Delirium Bibliography

Delirium Bibliography books graphicWhat is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!

How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.

Reference Information

Postoperative delirium in 47 379 individuals undergoing transcatheter aortic valve replacement: a systematic review and meta-analysis
Ochani, S. Adnan, A. Siddiqui, A. Kalwar, A. Kukreja, S. Ahmad, M. Ashraf, M. H. Asghar, M. A.
Ann Med Surg (Lond)

OBJECTIVE: The study aims to discuss the assessment methods used for the incidence of in-hospital postoperative delirium (IHPOD) in transcatheter aortic valve replacement (TAVR) patients and explore possible strategies for preventing and reducing postoperative complications in the geriatric population. METHODOLOGY: An electronic search of PubMed, Embase, BioMedCentral, Google Scholar, and the Cochrane Central Register of Controlled Trials was conducted up to August 2021, to identify studies on the IHPOD following TAVR in patients above 70 years. The primary objective of the study was to determine the incidence of delirium following TAVR and procedures like transfemoral (TF) and non-TF approaches. The secondary objectives were to determine the incidence of stroke and incidence according to the confusion assessment method (CAM) diagnostic tool. The authors only included studies published in English and excluded patients with comorbidities and studies with inaccessible full-text. RESULTS: Among the selected 42 studies with 47 379 patients, the incidence of IHPOD following TAVR was 10.5% (95% CI: 9.2-11.9%, I(2)=95.82%, P<0.001). Incidence based on CAM was 15.6% (95% CI: 10.5-20.7%, I(2)=95.36%, P<0.001). The incidence of IHPOD after TF-TAVR was 9.3% (95% CI: 7.6-11.0%, I(2)=94.52%, P<0.001), and after non-TF TAVI was 25.3% (95% CI: 15.4-35.1%, I(2)=92.45%, P<0.001). The incidence of stroke was 3.7% (95% CI: 2.9-4.5%, I(2)=89.76%, P<0.001). Meta-regression analyses between mean age (P=0.146), logistic EuroSCORE (P=0.099), or percentage of participants treated using the TF approach (P=0.276) were nonsignificant while stroke (P=0.010) was significant. When considering these variables, the residual heterogeneity remained high indicating that other variables influence the heterogeneity. CONCLUSION: IHPOD following TAVR was observed in 10.5% of individuals and in 15.6% using CAM. Its incidence was found to be three times higher after non-TF TAVR (25.3%) compared to TF TAVR (9.3%). Stroke showed an incidence of 3.7% after TAVR and was found to be significantly associated with the risk of developing delirium following TAVR. Further studies are needed to evaluate possible causes and risk factors responsible for delirium and to assess the role of anesthesia and cerebral embolic protection in preventing delirium after TAVR.




Cam, Tavr, confusion assessment method, delirium, stroke, transcatheter aortic valve replacement


Total Records Found: 5897, showing 100 per page
Incidence of Postoperative Delirium in Cancer Patients After Head and Neck Surgery: A Proportional Meta-analysis Ho, M. H. Li, P. W. C. Lin, Y. K. Lee, J. J. Lin, C. C. Otolaryngol Head Neck Surg 2023

cancer, delirium, head and neck cancer, incidence, postoperative, proportional Meta-analysis

Triglyceride-glucose index as a valuable predictor for aged 65-years and above in critical delirium patients: evidence from a multi-center study Huang, X. Cheng, H. Yuan, S. Ling, Y. Tan, S. Tang, Y. Niu, C. Lyu, J. BMC Geriatr 2023

*Critical Care
Databases, Factual
Blood Glucose
Risk Factors
Critical care
Insulin resistance
Older adults
Triglyceride glucose index

Reliability and Validity of the Spanish Adaptation of the Stanford Proxy Test for Delirium in 2 Clinical Spanish-Speaking Communities Infante, S. Behn, A. González, M. Pintor, L. Franco, E. Araya, P. Maldonado, J. R. J Acad Consult Liaison Psychiatry 2023

Stanford proxy test for delirium, confusion assessment method, delirium, delirium and COVID, factor analysis

Association between preoperative neutrophil-lymphocyte ratio, uric acid, and postoperative delirium in elderly patients undergoing degenerative spine surgery Kato, K. Kinoshita, H. Kumagai, G. Takekawa, D. Nitobe, Y. Asari, T. Wada, K. Kushikata, T. Ishibashi, Y. Hirota, K. J Anesth 2023

Neuroprotection, Neutrophil–lymphocyte ratio, Postoperative delirium, Spine surgery, Uric acid

Preoperative assessment of postoperative delirium: a cross-sectional study of patients and anesthesiologists in Canada Khaled, M. Youssef, N. Choi, S. Uppal, V. Chui, J. Marcucci, M. Madden, K. Shanthanna, H. Can J Anaesth 2023

*Emergence Delirium
Cross-Sectional Studies
Risk Factors
Postoperative Complications/etiology
older adults
postoperative delirium
preoperative screening
risk reduction
shared decision-making

Resting-state prefrontal EEG biomarker in correlation with postoperative delirium in elderly patients Kim, J. Park, S. Kim, K. N. Ha, Y. Shin, S. J. Cha, W. Lee, K. Y. Choi, J. Koo, B. N. Front Aging Neurosci 2023

elderly, electroencephalography, median dominant frequency, postoperative complications, postoperative delirium

Risk of delirium with antiepileptic drug use: a study based on the Japanese Adverse Drug Event Report database Kubo, T. Sogawa, R. Tsuruhashi, S. Murakawa-Hirachi, T. Matsuoka, A. Mizoguchi, Y. Monji, A. Shimanoe, C. Int J Clin Pharm 2023

Anticonvulsants/adverse effects
Receptors, GABA-A
East Asian People
*Drug-Related Side Effects and Adverse Reactions
*Delirium/chemically induced/epidemiology/drug therapy
Adverse event
Antiepileptic drugs

Optimizing delirium care in the era of Age-Friendly Health System Kwak, M. J. Inouye, S. K. Fick, D. M. Bonner, A. Fulmer, T. Carter, E. Tabbush, V. Maya, K. Reed, N. Waszynski, C. Oh, E. S. J Am Geriatr Soc 2023

Age-Friendly Health System, Hospital Elder Life Program, delirium

Risk factors for hyperactive delirium after laparoscopic radical gastrectomy under general anesthesia in patients with gastric cancer Liu, J. Zhong, Q. Tan, H. Zhuo, M. Zhong, M. Cai, T. Am J Transl Res 2023

Laparoscopic radical gastrectomy, general anesthesia, hyperactive delirium, risk factors

Risk factors associated with postoperative delirium in elderly patients undergoing hip surgery Liu, X. H. Zhang, Q. F. Liu, Y. Lu, Q. W. Wu, J. H. Gao, X. H. Chen, Z. Y. Front Psychiatry 2023

elderly retrospective study
hip surgery
postoperative delirium

The influence of delirium on mortality and length of ICU stay and analysis of risk factors for delirium after liver transplantation Ma, Y. Li, C. Peng, W. Wan, Q. ATS Sch 2023

ICU stay
liver transplantation
risk factors

Hyperactive delirium during emergency department stay: analysis of risk factors and association with short-term outcomes Miró, Ò Osorio, G. Alquézar-Arbé, A. Aguiló, S. Fernández, C. Burillo, G. Jacob, J. Llorens, P. Llauger, L. Peláez González, Á Figuera Castro, E. R. Juarez González, R. Blanco Hoffman, M. J. Fernandez Salgado, F. Pablos Pizarro, T. Berenguer Dí Intern Emerg Med 2023

Benzodiazepines, Delirium, Emergency department, Mortality, Neuroleptics, Outcome

Delirium and neuropsychological recovery among emergency general surgery survivors (DANE): study protocol for a randomized controlled trial and collaborative care intervention Mohanty, S. Holler, E. Ortiz, D. Meagher, A. Perkins, A. Bylund, P. Khan, B. Unverzagt, F. Xu, H. Ingraham, A. Boustani, M. Zarzaur, B. Trials 2023

Treatment Outcome
Randomized Controlled Trials as Topic
Multicenter Studies as Topic
Emergency general surgery
Postoperative delirium

A randomized, clinical trial investigating the use of a digital intervention to reduce delirium-associated agitation Nicholas, M. Wittmann, J. Norena, M. Ornowska, M. Reynolds, S. NPJ Digit Med 2023

delirium, agitation, digital, RASS

Cognitive Deficits in Executive and Language Functions Predict Postoperative Delirium Olotu, C. Lebherz, L. Ascone, L. Scherwath, A. Kühn, S. Härter, M. Kiefmann, R. J Cardiothorac Vasc Anesth 2023

*Emergence Delirium/diagnosis/epidemiology/etiology
Postoperative Complications/diagnosis/epidemiology/etiology
Prospective Studies
*Cognitive Dysfunction/diagnosis/epidemiology/etiology
Risk Factors
neurocognitive disorders
older adults
postoperative delirium
preoperative assessment

Development of post-anesthesia care unit delirium is associated with differences in aperiodic and periodic alpha parameters of the EEG during emergence from general anesthesia - results from a prospective observational cohort study Ostertag, J. Engelhard, A. Nuttall, R. Aydin, D. Schneider, G. García, P. S. Hinzmann, D. Sleigh, J. W. Kratzer, S. Kreuzer, M. Anesthesiology 2023

PACU, delirium, EEG, hypnosis, alpha

Subsyndromal Delirium in Critically Ill Patients-Cognitive and Functional Long-Term Outcomes Paulino, M. C. Conceição, C. Silvestre, J. Lopes, M. I. Gonçalves, H. Dias, C. C. Serafim, R. Salluh, J. I. F. Póvoa, P. J Clin Med 2023

Icu, cognitive dysfunction delirium, long-term outcome, subsyndromal delirium

Prevalence of delirium in gastroenterology/hepatology units: A cross-sectional study Pazouki, R. Hasselblatt, P. Kugler, C. Z Gastroenterol 2023

Middle Aged
Cross-Sectional Studies
*Liver Cirrhosis/complications
Aged, 80 and over
*Hepatic Encephalopathy/complications

Grip Strength is a Predictor for Subsyndromal Delirium Among Older Adults Following Joint Replacement Qian, J. Shen, X. Gao, X. Sun, Q. Clin Interv Aging 2023

*Arthroplasty, Replacement
*Emergence Delirium
Postoperative Complications/diagnosis/epidemiology/etiology
Risk Factors
*Hand Strength
grip strength
joint replacement
risk factor
subsyndromal delirium

Prevalence and Risk Factors of Delirium in Patients Admitted to Intensive Care Units: A Multicentric Cross-Sectional Study Sadaf, F. Saqib, M. Iftikhar, M. Ahmad, A. Cureus 2023

critical illness, delirium, intensive care units, pakistan, prevalence

Perioperative Factors Associated With Postoperative Delirium in Patients Undergoing Noncardiac Surgery: An Individual Patient Data Meta-Analysis Sadeghirad, B. Dodsworth, B. T. Schmutz Gelsomino, N. Goettel, N. Spence, J. Buchan, T. A. Crandon, H. N. Baneshi, M. R. Pol, R. A. Brattinga, B. Park, U. J. Terashima, M. Banning, L. B. D. Van Leeuwen, B. L. Neerland, B. E. Chuan, A. Martinez, F. T. Van JAMA Netw Open 2023

*Emergence Delirium/epidemiology/etiology
Postoperative Complications/epidemiology/etiology/diagnosis
Risk Factors

Thirty-day mortality among patients with acute delirium in the emergency department Sanguanwit, P. Ninlamal, S. Prachanukool, T. Heliyon 2023

30-Day mortality, Delirium, Emergency department, Older-patients

Role of hypoxia-inducible factor in postoperative delirium of aged patients: A review Shen, H. Yang, J. Chen, X. Gao, Y. He, B. Medicine (Baltimore) 2023

Infant, Newborn, Humans, Aged, *Emergence Delirium, Transcription Factors/metabolism, Hypoxia, Ischemia, *Anesthetics, Hypoxia-Inducible Factor 1, alpha Subunit

The efficacy of earplugs and eye masks for delirium severity and sleep quality in patients undergoing coronary artery bypass grafting in cardiac intensive care units: A single-blind, randomised controlled trial Shorofi, S. A. Dadashian, P. Arbon, P. Moosazadeh, M. Aust Crit Care 2023

Coronary artery bypass grafting, Delirium, Earplugs, Eye masks, ICU psychosis, Sleep quality

Efficacy of haloperidol to decrease the burden of delirium in adult critically ill patients: the EuRIDICE randomized clinical trial Smit, L. Slooter, A. J. C. Devlin, J. W. Trogrlic, Z. Hunfeld, N. G. M. Osse, R. J. Ponssen, H. H. Brouwers, Ajbw Schoonderbeek, J. F. Simons, K. S. van den Boogaard, M. Lens, J. A. Boer, D. P. Gommers, Dampj Rietdijk, W. J. R. van der Jagt, M. Crit Care 2023

Middle Aged
*Antipsychotic Agents/adverse effects
Critical Illness/therapy
Intensive Care Units
Quality of Life
Critical care
Randomized controlled trial

Efficacy of haloperidol to decrease the burden of delirium in adult critically ill patients: the EuRIDICE randomized clinical trial Smit, L. Slooter, A. J. C. Devlin, J. W. Trogrlic, Z. Hunfeld, N. G. M. Osse, R. J. Ponssen, H. H. Brouwers, Ajbw Schoonderbeek, J. F. Simons, K. S. van den Boogaard, M. Lens, J. A. Boer, D. P. Gommers, Dampj Rietdijk, W. J. R. van der Jagt, M. Crit Care 2023

Middle Aged
*Antipsychotic Agents/adverse effects
Critical Illness/therapy
Intensive Care Units
Quality of Life
Critical care
Randomized controlled trial

Effectiveness of a Multi-component Delirium Prevention Program Implemented on General Medicine Hospital Units: an Interrupted Time Series Analysis Versloot, J. Minotti, S. C. Amer, S. Ali, A. Ma, J. Peters, M. L. Saab, H. Tang, T. Kerr, J. Reid, R. J Gen Intern Med 2023

Adult, Humans, Aged, Aged, 80 and over, Interrupted Time Series Analysis, Retrospective Studies, *Delirium/diagnosis/epidemiology/prevention & control, Hospitals, Community, Ontario, Hospital Units, delirium prevention, delirium program, inpatients, internal medicine

Delirium During Critical Illness and Subsequent Change of Treatment in Patients With Cancer: A Mediation Analysis Vizzacchi, B. A. Dettino, A. L. A. Besen, Bamp Caruso, P. Nassar, A. P., Jr. Crit Care Med 2023

IUC, delirium, cohort, cancer, CAM

Efficacy and moderators of prevention and treatment of delirium with melatonin receptor agonists: A systematic review and meta-analysis of randomized controlled trials Wada, M. Yasuda, H. Nakajima, S. Etani, T. Miura, A. Asada, S. Yoshida, K. Noda, Y. Takeuchi, H. Gen Hosp Psychiatry 2023

Melatonin receptor agonists

Intraoperative body temperature and emergence delirium in elderly patients after non-cardiac surgery: A secondary analysis of a prospective observational study Wang, G. He, S. Yu, M. Zhang, Y. Mu, D. Wang, D. Chin Med J (Engl) 2023

Body Temperature
*Emergence Delirium
Postoperative Complications/epidemiology
Prospective Studies

Relationship between preoperative neutrophil-to-lymphocyte ratio and postoperative delirium: The PNDABLE and the PNDRFAP cohort studies Wu, X. Chi, F. Wang, B. Liu, S. Wang, F. Wang, J. Tang, X. Bi, Y. Lin, X. Li, J. Brain Behav 2023

Alzheimer-related biomarkers
risk factor

Risk Factors for Delirium Superimposed on Dementia in Elderly Patients in Comprehensive Ward Xiao, Q. Zhang, S. Li, C. Zhu, Y. Am J Alzheimers Dis Other Demen 2023

Retrospective Studies
*Alzheimer Disease/complications
Risk Factors
*Diabetes Mellitus
*Cerebrovascular Disorders
Superoxide Dismutase
Hypnotics and Sedatives
risk factor
senile dementia

Effect of postoperative delirium after cardiovascular surgery on 5-year mortality Yokoyama, C. Yoshitnai, K. Ogata, S. Fukushima, S. Matsuda, H. JA Clin Rep 2023

5-year mortality, Cardiopulmonary bypass, Cardiovascular surgery, Postoperative delirium

Association Between the Use of Midazolam During Cardiac Anesthesia and the Incidence of Postoperative Delirium: A Retrospective Cohort Study Using a Nationwide Database Yoshimura, M. Hidaka, Y. Morimoto, Y. J Cardiothorac Vasc Anesth 2023

Humans, *Emergence Delirium/epidemiology, Midazolam/adverse effects, Retrospective Studies, Incidence, Postoperative Nausea and, Vomiting/chemically induced/epidemiology, *Anesthesia, Cardiac Procedures, Postoperative, Complications/chemically induced/epidemiology, Diagnosis Procedure, Combination data, cardiac surgery, midazolam, postoperative delirium, stabilized inverse probability of treatment

Associations of Delirium to Posthospital Outcomes After Acute Stroke: A Scoping Review Young, B. C. Rhoten, B. A. J Neurosci Nurs 2023

Adult, Humans, Adolescent, *Dexmedetomidine/therapeutic use, Palliative Care, *Pain, Intractable/drug therapy/chemically induced, Hypnotics and, Sedatives/therapeutic use, Retrospective Studies, *Delirium/drug therapy, Intensive Care Units

Dexmedetomidine use for patients in palliative care with intractable pain and delirium: A retrospective study Yu, S. Y. Schellenberg, J. Alleyne, A. PLoS One 2023

Adult, Humans, Adolescent, *Dexmedetomidine/therapeutic use, Palliative Care, *Pain, Intractable/drug therapy/chemically induced, Hypnotics and, Sedatives/therapeutic use, Retrospective Studies, *Delirium/drug therapy, Intensive Care Units

Validity and predictability of the confusion assessment method for the intensive care unit for delirium among critically ill patients in the intensive care unit: A systematic review and meta-analysis Zhang, Y. Diao, D. Zhang, H. Gao, Y. Nurs Crit Care 2023

Cam-icu, critical, delirium, intensive care unit

Impact of nursing interventions on discharge disposition in patients with postoperative delirium Zhao, Y. Quon, A. Luke, K. Tivis, L. J. Nursing 2023

Humans, Aged, Patient Discharge, Retrospective Studies, *Emergence Delirium, *Hypoalbuminemia, Hospitalization

Causal relationships between delirium and Alzheimer's disease: a bidirectional two-sample Mendelian randomization study Zheng, J. Du, X. Yang, L. Fu, H. Eur J Med Res 2023

Humans, *Alzheimer Disease/genetics, Genome-Wide Association Study, Mendelian Randomization Analysis, Risk Factors, Nonoxynol, Alzheimer’s disease, Causal relationships, Delirium, European, Mendelian randomization

Circadian rhythm disturbance and delirium in ICU patients: a prospective cohort study Li, J. Cai, S. Liu, X. Mei, J. Pan, W. Zhong, M. Zhang, Y. Medicine (Baltimore) 2023

United States, Humans, *Hydrocortisone, *Melatonin, Prospective Studies, Circadian Rhythm, Intensive Care Units, Cortisol, Delirium, Melatonin

Amantadine-associated delirium in patients with maintenance dialysis: Insomnia-associated recovery and uneven seasonal distribution Li, J. Si, B. Chao, J. He, J. Medicine (Baltimore) 2023

Humans, Renal Dialysis, Retrospective Studies, Seasons, *Sleep Initiation and Maintenance Disorders/drug therapy, Amantadine/adverse effects, *Delirium/chemically induced/epidemiology

Effects of Different Injection Rates of Propofol on Postoperative Cognition in Elderly Patients Undergoing Laparoscopic Inguinal Hernia Repair Li, T. Han, W. Yang, X. Wang, Y. Peng, L. He, L. Hu, L. Liu, J. Xia, M. Wang, S. Drug Des Devel Ther 2023

Humans, Aged, *Propofol/adverse effects, Anesthetics, Intravenous/adverse effects, *Hernia, Inguinal/surgery/chemically induced, Postoperative, Complications/epidemiology, Cognition, *Delirium, *Laparoscopy, bispectral index, burst suppression, elderly, injection rate, postoperative cognitive decline, propofol

The Effect of Music as a Non-Pharmacological Intervention on the Physiological, Psychological, and Social Response of Patients in an Intensive Care Unit Lorek, M. Bąk, D. Kwiecień-Jaguś, K. Mędrzycka-Dąbrowska, W. Healthcare (Basel) 2023

classical music, delirium, intensive care unit, music perception, music therapy, nursing, pain, therapeutic music listening

Feasibility of a Modified Otago Exercise Program for Older Adults With Cognitive Vulnerability Mangione, K. K. Darreff, H. Welsh, M. Ni, W. Wolff, E. Booth, J. T. Glenney, S. S. Fortinsky, R. H. J Appl Gerontol 2023

Humans, Aged, Exercise Therapy, Feasibility Studies, Postural Balance, *Dementia/therapy, Cognition, *Delirium, Otago exercise program, dementia, depression, exercise, feasibility, older adult

Accuracy of Delirium Screening Tools in Older People with Cancer-A Systematic Review Martínez-Arnau, F. M. Puchades-García, A. Pérez-Ros, P. Cancers (Basel) 2023

accuracy, aged, assessment, cancer, delirium, incidence, prevalence, psychometric properties

Evaluation of the delirium preventive effect of dual orexin receptor antagonist (DORA) in critically ill adult patients requiring ventilation with tracheal intubation at an advanced emergency center: A single-center, retrospective, observational study Matsuoka, A. Sogawa, R. Murakawa-Hirachi, T. Mizoguchi, Y. Monji, A. Shimanoe, C. Shinada, K. Koami, H. Sakamoto, Y. J Alzheimers Dis 2023

Humans, Adult, Adolescent, *Orexin Receptor Antagonists/adverse effects, Retrospective Studies, Critical Illness/therapy, *Delirium/prevention & control/epidemiology, Intubation, Intratracheal, Delirium, Intensive care unit, Lemborexant, Sleep disorder, Suvorexant

Individualized Summary Assessment of Detailed Neuropsychological Testing for the Etiological Diagnosis of Newly Detected Cognitive Impairment in Hospitalized Geriatric Patients Mäurer, A. Himmel, G. Lange, C. Mathies, F. Apostolova, I. Peters, O. Buchert, R. J Alzheimers Dis 2023

Alzheimer’s disease, delirium, dementia, etiological diagnosis, hospitalized, geriatric patients, neuropsychological testing

A systematic review of studies reporting on neuropsychological and functional domains used for assessment of recovery from delirium in acute hospital patients McCartney, H. Noble, E. MacLullich, A. M. J. Davis, D. H. J. Evans, J. Shenkin, S. D. Muniz-Terrera, G. Sandeman, D. Tieges, Z. Int J Geriatr Psychiatry 2023

Humans, *Activities of Daily Living, *Delirium/diagnosis/drug therapy
Hospitals, 4at, delirium assessment, delirium recovery, functional recovery, longitudinal studies, neuropsychological domains, repeat assessment

Implementing a ward-based programme to improve care for older inpatients: process evaluation of the cluster randomised CHERISH trial Mudge, A. M. McRae, P. Young, A. Blackberry, I. Lee-Steere, K. Barrimore, S. Quirke, T. Harvey, G. BMC Health Serv Res 2023

Aged, Humans, *Delirium/prevention & control, Hospitals, *Inpatients, Nutritional Status, Prospective Studies, Age-friendly hospitals, Delirium, Evaluation, Facilitation, Implementation

Effect of laparoscopic liver resection on postoperative delirium in elderly patients with hepatocellular carcinoma Nomi, T. Kaibori, M. Hirokawa, F. Ueno, M. Hokuto, D. Noda, T. Nakai, T. Ikoma, H. Iida, H. Kubo, S. J Hepatobiliary Pancreat Sci 2023

elderly patients, hepatocellular carcinoma, laparoscopic liver resection, postoperative delirium

Development of a scale measuring the difficulties faced by nurses who care for patients with delirium in intensive care units Owaki, N. Tanaka, M. Kawakami, A. Aust Crit Care 2023

Humans, Reproducibility of Results, Pilot Projects, Intensive Care Units, Surveys and Questionnaires, *Delirium, *Nurses, Psychometrics/methods, Delirium, Exploratory factor analysis, Nurse, Psychological distress, Scale development

Preliminary evaluation of a smartphone application (DelApp) for identification of delirium in sub-Saharan Africa Paddick, S. M. Gamassa, E. Mwaluwinga, N. Lewis, G. Duinmaijer, A. Urasa, S. Tucker, L. Mukaetova-Ladinska, E. B. Cosker, G. Dekker, M. Kisoli, A. Cletus, J. Lissu, C. Dotchin, C. Gray, W. K. Walker, R. Acta Neuropsychiatr 2023

Africa, cognitive assessment, delirium, screening

Postoperative delirium after cholecystectomy in older patients: A retrospective study Park, Y. M. Seo, H. I. Noh, B. G. Kim, S. Hong, S. B. Lee, N. K. Kim, D. U. Han, S. Y. Ann Hepatobiliary Pancreat Surg 2023

Body mass index, Cholecystectomy, Delirium, Nutrition, Older patients

Exploring the Documentation of Delirium in Patients After Cardiac Surgery: A Retrospective Patient Record Study Poikajärvi, S. Peltonen, L. M. Siirala, E. Heimonen, J. Moen, H. Salanterä, S. Junttila, K. Comput Inform Nurs 2023

delirium, cardiac, surgery, EHR, documentation

The Efficacy of Low-Dose Risperidone Treatment for Post-Surgical Delirium in Elderly Orthopedic Patients Raphael, L. Edna, E. Irina, K. Oded, H. Medicina (Kaunas) 2023

Female, Humans, Aged, Aged, 80 and over, Male, Risperidone/adverse effects, Prospective Studies, *Delirium/drug therapy/etiology/diagnosis, *Orthopedics, Postoperative Complications/drug therapy, delirium, elderly, post-surgical, protocol, risperidone

Serum Biomarkers of a Pro-Neuroinflammatory State May Define the Pre-Operative Risk for Postoperative Delirium in Spine Surgery Ruhnau, J. Müller, J. Nowak, S. Strack, S. Sperlich, D. Pohl, A. Dilz, J. Saar, A. Veser, Y. Behr, F. Rehberg, S. Usichenko, T. Hahnenkamp, K. Ehler, J. Flöel, A. Schroeder, H. W. S. Müller, J. U. Fleischmann, R. Vogelgesang, A. Int J Mol Sci 2023

Humans, Aged, *Emergence Delirium, Interleukin-6/metabolism, *Delirium/diagnosis/etiology, Gasdermins, Postoperative, Complications/etiology, Prospective Studies, Biomarkers/metabolism, Gasdermin D, biomarker, postoperative cognitive dysfunction, postoperative delirium, sTREM2, spine surgery

Effects of an interactive handgrip game on surgical patients requiring intensive care: An assessor-blinded randomized controlled trial Han, P. H. Shih, C. Y. Wang, A. Y. Chen, Y. C. Yang, C. C. Fan, Y. C. Hsiang, H. F. Chiu, H. Y. Intensive Crit Care Nurs 2023

Critically ill patients, Handgrip strength, Interactive handgrip game, Psychological distress

A critical appraisal and recommendation synthesis of delirium clinical practice guidelines relevant to the care of older adults in the emergency department: An umbrella review Filiatreault, S. Grimshaw, J. M. Kreindler, S. A. Chochinov, A. Linton, J. Chatterjee, R. Azeez, R. Doupe, M. B. J Eval Clin Pract 2023

Agree, aged, delirium, emergency services (hospital), practice guideline, systematic review

Implementation of a novel nursing assessment tool in geriatric trauma patients with proximal femur fractures Berk, T. Thalmann, M. Jensen, K. O. Schwarzenberg, P. Jukema, G. N. Pape, H. C. Halvachizadeh, S. PLoS One 2023

Humans, Aged, Retrospective Studies, *Proximal Femoral Fractures, *Delirium/etiology/complications, Risk Factors, Nutritional Status, Geriatric Assessment

Enhanced recovery after surgery in patients with normal pressure hydrocephalus undergoing ventriculoperitoneal shunting procedures Ali, A. Gupta, B. Johansen, P. Santiago, R. B. Dabecco, R. Mandel, M. Adada, B. Botero, J. Roy, M. Borghei-Razavi, H. Clin Neurol Neurosurg 2023

Humans, Ventriculoperitoneal Shunt/adverse effects, *Hydrocephalus, Normal Pressure/surgery/complications, *Enhanced Recovery After Surgery, Postoperative Complications/etiology, *Delirium/complications/surgery, Length of Stay, Retrospective Studies, Delirium, Eras, Neurosurgery, Normal pressure hydrocephalus, Ventriculoperitoneal shunting

The use of patient sitters at a Swiss hospital: A retrospective observational study Kramer, I. Schubert, M. PLoS One 2023

Aged, Humans, Confusion, *Ethnicity, Hospitals, *Inpatients, Retrospective Studies, Switzerland, Aged, 80 and over

The role of inflammatory parameters in the prediction of postoperative delirium in patients undergoing coronary artery bypass grafting Şaşkin, H. Özcan, K. S. Yildirim, S. Cardiovasc J Afr 2023

Humans, *Emergence Delirium/etiology, Retrospective Studies, Postoperative Complications/diagnosis/etiology, Coronary Artery Bypass/adverse effects, Risk Factors, coronary artery bypass grafting surgery, delirium, inflammation

Opioids increase the risk of delirium in critically ill patients: A propensity score analysis Shi, H. J. Zhang, X. P. Hai, C. Shi, W. Wang, P. Hu, A. M. Int J Clin Pharmacol Ther 2023

Humans, *Analgesics, Opioid/adverse effects, Intensive Care Units, Critical, Illness/therapy, Propensity Score, Risk Factors, *Delirium/chemically induced/diagnosis/epidemiology

Characteristics of delirium and its association with sedation and in-hospital mortality in patients with COVID-19 on veno-venous extracorporeal membrane oxygenation Sun, P. Y. Fanning, J. Peeler, A. Shou, B. Lindsley, J. Caturegli, G. Whitman, G. Cha, S. Kim, B. S. Cho, S. M. Front Med (Lausanne) 2023

analgesia, deep sedation, delirium, extracorporeal membrane oxygenation, hospital mortality

Delirium as a Risk Factor for Mortality in Critically Ill Patients With Cancer Tao, J. Seier, K. Marasigan-Stone, C. B. Simondac, J. S. Pascual, A. V. Kostelecky, N. T. SantaTeresa, E. Nwogugu, S. O. Yang, J. J. Schmeltz, J. Tan, K. S. Chawla, S. Voigt, L. P. JCO Oncol Pract 2023

Humans, Female, Middle Aged, Aged, Male, *Delirium/diagnosis/prevention & control, Critical Illness, Risk Factors, Intensive Care Units, *Neoplasms

Effectiveness of sleep interventions to reduce delirium in critically ill patients: A systematic review and meta-analysis Teng, J. Qin, H. Guo, W. Liu, J. Sun, J. Zhang, Z. J Crit Care 2023

Critical illness, Delirium, ICUs, Meta-analysis, Sleep

Chlorpromazine's Potential Role in Palliating Distressing Symptoms Associated With Hyperactive Delirium in Patients at End of Life Tiefenthaler, C. M. Hirst, J. M. Edmonds, K. P. Atayee, R. S. J Palliat Med 2023

Humans, Chlorpromazine/therapeutic use, Psychomotor Agitation/drug therapy/complications/prevention & control, *Delirium/drug therapy, *Neoplasms/complications, Death, Palliative Care, chlorpromazine
end of life, hyperactive delirium, proportionate sedation

Delirium and IL-6 added to clinical scores improves their performance: a prospective analysis of CALL, PREDI-CO, MRS score applied to a population of patients admitted to internal medicine ward Vannucchi, V. Pelagatti, L. Barone, F. Bertini, L. Celli, T. Boccia, N. Veneziani, F. Cimolato, B. Landini, G. Intern Emerg Med 2023

Call, Covid-19, Delirium,il-6, Mrs, Outcome, Predi-co, Score

Electroencephalographic Biomarkers, Cerebral Oximetry, and Postoperative Cognitive Function in Adult Non-Cardiac Surgical Patients: a Prospective Cohort Study Vlisides, P. E. Li, D. Maywood, M. Zierau, M. Lapointe, A. P. Brooks, J. McKinney, A. M. Leis, A. M. Mentz, G. Mashour, G. A. Anesthesiology 2023

Adult, Humans, Retrospective Studies, Prospective Studies, *Delirium/diagnosis/epidemiology/etiology, Critical Illness, Intensive Care Units, Critically ill, Delirium, Intensive care unit, Machine learning, Prediction

Early prediction of delirium upon intensive care unit admission: Model development, validation, and deployment Wang, M. L. Kuo, Y. T. Kuo, L. C. Liang, H. P. Cheng, Y. W. Yeh, Y. C. Tsai, M. T. Chan, W. S. Chiu, C. T. Chao, A. Chou, N. K. Yeh, Y. C. Ku, S. C. J Clin Anesth 2023

Adult, Humans, Retrospective Studies, Prospective Studies, *Delirium/diagnosis/epidemiology/etiology, Critical Illness, Intensive Care Units, Critically ill, Delirium, Intensive care unit, Machine learning, Prediction

Perioperative cerebral perfusion in aortic arch surgery: a potential link with neurological outcome Weijs, R. W. J. Tromp, S. C. Heijmen, R. H. Seeber, A. A. van Belle-van Haaren, Njcw Claassen, Jahr Thijssen, D. H. J. Eur J Cardiothorac Surg 2023

Humans, Aorta, Thoracic/diagnostic imaging/surgery, *Brain Ischemia/etiology/prevention & control, Retrospective Studies, *Stroke/etiology/prevention & control, Perfusion, *Ischemic Stroke, Cerebrovascular Circulation/physiology, *Delirium, Treatment Outcome, Postoperative Complications/prevention & control, *Aortic Aneurysm, Thoracic/surgery, Antegrade selective cerebral perfusion, Aortic surgery, Cerebral circulation, Perioperative management, Postoperative complication, Thoracic aorta

Preoperative Cognitive Impairment and Postoperative Delirium in Elderly Surgical Patients: A Retrospective Large Cohort Study (The CIPOD Study) Weiss, Y. Zac, L. Refaeli, E. Ben-Yishai, S. Zegerman, A. Cohen, B. Matot, I. Ann Surg 2023

Humans, Aged, *Emergence Delirium/complications, *Delirium/diagnosis/epidemiology/etiology, Retrospective Studies, Cohort Studies, Prospective Studies, *Cognitive Dysfunction/diagnosis/epidemiology, Postoperative Complications/etiology, Risk Factors

Contribution of Different Brain Disorders and Multimorbidity to Delirium Superimposed Dementia (DSD) Wetterling, T. Junghanns, K. Geriatrics (Basel) 2023

brain infarction, deliriumm dementia, multimorbidity, white matter hyperintensities

Prevalence and Risk Factors for Intensive Care Unit Delirium After Traumatic Brain Injury: A Retrospective Cohort Study Wilson, L. D. Maiga, A. W. Lombardo, S. Nordness, M. F. Haddad, D. N. Rakhit, S. Smith, L. F. Rivera, E. L. Cook, M. R. Thompson, J. L. Raman, R. Patel, M. B. Neurocrit Care 2023

Adult, Humans, Retrospective Studies, Prevalence, *Brain Injuries,, Traumatic/complications/epidemiology, Risk Factors, Intensive Care Units, *Subarachnoid Hemorrhage/complications, *Delirium/epidemiology/etiology, Glasgow Coma Scale,Critical illness, Delirium, Mental status, Predictors, Traumatic brain injury

Moderate-to-high risk of obstructive sleep apnea with excessive daytime sleepiness is associated with postoperative neurocognitive disorders: a prospective one-year follow-up cohort study Wu, W. Pu, L. Hu, X. Chen, Q. Wang, G. Wang, Y. Front Neurosci 2023

excessive daytime sleepiness, obstructive sleep apnea, older adults, perioperative neurocognitive disorders, surgery

Effect of Dexmedetomidine on Posttraumatic Stress Disorder in Patients Undergoing Emergency Trauma Surgery: A Randomized Clinical Trial Yu, Y. Li, Y. Han, D. Gong, C. Wang, L. Li, B. Yao, R. Zhu, Y. JAMA Netw Open 2023

Male, Humans, Adult, *Dexmedetomidine/therapeutic use/adverse effects, *Stress Disorders, Post-Traumatic/epidemiology/prevention & control, Saline Solution, *Emergence Delirium/chemically induced, Administration, Intravenous

Regional versus general anesthesia in older patients for hip fracture surgery: a systematic review and meta-analysis of randomized controlled trials Zhou, S. L. Zhang, S. Y. Si, H. B. Shen, B. J Orthop Surg Res 2023

Humans, Aged, Randomized Controlled Trials as Topic, *Hip Fractures/surgery, Anesthesia, General/adverse effects, *Plastic Surgery Procedures, *Delirium, Anesthesia, General, Hip fracture, Meta-analysis, Regional

Delirium in Medically Hospitalized Patients: Prevalence, Recognition and Risk Factors: A Prospective Cohort Study Al Farsi, R. S. Al Alawi, A. M. Al Huraizi, A. R. Al-Saadi, T. Al-Hamadani, N. Al Zeedy, K. Al-Maqbali, J. S. J Clin Med 2023

delirium, elderly, incidence, prevalence, risk factors

Delirium detection using wearable sensors and machine learning in patients with intracerebral hemorrhage Ahmed, A. Garcia-Agundez, A. Petrovic, I. Radaei, F. Fife, J. Zhou, J. Karas, H. Moody, S. Drake, J. Jones, R. N. Eickhoff, C. Reznik, M. E. Front Neurol 2023

actigraphy, delirium, intracerebral hemorrhage, machine learning, neurocritical care, stroke, wearable electronic devices

Associations of postoperative delirium with activities of daily living in older people after major surgery: A prospective cohort study Aldwikat, R. K. Manias, E. Holmes, A. C. Tomlinson, E. Nicholson, P. J Clin Nurs 2023

activities of daily living, cognition, older surgical patients, post-anaesthetic care unit, postoperative delirium

Association Between Risk of Stroke and Delirium After Cardiac Surgery and a New Electroencephalogram Index of Interhemispheric Similarity Baron Shahaf, D. Hight, D. Kaiser, H. Shahaf, G. J Cardiothorac Vasc Anesth 2023

Eeg, Lir, delirium, stroke

Melatonin and Ramelteon for the treatment of delirium: A systematic review and meta-analysis Beaucage-Charron, J. Rinfret, J. Coveney, R. Williamson, D. J Psychosom Res 2023

Humans, Aged, *Melatonin/therapeutic use, *Delirium/drug therapy, *Indenes/therapeutic use, *Antipsychotic Agents/therapeutic use, Delirium, Melatonergic agonist, Melatonin, Ramelteon, Treatment

A Core Outcome Set for Interventions to Prevent and/or Treat Delirium in Palliative Care Bryans, A. Siddiqi, N. Burry, L. Clarke, M. Koffman, J. Agar, M. R. Rose, L. J Pain Symptom Manage 2023

Delirium, clinical trials, core outcome set, palliative care

Delirium in the Era of COVID-19 Byrnes, T. Pate, K. Cochran, A. R. Belin, L. J Nurs Care Qual 2023

delirium, covid-19, older adults,

Leveraging the Electronic Health Record to Implement Emergency Department Delirium Screening Chary, A. N. Brickhouse, E. Torres, B. Santangelo, I. Carpenter, C. R. Liu, S. W. Godwin, K. M. Naik, A. D. Singh, H. Kennedy, M. Appl Clin Inform 2023

Humans, Aged, *Electronic Health Records, Emergency Service, Hospital, Attitude of Health Personnel, *Delirium/diagnosis

Cigarette smoking is linked to an increased risk of delirium following arthroplasty in patients suffering from osteoarthritic pain Chen, J. R. Chen, J. Q. Hu, J. C. Huang, R. S. Shen, L. Gu, H. Chai, X. Q. Wang, D. CNS Neurosci Ther 2023

osteoarthritis, postoperative delirium, smoking, total knee arthroplasty

Neurological Examination Frequency and Time-to-Delirium After Traumatic Brain Injury Chotai, S. Chen, J. W. Turer, R. Smith, C. Kelly, P. D. Bhamidipati, A. Davis, P. McCarthy, J. T. Bendfeldt, G. A. Peyton, M. B. Dennis, B. M. Terry, D. P. Guillamondegui, O. Yengo-Kahn, A. M. Neurosurgery Neurological Examination Frequency and Time-to-Delirium After Traumatic Brain Injury

neurological, traumatic brain injury, delirium, time-to-delirium, ICU, CAM-ICU

Effect of inhaled anaesthetics on cognitive and psychiatric outcomes in critically ill adults: a systematic review and meta-analysis Cuninghame, S. Jerath, A. Gorsky, K. Sivajohan, A. Francoeur, C. Withington, D. Burry, L. Cuthbertson, B. H. Orser, B. A. Martin, C. Owen, A. M. Slessarev, M. Br J Anaesth 2023

cognition, critical care medicine, delirium, post-ICU syndrome, psychiatric, sedation

The Delirium Interview as a new reference standard in studies on delirium assessment tools Ditzel, F. L. Slooter, A. J. C. van den Boogaard, M. Boonstra, M. van Nesselrooij, T. A. Kromkamp, M. Pop-Purceleanu, M. Rood, P. J. T. Osse, R. J. Chan, C. K. MacLullich, A. M. J. Tieges, Z. Neufeld, K. J. Hut, S. C. A. J Am Geriatr Soc 2023

Humans, Male, Aged, Aged, 80 and over, Female, Prospective Studies, *Intensive Care Units, *Delirium/diagnosis, Critical Care, Reference Standards, cognitive assessment, delirium, neuropsychological tests, reference standard

Development and validation of an international preoperative risk assessment model for postoperative delirium Dodsworth, B. T. Reeve, K. Falco, L. Hueting, T. Sadeghirad, B. Mbuagbaw, L. Goettel, N. Schmutz Gelsomino, N. Age Ageing 2023

Humans, Aged, *Emergence Delirium/complications, *Delirium/diagnosis/etiology/prevention & control, Risk Factors, Postoperative Complications/diagnosis/etiology/prevention & control, Risk Assessment, C-Reactive Protein, algorithm, clinical practice, older people, postoperative delirium, risk prediction

Emergency Department Length of Stay Is Associated with Delirium in Older Adults Elder, N. M. Mumma, B. E. Maeda, M. Y. Tancredi, D. J. Tyler, K. R. West J Emerg Med 2023

Humans, Female, Aged, Male, Length of Stay, Retrospective Studies, *Delirium/epidemiology, Prospective Studies, Risk Factors, Emergency Service, Hospital, *Dementia

'It's tough. It is hard': A qualitative interview study of staff and volunteers caring for hospice in-patients with delirium Featherstone, I. Siddiqi, N. Jones, L. Coppo, E. Sheldon, T. Hosie, A. Wolkowski, A. Bush, S. H. Taylor, J. Teodorczuk, A. Johnson, M. J. Palliat Med 2023

Humans, *Hospices, Palliative Care/psychology, *Hospice Care, Qualitative Research, Volunteers, *Delirium/therapy, Delirium, hospices, palliative care, psychological distress, qualitative research

Metabolic syndrome and the risk of postoperative delirium and postoperative cognitive dysfunction: a multi-centre cohort study Feinkohl, I. Janke, J. Slooter, A. J. C. Winterer, G. Spies, C. Pischon, T. Br J Anaesth 2023

cholesterol, epidemiology, metabolic syndrome, obesity, postoperative cognitive dysfunction, postoperative delirium

Delirium After Traumatic Brain Injury: Prediction by Location and Size of Brain Lesion Han, S. J. Suh, J. H. Lee, J. Y. Kim, S. J. Ann Rehabil Med 2023

Delirium, Intracranial hemorrhages, Traumatic brain injury

Meta-analysis of the effect of entropy-assisted general anesthesia on the quality of postoperative recovery He, B. Zhang, N. Peng, M. Medicine (Baltimore) 2023

Humans, Postoperative Nausea and Vomiting/epidemiology/prevention & control, *Emergence Delirium, Entropy, *Intraoperative Awareness, Anesthesia, General/adverse effects, Randomized Controlled Trials as Topic

Sex-specific clinical characteristics and treatment responses in delirium management: findings from a prospective cohort study in elderly patients Hildenbrand, F. F. Boettger, S. Spiller, T. Schubert, M. Ernst, J. von Känel, R. Zipser, C. M. Int Clin Psychopharmacol 2023

delirium, incidence, sex differences, observational, elderly

A predictive scoring system for postoperative delirium in the elderly patients with intertrochanteric fracture Hu, Y. Yang, M. BMC Surg 2023

Humans, Aged, Infant, Retrospective Studies, *Emergence Delirium/etiology, *Fracture Fixation, Intramedullary/adverse effects, Treatment Outcome, *Hip, Fractures/complications/surgery, *Stroke/etiology, Elderly, Intertrochanteric fracture, Postoperative delirium, Prediction, Reduction and internal fixation, Scoring system

A single preoperative low-dose dexamethasone may reduce the incidence and severity of postoperative delirium in the geriatric intertrochanteric fracture patients with internal fixation surgery: an exploratory analysis of a randomized, placebo-controlled t Huang, J. W. Yang, Y. F. Gao, X. S. Xu, Z. H. J Orthop Surg Res 2023

Humans, Aged, *Emergence Delirium/drug therapy, Postoperative, Complications/epidemiology/etiology/prevention & control, Prospective Studies
Incidence, *Delirium/epidemiology/etiology/prevention & control, *Hip Fractures/surgery/drug therapy, Dexamethasone, Intertrochanteric fractures, Postoperative delirium, The elderly

Incidence of postoperative delirium in older adults undergoing surgical procedures: A systematic literature review and meta-analysis Igwe, E. O. Nealon, J. O'Shaughnessy, P. Bowden, A. Chang, H. R. Ho, M. H. Montayre, J. Montgomery, A. Rolls, K. Chou, K. R. Chen, K. H. Traynor, V. Smerdely, P. Worldviews Evid Based Nurs 2023

Humans, Aged, *Emergence Delirium/complications, *Delirium/epidemiology/etiology/diagnosis, Postoperative, Complications/epidemiology/etiology, Incidence, Risk Factors, meta-analysis
older people, postoperative delirium, systematic review

Music to prevent deliriUm during neuroSurgerY (MUSYC): a single-centre, prospective randomised controlled trial Kappen, P. R. Mos, M. I. Jeekel, J. Dirven, C. M. F. Kushner, S. A. Osse, R. J. Coesmans, M. Poley, M. J. van Schie, M. S. van der Holt, B. Klimek, M. Vincent, Ajpe BMJ Open 2023

Adult, Humans, *Music, *Neurosurgery, Prospective Studies, *Delirium/etiology/prevention & control/diagnosis, Neurosurgical, Procedures/adverse effects, clinical trials, complementary medicine, delirium & cognitive disorders, neurosurgery, preventive medicine