Delirium Bibliography

Delirium Bibliography books graphicWhat is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!

How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.

Reference Information

Title
Epidural vs. systemic analgesia in the Intensive Care Unit: retrospective study of patient outcomes
Authors
Naser, A. Meyer, A. Ifrach, N. Dichtwald, S.
Year
2024
Journal
Minerva Anestesiol
Abstract

BACKGROUND: Patients admitted to the Intensive Care Unit (ICU) often experience acute pain. Causes include major surgery, multisystem trauma, and pancreatitis. Most ICU patients who require pain management are treated with systemic analgesia, usually intravenous opioids. This study compared the rate of pain and delirium scores, as well as mortality and morbidity between ICU patients treated with systemic vs. epidural analgesia. METHODS: This retrospective analysis included patients who were in the ICU from January 2011 to June 2021, admitted due to thoracic, abdominal, pelvic, or lower limb surgery; pancreatitis; multiple rib fractures, or multisystem trauma. Data included demographics, admission parameters and indication, VAS score, Richmond Agitation and Sedation Score, in-hospital morbidity, and mortality, medical history, and medications. RESULTS: There was no significant difference in demographics, chronic medications, and past illness, excluding chronic obstructive pulmonary disease, peripheral vascular disease, and past cerebral vascular disease. ICU length of stay was shorter in the epidural group, but overall hospital length of stay was not. Except for increased need for dialysis in the systemic analgesia group, disease severity was similar in both groups. The epidural group had fewer days on mechanical ventilation and lower 28-day mortality, as well as fewer episodes of delirium, although pain scores were similar. There was no difference between groups in the need for physical restraints or antipsychotics for delirium. CONCLUSIONS: Epidural analgesia reduced the number of delirium events and was associated with a shorter ICU stay, fewer ventilation days and a lower mortality rate. Further research is needed to confirm these findings.

PMID

PMID:38015587

Keywords

Humans
Pain Management
Retrospective Studies
Pain
Intensive Care Units
*Analgesia, Epidural
*Delirium/epidemiology
*Pancreatitis
Length of Stay

Page(s)
Issue

Search:
Total Records Found: 6347, showing 100 per page
TitleAuthorsJournalYearKeywords
Living at home after emergency hospital admission: Prospective cohort study in older adults with and without cognitive spectrum disorder. Burton, J. K. Guthrie, B. Hapca, S. M. Cvoro, V. Donnan, P. T. Reynish, E. L. BMC Medicine 2018

aged
article
cognitive spectrum disorder
cohort analysis
controlled study
delirium
dementia
disease association
disorders of higher cerebral function
female
general hospital
geriatric assessment
health service
home care
hospital admission
hospital discharge
hospitalization
human
incidence
major clinical study
male
Older Person Routine Acute Assessment
outcome assessment
prospective study
residential home
risk factor
very elderly

The Association Between C-Reactive Protein and Postoperative Delirium Differs by Catechol-O-Methyltransferase Genotype. Vasunilashorn, S. M. Ngo, L. H. Jones, R. N. Inouye, S. K. Hall, K. T. Gallagher, J. Dillon, S. T. Xie, Z. Libermann, T. A. Marcantonio, E. R. American Journal of Geriatric Psychiatry 2019

acute phase protein
C reactive protein
catechol methyltransferase
DNA
valine
aged
article
cohort analysis
colon resection
controlled study
disease association
DNA extraction
enzyme linked immunosorbent assay
female
genetic association
genotype
human
major clinical study
male
orthopedic surgery
postoperative delirium
prospective study
protein blood level
vascular surgery

Risk factors associated with acute in-hospital delirium for patients diagnosed with a hip fracture in the emergency department. Thompson, C. Brienza, V. J. M. Sandre, A. Caine, S. Borgundvaag, B. McLeod, S. Canadian Journal of Emergency Medicine 2018

codeine
hydromorphone
morphine
oxycodone
paracetamol
adult
age
Alzheimer disease
analgesia
article
atrial fibrillation
breathing rate
cerebrovascular accident
confusion
congestive heart failure
Cushing disease
degenerative disease
delirium
dementia
depression
emergency ward
female
heart rate
hip fracture
hospital patient
human
hypertension
hyperthyroidism
hypothyroidism
length of stay
major clinical study
male
mental health
middle aged
osteoarthritis
osteoporosis
outcome assessment
oxygen saturation
Parkinson disease
retrospective study
risk factor
schizophrenia
systolic blood pressure

A Comparison of Early, Late, and No Treatment of Intensive Care Unit Delirium With Antipsychotics: A Retrospective Cohort Study. Thom, R. P. Bui, M. P. Rosner, B. Teslyar, P. Levy-Carrick, N. C. Klompas, M. The Primary Care Companion for CNS Disorders 2018

neuroleptic agent
coma
comparative study
critical illness
delirium
female
follow up
human
intensive care unit
male
middle aged
mortality
retrospective study
time factor
treatment outcome

Postoperative Pain Management Strategies and Delirium After Transapical Aortic Valve Replacement: A Randomized Controlled Trial. Strike, E. Arklina, B. Stradins, P. Cusimano, R. J. Osten, M. Horlick, E. Styra, R. Poonawala, H. Carroll, J. Djaiani, G. Journal of Cardiothoracic and Vascular Anesthesia 2018

adult
article
clinical article
comorbidity
contraindication
controlled study
dementia
demography
drug therapy
extubation
female
human
intensive care unit
male
morbidity
mortality
opiate addiction
patient controlled analgesia
postoperative delirium
postoperative pain
postoperative period
preoperative evaluation
prospective study
randomization
randomized controlled trial
regional anesthesia
sedation
Sedation Agitation Scale
staff
surgery
tertiary care center
transcatheter aortic valve implantation
university hospital
visual analog scale
local anesthetic agent
opiate

Effect of Depth of Sedation in Older Patients Undergoing Hip Fracture Repair on Postoperative Delirium: The STRIDE Randomized Clinical Trial. Sieber, F. E. Neufeld, K. J. Gottschalk, A. Bigelow, G. E. Oh, E. S. Rosenberg, P. B. Mears, S. C. Stewart, K. J. Ouanes, J. P. P. Jaberi, M. Hasenboehler, E. A. Li, T. Wang, N. Y. JAMA Surg 2018

local anesthetic agent
propofol
aged
anesthesia level
article
Charlson Comorbidity Index
double blind procedure
female
follow up
fracture treatment
hip fracture
hospital discharge
human
incidence
intention to treat analysis
intraoperative period
major clinical study
male
postoperative delirium
postoperative period
priority journal
spinal anesthesia

Incidence of Delirium in Critically Ill Cancer Patients. Sánchez-Hurtado, L. A. Hernández-Sánchez, N. Del Moral-Armengol, M. Guevara-García, H. García-Guillén, F. J. Herrera-Gómez, Á Ñamendys-Silva, S. A. Pain Research & Management 2018

adult
aged
cohort analysis
complication
critical illness
delirium
female
human
incidence
intensive care unit
male
middle aged
neoplasm
risk factor
severity of illness index

Dispersion in Scores on the Richmond Agitation and Sedation Scale as a Measure of Delirium in Patients with Subdural Hematomas. Robinson, D. Thompson, S. Bauerschmidt, A. Melmed, K. Couch, C. Park, S. Agarwal, S. Roh, D. Connolly, E. S. Claassen, J. Neurocritical Care 2018

adult
agitation
APACHE
article
cohort analysis
controlled study
delirium
diagnosis
female
functional disease
human
infection
major clinical study
male
monitoring
neurological intensive care unit
prospective study
Rankin scale
sedation
subdural hematoma
traumatic brain injury

Underdiagnosis of delirium in the elderly in acute care hospital settings: lessons not learned. Ritter, S. R. F. Cardoso, A. F. Lins, M. M. P. Zoccoli, T. L. V. Freitas, M. P. D. Camargos, E. F. Psychogeriatrics 2018

aged
article
bacterial infection
Brazil
cerebrovascular accident
Confusion Assessment Method
controlled study
cross-sectional study
delirium
dementia
diagnostic accuracy
diagnostic error
diagnostic test accuracy study
female
gender
hospital emergency service
human
intermethod comparison
major clinical study
male
mental disease assessment
physician
prevalence
priority journal
self concept
sensitivity and specificity
subjective assessment
underdiagnosis

Risk Factors and Hospital Mortality in Surgical and Non-surgical Patients with Delirium. Restrepo, D. Duque, M. Montoya, L. Berrouet, M. C. Rojas, M. Lopera, G. Giraldo, K. Revista Colombiana de Psiquiatria 2018

cholinergic receptor blocking agent
adult
article
cognitive defect
cohort analysis
delirium
descriptive research
female
hospital mortality
hospital patient
human
major clinical study
male
mortality risk
retrospective study
risk assessment
scientific literature
surgical patient

Caring for Critically Ill Patients with the ABCDEF Bundle: Results of the ICU Liberation Collaborative in Over 15,000 Adults. Pun, B. T. Balas, M. C. Barnes-Daly, M. A. Thompson, J. L. Aldrich, J. M. Barr, J. Byrum, D. Carson, S. S. Devlin, J. W. Engel, H. J. Esbrook, C. L. Hargett, K. D. Harmon, L. Hielsberg, C. Jackson, J. C. Kelly, T. L. Kumar, V. Millner, L. Morse, A. Perme, Crit Care Med 2019

adult
article
artificial ventilation
clinical outcome
cohort analysis
coma
controlled study
critically ill patient
death
delirium
dose response
female
hospital discharge
hospital readmission
human
major clinical study
male
mortality
multicenter study
pain
prospective study
total quality management

Effects of Perioperative Dexmedetomidine on Postoperative Mortality and Morbidity: A Systematic Review and Meta-analysis Peng, K. Ji, F. H. Liu, H. Y. Zhang, J. Chen, Q. C. Jiang, Y. H. Clinical Therapeutics 2018

adult
article
artificial ventilation
atrial fibrillation
bradycardia
cohort analysis
complication
controlled study
delirium
drug therapy
Embase
female
heart arrest
heart surgery
hospitalization
human
intensive care unit
male
Medline
morbidity
outcome assessment
prescription
prevalence
randomized controlled trial (topic)
surgery
surgical mortality
systematic review
dexmedetomidine

Relation Between Delirium and Anticholinergic Drug Burden in a Cohort of Hospitalized Older Patients: An Observational Study. Pasina, L. Colzani, L. Cortesi, L. Tettamanti, M. Zambon, A. Nobili, A. Mazzone, A. Mazzola, P. Annoni, G. Bellelli, G. Drugs Aging 2018

adverse event
aged
animal experiment
animal model
animal tissue
anticholinergic effect
article
central nervous system
cohort analysis
controlled study
cross-sectional study
delirium
dementia
diagnosis
dose response
drug combination
drug therapy
drug toxicity
female
Italy
male
malnutrition
multicenter study
nonhuman
nutritional assessment
observational study
retrospective study
risk assessment
sensitivity and specificity
side effect
univariate analysis
cholinergic receptor blocking agent
quetiapine

Neopterin and mini-mental state examination scores, two independent risk factors for postoperative delirium in elderly patients with open abdominal surgery. Miao, S. Shen, P. Zhang, Q. Wang, H. Shen, J. Wang, G. Lv, D. Journal of Cancer Research and Therapeutics 2018

C reactive protein
interleukin 6
neopterin
somatomedin C
abdominal surgery
aged
article
blood sampling
body mass
cancer research
cancer surgery
Charlson Comorbidity Index
comorbidity
comparative study
delirium
DSM-IV
enzyme linked immunosorbent assay
female
gastrointestinal tumor
geriatric patient
human
laparotomy
logistic regression analysis
major clinical study
male
mental health
Mini Mental State Examination
open surgery
postoperative delirium
prediction
risk factor

Reliability and accuracy of delirium assessments among investigators at multiple international centres. Maybrier, H. R. Mickle, A. M. Escallier, K. E. Lin, N. Schmitt, E. M. Upadhyayula, R. T. Wildes, T. S. Mashour, G. A. Palihnich, K. Inouye, S. K. Avidan, M. S. BMJ Open 2018

NCT01690988
aged
article
clinical article
controlled study
delirium
diagnostic accuracy
disease severity
feedback system
female
human
interrater reliability
male
multicenter study
outcome assessment
predictive value
prophylaxis
randomized controlled trial
sensitivity and specificity
videorecording

Does the melatonin receptor 1B gene polymorphism have a role in postoperative delirium? Mahanna-Gabrielli, E. Miano, T. A. Augoustides, J. G. Kim, C. Bavaria, J. E. Andrew Kofke, W. PLoS ONE 2018

adult
aged
aortic root surgery
aortic valve repair
article
controlled study
female
genetic risk
genotype
human
major clinical study
male
melatonin receptor 1B gene
postoperative delirium
receptor gene
single nucleotide polymorphism

Volatile anaesthetics and postoperative delirium in older surgical patients—A secondary analysis of prospective cohort studies Kinjo, S. Lim, E. Magsaysay, M. V. Sands, L. P. Leung, J. M. Acta Anaesthesiol Scand 2019

desflurane
isoflurane
sevoflurane
aged
article
brain function
cognition
cohort analysis
controlled study
drug efficacy
drug safety
female
follow up
human
incidence
major clinical study
male
peripheral nerve
postoperative delirium
postoperative pain
preoperative evaluation
priority journal
prospective study
secondary analysis
surgical patient
surgical risk
very elderly

Addition of Suvorexant to Ramelteon Therapy for Improved Sleep Quality with Reduced Delirium Risk in Acute Stroke Patients. Kawada, K. Ohta, T. Tanaka, K. Miyamura, M. Tanaka, S. Journal of Stroke and Cerebrovascular Diseases 2019

phosphorus 33
ramelteon
suvorexant
zolpidem
aged
article
body mass
brain infarction
cerebrovascular accident
cohort analysis
combination drug therapy
controlled study
daytime somnolence
delirium
disease association
female
hospitalization
human
logistic regression analysis
major clinical study
male
priority journal
retrospective study
risk factor
single blind procedure
sleep disorder
sleep quality

Age-dependent morbidity and mortality outcomes after surgical aortic valve replacement. Hussain, A. I. Auensen, A. Brunborg, C. Beitnes, J. O. Gullestad, L. Pettersen, K. I. Interactive cardiovascular and thoracic surgery 2018

NCT01794832
pacemaker
age
aged
aortic stenosis
aortic valve replacement
article
cause of death
cerebrovascular accident
clinical trial
cognition
cohort analysis
delirium
disease severity
female
hazard ratio
heart failure
heart infarction
hospital readmission
human
infection
length of stay
major clinical study
male
morbidity
mortality rate
mortality risk
New York Heart Association class
postoperative complication
priority journal
prospective study
quality of life
survival
transient ischemic attack
very elderly

Interventions for preventing intensive care unit delirium in adults. Herling, S. F. Greve, I. E. Vasilevskis, E. E. Egerod, I. Bekker Mortensen, C. Møller, A. M. Svenningsen, H. Thomsen, T. Cochrane Database of Systematic Reviews 2018

ISRCTN83567338
NCT00095251
NCT00466492
NCT00675363
NCT00824239
NCT01270269
NCT01274819
NCT01739933
NCT01785290
NCT01791296
NCT0196768
NCT01983800
NCT02245256
NCT02548923
NCT02612948
NCT02615340
NCT02932358
NCT03002701
NCT03095443
NCT03125252
NCT03172897
NCT03215745
dexmedetomidine
haloperidol
lorazepam
placebo
adult
APACHE
artificial ventilation
bradycardia
cognitive defect
cognitive therapy
coma
critically ill patient
delirium
environmental intervention
health care cost
hospital mortality
human
intensive care unit
intention to treat analysis
intervention study
length of stay
nursing intervention
outcome assessment
physiotherapy
priority journal
randomized controlled trial (topic)
review
sedation
seizure
sensitivity analysis
treatment duration
ventilator weaning

Mortality in people with dementia, delirium, and unspecified cognitive impairment in the general hospital: Prospective cohort study of 6,724 patients with 2 years follow-up. Hapca, S. Guthrie, B. Cvoro, V. Bu, F. Rutherford, A. C. Reynish, E. Donnan, P. T. Clinical Epidemiology 2018

aged
cognition assessment
cognitive defect
cohort analysis
comorbidity
controlled study
delirium
dementia
disease association
disease classification
female
follow up
functional status
general hospital
high risk patient
hospital admission
human
major clinical study
male
mortality
physical disease
prospective study
review
risk factor
very elderly

Neurofilament Light in the Serum and Cerebrospinal Fluid of Hip Fracture Patients with Delirium. Halaas, N. B. Blennow, K. Idland, A. V. Wyller, T. B. Ræder, J. Frihagen, F. Staff, A. C. Zetterberg, H. Watne, L. O. Dementia and Geriatric Cognitive Disorders 2018

aged
article
cerebrospinal fluid
controlled study
delirium
dementia
diagnosis
elective surgery
female
hip fracture
human
human tissue
major clinical study
male
neurofilament
preoperative evaluation
surgery
biological marker
endogenous compound

Investigating speech and language impairments in delirium: A preliminary case-control study. Green, S. Reivonen, S. Rutter, L. M. Nouzova, E. Duncan, N. Clarke, C. MacLullich, A. M. J. Tieges, Z. PLoS One 2018

aged
arousal
article
attention test
case control study
clinical article
cognitive defect
comprehension
controlled study
conversation
delirium
dementia
DSM-5
female
grammar
hospital patient
human
language ability
language disability
male
memory test
Richmond Agitation Sedation Scale
semantics
speech and language rehabilitation
speech disorder
task performance
written language

Elevated serum S-100β in patients with septic shock is associated with delirium. Erikson, K. Ala-Kokko, T. I. Koskenkari, J. Liisanantti, J. H. Kamakura, R. Herzig, K. H. Syrjälä, H. Acta Anaesthesiol Scand 2019

interleukin 6
neuron specific enolase
protein S100B
substance P
adult
aged
article
blood sampling
clinical article
controlled study
delirium
female
human
intensive care unit
male
multiple organ failure
observational study
priority journal
prospective study
protein blood level
septic shock
Sequential Organ Failure Assessment Score

A prospective, observational study of cerebrovascular autoregulation and its association with delirium following cardiac surgery. Chan, B. Aneman, A. Anaesthesia 2019

FORESIGHT Elite
IntelliVue MP70 Patient Monitor
patient monitor
analgesic agent
fentanyl
hypertensive factor
inotropic agent
nitroprusside sodium
propofol
adult
aphasia
article
autoregulation
cerebrovascular disease
cognitive defect
cohort analysis
controlled clinical trial
controlled study
delirium
female
heart surgery
human
impaired cerebrovascular autoregulation
intensive care unit
major clinical study
male
mean arterial pressure
near infrared spectroscopy
observational study
oximetry
postoperative complication
prospective study
surgical patient
tissue oxygenation

Dynamic cerebral autoregulation: A marker of post-operative delirium? Caldas, J. R. Panerai, R. B. Bor-Seng-Shu, E. Ferreira, G. S. R. Camara, L. Passos, R. H. de-Lima-Oliveira, M. Galas, F. R. B. G. Almeida, J. P. Nogueira, R. C. Mian, N. Gaiotto, F. A. Robinson, T. G. Hajjar, L. A. Clinical Neurophysiology 2018

NCT02143544
adult
article
autoregulation
blood flow velocity
blood pressure measurement
brain blood flow
cardiopulmonary bypass
coronary artery bypass graft
disease association
disease marker
female
heart surgery
human
major clinical study
male
observational study
postoperative delirium
preoperative period
priority journal
prospective study
surgical risk

The Golden Angels: Effects of trained volunteers on specialling and readmission rates for people with dementia and delirium in rural hospitals. Blair, A. Anderson, K. Bateman, C. International Psychogeriatrics 2018

hearing aid
visual aid
aged
article
clinical effectiveness
controlled clinical trial
controlled study
decubitus
delirium
dementia
drug use
falling
female
health program
hospital admission
hospital readmission
hospital volunteer
human
length of stay
major clinical study
male
medical education
mortality
nutrition
orientation
outcome assessment
patient care
patient safety
physical activity
prospective study
reproducibility
residential care
risk assessment
rural area

The effectiveness of non-pharmacological interventions in reducing the incidence and duration of delirium in critically ill patients: a systematic review and meta-analysis. Bannon, L. McGaughey, J. Verghis, R. Clarke, M. McAuley, D. F. Blackwood, B. Intensive Care Medicine 2018

adult
article
controlled study
critically ill patient
delirium
female
human
incidence
intensive care
male
meta analysis
outcome assessment
phototherapy
physiotherapy
randomized controlled trial (topic)
systematic review
voice

Blood Thiamine Level and Cognitive Function in Older Hospitalized Patients. Pourhassan, M. Angersbach, B. Lueg, G. Klimek, C. N. Wirth, R. J Geriatr Psychiatry Neurol 2018

delirium
dementia
depression
functional status
recovery
thiamine

Low doses of ketamine reduce delirium but not opiate consumption in mechanically ventilated and sedated ICU patients: A randomised double-blind control trial. Perbet, S. Verdonk, F. Godet, T. Jabaudon, M. Chartier, C. Cayot, S. Guerin, R. Morand, D. Bazin, J. E. Futier, E. Pereira, B. Constantin, J. M. Anaesth Crit Care Pain Med 2018

Consumption of opiates
Delirium
Intensive care unit
Ketamine infusion
Mechanical ventilation

CSF sodium at toxic levels precedes delirium in hip fracture patients. Hassel, B. Mariussen, E. Idland, A. V. Dahl, G. T. Raeder, J. Frihagen, F. Berg, J. P. Chaudhry, F. A. Wyller, T. B. Watne, L. O. Neurotoxicology 2018

Cerebrospinal fluid
Choroid plexus
Delirium
Potassium
Serum
Sodium

Relationship between the administration of nicardipine hydrochloride and the development of delirium in patients on mechanical ventilation. Zamami, Y. Kouno, Y. Niimura, T. Chuma, M. Imai, T. Mitsui, M. Koyama, T. Kayano, M. Okada, N. Hamano, H. Goda, M. Imanishi, M. Takechi, K. Horinouchi, Y. Kondo, Y. Yanagawa, H. Kitamura, Y. Sendo, T. Ujike, Y. Ishizawa, K. Pharmazie 2018
Prevalence and risk factors of delirium and subsyndromal delirium in Chinese older adults. Yam, K. K. Shea, Y. F. Chan, T. C. Chiu, K. C. Luk, J. K. Chu, L. W. Chan, F. H. Geriatrics & Gerontology International 2018

Chinese
delirium
prevalence
risk factors
subsyndromal delirium

Home-based Cognitive Prehabilitation in Older Surgical Patients: A Feasibility Study. Vlisides, P. E. Das, A. R. Thompson, A. M. Kunkler, B. Zierau, M. Cantley, M. J. McKinney, A. M. Giordani, B. J Neurosurg Anesthesiol 2018
Meta-analysis of Prevalence and Risk Factors for Delirium After Transcatheter Aortic Valve Implantation. Tilley, E. Psaltis, P. J. Loetscher, T. Davis, D. H. Harrison, S. L. Kim, S. Keage, H. A. D. Am J Cardiol 2018
Development and feasibility of a smartphone-based test for the objective detection and monitoring of attention impairments in delirium in the ICU. Tang, E. Laverty, M. Weir, A. Wilson, E. S. Walsh, T. S. Allerhand, M. Parks, S. MacLullich, A. M. J. Tieges, Z. J Crit Care 2018

Arousal
Attention Impairments
Case-Control Study
Cognitive Assessment
Delirium
Smartphone

Retrospective Analysis of Perioperative Variables Associated With Postoperative Delirium and Other Adverse Outcomes in Older Patients After Spine Surgery. Susano, M. J. Scheetz, S. D. Grasfield, R. H. Cheung, D. Xu, X. Kang, J. D. Smith, T. R. Lu, Y. Groff, M. W. Chi, J. H. Crosby, G. Culley, D. J. J Neurosurg Anesthesiol 2018
Delirium detection by a novel bispectral electroencephalography device in general hospital. Shinozaki, G. Chan, A. C. Sparr, N. A. Zarei, K. Gaul, L. N. Heinzman, J. T. Robles, J. Yuki, K. Chronis, T. J. Ando, T. Wong, T. Sabbagh, S. Weckmann, M. T. Lee, S. Yamada, T. Karam, M. D. Noiseux, N. O. Shinozaki, E. Cromwell, J. W. Psychiatry Clin Neurosci 2018

Aged
Aged, 80 and over
Brain/*physiopathology
Delirium/*diagnosis/physiopathology
Electroencephalography/*methods
Female
Humans
Male
Mass Screening
Middle Aged
Pilot Projects
*Point-of-Care Systems
delirium
electroencephalogram
point of care
power spectral analysis

Incremental cost and length of stay associated with postprocedure delirium in transcatheter and surgical aortic valve replacement patients in the United States. Potter, B. J. Thompson, C. Green, P. Clancy, S. Catheterization and Cardiovascular Interventions 2018

aortic
aortic valve disease
economics/cost-effectiveness
elderly patients
surgery
transcatheter valve implantation

Effect of regional versus general anaesthesia on postoperative delirium in elderly patients undergoing surgery for hip fracture: a systematic review. Patel, V. Champaneria, R. Dretzke, J. Yeung, J. BMJ Open 2018

general anaesthesia
hip fracture
regional anaesthesia
systematic review

The Role of Perioperative Statin Use in the Prevention of Delirium After Total Knee Replacement Under Spinal Anesthesia. Oh, T. K. Park, H. Y. Shin, H. J. Jeon, Y. T. Do, S. H. Hwang, J. W. J Arthroplasty 2018

analgesics
anesthesia
arthroplasty
delirium
hydroxymethylglutaryl coenzyme A reductase inhibitors

Observational Study Examining the Association of Baseline Frailty and Postcardiac Surgery Delirium and Cognitive Change. Nomura, Y. Nakano, M. Bush, B. Tian, J. Yamaguchi, A. Walston, J. Hasan, R. Zehr, K. Mandal, K. LaFlam, A. Neufeld, K. J. Kamath, V. Hogue, C. W. Brown, C. H. th Anesth Analg 2018
CAM-ICU may not be the optimal screening tool for early delirium screening in older emergency department patients: a prospective cohort study. Lucke, J. A. De Gelder, J. Blomaard, L. C. Fogteloo, A. J. Alsma, J. Schuit, S. C. E. Brink, A. De Groot, B. Blauw, G. J. Mooijaart, S. P. Eur J Emerg Med 2018
Relation of postoperative serum S100A12 levels to delirium and cognitive dysfunction occurring after hip fracture surgery in elderly patients. Li, Q. H. Yu, L. Yu, Z. W. Fan, X. L. Yao, W. X. Ji, C. Deng, F. Luo, X. Z. Sun, J. L. Brain Behav 2018

S100a12
cognitive dysfunction
delirium
elderly
hip fracture
postoperative

A scoping review to map empirical evidence regarding key domains and questions in the clinical pathway of delirium in palliative care. Lawlor, P. G. Rutkowski, N. A. MacDonald, A. R. Ansari, M. T. Sikora, L. Momoli, F. Kanji, S. Wright, D. K. Rosenberg, E. Hosie, A. Pereira, J. L. Meagher, D. Rice, J. Scott, J. Bush, S. H. J Pain Symptom Manage 2018

analytic framework
assessment
delirium
management
palliative care
prognosis

Arousal changes and delirium in acute medically-ill male older patients with and without dementia: a prospective study during hospitalization. Lagarto, L. Albuquerque, E. Loureiro, D. Vieira, F. Esteves, P. Neves, S. Teixeira-Verissimo, M. Cerejeira, J. Aging Ment Health 2018

Arousal
delirium
dementia

Incidence and Prevalence of Delirium Subtypes in an Adult ICU: A Systematic Review and Meta-Analysis. Krewulak, K. D. Stelfox, H. T. Leigh, J. P. Ely, E. W. Fiest, K. M. Crit Care Med 2018
Association between death and loss of stage N2 sleep features among critically Ill patients with delirium. Knauert, M. P. Gilmore, E. J. Murphy, T. E. Yaggi, H. K. Van Ness, P. H. Han, L. Hirsch, L. J. Pisani, M. A. J Crit Care 2018

Critical illness
Delirium
Electroencephalography
Encephalopathy
Polysomnography
Sleep

Preventing Postoperative Delirium After Major Noncardiac Thoracic Surgery-A Randomized Clinical Trial. Khan, B. A. Perkins, A. J. Campbell, N. L. Gao, S. Khan, S. H. Wang, S. Fuchita, M. Weber, D. J. Zarzaur, B. L. Boustani, M. A. Kesler, K. J Am Geriatr Soc 2018

Icu
cognition
delirium
esophagectomy
haloperidol

Effect of nonpharmacological interventions for the prevention of delirium in the intensive care unit: A systematic review and meta-analysis. Kang, J. Lee, M. Ko, H. Kim, S. Yun, S. Jeong, Y. Cho, Y. J Crit Care 2018

Delirium
Intensive care unit
Meta-analysis
Nonpharmacological
Prevention

Assessment of Instruments for Measurement of Delirium Severity: A Systematic Review. Jones, R. N. Cizginer, S. Pavlech, L. Albuquerque, A. Daiello, L. A. Dharmarajan, K. Gleason, L. J. Helfand, B. Massimo, L. Oh, E. Okereke, O. I. Tabloski, P. Rabin, L. A. Yue, J. Marcantonio, E. R. Fong, T. G. Hshieh, T. T. Metzger, E. D. Erickson, K. Sc JAMA Intern Med 2018
Nurses' Recognition of Hospitalized Older Patients With Delirium and Cognitive Impairment Using the Delirium Observation Screening Scale: A Prospective Comparison Study. Hasemann, W. Tolson, D. Godwin, J. Spirig, R. Frei, I. A. Kressig, R. W. J Gerontol Nurs 2018
Neurofilament Light in Serum and Cerebrospinal Fluid of Hip Fracture Patients with Delirium. Halaas, N. B. Blennow, K. Idland, A. V. Wyller, T. B. Raeder, J. Frihagen, F. Staff, A. C. Zetterberg, H. Watne, L. O. Dement Geriatr Cogn Disord 2018

*Blood and cerebrospinal fluid biomarker
*Delirium
*Dementia
*Neuroaxonal injury

Delirium Subtypes and Associated Characteristics in Older Patients With Exacerbation of Chronic Conditions. Gual, N. Inzitari, M. Carrizo, G. Calle, A. Udina, C. Yuste, A. Morandi, A. Am J Geriatr Psychiatry 2018

Delirium motor subtypes
functional trajectory
hyperactive delirium
hypoactive delirium
mortality

Antimicrobial exposure and the risk of delirium in critically ill patients. Grahl, J. J. Stollings, J. L. Rakhit, S. Person, A. K. Wang, L. Thompson, J. L. Pandharipande, P. P. Ely, E. W. Patel, M. B. Crit Care 2018

*Antibiotics
*Critical care
*Delirium
*Encephalopathy
*Neurotoxicity

Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness. Girard, T. D. Exline, M. C. Carson, S. S. Hough, C. L. Rock, P. Gong, M. N. Douglas, I. S. Malhotra, A. Owens, R. L. Feinstein, D. J. Khan, B. Pisani, M. A. Hyzy, R. C. Schmidt, G. A. Schweickert, W. D. Hite, R. D. Bowton, D. L. Masica, A. L. Thompson, J. N Engl J Med 2018
A Systematic Review and Meta-Analysis Examining the Impact of Sleep Disturbance on Postoperative Delirium. Fadayomi, A. B. Ibala, R. Bilotta, F. Westover, M. B. Akeju, O. Crit Care Med 2018
Pharmacologic Treatment of Intensive Care Unit Delirium and the Impact on Duration of Delirium, Length of Intensive Care Unit Stay, Length of Hospitalization, and 28-Day Mortality. Daniels, L. M. Nelson, S. B. Frank, R. D. Park, J. G. Mayo Clin Proc 2018
Incidence and clinical significance of postoperative delirium after brain tumor surgery. Budenas, A. Tamasauskas, S. Sliauzys, A. Navickaite, I. Sidaraite, M. Pranckeviciene, A. Deltuva, V. P. Tamasauskas, A. Bunevicius, A. Acta Neurochir (Wien) 2018

Brain tumor
Neurosurgery
Postoperative delirium
Short-term outcomes

Role of perceived stress in postoperative delirium: an investigation among elderly patients. Banjongrewadee, M. Wongpakaran, N. Wongpakaran, T. Pipanmekaporn, T. Punjasawadwong, Y. Mueankwan, S. Aging Ment Health 2018

Perceived stress
delirium
elderly
surgery

Predictors and Sequelae of Postoperative Delirium in Geriatric Hip Fracture Patients. Arshi, A. Lai, W. C. Chen, J. B. Bukata, S. V. Stavrakis, A. I. Zeegen, E. N. Geriatr Orthop Surg Rehabil 2018

delirium
fragility fractures
geriatric trauma
systems of care
trauma surgery
conflicts of interest with respect to the research, authorship, and/or
publication of this article.

Operative and anaesthetic factors influencing on delirium in the intensive care unit: An Analysis of electronic health records. An, Y. S. Jin, Y. Jin, T. Hur, E. Y. Lee, S. M. J Clin Nurs 2018

delirium
electronic health records
intensive care unit
risk factor

Effect of anticholinergic burden on treatment modification, delirium and mortality in newly diagnosed dementia patients starting a cholinesterase inhibitor: a population-based study. Ah, Y. M. Suh, Y. Jun, K. Hwang, S. Lee, J. Y. Basic Clin Pharmacol Toxicol 2018

Alzheimer’s disease
anticholinergics
cholinesterase inhibitors
delirium
mortalitya

Postoperative Delirium in Individuals Undergoing Transcatheter Aortic Valve Replacement: A Systematic Review and Meta-Analysis. Abawi, M. Pagnesi, M. Agostoni, P. Chiarito, M. van Jaarsveld, R. C. van Dongen, C. S. Slooter, A. J. C. Colombo, A. Kooistra, N. H. M. Doevendans, Pafm Latib, A. Stella, P. R. J Am Geriatr Soc 2018

Tavr
cognition
delirium
transcatheter aortic valve replacement

Effect of goal-directed fluid therapy on early cognitive function in elderly patients with spinal stenosis: A Case-Control Study. Zhang, N. Liang, M. Zhang, D. D. Xiao, Y. R. Li, Y. Z. Gao, Y. G. Cai, H. D. Lin, X. Z. Lin, C. Z. Zeng, K. Wu, X. D. Int J Surg 2018

Elderly patients
Goal-directed fluid therapy
Postoperative cognitive dysfunction
Spinal stenosis

Rehospitalization following a stay in geriatric rehabilitation wards: rates and predictive factors. Tardivel, M. Muller, F. Tortrat, D. Lechowski, L. Teillet, L. Geriatr Psychol Neuropsychiatr Vieil 2018

geriatric post-acute and rehabilitation care wards
predictive factors
rehospitalization

Elimination of Routine Benzodiazepine Administration for Nonprocedural Sedation in a Trauma Intensive Care Unit Is Feasible. McGinn, K. Davis, S. N. Terrry, E. Simmons, J. Brevard, S. Am Surg 2018

Adult
Benzodiazepines/*therapeutic use
*Critical Care
Delirium/etiology/*prevention & control
Feasibility Studies
Female
Humans
Hypnotics and Sedatives/*therapeutic use
Injury Severity Score
Male
Psychomotor Agitation/etiology/*prevention & control
Retrospective Studies
Trauma Centers
Wounds and Injuries/*psychology/therapy

Can Chaotic Analysis of Electroencephalogram Aid the Diagnosis of Encephalopathy? Jacob, J. E. Cherian, A. Gopakumar, K. Iype, T. Yohannan, D. G. Divya, K. P. Neurology Research International 2018

adult
article
brain function
case control study
clinical article
clinical feature
clinical indicator
controlled study
diagnostic accuracy
electroencephalogram
electroencephalography
female
human
male
metabolic encephalopathy
randomized controlled trial
retrospective study
support vector machine

Hospital outcomes of older people with cognitive impairment: An integrative review. Fogg, C. Griffiths, P. Meredith, P. Bridges, J. Int J Geriatr Psychiatry 2018

cognitive dysfunction
dementia
integrative review
older people
outcomes
patient admission

Physostigmine is superior to non-antidote therapy in the management of antimuscarinic delirium: a prospective study from a regional poison center. Boley, S. P. Olives, T. D. Bangh, S. A. Fahrner, S. Cole, J. B. Clin Toxicol 2018

Physostigmine
anticholinergic toxidrome
antimuscarinic
delirium
poison center

Cholinesterase inhibitors for the treatment of delirium in non-ICU settings. Yu, A. Wu, S. Zhang, Z. Dening, T. Zhao, S. Pinner, G. Xia, J. Yang, D. Cochrane Database of Systematic Reviews 2018
Perioperative dexmedetomidine reduces delirium after cardiac surgery: A meta-analysis of randomized controlled trials Wu, M. Liang, Y. Dai, Z. Wang, S. J Clin Anesth 2018

Cardiac surgery
Delirium
Dexmedetomidine
Meta-analysis

Diabetes and Glucose Dysregulation and Transition to Delirium in ICU Patients. van Keulen, K. Knol, W. Belitser, S. V. van der Linden, P. D. Heerdink, E. R. Egberts, T. C. G. Slooter, A. J. C. Crit Care Med 2018
Factors associated with delirium in critical patients in a health institution in Bucaramanga, Colombia. Torres-Contreras, C. C. Paez-Esteban, A. N. Hinestrosa-Diaz Del Castillo, A. Rincon-Romero, M. K. Amaris-Vega, A. Martinez-Patino, J. P. Enferm Intensiva 2018

Delirium
Incidence
Incidencia
Intensive Care Unit
Unidad de Cuidados Intensivos

The effect of preoperative cognitive impairment and type of vascular surgery procedure on postoperative delirium with associated cost implications. Styra, R. Larsen, E. Dimas, M. A. Baston, D. Elgie-Watson, J. Flockhart, L. Lindsay, T. F. J Vasc Surg 2018

Cognition
Delirium
MoCA
Preoperative
Vascular surgery

Rate and risk factors for a hyperactivity delirium in patients with aneurysmal subarachnoid haemorrhage. Sauvigny, T. Mohme, M. Grensemann, J. Duhrsen, L. Regelsberger, J. Kluge, S. Schmidt, N. O. Westphal, M. Czorlich, P. Neurosurg Rev 2018

Delirium
Hydrocephalus
Microsurgical clipping
Neurocritical care
Rass
Subarachnoid haemorrhage

Delirium in Postoperative Patients Admitted to the Intensive Care Unit. Romanauski, T. R. Martin, E. E. Sprung, J. Martin, D. P. Schroeder, D. R. Weingarten, T. N. Am Surg 2018

Adult
Aged
Delirium/*epidemiology
Female
Humans
*Intensive Care Units
International Classification of Diseases
Length of Stay
Male
Middle Aged
Postoperative Complications/*epidemiology
Retrospective Studies
Risk Factors
Surgical Procedures, Operative/*adverse effects/statistics & numerical data

Degree of implementation of preventive strategies for post-ICU syndrome: Multi-centre, observational study in Spain. Raurell-Torreda, M. Arias-Rivera, S. Marti, J. D. Frade-Mera, M. J. Zaragoza-Garcia, I. Gallart, E. Velasco-Sanz, T. R. San Jose-Arribas, A. Blazquez-Martinez, E. Enferm Intensiva 2018

Critical illness
Early mobility
Enfermedad critica
Enfermeria
Intensive Care Units
Movilizacion precoz
Nursing
Physical therapy
Rehabilitacion
Rehabilitation
Terapia fisica
Unidades de Cuidados Intensivos

Surgical delay is a risk factor of delirium in hip fracture patients with mild-moderate cognitive impairment. Pioli, G. Bendini, C. Giusti, A. Pignedoli, P. Cappa, M. Iotti, E. Ferri, M. A. Bergonzini, E. Sabetta, E. Aging Clin Exp Res 2018

Delirium
Dementia
Hip fracture
Orthogeriatric
Osteoporosis

Predictors of Delirium Development in Older Medical Inpatients: Readily Identifiable Factors at Admission. O’Regan, Niamh A. Fitzgerald, James Adamis, Dimitrios Molloy, David William Meagher, David Timmons, Suzanne Montero-Odasso, Manuel Journal of Alzheimer's Disease 2018
Processed Electroencephalogram Monitoring and Postoperative Delirium: A Systematic Review and Meta-analysis. MacKenzie, K. K. Britt-Spells, A. M. Sands, L. P. Leung, J. M. Anesthesiology 2018
The influence of oxygen delivery during cardiopulmonary bypass on the incidence of delirium in CABG patients; a retrospective study Leenders, J. Overdevest, E. van Straten, B. Golab, H. Perfusion 2018

Cabg
cardiopulmonary bypass
delirium
oxygen delivery

Safety of brotizolam in hospitalized patients. Lavon, O. Bejel, S. European Journal of Clinical Pharmacology 2018

benzodiazepine derivative
brotizolam
aged
article
artificial ventilation
cohort analysis
comorbidity
controlled study
delirium
drug safety
falling
female
hospital patient
human
insomnia
internal medicine
major clinical study
male
multivariate logistic regression analysis
outcome assessment
prescription
priority journal
respiratory tract disease
retrospective study
risk benefit analysis
risk factor
side effect

Early delirium after cardiac surgery: An analysis of incidence and risk factors in elderly (≥65 years) and very elderly (≥80 years) patients. Kotfis, K. Szylińska, A. Listewnik, M. Strzelbicka, M. Brykczyński, M. Rotter, I. Żukowski, M. Clinical Interventions in Aging 2018

creatinine
age
aged
artery disease
article
atrial fibrillation
clinical outcome
cohort analysis
controlled study
creatinine blood level
delirium
diabetes mellitus
female
heart ejection fraction
heart surgery
hospitalization
human
incidence
intensive care unit
major clinical study
male
mortality rate
pneumonia
postoperative complication
postoperative period
prospective study
retrospective study
risk factor
tertiary care center
very elderly

ICU delirium - a diagnostic and therapeutic challenge in the intensive care unit. Kotfis, K. Marra, A. Ely, E. W. Anaesthesiol Intensive Ther 2018

Cam-icu
Icu
critical care
delirium
monitoring

Melatonin and sleep in preventing hospitalized delirium: A randomized clinical trial. Jaiswal, S. J. McCarthy, T. J. Wineinger, N. E. Kang, D. Y. Song, J. Garcia, S. van Niekerk, C. J. Lu, C. Y. Loeks, M. Owens, R. L. Am J Med 2018

Delirium
Melatonin
Sleep

Intraoperative ketamine administration to prevent delirium or postoperative cognitive dysfunction: A systematic review and meta-analysis. Hovaguimian, F. Tschopp, C. Beck-Schimmer, B. Puhan, M. Acta Anaesthesiol Scand 2018

cognitive dysfunction
ketamine
meta-analysis
postoperative delirium

The use of clonidine in elderly patients with delirium; pharmacokinetics and hemodynamic responses. Hov, K. R. Neerland, B. E. Andersen, A. M. Undseth, O. Wyller, V. B. MacLullich, A. M. J. Skovlund, E. Qvigstad, E. Wyller, T. B. BMC Pharmacol Toxicol 2018

Clonidine
Delirium
Pharmacokinetic
Rct

Delirium's Arousal Subtypes and Their Relationship with 6-Month Functional Status and Cognition. Han, J. H. Hayhurst, C. J. Chandrasekhar, R. Hughes, C. G. Vasilevskis, E. E. Wilson, J. E. Schnelle, J. F. Dittus, R. S. Ely, E. W. Psychosomatics 2018

aged
arousal
article
cognitive defect
cohort analysis
controlled study
daily life activity
emergency ward
female
functional status
hospital patient
hospitalization
human
major clinical study
male
multiple linear regression analysis
prospective study
questionnaire
Richmond Agitation Sedation Scale
secondary analysis

Intraoperative electroencephalogram suppression at lower volatile anaesthetic concentrations predicts postoperative delirium occurring in the intensive care unit. Fritz, B. A. Maybrier, H. R. Avidan, M. S. British Journal of Anaesthesia 2018

NCT02032030
inhalation anesthetic agent
adult
aged
article
bispectral index
cohort analysis
controlled study
elective surgery
electroencephalogram
electroencephalography monitoring
electronic medical record
female
human
incidence
intensive care unit
major clinical study
male
postoperative delirium
prediction
priority journal
retrospective study
risk factor
sleep disordered breathing

Efficacy of perioperative dexmedetomidine on postoperative delirium: systematic review and meta-analysis with trial sequential analysis of randomised controlled trials. Duan, X. Coburn, M. Rossaint, R. Sanders, R. D. Waesberghe, J. V. Kowark, A. British Journal of Anaesthesia 2018

adult
article
bradycardia
Cochrane Library
controlled study
drug efficacy
drug therapy
female
hospital mortality
human
hypotension
incidence
intensive care unit
length of stay
male
Medline
meta analysis
postoperative delirium
postoperative period
randomized controlled trial (topic)
registration
risk assessment
risk factor
sedation
sequential analysis
surgery
surgical patient
systematic review
dexmedetomidine

Long-term sequelae of acute respiratory distress syndrome caused by severe community-acquired pneumonia: Delirium-associated cognitive impairment and post-traumatic stress disorder. Denke, C. Balzer, F. Menk, M. Szur, S. Brosinsky, G. Tafelski, S. Wernecke, K. D. Deja, M. J Int Med Res 2018

Community-acquired pneumonia
analgesia
delirium
health-related quality of life
long-term outcome
post-traumatic stress disorder

A Performing Arts Intervention Improves Cognitive Dysfunction in 50 Hospitalized Older Adults. Danila, M. I. Melnick, J. A. Mudano, A. Flood, K. Booth, K. Kirklin, K. Saag, K. G. Innov Aging 2018

Alternative and complementary medicine/care/therapy
Delirium
Quality of care

Nursing perspectives on the confusion assessment method: a qualitative focus group study. Wong, E. K. Lee, J. Y. Surendran, A. S. Nair, K. Della Maestra, N. Migliarini, M. St Onge, J. A. Patterson, C. J. Age Ageing 2018
Detection and management of hyperactive and hypoactive delirium in older patients during hospitalization: a retrospective cohort study evaluating daily practice. van Velthuijsen, E. L. Zwakhalen, S. M. G. Mulder, W. J. Verhey, F. R. J. Kempen, Gijm Int J Geriatr Psychiatry 2018

care as usual
delirium
management
prevalence
psychomotor subtypes

Glucose variability during delirium in diabetic and non-diabetic intensive care unit patients: A prospective cohort study. van Keulen, K. Knol, W. Belitser, S. V. Zaal, I. J. van der Linden, P. D. Heerdink, E. R. Egberts, T. C. G. Slooter, A. J. C. PLoS One 2018
Evaluating the use of dexmedetomidine for the reduction of delirium: An integrative review. Pavone, K. J. Cacchione, P. Z. Polomano, R. C. Winner, L. Compton, P. Heart Lung 2018

Delirium
Dexmedetomidine
Elderly
Intensive care
Mechanical ventilation
Mortality

Delirium Monitoring in Neurocritically Ill Patients: A Systematic Review. Patel, M. B. Bednarik, J. Lee, P. Shehabi, Y. Salluh, J. I. Slooter, A. J. Klein, K. E. Skrobik, Y. Morandi, A. Spronk, P. E. Naidech, A. M. Pun, B. T. Bozza, F. A. Marra, A. John, S. Pandharipande, P. P. Ely, E. W. Crit Care Med 2018
Poststroke Delirium Clinical Motor Subtypes: The PRospective Observational POLIsh Study (PROPOLIS). Pasinska, P. Kowalska, K. Klimiec, E. Wilk, A. Szyper-Maciejowska, A. Dziedzic, T. Klimkowicz-Mrowiec, A. J Neuropsychiatry Clin Neurosci 2018

Delirium
Delirium subtype
Risk Factors
Stroke and Other Cerebral Vascular Disease (Neuropsychiatric Aspects)

A systematic review of neuroimaging in delirium: predictors, correlates and consequences. Nitchingham A, Kumar V, Shenkin S, Ferguson KJ, Caplan GA International journal of geriatric psychiatry 2017

delirium
neuroimaging