What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Safety and Tolerability of Rapid Administration Undiluted Levetiracetam
- Authors
- Morgan, O. Medenwald, B.
- Year
- 2020
- Journal
- Neurocrit Care
- Abstract
BACKGROUND/OBJECTIVE: Levetiracetam (LEV) is an antiepileptic drug used widely in patients with a favorable safety profile. Studies evaluating the safety and efficacy of intravenous (IV) LEV included volumes of at least 100 mL. Minimally diluted doses administered over 5-6 min were found to be both safe and effective. Given the complexities of admixing, this practice can be impractical and result in delays in antiepileptic therapy. This study aimed to retrospectively review the safety and tolerability of rapid administration of undiluted LEV doses </= 1000 mg. METHODS: This was a retrospective study evaluating adverse drug reactions associated with undiluted LEV from January 1, 2018-June 1, 2018. Patients were included if they received at least one dose of undiluted LEV and were >/= 18 years old. Safety endpoints were reviewed and collected from the time administration until hospital discharge. Endpoints included injection site pain and discomfort, injection site erythema, extravasation, IV line replacement, and any documented adverse effect leading to IV LEV discontinuation. Descriptive statistics were used to analyze the data. RESULTS: A total of 199 patients were included in the study totaling 1626 doses of LEV. Most patients were administered LEV 1000 mg (60.8%), through a peripheral line (64.3%), and were prescribed LEV for seizure prophylaxis (58.3%). Patients received a mean of 8.1 +/- 8 doses for a mean duration of therapy of 5 +/- 4.5 days. About 98.5% of patients did not experience an adverse effect, whereas 1.5% of patients experienced agitation, delirium, confusion, and/or lethargy, which is well known to LEV therapy. CONCLUSIONS: Rapid administration of undiluted LEV doses </= 1000 mg were well tolerated with no concentration-related side effects. Further prospective research is needed to confirm this observation as well as the safety of higher doses.
- PMID
- Keywords
Anticonvulsants
Humans
Intravenous
- Page(s)
- 131-134
- Volume
- 32
- Issue
- 1
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| The efficacy of antipsychotics for prolonged delirium with renal dysfunction. | Asano, S. Kunii, Y. Hoshino, H. Osakabe, Y. Shiga, T. Itagaki, S. Miura, I. Yabe, H. | Neuropsychiatr Dis Treat | 2017 |
antipsychotic |
| Comparison of the effect of high versus low mean arterial pressure levels on clinical outcomes and complications in elderly patients during non-cardiothoracic surgery under general anesthesia: study protocol for a randomized controlled trial. | Anmin, Hu Yan, Qiu Peng, Zhang Bailong, Hu Yali, Yang Shutao, Li Rui, Zhao Zhongjun, Zhang Yaoxian, Zhang Zihao, Zheng Chen, Qiu Furong, Li Xiaolei, Gong Hu, Anmin Qiu, Yan Zhang, Peng Hu, Bailong Yang, Yali Li, Shutao Zhao, Rui | Trials | 2017 | |
| Association between baseline cognitive impairment and postoperative delirium in elderly patients undergoing surgery for adult spinal deformity. | Adogwa, O. Elsamadicy, A. A. Vuong, V. D. Fialkoff, J. Cheng, J. Karikari, I. O. Bagley, C. A. | J Neurosurg Spine | 2017 |
CAM = Confusion Assessment Method |
| Effect of the Hospital Elder Life Program on Risk of 30-Day Readmission. | Rubin, F. H. Bellon, J. Bilderback, A. Urda, K. Inouye, S. K. | Journal of the American Geriatrics Society | 2017 |
aged |
| Clinical outcomes in older surgical patients with mild cognitive impairment. | Racine, A. M. Fong, T. G. Gou, Y. Travison, T. G. Tommet, D. Erickson, K. Jones, R. N. Dickerson, B. C. Metzger, E. Marcantonio, E. R. Schmitt, E. M. Inouye, S. K. | Alzheimers Dement | 2017 |
Mild cognitive impairment |
| Prediction of Long-term Cognitive Decline Following Postoperative Delirium in Older Adults. | Devore EE, Fong TG, Marcantonio ER, Schmitt EM, Travison TG, Jones RN, Inouye SK | The journals of gerontology. Series A, Biological sciences and medical sciences | 2017 |
Aged |
| The Cognitive Reserve Model in the Development of Delirium: The Successful Aging After Elective Surgery Study. | Cizginer, S. Marcantonio, E. Vasunilashorn, S. Pascual-Leone, A. Shafi, M. Schmitt, E. M. Inouye, S. K. Jones, R. N. | J Geriatr Psychiatry Neurol | 2017 |
delirium |
| Incidence of Delirium Among Patients Having Cancer Injected With Different Opioids for the First Time. | Tanaka R, Ishikawa H, Sato T, Shino M, Matsumoto T, Mori K, Omae K, Osaka I | The American journal of hospice & palliative care | 2016 |
delirium |
| Complications after hip fracture surgery: are they preventable? | Flikweert, E. R. Wendt, K. W. Diercks, R. L. Izaks, G. J. Landsheer, D. Stevens, M. Reininga, I. H. F. | Eur J Trauma Emerg Surg | 2017 |
Complications |
| Pilot prospective study of post-surgery sleep and EEG predictors of post-operative delirium. | Evans, J. L. Nadler, J. W. Preud'homme, X. A. Fang, E. Daughtry, R. L. Chapman, J. B. Attarian, D. Wellman, S. Krystal, A. D. | Clin Neurophysiol | 2017 |
Aged |
| Development of an international undergraduate curriculum for delirium using a modified delphi process. | Copeland, C. Fisher, J. Teodorczuk, A. | Age Ageing | 2017 |
curriculum |
| Serum galectin-3 levels and delirium among postpartum intensive care unit women. | Zhu, Y. Hu, W. Zhu, M. L. Yin, T. Su, J. Wang, J. R. | Brain Behav | 2017 |
delirium |
| Characteristics of patients with an unplanned admission to an acute palliative care unit. | Mercadante, S. Adile, C. Ferrera, P. Casuccio, A. | Intern Emerg Med | 2017 |
Cancer |
| FRAIL Questionnaire Screening Tool and Short-Term Outcomes in Geriatric Fracture Patients. | Gleason, L. J. Benton, E. A. Alvarez-Nebreda, M. L. Weaver, M. J. Harris, M. B. Javedan, H. | J Am Med Dir Assoc | 2017 |
Frailty |
| Disruption of the ascending arousal system and cortical attention networks in post-stroke delirium and spatial neglect. | Boukrina, O. Barrett, A. M. | Neurosci Biobehav Rev | 2017 |
Aras |
| Incidence of delirium after cardiac surgery: protocol for the DELIRIUM-CS Canada cross-sectional cohort study. | DELIRIUM-CS Investigators, Canadian Cardiovascular Critical Care Society Investigator Group and the Canadian Critical Care Trials Group | CMAJ Open | 2017 | |
| Preoperative C-Reactive Protein as a Risk Factor for Postoperative Delirium in Elderly Patients Undergoing Laparoscopic Surgery for Colon Carcinoma. | Xiang, Dong Xing, Hailin Tai, Huiyu Xie, Guozhu | BioMed Research International | 2017 | |
| Responding to Ten Common Delirium Misconceptions With Best Evidence: An Educational Review for Clinicians. | Oldham, M. A. Flanagan, N. M. Khan, A. Boukrina, O. Marcantonio, E. R. | J Neuropsychiatry Clin Neurosci | 2017 |
Cognitive Disorders |
| The network model of delirium. | Young JWS | Medical hypotheses | 2017 |
Default-mode network |
| Aging and Post-Intensive Care Syndrome: A Critical Need for Geriatric Psychiatry. | Wang, S. Allen, D. Kheir, Y. N. Campbell, N. Khan, B. | Am J Geriatr Psychiatry | 2017 |
Aging |
| Intensive care discharge delay is associated with increased hospital length of stay: A multicentre prospective observational study. | Tiruvoipati, R. Botha, J. Fletcher, J. Gangopadhyay, H. Majumdar, M. Vij, S. Paul, E. Pilcher, D. | PLoS One | 2017 |
Adolescent |
| How can we identify patients with delirium in the emergency department?: A review of available screening and diagnostic tools. | Tamune H, Yasugi D | The American journal of emergency medicine | 2017 |
Aged |
| Symptom profile as assessed on delirium rating scale-revised-98 of delirium in respiratory intensive care unit: A study from India. | Sharma, A. Malhotra, S. Grover, S. Jindal, S. K. | Lung India | 2017 | |
| Burst-suppression ratio underestimates absolute duration of electroencephalogram suppression compared with visual analysis of intraoperative electroencephalogram. | Muhlhofer, W. G. Zak, R. Kamal, T. Rizvi, B. Sands, L. P. Yuan, M. Zhang, X. Leung, J. M. | Br J Anaesth | 2017 | |
| Post-anaesthesia care unit delirium: incidence, risk factors and associated adverse outcomes. | Hernandez, B. A. Lindroth, H. Rowley, P. Boncyk, C. Raz, A. Gaskell, A. Garcia, P. S. Sleigh, J. Sanders, R. D. | Br J Anaesth | 2017 | |
| Validation of the 4AT questionnaire in the emergency department | Gagné, A. Voyer, P. Boucher, V. Pelletier, M. Gouin, E. Berthelot, S. Daoust, R. Laguë, A. Bédard, C. Émond, M. | Canadian Journal of Emergency Medicine | 2017 |
aged |
| Incidence, prognostic factors and impact of postoperative delirium after major vascular surgery: A meta-analysis and systematic review. | Aitken, S. J. Blyth, F. M. Naganathan, V. | Vasc Med | 2017 |
aging |
| Altered cortical brain activity in end stage liver disease assessed by multi-channel near-infrared spectroscopy: Associations with delirium. | Yoshimura, A. Goodson, C. Johns, J. T. Towe, M. M. Irvine, E. S. Rendradjaja, N. A. Max, L. K. LaFlam, A. Ledford, E. C. Probert, J. Tieges, Z. Edwin, D. H. MacLullich, A. M. J. Hogue, C. W. Lindquist, M. A. Gurakar, A. Neufeld, K. J. Kamiya, A. | Sci Rep | 2017 | |
| Comprehensive geriatric care reduces acute perioperative delirium in elderly patients with hip fractures: A meta-analysis. | Wang, Y. Tang, J. Zhou, F. Yang, L. Wu, J. | Medicine | 2017 |
Aged |
| Effect of nocturnal sound reduction on the incidence of delirium in intensive care unit patients: An interrupted time series analysis. | van de Pol, I. van Iterson, M. Maaskant, J. | Intensive Crit Care Nurs | 2017 |
Aged |
| Poorer outcomes and greater healthcare costs for hospitalised older people with dementia and delirium: a retrospective cohort study. | Tropea J, LoGiudice D, Liew D, Gorelik A, Brand C | International journal of geriatric psychiatry | 2017 |
dementia |
| Attitudes, knowledge and practices concerning delirium: a survey among intensive care unit professionals. | Trogrlić, Zoran Ista, Erwin Ponssen, Huibert H. Schoonderbeek, Jeannette F. Schreiner, Frodo Verbrugge, Serge J. Dijkstra, Annemieke Bakker, Jan Jagt, Mathieu | Nursing in Critical Care | 2017 |
Attitude of Health Personnel |
| Can we predict a delirium after cardiac surgery? A validation study of a delirium risk checklist. | Ten Broeke, M. Koster, S. Konings, T. Hensens, A. G. van der Palen, J. | Eur J Cardiovasc Nurs | 2017 |
Delirium |
| Suvorexant is associated with a low incidence of delirium in critically ill patients: a retrospective cohort study. | Masuyama, T. Sanui, M. Yoshida, N. Iizuka, Y. Ogi, K. Yagihashi, S. Nagatomo, K. Sasabuchi, Y. Lefor, A. K. | Psychogeriatrics | 2018 |
critically ill |
| Do Risk Prediction Models for Postoperative Delirium Consider Patients' Preoperative Medication Use? | Kassie, G. M. Nguyen, T. A. Kalisch Ellett, L. M. Pratt, N. L. Roughead, E. E. | Drugs Aging | 2018 | |
| Predictors and Outcomes of Cardiac Surgery-Associated Delirium. A Single Centre Retrospective Cohort Study. | Jones, D. Matalanis, G. Martensson, J. Robbins, R. Shaw, M. Seevanayagam, S. Cowie, D. Bellomo, R. | Heart Lung Circ | 2018 |
Cardiac surgery |
| Delirium in older hospitalized patients-signs and actions: a retrospective patient record review. | Johansson, Y. A. Bergh, I. Ericsson, I. Sarenmalm, E. K. | BMC Geriatr | 2018 |
*Action by healthcare professionals |
| Delirium-A Framework to Improve Acute Care for Older Persons. | Inouye, S. K. | J Am Geriatr Soc | 2018 |
Acute care for elders |
| The minimal clinically important difference of the Richmond Agitation-Sedation Scale in patients with cancer with agitated delirium. | Hui, D. Hess, K. Dibaj, S. S. Arthur, J. Dev, R. Dalal, S. Reddy, S. Bruera, E. | Cancer | 2018 |
delirium |
| The use of cerebral imaging for investigating delirium aetiology. | Hijazi, Z. Lange, P. Watson, R. Maier, A. B. | Eur J Intern Med | 2018 |
Delirium |
| Medication Profiles of Patients with Cognitive Impairment and High Anticholinergic Burden. | Green, A. R. Reifler, L. M. Boyd, C. M. Weffald, L. A. Bayliss, E. A. | Drugs Aging | 2018 | |
| Delirium Assessment Tools for Use in Critically Ill Adults: A Psychometric Analysis and Systematic Review. | Gelinas, C. Berube, M. Chevrier, A. Pun, B. T. Ely, E. W. Skrobik, Y. Barr, J. | Crit Care Nurse | 2018 | |
| Postoperative Delirium in Glioblastoma Patients: Risk Factors and Prognostic Implications. | Flanigan, P. M. Jahangiri, A. Weinstein, D. Dayani, F. Chandra, A. Kanungo, I. Choi, S. Sankaran, S. Molinaro, A. M. McDermott, M. W. Berger, M. S. Aghi, M. K. | Neurosurgery | 2018 | |
| The delirium and population health informatics cohort study protocol: ascertaining the determinants and outcomes from delirium in a whole population. | Davis, D. Richardson, S. Hornby, J. Bowden, H. Hoffmann, K. Weston-Clarke, M. Green, F. Chaturvedi, N. Hughes, A. Kuh, D. Sampson, E. Mizoguchi, R. Cheah, K. L. Romain, M. Sinha, A. Jenkin, R. Brayne, C. MacLullich, A. | BMC Geriatr | 2018 |
*Delirium |
| Cerebral oximetry during preoperative resuscitation in elderly patients with hip fracture: a prospective observational study. | Clemmesen, C. G. Pedersen, L. M. Hougaard, S. Andersson, M. L. Rosenkvist, V. Nielsen, H. B. Palm, H. Foss, N. B. | J Clin Monit Comput | 2018 |
Delirium |
| Clinical characteristics associated with the onset of delirium among long-term nursing home residents. | Cheung, E. N. M. Benjamin, S. Heckman, G. Ho, J. M. Lee, L. Sinha, S. K. Costa, A. P. | BMC Geriatr | 2018 |
*Delirium |
| Evaluation of a multicomponent pathway to address inpatient delirium on a neurosciences ward. | Brown, E. G. Josephson, S. A. Anderson, N. Reid, M. Lee, M. Douglas, V. C. | BMC Health Serv Res | 2018 |
*Cognitive aging |
| Subsyndromal delirium in the intensive care setting: Phenomenological characteristics and discrimination of subsyndromal delirium versus no and full-syndromal delirium. | Boettger S, Nuñez DG, Meyer R, Richter A, Schubert M, Jenewein J | Palliative & supportive care | 2017 |
Diagnostic and Statistical Manual of Mental Disorders |
| Incidence, risk factors, and clinical implications of post-operative delirium in lung transplant recipients. | Anderson, B. J. Chesley, C. F. Theodore, M. Christie, C. Tino, R. Wysoczanski, A. Ramphal, K. Oyster, M. Kalman, L. Porteous, M. K. Bermudez, C. A. Cantu, E. Kolson, D. L. Christie, J. D. Diamond, J. M. | J Heart Lung Transplant | 2018 |
acidic protein |
| Delirium and correlates of delirium among newly admitted elderly patients: A crosssectional study in a Saudi general hospital. | Alamri, S. H. Ashanqity, O. A. Alshomrani, A. B. Elmasri, A. H. Saeed, M. B. Yahya, S. A. Almasoud, A. I. Adam, Y. Alamoudi, H. M. Mukhtar, A. M. | Annals of Saudi Medicine | 2018 |
urinary catheter |
| Preoperative Cognitive Impairment As a Predictor of Postoperative Outcomes in a Collaborative Care Model. | Zietlow, K. McDonald, S. R. Sloane, R. Browndyke, J. Lagoo-Deenadayalan, S. Heflin, M. T. | J Am Geriatr Soc | 2018 |
co-management |
| Identifying Older Adults at Risk of Delirium Following Elective Surgery: A Systematic Review and Meta-Analysis. | Watt, J. Tricco, A. C. Talbot-Hamon, C. Pham, B. Rios, P. Grudniewicz, A. Wong, C. Sinclair, D. Straus, S. E. | J Gen Intern Med | 2018 |
delirium |
| Sedative Plasma Concentrations and Delirium Risk in Critical Illness. | Stollings, J. L. Thompson, J. L. Ferrell, B. A. Scheinin, M. Wilkinson, G. R. Hughes, C. G. Shintani, A. K. Ely, E. W. Girard, T. D. Pandharipande, P. P. Patel, M. B. | Ann Pharmacother | 2018 |
analgesics |
| A feasibility study of a randomised controlled trial to examine the impact of the ABCDE bundle on quality of life in ICU survivors. | Sosnowski, K. Mitchell, M. L. White, H. Morrison, L. Sutton, J. Sharratt, J. Lin, F. | Pilot Feasibility Stud | 2018 |
ABCDE bundle |
| Potentially Modifiable Risk Factors for Long-Term Cognitive Impairment After Critical Illness: A Systematic Review. | Sakusic, A. O'Horo, J. C. Dziadzko, M. Volha, D. Ali, R. Singh, T. D. Kashyap, R. Farrell, A. M. Fryer, J. D. Petersen, R. Gajic, O. Rabinstein, A. A. | Mayo Clin Proc | 2018 | |
| Prevalence of Potentially Inappropriate Medication Use in Older Inpatients with and without Cognitive Impairment: A Systematic Review. | Redston, M. R. Hilmer, S. N. McLachlan, A. J. Clough, A. J. Gnjidic, D. | J Alzheimers Dis | 2018 |
Cognitive impairment |
| Identification of delirium and dementia in older medical inpatients in Tanzania: A comparison of screening and diagnostic methods. | Paddick, S. M. Lewis, E. G. Duinmaijer, A. Banks, J. Urasa, S. Tucker, L. Kisoli, A. Cletus, J. Lissu, C. Kissima, J. Dotchin, C. Gray, W. K. Muaketova-Ladinska, E. Cosker, G. Walker, R. W. | Journal of the Neurological Sciences | 2018 |
adult |
| Interactions between drugs and geriatric syndromes in nursing home and home care: results from Shelter and IBenC projects. | Onder, G. Giovannini, S. Sganga, F. Manes-Gravina, E. Topinkova, E. Finne-Soveri, H. Garms-Homolova, V. Declercq, A. van der Roest, H. G. Jonsson, P. V. van Hout, H. Bernabei, R. | Aging Clinical and Experimental Research | 2018 |
Delirium |
| Development of dementia in patients with femoral neck fracture who experience postoperative delirium-A three-year follow-up study. | Olofsson, B. Persson, M. Bellelli, G. Morandi, A. Gustafson, Y. Stenvall, M. | Int J Geriatr Psychiatry | 2018 |
cognitive impairment |
| Prediction and early detection of delirium in the intensive care unit by using heart rate variability and machine learning. | Oh, J. Cho, D. Park, J. Na, S. H. Kim, J. Heo, J. Shin, C. S. Kim, J. J. Park, J. Y. Lee, B. | Physiol Meas | 2018 |
Autonomic nervous system |
| Preoperative exercise capacity is associated with the prevalence of postoperative delirium in elective cardiac surgery. | Ogawa M, Izawa KP, Satomi-Kobayashi S, Kitamura A, Tsuboi Y, Komaki K, Ono R, Sakai Y, Tanaka H, Okita Y | Aging clinical and experimental research | 2017 |
Cardiac surgery |
| Effectiveness of multicomponent interventions on incidence of delirium in hospitalized older patients with hip fracture: a systematic review. | Oberai, T. Laver, K. Crotty, M. Killington, M. Jaarsma, R. | Int Psychogeriatr | 2018 |
Delirium-elderly patients |
| Controlled pre-post, mixed-methods study to determine the effectiveness of a national delirium clinical care standard to improve the diagnosis and care of patients with delirium in Australian hospitals: a protocol. | Mumford, V. Kulh, M. A. Hughes, C. Braithwaite, J. Westbrook, J. | BMJ Open | 2018 |
clinical governance |
| Incidence and Risk Factors of Postoperative Delirium following Pancreatic Surgery: Does the Administration of TJ-54 Reduce the Incidence of Delirium. | Mizuno, S. Takeuchi, S. Kishiwada, M. Mizutani, N. Matsuda, M. Sekoguchi, N. Iizawa, Y. Azumi, Y. Kuriyama, N. Usui, M. Sakurai, H. Maruyama, K. Okuda, M. Okada, M. Isaji, S. | Dig Surg | 2018 |
Delirium rating scale – Japanese version |
| Association of Integrated Care Coordination With Postsurgical Outcomes in High-Risk Older Adults: The Perioperative Optimization of Senior Health (POSH) Initiative. | McDonald, S. R. Heflin, M. T. Whitson, H. E. Dalton, T. O. Lidsky, M. E. Liu, P. Poer, C. M. Sloane, R. Thacker, J. K. White, H. K. Yanamadala, M. Lagoo-Deenadayalan, S. A. | JAMA Surg | 2018 | |
| Effect of motor subtypes of delirium in the intensive care unit on fast-track failure after cardiac surgery | Lee, A. Mu, J. L. Chiu, C. H. Gin, T. Underwood, M. J. Joynt, G. M. | J Thorac Cardiovasc Surg | 2018 |
cardiac surgical procedures |
| Preoperative medication use and its association with postoperative length of hospital stay in surgical oncology patients receiving comprehensive geriatric assessment. | Jeong, Y. M. Lee, K. E. Lee, E. S. Kim, K. I. Chung, J. E. Lee, B. K. Gwak, H. S. | Geriatrics & Gerontology International | 2018 |
comprehensive geriatric assessment |
| Postoperative Delirium in Cardiac Surgery Patients. | Järvelä, K. Porkkala, H. Karlsson, S. Martikainen, T. Selander, T. Bendel, S. | Journal of Cardiothoracic and Vascular Anesthesia | 2018 |
aged |
| “Eight Days of Nightmares … ” – Octogenarian Patients’ Experiences of Postoperative Delirium after Transcatheter or Surgical Aortic Valve Replacement. | Instenes, I. Gjengedal, E. Eide, L. S. P. Kuiper, K. K. J. Ranhoff, A. H. Norekvål, T. M. | Heart Lung and Circulation | 2018 |
aged |
| General Anesthesia for Transcatheter Aortic Valve Replacement: Total Intravenous Anesthesia is Associated with Less Delirium as Compared to Volatile Agent Technique. | Goins, A. E. Smeltz, A. Ramm, C. Strassle, P. D. Teeter, E. G. Vavalle, J. P. Kolarczyk, L. | Journal of Cardiothoracic and Vascular Anesthesia | 2018 |
adult |
| The use of point-of-care ultrasound to diagnose patent foramen ovale in elective hip and knee arthroplasty patients and its association with postoperative delirium. | Gai, N. Lavi, R. Jones, P. M. Lee, H. Naudie, D. Bainbridge, D. | Can J Anaesth | 2018 | |
| Comparison of Lurasidone Versus Quetiapine for the Treatment of Delirium in Critically Ill Patients. | Fox, M. A. Elefritz, J. L. Huang, B. M. Hunley, C. | J Intensive Care Med | 2018 |
atypical antipsychotic |
| Key components of the delirium syndrome and mortality: greater impact of acute change and disorganised thinking in a prospective cohort study. | Diwell, R. A. Davis, D. H. Vickerstaff, V. Sampson, E. L. | BMC Geriatr | 2018 |
*delirium |
| Postoperative Delirium in Indian Patients Following Major Abdominal Surgery for Cancer: Risk Factors and Associations. | Dhakharia, V. Sinha, S. Bhaumik, J. | Indian J Surg Oncol | 2017 |
Cancer |
| Effect of an interactive E-learning tool for delirium on patient and nursing outcomes in a geriatric hospital setting: findings of a before-after study. | Detroyer, E. Dobbels, F. Teodorczuk, A. Deschodt, M. Depaifve, Y. Joosten, E. Milisen, K. | BMC Geriatr | 2018 |
*Delirium |
| Melatonin and the Prevention and Management of Delirium: A Scoping Study. | Choy, S. W. Yeoh, A. C. Lee, Z. Z. Srikanth, V. Moran, C. | Front Med | 2017 |
delirium |
| The impact of sepsis, delirium, and psychological distress on self-rated cognitive function in ICU survivors-a prospective cohort study. | Bruck, E. Schandl, A. Bottai, M. Sackey, P. | J Intensive Care | 2018 |
Anxiety |
| Falls and Delirium in an Acute Care Setting: A Retrospective Chart Review Before and After an Organization Wide Interprofessional Education. | Babine, R. L. Hyrkas, K. E. Hallen, S. Wierman, H. R. Bachand, D. A. Chapman, J. L. Fuller, V. J. | J Clin Nurs | 2018 |
delirium |
| Prognostic effects of delirium motor subtypes in hospitalized older adults: A prospective cohort study. | Avelino-Silva, T. J. Campora, F. Curiati, J. A. E. Jacob-Filho, W. | PLoS One | 2018 | |
| Recognition of Delirium Features in Clinical Practice: Data from the "Delirium Day 2015" National Survey. | Mossello, E. Tesi, F. Di Santo, S. G. Mazzone, A. Torrini, M. Cherubini, A. Bo, M. Musicco, M. Bianchetti, A. Ferrari, A. Ferrara, N. Trabucchi, M. Morandi, A. Bellelli, G. | J Am Geriatr Soc | 2017 |
arousal |
| A Pilot Analysis of the Association Between Types of Monitored Anesthesia Care Drugs and Outcomes in Transfemoral Aortic Valve Replacement Performed Without General Anesthesia. | Chen, E. Y. Sukumar, N. Dai, F. Akhtar, S. Schonberger, R. B. | Journal of Cardiothoracic and Vascular Anesthesia | 2017 |
age |
| Dexmedetomidine Based Sedation for Post-surgery Critically Ill Adults: A Meta-analysis of Randomized Controlled Trials. | Fan, H. Zhao, Y. Sun, M. Ye, J. H. Chen, G. D. Zhu, J. H. | Iran J Public Health | 2017 |
Delirium |
| Delirium and mental health history as predictors of aggression in individuals with dementia in inpatient settings. | Wharton T, Paulson D, Macri L, Dubin L | Aging & mental health | 2016 |
Mental Health |
| Development and Validation of an Abbreviated Questionnaire to Easily Measure Cognitive Failure in ICU Survivors: A Multicenter Study. | Wassenaar, Annelies De Reus, Jorn Donders, A. Rogier T. Schoonhoven, Lisette Cremer, Olaf L. De Lange, Dylan W. Van Dijk, Diederik Slooter, Arjen J. C. Pickkers, Peter Van Den Boogaard, Mark | Crit Care Med | 2018 |
Psychometrics — Statistics and Numerical Data |
| Practice Patterns and Outcomes Associated With Early Sedation Depth in Mechanically Ventilated Patients: A Systematic Review and Meta-Analysis. | Stephens, R. J. Dettmer, M. R. Roberts, B. W. Ablordeppey, E. Fowler, S. A. Kollef, M. H. Fuller, B. M. | Crit Care Med | 2017 | |
| Nursing assessment as an effective tool for the identification of delirium risk in older in-patients: a case-control study. | Solà-Miravete E, López C, Martínez-Segura E, Adell-Lleixà M, Juvé-Udina ME, Lleixà-Fortuño M | Journal of clinical nursing | 2017 |
delirium |
| Implementing ACOVE quality indicators as an intervention checklist to improve care for hospitalized older adults. | Sinvani, L. Kozikowski, A. Smilios, C. Patel, V. Qiu, G. Akerman, M. Lesser, M. Rosenberg, D. Wolf-Klein, G. Pekmezaris, R. | Journal of Hospital Medicine | 2017 |
indwelling catheter |
| Health and social factors associated with a delayed discharge amongst inpatients in acute geriatric wards: A retrospective observational study. | Moore, G. Hartley, P. Romero-Ortuno, R. | Geriatrics & Gerontology International | 2017 |
frail older adults |
| Impact of restarting home neuropsychiatric medications on sedation outcomes in medical intensive care unit patients | La, M. K. Thompson Bastin, M. L. Gisewhite, J. T. Johnson, C. A. Flannery, A. H. | Journal of Critical Care | 2018 |
amfebutamone |
| Exposure to anticholinergic and sedative medicines as indicators of high-risk prescriptions in the elderly. | Jean-Bart, E. Moutet, C. Dauphinot, V. Krolak-Salmon, P. Mouchoux, C. | International Journal of Clinical Pharmacy | 2017 |
NCT01483456 |
| Delirium in hemodialysis predicts mortality: a single-center, long-term observational study. | Yasui-Furukori, N. Tarakita, N. Uematsu, W. Saito, H. Nakamura, K. Ohyama, C. Sugawara, N. | Neuropsychiatr Dis Treat | 2017 |
delirium |
| The prevention of delirium in elderly with obstructive sleep apnea (PODESA) study: protocol for a multi-centre prospective randomized, controlled trial. | Wong, Jean Lam, David Choi, Stephen Singh, Mandeep Siddiqui, Naveed Sockalingam, Sanjeev Chung, Frances | BMC Anesthesiology | 2018 |
Delirium — Prevention and Control — In Old Age |
| Using simulated family presence to decrease agitation in older hospitalized delirious patients: A randomized controlled trial. | Waszynski, Christine M. Milner, Kerry A. Staff, Ilene Molony, Sheila L. | International Journal of Nursing Studies | 2018 |
Dementia |
| DemDel, a nursing-led practice-based delirium intervention, improves certain outcomes for older cognitively impaired inpatients. | Wand, A. P. Teodorczuk, A. | Evidence-based nursing | 2017 |
delirium |
| Delirium Severity Post-Surgery and its Relationship with Long-Term Cognitive Decline in a Cohort of Patients without Dementia. | Vasunilashorn, S. M. Fong, T. G. Albuquerque, A. Marcantonio, E. R. Schmitt, E. M. Tommet, D. Gou, Y. Travison, T. G. Jones, R. N. Inouye, S. K. | Journal of Alzheimer's Disease | 2017 |
aged |
| Turning education into action: Impact of a collective social education approach to improve nurses' ability to recognize and accurately assess delirium in hospitalized older patients. | Travers, C. Henderson, A. Graham, F. Beattie, E. | Nurse Educ Today | 2017 |
Delirium |
| Reduced level of arousal and increased mortality in adult acute medical admissions: a systematic review and meta-analysis. | Todd, A. Blackley, S. Burton, J. K. Stott, D. J. Ely, E. W. Tieges, Z. MacLullich, A. M. J. Shenkin, S. D. | BMC Geriatr | 2017 |
Altered mental status |
| Risk factors and outcomes of critically ill patients with acute brain failure: A novel end point. | Singh, T. D. O'Horo, J. C. Gajic, O. Sakusic, A. Day, C. N. Mandrekar, J. Kashyap, R. Reddy, D. R. S. Rabinstein, A. A. | Journal of Critical Care | 2018 |
acute brain failure |
| Intraoperative oxygen concentration and neurocognition after cardiac surgery: study protocol for a randomized controlled trial. | Shaefi, S. Marcantonio, E. R. Mueller, A. Banner-Goodspeed, V. Robson, S. C. Spear, K. Otterbein, L. E. O'Gara, B. P. Talmor, D. S. Subramaniam, B. | Trials | 2017 |
Cardiac surgery |
| A novel scoring system to predict delirium and its relationship with the clinical course in patients with acute decompensated heart failure. | Sakaguchi, T. Watanabe, M. Kawasaki, C. Kuroda, I. Abe, H. Date, M. Ueda, Y. Yasumura, Y. Koretsune, Y. | J Cardiol | 2017 |
Acute heart failure |