Delirium Bibliography

Delirium Bibliography books graphicWhat is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!

How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.

Reference Information

Factors associated with delirium in a real-world acute-care setting: analysis considering the interdependence of clinical variables with the frailty syndrome
Ticinesi, A. Parise, A. Delmonte, D. Coppi, C. Prati, B. Cerundolo, N. Guerra, A. Nouvenne, A. Meschi, T.
Eur Geriatr Med

PURPOSE: Delirium risk assessment in the acute-care setting generally does not account for frailty. The objective of this retrospective study was to identify factors associated with delirium, considering the interdependency of clinical variables with frailty syndrome in complex older patients. METHODS: The clinical records of 587 participants (248 M, median age 84) were reviewed, collecting clinical, anamnestic and pharmacological data. Frailty syndrome was assessed with the Clinical Frailty Scale (CFS). Delirium was the main study endpoint. The correlations of the considered anamnestic and clinical variables with delirium and its subtypes were investigated selecting only those variables not showing a high overlap with frailty. Correlations associated with a 25% excess of frequency of delirium in comparison with the average of the population were considered as statistically significant. RESULTS: Delirium was detected in 117 (20%) participants. The presence of one among age > 85 years old, CFS > 4 and invasive devices explained 95% of delirium cases. The main factors maximizing delirium incidence at the individual level were dementia, other psychiatric illness, chronic antipsychotic treatment, and invasive devices. The coexistence of three of these parameters was associated with a peak frequency of delirium, ranging from 57 to 61%, mostly hypoactive forms. CONCLUSIONS: In acute-care wards, frailty exhibited a strong association with delirium during hospitalization, while at the individual level, dementia and the use of antipsychotics remained important risk factors. Modern clinical prediction tools for delirium should account for frailty syndrome.




Acute cerebral dysfunction
Cognitive impairment
Geriatric emergency medicine


Total Records Found: 6015, showing 100 per page
Postoperative delirium is a risk factor of institutionalization after hip fracture: an observational cohort study Labaste, F. Delort, F. Ferré, F. Bounes, F. Reina, N. Valet, P. Dray, C. Minville, V. Front Med (Lausanne) 2023

hip fracture
orthopedic surgery
commercial or financial relationships that could be construed as a potential
conflict of interest.

Prognostic significance of delirium in patients with heart failure: a systematic review and meta-analysis Niu, Z. Zhou, J. Li, Y. Front Cardiovasc Med 2023

heart failure

Postoperative delirium in 47 379 individuals undergoing transcatheter aortic valve replacement: a systematic review and meta-analysis Ochani, S. Adnan, A. Siddiqui, A. Kalwar, A. Kukreja, S. Ahmad, M. Ashraf, M. H. Asghar, M. A. Ann Med Surg (Lond) 2023

Cam, Tavr, confusion assessment method, delirium, stroke, transcatheter aortic valve replacement

ICU Readmission in Injured Older Adults: Modifiable Risk Factors and Implications Agoubi, L. L. Reimel, B. A. Maine, R. G. O'Connell, K. M. Maier, R. V. McIntyre, L. K. J Trauma Acute Care Surg 2023

ICU, delirium, older adults, risk factors, readmission

Motorist disorientation syndrome; clinical features and vestibular findings Ainsworth, C. Davies, R. Colvin, I. Murdin, L. J Vestib Res 2023

*Vestibular Diseases/diagnosis
*Migraine Disorders
Motorist Disorientation Syndrome (MDS)

External validity of an automated delirium prediction model (DEMO) and comparison to the manual VMS-questions: a retrospective cohort study Ali, M. I. M. Kalkman, G. A. Wijers, C. H. W. Fleuren, Hwha Kramers, C. de Wit, Hajm Int J Clin Pharm 2023

Retrospective Studies
*Delirium/diagnosis/epidemiology/prevention & control
Automated model
External validation
Hospitalized patients
Prevention measures
Risk prediction

Role of Intraoperative Neuromonitoring to Predict Postoperative Delirium in Cardiovascular Surgery Al-Qudah, A. M. Ta'ani, O. A. Thirumala, P. D. Sultan, I. Visweswaran, S. Nadkarni, N. Kiselevskaya, V. Crammond, D. J. Balzer, J. Anetakis, K. M. Shandal, V. Subramanium, K. Subramanium, B. Sadhasivam, S. J Cardiothorac Vasc Anesth 2023

Eeg, Ionm, Ssep, cardiac, delirium, postoperative

Comparison of the hemodynamic effects of opioid-based versus lidocaine-based induction of anesthesia with propofol in older adults: a randomized controlled trial Amin, S. M. Hasanin, A. ElSayed, O. S. Mostafa, M. Khaled, D. Arafa, A. S. Hassan, A. Anaesth Crit Care Pain Med 2023

*Propofol/adverse effects
Analgesics, Opioid/therapeutic use
Anesthetics, Intravenous
*Emergence Delirium
Anesthesia, General
*Hypotension/chemically induced/epidemiology
Norepinephrine/therapeutic use
General anesthesia
Older adult

Effect of pharmacist-led intervention protocol on preventing postoperative delirium after elective cardiovascular surgery Asai, Y. Yanagawa, T. Takahashi, M. PLoS One 2023

Adult, Humans, *Emergence Delirium, Pharmacists, Retrospective Studies, Benzodiazepines/adverse effects

Taming Postoperative Delirium with Dexmedetomidine: A Review of the Therapeutic Agent's Neuroprotective Effects following Surgery Bargnes, V., 3rd Oliver, B. Wang, E. Greenspan, S. Jin, Z. Yeung, I. Bergese, S. Pharmaceuticals (Basel) 2023

perioperative neurocognitive disorder
postoperative delirium

Level of implementation of pain management and early mobilization strategies to prevent delirium in geriatric trauma patients: A mixed-methods study Beaudoin, M. Belzile, E. L. Gélinas, C. Trépanier, D. Émond, M. Gagnon, M. A. Bérubé, M. Int J Orthop Trauma Nurs 2023

Delirium, Early mobilization, Geriatric trauma, Mixed-methods, Pain management, Practice guidelines

Dose-dependent QTc interval prolongation under haloperidol and pipamperone in the management of delirium in a naturalistic setting Bohny, P. Boettger, S. Jenewein, J. Front Psychiatry 2023

QTc interval, delirium, haloperidol, pipamperone, torsades de pointes

Prevalence and risk factors of subsyndromal delirium among postoperative patients: A systematic review and meta-analysis Chen, S. Tang, L. Chen, J. Cai, L. Liu, C. Song, J. Chen, Y. Liu, Y. Zheng, S. J Adv Nurs 2023

Subsyndromal delirium, meta-analysis, nurse, nursing, postoperative care, prevalence, risk factors, surgery

Incidence change of postoperative delirium after implementation of processed electroencephalography monitoring during surgery: a retrospective evaluation study Chen, Y. C. Hung, I. Y. Hung, K. C. Chang, Y. J. Chu, C. C. Chen, J. Y. Ho, C. H. Yu, C. H. BMC Anesthesiol 2023

*Emergence Delirium/diagnosis/epidemiology/complications
Postoperative Complications/diagnosis/epidemiology/prevention & control
Retrospective Studies
Anesthesia, General/adverse effects/methods
General anesthesia
Intravenous patient-controlled analgesia
Postoperative delirium
Processed electroencephalography

Incidence and risk factors for postoperative delirium after head and neck cancer surgery: an updated meta-analysis Dong, B. Yu, D. Jiang, L. Liu, M. Li, J. BMC Neurol 2023

*Emergence Delirium/complications/epidemiology/prevention & control
Postoperative Complications/etiology
Risk Factors
*Head and Neck Neoplasms/epidemiology/surgery
Head and neck cancer
Postoperative delirium
Systematic review

Five-year stroke prognosis. Influence of post-stroke delirium and post-stroke dementia on mortality and disability (Research Study - Part of the PROPOLIS Study) Droś, J. Segiet, N. Początek, G. Klimkowicz-Mrowiec, A. Neurol Sci 2023

Cognition disorders, Delirium, Dementia, Mortality, Stroke

Comparison of continuous sedatives in the burn ICU on delirium and coma Falksen, J. Young, S. R. Lee, J. A. J Burn Care Res 2023

burn, coma, delirium, sedation

Associations between depression symptom burden and delirium risk: a prospective cohort study Gaba, A. Li, P. Xi, Z. Gao, C. Ruixue, C. Hu, K. Gao, L. medRxiv 2023

Altered mental status
Alzheimer’s disease

Delirium and Previous Psychiatric History Independently Predict Poststroke Posttraumatic Stress Disorder Griffin, T. T. Bhave, V. McNulty, J. Christophe, B. R. Garton, A. L. A. Sander Connolly, E., Jr. Neurologist 2023

Humans, Female, *Stress Disorders, Post Traumatic/epidemiology/etiology/diagnosis, *Stroke/complications/epidemiology, *Delirium/diagnosis/epidemiology/etiology

Incidence of Postoperative Delirium in Cancer Patients After Head and Neck Surgery: A Proportional Meta-analysis Ho, M. H. Li, P. W. C. Lin, Y. K. Lee, J. J. Lin, C. C. Otolaryngol Head Neck Surg 2023

cancer, delirium, head and neck cancer, incidence, postoperative, proportional Meta-analysis

Triglyceride-glucose index as a valuable predictor for aged 65-years and above in critical delirium patients: evidence from a multi-center study Huang, X. Cheng, H. Yuan, S. Ling, Y. Tan, S. Tang, Y. Niu, C. Lyu, J. BMC Geriatr 2023

*Critical Care
Databases, Factual
Blood Glucose
Risk Factors
Critical care
Insulin resistance
Older adults
Triglyceride glucose index

Reliability and Validity of the Spanish Adaptation of the Stanford Proxy Test for Delirium in 2 Clinical Spanish-Speaking Communities Infante, S. Behn, A. González, M. Pintor, L. Franco, E. Araya, P. Maldonado, J. R. J Acad Consult Liaison Psychiatry 2023

Stanford proxy test for delirium, confusion assessment method, delirium, delirium and COVID, factor analysis

Association between preoperative neutrophil-lymphocyte ratio, uric acid, and postoperative delirium in elderly patients undergoing degenerative spine surgery Kato, K. Kinoshita, H. Kumagai, G. Takekawa, D. Nitobe, Y. Asari, T. Wada, K. Kushikata, T. Ishibashi, Y. Hirota, K. J Anesth 2023

Neuroprotection, Neutrophil–lymphocyte ratio, Postoperative delirium, Spine surgery, Uric acid

Preoperative assessment of postoperative delirium: a cross-sectional study of patients and anesthesiologists in Canada Khaled, M. Youssef, N. Choi, S. Uppal, V. Chui, J. Marcucci, M. Madden, K. Shanthanna, H. Can J Anaesth 2023

*Emergence Delirium
Cross-Sectional Studies
Risk Factors
Postoperative Complications/etiology
older adults
postoperative delirium
preoperative screening
risk reduction
shared decision-making

Resting-state prefrontal EEG biomarker in correlation with postoperative delirium in elderly patients Kim, J. Park, S. Kim, K. N. Ha, Y. Shin, S. J. Cha, W. Lee, K. Y. Choi, J. Koo, B. N. Front Aging Neurosci 2023

elderly, electroencephalography, median dominant frequency, postoperative complications, postoperative delirium

Risk of delirium with antiepileptic drug use: a study based on the Japanese Adverse Drug Event Report database Kubo, T. Sogawa, R. Tsuruhashi, S. Murakawa-Hirachi, T. Matsuoka, A. Mizoguchi, Y. Monji, A. Shimanoe, C. Int J Clin Pharm 2023

Anticonvulsants/adverse effects
Receptors, GABA-A
East Asian People
*Drug-Related Side Effects and Adverse Reactions
*Delirium/chemically induced/epidemiology/drug therapy
Adverse event
Antiepileptic drugs

Optimizing delirium care in the era of Age-Friendly Health System Kwak, M. J. Inouye, S. K. Fick, D. M. Bonner, A. Fulmer, T. Carter, E. Tabbush, V. Maya, K. Reed, N. Waszynski, C. Oh, E. S. J Am Geriatr Soc 2023

Age-Friendly Health System, Hospital Elder Life Program, delirium

Risk factors for hyperactive delirium after laparoscopic radical gastrectomy under general anesthesia in patients with gastric cancer Liu, J. Zhong, Q. Tan, H. Zhuo, M. Zhong, M. Cai, T. Am J Transl Res 2023

Laparoscopic radical gastrectomy, general anesthesia, hyperactive delirium, risk factors

Risk factors associated with postoperative delirium in elderly patients undergoing hip surgery Liu, X. H. Zhang, Q. F. Liu, Y. Lu, Q. W. Wu, J. H. Gao, X. H. Chen, Z. Y. Front Psychiatry 2023

elderly retrospective study
hip surgery
postoperative delirium

The influence of delirium on mortality and length of ICU stay and analysis of risk factors for delirium after liver transplantation Ma, Y. Li, C. Peng, W. Wan, Q. ATS Sch 2023

ICU stay
liver transplantation
risk factors

Hyperactive delirium during emergency department stay: analysis of risk factors and association with short-term outcomes Miró, Ò Osorio, G. Alquézar-Arbé, A. Aguiló, S. Fernández, C. Burillo, G. Jacob, J. Llorens, P. Llauger, L. Peláez González, Á Figuera Castro, E. R. Juarez González, R. Blanco Hoffman, M. J. Fernandez Salgado, F. Pablos Pizarro, T. Berenguer Dí Intern Emerg Med 2023

Benzodiazepines, Delirium, Emergency department, Mortality, Neuroleptics, Outcome

Delirium and neuropsychological recovery among emergency general surgery survivors (DANE): study protocol for a randomized controlled trial and collaborative care intervention Mohanty, S. Holler, E. Ortiz, D. Meagher, A. Perkins, A. Bylund, P. Khan, B. Unverzagt, F. Xu, H. Ingraham, A. Boustani, M. Zarzaur, B. Trials 2023

Treatment Outcome
Randomized Controlled Trials as Topic
Multicenter Studies as Topic
Emergency general surgery
Postoperative delirium

A randomized, clinical trial investigating the use of a digital intervention to reduce delirium-associated agitation Nicholas, M. Wittmann, J. Norena, M. Ornowska, M. Reynolds, S. NPJ Digit Med 2023

delirium, agitation, digital, RASS

Cognitive Deficits in Executive and Language Functions Predict Postoperative Delirium Olotu, C. Lebherz, L. Ascone, L. Scherwath, A. Kühn, S. Härter, M. Kiefmann, R. J Cardiothorac Vasc Anesth 2023

*Emergence Delirium/diagnosis/epidemiology/etiology
Postoperative Complications/diagnosis/epidemiology/etiology
Prospective Studies
*Cognitive Dysfunction/diagnosis/epidemiology/etiology
Risk Factors
neurocognitive disorders
older adults
postoperative delirium
preoperative assessment

Development of post-anesthesia care unit delirium is associated with differences in aperiodic and periodic alpha parameters of the EEG during emergence from general anesthesia - results from a prospective observational cohort study Ostertag, J. Engelhard, A. Nuttall, R. Aydin, D. Schneider, G. García, P. S. Hinzmann, D. Sleigh, J. W. Kratzer, S. Kreuzer, M. Anesthesiology 2023

PACU, delirium, EEG, hypnosis, alpha

Subsyndromal Delirium in Critically Ill Patients-Cognitive and Functional Long-Term Outcomes Paulino, M. C. Conceição, C. Silvestre, J. Lopes, M. I. Gonçalves, H. Dias, C. C. Serafim, R. Salluh, J. I. F. Póvoa, P. J Clin Med 2023

Icu, cognitive dysfunction delirium, long-term outcome, subsyndromal delirium

Prevalence of delirium in gastroenterology/hepatology units: A cross-sectional study Pazouki, R. Hasselblatt, P. Kugler, C. Z Gastroenterol 2023

Middle Aged
Cross-Sectional Studies
*Liver Cirrhosis/complications
Aged, 80 and over
*Hepatic Encephalopathy/complications

Grip Strength is a Predictor for Subsyndromal Delirium Among Older Adults Following Joint Replacement Qian, J. Shen, X. Gao, X. Sun, Q. Clin Interv Aging 2023

*Arthroplasty, Replacement
*Emergence Delirium
Postoperative Complications/diagnosis/epidemiology/etiology
Risk Factors
*Hand Strength
grip strength
joint replacement
risk factor
subsyndromal delirium

Prevalence and Risk Factors of Delirium in Patients Admitted to Intensive Care Units: A Multicentric Cross-Sectional Study Sadaf, F. Saqib, M. Iftikhar, M. Ahmad, A. Cureus 2023

critical illness, delirium, intensive care units, pakistan, prevalence

Perioperative Factors Associated With Postoperative Delirium in Patients Undergoing Noncardiac Surgery: An Individual Patient Data Meta-Analysis Sadeghirad, B. Dodsworth, B. T. Schmutz Gelsomino, N. Goettel, N. Spence, J. Buchan, T. A. Crandon, H. N. Baneshi, M. R. Pol, R. A. Brattinga, B. Park, U. J. Terashima, M. Banning, L. B. D. Van Leeuwen, B. L. Neerland, B. E. Chuan, A. Martinez, F. T. Van JAMA Netw Open 2023

*Emergence Delirium/epidemiology/etiology
Postoperative Complications/epidemiology/etiology/diagnosis
Risk Factors

Thirty-day mortality among patients with acute delirium in the emergency department Sanguanwit, P. Ninlamal, S. Prachanukool, T. Heliyon 2023

30-Day mortality, Delirium, Emergency department, Older-patients

Role of hypoxia-inducible factor in postoperative delirium of aged patients: A review Shen, H. Yang, J. Chen, X. Gao, Y. He, B. Medicine (Baltimore) 2023

Infant, Newborn, Humans, Aged, *Emergence Delirium, Transcription Factors/metabolism, Hypoxia, Ischemia, *Anesthetics, Hypoxia-Inducible Factor 1, alpha Subunit

The efficacy of earplugs and eye masks for delirium severity and sleep quality in patients undergoing coronary artery bypass grafting in cardiac intensive care units: A single-blind, randomised controlled trial Shorofi, S. A. Dadashian, P. Arbon, P. Moosazadeh, M. Aust Crit Care 2023

Coronary artery bypass grafting, Delirium, Earplugs, Eye masks, ICU psychosis, Sleep quality

Efficacy of haloperidol to decrease the burden of delirium in adult critically ill patients: the EuRIDICE randomized clinical trial Smit, L. Slooter, A. J. C. Devlin, J. W. Trogrlic, Z. Hunfeld, N. G. M. Osse, R. J. Ponssen, H. H. Brouwers, Ajbw Schoonderbeek, J. F. Simons, K. S. van den Boogaard, M. Lens, J. A. Boer, D. P. Gommers, Dampj Rietdijk, W. J. R. van der Jagt, M. Crit Care 2023

Middle Aged
*Antipsychotic Agents/adverse effects
Critical Illness/therapy
Intensive Care Units
Quality of Life
Critical care
Randomized controlled trial

Efficacy of haloperidol to decrease the burden of delirium in adult critically ill patients: the EuRIDICE randomized clinical trial Smit, L. Slooter, A. J. C. Devlin, J. W. Trogrlic, Z. Hunfeld, N. G. M. Osse, R. J. Ponssen, H. H. Brouwers, Ajbw Schoonderbeek, J. F. Simons, K. S. van den Boogaard, M. Lens, J. A. Boer, D. P. Gommers, Dampj Rietdijk, W. J. R. van der Jagt, M. Crit Care 2023

Middle Aged
*Antipsychotic Agents/adverse effects
Critical Illness/therapy
Intensive Care Units
Quality of Life
Critical care
Randomized controlled trial

Effectiveness of a Multi-component Delirium Prevention Program Implemented on General Medicine Hospital Units: an Interrupted Time Series Analysis Versloot, J. Minotti, S. C. Amer, S. Ali, A. Ma, J. Peters, M. L. Saab, H. Tang, T. Kerr, J. Reid, R. J Gen Intern Med 2023

Adult, Humans, Aged, Aged, 80 and over, Interrupted Time Series Analysis, Retrospective Studies, *Delirium/diagnosis/epidemiology/prevention & control, Hospitals, Community, Ontario, Hospital Units, delirium prevention, delirium program, inpatients, internal medicine

Delirium During Critical Illness and Subsequent Change of Treatment in Patients With Cancer: A Mediation Analysis Vizzacchi, B. A. Dettino, A. L. A. Besen, Bamp Caruso, P. Nassar, A. P., Jr. Crit Care Med 2023

IUC, delirium, cohort, cancer, CAM

Efficacy and moderators of prevention and treatment of delirium with melatonin receptor agonists: A systematic review and meta-analysis of randomized controlled trials Wada, M. Yasuda, H. Nakajima, S. Etani, T. Miura, A. Asada, S. Yoshida, K. Noda, Y. Takeuchi, H. Gen Hosp Psychiatry 2023

Melatonin receptor agonists

Intraoperative body temperature and emergence delirium in elderly patients after non-cardiac surgery: A secondary analysis of a prospective observational study Wang, G. He, S. Yu, M. Zhang, Y. Mu, D. Wang, D. Chin Med J (Engl) 2023

Body Temperature
*Emergence Delirium
Postoperative Complications/epidemiology
Prospective Studies

Relationship between preoperative neutrophil-to-lymphocyte ratio and postoperative delirium: The PNDABLE and the PNDRFAP cohort studies Wu, X. Chi, F. Wang, B. Liu, S. Wang, F. Wang, J. Tang, X. Bi, Y. Lin, X. Li, J. Brain Behav 2023

Alzheimer-related biomarkers
risk factor

Risk Factors for Delirium Superimposed on Dementia in Elderly Patients in Comprehensive Ward Xiao, Q. Zhang, S. Li, C. Zhu, Y. Am J Alzheimers Dis Other Demen 2023

Retrospective Studies
*Alzheimer Disease/complications
Risk Factors
*Diabetes Mellitus
*Cerebrovascular Disorders
Superoxide Dismutase
Hypnotics and Sedatives
risk factor
senile dementia

Effect of postoperative delirium after cardiovascular surgery on 5-year mortality Yokoyama, C. Yoshitnai, K. Ogata, S. Fukushima, S. Matsuda, H. JA Clin Rep 2023

5-year mortality, Cardiopulmonary bypass, Cardiovascular surgery, Postoperative delirium

Association Between the Use of Midazolam During Cardiac Anesthesia and the Incidence of Postoperative Delirium: A Retrospective Cohort Study Using a Nationwide Database Yoshimura, M. Hidaka, Y. Morimoto, Y. J Cardiothorac Vasc Anesth 2023

Humans, *Emergence Delirium/epidemiology, Midazolam/adverse effects, Retrospective Studies, Incidence, Postoperative Nausea and, Vomiting/chemically induced/epidemiology, *Anesthesia, Cardiac Procedures, Postoperative, Complications/chemically induced/epidemiology, Diagnosis Procedure, Combination data, cardiac surgery, midazolam, postoperative delirium, stabilized inverse probability of treatment

Associations of Delirium to Posthospital Outcomes After Acute Stroke: A Scoping Review Young, B. C. Rhoten, B. A. J Neurosci Nurs 2023

Adult, Humans, Adolescent, *Dexmedetomidine/therapeutic use, Palliative Care, *Pain, Intractable/drug therapy/chemically induced, Hypnotics and, Sedatives/therapeutic use, Retrospective Studies, *Delirium/drug therapy, Intensive Care Units

Dexmedetomidine use for patients in palliative care with intractable pain and delirium: A retrospective study Yu, S. Y. Schellenberg, J. Alleyne, A. PLoS One 2023

Adult, Humans, Adolescent, *Dexmedetomidine/therapeutic use, Palliative Care, *Pain, Intractable/drug therapy/chemically induced, Hypnotics and, Sedatives/therapeutic use, Retrospective Studies, *Delirium/drug therapy, Intensive Care Units

Validity and predictability of the confusion assessment method for the intensive care unit for delirium among critically ill patients in the intensive care unit: A systematic review and meta-analysis Zhang, Y. Diao, D. Zhang, H. Gao, Y. Nurs Crit Care 2023

Cam-icu, critical, delirium, intensive care unit

Impact of nursing interventions on discharge disposition in patients with postoperative delirium Zhao, Y. Quon, A. Luke, K. Tivis, L. J. Nursing 2023

Humans, Aged, Patient Discharge, Retrospective Studies, *Emergence Delirium, *Hypoalbuminemia, Hospitalization

Causal relationships between delirium and Alzheimer's disease: a bidirectional two-sample Mendelian randomization study Zheng, J. Du, X. Yang, L. Fu, H. Eur J Med Res 2023

Humans, *Alzheimer Disease/genetics, Genome-Wide Association Study, Mendelian Randomization Analysis, Risk Factors, Nonoxynol, Alzheimer’s disease, Causal relationships, Delirium, European, Mendelian randomization

Circadian rhythm disturbance and delirium in ICU patients: a prospective cohort study Li, J. Cai, S. Liu, X. Mei, J. Pan, W. Zhong, M. Zhang, Y. Medicine (Baltimore) 2023

United States, Humans, *Hydrocortisone, *Melatonin, Prospective Studies, Circadian Rhythm, Intensive Care Units, Cortisol, Delirium, Melatonin

Amantadine-associated delirium in patients with maintenance dialysis: Insomnia-associated recovery and uneven seasonal distribution Li, J. Si, B. Chao, J. He, J. Medicine (Baltimore) 2023

Humans, Renal Dialysis, Retrospective Studies, Seasons, *Sleep Initiation and Maintenance Disorders/drug therapy, Amantadine/adverse effects, *Delirium/chemically induced/epidemiology

Effects of Different Injection Rates of Propofol on Postoperative Cognition in Elderly Patients Undergoing Laparoscopic Inguinal Hernia Repair Li, T. Han, W. Yang, X. Wang, Y. Peng, L. He, L. Hu, L. Liu, J. Xia, M. Wang, S. Drug Des Devel Ther 2023

Humans, Aged, *Propofol/adverse effects, Anesthetics, Intravenous/adverse effects, *Hernia, Inguinal/surgery/chemically induced, Postoperative, Complications/epidemiology, Cognition, *Delirium, *Laparoscopy, bispectral index, burst suppression, elderly, injection rate, postoperative cognitive decline, propofol

The Effect of Music as a Non-Pharmacological Intervention on the Physiological, Psychological, and Social Response of Patients in an Intensive Care Unit Lorek, M. Bąk, D. Kwiecień-Jaguś, K. Mędrzycka-Dąbrowska, W. Healthcare (Basel) 2023

classical music, delirium, intensive care unit, music perception, music therapy, nursing, pain, therapeutic music listening

Feasibility of a Modified Otago Exercise Program for Older Adults With Cognitive Vulnerability Mangione, K. K. Darreff, H. Welsh, M. Ni, W. Wolff, E. Booth, J. T. Glenney, S. S. Fortinsky, R. H. J Appl Gerontol 2023

Humans, Aged, Exercise Therapy, Feasibility Studies, Postural Balance, *Dementia/therapy, Cognition, *Delirium, Otago exercise program, dementia, depression, exercise, feasibility, older adult

Accuracy of Delirium Screening Tools in Older People with Cancer-A Systematic Review Martínez-Arnau, F. M. Puchades-García, A. Pérez-Ros, P. Cancers (Basel) 2023

accuracy, aged, assessment, cancer, delirium, incidence, prevalence, psychometric properties

Evaluation of the delirium preventive effect of dual orexin receptor antagonist (DORA) in critically ill adult patients requiring ventilation with tracheal intubation at an advanced emergency center: A single-center, retrospective, observational study Matsuoka, A. Sogawa, R. Murakawa-Hirachi, T. Mizoguchi, Y. Monji, A. Shimanoe, C. Shinada, K. Koami, H. Sakamoto, Y. J Alzheimers Dis 2023

Humans, Adult, Adolescent, *Orexin Receptor Antagonists/adverse effects, Retrospective Studies, Critical Illness/therapy, *Delirium/prevention & control/epidemiology, Intubation, Intratracheal, Delirium, Intensive care unit, Lemborexant, Sleep disorder, Suvorexant

Individualized Summary Assessment of Detailed Neuropsychological Testing for the Etiological Diagnosis of Newly Detected Cognitive Impairment in Hospitalized Geriatric Patients Mäurer, A. Himmel, G. Lange, C. Mathies, F. Apostolova, I. Peters, O. Buchert, R. J Alzheimers Dis 2023

Alzheimer’s disease, delirium, dementia, etiological diagnosis, hospitalized, geriatric patients, neuropsychological testing

A systematic review of studies reporting on neuropsychological and functional domains used for assessment of recovery from delirium in acute hospital patients McCartney, H. Noble, E. MacLullich, A. M. J. Davis, D. H. J. Evans, J. Shenkin, S. D. Muniz-Terrera, G. Sandeman, D. Tieges, Z. Int J Geriatr Psychiatry 2023

Humans, *Activities of Daily Living, *Delirium/diagnosis/drug therapy
Hospitals, 4at, delirium assessment, delirium recovery, functional recovery, longitudinal studies, neuropsychological domains, repeat assessment

Implementing a ward-based programme to improve care for older inpatients: process evaluation of the cluster randomised CHERISH trial Mudge, A. M. McRae, P. Young, A. Blackberry, I. Lee-Steere, K. Barrimore, S. Quirke, T. Harvey, G. BMC Health Serv Res 2023

Aged, Humans, *Delirium/prevention & control, Hospitals, *Inpatients, Nutritional Status, Prospective Studies, Age-friendly hospitals, Delirium, Evaluation, Facilitation, Implementation

Effect of laparoscopic liver resection on postoperative delirium in elderly patients with hepatocellular carcinoma Nomi, T. Kaibori, M. Hirokawa, F. Ueno, M. Hokuto, D. Noda, T. Nakai, T. Ikoma, H. Iida, H. Kubo, S. J Hepatobiliary Pancreat Sci 2023

elderly patients, hepatocellular carcinoma, laparoscopic liver resection, postoperative delirium

Development of a scale measuring the difficulties faced by nurses who care for patients with delirium in intensive care units Owaki, N. Tanaka, M. Kawakami, A. Aust Crit Care 2023

Humans, Reproducibility of Results, Pilot Projects, Intensive Care Units, Surveys and Questionnaires, *Delirium, *Nurses, Psychometrics/methods, Delirium, Exploratory factor analysis, Nurse, Psychological distress, Scale development

Preliminary evaluation of a smartphone application (DelApp) for identification of delirium in sub-Saharan Africa Paddick, S. M. Gamassa, E. Mwaluwinga, N. Lewis, G. Duinmaijer, A. Urasa, S. Tucker, L. Mukaetova-Ladinska, E. B. Cosker, G. Dekker, M. Kisoli, A. Cletus, J. Lissu, C. Dotchin, C. Gray, W. K. Walker, R. Acta Neuropsychiatr 2023

Africa, cognitive assessment, delirium, screening

Postoperative delirium after cholecystectomy in older patients: A retrospective study Park, Y. M. Seo, H. I. Noh, B. G. Kim, S. Hong, S. B. Lee, N. K. Kim, D. U. Han, S. Y. Ann Hepatobiliary Pancreat Surg 2023

Body mass index, Cholecystectomy, Delirium, Nutrition, Older patients

Exploring the Documentation of Delirium in Patients After Cardiac Surgery: A Retrospective Patient Record Study Poikajärvi, S. Peltonen, L. M. Siirala, E. Heimonen, J. Moen, H. Salanterä, S. Junttila, K. Comput Inform Nurs 2023

delirium, cardiac, surgery, EHR, documentation

The Efficacy of Low-Dose Risperidone Treatment for Post-Surgical Delirium in Elderly Orthopedic Patients Raphael, L. Edna, E. Irina, K. Oded, H. Medicina (Kaunas) 2023

Female, Humans, Aged, Aged, 80 and over, Male, Risperidone/adverse effects, Prospective Studies, *Delirium/drug therapy/etiology/diagnosis, *Orthopedics, Postoperative Complications/drug therapy, delirium, elderly, post-surgical, protocol, risperidone

Serum Biomarkers of a Pro-Neuroinflammatory State May Define the Pre-Operative Risk for Postoperative Delirium in Spine Surgery Ruhnau, J. Müller, J. Nowak, S. Strack, S. Sperlich, D. Pohl, A. Dilz, J. Saar, A. Veser, Y. Behr, F. Rehberg, S. Usichenko, T. Hahnenkamp, K. Ehler, J. Flöel, A. Schroeder, H. W. S. Müller, J. U. Fleischmann, R. Vogelgesang, A. Int J Mol Sci 2023

Humans, Aged, *Emergence Delirium, Interleukin-6/metabolism, *Delirium/diagnosis/etiology, Gasdermins, Postoperative, Complications/etiology, Prospective Studies, Biomarkers/metabolism, Gasdermin D, biomarker, postoperative cognitive dysfunction, postoperative delirium, sTREM2, spine surgery

Effects of an interactive handgrip game on surgical patients requiring intensive care: An assessor-blinded randomized controlled trial Han, P. H. Shih, C. Y. Wang, A. Y. Chen, Y. C. Yang, C. C. Fan, Y. C. Hsiang, H. F. Chiu, H. Y. Intensive Crit Care Nurs 2023

Critically ill patients, Handgrip strength, Interactive handgrip game, Psychological distress

A critical appraisal and recommendation synthesis of delirium clinical practice guidelines relevant to the care of older adults in the emergency department: An umbrella review Filiatreault, S. Grimshaw, J. M. Kreindler, S. A. Chochinov, A. Linton, J. Chatterjee, R. Azeez, R. Doupe, M. B. J Eval Clin Pract 2023

Agree, aged, delirium, emergency services (hospital), practice guideline, systematic review

Implementation of a novel nursing assessment tool in geriatric trauma patients with proximal femur fractures Berk, T. Thalmann, M. Jensen, K. O. Schwarzenberg, P. Jukema, G. N. Pape, H. C. Halvachizadeh, S. PLoS One 2023

Humans, Aged, Retrospective Studies, *Proximal Femoral Fractures, *Delirium/etiology/complications, Risk Factors, Nutritional Status, Geriatric Assessment

Enhanced recovery after surgery in patients with normal pressure hydrocephalus undergoing ventriculoperitoneal shunting procedures Ali, A. Gupta, B. Johansen, P. Santiago, R. B. Dabecco, R. Mandel, M. Adada, B. Botero, J. Roy, M. Borghei-Razavi, H. Clin Neurol Neurosurg 2023

Humans, Ventriculoperitoneal Shunt/adverse effects, *Hydrocephalus, Normal Pressure/surgery/complications, *Enhanced Recovery After Surgery, Postoperative Complications/etiology, *Delirium/complications/surgery, Length of Stay, Retrospective Studies, Delirium, Eras, Neurosurgery, Normal pressure hydrocephalus, Ventriculoperitoneal shunting

The use of patient sitters at a Swiss hospital: A retrospective observational study Kramer, I. Schubert, M. PLoS One 2023

Aged, Humans, Confusion, *Ethnicity, Hospitals, *Inpatients, Retrospective Studies, Switzerland, Aged, 80 and over

The role of inflammatory parameters in the prediction of postoperative delirium in patients undergoing coronary artery bypass grafting Şaşkin, H. Özcan, K. S. Yildirim, S. Cardiovasc J Afr 2023

Humans, *Emergence Delirium/etiology, Retrospective Studies, Postoperative Complications/diagnosis/etiology, Coronary Artery Bypass/adverse effects, Risk Factors, coronary artery bypass grafting surgery, delirium, inflammation

Opioids increase the risk of delirium in critically ill patients: A propensity score analysis Shi, H. J. Zhang, X. P. Hai, C. Shi, W. Wang, P. Hu, A. M. Int J Clin Pharmacol Ther 2023

Humans, *Analgesics, Opioid/adverse effects, Intensive Care Units, Critical, Illness/therapy, Propensity Score, Risk Factors, *Delirium/chemically induced/diagnosis/epidemiology

Characteristics of delirium and its association with sedation and in-hospital mortality in patients with COVID-19 on veno-venous extracorporeal membrane oxygenation Sun, P. Y. Fanning, J. Peeler, A. Shou, B. Lindsley, J. Caturegli, G. Whitman, G. Cha, S. Kim, B. S. Cho, S. M. Front Med (Lausanne) 2023

analgesia, deep sedation, delirium, extracorporeal membrane oxygenation, hospital mortality

Delirium as a Risk Factor for Mortality in Critically Ill Patients With Cancer Tao, J. Seier, K. Marasigan-Stone, C. B. Simondac, J. S. Pascual, A. V. Kostelecky, N. T. SantaTeresa, E. Nwogugu, S. O. Yang, J. J. Schmeltz, J. Tan, K. S. Chawla, S. Voigt, L. P. JCO Oncol Pract 2023

Humans, Female, Middle Aged, Aged, Male, *Delirium/diagnosis/prevention & control, Critical Illness, Risk Factors, Intensive Care Units, *Neoplasms

Effectiveness of sleep interventions to reduce delirium in critically ill patients: A systematic review and meta-analysis Teng, J. Qin, H. Guo, W. Liu, J. Sun, J. Zhang, Z. J Crit Care 2023

Critical illness, Delirium, ICUs, Meta-analysis, Sleep

Chlorpromazine's Potential Role in Palliating Distressing Symptoms Associated With Hyperactive Delirium in Patients at End of Life Tiefenthaler, C. M. Hirst, J. M. Edmonds, K. P. Atayee, R. S. J Palliat Med 2023

Humans, Chlorpromazine/therapeutic use, Psychomotor Agitation/drug therapy/complications/prevention & control, *Delirium/drug therapy, *Neoplasms/complications, Death, Palliative Care, chlorpromazine
end of life, hyperactive delirium, proportionate sedation

Delirium and IL-6 added to clinical scores improves their performance: a prospective analysis of CALL, PREDI-CO, MRS score applied to a population of patients admitted to internal medicine ward Vannucchi, V. Pelagatti, L. Barone, F. Bertini, L. Celli, T. Boccia, N. Veneziani, F. Cimolato, B. Landini, G. Intern Emerg Med 2023

Call, Covid-19, Delirium,il-6, Mrs, Outcome, Predi-co, Score

Electroencephalographic Biomarkers, Cerebral Oximetry, and Postoperative Cognitive Function in Adult Non-Cardiac Surgical Patients: a Prospective Cohort Study Vlisides, P. E. Li, D. Maywood, M. Zierau, M. Lapointe, A. P. Brooks, J. McKinney, A. M. Leis, A. M. Mentz, G. Mashour, G. A. Anesthesiology 2023

Adult, Humans, Retrospective Studies, Prospective Studies, *Delirium/diagnosis/epidemiology/etiology, Critical Illness, Intensive Care Units, Critically ill, Delirium, Intensive care unit, Machine learning, Prediction

Early prediction of delirium upon intensive care unit admission: Model development, validation, and deployment Wang, M. L. Kuo, Y. T. Kuo, L. C. Liang, H. P. Cheng, Y. W. Yeh, Y. C. Tsai, M. T. Chan, W. S. Chiu, C. T. Chao, A. Chou, N. K. Yeh, Y. C. Ku, S. C. J Clin Anesth 2023

Adult, Humans, Retrospective Studies, Prospective Studies, *Delirium/diagnosis/epidemiology/etiology, Critical Illness, Intensive Care Units, Critically ill, Delirium, Intensive care unit, Machine learning, Prediction

Perioperative cerebral perfusion in aortic arch surgery: a potential link with neurological outcome Weijs, R. W. J. Tromp, S. C. Heijmen, R. H. Seeber, A. A. van Belle-van Haaren, Njcw Claassen, Jahr Thijssen, D. H. J. Eur J Cardiothorac Surg 2023

Humans, Aorta, Thoracic/diagnostic imaging/surgery, *Brain Ischemia/etiology/prevention & control, Retrospective Studies, *Stroke/etiology/prevention & control, Perfusion, *Ischemic Stroke, Cerebrovascular Circulation/physiology, *Delirium, Treatment Outcome, Postoperative Complications/prevention & control, *Aortic Aneurysm, Thoracic/surgery, Antegrade selective cerebral perfusion, Aortic surgery, Cerebral circulation, Perioperative management, Postoperative complication, Thoracic aorta

Preoperative Cognitive Impairment and Postoperative Delirium in Elderly Surgical Patients: A Retrospective Large Cohort Study (The CIPOD Study) Weiss, Y. Zac, L. Refaeli, E. Ben-Yishai, S. Zegerman, A. Cohen, B. Matot, I. Ann Surg 2023

Humans, Aged, *Emergence Delirium/complications, *Delirium/diagnosis/epidemiology/etiology, Retrospective Studies, Cohort Studies, Prospective Studies, *Cognitive Dysfunction/diagnosis/epidemiology, Postoperative Complications/etiology, Risk Factors

Contribution of Different Brain Disorders and Multimorbidity to Delirium Superimposed Dementia (DSD) Wetterling, T. Junghanns, K. Geriatrics (Basel) 2023

brain infarction, deliriumm dementia, multimorbidity, white matter hyperintensities

Prevalence and Risk Factors for Intensive Care Unit Delirium After Traumatic Brain Injury: A Retrospective Cohort Study Wilson, L. D. Maiga, A. W. Lombardo, S. Nordness, M. F. Haddad, D. N. Rakhit, S. Smith, L. F. Rivera, E. L. Cook, M. R. Thompson, J. L. Raman, R. Patel, M. B. Neurocrit Care 2023

Adult, Humans, Retrospective Studies, Prevalence, *Brain Injuries,, Traumatic/complications/epidemiology, Risk Factors, Intensive Care Units, *Subarachnoid Hemorrhage/complications, *Delirium/epidemiology/etiology, Glasgow Coma Scale,Critical illness, Delirium, Mental status, Predictors, Traumatic brain injury

Moderate-to-high risk of obstructive sleep apnea with excessive daytime sleepiness is associated with postoperative neurocognitive disorders: a prospective one-year follow-up cohort study Wu, W. Pu, L. Hu, X. Chen, Q. Wang, G. Wang, Y. Front Neurosci 2023

excessive daytime sleepiness, obstructive sleep apnea, older adults, perioperative neurocognitive disorders, surgery

Effect of Dexmedetomidine on Posttraumatic Stress Disorder in Patients Undergoing Emergency Trauma Surgery: A Randomized Clinical Trial Yu, Y. Li, Y. Han, D. Gong, C. Wang, L. Li, B. Yao, R. Zhu, Y. JAMA Netw Open 2023

Male, Humans, Adult, *Dexmedetomidine/therapeutic use/adverse effects, *Stress Disorders, Post-Traumatic/epidemiology/prevention & control, Saline Solution, *Emergence Delirium/chemically induced, Administration, Intravenous

Regional versus general anesthesia in older patients for hip fracture surgery: a systematic review and meta-analysis of randomized controlled trials Zhou, S. L. Zhang, S. Y. Si, H. B. Shen, B. J Orthop Surg Res 2023

Humans, Aged, Randomized Controlled Trials as Topic, *Hip Fractures/surgery, Anesthesia, General/adverse effects, *Plastic Surgery Procedures, *Delirium, Anesthesia, General, Hip fracture, Meta-analysis, Regional

Delirium in Medically Hospitalized Patients: Prevalence, Recognition and Risk Factors: A Prospective Cohort Study Al Farsi, R. S. Al Alawi, A. M. Al Huraizi, A. R. Al-Saadi, T. Al-Hamadani, N. Al Zeedy, K. Al-Maqbali, J. S. J Clin Med 2023

delirium, elderly, incidence, prevalence, risk factors

Delirium detection using wearable sensors and machine learning in patients with intracerebral hemorrhage Ahmed, A. Garcia-Agundez, A. Petrovic, I. Radaei, F. Fife, J. Zhou, J. Karas, H. Moody, S. Drake, J. Jones, R. N. Eickhoff, C. Reznik, M. E. Front Neurol 2023

actigraphy, delirium, intracerebral hemorrhage, machine learning, neurocritical care, stroke, wearable electronic devices

Associations of postoperative delirium with activities of daily living in older people after major surgery: A prospective cohort study Aldwikat, R. K. Manias, E. Holmes, A. C. Tomlinson, E. Nicholson, P. J Clin Nurs 2023

activities of daily living, cognition, older surgical patients, post-anaesthetic care unit, postoperative delirium

Association Between Risk of Stroke and Delirium After Cardiac Surgery and a New Electroencephalogram Index of Interhemispheric Similarity Baron Shahaf, D. Hight, D. Kaiser, H. Shahaf, G. J Cardiothorac Vasc Anesth 2023

Eeg, Lir, delirium, stroke