What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Postoperative delirium and changes in the blood-brain barrier, neuroinflammation, and cerebrospinal fluid lactate: a prospective cohort study
- Authors
- Taylor, J. Parker, M. Casey, C. P. Tanabe, S. Kunkel, D. Rivera, C. Zetterberg, H. Blennow, K. Pearce, R. A. Lennertz, R. C. Sanders, R. D.
- Year
- 2022
- Journal
- Br J Anaesth
- Abstract
BACKGROUND: Case-control studies have associated delirium with blood-brain barrier (BBB) permeability. However, this approach cannot determine whether delirium is attributable to high pre-existing permeability or to perioperative changes. We tested whether perioperative changes in cerebrospinal fluid/plasma albumin ratio (CPAR) and plasma S100B were associated with delirium severity. METHODS: Participants were recruited to two prospective cohort studies of non-intracranial surgery (NCT01980511, NCT03124303, and NCT02926417). Delirium severity was assessed using the Delirium Rating Scale-98. Delirium incidence was diagnosed with the 3D-Confusion Assessment Method (3D-CAM) or CAM-ICU (CAM for the ICU). CSF samples from 25 patients and plasma from 78 patients were analysed for albumin and S100B. We tested associations between change in CPAR (n=11) and S100B (n=61) and delirium, blood loss, CSF interleukin-6 (IL-6), and CSF lactate. RESULTS: The perioperative increase in CPAR and S100B correlated with delirium severity (CPAR ρ=0.78, P=0.01; S100B ρ=0.41, P<0.001), delirium incidence (CPAR P=0.012; S100B P<0.001) and CSF IL-6 (CPAR ρ=0.66 P=0.04; S100B ρ=0.75, P=0.025). Linear mixed-effect analysis also showed that decreased levels of S100B predicted recovery from delirium symptoms (P=0.001). Linear regression demonstrated that change in plasma S100B was independently associated with surgical risk, cardiovascular surgery, blood loss, and hypotension. Blood loss also correlated with CPAR (ρ=0.64, P=0.04), S100B (ρ=0.70, P<0.001), CSF lactate (R=0.81, P=0.01), and peak delirium severity (ρ=0.36, P=0.01). CONCLUSION: Postoperative delirium is associated with a breakdown in the BBB. This increased permeability is dynamic and associated with a neuroinflammatory and lactate response. Strategies to mitigate blood loss may protect the BBB.
- PMID
- Keywords
Biomarkers
*Blood-Brain Barrier
*Delirium/diagnosis
Humans
Interleukin-6
Lactic Acid
Neuroinflammatory Diseases
Prospective Studies
S100 Calcium Binding Protein beta Subunit/cerebrospinal fluid
*delirium
*dementia
*inflammation
*neuronal injury
*older adults
*surgery
- Page(s)
- Volume
- Issue
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| Postoperative Delirium and the Older Adult: Untangling the Confusion | Thedim, M. Vacas, S. | J Neurosurg Anesthesiol | 2024 |
aging, anesthesia, delirium, inflammation, sleep |
| Efficacy and safety of music therapy for the treatment of anxiety and delirium in ICU patients: a meta-analysis and systematic review of randomized controlled trials | Xiao, M. Gong, C. Mai, M. Huang, M. Xiong, A. Liu, H. Jiang, R. | Minerva Anestesiol | 2024 |
Music therapy; Intensive care units; Anxiety; Delirium; Meta-analysis |
| Aripiprazole for treating delirium: A systematic review-Is it a valid yet understudied treatment? | Maddalena, S. Magistri, C. Mellini, C. Sarli, G. | J Psychopharmacol | 2024 |
Haloperidol |
| Delirium screening in the emergency department: evaluation and intervention | Meged-Book, T. Frenkel, R. Nikonov, A. Zeldetz, V. Kosto, A. Schwarzfuchs, D. Freud, T. Press, Y. | Isr J Health Policy Res | 2024 |
Humans |
| A Toolkit for Delirium Identification and Promoting Partnerships Between Carers and Nurses: A Pilot Pre-Post Feasibility Study | Aggar, C. Craswell, A. Bail, K. Compton, R. M. Hughes, M. Sorwar, G. Baker, J. Greenhill, J. Shinners, L. Nichols, B. Langheim, R. Wallis, A. Bowen, K. Bridgett, H. | J Gen Intern Med | 2024 |
caregiving |
| The role of heart rate variability in predicting delirium: A systematic review and meta-analysis | Amit Patel, K. Sethi, A. Al Azazi, E. McClurg, C. Chowdhury, T. | J Clin Neurosci | 2024 |
Delirium |
| Efficacy of melatonin in decreasing the incidence of delirium in critically ill adults: a randomized controlled trial | Bandyopadhyay, A. Yaddanapudi, L. N. Saini, V. Sahni, N. Grover, S. Puri, S. Ashok, V. | Crit Care Sci | 2024 |
Humans |
| Assessment and report of individual symptoms in studies of delirium in postoperative populations: a systematic review | Bowman, E. M. L. Sweeney, A. M. McAuley, D. F. Cardwell, C. Kane, J. Badawi, N. Jahan, N. Iqbal, H. K. Mitchell, C. Ballantyne, J. A. Cunningham, E. L. | Age Ageing | 2024 |
Humans |
| Systemic inflammation and delirium during critical illness | Brummel, N. E. Hughes, C. G. McNeil, J. B. Pandharipande, P. P. Thompson, J. L. Orun, O. M. Raman, R. Ware, L. B. Bernard, G. R. Harrison, F. E. Ely, E. W. Girard, T. D. | Intensive Care Med | 2024 |
Coma |
| Hospitalized Patients With Delirium and 28-Day Unplanned Hospital Readmissions: A Longitudinal Retrospective Cohort Study | Butala, A. Gilbert, J. M. Griffiths, A. A. Lim, W. K. | J Am Med Dir Assoc | 2024 |
Delirium |
| Validity and reliability of the Turkish version of the Informant Assessment of Geriatric Delirium Scale | Celik, B. Bilik, O. Koçbilek, Z. D. Damar, H. T. Öz, D. Denizmen, Z. | Ideggyogy Sz | 2024 |
Aged |
| Can admission Braden skin score predict delirium in older adults in the intensive care unit? Results from a multicenter study | Cheng, H. Huang, X. Yuan, S. Song, S. Tang, Y. Ling, Y. Tan, S. Wang, Z. Zhou, F. Lyu, J. | J Clin Nurs | 2024 |
Humans |
| Malnutrition-Related Health Outcomes in Older Adults with Hip Fractures: A Systematic Review and Meta-Analysis | Chiavarini, M. Ricciotti, G. M. Genga, A. Faggi, M. I. Rinaldi, A. Toscano, O. D. D'Errico, M. M. Barbadoro, P. | Nutrients | 2024 |
Humans |
| Organizational Context and Facilitation Interactions on Delirium Risk in Long-Term Care: A Cross-Sectional Study | Choroschun, K. Estabrooks, C. A. Duan, Y. Chamberlain, S. Shrestha, S. Cummings, G. G. Iaconi, A. Norton, P. G. Song, Y. Hoben, M. | J Am Med Dir Assoc | 2024 |
Organizational context |
| Delirium and delirium severity screening in the intensive care-correspondence of screenings tools | Collet, M. O. Nielsen, A. H. Larsen, L. K. Laerkner, E. Jensen, J. F. Mortensen, C. B. Lehmkuhl, L. Thorn, L. Rossen, B. S. Nielsen, T. A. Laursen, E. Shiv, L. H. Villumsen, M. Rahr, M. N. Svenningsen, H. | Aust Crit Care | 2024 |
Adult |
| A joint frailty model for recurrent and competing terminal events: Application to delirium in the ICU | Etzkorn, L. H. Coënt, Q. L. van den Boogaard, M. Rondeau, V. Colantuoni, E. | Stat Med | 2024 |
competing events |
| Nomogram for predicting the risk of postoperative delirium in elderly patients undergoing orthopedic surgery | Fan, Y. Yang, T. Liu, Y. Gan, H. Li, X. Luo, Y. Yang, X. Pang, Q. | Perioper Med (Lond) | 2024 |
Elderly patients |
| The Association of Plasma Leptin, Soluble Leptin Receptor and Total and High-Molecular Weight Adiponectin With the Risk of Perioperative Neurocognitive Disorders | Feinkohl, I. Janke, J. Slooter, A. J. C. Winterer, G. Spies, C. Pischon, T. | Am J Geriatr Psychiatry | 2024 |
Adiponectin |
| A novel nomogram for the prediction of subsyndromal delirium in patients in intensive care units: A prospective, nested case-controlled study | Gao, Y. Gan, X. | Int J Nurs Stud | 2024 |
Delirium |
| Association Between Preoperative Sleep Disturbance and Postoperative Delirium in Elderly: A Retrospective Cohort Study | Guo, H. Li, L. H. Lv, X. H. Su, F. Z. Chen, J. Xiao, F. Shi, M. Xie, Y. B. | Nat Sci Sleep | 2024 |
anesthesia |
| Validation to Spanish of nursing assessment scale for early diagnosis of delirium - Nu-DESC | Henao Castaño Á, M. Lozano González, L. M. Gómez Tovar, L. O. | Invest Educ Enferm | 2023 |
Adult |
| Predictive modeling for postoperative delirium in elderly patients with abdominal malignancies using synthetic minority oversampling technique | Hu, W. J. Bai, G. Wang, Y. Hong, D. M. Jiang, J. H. Li, J. X. Hua, Y. Wang, X. Y. Chen, Y. | World J Gastrointest Oncol | 2024 |
Abdominal cancer |
| Reliability and Validity of the Spanish Adaptation of the Stanford Proxy Test for Delirium in Two Clinical Spanish-Speaking Communities | Infante, S. Behn, A. González, M. Pintor, L. Franco, E. Araya, P. Maldonado, J. R. | J Acad Consult Liaison Psychiatry | 2024 |
Humans |
| Detection of delirium in older patients-A point prevalence study in surgical and non-surgical hospital wards | Instenes, I. Eide, L. S. P. Andersen, H. Fålun, N. Pettersen, T. Ranhoff, A. H. Rudolph, J. L. Steihaug, O. M. Wentzel-Larsen, T. Norekvål, T. M. | Scand J Caring Sci | 2024 |
4at |
| The impact of delirium on clinical and functional outcomes in hospitalized patients with acute coronary syndrome | Ioanna, D. Evangelos, F. John, S. Aikaterini, T. Ioannis, V. Dimitrios, P. Maria, S. | Nurs Crit Care | 2024 |
acute coronary syndrome |
| Improving the Detection, Assessment, Management and Prevention of Delirium in Hospices (the DAMPen-D study): Feasibility study of a flexible and scalable implementation strategy to deliver guideline-adherent delirium care | Jackson, G. P. Jackson, C. E. Boland, J. W. Featherstone, I. Huang, C. Ogden, M. Sartain, K. Siddiqi, N. Twiddy, M. Pearson, M. Johnson, M. J. | Palliat Med | 2024 |
Humans |
| Diffuse optical tomography for mapping cerebral hemodynamics and functional connectivity in delirium | Jiang, S. Huang, J. Yang, H. Czuma, R. Farley, L. Cohen-Oram, A. Hartney, K. Chechotka, K. Kozel, F. A. Jiang, H. | Alzheimers Dement | 2024 |
acute brain failure |
| Cognitive Training for Reduction of Delirium in Patients Undergoing Cardiac Surgery: A Randomized Clinical Trial | Jiang, Y. Xie, Y. Fang, P. Shang, Z. Chen, L. Zhou, J. Yang, C. Zhu, W. Hao, X. Ding, J. Yin, P. Wang, Z. Cao, M. Zhang, Y. Tan, Q. Cheng, D. Kong, S. Lu, X. Liu, X. Sessler, D. I. | JAMA Netw Open | 2024 |
Humans |
| Physical activity may a probably protective factor for postoperative delirium: the PNDABLE study | Kong, J. Lin, X. Wang, B. Xu, S. Wang, Y. Hua, S. Gong, H. Dong, R. Lin, Y. Li, C. Bi, Y. | Front Aging Neurosci | 2024 |
Alzheimer-related biomarkers |
| Effects of Exercise Intervention for the Management of Delirium in Hospitalized Older Adults: A Randomized Clinical Trial | Lozano-Vicario, L. Zambom-Ferraresi, F. Zambom-Ferraresi, F. L. Sáez de Asteasu M Galbete-Jiménez, A. Muñoz-Vázquez Á, J. Cedeno-Veloz, B. A. De la Casa-Marín, A. Ollo-Martínez, I. Fernández-Irigoyen, J. Santamaría, E. San Miguel Elcano, R. Ortiz | J Am Med Dir Assoc | 2024 |
delirium |
| The association between the fibrinogen-to-albumin ratio and delirium after deep brain stimulation surgery in Parkinson's disease | Lu, W. Wang, H. Lin, S. Chang, X. Wang, J. Wu, X. Yu, X. | Front Med (Lausanne) | 2024 |
Parkinson’s disease |
| The Application Value of Esketamine and Dexmedetomidine in Preventing Postoperative Delirium and Hyperalgesia in Elderly Patients with Thoracic Anesthesia | Lu, Y. Yin, G. Jin, C. Gu, K. Bao, D. Xu, W. Yang, Z. | Altern Ther Health Med | 2024 |
Humans |
| A Molecular Framework for Delirium | Lyman, K. A. | Neurohospitalist | 2024 |
attention |
| Evaluation of Delirium Among Elders in the Emergency Department: A Cross-Sectional Study | Marcomini, I. Pisoni, L. Mellino, A. Labaran, R. Milani, L. | Dimens Crit Care Nurs | 2024 |
Humans |
| A Mediation Analysis Examining High Risk, Anticholinergic Medication Use, Delirium, and Dementia After Major Surgery | Mohanty, S. Lindroth, H. Timsina, L. Holler, E. Jenkins, P. Ortiz, D. Hur, J. Gillio, A. Zarzaur, B. Boustani, M. | J Surg Res | 2024 |
Anticholinergics |
| Comparing the delirium objective structured clinical examination (OSCE) education package to standard education for post-registration nurses: A randomised controlled trial | Montgomery, A. Smerdely, P. Hickman, L. Traynor, V. | Nurse Educ Today | 2024 |
Delirium |
| Postoperative cognitive dysfunction: Review of pathophysiology, diagnostics and preventive strategies | Nešković, N. Budrovac, D. Kristek, G. Kovačić, B. Škiljić, S. | J Perioper Pract | 2024 |
Neuroinflammation |
| Prognostic implications of delirium after Left Ventricular Assist Device (LVAD) implantation: A retrospective study | Noufi, P. Anderson, K. M. Crowell, N. White, Y. Molina, E. Rao, S. D. Groninger, H. | J Acad Consult Liaison Psychiatry | 2024 |
Delirium |
| Sex Differences in Delirium after Coronary Artery Bypass Graft Surgery and Perioperative Neuropsychiatric Conditions: A Secondary Analysis of a Cohort Study | Oldham, M. A. Kukla, B. Walsh, P. Lee, H. B. | J Geriatr Psychiatry Neurol | 2024 |
coronary artery bypass graft surgery outcomes |
| Incidence of confusional syndrome (delirium) in a Latin American university hospital | Oviedo Lugo, G. F. García Martínez, P. A. Duarte Osorio, A. Rincón, C. J. López, A. Chavarría, R. Pineda Betancur, C. García Gil, N. Duarte Ariza, M. N. Patiño Trejos, J. A. Insignares, J. S. Gómez-Restrepo, C. | Rev Colomb Psiquiatr (Engl Ed) | 2024 |
Cam |
| Postoperative cognitive disorders and delirium in gynecologic surgery: Which surgery and anesthetic techniques to use to reduce the risk? | Pecorella, G. De Rosa, F. Licchelli, M. Panese, G. Carugno, J. T. Morciano, A. Tinelli, A. | Int J Gynaecol Obstet | 2024 |
anesthesia |
| Serum NFL and tau, but not serum UCHL-1 and GFAP or CSF SNAP-25, NPTX2, or sTREM2, correlate with delirium in a 3-year retrospective analysis | Piel, J. H. A. Bargemann, L. Leypoldt, F. Wandinger, K. P. Dargvainiene, J. | Front Neurol | 2024 |
Alzheimer’s disease |
| Age-stratified comorbid and pharmacologic analysis of patients with glioblastoma | Rabin, E. E. Huang, J. Kim, M. Mozny, A. Lauing, K. L. Penco-Campillo, M. Zhai, L. Bommi, P. Mi, X. Power, E. A. Prabhu, V. C. Anderson, D. E. Barton, K. P. Walunas, T. L. Schiltz, G. E. Amidei, C. Sanchez-Gomez, P. Thakkar, J. P. Lukas, R. V. Wainwright, | Brain Behav Immun Health | 2024 |
Confusion |
| Unraveling the Predictors for Delirium and ICU Stay Duration in Patients with Heart Failure and Reduced Ejection Fraction (HFrEF) Undergoing Coronary Artery Bypass Grafting-A Multicentric Analysis | Rustenbach, C. J. Reichert, S. Berger, R. Schano, J. Nemeth, A. Haeberle, H. Charotte, C. Caldonazo, T. Saqer, I. Saha, S. Schnackenburg, P. Djordjevic, I. Krasivskyi, I. Wendt, S. Serna-Higuita, L. M. Doenst, T. Hagl, C. Wahlers, T. Schlensak, C. Sandova | Biomedicines | 2024 |
Cabg |
| Validation of the Delirium Observation Screening Scale in long-term care facilities in Flanders | Sabbe, K. van der Mast, R. Dilles, T. Van Rompaey, B. | Geriatr Gerontol Int | 2024 |
delirium |
| Effect of hospital elder life program on the incidence of delirium: A systematic review and meta-analysis of clinical trials | Shen, H. Liu, X. Wu, L. Jia, J. Jin, X. | Geriatr Nurs | 2024 |
Humans |
| Impact of Delirium Onset and Duration on Mortality in Patients With Cancer Admitted to the ICU | Tao, J. Seier, K. P. Chawla, S. Tan, K. S. Wheeler, A. Sanzone, J. Marasigan-Stone, C. B. Simondac, J. S. Pascual, A. V. Kostelecky, N. T. Voigt, L. P. | J Intensive Care Med | 2024 |
ICU outcomes |
| Interventions to prevent and treat delirium: An umbrella review of randomized controlled trials | Veronese, N. Solimando, L. Bolzetta, F. Maggi, S. Fiedorowicz, J. G. Gupta, A. Fabiano, N. Wong, S. Boyer, L. Fond, G. Dragioti, E. Dominguez, L. J. Barbagallo, M. Romagnoli, S. Bellelli, G. Solmi, M. | Ageing Res Rev | 2024 |
Delirium |
| Study on the causal relationship between educational attainment and delirium: A two-sample Mendelian randomization study | Wan, X. Yu, H. Yang, M. Hou, W. Xie, J. Xu, K. Ma, Y. Ma, R. Wang, F. Xu, P. | Heliyon | 2024 |
Delirium |
| Potential value of serum prealbumin and serum albumin in the identification of postoperative delirium in patients undergoing knee/hip replacement: an observational study and internal validation study | Wang, B. Xin, Y. Tang, X. Wang, F. Hua, S. Yang, Y. Xu, S. Gong, H. Dong, R. Lin, Y. Li, C. Lin, X. Bi, Y. | Front Neurol | 2024 |
biomarkers |
| Understanding the association between pain and delirium in older hospital inpatients: systematic review and meta-analysis | White, N. Bazo-Alvarez, J. C. Koopmans, M. West, E. Sampson, E. L. | Age Ageing | 2024 |
Humans |
| Prognostic value of Geriatric-8 for adverse outcomes within 30 days of surgery in older adults with colorectal cancer: A retrospective cohort study | Winters, A. M. Bakker, J. Ten Hoor, J. Bilo, H. J. G. Roodbol, P. F. Edens, M. A. Finnema, E. J. | Eur J Oncol Nurs | 2024 |
Cognitive decline |
| An online delirium detection tool: Cross-cultural adaptation of a Chinese version of the Family Confusion Assessment Method | Xing, H. Zhu, S. Liu, S. Xia, M. Tong, S. Li, L. Li, L. | Aust Crit Care | 2024 |
Delirium |
| Value of Flemish Version of the Triage Risk Screening Tool in Predicting Unfavorable Outcomes after Elective Cancer Surgery: A Propensity Score-Matched Retrospective Cohort Study | Yajima, S. Nakanishi, Y. Ogasawara, R. A. Imasato, N. Hirose, K. Katsumura, S. Kataoka, M. Masuda, H. | Biomed Hub | 2024 |
Delirium |
| Impact of intraoperative dexmedetomidine on postoperative delirium and pro-inflammatory cytokine levels in elderly patients undergoing thoracolumbar compression fracture surgery: A prospective, randomized, placebo-controlled clinical trial | Ye, C. Shen, J. Zhang, C. Hu, C. | Medicine (Baltimore) | 2024 |
Humans |
| Development and validation of a machine learning model to predict postoperative delirium using a nationwide database: A retrospective, observational study | Yoshimura, M. Shiramoto, H. Koga, M. Morimoto, Y. | J Clin Anesth | 2024 |
Machine learning model |
| Tau and delirium superimposed on dementia: A case report | Yu, P. C. Kuo, C. M. Chen, I. C. | SAGE Open Med Case Rep | 2024 |
Tau |
| Quetiapine Versus Haloperidol in the Management of Hyperactive Delirium: Randomized Controlled Trial | Zakhary, T. Ahmed, I. Luttfi, I. Montasser, M. | Neurocrit Care | 2024 |
Antipsychotics |
| Associations between postoperative cognitive dysfunction, serum interleukin-6 and postoperative delirium among patients after coronary artery bypass grafting: A mediation analysis | Zhang, S. Tao, X. J. Ding, S. Feng, X. W. Wu, F. Q. Wu, Y. | Nurs Crit Care | 2024 |
cardiac surgery |
| Risk prediction models for postoperative delirium in elderly patients with fragility hip fracture: A systematic review and critical appraisal | Zhou, B. Wang, A. Cao, H. | Int J Orthop Trauma Nurs | 2024 |
Humans |
| An exploratory study on the heterogeneity of postoperative delirium: Preoperative cognitive screening does not detect hallucinatory delirium risk | Yajima, S. Nakanishi, Y. Ogasawara, R. A. Imasato, N. Hirose, K. Katsumura, S. Kataoka, M. Masuda, H. | Eur J Surg Oncol | 2024 |
Humans |
| Validation of a viable delirium detection test performed by nurses and physicians during routine patient care | Soboh, R. Gino-Moor, S. Jiris, N. Ginsberg, S. Oliven, R. | BMC Geriatr | 2024 |
Humans |
| Does Comprehensive Geriatric Assessment Reduce the Incidence of Postoperative Delirium? A Quasi-experimental Study in Older Adults Undergoing Transcatheter Aortic Valve Implantation | Schwesinger, A. Tsai, L. T. Lang, W. Mantegazza, N. Bauernschmitt, R. Wilhelm, M. J. Bischoff-Ferrari, H. A. Gagesch, M. | Clin Interv Aging | 2024 |
Humans |
| Butyrylcholinesterase activity in patients with postoperative delirium after cardiothoracic surgery or percutaneous valve replacement- an observational interdisciplinary cohort study | Schlake, K. Teller, J. Hinken, L. Laser, H. Lichtinghagen, R. Schäfer, A. Fegbeutel, C. Weissenborn, K. Jung, C. Worthmann, H. Gabriel, M. M. | BMC Neurol | 2024 |
Aged |
| Diagnostic accuracy of the pediatric CAM-ICU, pre-school CAM-ICU, Pediatric Anesthesia Emergence Delirium and Cornell Assessment of Pediatric Delirium for detecting delirium in the pediatric intensive care unit: A systematic review and meta-analysis | Rohmah, I. Chen, Y. C. Lin, C. J. Tsao, N. H. Chiu, H. Y. | Intensive Crit Care Nurs | 2024 |
Humans |
| Intraoperative Use of Phenylephrine versus Ephedrine and Postoperative Delirium: A Multicenter Retrospective Cohort Study | Ma, H. Ahrens, E. Wachtendorf, L. J. Suleiman, A. Shay, D. Munoz-Acuna, R. Tartler, T. M. Teja, B. Wagner, S. Subramaniam, B. Rhee, J. Schaefer, M. S. | Anesthesiology | 2024 |
Adult |
| Effect of clock rhythm on emergence agitation and early postoperative delirium in older adults undergoing thoracoscopic lung cancer surgery: protocol for a prospective, observational, cohort study | Jiang, L. Wang, J. Chen, W. Wang, Z. Xiong, W. | BMC Geriatr | 2024 |
Humans |
| Scientific rationale for the use of α2A-adrenoceptor agonists in treating neuroinflammatory cognitive disorders | Arnsten, A. F. T. Ishizawa, Y. Xie, Z. | Mol Psychiatry | 2023 |
Humans |
| The role of perioperative sedative anesthetics in preventing postoperative delirium: a systematic review and network-meta analysis including 6679 patients | Huang, J. X. Zhang, S. S. Wang, S. X. Xi, D. S. Luo, F. R. Liu, C. J. Li, H. | BMC Cardiovasc Disord | 2024 |
PMID: 38448835 PMCID: PMC10916082 |
| Preventive Effects of Melatonin on Delirium in Intensive Care Unit Patients: A Meta-Analysis of Randomized Controlled Trials | Zhao, L. Feng, Z. Wang, Q. Jiang, Z. Qiu, X. | Altern Ther Health Med | 2024 |
ICU Delirium Melatonin Length of Stay Meta-Analysis Mechanical Ventilation |
| Mitochondrial Dysfunction of Peripheral Platelets as a Predictive Biomarker for Postoperative Delirium in Elderly Patients | Yang, Y. Zhang, W. Liu, Y. Liu, X. Xie, J. Xu, R. Huang, Y. Hao, J. Sun, Y. Gu, X. Ma, Z. | Ann Neurol | 2024 |
Postoperative Delirium Bioenergetic Health Index Surgery Mitochondria MMSE
|
| Effect of Esketamine on Postoperative Delirium in Patients Undergoing Cardiac Valve Replacement with Cardiopulmonary Bypass: A Randomized Controlled Trial | Xiong, X. Shao, Y. Chen, D. Chen, B. Lan, X. Shi, J. | Anesth Analg | 2024 |
Postoperative Delirium Esketamine Cardiac Valve Replacement Cardiopulmonary Bypass CAM CAM-ICU MMSE |
| Prolonged Hourly Neurologic Examinations are Associated with Increased Delirium and No Discernible Benefit in Mild/Moderate Geriatric Traumatic Brain Injury | Ruiz, R. A. F. Canas, M. Diaz, L. Aldana, J. A. Afzal, H. Falcon, A. F. Del Toro, D. Day, A. McCarthy, J. Stansfield, K. Bochicchio, G. V. Niziolek, G. Kranker, L. M. Rosengart, M. R. Hoofnagle, M. Leonard, J. | J Trauma Acute Care Surg | 2024 |
NeuroChecks Delirium TBI CAM-ICU |
| Association of Intravenous Neostigmine and Anticholinergics or Sugammadex with Postoperative Delirium: A Retrospective Cohort Study | Rössler, J. Abramczyk, E. Paredes, S. Anusic, N. Pu, X. Maheshwari, K. Turan, A. Ruetzler, K. | Anesth Analg | 2024 |
bCAM Postoperative Delirium Sugammadex Neostigmine Anesthesia Noncardiac Surgery |
| Metformin Use in Type 2 Diabetics and Delirium After Noncardiac Surgery: A Retrospective Cohort Analysis | Paredes, S. Harb, A. Rössler, J. Nikoo, M. Z. Ruetzler, K. Turan, A. Pu, X. Sessler, D. I. | Anesth Analg | 2024 |
Type 2 Diabetes CAM-ICU bCAM Postoperative Delirium Metformin
|
| Preoperative Intrathecal Morphine is Associated With Reduced Postoperative Pain, Agitation, and Delirium In Living Donor Kidney Transplantation Recipients | Lee, J. E. Lee, K. W. Gil, E. Park, J. B. Kim, B. J. Kim, H. Y. Kim, G. S. | Transplant Proc | 2024 |
Kidney Transplant Postoperative Delirium Intrathecal Morphine CAM-ICU Postoperative Pain Anesthesia |
| Neuropsychological follow-up of isoflurane sedated intensive care patients: a substudy of a randomized trial | Fuchs, V. F. Simon, H. V. Soldinger, N. Volk, T. Meiser, A. | Minerva Anestesiol | 2024 |
Critical care Isoflurane Propofol Delirium |
| Feasibility and Acceptability of Using Wireless Limited Polysomnography to Capture Sleep Before, During, and After Hospitalization for Patients With Planned Cardiothoracic Surgery | Cordoza, M. L. Anderson, B. J. Cevasco, M. Diamond, J. M. Younes, M. Gerardy, B. Iroegbu, C. Riegel, B. | J Cardiovasc Nurs | 2024 |
Critical Illness Intensive Care Unit Polysomnography Sleep Thoracic Surgery |
| Antipsychotics in the Treatment of Delirium in Critically Ill Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials | Carayannopoulos, K. L. Alshamsi, F. Chaudhuri, D. Spatafora, L. Piticaru, J. Campbell, K. Alhazzani, W. Lewis, K. | Crit Care Med | 2024 |
Antipsychotic medication Delirium Systematic review Critically Ill Cognitive Impairment Coma |
| Burnout and perceived burden levels related to delirium in physicians and nurses | Yamagata, H. Takihara, T. Kobayashi, R. Hirose, K. Higuchi, K. Miyahara, M. Komatsu, D. | Gen Hosp Psychiatry | 2024 |
Humans |
| Bell's mania as a clinical presentation in a neurosurgical setting from a tertiary care neuropsychiatric hospital in India | Mamtani, H. Utagi, S. Chaurasia, K. K. Reddy, P. V. Arasappa, R. Prasad, C. Srinivas, D. Rao, M. B. Thippeswamy, H. | Indian J Psychiatry | 2024 |
Craniopharyngioma |
| Correlation analysis between plasma biomarkers albumin, fibrinogen, and their ratio with postoperative delirium in patients undergoing non-cardiac surgery: a systematic review and meta-analysis | Lu, Z. Wang, B. Liu, M. Yu, D. Li, J. | Am J Transl Res | 2024 |
Albumin |
| Risk factors for hypoactive delirium in patients with nontraumatic ARDS: a prospective observational study | Lian, F. Li, F. Tang, X. Yuan, Y. | Sci Rep | 2024 |
Humans |
| Current Practices and Attitudes of Cardiac Nurses Regarding Cognitive Screening in Patients With Acute Coronary Syndrome | Zhao, E. Lowres, N. Bloomfield, J. Weddell, J. Tofler, G. Gallagher, R. | Heart Lung Circ | 2024 |
Acute coronary syndrome |
| Related factors of delirium after transsphenoidal endoscopic pituitary adenoma resection-A matched retrospective cohort study | Zhang, S. Chen, Y. Wang, X. Liu, J. Chen, Y. Zhang, G. | J Clin Neurosci | 2024 |
Neuroendoscopy |
| Prevalence of post-stroke delirium in acute settings: A systematic review and meta-analysis | Ye, F. Ho, M. H. Lee, J. J. | Int J Nurs Stud | 2024 |
Acute setting |
| Predictive factors for postoperative delirium in thoracic surgery | Yaguchi, T. Ichinokawa, H. Kirino, E. Suzuki, M. Komori, K. Matsunaga, T. Takamochi, K. Suzuki, K. | Gen Thorac Cardiovasc Surg | 2024 |
Postoperative delirium |
| Preoperative cognitive impairment and postoperative delirium among Holocaust survivors who achieved longevity | Weiss, Y. Zarour, S. Kiselevich, Y. Abu Ghanim, M. Hikry, D. Sinai Brzezinski, I. Zac, L. Cohen, B. Matot, I. | J Am Geriatr Soc | 2024 |
Holocaust |
| Substance use problems and disorders among adults 50 years and older receiving mental health treatment for a primary neurocognitive disorder | Ware, O. D. Baik, S. Becker, T. D. Neukrug, H. Zimmerman, S. | Aging Ment Health |
Aging |
|
| The risk of delirium after sedation with propofol or midazolam in intensive care unit patients | van Gelder, T. G. van Diem-Zaal, I. J. Dijkstra-Kersten, S. M. A. de Mul, N. Lalmohamed, A. Slooter, A. J. C. | Br J Clin Pharmacol | 2024 |
critical care |
| Incidence and Risk Factors for ICU-Associated Delirium in the Alert Geriatric Trauma Population | Ulderich Williams, S. C. Qaddoumi, A. I. Meghreblian, J. T. McBride, M. E. King, S. A. Elahi, M. A. Tuggle, D. Heidel, R. E. Smith, L. M. | Am Surg | 2024 |
Glasgow Coma Score |
| Opioid use and subsequent delirium risk in patients with advanced cancer in palliative care: a multicenter registry study | Yoo, S. H. Kang, J. Kim, H. J. Lee, S. W. Hong, M. Jung, E. H. Kim, Y. J. Yon, D. K. Kang, B. | Sci Rep | 2024 |
Humans |
| Point prevalence and clinical profile of patients with delirium admitted in internal medicine department at tertiary care centre in eastern Nepal: a descriptive cross-sectional study | Yogi, T. N. Puri, S. Shah, B. Nepal, S. Mishra, A. | Ann Med Surg (Lond) | 2024 |
alcoholism |
| Reducing the use of psychotropics in a convalescent rehabilitation ward | Uematsu, T. Tomita, T. Obara, R. Gonai, T. Hattori, K. Aonuma, T. Usui, K. Tanifuji, H. Ishizawa, F. Ishii, H. Suzuki, E. | Neuropsychopharmacol Rep | 2024 |
Humans |
| The impact of postoperative agitated delirium on dementia in surgical patients | Sun, M. Chen, W. M. Wu, S. Y. Zhang, J. | Brain Commun | 2024 |
Psm |
| The impact of postoperative agitated delirium on dementia in surgical patients | Sun, M. Chen, W. M. Wu, S. Y. Zhang, J. | Brain Commun | 2024 |
Psm |
| Effects of human herpesvirus 6B reactivation on cognitive function in cord blood transplant recipients: a prospective multicenter study | Ogata, M. Oshima, K. Takano, K. Kawano, R. Ueda, Y. Imamura, T. Nakamura, Y. Okada, T. Toubai, T. Ueki, T. Uoshima, N. Ishida, H. Shinohara, A. Seo, S. Fukuda, T. Inagaki, M. | Int J Hematol | 2024 |
Humans |
| Modification in ICU Design May Affect Delirium and Circadian Melatonin: A Proof of Concept Pilot Study | Spies, C. Piazena, H. Deja, M. Wernecke, K. D. Willemeit, T. Luetz, A. | Crit Care Med | 2024 |
Adult |
| The effect of nonpharmacological interventions applied by nurses to intensive care patients on the duration of delirium: a meta-analysis study | Söylemez, G. K. Uzun, S. | Ir J Med Sci | 2024 |
Humans |
| Prevalence, risk factors and impact of delirium in adult inpatients in a tertiary care hospital: A point prevalence study | Schiess, C. Hofer, L. Von Felten, S. Bartussek, J. Petry, H. Ernst, J. | J Clin Nurs | 2024 |
cross-sectional studies |