What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Longitudinal Profiling of Plasma Cytokines and Its Association With Postoperative Delirium in Elderly Patients Undergoing Major Lower Limb Surgery: A Prospective Observational Study
- Authors
- Zhang, Y. Hu, J. Zuo, W. He, P. Xue, Q. Feng, X. Zhang, Y. Maze, M.
- Year
- 2023
- Journal
- Anesth Analg
- Abstract
BACKGROUND: Surgery is accompanied by a systemic inflammatory response that may presage delirium in susceptible individuals. Little is known about the trajectory of plasma proinflammatory cytokines and their potential associations with postoperative delirium (POD). The current study longitudinally assessed both pro and anti-inflammatory plasma cytokine response and development of POD in older surgical patients to investigate associations with individual and/or clusters of cytokines that may indicate pathogenic mechanisms. METHODS: A prospective longitudinal study sought to enroll patients >60 years old who were scheduled for major lower limb surgery under general anesthesia. Blood was obtained preoperatively and postoperatively from day 1 through postoperative day 4 for measurement of plasma interleukin-1β (IL-1β), IL-2, IL-4, IL-6, soluble IL-6 receptor (sIL-6R), IL-10, and tumor necrosis factor-α (TNF-α). Participants were assessed for POD twice daily for 4 days using the confusion assessment method. Trajectory of postoperative changes in plasma cytokines was determined by a group-based trajectory modeling analysis that was informed by distinct cytokines identified by time-dependent Cox regression model. RESULTS: One hundred eighty-eight patients were assessed for eligibility of whom 129 underwent major surgery and 126 had complete datasets for final analysis. POD was diagnosed in 31 of 126 patients (24.6%). Time-dependent Cox regression model identified that higher IL-6 and sIL-6R levels were associated with higher risk of developing POD. A two-cluster model (stable lower and fluctuating higher levels) was considered to be the most statistically appropriate model for IL-6 and sIL-6R trajectory. More participants with fluctuating higher IL-6 were delirious (73.3% vs 18.0%, P = .001) as were those with fluctuating higher sIL-6R (81.3% vs 16.4%, P = .001). CONCLUSIONS: As higher IL-6 and sIL-6R levels were significantly associated with higher risk of POD and the combination is required for IL-6 trans-signaling, it is possible that activation of this pathway may be associated with POD. Furthermore, it will be important to determine whether high levels of the combination of IL-6 and sIL-6R can be an early biomarker for the subsequent development of POD.
- PMID
- Keywords
Humans
Aged
Middle Aged
*Cytokines
Interleukin-6
*Emergence Delirium
Prospective Studies
Longitudinal Studies
Lower Extremity
- Page(s)
- Volume
- Issue
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| Age- and gender-related peculiarities of patients with delirium in the cardiac intensive care unit. | Serpytis, P. Navickas, P. Navickas, A. Serpytis, R. Navickas, G. Glaveckaite, S. | Kardiol Pol | 2017 |
age |
| Delirium Frequency and Risk Factors Among Patients With Cancer in Palliative Care Unit. | Şenel G, Uysal N, Oguz G, Kaya M, Kadioullari N, Koçak N, Karaca S | The American journal of hospice & palliative care | 2017 |
adult |
| Plasma melatonin levels in hip fracture patients with and without delirium: A confirmation study. | Scholtens, R. M. van Munster, B. C. van Faassen, M. van Kempen, M. F. Kema, I. P. de Rooij, S. E. | Mech Ageing Dev | 2017 |
Aged |
| Association between delirium and cognitive change after cardiac surgery. | Sauer, A. C. Veldhuijzen, D. S. Ottens, T. H. Slooter, A. J. C. Kalkman, C. J. van Dijk, D. | Br J Anaesth | 2017 |
cardiac surgical procedures |
| Effectiveness and Safety of an Extended ICU Visitation Model for Delirium Prevention: A Before and After Study. | Rosa, R. G. Tonietto, T. F. da Silva, D. B. Gutierres, F. A. Ascoli, A. M. Madeira, L. C. Rutzen, W. Falavigna, M. Robinson, C. C. Salluh, J. I. Cavalcanti, A. B. Azevedo, L. C. Cremonese, R. V. Haack, T. R. Eugenio, C. S. Dornelles, A. Bessel, M. Teles, | Crit Care Med | 2017 |
Aged |
| Association of postoperative delirium with markers of neurodegeneration and brain amyloidosis: a pilot study. | Rolandi, E. Cavedo, E. Pievani, M. Galluzzi, S. Ribaldi, F. Buckley, C. Cunningham, C. Guerra, U. P. Musarra, M. Morzenti, S. Magnaldi, S. Patassini, M. Terragnoli, F. Matascioli, L. Franzoni, S. Annoni, G. Carnevali, L. Bellelli, G. Frisoni, G. B. | Neurobiol Aging | 2017 |
Alzheimer’s disease |
| Misidentification of mental health symptoms in presence of organic diseases and delirium during psychiatric liaison consulting. | Otani, V. H. O. Otani, Tzds Freirias, A. Calfat, E. L. B. Aoki, P. S. Cordeiro, Q. Junior Kanaan, R. A. A. Cross, S. Liersch-Sumskis, S. Uchida, R. R. | Int J Psychiatry Clin Pract | 2017 |
Diagnostic errors |
| A randomised trial of peri-operative positive airway pressure for postoperative delirium in patients at risk for obstructive sleep apnoea after regional anaesthesia with sedation or general anaesthesia for joint arthroplasty. | Nadler, J. W. Evans, J. L. Fang, E. Preud'Homme, X. A. Daughtry, R. L. Chapman, J. B. Bolognesi, M. P. Attarian, D. E. Wellman, S. S. Krystal, A. D. | Anaesthesia | 2017 |
clinical trial |
| Using anchors from free text in electronic health records to diagnose postoperative delirium. | Mikalsen, K. Ø Soguero-Ruiz, C. Jensen, K. Hindberg, K. Gran, M. Revhaug, A. Lindsetmo, R. O. Skrøvseth, S. O. Godtliebsen, F. Jenssen, R. | Computer Methods and Programs in Biomedicine | 2017 |
haloperidol |
| Postinjection delirium/sedation syndrome in patients with schizophrenia receiving olanzapine long-acting injection: results from a large observational study. | Meyers, K. J. Upadhyaya, H. P. Landry, J. L. Chhabra-Khanna, R. Falk, D. M. Seetharama Rao, B. Jones, M. E. | BJ Psych Open | 2017 | |
| Risk Factors for Delirium in Older Medical Inpatients in Tanzania. | Lewis, E. G. Banks, J. Paddick, S. M. Duinmaijer, A. Tucker, L. Kisoli, A. Cletus, J. Lissu, C. Kilonzo, K. Cosker, G. Mukaetova-Ladinska, E. B. Dotchin, C. Gray, W. Walker, R. Urasa, S. | Dement Geriatr Cogn Disord | 2017 |
Delirium |
| The experience of intensive care nurses caring for patients with delirium: A phenomenological study. | LeBlanc, A. Bourbonnais, F. F. Harrison, D. Tousignant, K. | Intensive Crit Care Nurs | 2017 |
Critical care |
| Pre-stroke apathy symptoms are associated with an increased risk of delirium in stroke patients | Klimiec, E. Kowalska, K. Pasinska, P. Klimkowicz-Mrowiec, A. Szyper, A. Pera, J. Slowik, A. Dziedzic, T. | Sci Rep | 2017 | |
| Current practice and opinions of hospital pharmacists regarding their role in the screening, prevention and treatment of delirium. | Kassie, G. M. Kalisch Ellett, L. M. Nguyen, T. A. Roughead, E. E. | Int J Clin Pharm | 2017 |
Australia |
| An educational programme to improve acute care nurses' knowledge, attitudes and family caregiver involvement in care of people with cognitive impairment. | Kang, Y. Moyle, W. Cooke, M. O'Dwyer, S. T. | Scand J Caring Sci | 2017 |
carers |
| Prognostic value of acute delirium recovery in older adults. | Jorge-Ripper C, Alemán MR, Ros R, Aguilera S, González-Reimers E, Espelosín E, Santolaria F | Geriatrics & gerontology international | 2016 |
Sepsis — Prognosis |
| Perceptions, attitudes, and current practices regards delirium in China: A survey of 917 critical care nurses and physicians in China. | Xing, J. Sun, Y. Jie, Y. Yuan, Z. Liu, W. | Medicine | 2017 | |
| Postoperative Delirium in Patients after Pancreaticoduodenectomy. | Ito Y, Abe Y, Handa K, Shibutani S, Egawa T, Nagashima A, Kitago M, Itano O, Kitagawa Y | Digestive surgery | 2017 |
Age Factors, Aged, Aged, 80 and over, Area Under Curve, Biliary Tract Neoplasms, surgery, Comorbidity, Delirium, etiology, Female, Humans, Male, Middle Aged, Pancreatic Neoplasms, surgery, Pancreaticoduodenectomy, adverse effects, Postoperative Complications, etiology, ROC Curve, Retrospective Studies, Risk Factors |
| Effect of lorazepam with haloperidol vs haloperidol alone on agitated delirium in patients with advanced cancer receiving palliative care: A randomized clinical trial | Hui, D. Frisbee-Hume, S. Wilson, A. Dibaj, S. S. Nguyen, T. De La Cruz, M. Walker, P. Zhukovsky, D. S. Delgado-Guay, M. Vidal, M. Epner, D. Reddy, A. Tanco, K. Williams, J. Hall, S. Liu, D. Hess, K. Amin, S. Breitbart, W. Bruera, E. | JAMA | 2017 |
NCT01949662 |
| Surgery and Anesthesia Exposure Is Not a Risk Factor for Cognitive Impairment After Major Noncardiac Surgery and Critical Illness. | Hughes CG, Patel MB, Jackson JC, Girard TD, Geevarghese SK, Norman BC, Thompson JL, Chandrasekhar R, Brummel NE, May AK, Elstad MR, Wasserstein ML, Goodman RB, Moons KG, Dittus RS, Ely EW, Pandharipande PP, | Annals of surgery | 2016 |
Aged |
| Incidence of postoperative delirium in patients undergoing total knee arthroplasty-an Asian perspective. | Huang, J. Bin Abd Razak, H. R. Yeo, S. J. | Ann Transl Med | 2017 |
Asian |
| Reevaluation of a clinical resource for assessment of delirium, dementia, and depression. | Horvath, K. J. Burns, T. Fernandez, C. Huh, J. W. T. Moorer, J. Thielke, S. Trittschuh, E. Cooley, S. | Gerontol Geriatr Educ | 2017 |
Delirium |
| New institutionalisation following acute hospital admission: A retrospective cohort study | Harrison, J. K. Garrido, A. G. Rhynas, S. J. Logan, G. Maclullich, A. M. J. Macarthur, J. Shenkin, S. | Age & Ageing | 2017 |
neuroleptic agent |
| Excited Delirium: A Systematic Review. | Gonin, P. Beysard, N. Yersin, B. Carron, P. N. | Acad Emerg Med | 2017 |
Agitation |
| Effectiveness of a Multifaceted Delirium Screening, Prevention, and Treatment Initiative on the Rate of Delirium Falls in the Acute Care Setting. | Ferguson, A. Uldall, K. Dunn, J. Blackmore, C. C. Williams, B. | J Nurs Care Qual | 2017 | |
| Depression as an independent predictor of postoperative delirium in spine deformity patients undergoing elective spine surgery. | Elsamadicy, A. A. Adogwa, O. Lydon, E. Sergesketter, A. Kaakati, R. Mehta, A. I. Vasquez, R. A. Cheng, J. Bagley, C. A. Karikari, I. O. | J Neurosurg Spine | 2017 |
Academic Medical Centers |
| Functional trajectories of older patients admitted to an Acute Care Unit for Elders. | D'Onofrio, A. Bula, C. Rubli, E. Butrogno, F. Morin, D. | Int J Older People Nurs | 2017 |
delirium |
| Managing delirium behaviors with one-to-one sitters. | Colella, J. Aroh, D. Douglas, C. VanBuitenen, N. Galesi, J. Castro, A. Tank, L. Parulekar, M. Menacker, M. | Nurs Manage | 2017 | |
| Clinical Assessment and Management of Delirium in the Palliative Care Setting | Bush, Shirley Lawlor, Peter Tierney, Sallyanne | Drugs | 2017 |
Delirium — Therapy |
| Perceptions of workload burden and adherence to ABCDE bundle among intensive care providers. | Boehm, Leanne M. | American Journal of Critical Care | 2017 |
Critical Care Nursing |
| Optimizing Surgical Quality Datasets to Care for Older Adults: Lessons from the American College of Surgeons NSQIP Geriatric Surgery Pilot. | Berian, J. R. Zhou, L. Hornor, M. A. Russell, M. M. Cohen, M. E. Finlayson, E. Ko, C. Y. Robinson, T. N. Rosenthal, R. A. | J Am Coll Surg | 2017 | |
| Post-ICU psychological morbidity in very long ICU stay patients with ARDS and delirium. | Bashar, F. R. Vahedian-Azimi, A. Hajiesmaeili, M. Salesi, M. Farzanegan, B. Shojaei, S. Goharani, R. Madani, S. J. Moghaddam, K. G. Hatamian, S. Moghaddam, H. J. Mosavinasab, S. M. M. Elamin, E. M. Miller, A. C. | J Crit Care | 2017 |
Acute respiratory distress syndrome |
| The prevalence of undiagnosed pre-surgical cognitive impairment and its post-surgical clinical impact in elderly patients undergoing surgery for adult spinal deformity. | Adogwa, O. Elsamadicy, A. A. Lydon, E. Vuong, V. D. Cheng, J. Karikari, I. O. Bagley, C. A. | J Spine Surg | 2017 |
Surgery |
| A comparison of outcomes according to different diagnostic systems for delirium (DSM-5, DSM-IV, CAM, and DRS-R98). | Adamis, D. Meagher, D. Rooney, S. Mulligan, O. McCarthy, G. | Int Psychogeriatr | 2017 |
Dsm |
| Antipsychotic prescription to identify delirium: results from two cohorts. | Zimmerman, K. M. Paquin, A. M. Rudolph, J. L. | Clin Pharmacol | 2017 |
delirium antipsychotic aged |
| Preoperative severe hypoalbuminemia is associated with an increased risk of postoperative delirium in elderly patients: Results of a secondary analysis. | Zhang, D. F. Su, X. Meng, Z. T. Cui, F. Li, H. L. Wang, D. X. Li, X. Y. | J Crit Care | 2017 |
Delirium |
| Rivastigmine patch reduces the incidence of postoperative delirium in older patients with cognitive impairment | Young, Y. C. Shin, H. W. Choi, B. S. Kim, S. Lee, J. Y. Ha, Y. C. | Int J Geriatr Psychiatry | 2017 |
acetylcholinesterase inhibitors |
| Effects of nimodipine on postoperative delirium in elderly under general anesthesia: A prospective, randomized, controlled clinical trial | Ya-Nan, Li Qi, Zhang Chun-Ping, Yin Yang-Yang, Guo Shu-Ping, Huo Liang, Wang Qiu-Jun, Wang Li, Ya-Nan Zhang, Qi Yin, Chun-Ping Guo, Yang-Yang Huo, Shu-Ping Wang, Liang Wang, Qiu-Jun | Medicine | 2017 | |
| Association of intraoperative changes in brain-derived neurotrophic factor and postoperative delirium in older adults. | Wyrobek, J. LaFlam, A. Max, L. Tian, J. Neufeld, K. J. Kebaish, K. M. Walston, J. D. Hogue, C. W. Riley, L. H. Everett, A. D. Brown, C. H. th | Br J Anaesth | 2017 |
Bdnf |
| Preoperative geriatric assessment reduced hospital stay and complications in patients ≥65 y having vascular surgery. | Weed, H. G. | Annals of Internal Medicine | 2017 |
ISRCTN23142588 |
| The Risk Factors of Postoperative Delirium after Total Knee Arthroplasty. | Wang, L. Seok, S. Kim, S. Kim, K. Lee, S. Lee, K. | J Knee Surg | 2017 | |
| Risk factors for the incidence of delirium in cerebrovascular patients in a Neurosurgery Intensive Care Unit: A prospective study. | Wang, J. Ji, Y. Wang, N. Chen, W. Bao, Y. Qin, Q. Xiao, Q. Li, S. | J Clin Nurs | 2017 |
delirium (mental health nursing) |
| Clock-Drawing Test as a Bedside Assessment of Post-operative Delirium Risk in Elderly Patients with Accidental Hip Fracture. | Vasilian, C. C. Tamasan, S. C. Lungeanu, D. Poenaru, D. V. | World J Surg | 2017 | |
| A prospective observational study to investigate utility of the Delirium Observational Screening Scale (DOSS) to detect delirium in care home residents. | Teale, E. A. Munyombwe, T. Schuurmans, M. Siddiqi, N. Young, J. | Age & Ageing | 2017 |
Delirium Observation Screening Scale |
| Randomized phase II study of TJ-54 (Yokukansan) for postoperative delirium in gastrointestinal and lung malignancy patients. | Sugano, N. Aoyama, T. Sato, T. Kamiya, M. Amano, S. Yamamoto, N. Nagashima, T. Ishikawa, Y. Masudo, K. Taguri, M. Yamanaka, T. Yamamoto, Y. Matsukawa, H. Shiraisi, R. Oshima, T. Yukawa, N. Rino, Y. Masuda, M. | Mol Clin Oncol | 2017 |
Yokukansan |
| Postoperative delirium in elderly patients is associated with subsequent cognitive impairment. | Sprung, J. Roberts, R. O. Weingarten, T. N. Nunes Cavalcante, A. Knopman, D. S. Petersen, R. C. Hanson, A. C. Schroeder, D. R. Warner, D. O. | Br J Anaesth | 2017 |
aged, humans |
| Delirium Following Transcatheter Aortic Valve Replacement: National Inpatient Sample Analysis. | Soundhar, A. Udesh, R. Mehta, A. Schindler, J. Jeevanantham, V. Gleason, T. Thirumala, P. D. | Journal of Cardiothoracic and Vascular Anesthesia | 2017 |
carotid artery obstruction |
| The Effects of Delirium Prevention Guidelines on Elderly Stroke Patients | Song, J. Lee, M. Jung, D. | Clin Nurs Res | 2017 |
delirium |
| Postoperative Delirium in Elderly Patients Undergoing Major Spinal Surgery: Role of Cerebral Oximetry. | Soh S, Shim JK, Song JW, Kim KN, Noh HY, Kwak YL | Journal of neurosurgical anesthesiology | 2016 | |
| Age and gender-related peculiarities of patients with delirium in the cardiac intensive care unit. | Serpytis, P. Navickas, P. Navickas, A. Serpytis, R. Navickas, G. Glaveckaite, S. | Kardiol Pol | 2017 |
Iccu |
| Outcomes of subsyndromal delirium in ICU: a systematic review and meta-analysis. | Serafim, R. B. Soares, M. Bozza, F. A. Lapa, E. Silva J. R. Dal-Pizzol, F. Paulino, M. C. Povoa, P. Salluh, J. I. F. | Crit Care | 2017 |
Critically ill |
| Haloperidol versus placebo for delirium prevention in acutely hospitalised older at risk patients: a multi-centre double-blind randomised controlled clinical trial. | Schrijver, E. J. M. de Vries, O. J. van de Ven, P. M. Bet, P. M. Kamper, A. M. Diepeveen, S. H. A. van Marum, R. J. van Strien, A. M. Anten, S. Lagaay, A. M. Boelaarts, L. Bloemers, F. W. Kramer, M. H. H. Nanayakkara, P. W. B. | Age & Ageing | 2017 |
aged 80 and over |
| The impact of delirium on outcomes in acute, non-intubated cardiac patients. | Sato K, Kubota K, Oda H, Taniguchi T | European heart journal. Acute cardiovascular care | 2015 |
Aging |
| Epidemiology and outcomes of people with dementia, delirium, and unspecified cognitive impairment in the general hospital: prospective cohort study of 10,014 admissions. | Reynish, Emma L. Hapca, Simona M. De Souza, Nicosha Cvoro, Vera Donnan, Peter T. Guthrie, Bruce | BMC Medicine | 2017 | |
| Alzheimer's-related cortical atrophy is associated with postoperative delirium severity in persons without dementia. | Racine, A. M. Fong, T. G. Travison, T. G. Jones, R. N. Gou, Y. Vasunilashorn, S. M. Marcantonio, E. R. Alsop, D. C. Inouye, S. K. Dickerson, B. C. | Neurobiol Aging | 2017 |
Alzheimer’s disease |
| Delayed Recall and Working Memory MMSE Domains Predict Delirium following Cardiac Surgery. | Price, C. C. Garvan, C. Hizel, L. Lopez, M. G. Billings, F. T. | J Alzheimers Dis | 2017 |
Alzheimer’s disease |
| The detection, diagnosis, and impact of cognitive impairment among inpatients aged 65 years and over in an Irish general hospital - a prospective observational study. | Power, C. Duffy, R. Bates, H. Healy, M. Gleeson, P. Lawlor, B. A. Greene, E. | Int Psychogeriatr | 2017 |
cognitive impairment |
| Incidence and predictors of postoperative delirium after cytoreduction surgery-hyperthermic intraperitoneal chemotherapy. | Plas, M. Hemmer, P. H. J. Been, L. B. van Ginkel, R. J. de Bock, G. H. van Leeuwen, B. L. | J Surg Oncol | 2017 |
C-reactive protein |
| Role of Ramelteon in Reduction of As-Needed Antipsychotics in Elderly Patients with Delirium in a General Hospital Setting. | Pinkhasov, A. James, S. A. Fazzari, M. Singh, D. Lam, S. | Clin Drug Investig | 2017 | |
| Delirium after fast-track hip and knee arthroplasty - a cohort study of 6331 elderly patients. | Petersen, P. B. Jorgensen, C. C. Kehlet, H. | Acta Anaesthesiol Scand | 2017 | |
| Delirium Risk of Dexmedetomidine and Midazolam in Patients Treated with Postoperative Mechanical Ventilation: a Meta-analysis. | Peng, W. Shimin, S. Hongli, W. Yanli, Z. Ying, Z. | Open Med | 2017 |
Delirium |
| Humanizing the treatment of hyperactive delirium in the last days of life. | Pandharipande, P. P. Ely, E. W. | JAMA | 2017 |
haloperidol |
| Evaluation of early administration of simvastatin in the prevention and treatment of delirium in critically ill patients undergoing mechanical ventilation (MoDUS): a randomised, double-blind, placebo-controlled trial. | Page, V. J. Casarin, A. Ely, E. W. Zhao, X. B. McDowell, C. Murphy, L. McAuley, D. F. | Lancet Respir Med | 2017 | |
| The effect of nonpharmacological training on delirium identification and intervention strategies of intensive care nurses. | Ozturk Birge, A. Tel Aydin, H. | Intensive Crit Care Nurs | 2017 |
Adult |
| Validation of the 6-Item Cognitive Impairment Test and the 4AT test for combined delirium and dementia screening in older Emergency Department attendees. | O'Sullivan, D. Brady, N. Manning, E. O'Shea, E. O'Grady, S. O. ' Regan N Timmons, S. | Age & Ageing | 2017 |
delirium |
| Risk factors for delirium after cardiac surgery: a historical cohort study outlining the influence of cardiopulmonary bypass. | O'Neal, J. B. Billings, F. T. th Liu, X. Shotwell, M. S. Liang, Y. Shah, A. S. Ehrenfeld, J. M. Wanderer, J. P. Shaw, A. D. | Can J Anaesth | 2017 | |
| A systematic review and meta-analysis of factors for delirium in vascular surgical patients. | Oldroyd, C. Scholz, A. F. M. Hinchliffe, R. J. McCarthy, K. Hewitt, J. Quinn, T. J. | J Vasc Surg | 2017 |
Delirium/diagnosis/*etiology/psychology/therapy |
| Detection and Management of Preexisting Cognitive Impairment in the Critical Care Unit. | Oldham, M. A. Piddoubny, W. Peterson, R. Lee, H. B. | Crit Care Clin | 2017 |
Behavioral and psychological symptoms in dementia |
| Delirium in older persons: Advances in diagnosis and treatment. | Oh, E. S. Fong, T. G. Hshieh, T. T. Inouye, S. K. | JAMA | 2017 |
biological marker |
| Prevalence for delirium in stroke patients: A prospective controlled study. | Nydahl, P. Bartoszek, G. Binder, A. Paschen, L. Margraf, N. G. Witt, K. Ewers, A. | Brain Behav | 2017 |
Confusion Assessment Method |
| Perioperative hemodynamics and risk for delirium and new onset dementia in hip fracture patients; A prospective follow-up study. | Neerland, B. E. Krogseth, M. Juliebo, V. Hylen Ranhoff, A. Engedal, K. Frihagen, F. Raeder, J. Bruun Wyller, T. Watne, L. O. | PloS One | 2017 | |
| Effects of closed-loop intravenous anesthesia guided by the Bispectral index in adult patients on emergence delirium. A randomized controlled study. | Cotoia, A. Mirabella, L. Beck, R. Matrella, P. Assenzo, V. Chazot, T. Cinnella, G. Liu, N. Dambrosio, M. | Minerva Anestesiol | 2017 | |
| Early impairment of intracranial conduction time predicts mortality in deeply sedated critically ill patients: a prospective observational pilot study. | Azabou, E. Rohaut, B. Heming, N. Magalhaes, E. Morizot-Koutlidis, R. Kandelman, S. Allary, J. Moneger, G. Polito, A. Maxime, V. Annane, D. Lofaso, F. Chretien, F. Mantz, J. Porcher, R. Sharshar, T. | Ann Intensive Care | 2017 |
Altered mental status |
| Prevalence of Delirium in a Population of Elderly Outpatients with Dementia: A Retrospective Study. | Addesi, D. Maio, R. Smirne, N. Laganà, V. Altomari, N. Puccio, G. Colao, R. Cupidi, C. Perticone, F. Bruni, A. C. | Journal of Alzheimer's Disease | 2017 |
antidepressant agent |
| Validation and Psychometric Properties of the German Version of the Delirium Motor Subtype Scale (DMSS). | Garcia Nunez, D. Boettger, S. Meyer, R. Richter, A. Schubert, M. Meagher, D. Jenewein, J. | Assessment | 2017 |
German version |
| Association of Helicobacter pylori with the Risk of Hepatic Encephalopathy. | Wijarnpreecha, K. Chesdachai, S. Thongprayoon, C. Jaruvongvanich, V. Ungprasert, P. Cheungpasitporn, W. | Dig Dis Sci | 2017 |
Helicobacter Infections/*complications |
| Determination of the feasibility of a multicomponent intervention program to prevent delirium in the Intensive Care Unit: A modified RAND Delphi study. | Wassenaar, A. van den Boogaard, M. Underpin-Icu Study, Group Schoonhoven, L. Pickkers, P. | Aust Crit Care | 2017 |
Delirium |
| Incidence, correlates and outcomes associated with falls in the intensive care unit: a retrospective cohort study. | Trumble, D. Meier, M. A. Doody, M. Wang, X. Bagshaw, S. M. | Crit Care Resusc | 2017 | |
| Impact of the Orthopaedic Nurse Practitioner role on acute hospital length of stay and cost-savings for patients with hip fracture: A retrospective cohort study. | Coventry, L. L. Pickles, S. Sin, M. Towell, A. Giles, M. Murray, K. Twigg, D. E. | J Adv Nurs | 2017 |
cost-savings |
| Prevalence and risk factors for delirium diagnosis in patients followed in general practices in Germany. | Bohlken, Jens Kostev, Karel | International Psychogeriatrics | 2017 |
delirium |
| Clinical benefits of single-incision laparoscopic surgery for postoperative delirium in elderly colon cancer patients. | Nishizawa, Y. Hata, T. Takemasa, I. Yamasaki, M. Akasaka, H. Sugimoto, K. Tamai, K. Takahashi, H. Haraguchi, N. Nishimura, J. Matsuda, C. Mizushima, T. Ikenaga, M. Yamamoto, H. Murata, K. Rakugi, H. Doki, Y. Mori, M. | Surg Endosc | 2017 |
aged |
| Evaluation of Cognitive Function Following Transcatheter Aortic Valve Replacement. | Abawi, M. de Vries, R. Stella, P. R. Agostoni, P. Boelens, D. H. M. van Jaarsveld, R. C. van Dongen, C. S. Doevendans, P. A. F. M. Emmelot-Vonk, M. H. | Heart Lung and Circulation | 2017 |
adult |
| Preoperative Risk Factors for Subsyndromal Delirium in Older Adults Who Undergo Joint Replacement Surgery. | Denny, D. L. Lindseth, G. | Orthop Nurs | 2017 | |
| Validating the 4A's test in screening for delirium in a culturally diverse geriatric inpatient population. | De, J. Wand, A. P. F. Smerdely, P. I. Hunt, G. E. | Int J Geriatr Psychiatry | 2017 |
delirium screening |
| Delirium, frailty and mortality: interactions in a prospective study of hospitalized older people. | Dani, M. Owen, L. H. Jackson, T. A. Rockwood, K. Sampson, E. L. Davis, D. | J Gerontol A Biol Sci Med Sci | 2017 |
Outcomes |
| Impact of inhalational versus intravenous anaesthesia on early delirium and long-term survival in elderly patients after cancer surgery: study protocol of a multicentre, open-label, and randomised controlled trial. | Zhang, Y. Li, H. J. Wang, D. X. Jia, H. Q. Sun, X. D. Pan, L. H. Ye, Q. S. Ouyang, W. Jia, Z. Zhang, F. X. Guo, Y. Q. Ai, Y. Q. Zhao, B. J. Yang, X. D. Zhang, Q. G. Yin, N. Tan, H. Y. Liu, Z. H. Yu, J. B. Ma, D. | BMJ Open | 2017 |
anaesthesia in oncology |
| Hypertonic saline for prevention of delirium in geriatric patients who underwent hip surgery. | Xin, X. Xin, F. Chen, X. Zhang, Q. Li, Y. Huo, S. Chang, C. Wang, Q. | J Neuroinflammation | 2017 |
Cytokines |
| Delirium and Catatonia in Critically Ill Patients: The Delirium and Catatonia Prospective Cohort Investigation. | Wilson, J. E. Carlson, R. Duggan, M. C. Pandharipande, P. Girard, T. D. Wang, L. Thompson, J. L. Chandrasekhar, R. Francis, A. Nicolson, S. E. Dittus, R. S. Heckers, S. Ely, E. W. | Crit Care Med | 2017 |
Aged |
| Ketamine for the acute management of excited delirium and agitation in the prehospital setting. | Weant, K. A. Linder, L. M. Ross, C. A. | Pharmacotherapy | 2017 |
Agitation |
| Improved detection of delirium, implementation and validation of the CAM-ICU in elderly Emergency Department patients. | Van de Meeberg EK, Festen S, Kwant M, Georg RR, Izaks GJ, Ter Maaten JC | European journal of emergency medicine : official journal of the European Society for Emergency Medicine | 2016 | |
| Delirium symptoms are associated with decline in cognitive function between ages 53 and 69 years: Findings from a British birth cohort study. | Tsui, A. Kuh, D. Richards, M. Davis, D. | Alzheimers Dement | 2017 |
Cognitive decline |
| Delirium is associated with increased mortality in the geriatric population. | Tosun Tasar, P. Sahin, S. Akcam, N. O. Dinckal, C. Ulusoy, M. G. Sarikaya, O. F. Duman, S. Akcicek, F. Noyan, A. | Int J Psychiatry Clin Pract | 2017 |
Delirium |
| Disturbances in Oxygen Balance During Cardiopulmonary Bypass: A Risk Factor for Postoperative Delirium. | Smulter, N. Lingehall, H. C. Gustafson, Y. Olofsson, B. Engström, K. G. Appelblad, M. Svenmarker, S. | J Cardiothorac Vasc Anesth | 2017 |
aged |
| Perceptions of Family Members, Nurses, and Physicians on Involving Patients' Families in Delirium Prevention. | Smithburger, P. L. Korenoski, A. S. Kane-Gill, S. L. Alexander, S. A. | Crit Care Nurse | 2017 | |
| Perceptions of Families of Intensive Care Unit Patients Regarding Involvement in Delirium-Prevention Activities: A Qualitative Study. | Smithburger, P. L. Korenoski, A. S. Alexander, S. A. Kane-Gill, S. L. | Crit Care Nurse | 2017 | |
| A Predictive Model of the Prevalence of Delirium in Elderly Subjects Admitted to Nursing Homes. | Perez-Ros, P. Martinez-Arnau, F. M. Baixauli-Alacreu, S. Garcia-Gollarte, J. F. Tarazona-Santabalbina, F. | Endocr Metab Immune Disord Drug Targets | 2017 |
Delirium |
| Incidence and Risk Factors for Postoperative Delirium in Patients After Hepatectomy. | Park SA, Tomimaru Y, Shibata A, Miyagawa S, Noguchi K, Dono K | World journal of surgery | 2017 | |
| Five short screening tests in the detection of prevalent delirium: diagnostic accuracy and performance in different neurocognitive subgroups. | O'Regan, N. A. Maughan, K. Liddy, N. Fitzgerald, J. Adamis, D. Molloy, D. W. Meagher, D. Timmons, S. | Int J Geriatr Psychiatry | 2017 |
cognition |
| Midterm outcomes after postoperative delirium on cognition and mood in patients after cardiac surgery. | Nguyen, Q. Uminski, K. Hiebert, B. M. Tangri, N. Arora, R. C. | Journal of Thoracic and Cardiovascular Surgery | 2017 |
adult |
| The delirium drug scale is associated to delirium incidence in the emergency department. | Nguyen, Patrick Viet-Quoc Pelletier, Lucie Payot, Isabelle Latour, Judith | International Psychogeriatrics | 2017 |
delirium |