG (BSEEG) Algorithm Captures High Mortality Risk Among 1,077 Patients: Its Relationship to Delirium Motor Subtype Nishizawa, Y. Yamanashi, T. Saito, T. Marra, P. Crutchley, K. J. Wahba, N. E. Malicoat, J. Shibata, K. Nishiguchi, T. Lee, S. Cho, H. R. Kanazawa, T. Shinozaki, G. Am J Geriatra Psychiatry 2023

Bseeg, Bispectral electroencephalogram, delirium, mortality, motor subtype

Computable Phenotypes to Characterize Changing Patient Brain Dysfunction in the Intensive Care Unit Ren, Y. Loftus, T. J. Guan, Z. Uddin, R. Shickel, B. Maciel, C. B. Busl, K. Rashidi, P. Bihorac, A. Ozrazgat-Baslanti, T. ArXiv 2023

Acute brain dysfunction, delirium, Intensive Care Unit, automated computable phenotypes, algorithm

Association between obstructive sleep apnea and atrial fibrillation and delirium after cardiac surgery. Sub-analysis of DECADE trial Rivas, E. Shehata, P. Bravo, M. Almonacid-Cardenas, F. Shah, K. Kopac, O. Ruetzler, K. Troianos, C. A. Turan, A. J Clin Anesth 2023

Atrial fibrillation, Cardiac surgery, Delirium, Obstructive sleep apnea, Intensive Care Unit

Spinal Dexamethasone Effect on Cognitive Disorders After Hip Surgery Sakic, L. Tonkovicc, D. Hrgovic, Z. Klasan, A. Med Arch 2023

Humans, Aged, Levobupivacaine, Hydrocortisone, *Cognition Disorders, *Cognitive Dysfunction, Dexamethasone/therapeutic use, delirium, dexamethasone, proximal femoral fracture, spinal anesthesia

Effects of Melatonin Administration on Post-Stroke Delirium in Patients with Intracerebral Hemorrhage Siokas, V. Roesch, S. Stefanou, M. I. Buesink, R. Wilke, V. Sartor-Pfeiffer, J. Adeyemi, K. Poli, S. Dardiotis, E. Ziemann, U. Feil, K. Mengel, A. J Clin Med 2023

intracerebral hemorrhage, melatonin, post-stroke delirium, prospective study, stroke unit

Clinical Risk Group as a predictor of mortality in delirious older adults in the emergency department Soler-Sanchis, A. Martínez-Arnau, F. M. Sánchez-Frutos, J. Pérez-Ros, P. Exp Gerontol 2023

Male, Humans, Aged, Aged, 80 and over, Female, Prospective Studies, *Delirium/diagnosis/complications, Hospitalization, Risk Factors, Emergency Service, Hospital, Chronicity, Delirium, Emergency department, Survival

Plasma biomarkers and delirium in critically ill patients after cardiac surgery: A prospective observational cohort study Su, L. J. Chen, M. J. Yang, R. Zou, H. Chen, T. T. Li, S. L. Guo, Y. Hu, R. F. Heart Lung 2023

Humans, Middle Aged, Prospective Studies, Tumor Necrosis Factor-alpha, Interleukin-6, *Delirium/diagnosis/etiology, Critical Illness, Biomarkers, Intensive Care Units, *Cardiac Surgical Procedures/adverse effects, Cardiac surgery, Delirium, Intensive care unit

Safety of baclofen versus tizanidine for older adults with musculoskeletal pain Su Zhang, V. R. Niu, F. Lee, E. A. DiStasio, C. Broder, B. I. Steinberg, S. G. Hui, R. L. J Am Geriatr Soc 2023

baclofen, delirium, injury, safety, tizanidine

Delirium Risk Score in Elderly Patients with Cervical Spinal Cord Injury and/or Cervical Fracture Tanner, M.Tamai, K. Terai, H. Nakamura, H. Yokogawa, N. Sasagawa, T. Nakashima, H. Segi, N. Ito, S. Funayama, T. Eto, F. Yamaji, A. Watanabe, K. Yamane, J. Takeda, K. Furuya, T. Yunde, A. Nakajima, H. Yamada, T. Hasegawa, T. Terashima, Y. Hirota, R. Suzuk J Clin Med 2023

cervical fracture, cervical spinal cord injury, delirium, elderly, prediction

Persistent delirium in older hospital patients: an updated systematic review and meta-analysis Whitby, J. Nitchingham, A. Caplan, G. Davis, D. Tsui, A. PLoS One 2022

Humans, Aged, *Delirium/etiology, Inpatients, *Cognition Disorders/complications, *Cognitive Dysfunction/complications, Risk Factors, Geriatric Assessment

Delirium in older hospitalized patients-A prospective analysis of the detailed course of delirium in geriatric inpatients Wilke, S. Steiger, E. Bärwolff, T. L. Kleine, J. F. Müller-Werdan, U. Rosada, A. PLoS One 2023

Humans, Aged, *Delirium/etiology, Inpatients, *Cognition Disorders/complications, *Cognitive Dysfunction/complications, Risk Factors, Geriatric Assessment

Anti-inflammatory medication use associated with reduced delirium risk and all-cause mortality: A retrospective cohort study Yamanashi, T. Sullivan, E. J. Comp, K. R. Nishizawa, Y. Akers, C. C. Chang, G. Modukuri, M. Tran, T. Anderson, Z. E. M. Marra, P. S. Crutchley, K. J. Wahba, N. E. Iwata, M. Karam, M. D. Noiseux, N. O. Cho, H. R. Shinozaki, G. J Psychosom Res 2023

Anti-inflammatory medication, Delirium, Glucosamine, Mortality, NSAIDs
LLC and has pending patents as follows: “Non-invasive device for predicting, and screening delirium”, PCT application no. PCT/US2016/064937 and US provisional patent no. 62/263,325, “Prediction of patient outcomes with a novel
electroencephalography device”, US provisional patent no. 62/829,411
“Epigenetic, Biomarker of Delirium Risk” in the PCT Application No. PCT/US19/51276, and in U.S. Provisional Patent No. 62/731,599. All other authors have declared that no conflict of interest exists.

Application of a flexible visitation system in critically ill patients: A randomized clinical trial Yang, H. Y. Feng, F. Yang, W. W. Chen, Y. Sci Prog 2023

Humans, Critical Illness/therapy, *Delirium, Intensive Care Units, Length of Stay, *Cross Infection, ChiCTR2200059093, Flexible visitation system, Trial registration: ChiCTR, delirium, high-quality care

Association between preoperative anxiety and postoperative delirium in older patients: a systematic review and meta-analysis Yang, K. L. Detroyer, E. Van Grootven, B. Tuand, K. Zhao, D. N. Rex, S. Milisen, K. BMC Geriatr 2023

Humans, Aged, 80 and over, *Emergence Delirium, *Delirium/diagnosis/epidemiology/etiology, Prospective Studies, Anxiety/diagnosis, Postoperative, Complications/diagnosis/epidemiology/etiology, Risk Factors
Cognitive dysfunction, Meta-analysis, Older patients, Postoperative delirium, Preoperative anxiety

Ramelteon for delirium prevention in hospitalized patients: An updated meta-analysis and trial sequential analysis of randomized controlled trials Yu, C. L. Carvalho, A. F. Thompson, T. Tsai, T. C. Tseng, P. T. Tu, Y. K. Yang, S. N. Yang, F. C. Chang, C. H. Hsu, C. W. Hsu, T. W. Liang, C. S. J Pineal Res 2023

Humans, Middle Aged, *Delirium/prevention & control/drug therapy/epidemiology, *Melatonin/therapeutic use, Randomized Controlled Trials as Topic, Reproducibility of Results, delirium prevention, hospitalized patients, meta-analysis, ramelteon, trial sequential analysis

A large-scale causal analysis of gut microbiota and delirium: A Mendelian randomization study Yu, H. Wan, X. Yang, M. Xie, J. Xu, K. Wang, J. Wang, G. Xu, P. J Affect Disord 2023

Humans, *Gastrointestinal Microbiome/genetics, Mendelian Randomization, Analysis, Causality, *Delirium/epidemiology/genetics, Genome-Wide Association Study, Causal correlation, Delirium, Gut microbiota, Large scale analysis, Mendelian randomization

Effectiveness of dexmedetomidine on postoperative cognitive dysfunction in elderly patients with fracture: A systematic review Zeng, T., Lv, J., Cui, Y., Li, X., F. Zhang, Q. Medicine (Baltimore) 2023

Aged, Humans, Cognition, *Cognitive Dysfunction/etiology,, *Delirium/epidemiology/etiology, *Dexmedetomidine/adverse effects, *Postoperative Cognitive Complications, Postoperative, Complications/epidemiology, Randomized Controlled Trials as Topic

Pharmacologic Interventions to Prevent Delirium in Trauma Patients: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials Zitikyte, G. Roy, D. C. Tran, A. Fernando, S. M. Rosenberg, E. Kanji, S. Engels, P. T. Wells, G. A. & Vaillancourt, C. Crit Care Explor 2023

critical care, delirium, dexmedetomidine, propofol, systematic review, trauma, interest

A novel predictive model for postoperative delirium using multiple geriatric screening factors Yajima, S. Nakanishi, Y. Sugimoto, M. Kobayashi, S. Kudo, M. Yasujima, R. Hirose, K. Sekiya, K. Umino, Y. Okubo, N. Kataoka, M. Gotohda, N. Masuda, H. J Surg Oncol 2023

Mini-Cog
elderly patients
postoperative delirium
risk factors
urological surgery

The Effect of Consultation-Liaison Psychiatry on Postoperative Delirium in Elderly Hip Fracture Patients in the General Hospital Xie, Q. Liu, X. B. Jing, G. W. Jiang, X. Liu, H. Zhong, B. L. Li, Y. Orthop Surg 2023

Humans
Aged
*Emergence Delirium
Prospective Studies
Hospitals, General
*Psychiatry
*Hip Fractures/complications/surgery
Referral and Consultation
confusion
delirium
hip fracture
psychiatry

Quantitative EEG signatures of delirium and coma in mechanically ventilated ICU patients Williams Roberson, S. Azeez, N. A. Fulton, J. N. Zhang, K. C. Lee, A. X. T. Ye, F. Pandharipande, P. Brummel, N. E. Patel, M. B. Ely, E. W. Clin Neurophysiol 2023

Humans
*Coma/diagnosis
*Delirium/diagnosis
Intensive Care Units
Respiration, Artificial
Electroencephalography
Critical care
Delirium
Encephalopathy
qEEG

Delirium in trauma ICUs: a review of incidence, risk factors, outcomes, and management Williams, E. C. Estime, S. Kuza, C. M. Curr Opin Anaesthesiol 2023
Cerebrospinal fluid quinolinic acid is strongly associated with delirium and mortality in hip-fracture patients Watne, L. O. Pollmann, C. T. Neerland, B. E. Quist-Paulsen, E. Halaas, N. B. Idland, A. V. Hassel, B. Henjum, K. Knapskog, A. B. Frihagen, F. Raeder, J. Godø, A. Ueland, P. M. McCann, A. Figved, W. Selbæk, G. Zetterberg, H. Fang, E. F. Myrstad, M. Giil, J Clin Invest 2023

Humans
Quinolinic Acid/cerebrospinal fluid
Acute Disease
*Hip Fractures/cerebrospinal fluid/complications/psychology
Kynurenine/metabolism
*Delirium/etiology/cerebrospinal fluid
Inflammation/complications
Dementia
Inflammation
Metabolism
Neurological disorders
Psychiatric diseases

Effect of perioperative benzodiazepine use on intraoperative awareness and postoperative delirium: a systematic review and meta-analysis of randomised controlled trials and observational studies Wang, E. Belley-Côté, E. P. Young, J. He, H. Saud, H. D'Aragon, F. Um, K. Alhazzani, W. Piticaru, J. Hedden, M. Whitlock, R. Mazer, C. D. Kashani, H. H. Zhang, S. Y. Lucas, A. Timmerman, N. Nishi, C. Jain, D. Kugler, A. Beaver, C. Kloppenburg, S. Schulm Br J Anaesth 2023

benzodiazepines
intraoperative awareness
meta-analysis
perioperative medicine
postoperative delirium
systematic review

Sustained adherence to a delirium guideline five years after implementation in an intensive care setting: A retrospective cohort study van Bochove-Waardenburg, M. van der Jagt, M. de Man-van Ginkel, J. Ista, E. Intensive Crit Care Nurs 2023

Adherence
Critical care
Delirium
Guideline
Implementation
Intensive care unit

A survey of current practices in sedation, analgesia, withdrawal, and delirium management in paediatric cardiac ICUs Valentine, K. Cisco, M. J. Lasa, J. J. Achuff, B. J. Kudchadkar, S. R. Staveski, S. L. Cardiol Young 2023

Delirium
ICUs
analgesia
drug withdrawal
paediatric
sedation

Understanding the association between admission source and in-hospital delirium: A cross-sectional study Thomas, M. K. Heincelman, M. E. Zhang, J. Marsden, J. Dulin, J. Robbins, P. Hunt, K. Mauldin, P. Moran, W. P. Kalivas, B. J Investig Med 2023

Adult
Humans
Cross-Sectional Studies
*Hospitalization
Hospitals
Patient Transfer
Emergency Service, Hospital
*Delirium/epidemiology/diagnosis
Length of Stay
Cognition
Inpatients

Sevoflurane dose and postoperative delirium: a prospective cohort analysis Taylor, J. Payne, T. Casey, C. Kunkel, D. Parker, M. Rivera, C. Zetterberg, H. Blennow, K. Pearce, R. A. Lennertz, R. C. McCulloch, T. Gaskell, A. Sanders, R. D. Br J Anaesth 2023

Humans
Sevoflurane/adverse effects
*Emergence Delirium/epidemiology
*Anesthetics, Inhalation/adverse effects
Prospective Studies
Cohort Studies
anaesthesia
biomarker
cognitive dysfunction
delirium
dose dependency
postoperative
sevoflurane
surgery

Efficacy of transcranial direct current stimulation on postoperative delirium in elderly patients undergoing lower limb major arthroplasty: A randomized controlled trial Tao, M. Zhang, S. Han, Y. Li, C. Wei, Q. Chen, D. Zhao, Q. Yang, J. Liu, R. Fang, J. Li, X. Zhang, H. Liu, H. Cao, J. L. Brain Stimul 2023

Lower limb major arthroplasty
Postoperative delirium
Postoperative pain
Total hip arthroplasty
Total knee arthroplasty
Transcranial direct current stimulation

Medical and economic burden of delirium on hospitalization outcomes of acute respiratory failure: A retrospective national cohort Taha, A. Xu, H. Ahmed, R. Karim, A. Meunier, J. Paul, A. Jawad, A. Patel, M. L. Medicine (Baltimore) 2023

Humans
Retrospective Studies
*Financial Stress
Hospitalization
Length of Stay
Intensive Care Units
*Respiratory Insufficiency/therapy

Poor prognostic impact of delirium: especially on mortality and institutionalisation Tachibana, M. Inada, T. Psychogeriatrics 2023

Humans
Aged
*Delirium/diagnosis/etiology
Prognosis
*covid-19
Institutionalization
Covid-19
age
delirium

Processed electroencephalography-guided general anaesthesia to reduce postoperative delirium: a systematic review and meta-analysis Sumner, M. Deng, C. Evered, L. Frampton, C. Leslie, K. Short, T. Campbell, D. Br J Anaesth 2023

Humans
Aged
*Emergence Delirium/epidemiology/prevention & control
Anesthesia, General/adverse effects
Postoperative Complications/prevention & control
Electroencephalography
Eeg
bispectral index
postoperative delirium
postoperative neurocognitive disorders
processed EEG
processed electroencephalography

Expanding options to include language barriers for predicting postoperative delirium in geriatric patients Streetman, D. Hagley, A. Shalom, M. Gendreau, J. L. J Am Geriatr Soc 2023

Humans
Aged
*Emergence Delirium
*Delirium/diagnosis
Length of Stay
Communication Barriers
Postoperative Complications/diagnosis
Geriatric Assessment
Risk Factors

Comparison of logistic regression and machine learning methods for predicting postoperative delirium in elderly patients: A retrospective study Song, Y. X. Yang, X. D. Luo, Y. G. Ouyang, C. L. Yu, Y. Ma, Y. L. Li, H. Lou, J. S. Liu, Y. H. Chen, Y. Q. Cao, J. B. Mi, W. D. CNS Neurosci Ther 2023

Humans
Aged
Retrospective Studies
*Emergence Delirium
Logistic Models
ROC Curve
Machine Learning
delirium
nomograms
risk assessment

Effects of anti-ulcer drugs on delirium in trauma patients Sogawa, R. Matsuoka, A. Murakawa-Hirachi, T. Kikkawa, N. Kamo, M. Tobita, S. Shinada, K. Mizoguchi, Y. Monji, A. Sakamoto, Y. Shimanoe, C. Gen Hosp Psychiatry 2023

Humans
*Anti-Ulcer Agents
Histamine H2 Antagonists/adverse effects
Proton Pump Inhibitors/adverse effects
Hospitalization
*Delirium/epidemiology/chemically induced
Delirium
Histamine-2 receptor antagonist
Proton pump inhibitor

Delirium superimposed on dementia in post-acute care: Nurse documentation of symptoms and interventions Sillner, A. Y. Berish, D. Mailhot, T. Sweeder, L. Fick, D. M. Kolanowski, A. M. Geriatr Nurs 2023

Humans
Aged
*Dementia/complications
*Delirium/diagnosis
Subacute Care
*Nursing Care
Documentation
Delirium
Delirium Superimposed on Dementia
Dementia
Nurse Documentation
Nurse Intervention

Postoperative Delirium after Dexmedetomidine versus Propofol Sedation in Healthy Older Adults Undergoing Orthopedic Lower Limb Surgery with Spinal Anesthesia: A Randomized Controlled Trial Shin, H. J. Woo Nam, S. Kim, H. Yim, S. Han, S. H. Hwang, J. W. Do, S. H. Na, H. S. Anesthesiology 2023

Humans
Aged
*Propofol/adverse effects
*Dexmedetomidine/adverse effects
*Emergence Delirium/chemically induced
*Anesthesia, Spinal/adverse effects
*Delirium/chemically induced/epidemiology
Hypnotics and Sedatives/adverse effects
Lower Extremity/surgery

Preoperative characterization of baseline EEG recordings for risk stratification of post-anesthesia care unit delirium Schüßler, J. Ostertag, J. Georgii, M. T. Fleischmann, A. Schneider, G. Pilge, S. Kreuzer, M. J Clin Anesth 2023

Anesthesia
Baseline EEG recording
Cognitive assessment
Neuromonitoring
Pacu-d
Perioperative medicine

Certified Nursing Assistants' Perspectives on Delirium Care Sabbe, K. Aerts, N. van der Mast, R. Van Rompaey, B. J Gerontol Nurs 2023

Humans
Nursing Homes
Emotions
Qualitative Research
*Nursing Assistants/psychology
*Delirium

Neurophysiologic predictors of individual risk for post-operative delirium after elective surgery Ross, J. M. Santarnecchi, E. Lian, S. J. Fong, T. G. Touroutoglou, A. Cavallari, M. Travison, T. G. Marcantonio, E. R. Libermann, T. A. Schmitt, E. M. Inouye, S. K. Shafi, M. M. Pascual-Leone, A. J Am Geriatr Soc 2023

Humans
Aged
Aged, 80 and over
*Emergence Delirium
*Delirium/diagnosis/etiology
Pilot Projects
*Cognitive Dysfunction/diagnosis/etiology
Elective Surgical Procedures/adverse effects
Electroencephalography
Transcranial Magnetic Stimulation
connectivity
delirium
plasticity
transcranial magnetic stimulation

Nighttime dexmedetomidine for delirium prevention in non-mechanically ventilated patients after cardiac surgery (MINDDS): A single-centre, parallel-arm, randomised, placebo-controlled superiority trial Qu, J. Z. Mueller, A. McKay, T. B. Westover, M. B. Shelton, K. T. Shaefi, S. D'Alessandro, D. A. Berra, L. Brown, E. N. Houle, T. T. Akeju, O. EClinicalMedicine 2023

Cardiac surgery
Delirium
Dexmedetomidine
Neurocognition
Sleep

Effect of seasons on delirium in postoperative critically ill patients: a retrospective analysis Qiu, Y. Rivas, E. Tanios, M. Sreedharan, R. Mao, G. Ince, I. Salih, A. Saab, R. Devarajan, J. Ruetzler, K. Turan, A. Braz J Anesthesiol 2023

Adult
Humans
Retrospective Studies
Seasons
*Delirium/epidemiology/etiology
*Emergence Delirium
Critical Illness
Intensive Care Units
Postoperative delirium
Seasonal
Surgical Intensive care unit

Transcutaneous electrical acupoint stimulation combined with an integrated perioperative nursing program prevents subsyndromal delirium in older patients after joint replacement Qian, J. He, M. Zhan, X. Ren, L. Sun, Q. Geriatr Nurs 2023

Humans
Aged
Acupuncture Points
Perioperative Nursing
*Arthroplasty, Replacement
*Delirium/prevention & control
Delirium
Joint replacement
Nursing
Older patients
Subsyndromal delirium
Transcutaneous electrical acupoint stimulation

Web-Based Delirium Prevention Application for Long-Term Care Facilities Park, M. Moon, K. J. J Am Med Dir Assoc 2023

Delirium
long-term care
machine learning
predictive model
prevention

The effect of all-cause hospitalization on cognitive decline in older adults: a longitudinal study using databases of the National Health Insurance Service and the memory clinics of a self-run hospital Park, D. Kim, H. S. Kim, J. H. BMC Geriatr 2023

Humans
Aged
Longitudinal Studies
Activities of Daily Living
Retrospective Studies
*Cognitive Dysfunction/diagnosis/epidemiology/therapy
National Health Programs
*Delirium
Cognitive dysfunction
Hospitalization

Investigating nurses' knowledge and attitudes about delirium in older persons: a cross-sectional study Papaioannou, M. Papastavrou, E. Kouta, C. Tsangari, H. Merkouris, A. BMC Nurs 2023

Acute confusion
Attitudes
Delirium
Knowledge
Nurse

Risk factors and consequences of post-esophagectomy delirium: a systematic review and meta-analysis Papaconstantinou, D. Frountzas, M. Ruurda, J. P. Mantziari, S. Tsilimigras, D. I. Koliakos, N. Tsivgoulis, G. Schizas, D. Dis Esophagus 2023

anastomotic leakage
complications
esophageal cancer surgery
meta-analysis

Natural Language Processing CAM Algorithm Improves Delirium Detection Compared With Conventional Methods Pagali, S. R. Kumar, R. Fu, S. Sohn, S. Yousufuddin, M. Am J Med Qual 2023

Humans
*Delirium/diagnosis/epidemiology
Retrospective Studies
Artificial Intelligence
Natural Language Processing
*COVID-19/diagnosis
Algorithms

Predisposing and Precipitating Factors Associated With Delirium: A Systematic Review Ormseth, C. H. LaHue, S. C. Oldham, M. A. Josephson, S. A. Whitaker, E. Douglas, V. C. JAMA Netw Open 2023

Adult
Humans
Male
Female
Disease Susceptibility
*Delirium/epidemiology/etiology
Precipitating Factors
Prospective Studies
Case-Control Studies

Prevalence of pre-operative undiagnosed cognitive impairment and its association with handgrip strength, oral hygiene, and nutritional status in older elective surgical patients in Japan Nakatani, S. Ida, M. Uyama, K. Kinugasa, Y. Kawaguchi, M. J Anesth 2023

Humans
Aged
Nutritional Status
Hand Strength
*Frailty
Prevalence
Japan
Oral Hygiene
*Cognitive Dysfunction
Cognitive dysfunction
Delirium
Oral health

Preoperative anxiety as an independent predictor of postoperative delirium in older patients undergoing elective surgery for lumbar disc herniation Mou, Q. Gao, M. Liu, X. Wei, C. Lan, G. Zhao, X. Shan, Y. Wu, C. Aging Clin Exp Res 2023

Humans
Aged
*Intervertebral Disc Displacement/complications/surgery/epidemiology
*Emergence Delirium
Lumbar Vertebrae/surgery
Anxiety
Postoperative Complications/epidemiology/etiology
Risk Factors
Elective surgery
Lumbar disc herniation
Older
Postoperative delirium

Tracheostomy Is Associated With a Decrease in Delirium and Sedation for Intubated COVID-19 Patients Morton, C. Pisani, M. Doyle, M. Puchalski, J J Bronchology Interv Pulmonol 2023

Humans
Retrospective Studies
Tracheostomy
Respiration, Artificial
*Delirium/epidemiology
*covid-19
Hypnotics and Sedatives/therapeutic use
Benzodiazepines/therapeutic use
Intensive Care Units
Analgesics, Opioid

Characterising the prodromal phase in dementia with Lewy bodies Mellergaard, C. Waldemar, G. Vogel, A. Frederiksen, K. S. Parkinsonism Relat Disord 2023

Humans
*Lewy Body Disease/complications/diagnosis
Retrospective Studies
*Alzheimer Disease
*Parkinson Disease
*Cognitive Dysfunction/etiology
Prodromal Symptoms
*Delirium

Mobilisation in the EveNing to TreAt deLirium (MENTAL): protocol for a mixed-methods feasibility randomised controlled trial McWilliams, D. King, E. Nydahl, P. Darbyshire, J. L. Gallie, L. Barghouthy, D. Bassford, C. Gustafson, O. BMJ Open 2023

Humans
Feasibility Studies
*Delirium/therapy/etiology
Physical Therapy Modalities
Intensive Care Units
Critical Care/methods
Randomized Controlled Trials as Topic
Delirium & cognitive disorders
Intensive & critical care
Rehabilitation medicine
Sleep medicine

Could a Tailored Exercise Intervention for Hospitalised Older Adults Have a Role in the Resolution of Delirium? Secondary Analysis of a Randomised Clinical Trial Martinez Velilla, N. Lozano-Vicario, L. Sáez de Asteasu, M. L. Zambom-Ferraresi, F. Galbete, A. Sanchez-Latorre, M. Izquierdo, M. J Frailty Aging 2023

Humans
Aged
*Hospitalization
Exercise
Exercise Therapy
*Delirium/prevention & control
Delirium
geriatric
hospital

Dexmedetomidine for the prevention of delirium in adults admitted to the intensive care unit or postoperative care unit: a systematic review of randomised clinical trials with meta-analysis and Trial Sequential Analysis Maagaard, M. Barbateskovic, M. Andersen-Ranberg, N. C. Kronborg, J. R. Chen, Y. X. Xi, H. H. Perner, A. Wetterslev, J. Acta Anaesthesiol Scand 2023

Dexmedetomidine
delirium
intensive care unit
meta-analysis
postoperative
systematic review

High ASA Physical Status and Low Serum Uric Acid to Creatinine Ratio are Independent Risk Factors for Postoperative Delirium Among Older Adults Undergoing Urinary Calculi Surgery Liu, J. Li, J. Gao, D. Wang, J. Liu, M. Yu, D. Clin Interv Aging 2023

Humans
Aged
*Emergence Delirium
Uric Acid
*Delirium/epidemiology/etiology/prevention & control
Creatinine
Retrospective Studies
Postoperative Complications/etiology
Risk Factors
*Urinary Calculi/surgery/complications
ASA physical status
older adults
postoperative delirium
risk stratification score
serum uric acid to creatinine ratio
urinary calculi surgery

Dexmedetomidine administration during brain tumour resection for prevention of postoperative delirium: a randomised trial Li, S. Li, R. Li, M. Cui, Q. Zhang, X. Ma, T. Wang, D. Zeng, M. Li, H. Bao, Z. Peng, Y. Sessler, D. I. Br J Anaesth 2023

Humans
*Emergence Delirium
*Dexmedetomidine/therapeutic use
*Delirium/etiology
Pain, Postoperative/prevention & control/drug therapy
*Brain Neoplasms/surgery
Double-Blind Method
brain tumour resection
confusion assessment method
delirium
dexmedetomidine
randomised trial

Effect of a repeated verbal reminder of orientation on emergence agitation after general anaesthesia for minimally invasive abdominal surgery: a randomised controlled trial Lee, S. Sohn, J. Y. Hwang, I. E. Lee, H. J. Yoon, S. Bahk, J. H. Kim, B. R. Br J Anaesth 2023

delirium
emergence agitation
general anaesthesia
recovery from anaesthesia
safety

A pilot study testing the iOS UB-CAM delirium app Kuzmik, A. Hannan, J. Boltz, M. Shrestha, P. Husser, E. K. Fick, D. M. Marcantonio, E. R. J Am Geriatr Soc 2023
Use of a nursing-led geriatrics consult service to deliver age-friendly care Kuntz, A. A. Stumm, E. K. Anderson, T. C. Ibarra, S. J. Markart, M. R. Haske-Palomino, M. Geriatr Nurs 2023

Acute care
Advance care planning
Age friendly care
Delirium
Geriatrics
Quality improvement

Relationship between body mass index and risk of delirium in an intensive care unit Ko, Y. Kim, H. E. Park, J. Y. Kim, J. J. Cho, J. Oh, J. Arch Gerontol Geriatr 2023

Body mass index
Delirium
Encephalopathy
Intensive care unit
Obesity
Overweight
Underweight

Occurrence of Postoperative Delirium and the Use of Different Assessment Tools Kirfel, A. Jossen, D. Menzenbach, J. Mayr, A. Wittmann, M. Geriatrics (Basel) 2023

comparison of postoperative delirium assessments
delirium occurrence postoperatively
postoperative delirium

Association of C-reactive protein to albumin ratio with postoperative delirium and mortality in elderly patients undergoing hip fracture surgery: A retrospective cohort study in a single large center Kim, H. J. Lee, S. Kim, S. H. Lee, S. Sim, J. H. Ro, Y. J. Exp Gerontol 2023

Aged
Humans
Albumins
C-Reactive Protein
*Emergence Delirium/complications
*Hip Fractures/complications
Postoperative Complications/epidemiology/etiology
Retrospective Studies
Risk Factors
Albumin
Delirium
Hip fracture
Prognosis
declare.

Relationship Among Clinically Obtained Biomarkers of Inflammation, Hypercoagulability, and Macrophage Activation, and Delirium in Critically Ill Patients With COVID-19 Khan, S. H. Perkins, A. J. Chi, R. Seyffert, S. Conrad, P. Lindroth, H. Wang, S. Mulkey, M. Gao, S. Khan, B. Crit Care Explor 2023

Covid-19
biomarkers
coma
critical care
delirium
delirium severity

Lower Preoperative Verbal Memory Performance Is Associated with Delirium after Coronary Artery Bypass Graft Surgery: A Prospective Cohort Study Kaźmierski, J. Miler, P. Pawlak, A. Woźniak, J. Frankowska, E. Nowakowska, K. Kuchta, K. Pazdrak, M. Woźniak, K. Magierski, R. Krejca, M. Wilczyński, M. Arch Clin Neuropsychol 2023

Humans
Female
Middle Aged
Aged
Prospective Studies
*Delirium/diagnosis/etiology/psychology
*Emergence Delirium/complications
Neuropsychological Tests
Postoperative Complications/etiology/diagnosis/psychology
Coronary Artery Bypass/adverse effects
Cognition
Risk Factors
Cardiovascular disease
Cognitive impairment
Coronary artery bypass grafting
Delirium
Verbal memory

Postoperative Delirium After Intracranial Surgery: A Retrospective Cohort Study Kappen, P. R. Kappen, H. J. Dirven, C. M. F. Klimek, M. Jeekel, J. Andrinopoulou, E. R. Osse, R. J. Vincent, Ajpe World Neurosurg 2023

Health outcomes
Impact
Neurosurgery
Pod
Prediction model
Risk factors

Actigraphy-based sleep and activity measurements in intensive care unit patients randomized to ramelteon or placebo for delirium prevention Jaiswal, S. J. Bagsic, S. R. S. Takata, E. Kamdar, B. B. Ancoli-Israel, S. Owens, R. L. Sci Rep 2023

Humans
*Actigraphy
Sleep
Circadian Rhythm
*Delirium/drug therapy/prevention & control
Intensive Care Units

Visualizing how to use antipsychotics for agitated delirium in the last days of life Imai, K. Morita, T. Mori, M. Kikuchi, D. Yokomichi, N. Miwa, S. Okamoto, S. I. Yamauchi, T. Naito, A. S. D. Matsuda, Y. Maeda, I. Sugano, K. Inanga, M. Inoue, S. Satomi, E. J Pain Symptom Manage 2023

antipsychotics
chlorpromazine
haloperidol
levomepromazine
terminal agitated delirium
treatment algorithm

Is postoperative delirium an independent risk factor for poorer quality of life with long-term cognitive and functional decline after cardiac surgery? Hu, F. H. Chen, H. L. J Clin Anesth 2023
Diagnostic accuracy of the 4AT for delirium: A systematic review and meta-analysis Hou, L. Zhang, Q. Cao, L. Chen, M. Wang, Q. Li, Y. Li, S. Ge, L. Yang, K. Asian J Psychiatr 2023

Humans
Aged
Sensitivity and Specificity
*Delirium/diagnosis
4at
Delirium
Diagnostic
Geriatrics
Meta-analysis

Several reasons why ketamine as a neuroplastic agent may have failed to prevent postoperative delirium: Implications for future protocols Horacek, J. Janda, R. Görnerova, N. Jajcay, L. Andrashko, V. Neurosci Lett 2023

Anesthesia
Benzodiazepines
Ketamine
Neuroplastic
Neuroprotective
Pharmacological interaction
Postoperative delirium

Evaluation of Education and Patient Screening for Delirium Among Patients With Stroke: Knowledge, Confidence, and Patient Outcomes Herrera, E. Rutherford, W. Plume, T. Fields, W. Mollon, D. J Contin Educ Nurs 2023

Humans
Intensive Care Units
*Delirium/diagnosis
Patients
*Stroke/complications/diagnosis
Educational Status
*Cross Infection

The kynurenine pathway implicated in patient delirium: possible indications for indoleamine 2,3 dioxygenase inhibitors Heimberger, A. B. Lukas, R. V. J Clin Invest 2023

Humans
*Delirium
*Indoleamine-Pyrrole 2,3,-Dioxygenase/antagonists & inhibitors
*Kynurenine/metabolism
Tryptophan/metabolism

Family presence during critical illness may protect against delirium Hart, J. L. Evid Based Nurs 2023

Critical Care Nursing
Ethics
Patient-Centered Care

Risk factors for delirium in advanced cancer patients: A systematic review and meta-analysis Guo, Y. Mu, Y. Wu, T. Xu, Q. Lin, X. Eur J Oncol Nurs 2023

Advanced cancer
Delirium
Meta-analysis
Risk factors
Systematic review
interests.

Prevention of physical restraints in the acute care setting (PROTECT): study protocol for a cluster-randomised controlled pilot study Gottschalk, S. Meyer, G. Haastert, B. Abraham, J. BMJ Open 2023

Humans
Pilot Projects
*Restraint, Physical
Focus Groups
Germany
Randomized Controlled Trials as Topic
Delirium & cognitive disorders
Dementia
Geriatric medicine

Association Between the FRAIL Scale and Postoperative Complications in Older Surgical Patients: A Systematic Review and Meta-Analysis Gong, S. Qian, D. Riazi, S. Chung, F. Englesakis, M. Li, Q. Huszti, E. Wong, J. Anesth Analg 2023

Humans
Aged
*Frailty/complications/diagnosis
Frail Elderly
*Emergence Delirium
Geriatric Assessment
Postoperative Complications/diagnosis/etiology

Phenobarbital to manage severe gamma-hydroxybutyrate withdrawal: A case series Freeman, G. Siefried, K. J. Roberts, D. M. Rodgers, C. Nic Ionmhain, U. Ramanathan, J. Ezard, N. Brett, J. Drug Alcohol Rev 2023

Humans
*Sodium Oxybate/therapeutic use
Prospective Studies
Phenobarbital/therapeutic use
*Substance Withdrawal Syndrome/drug therapy
Benzodiazepines/therapeutic use
*Delirium/chemically induced/drug therapy
barbiturates
benzodiazepine resistance
gamma-hydroxybutyrate withdrawal
phenobarbital

The Modified and Extended Hospital Elder Life Program: A remote model of care to expand delirium prevention Fong, T. G. Albaum, J. A. Anderson, M. L. Cohen, S. G. Johnson, S. Supiano, M. A. Vlisides, P. E. Wade, H. L. Weinberg, L. Wierman, H. R. Zachary, W. Inouye, S. K. J Am Geriatr Soc 2023

Covid-19
delirium
delirium prevention
multicomponent

Contribution of intraoperative electroencephalogram suppression to frailty-associated postoperative delirium: mediation analysis of a prospective surgical cohor Fang, P. P. Shang, Z. X. Xu, J. Hu, J. Zhang, S. C. Fan, Y. G. Lu, Y. Liu, X. S. Maze, M. Br J Anaesth 2023

Humans
Aged
*Emergence Delirium
*Frailty/diagnosis/complications
Prospective Studies
*Delirium/etiology
Mediation Analysis
Risk Factors
Electroencephalography
Postoperative Complications/diagnosis
electroencephalogram suppression
frailty
older patients
postoperative delirium

Nighttime dexmedetomidine for postoperative delirium prevention: a promising step forward Devlin, J. W. Hughes, C. G. EClinicalMedicine 2023

CI, Confidence Intervals
ICU, Intensive Care Unit
NCD, Neurocognitive Disorder
OR, Odds Ratio
kg, kilograms
ug, micrograms

Intraoperative infusion of dexmedetomidine for prevention of postoperative delirium in elderly patients undergoing craniotomy: a protocol of randomised clinical trial Cui, Q. Ma, T. Liu, M. Shen, Z. Li, S. Zeng, M. Liu, X. Zhang, L. Peng, Y. BMJ Open 2023

Humans
Aged
*Dexmedetomidine/therapeutic use
*Emergence Delirium/chemically induced
Double-Blind Method
Intensive Care Units
Craniotomy
Randomized Controlled Trials as Topic
Clinical trials
Geriatric medicine
Neurological oncology
Neurosurgery

Evaluating Implementation and Outcomes of a Person-Centered Care Model for People with Dementia in the Rehabilitation In-Patient Setting: Project Protocol Chenoweth, L. Williams, A. McGuire, J. Reyes, P. Maiden, G. Brodaty, H. Liu, Z. Cook, J. McCade, D. Taylor-Rubin, C. Freeman, M. Burley, C. J Alzheimers Dis 2023

Delirium
dementia
health personnel
hospitals
patient-centered care
quality of healthcare

Statin Use and Delirium Risk: An Updated Systematic Review and Meta-Analysis Chang, Y. H. Wang, J. Y. Peng, T. R. Lian, J. H. Lee, M. C. Chen, H. M. Am J Ther 2023
Utility of head computed tomography for older adults with suspected delirium in the emergency department: A retrospective observational study Butcher, J. D. Smith, M. C. Roberts, L. Ellis, B. Acad Emerg Med 2023

Humans
Aged
Retrospective Studies
*Emergency Service, Hospital
*Delirium/diagnostic imaging
Tomography, X-Ray Computed/methods
Tomography
Glasgow Coma Scale
Ct
computed tomography
delirium
emergency medicine
geriatrics

Hypomagnesemia and incident delirium in hospitalized older persons Boccardi, V. Ercolani, S. Serra, R. Bubba, V. Piccolo, A. Scamosci, M. Villa, A. Ruggiero, C. Mecocci, P. Aging Clin Exp Res 2023

Delirium
Geriatrics
Magnesium
Nutrition
Older

Delirium secondary to anticholinergics Bellizzi, A. Mercieca, E. Dimech, C. BMJ Case Rep 2023

Male
Humans
Cholinergic Antagonists/adverse effects
Procyclidine/therapeutic use
*Antipsychotic Agents/adverse effects
Hallucinations/chemically induced/drug therapy
*Delirium/chemically induced
delirium
drugs: psychiatry
psychiatry

The Effectiveness of Dexmedetomidine as a Prophylactic Treatment for Emergence Delirium Among Combat Veterans With High Anxiety: A Randomized Placebo-Controlled Trial Bartoszek, M. McGuire, J. M. Wilson, J. T. Sorensen, J. S. Vice, T. F. R. Hudson, A. J. Mil Med 2023

Humans
Child
*Emergence Delirium/drug therapy/prevention & control
*Veterans
*Dexmedetomidine/pharmacology/therapeutic use
*Delirium
Prospective Studies
Anesthesia, General
*Anesthetics
Double-Blind Method
Anxiety/drug therapy

Implementing an intervention to enhance care delivery and consistency for people with hip fracture and cognitive impairment in acute hospital wards: a mixed methods process evaluation of a randomised controlled feasibility trial (PERFECTED) Backhouse, T. Fox, C. Hammond, S. P. Poland, F. McDermott-Thompson, V. Penhale, B. Cross, J. L. BMJ Open 2023

Humans
Feasibility Studies
*Hip Fractures/therapy
Hospitalization
Hospitals
*Cognitive Dysfunction/therapy
Delirium & cognitive disorders
Dementia
Orthopaedic & trauma surgery

Association of delirium with increased short-term mortality among older emergency department patients: A cohort study Arneson, M. L. Oliveira, J. E. Silva L. Stanich, J. A. Jeffery, M. M. Lindroth, H. L. Ginsburg, A. D. Bower, S. M. Mullan, A. F. Bellolio, F. Am J Emerg Med 2023

Delirium
Elderly
Emergency department
Mortality

Catatonia and Delirium: Assessment of Comorbidity, Prevalence, and Therapeutic Response in Medically Ill Inpatients From a University Hospital Appiani, F. J. Duarte, J. M. Sauré, M. Rodríguez Cairoli, F. Momeño, V. Yaryour, C. Sarotto, L. J Clin Psychopharmacol 2023

Humans
*Catatonia/diagnosis/drug therapy/epidemiology
Lorazepam/therapeutic use
Inpatients
Prevalence
Comorbidity
Hospitals
*Delirium/diagnosis/drug therapy/epidemiology

The Relationship between Delirium and Statin Use According to Disease Severity in Patients in the Intensive Care Unit An, J. Y. Park, J. Y. Cho, J. Kim, H. E. Park, J. Oh, J. Clin Psychopharmacol Neurosci 2023

APACHE II score
Delirium
Disease severity
Intensive care unit
Neuroinflammation
Statin

Delirium and Healthcare Utilization in Patients Undergoing Hematopoietic Stem Cell Transplantation Amonoo, H. L. Markovitz, N. H. Johnson, P. C. Kwok, A. Dale, C. Deary, E. C. Daskalakis, E. Choe, J. J. Yamin, N. Gothoskar, M. Cronin, K. G. Fernandez-Robles, C. Pirl, W. F. Chen, Y. B. Cutler, C. Lindvall, C. El-Jawahri, A. Transplant Cell Ther 2023
Comparison of Prognostic Accuracy of 3 Delirium Prediction Models Amerongen, H. V. N. Stapel, S. Spijkstra, J. J. Ouweneel, D. Schenk, J. Am J Crit Care 2023

Adult
Humans
Prognosis
*Delirium/diagnosis
Retrospective Studies
Apache
Intensive Care Units

Melatonin or Ramelteon for Delirium Prevention in the Intensive Care Unit: A Systematic Review and Meta-Analysis of Randomized Controlled Trials Aiello, G. Cuocina, M. La Via, L. Messina, S. Attaguile, G. A. Cantarella, G. Sanfilippo, F. Bernardini, R. J Clin Med 2023

agonist
critical care
length of stay
mechanical ventilation
mortality

The Role of Insulin-Like Growth Factor 1 in Delirium: A Systematic Review and Meta-Analysis Adamis, D. Eikelenboom, P. Dement Geriatr Cogn Disord 2023

Biomarkers
Delirium
Insulin-like growth factor 1
Meta-analysis
Pathophysiology
Systematic review

Influence of dosing pattern of antipsychotics on treatment outcome of delirium in patients with advanced cancer Abe, A. Fujisawa, D. Miyajima, K. Takeuchi, E. Takeuchi, M. Mimura, M. Imai, K. Uemura, K. Watanabe, H. Matsuo, N. Matsuda, Y. Maeda, I. Ogawa, A. Yoshiuchi, K. Iwase, S. Jpn J Clin Oncol 2023

antipsychotics
cancer
delirium
palliative care
pharmacotherapy