Delirium Bibliography

Delirium Bibliography books graphicWhat is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!

How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.

Reference Information

Association Between Postoperative Delirium and Long-Term Subjective Cognitive Decline in Older Patients Undergoing Cardiac Surgery: A Secondary Analysis of the Minimizing Intensive Care Unit Neurological Dysfunction with Dexmedetomidine-Induced Sleep Tria
Namirembe, G. E. Baker, S. Albanese, M. Mueller, A. Qu, J. Z. Mekonnen, J. Wiredu, K. Westover, M. B. Houle, T. T. Akeju, O.
J Cardiothorac Vasc Anesth

OBJECTIVES: This study aimed to evaluate whether a measure of subjective cognitive decline (SCD), the Patient-Reported Outcomes Measurement Information System (PROMIS) Applied Cognition-Abilities questionnaire, was associated with postoperative delirium. It was hypothesized that delirium during the surgical hospitalization would be associated with a decrease in subjective cognition up to 6 months after cardiac surgery. DESIGN: This was a secondary analysis of data from the Minimizing Intensive Care Unit Neurological Dysfunction with Dexmedetomidine-induced Sleep randomized, placebo-controlled, parallel-arm superiority trial. SETTING: Data from patients recruited between March 2017 and February 2022 at a tertiary medical center in Boston, Massachusetts were analyzed in February 2023. PARTICIPANTS: Data from 337 patients aged 60 years or older who underwent cardiac surgery with cardiopulmonary bypass were included. INTERVENTIONS: Patients were assessed preoperatively and postoperatively at 30, 90, and 180 days using the subjective PROMIS Applied Cognition-Abilities and telephonic Montreal Cognitive Assessment. MEASUREMENT AND MAIN RESULTS: Postoperative delirium occurred within 3 days in 39 participants (11.6%). After adjusting for baseline function, participants who developed postoperative delirium self-reported worse cognitive function (mean difference [MD] -2.64 [95% CI -5.25, -0.04]; p = 0.047) up to 180 days after surgery, as compared with nondelirious patients. This finding was consistent with those obtained from objective t-MoCA assessments (MD -0.77 [95% CI -1.49, -0.04]; p = 0.04). CONCLUSIONS: In this cohort of older patients undergoing cardiac surgery, in-hospital delirium was associated with SCD up to 180 days after surgery. This finding suggested that measures of SCD may enable population-level insights into the burden of cognitive decline associated with postoperative delirium.


PMID: 37217424


cardiac surgery, cognition, delirium, postoperative, subjective cognitive decline


Total Records Found: 5967, showing 100 per page
Intraoperative body temperature and emergence delirium in elderly patients after non-cardiac surgery: A secondary analysis of a prospective observational study Wang, G. He, S. Yu, M. Zhang, Y. Mu, D. Wang, D. Chin Med J (Engl) 2023

Body Temperature
*Emergence Delirium
Postoperative Complications/epidemiology
Prospective Studies

Relationship between preoperative neutrophil-to-lymphocyte ratio and postoperative delirium: The PNDABLE and the PNDRFAP cohort studies Wu, X. Chi, F. Wang, B. Liu, S. Wang, F. Wang, J. Tang, X. Bi, Y. Lin, X. Li, J. Brain Behav 2023

Alzheimer-related biomarkers
risk factor

Risk Factors for Delirium Superimposed on Dementia in Elderly Patients in Comprehensive Ward Xiao, Q. Zhang, S. Li, C. Zhu, Y. Am J Alzheimers Dis Other Demen 2023

Retrospective Studies
*Alzheimer Disease/complications
Risk Factors
*Diabetes Mellitus
*Cerebrovascular Disorders
Superoxide Dismutase
Hypnotics and Sedatives
risk factor
senile dementia

Effect of postoperative delirium after cardiovascular surgery on 5-year mortality Yokoyama, C. Yoshitnai, K. Ogata, S. Fukushima, S. Matsuda, H. JA Clin Rep 2023

5-year mortality, Cardiopulmonary bypass, Cardiovascular surgery, Postoperative delirium

Association Between the Use of Midazolam During Cardiac Anesthesia and the Incidence of Postoperative Delirium: A Retrospective Cohort Study Using a Nationwide Database Yoshimura, M. Hidaka, Y. Morimoto, Y. J Cardiothorac Vasc Anesth 2023

Humans, *Emergence Delirium/epidemiology, Midazolam/adverse effects, Retrospective Studies, Incidence, Postoperative Nausea and, Vomiting/chemically induced/epidemiology, *Anesthesia, Cardiac Procedures, Postoperative, Complications/chemically induced/epidemiology, Diagnosis Procedure, Combination data, cardiac surgery, midazolam, postoperative delirium, stabilized inverse probability of treatment

Associations of Delirium to Posthospital Outcomes After Acute Stroke: A Scoping Review Young, B. C. Rhoten, B. A. J Neurosci Nurs 2023

Adult, Humans, Adolescent, *Dexmedetomidine/therapeutic use, Palliative Care, *Pain, Intractable/drug therapy/chemically induced, Hypnotics and, Sedatives/therapeutic use, Retrospective Studies, *Delirium/drug therapy, Intensive Care Units

Dexmedetomidine use for patients in palliative care with intractable pain and delirium: A retrospective study Yu, S. Y. Schellenberg, J. Alleyne, A. PLoS One 2023

Adult, Humans, Adolescent, *Dexmedetomidine/therapeutic use, Palliative Care, *Pain, Intractable/drug therapy/chemically induced, Hypnotics and, Sedatives/therapeutic use, Retrospective Studies, *Delirium/drug therapy, Intensive Care Units

Validity and predictability of the confusion assessment method for the intensive care unit for delirium among critically ill patients in the intensive care unit: A systematic review and meta-analysis Zhang, Y. Diao, D. Zhang, H. Gao, Y. Nurs Crit Care 2023

Cam-icu, critical, delirium, intensive care unit

Impact of nursing interventions on discharge disposition in patients with postoperative delirium Zhao, Y. Quon, A. Luke, K. Tivis, L. J. Nursing 2023

Humans, Aged, Patient Discharge, Retrospective Studies, *Emergence Delirium, *Hypoalbuminemia, Hospitalization

Causal relationships between delirium and Alzheimer's disease: a bidirectional two-sample Mendelian randomization study Zheng, J. Du, X. Yang, L. Fu, H. Eur J Med Res 2023

Humans, *Alzheimer Disease/genetics, Genome-Wide Association Study, Mendelian Randomization Analysis, Risk Factors, Nonoxynol, Alzheimer’s disease, Causal relationships, Delirium, European, Mendelian randomization

Circadian rhythm disturbance and delirium in ICU patients: a prospective cohort study Li, J. Cai, S. Liu, X. Mei, J. Pan, W. Zhong, M. Zhang, Y. Medicine (Baltimore) 2023

United States, Humans, *Hydrocortisone, *Melatonin, Prospective Studies, Circadian Rhythm, Intensive Care Units, Cortisol, Delirium, Melatonin

Amantadine-associated delirium in patients with maintenance dialysis: Insomnia-associated recovery and uneven seasonal distribution Li, J. Si, B. Chao, J. He, J. Medicine (Baltimore) 2023

Humans, Renal Dialysis, Retrospective Studies, Seasons, *Sleep Initiation and Maintenance Disorders/drug therapy, Amantadine/adverse effects, *Delirium/chemically induced/epidemiology

Effects of Different Injection Rates of Propofol on Postoperative Cognition in Elderly Patients Undergoing Laparoscopic Inguinal Hernia Repair Li, T. Han, W. Yang, X. Wang, Y. Peng, L. He, L. Hu, L. Liu, J. Xia, M. Wang, S. Drug Des Devel Ther 2023

Humans, Aged, *Propofol/adverse effects, Anesthetics, Intravenous/adverse effects, *Hernia, Inguinal/surgery/chemically induced, Postoperative, Complications/epidemiology, Cognition, *Delirium, *Laparoscopy, bispectral index, burst suppression, elderly, injection rate, postoperative cognitive decline, propofol

The Effect of Music as a Non-Pharmacological Intervention on the Physiological, Psychological, and Social Response of Patients in an Intensive Care Unit Lorek, M. Bąk, D. Kwiecień-Jaguś, K. Mędrzycka-Dąbrowska, W. Healthcare (Basel) 2023

classical music, delirium, intensive care unit, music perception, music therapy, nursing, pain, therapeutic music listening

Feasibility of a Modified Otago Exercise Program for Older Adults With Cognitive Vulnerability Mangione, K. K. Darreff, H. Welsh, M. Ni, W. Wolff, E. Booth, J. T. Glenney, S. S. Fortinsky, R. H. J Appl Gerontol 2023

Humans, Aged, Exercise Therapy, Feasibility Studies, Postural Balance, *Dementia/therapy, Cognition, *Delirium, Otago exercise program, dementia, depression, exercise, feasibility, older adult

Accuracy of Delirium Screening Tools in Older People with Cancer-A Systematic Review Martínez-Arnau, F. M. Puchades-García, A. Pérez-Ros, P. Cancers (Basel) 2023

accuracy, aged, assessment, cancer, delirium, incidence, prevalence, psychometric properties

Evaluation of the delirium preventive effect of dual orexin receptor antagonist (DORA) in critically ill adult patients requiring ventilation with tracheal intubation at an advanced emergency center: A single-center, retrospective, observational study Matsuoka, A. Sogawa, R. Murakawa-Hirachi, T. Mizoguchi, Y. Monji, A. Shimanoe, C. Shinada, K. Koami, H. Sakamoto, Y. J Alzheimers Dis 2023

Humans, Adult, Adolescent, *Orexin Receptor Antagonists/adverse effects, Retrospective Studies, Critical Illness/therapy, *Delirium/prevention & control/epidemiology, Intubation, Intratracheal, Delirium, Intensive care unit, Lemborexant, Sleep disorder, Suvorexant

Individualized Summary Assessment of Detailed Neuropsychological Testing for the Etiological Diagnosis of Newly Detected Cognitive Impairment in Hospitalized Geriatric Patients Mäurer, A. Himmel, G. Lange, C. Mathies, F. Apostolova, I. Peters, O. Buchert, R. J Alzheimers Dis 2023

Alzheimer’s disease, delirium, dementia, etiological diagnosis, hospitalized, geriatric patients, neuropsychological testing

A systematic review of studies reporting on neuropsychological and functional domains used for assessment of recovery from delirium in acute hospital patients McCartney, H. Noble, E. MacLullich, A. M. J. Davis, D. H. J. Evans, J. Shenkin, S. D. Muniz-Terrera, G. Sandeman, D. Tieges, Z. Int J Geriatr Psychiatry 2023

Humans, *Activities of Daily Living, *Delirium/diagnosis/drug therapy
Hospitals, 4at, delirium assessment, delirium recovery, functional recovery, longitudinal studies, neuropsychological domains, repeat assessment

Implementing a ward-based programme to improve care for older inpatients: process evaluation of the cluster randomised CHERISH trial Mudge, A. M. McRae, P. Young, A. Blackberry, I. Lee-Steere, K. Barrimore, S. Quirke, T. Harvey, G. BMC Health Serv Res 2023

Aged, Humans, *Delirium/prevention & control, Hospitals, *Inpatients, Nutritional Status, Prospective Studies, Age-friendly hospitals, Delirium, Evaluation, Facilitation, Implementation

Effect of laparoscopic liver resection on postoperative delirium in elderly patients with hepatocellular carcinoma Nomi, T. Kaibori, M. Hirokawa, F. Ueno, M. Hokuto, D. Noda, T. Nakai, T. Ikoma, H. Iida, H. Kubo, S. J Hepatobiliary Pancreat Sci 2023

elderly patients, hepatocellular carcinoma, laparoscopic liver resection, postoperative delirium

Development of a scale measuring the difficulties faced by nurses who care for patients with delirium in intensive care units Owaki, N. Tanaka, M. Kawakami, A. Aust Crit Care 2023

Humans, Reproducibility of Results, Pilot Projects, Intensive Care Units, Surveys and Questionnaires, *Delirium, *Nurses, Psychometrics/methods, Delirium, Exploratory factor analysis, Nurse, Psychological distress, Scale development

Preliminary evaluation of a smartphone application (DelApp) for identification of delirium in sub-Saharan Africa Paddick, S. M. Gamassa, E. Mwaluwinga, N. Lewis, G. Duinmaijer, A. Urasa, S. Tucker, L. Mukaetova-Ladinska, E. B. Cosker, G. Dekker, M. Kisoli, A. Cletus, J. Lissu, C. Dotchin, C. Gray, W. K. Walker, R. Acta Neuropsychiatr 2023

Africa, cognitive assessment, delirium, screening

Postoperative delirium after cholecystectomy in older patients: A retrospective study Park, Y. M. Seo, H. I. Noh, B. G. Kim, S. Hong, S. B. Lee, N. K. Kim, D. U. Han, S. Y. Ann Hepatobiliary Pancreat Surg 2023

Body mass index, Cholecystectomy, Delirium, Nutrition, Older patients

Exploring the Documentation of Delirium in Patients After Cardiac Surgery: A Retrospective Patient Record Study Poikajärvi, S. Peltonen, L. M. Siirala, E. Heimonen, J. Moen, H. Salanterä, S. Junttila, K. Comput Inform Nurs 2023

delirium, cardiac, surgery, EHR, documentation

The Efficacy of Low-Dose Risperidone Treatment for Post-Surgical Delirium in Elderly Orthopedic Patients Raphael, L. Edna, E. Irina, K. Oded, H. Medicina (Kaunas) 2023

Female, Humans, Aged, Aged, 80 and over, Male, Risperidone/adverse effects, Prospective Studies, *Delirium/drug therapy/etiology/diagnosis, *Orthopedics, Postoperative Complications/drug therapy, delirium, elderly, post-surgical, protocol, risperidone

Serum Biomarkers of a Pro-Neuroinflammatory State May Define the Pre-Operative Risk for Postoperative Delirium in Spine Surgery Ruhnau, J. Müller, J. Nowak, S. Strack, S. Sperlich, D. Pohl, A. Dilz, J. Saar, A. Veser, Y. Behr, F. Rehberg, S. Usichenko, T. Hahnenkamp, K. Ehler, J. Flöel, A. Schroeder, H. W. S. Müller, J. U. Fleischmann, R. Vogelgesang, A. Int J Mol Sci 2023

Humans, Aged, *Emergence Delirium, Interleukin-6/metabolism, *Delirium/diagnosis/etiology, Gasdermins, Postoperative, Complications/etiology, Prospective Studies, Biomarkers/metabolism, Gasdermin D, biomarker, postoperative cognitive dysfunction, postoperative delirium, sTREM2, spine surgery

Effects of an interactive handgrip game on surgical patients requiring intensive care: An assessor-blinded randomized controlled trial Han, P. H. Shih, C. Y. Wang, A. Y. Chen, Y. C. Yang, C. C. Fan, Y. C. Hsiang, H. F. Chiu, H. Y. Intensive Crit Care Nurs 2023

Critically ill patients, Handgrip strength, Interactive handgrip game, Psychological distress

A critical appraisal and recommendation synthesis of delirium clinical practice guidelines relevant to the care of older adults in the emergency department: An umbrella review Filiatreault, S. Grimshaw, J. M. Kreindler, S. A. Chochinov, A. Linton, J. Chatterjee, R. Azeez, R. Doupe, M. B. J Eval Clin Pract 2023

Agree, aged, delirium, emergency services (hospital), practice guideline, systematic review

Implementation of a novel nursing assessment tool in geriatric trauma patients with proximal femur fractures Berk, T. Thalmann, M. Jensen, K. O. Schwarzenberg, P. Jukema, G. N. Pape, H. C. Halvachizadeh, S. PLoS One 2023

Humans, Aged, Retrospective Studies, *Proximal Femoral Fractures, *Delirium/etiology/complications, Risk Factors, Nutritional Status, Geriatric Assessment

Enhanced recovery after surgery in patients with normal pressure hydrocephalus undergoing ventriculoperitoneal shunting procedures Ali, A. Gupta, B. Johansen, P. Santiago, R. B. Dabecco, R. Mandel, M. Adada, B. Botero, J. Roy, M. Borghei-Razavi, H. Clin Neurol Neurosurg 2023

Humans, Ventriculoperitoneal Shunt/adverse effects, *Hydrocephalus, Normal Pressure/surgery/complications, *Enhanced Recovery After Surgery, Postoperative Complications/etiology, *Delirium/complications/surgery, Length of Stay, Retrospective Studies, Delirium, Eras, Neurosurgery, Normal pressure hydrocephalus, Ventriculoperitoneal shunting

The use of patient sitters at a Swiss hospital: A retrospective observational study Kramer, I. Schubert, M. PLoS One 2023

Aged, Humans, Confusion, *Ethnicity, Hospitals, *Inpatients, Retrospective Studies, Switzerland, Aged, 80 and over

The role of inflammatory parameters in the prediction of postoperative delirium in patients undergoing coronary artery bypass grafting Şaşkin, H. Özcan, K. S. Yildirim, S. Cardiovasc J Afr 2023

Humans, *Emergence Delirium/etiology, Retrospective Studies, Postoperative Complications/diagnosis/etiology, Coronary Artery Bypass/adverse effects, Risk Factors, coronary artery bypass grafting surgery, delirium, inflammation

Opioids increase the risk of delirium in critically ill patients: A propensity score analysis Shi, H. J. Zhang, X. P. Hai, C. Shi, W. Wang, P. Hu, A. M. Int J Clin Pharmacol Ther 2023

Humans, *Analgesics, Opioid/adverse effects, Intensive Care Units, Critical, Illness/therapy, Propensity Score, Risk Factors, *Delirium/chemically induced/diagnosis/epidemiology

Characteristics of delirium and its association with sedation and in-hospital mortality in patients with COVID-19 on veno-venous extracorporeal membrane oxygenation Sun, P. Y. Fanning, J. Peeler, A. Shou, B. Lindsley, J. Caturegli, G. Whitman, G. Cha, S. Kim, B. S. Cho, S. M. Front Med (Lausanne) 2023

analgesia, deep sedation, delirium, extracorporeal membrane oxygenation, hospital mortality

Delirium as a Risk Factor for Mortality in Critically Ill Patients With Cancer Tao, J. Seier, K. Marasigan-Stone, C. B. Simondac, J. S. Pascual, A. V. Kostelecky, N. T. SantaTeresa, E. Nwogugu, S. O. Yang, J. J. Schmeltz, J. Tan, K. S. Chawla, S. Voigt, L. P. JCO Oncol Pract 2023

Humans, Female, Middle Aged, Aged, Male, *Delirium/diagnosis/prevention & control, Critical Illness, Risk Factors, Intensive Care Units, *Neoplasms

Effectiveness of sleep interventions to reduce delirium in critically ill patients: A systematic review and meta-analysis Teng, J. Qin, H. Guo, W. Liu, J. Sun, J. Zhang, Z. J Crit Care 2023

Critical illness, Delirium, ICUs, Meta-analysis, Sleep

Chlorpromazine's Potential Role in Palliating Distressing Symptoms Associated With Hyperactive Delirium in Patients at End of Life Tiefenthaler, C. M. Hirst, J. M. Edmonds, K. P. Atayee, R. S. J Palliat Med 2023

Humans, Chlorpromazine/therapeutic use, Psychomotor Agitation/drug therapy/complications/prevention & control, *Delirium/drug therapy, *Neoplasms/complications, Death, Palliative Care, chlorpromazine
end of life, hyperactive delirium, proportionate sedation

Delirium and IL-6 added to clinical scores improves their performance: a prospective analysis of CALL, PREDI-CO, MRS score applied to a population of patients admitted to internal medicine ward Vannucchi, V. Pelagatti, L. Barone, F. Bertini, L. Celli, T. Boccia, N. Veneziani, F. Cimolato, B. Landini, G. Intern Emerg Med 2023

Call, Covid-19, Delirium,il-6, Mrs, Outcome, Predi-co, Score

Electroencephalographic Biomarkers, Cerebral Oximetry, and Postoperative Cognitive Function in Adult Non-Cardiac Surgical Patients: a Prospective Cohort Study Vlisides, P. E. Li, D. Maywood, M. Zierau, M. Lapointe, A. P. Brooks, J. McKinney, A. M. Leis, A. M. Mentz, G. Mashour, G. A. Anesthesiology 2023

Adult, Humans, Retrospective Studies, Prospective Studies, *Delirium/diagnosis/epidemiology/etiology, Critical Illness, Intensive Care Units, Critically ill, Delirium, Intensive care unit, Machine learning, Prediction

Early prediction of delirium upon intensive care unit admission: Model development, validation, and deployment Wang, M. L. Kuo, Y. T. Kuo, L. C. Liang, H. P. Cheng, Y. W. Yeh, Y. C. Tsai, M. T. Chan, W. S. Chiu, C. T. Chao, A. Chou, N. K. Yeh, Y. C. Ku, S. C. J Clin Anesth 2023

Adult, Humans, Retrospective Studies, Prospective Studies, *Delirium/diagnosis/epidemiology/etiology, Critical Illness, Intensive Care Units, Critically ill, Delirium, Intensive care unit, Machine learning, Prediction

Perioperative cerebral perfusion in aortic arch surgery: a potential link with neurological outcome Weijs, R. W. J. Tromp, S. C. Heijmen, R. H. Seeber, A. A. van Belle-van Haaren, Njcw Claassen, Jahr Thijssen, D. H. J. Eur J Cardiothorac Surg 2023

Humans, Aorta, Thoracic/diagnostic imaging/surgery, *Brain Ischemia/etiology/prevention & control, Retrospective Studies, *Stroke/etiology/prevention & control, Perfusion, *Ischemic Stroke, Cerebrovascular Circulation/physiology, *Delirium, Treatment Outcome, Postoperative Complications/prevention & control, *Aortic Aneurysm, Thoracic/surgery, Antegrade selective cerebral perfusion, Aortic surgery, Cerebral circulation, Perioperative management, Postoperative complication, Thoracic aorta

Preoperative Cognitive Impairment and Postoperative Delirium in Elderly Surgical Patients: A Retrospective Large Cohort Study (The CIPOD Study) Weiss, Y. Zac, L. Refaeli, E. Ben-Yishai, S. Zegerman, A. Cohen, B. Matot, I. Ann Surg 2023

Humans, Aged, *Emergence Delirium/complications, *Delirium/diagnosis/epidemiology/etiology, Retrospective Studies, Cohort Studies, Prospective Studies, *Cognitive Dysfunction/diagnosis/epidemiology, Postoperative Complications/etiology, Risk Factors

Contribution of Different Brain Disorders and Multimorbidity to Delirium Superimposed Dementia (DSD) Wetterling, T. Junghanns, K. Geriatrics (Basel) 2023

brain infarction, deliriumm dementia, multimorbidity, white matter hyperintensities

Prevalence and Risk Factors for Intensive Care Unit Delirium After Traumatic Brain Injury: A Retrospective Cohort Study Wilson, L. D. Maiga, A. W. Lombardo, S. Nordness, M. F. Haddad, D. N. Rakhit, S. Smith, L. F. Rivera, E. L. Cook, M. R. Thompson, J. L. Raman, R. Patel, M. B. Neurocrit Care 2023

Adult, Humans, Retrospective Studies, Prevalence, *Brain Injuries,, Traumatic/complications/epidemiology, Risk Factors, Intensive Care Units, *Subarachnoid Hemorrhage/complications, *Delirium/epidemiology/etiology, Glasgow Coma Scale,Critical illness, Delirium, Mental status, Predictors, Traumatic brain injury

Moderate-to-high risk of obstructive sleep apnea with excessive daytime sleepiness is associated with postoperative neurocognitive disorders: a prospective one-year follow-up cohort study Wu, W. Pu, L. Hu, X. Chen, Q. Wang, G. Wang, Y. Front Neurosci 2023

excessive daytime sleepiness, obstructive sleep apnea, older adults, perioperative neurocognitive disorders, surgery

Effect of Dexmedetomidine on Posttraumatic Stress Disorder in Patients Undergoing Emergency Trauma Surgery: A Randomized Clinical Trial Yu, Y. Li, Y. Han, D. Gong, C. Wang, L. Li, B. Yao, R. Zhu, Y. JAMA Netw Open 2023

Male, Humans, Adult, *Dexmedetomidine/therapeutic use/adverse effects, *Stress Disorders, Post-Traumatic/epidemiology/prevention & control, Saline Solution, *Emergence Delirium/chemically induced, Administration, Intravenous

Regional versus general anesthesia in older patients for hip fracture surgery: a systematic review and meta-analysis of randomized controlled trials Zhou, S. L. Zhang, S. Y. Si, H. B. Shen, B. J Orthop Surg Res 2023

Humans, Aged, Randomized Controlled Trials as Topic, *Hip Fractures/surgery, Anesthesia, General/adverse effects, *Plastic Surgery Procedures, *Delirium, Anesthesia, General, Hip fracture, Meta-analysis, Regional

Delirium in Medically Hospitalized Patients: Prevalence, Recognition and Risk Factors: A Prospective Cohort Study Al Farsi, R. S. Al Alawi, A. M. Al Huraizi, A. R. Al-Saadi, T. Al-Hamadani, N. Al Zeedy, K. Al-Maqbali, J. S. J Clin Med 2023

delirium, elderly, incidence, prevalence, risk factors

Delirium detection using wearable sensors and machine learning in patients with intracerebral hemorrhage Ahmed, A. Garcia-Agundez, A. Petrovic, I. Radaei, F. Fife, J. Zhou, J. Karas, H. Moody, S. Drake, J. Jones, R. N. Eickhoff, C. Reznik, M. E. Front Neurol 2023

actigraphy, delirium, intracerebral hemorrhage, machine learning, neurocritical care, stroke, wearable electronic devices

Associations of postoperative delirium with activities of daily living in older people after major surgery: A prospective cohort study Aldwikat, R. K. Manias, E. Holmes, A. C. Tomlinson, E. Nicholson, P. J Clin Nurs 2023

activities of daily living, cognition, older surgical patients, post-anaesthetic care unit, postoperative delirium

Association Between Risk of Stroke and Delirium After Cardiac Surgery and a New Electroencephalogram Index of Interhemispheric Similarity Baron Shahaf, D. Hight, D. Kaiser, H. Shahaf, G. J Cardiothorac Vasc Anesth 2023

Eeg, Lir, delirium, stroke

Melatonin and Ramelteon for the treatment of delirium: A systematic review and meta-analysis Beaucage-Charron, J. Rinfret, J. Coveney, R. Williamson, D. J Psychosom Res 2023

Humans, Aged, *Melatonin/therapeutic use, *Delirium/drug therapy, *Indenes/therapeutic use, *Antipsychotic Agents/therapeutic use, Delirium, Melatonergic agonist, Melatonin, Ramelteon, Treatment

A Core Outcome Set for Interventions to Prevent and/or Treat Delirium in Palliative Care Bryans, A. Siddiqi, N. Burry, L. Clarke, M. Koffman, J. Agar, M. R. Rose, L. J Pain Symptom Manage 2023

Delirium, clinical trials, core outcome set, palliative care

Delirium in the Era of COVID-19 Byrnes, T. Pate, K. Cochran, A. R. Belin, L. J Nurs Care Qual 2023

delirium, covid-19, older adults,

Leveraging the Electronic Health Record to Implement Emergency Department Delirium Screening Chary, A. N. Brickhouse, E. Torres, B. Santangelo, I. Carpenter, C. R. Liu, S. W. Godwin, K. M. Naik, A. D. Singh, H. Kennedy, M. Appl Clin Inform 2023

Humans, Aged, *Electronic Health Records, Emergency Service, Hospital, Attitude of Health Personnel, *Delirium/diagnosis

Cigarette smoking is linked to an increased risk of delirium following arthroplasty in patients suffering from osteoarthritic pain Chen, J. R. Chen, J. Q. Hu, J. C. Huang, R. S. Shen, L. Gu, H. Chai, X. Q. Wang, D. CNS Neurosci Ther 2023

osteoarthritis, postoperative delirium, smoking, total knee arthroplasty

Neurological Examination Frequency and Time-to-Delirium After Traumatic Brain Injury Chotai, S. Chen, J. W. Turer, R. Smith, C. Kelly, P. D. Bhamidipati, A. Davis, P. McCarthy, J. T. Bendfeldt, G. A. Peyton, M. B. Dennis, B. M. Terry, D. P. Guillamondegui, O. Yengo-Kahn, A. M. Neurosurgery Neurological Examination Frequency and Time-to-Delirium After Traumatic Brain Injury

neurological, traumatic brain injury, delirium, time-to-delirium, ICU, CAM-ICU

Effect of inhaled anaesthetics on cognitive and psychiatric outcomes in critically ill adults: a systematic review and meta-analysis Cuninghame, S. Jerath, A. Gorsky, K. Sivajohan, A. Francoeur, C. Withington, D. Burry, L. Cuthbertson, B. H. Orser, B. A. Martin, C. Owen, A. M. Slessarev, M. Br J Anaesth 2023

cognition, critical care medicine, delirium, post-ICU syndrome, psychiatric, sedation

The Delirium Interview as a new reference standard in studies on delirium assessment tools Ditzel, F. L. Slooter, A. J. C. van den Boogaard, M. Boonstra, M. van Nesselrooij, T. A. Kromkamp, M. Pop-Purceleanu, M. Rood, P. J. T. Osse, R. J. Chan, C. K. MacLullich, A. M. J. Tieges, Z. Neufeld, K. J. Hut, S. C. A. J Am Geriatr Soc 2023

Humans, Male, Aged, Aged, 80 and over, Female, Prospective Studies, *Intensive Care Units, *Delirium/diagnosis, Critical Care, Reference Standards, cognitive assessment, delirium, neuropsychological tests, reference standard

Development and validation of an international preoperative risk assessment model for postoperative delirium Dodsworth, B. T. Reeve, K. Falco, L. Hueting, T. Sadeghirad, B. Mbuagbaw, L. Goettel, N. Schmutz Gelsomino, N. Age Ageing 2023

Humans, Aged, *Emergence Delirium/complications, *Delirium/diagnosis/etiology/prevention & control, Risk Factors, Postoperative Complications/diagnosis/etiology/prevention & control, Risk Assessment, C-Reactive Protein, algorithm, clinical practice, older people, postoperative delirium, risk prediction

Emergency Department Length of Stay Is Associated with Delirium in Older Adults Elder, N. M. Mumma, B. E. Maeda, M. Y. Tancredi, D. J. Tyler, K. R. West J Emerg Med 2023

Humans, Female, Aged, Male, Length of Stay, Retrospective Studies, *Delirium/epidemiology, Prospective Studies, Risk Factors, Emergency Service, Hospital, *Dementia

'It's tough. It is hard': A qualitative interview study of staff and volunteers caring for hospice in-patients with delirium Featherstone, I. Siddiqi, N. Jones, L. Coppo, E. Sheldon, T. Hosie, A. Wolkowski, A. Bush, S. H. Taylor, J. Teodorczuk, A. Johnson, M. J. Palliat Med 2023

Humans, *Hospices, Palliative Care/psychology, *Hospice Care, Qualitative Research, Volunteers, *Delirium/therapy, Delirium, hospices, palliative care, psychological distress, qualitative research

Metabolic syndrome and the risk of postoperative delirium and postoperative cognitive dysfunction: a multi-centre cohort study Feinkohl, I. Janke, J. Slooter, A. J. C. Winterer, G. Spies, C. Pischon, T. Br J Anaesth 2023

cholesterol, epidemiology, metabolic syndrome, obesity, postoperative cognitive dysfunction, postoperative delirium

Delirium After Traumatic Brain Injury: Prediction by Location and Size of Brain Lesion Han, S. J. Suh, J. H. Lee, J. Y. Kim, S. J. Ann Rehabil Med 2023

Delirium, Intracranial hemorrhages, Traumatic brain injury

Meta-analysis of the effect of entropy-assisted general anesthesia on the quality of postoperative recovery He, B. Zhang, N. Peng, M. Medicine (Baltimore) 2023

Humans, Postoperative Nausea and Vomiting/epidemiology/prevention & control, *Emergence Delirium, Entropy, *Intraoperative Awareness, Anesthesia, General/adverse effects, Randomized Controlled Trials as Topic

Sex-specific clinical characteristics and treatment responses in delirium management: findings from a prospective cohort study in elderly patients Hildenbrand, F. F. Boettger, S. Spiller, T. Schubert, M. Ernst, J. von Känel, R. Zipser, C. M. Int Clin Psychopharmacol 2023

delirium, incidence, sex differences, observational, elderly

A predictive scoring system for postoperative delirium in the elderly patients with intertrochanteric fracture Hu, Y. Yang, M. BMC Surg 2023

Humans, Aged, Infant, Retrospective Studies, *Emergence Delirium/etiology, *Fracture Fixation, Intramedullary/adverse effects, Treatment Outcome, *Hip, Fractures/complications/surgery, *Stroke/etiology, Elderly, Intertrochanteric fracture, Postoperative delirium, Prediction, Reduction and internal fixation, Scoring system

A single preoperative low-dose dexamethasone may reduce the incidence and severity of postoperative delirium in the geriatric intertrochanteric fracture patients with internal fixation surgery: an exploratory analysis of a randomized, placebo-controlled t Huang, J. W. Yang, Y. F. Gao, X. S. Xu, Z. H. J Orthop Surg Res 2023

Humans, Aged, *Emergence Delirium/drug therapy, Postoperative, Complications/epidemiology/etiology/prevention & control, Prospective Studies
Incidence, *Delirium/epidemiology/etiology/prevention & control, *Hip Fractures/surgery/drug therapy, Dexamethasone, Intertrochanteric fractures, Postoperative delirium, The elderly

Incidence of postoperative delirium in older adults undergoing surgical procedures: A systematic literature review and meta-analysis Igwe, E. O. Nealon, J. O'Shaughnessy, P. Bowden, A. Chang, H. R. Ho, M. H. Montayre, J. Montgomery, A. Rolls, K. Chou, K. R. Chen, K. H. Traynor, V. Smerdely, P. Worldviews Evid Based Nurs 2023

Humans, Aged, *Emergence Delirium/complications, *Delirium/epidemiology/etiology/diagnosis, Postoperative, Complications/epidemiology/etiology, Incidence, Risk Factors, meta-analysis
older people, postoperative delirium, systematic review

Music to prevent deliriUm during neuroSurgerY (MUSYC): a single-centre, prospective randomised controlled trial Kappen, P. R. Mos, M. I. Jeekel, J. Dirven, C. M. F. Kushner, S. A. Osse, R. J. Coesmans, M. Poley, M. J. van Schie, M. S. van der Holt, B. Klimek, M. Vincent, Ajpe BMJ Open 2023

Adult, Humans, *Music, *Neurosurgery, Prospective Studies, *Delirium/etiology/prevention & control/diagnosis, Neurosurgical, Procedures/adverse effects, clinical trials, complementary medicine, delirium & cognitive disorders, neurosurgery, preventive medicine

Intraoperative suggestions to prevent postoperative delirium in patients undergoing transaortic valvular replacement: a randomized placebo-controlled trial Kaufmann, C. Zech, N. Brandt, F. Hilker, M. Debl, K. Creutzenberg, M. Zeman, F. Graf, B. M. Sinner, B. Aging Clin Exp Res 2023

Intraoperative suggestions, Postoperative delirium, Transcatheter aortic valve replacement

Association of cervical atherosclerosis on Doppler ultrasonography and postoperative delirium in patients undergoing spinal surgery: a single-center, retrospective, observational study Kumagai, G. Wada, K. Asari, T. Nitobe, Y. Kinoshita, H. Kushikata, T. Hirota, K. Ishibashi, Y. Eur Spine J 2023

Cervical atherosclerosis, Older age, Postoperative delirium, Spinal surgery, Ultrasonography

Educational intervention for family caregivers of older adults with delirium: An integrative review Lee, J. Yeom, I. Yoo, S. Hong, S. J Clin Nurs 2023

education, family, older patients, review

The presence of preoperative neurodegeneration biofluid markers in patients with postoperative delirium Leung, J. M. Rojas, J. C. Tang, C. Chan, B. Lario-Lago, A. Boxer, A. L. Do, Q. Kramer, J. H. Du, Z. Du, P. Sands, L. P. Anesthesiology 2023

postoperative delirium, surgical, neurodegeneration, confusion assessment method, biomarkers

Visual Dysfunction is a Risk Factor of Post-operation Delirium in Parkinson's Disease Li, C. Lian, C. Wu, Q. Q. Hou, Y. Zhao, W. B. Wang, X. Zhang, C. World Neurosurg 2023

Dbs, Pod, Parkinson ’s disease, Visual impairment

Relationship between in-hospital angiotensin converting enzyme inhibitors and Angiotensin receptor blockers administration and delirium in the cardiac ICU Mulkey, M. A. Hauser, P. H. P. Aucoin, J. Hosp Pract (1995) 2023

ACE inhibitor, Angiotensin receptor blocker, Antihypertensives, cardiac intensive care unit, delirium

Predictors of cognitive impairment in patients undergoing ileostomy for colorectal cancer: a retrospective analysis Xu, J. Yang, Y. Hu, D. PeerJ 2023

Humans, Retrospective Studies, Ileostomy, Quality of Life, *Cognitive, Dysfunction/diagnosis, *Postoperative Cognitive Complications, *Delirium
*Colorectal Neoplasms/surgery, Clinical predictive models, Cognitive impairment, Postoperative, Retrospective analysis

The effect of music therapy on delirium in patients receiving mechanical ventilatory support in the Intensive Care Unit: A protocol for systematic review and meta-analysis Zhou, C. Ma, H. Qi, X. Xu, C. Liang, Z. Medicine (Baltimore) 2023

Humans, *Delirium/drug therapy, Intensive Care Units, *Meta-Analysis as Topic, *Music Therapy, *Systematic Reviews as Topic/methods

Incidence of and risk factors for post-intensive care syndrome among Chinese respiratory intensive care unit patients: A cross-sectional, prospective study Zhou, M. Zhang, J. Xu, Z. Gu, H. Chen, Z. Ding, Y. Aust Crit Care 2023

Humans, Prospective Studies, Incidence, *Quality of Life, Cross-Sectional Studies, *Activities of Daily Living, East Asian People, Intensive Care Units, Risk Factors, Effect factors, Patients, Post–intensive care syndrome, Respiratory intensive care unit

The Impact of an Educational Programme on Jordanian Intensive Care Nurses' Knowledge, Attitudes, and Practice Regarding Delirium and their Levels of Self-Efficacy: A Quasi-Experimental Design Alhalaiqa, F. Masa'Deh, R. Al Omari, O. Shawashreh, A. Khalifeh, A. H. Gray, R. Iran J Nurs Midwifery Res 2023

Attitude, delirium, education, intensive care units, knowledge, self efficacy

Nonpharmacological interventions for agitation in the adult intensive care unit: A systematic review Adams, A. M. N. Chamberlain, D. Grønkjær, M. Brun Thorup, C. Conroy, T. Aust Crit Care 2023

Adult, Humans, Intensive Care Units, Psychomotor Agitation/therapy, Critical care, Delirium, Intensive care unit, Nonpharmacological interventions, Nursing, Psychomotor agitation, Systematic review

Postoperative Outcomes in Elderly Patients Undergoing Cardiac Surgery With Preoperative Cognitive Impairment: A Systematic Review and Meta-Analysis Au, E. Thangathurai, G. Saripella, A. Yan, E. Englesakis, M. Nagappa, M. Chung, F. Anesth Analg 2023

Human, Aged, Delirium/etiology/complications, Cognitive, Dysfunction/complications, Postoperative Complications/diagnosis/etiology, Cardiac Surgical Procedures/adverse effect, Intensive Care Units

The prediction of postoperative delirium with the preoperative bispectral index in older aged patients: a cohort study Bao, L. Liu, T. Zhang, Z. Pan, Q. Wang, L. Fan, G. Li, Z. Yin, Y. Aging Clin Exp Res 2023

Bis, Elderly patients, Monitoring, Postoperative delirium, Prediction, Preoperative predictive score

Insulin resistance, age and depression's impact on cognition in middle-aged adults from the PREVENT cohort Bauermeister, S. D. Ben Yehuda, M. Reid, G. Howgego, G. Ritchie, K. Watermeyer, T. Gregory, S. Terrera, G. M. Koychev, I. BMJ Ment Health 2023

Middle Aged, Humans, Adult, Aged, Diabetes Mellitus, Type 2/epidemiology, Insulin Resistance, Depression/epidemiology, Cohort Studies, Cross-Sectional Studies, Cognition, Alzheimer Disease/psychology, delirium & cognitive disorders, depression & mood disorders, psychiatry

Key elements of an evidence-based clinical psychology service within adult critical care Beadman, M. Carraretto, M. J Intensive Care Soc 2023

Psychology, critical care, delirium, follow-up clinics, post-intensive care syndrome

Neurofilament light chains to assess sepsis-associated encephalopathy: Are we on the track toward clinical implementation? Bircak-Kuchtova, B. Chung, H. Y. Wickel, J. Ehler, J. Geis, C. Crit Care 2023

Humans, Sepsis-Associated Encephalopathy/complications/diagnosis, Intermediate Filaments, Sepsis/complications/diagnosis, Biomarkers, Brain Diseases, Biomarker, Brain dysfunction, Delirium, Encephalopathy, Neurofilament light chain, Sae, Sepsis

Veterans' experiences of moral injury, treatment and recommendations for future support Bonson, A. Murphy, D. Aldridge, V. Greenberg, N. Williamson, V. BMJ Mil Health 2023

anxiety disorders, delirium & cognitive disorders, depression & mood disorders, public health

General Anesthesia Versus Regional Anesthesia in the Elderly Patients Undergoing Hip Fracture Surgeries: A Systematic Review and Meta-Analysis of Randomized Clinical Trials Cao, M. M. Zhang, Y. W. Sheng, R. W. Gao, W. Kang, Q. R. Gao, Y. C. Qiu, X. D. Rui, Y. F. World J Surg 2023

Humans, Aged, Emergence Delirium, Blood Loss, Surgical/prevention & control, Postoperative Complications/epidemiology/etiology, Randomized Controlled Trials as Topic, Anesthesia, General, Anesthesia, Conduction, Hip Fractures/surgery

Delirium in ventilated patients receiving fentanyl and morphine for Analgosedation: Findings from the ANALGESIC trial Casamento, A. Neto, A. S. Lawrence, M. Chudleigh, L. Browne, E. Taplin, C. Eastwood, G. M. Bellomo, R. J Crit Care 2023

Analgosedation, Delirium, Mechanical ventilation, Opioids

Postoperative delirium after intracranial neurosurgery: A prospective cohort study from a developing nation Chakrabarti, D. Bharadwaj, S. Akash, V. S. Wadhwa, A. Konar, S. Kamath, S. Gopalakrishna, K. N. Acta Neurochir (Wien) 2023

Humans, Emergence Delirium/complications, Delirium/epidemiology/etiology
Prospective Studies, Neurosurgery, Developing Countries, Postoperative Complications/epidemiology/etiology, Anesthesia, Delirium, Neurosurgery, Postoperative

Incidence of preoperative instrumental activities of daily living (IADL) dependence and adverse outcomes in older surgical patients: A systematic review and meta-analysis Chen, A. An, E. Yan, E. He, D. Saripella, A. Butris, N. Tsang, J. Englesakis, M. Wong, J. Alibhai, S. Chung, F. J Clin Anesth 2023

Delirium, systematic review and meta-analysis, Functional dependence,, Instrumental activities of daily living (IADL), Older patients, Preoperative assessment

Heterogeneity in the definition of delirium in ICUs and association with the intervention effect in randomized controlled trials: a meta-epidemiological study Collet, L. Lanore, A. Alaterre, C. Constantin, J. M. Martin, G. L. Caille, A. James, A. Dechartres, A. Crit Care 2023

Humans, Delirium/diagnosis/epidemiology/therapy, Epidemiologic Studies, Intensive Care Units, Randomized Controlled Trials as Topic, Meta-Analysis as Topic, Definition, Delirium, Heterogeneity, Intensive care, Meta-analysis, Meta-epidemiology

A prospective multicentre observational study to quantify nocturnal light exposure in intensive care Craig, T. Mathieu, S. Morden, C. Patel, M. Matthews, L. J Intensive Care Soc 2023

Light, circadian rhythm, delirium, environment, light pollution

Recognizing and Reducing Delirium in the Intensive Care Unit Dechant, T. Smith, L. Chavez, J. Crit Care Nurs Q 2023

Humans, Disease Progression, Intensive Care Units
Quality Improvement, Delirium/diagnosis/prevention & control

Postoperative Deep Sedation after Microvascular Reconstructive Surgery for Oral Cancer Increases the Risk of Early Postoperative Pneumonia Fukuzawa, S. Yamagata, K. Takaoka, S. Uchida, F. Ishibashi-Kanno, N. Yanagawa, T. Bukawa, H. Dent J (Basel) 2023

oral cancer, postoperative delirium, postoperative pneumonia, postoperative sedation, reconstructive surgery

Heart rate response and recovery during exercise predict future delirium risk-A prospective cohort study in middle- to older-aged adults Gao, L. Gaba, A. Li, P. Saxena, R. Scheer, Fajl Akeju, O. Rutter, M. K. Hu, K. J Sport Health Sci 2023

Male, Humans, Adult, Middle Aged, Female, Heart Rate/physiology, Prospective Studies, Exercise/physiology, Risk Factors, Delirium, Brain health, Delirium, Exercise stress test

Circadian Rest-Activity Rhythms, Delirium Risk, and Progression to Dementia Gao, L. Li, P. Gaykova, N. Zheng, X. Gao, C. Lane, J. M. Saxena, R. Scheer, Fajl Rutter, M. K. Akeju, O. Hu, K. Ann Neurol 2023

Middle Aged, Humans, Sleep, Circadian Rhythm, Rest, Actigraphy, Sleep Wake Disorders, Dementia/etiology, Delirium/etiology

Frequency and Risk Factors of Subsyndromal Delirium in the Intensive Care Units: A Prospective Cohort Study Gao, Y. Gong, S. Zhou, W. Li, X. Gan, X. Neuropsychiatr Dis Treat 2023

Icu, intensive care units, prevalence, risk factors, subsyndromal delirium

Calibration of the PREdiction of DELIRium in ICu Patients (PRE-DELIRIC) Score in a Cohort of Critically Ill Patients: A Retrospective Cohort Study Gravante, F. Giannarelli, D. Pucci, A. Pisani, L. Latina, R. Dimens Crit Care Nurs 2023

Humans, Calibration, Critical Illness, Retrospective Studies, Nonoxynol, Delirium, Intensive Care Units