Delirium Bibliography

Delirium Bibliography books graphicWhat is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!

How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.

Reference Information

Title
A single preoperative low-dose dexamethasone may reduce the incidence and severity of postoperative delirium in the geriatric intertrochanteric fracture patients with internal fixation surgery: an exploratory analysis of a randomized, placebo-controlled t
Authors
Huang, J. W. Yang, Y. F. Gao, X. S. Xu, Z. H.
Year
2023
Journal
J Orthop Surg Res
Abstract

OBJECTIVE: Postoperative delirium (POD) is a common complication along with poor prognosis in geriatric intertrochanteric fracture (ITF) patients. However, the prevention and treatment of POD remain unclear. Previous studies have confirmed that POD is essentially a consequence of neuro-inflammatory responses. Dexamethasone is a glucocorticoid with comprehensive anti-inflammatory effects, while a high dose of dexamethasone correlates with many side effects or even adverse consequences. Thus, this prospective study aims to discuss whether a single preoperative low-dose dexamethasone can reduce the impact of POD on geriatric ITF patients with internal fixation surgery. METHODS: Between June 2020 and October 2022, there were 219 consecutive ITF patients assessed in our department. Of the 219 ITF patients, 160 cases who met the inclusion and exclusion criteria were finally enrolled and randomly allocated to the dexamethasone group and the placebo group (80 geriatric ITF patients in each group) in this prospective study. The patients in the dexamethasone group received intravenous 10 mg (2 ml) dexamethasone while the patients in the placebo group received intravenous 2 ml saline in 30 min before being sent to the operating room, respectively. The baseline characteristics, surgical information, incidence and severity of POD as the efficacy-related outcomes, and infection events and hyperglycemia as safety-related outcomes (adverse events), were collected and analyzed between the two groups. The severity of POD was evaluated by Memorial Delirium Assessment Scale (MDAS) score. RESULTS: There were no differences in baseline characteristics and surgical information between the dexamethasone group and the placebo group. The dexamethasone group had a lower incidence of POD than the placebo group within the first 5 days after surgery [(9/80, 11.3% vs. 21/80, 26.3%, RR = 0.83, 95% CI 0.71-0.97, P = 0.015]. The dexamethasone group had lower MDAS scores (Mean ± SD) than the placebo group [13.2 ± 1.0 (range 11 to 15) vs. 15.48 ± 2.9 (range 9 to 20), P = 0.011, effect size = 0.514]. There were no differences in infection events and hyperglycemia between the two groups. CONCLUSIONS: A single preoperative low-dose dexamethasone may reduce the incidence and severity of POD in geriatric ITF patients with internal fixation surgery. TRIAL REGISTRATION: ChiCTR2200055281.

PMID

PMID: 37337260

PMCID:PMC10280884

 

Keywords

Humans, Aged, *Emergence Delirium/drug therapy, Postoperative, Complications/epidemiology/etiology/prevention & control, Prospective Studies
Incidence, *Delirium/epidemiology/etiology/prevention & control, *Hip Fractures/surgery/drug therapy, Dexamethasone, Intertrochanteric fractures, Postoperative delirium, The elderly

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Total Records Found: 5776, showing 100 per page
TitleAuthorsJournalYearKeywords
Comparison of the effectiveness of delirium evaluation tools in intensive care patients: pre-deliric versions 1 and 2, E-pre-deliric and ICDSC Kucuk, O. Memis, D. Inal, M. T. Turan, F. N. Memis, I. Eur Rev Med Pharmacol Sci 2023

Male
Humans
Adult
Middle Aged
Aged
Female
*Delirium/diagnosis
Checklist
Reproducibility of Results
Prospective Studies
Critical Care/methods
Intensive Care Units

New-onset delirium during hospitalization in older adults: incidence and risk factors Lami Pereira, R. Bojanini Molina, L. Wilger, K. Hedges, M. S. Tolaymat, L. Haga, C. Walker, A. Gillis, M. Yin, M. Dawson, N. L. Hosp Pract (1995) 2023

Humans
Aged
Incidence
Retrospective Studies
*Delirium/epidemiology/diagnosis
Hospitalization
Length of Stay
Risk Factors
Confusion
Delirium
Encephalopathy
elderly

The Potential Value of Systemic Inflammation Response Index on Delirium After Hip Arthroplasty Surgery in Older Patients: A Retrospective Study Lu, W. Lin, S. Wang, C. Jin, P. Bian, J. Int J Gen Med 2023

geriatric
hip arthroplasty
neutrophil to lymphocyte ratio
platelet to lymphocyte ratio
postoperative delirium
systemic inflammation response index

Incidence of delirium in older people with cancer: Systematic review and meta-analysis Martínez-Arnau, F. M. Buigues, C. Pérez-Ros, P. Eur J Oncol Nurs 2023

Cancer
Delirium
Incidence
Older
meta-Analyses

Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) for the diagnosis of delirium in adults in critical care settings Miranda, F. Gonzalez, F. Plana, M. N. Zamora, J. Quinn, T. J. Seron, P. Cochrane Database Syst Rev 2023

Adult
Humans
Middle Aged
Aged
*Intensive Care Units
Sensitivity and Specificity
*Delirium/diagnosis
Critical Care

Exploration of key drug target proteins highlighting their related regulatory molecules, functional pathways and drug candidates associated with delirium: evidence from meta-data analyses Mosharaf, M. P. Alam, K. Gow, J. Mahumud, R. A. BMC Geriatr 2023

Humans
Gene Regulatory Networks
Proteomics
*MicroRNAs/genetics
Transcription Factors/genetics
*Delirium/drug therapy
Delirium
Drug repurposing
Hub-proteins
Transcription factors
microRNA

Development of postoperative delirium prediction models in patients undergoing cardiovascular surgery using machine learning algorithms Nagata, C. Hata, M. Miyazaki, Y. Masuda, H. Wada, T. Kimura, T. Fujii, M. Sakurai, Y. Matsubara, Y. Yoshida, K. Miyagawa, S. Ikeda, M. Ueno, T. Sci Rep 2023

delirium, postoperative, machine learning, cardiovascular, hospital

EEG microstate quantifiers and state space descriptors during anaesthesia in patients with postoperative delirium: a descriptive analysis Neuner, B. Wolter, S. McCarthy, W. J. Spies, C. Cunningham, C. Radtke, F. M. Franck, M. Koenig, T. Brain Commun 2023

EEG microstates
EEG state space descriptors
anaesthesia
multichannel EEG
postoperative delirium

Efficacy and Safety of Risperidone in Patients With Delirium: The RIDDLE Pilot Study Nguyen, P. V. Vu, T. T. M. Aust Crit CareJ Clin Psychopharmacol 2023

delirium, pilot study, risperidone, delirium rating scale, hospital

Intensive care unit nurses' perception of three different methods for delirium screening: A survey (DELIS-3) Nielsen, A. H. Larsen, L. K. Collet, M. O. Lehmkuhl, L. Bekker, C. Jensen, J. F. Laerkner, E. Nielsen, T. A. Rossen, B. S. Thorn, L. Laursen, E. Fischer, S. Villumsen, M. Shiv, L. H. Høgh, M. Rahr, M. N. Svenningsen, H. Aust Crit Care 2023

Humans
*Delirium/diagnosis
Cross-Sectional Studies
Intensive Care Units
Critical Care/methods
Perception
*Nurses
Critical care
Critical illness
Delirium
Encephalopathy
Intensive care nursing
Screening

Melatonin and Melatonin Agonists for Prevention of Delirium in the Cardiac Surgical ICU: A Meta-analysis Niyogi, S. G. Naskar, C. Singh, A. Kumar, B. Grover, S. Indian J Crit Care Med 2023

Cardiac critical care
Melatonin
Postoperative delirium

Association between Neuron-Specific Enolase, Memory Function, and Postoperative Delirium after Transfemoral Aortic Valve Replacement Nübel, J. Buhre, C. Hoffmeister, M. Oess, S. Labrenz, O. Jost, K. Hauptmann, M. Schön, J. Fritz, G. Butter, C. Haase-Fielitz, A. J Cardiovasc Dev Dis 2023

Tavr
cognitive assessment
memory function
neuron-specific enolase
postoperative delirium

A retrospective, cross-sectional analysis of delirium in burn injury compared to other surgical specialities O'Brien, A. Hopkins, J. Boardman, G. Stanley, G. Daly, P. Martin, L. Wood, F. Burns 2023

Humans
Intensive Care Units
Retrospective Studies
Cross-Sectional Studies
*Delirium/epidemiology/etiology
*Burns/complications/epidemiology/surgery
Burns
Delirium
General surgery
Intensive care
Orthopaedic surgery
Plastic surgery

Postoperative Use of the Muscle Relaxants Baclofen and/or Cyclobenzaprine Associated With an Increased Risk of Delirium Following Lumbar Fusion Perez, E. A. Ray, E. Gold, C. J. Park, B. J. Piscopo, A. Carnahan, R. M. Banks, M. Sanders, R. D. Olinger, C. R. Mueller, R. N. Woodroffe, R. W. Spine (Phila Pa 1976) 2023

Humans
Aged
Cohort Studies
*Baclofen/adverse effects
Retrospective Studies
*Emergence Delirium/complications
Muscles
Postoperative Complications/chemically induced/epidemiology

Extracellular Vesicles as Possible Plasma Markers and Mediators in Patients with Sepsis-Associated Delirium-A Pilot Study Plaschke, K. Brenner, T. Fiedler, M. O. Hölle, T. von der Forst, M. Wolf, R. C. Kopitz, J. Gebert, J. Weigand, M. A. Int J Mol Sci 2023

Humans
Pilot Projects
*Sepsis-Associated Encephalopathy/metabolism
Longitudinal Studies
*Extracellular Vesicles/metabolism
Proteome/metabolism
Biomarkers/metabolism
Aryldialkylphosphatase/metabolism
intensive care unit
plasma extracellular vesicles (EVs)
proteomics
sepsis-associated delirium (SAD)

Rest-activity patterns associated with delirium in patients with intracerebral hemorrhage Reznik, M. E. Mintz, N. Moody, S. Drake, J. Margolis, S. A. Rudolph, J. L. LaBuzetta, J. N. Kamdar, B. B. Jones, R. N. J Neurol Sci 2023

Humans
*Delirium/etiology
Cerebral Hemorrhage/complications
*Stroke/complications
Actigraphy
Hospitalization
Delirium
Sleep
Stroke

Development and validation of delirium prediction models for noncardiac surgery patients Rössler, J. Shah, K. Medellin, S. Turan, A. Ruetzler, K. Singh, M. Sessler, D. I. Maheshwari, K. J Pain Palliat Care Pharmacother 2023

Anesthesia
Delirium
Dynamic modeling
Machine learning
Noncardiac surgery
Postoperative
Prediction

Effects of Opioids, Steroids, Benzodiazepines, Anticholinergics, and Antihistamines on the Efficacy of Antipsychotics for Treating Delirium in End-of-Life Adult Patients Undergoing Palliative Care Sato, J. Tanaka, R. J Pain Palliat Care Pharmacother 2023

Humans
Adult
*Antipsychotic Agents/therapeutic use
Benzodiazepines
Palliative Care/methods
Cholinergic Antagonists/therapeutic use
Analgesics, Opioid/therapeutic use
Retrospective Studies
*Delirium/drug therapy
Death
Histamine Antagonists/therapeutic use
Steroids/therapeutic use
Delirium
antipsychotics
opioids
steroids

Clinical Prediction Models for Hospital-Induced Delirium Using Structured and Unstructured Electronic Health Record Data: Protocol for a Development and Validation Study Ser, S. E. Shear, K. Snigurska, U. A. Prosperi, M. Wu, Y. Magoc, T. Bjarnadottir, R. I. Lucero, R. J. JMIR Res Protoc 2023

big data
clinical text
data science
delirium
free text
hospital acquired
hospital induced
hospital-acquired condition
machine learning
model
models
natural language processing
predict
prediction
predictive
risk
risk factors
structured
text data
unstructured

A Prospective Randomized Study of the Herbal Medicine Yokukansan for Preventing Delirium After Gastrointestinal Cancer Surgery Tanio, A. Yamamoto, M. Uejima, C. Tada, Y. Yamanashi, T. Matsuo, R. Miura, A. Kajitani, N. Nishiguchi, T. Iwata, M. Fujiwara, Y. Yonago Acta Med 2023

gastrointestinal cancer
postoperative delirium
yokukansan

A protocol of an international validation study to assess the clinical accuracy of the eDIS-ICU delirium screening tool Tronstad, O. Patterson, S. Sutt, A. L. Pearse, I. Hay, K. Liu, K. Sato, K. Koga, Y. Matsuoka, A. Hongo, T. Rätsep, I. Fraser, J. F. Flaws, D. Aust Crit Care 2023

Humans
*Delirium/diagnosis
Australia
Intensive Care Units
Outcome Assessment, Health Care
New Zealand
Delirium
Delirium assessment
Electronic screening tool
Icu
Research protocol

Anaesthesia-related cognitive dysfunction following cardiothoracic surgery in late middle-age and younger adults: A scoping review Varpaei, H. A. Robbins, L. B. Ling, J. Lehto, R. H. Bender, C. M. Nurs Crit Care 2023

anaesthesia
cardiac
cognitive decline
critical care
delirium

Long-term mortality of critically ill patients with cancer and delirium who survived to discharge: a retrospective cohort study Vizzacchi, B. A. Pezzini, T. R. de Souza, J. M. Caruso, P. Nassar, A. P., Jr. Can J Anaesth 2023

Adult
Humans
Patient Discharge
*Delirium/epidemiology
Retrospective Studies
Critical Illness
Intensive Care Units
Psychomotor Agitation
*Neoplasms/complications
critical care
delirium
long-term care
mortality

The effect of anesthetic depth on postoperative delirium in older adults: a systematic review and meta-analysis Wang, Y. Zhu, H. Xu, F. Ding, Y. Zhao, S. Chen, X. BMC Geriatr 2023

Humans
Middle Aged
Aged
*Emergence Delirium
*Delirium/epidemiology
*Anesthetics
Anesthesia, General/adverse effects
Cognition
Postoperative Complications/etiology
Anesthetic depth
Bis
General anesthesia
Older adults
Postoperative delirium

Unveiling the nexus of postoperative fever and delirium in cardiac surgery: identifying predictors for enhanced patient care Wang, Y. P. Shen, B. B. Zhu, C. C. Li, L. Lu, S. Wang, D. J. Jin, H. Liu, Q. Wang, Z. Y. Ge, M. Front Cardiovasc Med 2023

Cpb
cardiac surgery
fever
postoperative delirium
prediction model

Long-term cognitive impairment after probable delirium in long-term care residents: A population-based retrospective cohort study Webber, C. Milani, C. Pugliese, M. Lawlor, P. G. Bush, S. H. Watt, C. Casey, G. Knoefel, F. Thavorn, K. Momoli, F. Tanuseputro, P. J Am Geriatr Soc 2023

cognitive decline
delirium
long-term care

Delirium Due to Potentially Avoidable Hospitalizations Among Older Adults Whittington, C. Skains, R. M. Zhang, Y. Osborne, J. D. O'Leary, T. Freeman, H. B. Martin, R. C. Vickers, J. K. Flood, K. L. Markland, A. D. Buford, T. W. Brown, C. J. Kennedy, R. E. J Gerontol A Biol Sci Med Sci 2023

ambulatory care sensitive conditions
delirium
older adults
potentially avoidable hospitalizations

Quantitative electroencephalography predicts postoperative delirium in cardiac surgical patients after cardiopulmonary bypass: a prospective observational study Xue, Y. Liu, W. Su, L. He, H. Chen, H. Long, Y. Front Med (Lausanne) 2023

cardiopulmonary bypass
critical care
delirium biomarkers
postoperative delirium
quantitative electroencephalography

Natural language processing to assess the epidemiology of delirium-suggestive behavioural disturbances in critically ill patients Young, M. Holmes, N. Robbins, R. Marhoon, N. Amjad, S. Neto, A. S. Bellomo, R. Crit Care Resusc 2021

Background: There is no gold standard approach for delirium diagnosis, making the assessment of its epidemiology difficult. Delirium can only be inferred though observation of behavioural disturbance and described with relevant nouns or adjectives. Objective: We aimed to use natural language processing (NLP) and its identification of words descriptive of behavioural disturbance to study the epidemiology of delirium in critically ill patients. Study design: Retrospective study using data collected from the electronic health records of a university-affiliated intensive care unit (ICU) in Melbourne, Australia. Participants: 12 375 patients Intervention: Analysis of electronic progress notes. Identification using NLP of at least one of a list of words describing behavioural disturbance within such notes. Results: We analysed 199 648 progress notes in 12 375 patients. Of these, 5108 patients (41.3%) had NLP-diagnosed behavioural disturbance (NLP-Dx-BD). Compared with those who did not have NLP-Dx-DB, these patients were older, more severely ill, and likely to have medical or unplanned admissions, neurological diagnosis, chronic kidney or liver disease and to receive mechanical ventilation and renal replacement therapy (P < 0.001). The unadjusted hospital mortality for NLP-Dx-BD patients was 14.1% versus 9.6% for patients without NLP-Dx-BD. After adjustment for baseline characteristics and illness severity, NLP-Dx-BD was not associated with increased risk of death (odds ratio [OR], 0.94; 95% CI, 0.80-1.10); a finding robust to multiple sensitivity, subgroups and time of observation subcohort analyses. In mechanically ventilated patients, NLP-Dx-BD was associated with decreased hospital mortality (OR, 0.80; 95% CI, 0.65-0.99) after adjustment for baseline severity of illness and year of admission. Conclusions: NLP enabled rapid assessment of large amounts of data identifying a population of ICU patients with typical high risk characteristics for delirium. Moreover, this technique enabled identification of previously poorly understood associations. Further investigations of this technique appear justified.

Association between intraoperative mean arterial pressure variability and postoperative delirium after hip fracture surgery: a retrospective cohort study Zhang, C. Song, Y. Wu, X. Miao, R. Lou, J. Ma, Y. Li, M. Mi, W. Cao, J. BMC Geriatr 2023

Aged
Humans
Aged, 80 and over
*Emergence Delirium
Arterial Pressure
Retrospective Studies
*Hip Fractures/surgery
Multivariate Analysis
Postoperative Complications/diagnosis/epidemiology/etiology
Risk Factors
Hip fracture
Mean arterial pressure variability
Postoperative delirium

Impact of Clinical Decision Support System Assisted prevention and management for Delirium on guideline adherence and cognitive load among Intensive Care Unit nurses (CDSSD-ICU): Protocol of a multicentre, cluster randomized trial Zhang, S. Ding, S. Cui, W. Li, X. Wei, J. Wu, Y. Int J Nurs Stud 2023

Humans
Guideline Adherence
Prospective Studies
Decision Support Systems, Clinical
Delirium/prevention & control/diagnosis
Intensive Care Units
Cognition
Randomized Controlled Trials

deliriumnetwork.org/bibliography/?pdb=8736 Int J Nurs Stud

Humans
Aged
*Delirium/prevention & control
Systematic Reviews as Topic
Risk Factors
Length of Stay
Accidental Falls
Acute confusion
Delirium
Non-pharmacological intervention
Older people

Non-pharmacological interventions to prevent and treat delirium in older people: An overview of systematic reviews Zhao, Q. Liu, S. Zhao, H. Dong, L. Zhu, X. Liu, J. Int J Nurs Stud 2023

Humans
Aged
*Delirium/prevention & control
Systematic Reviews as Topic
Risk Factors
Length of Stay
Accidental Falls
Acute confusion
Delirium
Non-pharmacological intervention
Older people

Online interpretable dynamic prediction models for postoperative delirium after cardiac surgery under cardiopulmonary bypass developed based on machine learning algorithms: A retrospective cohort study Zhao, X. Li, J. Xie, X. Fang, Z. Feng, Y. Zhong, Y. Chen, C. Huang, K. Ge, C. Shi, H. Si, Y. Zou, J. J Psychosom Res 2023

Cardiac surgery
Cardiopulmonary bypass
Dynamic prediction
Machine learning
Postoperative delirium
Pre- and post-operative models

Dementia and Postoperative Delirium in Surgical Hip Fracture Patients: Unveiling Contrasting Risk Factors and Implications Zhao, Y. Alderden, J. Missbrenner, N. J Gerontol Nurs 2023

Humans
Aged
*Emergence Delirium
*Hip Fractures/complications/surgery
*Geriatric Nursing
Risk Factors
*Dementia/complications

Diagnostic accuracy of the Family Confusion Assessment Method for delirium detection: A systematic review and meta-analysis Zhou, C. Wang, H. Wang, L. Zhou, Y. Wu, Q. J Am Geriatr Soc 2023

Fam-cam
caregiver
delirium
family
meta-analysis

The effects of a multidisciplinary pathway for perioperative management of patients with hip fracture Ackermann, L. L. Schwenk, E. S. Li, C. J. Vaile, J. R. Weitz, H. Hosp Pract (1995) 2023

Humans, Aged, Analgesics, Opioid/therapeutic use, Prospective Studies
*Hip Fractures/surgery, Pain, Postoperative/drug therapy/chemically induced/complications, Delirium, Hip fracture pathway
delirium, multidisciplinary care, pain management, perioperative hip fracture

Precision-based approaches to delirium in critical illness: A narrative review Ankravs, M. J. McKenzie, C. A. Kenes, M. T. Pharmacotherapy 2023

Humans, Delirium/diagnosis/drug therapy/etiology, Intensive Care Units
Critical Illness, Cognitive Dysfunction, Critical Care, biomarkers, delirium, phenotypes, precision medicine

Associations between early in-hospital medications and the development of delirium in patients with stroke Ryan, S. L. Liu, X. McKenna, V. Ghanta, M. Muniz, C. Renwick, R. Westover, M. B. Kimchi, E. Y. J Stroke Cerebrovasc Dis 2023

Humans
*Antipsychotic Agents/adverse effects
Retrospective Studies
*Delirium/chemically induced/diagnosis
Risk Factors
*Stroke/diagnosis/drug therapy/complications
Hypnotics and Sedatives/therapeutic use
Hospitals
Delirium
Medications
Polypharmacy
Stroke

Family-centered delirium prevention and treatment using video calls: the FACE Delirium trial Trabert, J. Schenk, A. Golbach, R. Püllen, R. Schütze, S. Eur Geriatr Med 2023

Delirium
Family
Pandemic
Prevention
Video calls

Early Onset Delirium During Hospitalization Increases In-Hospital and Postdischarge Mortality in COVID-19 Patients: A Multicenter Prospective Study Trevisan, C. Grande, G. Rebora, P. Zucchelli, A. Valsecchi, M. G. Focà, E. Ecarnot, F. Marengoni, A. Bellelli, G. J Clin Psychiatry 2023

Humans
Aged
Prospective Studies
Aftercare
*covid-19
Patient Discharge
Hospitalization
Hospitals
*Delirium

Accuracy of a clinical decision support system based on the 3-minute diagnostic interview for CAM-defined delirium: A validation study(✰) Wang, J. Ji, M. Huang, Y. Yang, F. Wu, Y. Geriatr Nurs 2023

Humans
Aged
*Delirium/diagnosis
*Decision Support Systems, Clinical
Sensitivity and Specificity
*Cognitive Dysfunction
Reproducibility of Results
Clinical decision support system
Delirium
Older adult
Validation
declare.

Psychological stress and associated factors in caring for patients with delirium among intensive care unit nurses: A cross-sectional study Wang, Y. Li, L. Tan, S. Guan, Y. Luo, X. Aust Crit Care 2023

Humans
Cross-Sectional Studies
Stress, Psychological/psychology
Intensive Care Units
*Nurse Administrators
*Delirium
Patient Care
Surveys and Questionnaires
*Nurses
Delirium
ICU nurses
Nursing
Psychological stress

Inflammatory biomarkers and delirium: a Mendelian randomization study Yu, M. Li, Y. Li, B. Ge, Q. Front Aging Neurosci 2023

Il-6
Mendelian randomization
delirium
inflammatory markers
summary genome-wide association study

 

Knowledge, attitude and practice regarding hypoactive delirium among ICU nurses: A nationwide cross-sectional study Yu, M. Mi, J. Zhang, C. Chen, H. Luo, X. Nurse Educ Pract 2023

Attitude
Delirium subtype
Hypoactive delirium
ICU nurse
Knowledge
Practice
competing financial interests or personal relationships that could have appeared
to influence the work reported in this paper.

Potentials of Acetylcholinesterase and Butyrylcholinesterase Alterations in On-Pump Coronary Artery Bypass Surgery in Postoperative Delirium: An Observational Trial Zajonz, T. S. Kunzemann, C. Schreiner, A. L. Beckert, F. Schneck, E. Boening, A. Markmann, M. Sander, M. Koch, C. J Clin Med 2023

cardiac surgery
cardiopulmonary bypass
intensive care
postoperative care
postoperative delirium
preoperative patient evaluation and improvement

Peripheral cholinesterase activity is not correlated with postoperative delirium in urological surgery Zangl, Q. Sprinz, B. von Dossow, V. J Perioper Pract 2023

Acetylcholinesterase
Butyrylcholinesterase
Pocd
Pod
Postoperative cognitive deficite
Postoperatvie delirium
Surgery

Biologic correlates associated with poor functional recovery after delirium: A nested prospective cohort study Dasgupta, M. Brymer, C. Health Sci Rep 2023

activities of daily living
aged
delirium
prognosis

ICU Delirium Is Associated with Cardiovascular Burden and Higher Mortality in Patients with Severe COVID-19 Pneumonia Gutowski, M. Klimkiewicz, J. Michałowski, A. Ordak, M. Możański, M. Lubas, A. J Clin Med 2023

Covid-19
Icu
delirium

Analysis of risk factors for postoperative delirium in middle-aged and elderly fracture patients in the perioperative period An, Z. Xiao, L. Chen, C. Wu, L. Wei, H. Zhang, X. Dong, L. Sci Rep 2023

Aged
Humans
Middle Aged
*Emergence Delirium/epidemiology/etiology
Blood Loss, Surgical
*Delirium/etiology/complications
Postoperative Complications/epidemiology/etiology
*Hip Fractures/surgery/complications
Perioperative Period/adverse effects
Anesthesia, General/adverse effects
Risk Factors

Korkatti-Puoskari, N. Tiihonen, M. Caballero-Mora, M. A. Topinkova, E. Szczerbińska, K. Hartikainen, S. Therapeutic dilemma's: antipsychotics use for neuropsychiatric symptoms of dementia, delirium and insomnia and risk of falling in older adults, a clinical review Eur Geriatr Med 2023

Humans
Aged
*Antipsychotic Agents/adverse effects
Accidental Falls/prevention & control
*Sleep Initiation and Maintenance Disorders/chemically induced/drug therapy
*Dementia/drug therapy/chemically induced
*Delirium/chemically induced/drug therapy
Antipsychotics
Delirium
Dementia
Falls
Insomnia
Older adults

The efficacy and safety of haloperidol for the treatment of delirium in critically ill patients: a systematic review and meta-analysis of randomized controlled trials Huang, J. Zheng, H. Zhu, X. Zhang, K. Ping, X. Front Med (Lausanne) 2023

Icu
critically ill adult patients
delirium
haloperidol
meta-analysis
commercial or financial relationships that could be construed as a potential
conflict of interest.

A prospective randomized study examining the impact of intravenous versus inhalational anesthesia on postoperative cognitive decline and delirium Farrer, T. J. Monk, T. G. McDonagh, D. L. Martin, G. Pieper, C. F. Koltai, D. Appl Neuropsychol Adult 2023

Anesthesia type
Pocd
cognition
older adults

Factors Associated with Improvement in Activities of Daily Living during Hospitalization: A Retrospective Study of Older Patients with Hip Fractures Takeda, K. Wada, M. Yorozuya, K. Hara, Y. Watanabe, T. Hanaoka, H. Ann Geriatr Med Res 2023

Activities of daily living
Apathy
Behavioral symptoms
Delirium
Dementia
Hip fractures

Associations Between Dysphagia and Adverse Health Outcomes in Older Adults with Dementia in Intensive Care Units: A Retrospective Cohort Study Cheng, H. Deng, X. Li, J. Tang, Y. Yuan, S. Huang, X. Wang, Z. Zhou, F. Lyu, J. Clin Interv Aging 2023

Humans
Female
Aged
Aged, 80 and over
Male
Retrospective Studies
*Pressure Ulcer
Intensive Care Units
*Deglutition Disorders/epidemiology/diagnosis
*Pneumonia, Aspiration/etiology/complications
*Delirium/epidemiology
*Dementia/complications/epidemiology
Outcome Assessment, Health Care
delirium
dementia
dysphagia
intensive care unit
mortality
older adults

Microvascular reconstruction for oral cancer in older adult patients: the impact of age on surgical outcomes Kouketsu, A. Kaneuji, T. Yamaguma, Y. Yamauchi, K. Sugiura, T. Takahashi, T. Ito, H. Yamashita, Y. Oral Surg Oral Med Oral Pathol Oral Radiol 2023

oral, cancer, surgical, adults, elderly

Postoperative delirium is a risk factor of institutionalization after hip fracture: an observational cohort study Labaste, F. Delort, F. Ferré, F. Bounes, F. Reina, N. Valet, P. Dray, C. Minville, V. Front Med (Lausanne) 2023

delirium
dependence
hip fracture
institutionalization
orthopedic surgery
commercial or financial relationships that could be construed as a potential
conflict of interest.

Prognostic significance of delirium in patients with heart failure: a systematic review and meta-analysis Niu, Z. Zhou, J. Li, Y. Front Cardiovasc Med 2023

delirium
heart failure
hospitalization
meta-analysis
mortality

Postoperative delirium in 47 379 individuals undergoing transcatheter aortic valve replacement: a systematic review and meta-analysis Ochani, S. Adnan, A. Siddiqui, A. Kalwar, A. Kukreja, S. Ahmad, M. Ashraf, M. H. Asghar, M. A. Ann Med Surg (Lond) 2023

Cam, Tavr, confusion assessment method, delirium, stroke, transcatheter aortic valve replacement

ICU Readmission in Injured Older Adults: Modifiable Risk Factors and Implications Agoubi, L. L. Reimel, B. A. Maine, R. G. O'Connell, K. M. Maier, R. V. McIntyre, L. K. J Trauma Acute Care Surg 2023

ICU, delirium, older adults, risk factors, readmission

Motorist disorientation syndrome; clinical features and vestibular findings Ainsworth, C. Davies, R. Colvin, I. Murdin, L. J Vestib Res 2023

Humans
Female
Adult
Dizziness/diagnosis/etiology
Vertigo/diagnosis
*Vestibular Diseases/diagnosis
Confusion/diagnosis
*Migraine Disorders
Motorist Disorientation Syndrome (MDS)

External validity of an automated delirium prediction model (DEMO) and comparison to the manual VMS-questions: a retrospective cohort study Ali, M. I. M. Kalkman, G. A. Wijers, C. H. W. Fleuren, Hwha Kramers, C. de Wit, Hajm Int J Clin Pharm 2023

Humans
Retrospective Studies
*Hospitalization
Hospitals
*Delirium/diagnosis/epidemiology/prevention & control
Automated model
Delirium
External validation
Hospitalized patients
Prevention measures
Risk prediction

Role of Intraoperative Neuromonitoring to Predict Postoperative Delirium in Cardiovascular Surgery Al-Qudah, A. M. Ta'ani, O. A. Thirumala, P. D. Sultan, I. Visweswaran, S. Nadkarni, N. Kiselevskaya, V. Crammond, D. J. Balzer, J. Anetakis, K. M. Shandal, V. Subramanium, K. Subramanium, B. Sadhasivam, S. J Cardiothorac Vasc Anesth 2023

Eeg, Ionm, Ssep, cardiac, delirium, postoperative

Comparison of the hemodynamic effects of opioid-based versus lidocaine-based induction of anesthesia with propofol in older adults: a randomized controlled trial Amin, S. M. Hasanin, A. ElSayed, O. S. Mostafa, M. Khaled, D. Arafa, A. S. Hassan, A. Anaesth Crit Care Pain Med 2023

Humans
Aged
*Propofol/adverse effects
Lidocaine
Analgesics, Opioid/therapeutic use
Anesthetics, Intravenous
*Emergence Delirium
Fentanyl
Hemodynamics
Anesthesia, General
*Hypotension/chemically induced/epidemiology
Norepinephrine/therapeutic use
General anesthesia
Hypotension
Older adult
Propofol

Effect of pharmacist-led intervention protocol on preventing postoperative delirium after elective cardiovascular surgery Asai, Y. Yanagawa, T. Takahashi, M. PLoS One 2023

Adult, Humans, *Emergence Delirium, Pharmacists, Retrospective Studies, Benzodiazepines/adverse effects

Taming Postoperative Delirium with Dexmedetomidine: A Review of the Therapeutic Agent's Neuroprotective Effects following Surgery Bargnes, V., 3rd Oliver, B. Wang, E. Greenspan, S. Jin, Z. Yeung, I. Bergese, S. Pharmaceuticals (Basel) 2023

dexmedetomidine
neuroprotection
perioperative neurocognitive disorder
postoperative delirium

Level of implementation of pain management and early mobilization strategies to prevent delirium in geriatric trauma patients: A mixed-methods study Beaudoin, M. Belzile, E. L. Gélinas, C. Trépanier, D. Émond, M. Gagnon, M. A. Bérubé, M. Int J Orthop Trauma Nurs 2023

Delirium, Early mobilization, Geriatric trauma, Mixed-methods, Pain management, Practice guidelines

Dose-dependent QTc interval prolongation under haloperidol and pipamperone in the management of delirium in a naturalistic setting Bohny, P. Boettger, S. Jenewein, J. Front Psychiatry 2023

QTc interval, delirium, haloperidol, pipamperone, torsades de pointes

Prevalence and risk factors of subsyndromal delirium among postoperative patients: A systematic review and meta-analysis Chen, S. Tang, L. Chen, J. Cai, L. Liu, C. Song, J. Chen, Y. Liu, Y. Zheng, S. J Adv Nurs 2023

Subsyndromal delirium, meta-analysis, nurse, nursing, postoperative care, prevalence, risk factors, surgery

Incidence change of postoperative delirium after implementation of processed electroencephalography monitoring during surgery: a retrospective evaluation study Chen, Y. C. Hung, I. Y. Hung, K. C. Chang, Y. J. Chu, C. C. Chen, J. Y. Ho, C. H. Yu, C. H. BMC Anesthesiol 2023

Humans
Aged
*Emergence Delirium/diagnosis/epidemiology/complications
Postoperative Complications/diagnosis/epidemiology/prevention & control
Incidence
Retrospective Studies
*Delirium/diagnosis/epidemiology/etiology
Anesthesia, General/adverse effects/methods
Electroencephalography
General anesthesia
Intravenous patient-controlled analgesia
Postoperative delirium
Processed electroencephalography

Incidence and risk factors for postoperative delirium after head and neck cancer surgery: an updated meta-analysis Dong, B. Yu, D. Jiang, L. Liu, M. Li, J. BMC Neurol 2023

Humans
Male
Aged
*Emergence Delirium/complications/epidemiology/prevention & control
*Delirium/epidemiology/etiology
Postoperative Complications/etiology
Incidence
Risk Factors
*Head and Neck Neoplasms/epidemiology/surgery
Head and neck cancer
Meta-analysis
Postoperative delirium
Systematic review

Five-year stroke prognosis. Influence of post-stroke delirium and post-stroke dementia on mortality and disability (Research Study - Part of the PROPOLIS Study) Droś, J. Segiet, N. Początek, G. Klimkowicz-Mrowiec, A. Neurol Sci 2023

Cognition disorders, Delirium, Dementia, Mortality, Stroke

Comparison of continuous sedatives in the burn ICU on delirium and coma Falksen, J. Young, S. R. Lee, J. A. J Burn Care Res 2023

burn, coma, delirium, sedation

Associations between depression symptom burden and delirium risk: a prospective cohort study Gaba, A. Li, P. Xi, Z. Gao, C. Ruixue, C. Hu, K. Gao, L. medRxiv 2023

Altered mental status
Alzheimer’s disease
anxiety
dementia
postoperative

Delirium and Previous Psychiatric History Independently Predict Poststroke Posttraumatic Stress Disorder Griffin, T. T. Bhave, V. McNulty, J. Christophe, B. R. Garton, A. L. A. Sander Connolly, E., Jr. Neurologist 2023

Humans, Female, *Stress Disorders, Post Traumatic/epidemiology/etiology/diagnosis, *Stroke/complications/epidemiology, *Delirium/diagnosis/epidemiology/etiology

Incidence of Postoperative Delirium in Cancer Patients After Head and Neck Surgery: A Proportional Meta-analysis Ho, M. H. Li, P. W. C. Lin, Y. K. Lee, J. J. Lin, C. C. Otolaryngol Head Neck Surg 2023

cancer, delirium, head and neck cancer, incidence, postoperative, proportional Meta-analysis

Triglyceride-glucose index as a valuable predictor for aged 65-years and above in critical delirium patients: evidence from a multi-center study Huang, X. Cheng, H. Yuan, S. Ling, Y. Tan, S. Tang, Y. Niu, C. Lyu, J. BMC Geriatr 2023

Humans
*Critical Care
Databases, Factual
Glucose
Triglycerides
*Delirium/diagnosis/epidemiology
Blood Glucose
Biomarkers
Risk Factors
Critical care
Delirium
Insulin resistance
Older adults
Triglyceride glucose index

Reliability and Validity of the Spanish Adaptation of the Stanford Proxy Test for Delirium in 2 Clinical Spanish-Speaking Communities Infante, S. Behn, A. González, M. Pintor, L. Franco, E. Araya, P. Maldonado, J. R. J Acad Consult Liaison Psychiatry 2023

Stanford proxy test for delirium, confusion assessment method, delirium, delirium and COVID, factor analysis

Association between preoperative neutrophil-lymphocyte ratio, uric acid, and postoperative delirium in elderly patients undergoing degenerative spine surgery Kato, K. Kinoshita, H. Kumagai, G. Takekawa, D. Nitobe, Y. Asari, T. Wada, K. Kushikata, T. Ishibashi, Y. Hirota, K. J Anesth 2023

Neuroprotection, Neutrophil–lymphocyte ratio, Postoperative delirium, Spine surgery, Uric acid

Preoperative assessment of postoperative delirium: a cross-sectional study of patients and anesthesiologists in Canada Khaled, M. Youssef, N. Choi, S. Uppal, V. Chui, J. Marcucci, M. Madden, K. Shanthanna, H. Can J Anaesth 2023

Humans
Male
Aged
Female
*Emergence Delirium
Cross-Sectional Studies
Anesthesiologists
*Delirium/diagnosis/epidemiology/complications
Canada
Risk Factors
Postoperative Complications/etiology
older adults
postoperative delirium
preoperative screening
risk reduction
shared decision-making

Resting-state prefrontal EEG biomarker in correlation with postoperative delirium in elderly patients Kim, J. Park, S. Kim, K. N. Ha, Y. Shin, S. J. Cha, W. Lee, K. Y. Choi, J. Koo, B. N. Front Aging Neurosci 2023

elderly, electroencephalography, median dominant frequency, postoperative complications, postoperative delirium

Risk of delirium with antiepileptic drug use: a study based on the Japanese Adverse Drug Event Report database Kubo, T. Sogawa, R. Tsuruhashi, S. Murakawa-Hirachi, T. Matsuoka, A. Mizoguchi, Y. Monji, A. Shimanoe, C. Int J Clin Pharm 2023

Humans
Anticonvulsants/adverse effects
Receptors, GABA-A
East Asian People
*Drug-Related Side Effects and Adverse Reactions
*Delirium/chemically induced/epidemiology/drug therapy
Adverse event
Antiepileptic drugs
Database
Delirium

Optimizing delirium care in the era of Age-Friendly Health System Kwak, M. J. Inouye, S. K. Fick, D. M. Bonner, A. Fulmer, T. Carter, E. Tabbush, V. Maya, K. Reed, N. Waszynski, C. Oh, E. S. J Am Geriatr Soc 2023

Age-Friendly Health System, Hospital Elder Life Program, delirium

Risk factors for hyperactive delirium after laparoscopic radical gastrectomy under general anesthesia in patients with gastric cancer Liu, J. Zhong, Q. Tan, H. Zhuo, M. Zhong, M. Cai, T. Am J Transl Res 2023

Laparoscopic radical gastrectomy, general anesthesia, hyperactive delirium, risk factors

Risk factors associated with postoperative delirium in elderly patients undergoing hip surgery Liu, X. H. Zhang, Q. F. Liu, Y. Lu, Q. W. Wu, J. H. Gao, X. H. Chen, Z. Y. Front Psychiatry 2023

Pacu
elderly retrospective study
hip surgery
postoperative delirium
prediction

The influence of delirium on mortality and length of ICU stay and analysis of risk factors for delirium after liver transplantation Ma, Y. Li, C. Peng, W. Wan, Q. ATS Sch 2023

ICU stay
delirium
liver transplantation
prognosis
risk factors

Hyperactive delirium during emergency department stay: analysis of risk factors and association with short-term outcomes Miró, Ò Osorio, G. Alquézar-Arbé, A. Aguiló, S. Fernández, C. Burillo, G. Jacob, J. Llorens, P. Llauger, L. Peláez González, Á Figuera Castro, E. R. Juarez González, R. Blanco Hoffman, M. J. Fernandez Salgado, F. Pablos Pizarro, T. Berenguer Dí Intern Emerg Med 2023

Benzodiazepines, Delirium, Emergency department, Mortality, Neuroleptics, Outcome

Delirium and neuropsychological recovery among emergency general surgery survivors (DANE): study protocol for a randomized controlled trial and collaborative care intervention Mohanty, S. Holler, E. Ortiz, D. Meagher, A. Perkins, A. Bylund, P. Khan, B. Unverzagt, F. Xu, H. Ingraham, A. Boustani, M. Zarzaur, B. Trials 2023

Humans
*Delirium/diagnosis/etiology/psychology
Treatment Outcome
Cognition
Consciousness
Randomized Controlled Trials as Topic
Multicenter Studies as Topic
Emergency general surgery
Postoperative delirium

A randomized, clinical trial investigating the use of a digital intervention to reduce delirium-associated agitation Nicholas, M. Wittmann, J. Norena, M. Ornowska, M. Reynolds, S. NPJ Digit Med 2023

delirium, agitation, digital, RASS

Cognitive Deficits in Executive and Language Functions Predict Postoperative Delirium Olotu, C. Lebherz, L. Ascone, L. Scherwath, A. Kühn, S. Härter, M. Kiefmann, R. J Cardiothorac Vasc Anesth 2023

Humans
Aged
*Emergence Delirium/diagnosis/epidemiology/etiology
*Delirium/diagnosis/epidemiology/etiology
Postoperative Complications/diagnosis/epidemiology/etiology
Prospective Studies
*Cognitive Dysfunction/diagnosis/epidemiology/etiology
Cognition/physiology
Risk Factors
anesthesia
neurocognitive disorders
older adults
postoperative delirium
preoperative assessment

Development of post-anesthesia care unit delirium is associated with differences in aperiodic and periodic alpha parameters of the EEG during emergence from general anesthesia - results from a prospective observational cohort study Ostertag, J. Engelhard, A. Nuttall, R. Aydin, D. Schneider, G. García, P. S. Hinzmann, D. Sleigh, J. W. Kratzer, S. Kreuzer, M. Anesthesiology 2023

PACU, delirium, EEG, hypnosis, alpha

Subsyndromal Delirium in Critically Ill Patients-Cognitive and Functional Long-Term Outcomes Paulino, M. C. Conceição, C. Silvestre, J. Lopes, M. I. Gonçalves, H. Dias, C. C. Serafim, R. Salluh, J. I. F. Póvoa, P. J Clin Med 2023

Icu, cognitive dysfunction delirium, long-term outcome, subsyndromal delirium

Prevalence of delirium in gastroenterology/hepatology units: A cross-sectional study Pazouki, R. Hasselblatt, P. Kugler, C. Z Gastroenterol 2023

Humans
Male
Middle Aged
Cross-Sectional Studies
*Delirium/diagnosis/epidemiology
Gastroenterology
*Liver Cirrhosis/complications
Prevalence
Female
Adult
Aged
Aged, 80 and over
*Hepatic Encephalopathy/complications

Grip Strength is a Predictor for Subsyndromal Delirium Among Older Adults Following Joint Replacement Qian, J. Shen, X. Gao, X. Sun, Q. Clin Interv Aging 2023

Aged
Female
Humans
Male
*Arthroplasty, Replacement
*Delirium/diagnosis/epidemiology/etiology
*Emergence Delirium
Postoperative Complications/diagnosis/epidemiology/etiology
Risk Factors
*Hand Strength
delirium
grip strength
joint replacement
risk factor
subsyndromal delirium

Prevalence and Risk Factors of Delirium in Patients Admitted to Intensive Care Units: A Multicentric Cross-Sectional Study Sadaf, F. Saqib, M. Iftikhar, M. Ahmad, A. Cureus 2023

critical illness, delirium, intensive care units, pakistan, prevalence

Perioperative Factors Associated With Postoperative Delirium in Patients Undergoing Noncardiac Surgery: An Individual Patient Data Meta-Analysis Sadeghirad, B. Dodsworth, B. T. Schmutz Gelsomino, N. Goettel, N. Spence, J. Buchan, T. A. Crandon, H. N. Baneshi, M. R. Pol, R. A. Brattinga, B. Park, U. J. Terashima, M. Banning, L. B. D. Van Leeuwen, B. L. Neerland, B. E. Chuan, A. Martinez, F. T. Van JAMA Netw Open 2023

Adult
Humans
*Emergence Delirium/epidemiology/etiology
*Delirium/epidemiology/etiology/diagnosis
Postoperative Complications/epidemiology/etiology/diagnosis
Risk Factors
Patients

Thirty-day mortality among patients with acute delirium in the emergency department Sanguanwit, P. Ninlamal, S. Prachanukool, T. Heliyon 2023

30-Day mortality, Delirium, Emergency department, Older-patients

Role of hypoxia-inducible factor in postoperative delirium of aged patients: A review Shen, H. Yang, J. Chen, X. Gao, Y. He, B. Medicine (Baltimore) 2023

Infant, Newborn, Humans, Aged, *Emergence Delirium, Transcription Factors/metabolism, Hypoxia, Ischemia, *Anesthetics, Hypoxia-Inducible Factor 1, alpha Subunit

The efficacy of earplugs and eye masks for delirium severity and sleep quality in patients undergoing coronary artery bypass grafting in cardiac intensive care units: A single-blind, randomised controlled trial Shorofi, S. A. Dadashian, P. Arbon, P. Moosazadeh, M. Aust Crit Care 2023

Coronary artery bypass grafting, Delirium, Earplugs, Eye masks, ICU psychosis, Sleep quality

Efficacy of haloperidol to decrease the burden of delirium in adult critically ill patients: the EuRIDICE randomized clinical trial Smit, L. Slooter, A. J. C. Devlin, J. W. Trogrlic, Z. Hunfeld, N. G. M. Osse, R. J. Ponssen, H. H. Brouwers, Ajbw Schoonderbeek, J. F. Simons, K. S. van den Boogaard, M. Lens, J. A. Boer, D. P. Gommers, Dampj Rietdijk, W. J. R. van der Jagt, M. Crit Care 2023

Adult
Humans
Male
Middle Aged
*Antipsychotic Agents/adverse effects
Coma
Critical Illness/therapy
*Delirium
Haloperidol
Intensive Care Units
Quality of Life
Female
Aged
Antipsychotic
Critical care
Delirium
Randomized controlled trial