Delirium Bibliography

Delirium Bibliography books graphicWhat is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!

How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.

Reference Information

Title
Risk factors for postoperative delirium in frail elderly patients undergoing on-pump cardiac surgery and development of a prediction model-a prospective observational study
Authors
Ding, Y. Gao, J. Ge, Y. Huang, T. Zhang, Y.
Year
2024
Journal
Front Cardiovasc Med
Abstract

BACKGROUND: To identify the risk factors for postoperative delirium (POD) after cardiac surgery in frail elderly patients and develop a receiver operating characteristic (ROC) prediction model to confirm the effectiveness. METHODS: This was a prospective observational study, patients were assessed preoperatively according to the frailty index (FI) scale. Cerebral (SctO(2)) was assessed at different time points using near-infrared spectroscopy (NIRS). On the basis of the occurrence of POD within 7 days after surgery, patients were divided into POD and non-POD groups. Risk factors were analyzed using logistic regression analysis, while their predictive values were evaluated using the receiver operating characteristic curve analysis. RESULTS: POD was significantly associated with frailty, lower preoperative MMSE scores, hyperlipidemia, diabetes, cerebrovascular disease, lower hemoglobin level, lower albumin level, longer operation time, longer CPB time, lower SctO(2) at T5, and lower SctO(2baseline) (P < 0.05). SrtO(2) and SmtO(2) did not differ significantly between groups. FI, preoperative MMSE score, and operation time as independent risk factors (P < 0.05). Significant predictive value was demonstrated in all 3 variables (P < 0.001; respectively). Among them, high sensitivity and specificity were observed with the FI (cut-off value 0.27, sensitivity 75%, specificity 73.5%) and operation time (cut-off value 237.5, sensitivity 62.5%, specificity 78.6%). CONCLUSIONS: The FI, preoperative MMSE score, and operation time were independent risk factors for POD in elderly patients after cardiac surgery, with high predictive value observed with the FI and operation time. Cerebral oxygen saturation was associated with POD but was not an independent risk factor. CLINICAL TRIAL REGISTRATION: Chinese Clinical Trail Registry, No: chictr2200056038.

PMID

PMID: 39171326

PMCID: PMC11335481

Keywords

cardiac surgery
cardiopulmonary bypass
frailty
near-infrared spectroscopy
postoperative delirium
tissue oxygen saturation

Page(s)
Issue

Search:
Total Records Found: 6347, showing 100 per page
TitleAuthorsJournalYearKeywords
The Hospital Elder Life Program: Past and Future. Scheunemann, L. P. Girard, T. D. Skidmore, E. R. Resnick, N. M. Am J Geriatr Psychiatry 2018
Delirium in the Acute Phase of Ischemic Stroke: Incidence, Risk Factors, and Effects on Functional Outcome. Qu, J. Chen, Y. Luo, G. Zhong, H. Xiao, W. Yin, H. J Stroke Cerebrovasc Dis 2018

Activities of Daily Living
Aged
Brain Ischemia/diagnosis/*epidemiology/physiopathology/psychology
China/epidemiology
Delirium/diagnosis/*epidemiology/physiopathology/psychology
Diffusion Magnetic Resonance Imaging
Disability Evaluation
Female
Health Status
Humans
Incidence
Male
Middle Aged
Neuropsychological Tests
Prognosis
Prospective Studies
Recovery of Function
Risk Factors
Severity of Illness Index
Stroke/diagnosis/*epidemiology/physiopathology/psychology
Time Factors
Delirium
Mri
functional status
ischemic stroke
psychiatric symptoms

Effect of dynamic light at the coronary care unit on the length of hospital stay and development of delirium: A retrospective cohort study. Pustjens, T. Schoutens, A. M. C. Janssen, L. Heesen, W. F. Journal of Geriatric Cardiology 2018

neuroleptic agent
tranquilizer
adult
age
aged
article
cardiac patient
circadian rhythm
clinical effectiveness
clinical outcome
cohort analysis
consultation
controlled study
coronary care unit
delirium
evaluation study
female
fluorescent lighting
geriatric care
geriatrician
hospitalization
human
illumination
incidence
length of stay
major clinical study
male
observational study
outcome assessment
phototherapy
prescription
retrospective study
risk factor
risk reduction

Frailty and Delirium in Older Adults: A Systematic Review and Meta-Analysis of the Literature. Persico, I. Cesari, M. Morandi, A. Haas, J. Mazzola, P. Zambon, A. Annoni, G. Bellelli, G. J Am Geriatr Soc 2018

cognition
delirium
frailty
geriatric assessment
review

Medications and Patient Characteristics Associated With Falling in the Hospital. OʼNeil, C. A. Krauss, M. J. Bettale, J. Kessels, A. Costantinou, E. Dunagan, W. C. Fraser, V. J. Journal of Patient Safety 2018

adult
article
case control study
clinical evaluation
controlled study
dizziness
fall risk
female
human
incontinence
major clinical study
muscle
obesity
randomized controlled trial
risk assessment
risk factor
tertiary care center
underweight
anticonvulsive agent
haloperidol
insulin
proton pump inhibitor
tricyclic antidepressant agent

Delirium detection using relative delta power based on 1-minute single-channel EEG: a multicentre study. Numan, T. van den Boogaard, M. Kamper, A. M. Rood, P. J. T. Peelen, L. M. Slooter, A. J. C. Br J Anaesth 2018

complications, postoperative
delirium
electroencephalography
intensive care unit
monitoring
postoperative care

Low skeletal muscle mass as a risk factor for postoperative delirium in elderly patients undergoing colorectal cancer surgery. Mosk, C. A. L. A. van Vugt J de Jonge, H. Witjes, C. D. Buettner, S. Ijzermans, J. N. van der Laan, L. Clin Interv Aging 2018

Aged
Aged, 80 and over
Cohort Studies
Colorectal Neoplasms/*surgery
Correlation of Data
Delirium/epidemiology/*etiology
Disability Evaluation
Female
Humans
Male
*Muscle Strength
Netherlands
Postoperative Complications/*etiology
Protein-Energy Malnutrition/complications/epidemiology
Retrospective Studies
Risk Factors
Sarcopenia/*complications/epidemiology
*colorectal surgery
*elderly
*nomogram
*postoperative delirium
*sarcopenia
*skeletal muscle mass

Symptom expression in advanced cancer patients admitted to hospice or home care with and without delirium. Mercadante, S. Masedu, F. Maltoni, M. De Giovanni, D. Montanari, L. Pittureri, C. Berte, R. Russo, D. Ursini, L. Marinangeli, F. Aielli, F. Intern Emerg Med 2018

Advanced cancer
Delirium
Edmonton Symptom Assessment Scale
Memorial Delirium Assessment Scale
Palliative care

Symptom Expression in Patients with Advanced Cancer Admitted to an Acute Supportive/Palliative Care Unit With and Without Delirium. Mercadante, S. Adile, C. Ferrera, P. Cortegiani, A. Casuccio, A. Oncologist 2018

Advanced cancer
Delirium
Edmonton Symptom Assessment Scale
Memorial Delirium Assessment Scale
Palliative care
article.

Pain, agitation and delirium assessment and management in a community medical-surgical ICU: results from a prospective observational study and nurse survey. Maximous, R. Miller, F. Tan, C. Camargo, M. Ross, K. Marshall, C. Yung, P. Fleming, D. Law, M. Tsang, J. L. Y. BMJ Open Qual 2018

attitudes
critical care
nurses
performance measures

Evaluating the risk profile of quetiapine in treating delirium in the intensive care adult population: A retrospective review. Mangan, K. C. McKinzie, B. P. Deloney, L. P. Leon, S. M. Eriksson, E. A. J Crit Care 2018

Delirium
QTc prolongation
Quetiapine

Cerebral monitoring of anaesthesia on reducing cognitive dysfunction and postoperative delirium: a systematic review. Luo, C. Zou, W. J Int Med Res 2018

Anesthesia/*adverse effects/methods
Cognitive Dysfunction/etiology/*prevention & control
Delirium/etiology/*prevention & control
Electroencephalography
Humans
*Intraoperative Neurophysiological Monitoring/methods
Postoperative Complications/etiology/prevention & control
Randomized Controlled Trials as Topic
Cerebral monitoring
anaesthesia
cognitive dysfunction
meta-analysis
postoperative delirium
systematic review

Dysfunctional cerebral autoregulation is associated with delirium in critically ill adults. Lee, K. F. Wood, M. D. Maslove, D. M. Muscedere, J. G. Boyd, J. G. J Cereb Blood Flow Metab 2018

Cerebral autoregulation
cerebral oximetry
critical illness
delirium
near-infrared spectroscopy

Defining delirium in idiopathic Parkinson's disease: A systematic review. Lawson, R. A. McDonald, C. Burn, D. J. Parkinsonism and Related Disorders 2018

adult
adverse outcome
article
delirium
diagnosis
female
hospital patient
hospitalization
human
male
motor dysfunction
Parkinson disease
prevalence
prospective study
risk factor
systematic review

Delirium assessment in neuro-critically ill patients: A validation study. Larsen, L. K. Frokjaer, V. G. Nielsen, J. S. Skrobik, Y. Winkler, Y. Moller, K. Petersen, M. Egerod, I. Acta Anaesthesiol Scand 2018

acute brain injury
confusion assessment method for the ICU
delirium
intensive care delirium screening checklist
international classification of diseases-10
neurointensive care unit

Benzodiazepine Use and Neuropsychiatric Outcomes in the ICU: A Systematic Review Kok, L. Slooter, A. J. Hillegers, M. H. van Dijk, D. Veldhuijzen, D. S. Crit Care Med 2018
Hospital Elder Life Program: Systematic Review and Meta-analysis of Effectiveness Hshieh, T. T. Yang, T. Gartaganis, S. L. Yue, J. Inouye, S. K. Am J Geriatr Psychiatry 2018

Delirium prevention
Hospital Elder Life Program
multicomponent nonpharmacological intervention

Predictive Modeling for Geriatric Hip Fracture Patients: Early Surgery and Delirium Have the Largest Influence on Length of Stay. Hecht, G. Slee, C. A. Goodell, P. B. Taylor, S. L. Wolinsky, P. R. J Am Acad Orthop Surg 2018
The Erasmus Frailty Score is associated with delirium and 1-year mortality after Transcatheter Aortic Valve Implantation in older patients. The TAVI Care & Cure program. Goudzwaard, J. A. de Ronde-Tillmans, Mjag El Faquir, N. Acar, F. Van Mieghem, N. M. Lenzen, M. J. de Jaegere, P. P. T. Mattace-Raso, F. U. S. Int J Cardiol 2019

Delirium
Erasmus Frailty Score
Frailty
Mortality
Prognosis
Transcatheter Aortic Valve Implantation

Transcutaneous electrical acupoint stimulation for prevention of postoperative delirium in geriatric patients with silent lacunar infarction: a preliminary study. Gao, F. Zhang, Q. Li, Y. Tai, Y. Xin, X. Wang, X. Wang, Q. Clin Interv Aging 2018

*Acupuncture Points
Aged
Blood-Brain Barrier/physiology
Delirium/physiopathology/*prevention & control
Female
Finland
Humans
Inflammation Mediators/blood
Male
Middle Aged
Neurologic Examination
Postoperative Complications/physiopathology/*prevention & control
Preoperative Care
Risk Factors
Stroke, Lacunar/*complications/physiopathology
Transcutaneous Electric Nerve Stimulation/*methods
blood-brain barrier
delirium
geriatric
lacunar infarction
neuroinflammation
transcutaneous electrical acupoint stimulation

Dexmedetomidine in prevention and treatment of postoperative and intensive care unit delirium: a systematic review and meta-analysis. Flükiger, J. Hollinger, A. Speich, B. Meier, V. Tontsch, J. Zehnder, T. Siegemund, M. Annals of Intensive Care 2018

dexmedetomidine
haloperidol
midazolam
placebo
article
bradycardia
clinical outcome
Cochrane Library
drug use
human
hypertension
hypotension
Medline
meta analysis
mortality
postoperative delirium
priority journal
randomized controlled trial (topic)
systematic review

Long-term prognostic value of delirium in elderly patients with acute cardiac diseases admitted to two cardiac intensive care units: a prospective study (DELIRIUM CORDIS). Falsini, G. Grotti, S. Porto, I. Toccafondi, G. Fraticelli, A. Angioli, P. Ducci, K. Liistro, F. Pieroni, M. Taddei, T. Romanelli, S. Rossi, R. Bolognese, L. Eur Heart J Acute Cardiovasc Care 2018

Acute Disease
Aged
Aged, 80 and over
Delirium/epidemiology/*etiology
Female
Heart Diseases/*complications/mortality
Humans
Incidence
Intensive Care Units/*statistics & numerical data
Italy/epidemiology
Length of Stay/trends
Male
Prevalence
Prognosis
Prospective Studies
*Risk Assessment
Risk Factors
Survival Rate/trends
Delirium
cardiac intensive care unit
confusion assessment method
elderly
mortality

Persistent Delirium in Elderly patients Three Months After Hospital Discharge from a University Clinic. Constaín, G. A. Ocampo Saldarriaga, M. V. Velásquez Tirado, J. D. Rodríguez-Gázquez, M. D. L. Á Betancur Morales, L. M. Rico Escobar, J. J. Castilla Agudelo, G. A. Maya Osorno, A. F. Revista Colombiana de Psiquiatria 2018

aged
article
clinical article
delirium
descriptive research
DSM-5
follow up
hospital discharge
hospitalization
human
longitudinal study
persistent delirium
prevalence

A Web-Based Serious Game on Delirium as an Educational Intervention for Medical Students: Randomized Controlled Trial. Buijs-Spanjers, K. R. Hegge, H. H. Jansen, C. J. Hoogendoorn, E. de Rooij, S. E. JMIR Serious Games 2018

delirium
education
medical students
serious game

Relationship Between Near-Infrared Spectroscopy-Derived Cerebral Oxygenation and Delirium in Critically Ill Patients: A Systematic Review. Bendahan, N. Neal, O. Ross-White, A. Muscedere, J. Boyd, J. G. J Intensive Care Med 2018

Cam-icu
cerebral oxygenation
critical illness
delirium
intensive care unit
near-infrared spectroscopy

Ability of suvorexant to prevent delirium in patients in the intensive care unit: a randomized controlled trial. Azuma, K. Takaesu, Y. Soeda, H. Iguchi, A. Uchida, K. Ohta, S. Mishima, S. Inoue, T. Inoue, Y. Oda, J. Acute Med Surg 2018

Delirium
intensive care unit
prevention
suvorexant

Incidence of postoperative delirium in elderly ambulatory patients: A prospective evaluation using the FAM-CAM instrument. Aya, A. G. M. Pouchain, P. H. Thomas, H. Ripart, J. Cuvillon, P. J Clin Anesth 2018

Ambulatory surgery
Elderly
Fam-cam
Postoperative delirium

Potential Role of Exogenous Melatonin Supplement in Delirium Prevention in Critically Ill Patients: A Double-Blind Randomized Pilot Study. Abbasi, S. Farsaei, S. Ghasemi, D. Mansourian, M. Iran J Pharm Res 2018

Clinical trial
Critical care
Delirium
Melatonin

Predictive nomogram for postoperative delirium in elderly patients with a hip fracture. Zhang, X. Tong, D. K. Ji, F. Duan, X. Z. Liu, P. Z. Qin, S. Xu, K. H. Di-li, X. T. Injury 2018

aged
article
calibration
cognitive defect
comorbidity
controlled study
erythrocyte
female
femoral neck fracture
human
human cell
intensive care
major clinical study
male
nomogram
postoperative delirium
prevention
probability
retrospective study
risk assessment
risk factor
surgery

Advances in dementia with Lewy bodies Armstrong, M. J. Ther Adv Neurol Disord 2021

Lewy body dementia
Lewy body disease [MeSH]
dementia with Lewy bodies

Factors Influencing CAM-ICU Documentation and Inappropriate "Unable to Assess" Responses Awan, O. M. Buhr, R. G. Kamdar, B. B. Am J Crit Care 2021

Aged, 80 and over
*Delirium/diagnosis
Documentation
Humans
Intensive Care Units
*Nursing Care
Restraint, Physical

Prediction of Postictal Delirium Following Status Epilepticus in the ICU: First Insights of an Observational Cohort Study Baumann, S. M. Semmlack, S. Hunziker, S. Kaplan, P. W. De Marchis, G. M. Rüegg, S. Marsch, S. Sutter, R. Crit Care Med 2021

Aged
Benzodiazepines/administration & dosage
Cohort Studies
Delirium/*diagnosis/epidemiology
Female
Humans
Intensive Care Units/organization & administration/statistics & numerical data
Male
Mass Screening/methods/statistics & numerical data
Middle Aged
Proportional Hazards Models
Retrospective Studies
Risk Factors
Seizures/complications/epidemiology
Severity of Illness Index

Dementia as a predictor of morbidity and mortality in patients with delirium. van Roessel, S. Keijsers, C. J. P. W. Romijn, M. D. M. Maturitas 2019

advance care planning
Barthel index
caregiver
cognition
daily life activity
delirium
dementia
deterioration
functional status
hospital patient
human
Mini Mental State Examination
morbidity
mortality
mortality rate
review
risk factor

Factors Associated With Delirium Following Electroconvulsive Therapy: A Systematic Review. Tsujii, T. Uchida, T. Suzuki, T. Mimura, M. Hirano, J. Uchida, H. J Ect 2019
Predictors of delirium after cardiac surgery in patients with sleep-disordered breathing. Tafelmeier, M. Knapp, M. Lebek, S. Floerchinger, B. Camboni, D. Creutzenberg, M. Wittmann, S. Zeman, F. Schmid, C. Maier, L. S. Wagner, S. Arzt, M. Eur Respir J 2019
The trajectory of C-reactive protein serum levels in older hip fracture patients with postoperative delirium. Slor, C. J. Witlox, J. Adamis, D. Jansen, Rwmm Houdijk, A. P. J. van Gool, W. A. de Jonghe, J. F. M. Eikelenboom, P. Int J Geriatr Psychiatry 2019

C-reactive protein
hip surgery
inflammation
postoperative delirium

Risk Factors for Postoperative Delirium in Type A Aortic Dissection Patients: A Retrospective Study. Shi, Q. Mu, X. Zhang, C. Wang, S. Hong, L. Chen, X. Med Sci Monit 2019
Cortical and subcortical changes in resting-state functional connectivity before and during an episode of postoperative delirium. Oh, J. Shin, J. E. Yang, K. H. Kyeong, S. Lee, W. S. Chung, T. S. Kim, J. J. Aust N Z J Pschiatry 2019

Postoperative delirium
central executive network
default mode network
resting-state functional connectivity
salience network
subcortical abnormality

Association of COMT Val(158)Met Polymorphism With Delirium Risk and Outcomes After Traumatic Brain Injury. Nekrosius, D. Kaminskaite, M. Jokubka, R. Pranckeviciene, A. Lideikis, K. Tamasauskas, A. Bunevicius, A. J Neuropsychiatry Clin Neurosci 2019

Delirium
Traumatic Brain Injury

Association of earlier extubation and postoperative delirium after coronary artery bypass grafting. Muller Moran, H. R. Maguire, D. Maguire, D. Kowalski, S. Jacobsohn, E. Mackenzie, S. Grocott, H. Arora, R. C. Journal of Thoracic and Cardiovascular Surgery 2019

adult
adverse event
anesthesia
article
artificial ventilation
comorbidity
controlled study
coronary artery bypass graft
extubation
female
human
major clinical study
male
perioperative period
postoperative delirium
preoperative evaluation
retrospective study
surgery

Delirium, Dementia, and In-Hospital Mortality: The Results From the Italian Delirium Day 2016, A National Multicenter Study. Morandi, A. Di Santo, S. G. Zambon, A. Mazzone, A. Cherubini, A. Mossello, E. Bo, M. Marengoni, A. Bianchetti, A. Cappa, S. Fimognari, F. Antonelli Incalzi, R. Gareri, P. Perticone, F. Campanini, M. Penco, I. Montorsi, M. Di Bari, M. Trabucchi, M. Bellell J Gerontol A Biol Sci Med Sci 2019

Acute hospital
Cognitive impairment
Confusion
Outcomes

Type D personality is a predictor of prolonged acute brain dysfunction (delirium/coma) after cardiovascular surgery. Matsuishi, Y. Shimojo, N. Unoki, T. Sakuramoto, H. Tokunaga, C. Yoshino, Y. Hoshino, H. Ouchi, A. Kawano, S. Sakamoto, H. Hiramatsu, Y. Inoue, Y. BMC Psychol 2019

Aged
Brain/physiopathology
Cardiac Surgical Procedures/*psychology
Cohort Studies
Coma/*etiology
Delirium/diagnosis/*etiology
Depression/diagnosis/etiology
Female
Humans
Japan
Male
Middle Aged
Personality
Pilot Projects
Prevalence
*Type D Personality
Critical care
Delirium
Delirium/coma days
Depression
Intensive care units
Thoracic surgery
Type D personality

Delirium after primary percutaneous coronary intervention in aged individuals with acute ST-segment elevation myocardial infarction: A retrospective study. Li, S. Zhang, X. H. Zhou, G. D. Wang, J. F. Exp Ther Med 2019

ST-segment elevation
delirium
incidence
myocardial infarction
percutaneous coronary intervention
risk factors

Preventing Delirium Takes a Village: Systematic Review and Meta-Analysis of Delirium Preventive Models of Care. Khan, A. Boukrina, O. Oh-Park, M. Flanagan, N. A. Singh, M. Oldham, M. J Hosp Med 2019
Clinical predictors of postoperative delirium, functional status, and mortality in geriatric patients undergoing non-elective surgery for hip fracture. Harris, M. J. Brovman, E. Y. Urman, R. D. J Clin Anesth 2019

Delirium
Dementia
Functional status
Geriatric
Hip fracture
Mortality
Outcomes

Impairments in balance and mobility identify delirium in patients with comorbid dementia. Gual, N. Richardson, S. J. Davis, D. H. J. Bellelli, G. Hasemann, W. Meagher, D. Kreisel, S. H. MacLullich, A. M. J. Cerejeira, J. Inzitari, M. Morandi, A. Int Psychogeriatr 2019

Delirium
Dementia
Diagnosis and Classification
Motor Disorders

Delirium motor subtypes and prognosis in hospitalized geriatric patients - A prospective observational study. Evensen, S. Saltvedt, I. Lydersen, S. Wyller, T. B. Taraldsen, K. Sletvold, O. J Psychosom Res 2019

Dmss
Delirium
Geriatric
Motor subtypes

Delirium risk in non-surgical patients: systematic review of predictive tools. Dylan, F. Byrne, G. Mudge, A. M. Arch Gerontol Geriatr 2019

clinical prediction rule
delirium
systematic review

Pain, Opioid Intake, and Delirium Symptoms in Adults Following Joint Replacement Surgery. Denny, D. L. Lindseth, G. N. West J Nurs Res 2019

joint replacement surgery
older adults
postoperative pain
subsyndromal delirium

Addition of Vitamin B Complex to Prime Solution in Cobalamin-Deficient Patients to Prevent Postoperative Delirium. Demirdas, E. Atilgan, K. The Heart Surgery Forum 2019

vitamin B complex
aged
cardiopulmonary bypass
controlled clinical trial
controlled study
B12 deficiency
delirium
female
human
male
middle aged
postoperative complication
retrospective study
solution and solubility

Postoperative Delirium and Postoperative Cognitive Dysfunction: Overlap and Divergence Daiello, L. A. Racine, A. M. Yun Gou, R. Marcantonio, E. R. Xie, Z. Kunze, L. J. Vlassakov, K. V. Inouye, S. K. Jones, R. N. Alsop, D. Travison, T. Arnold, S. Cooper, Z. Dickerson, B. Fong, T. Metzger, E. Pascual-Leone, A. Schmitt, E. M. Shafi, M. Cavalla Anesthesiology 2019
CSF Beta-amyloid 1-42 Concentration Predicts Delirium Following Elective Arthroplasty Surgery in an Observational Cohort Study. Cunningham, E. L. McGuinness, B. McAuley, D. F. Toombs, J. Mawhinney, T. O'Brien, S. Beverland, D. Schott, J. M. Lunn, M. P. Zetterberg, H. Passmore, A. P. Ann Surg 2018

adverse outcome
age
aged
Alzheimer disease
article
cerebrospinal fluid
cohort analysis
comorbidity
controlled study
drug therapy
female
hip
human
incidence
knee arthroplasty
major clinical study
male
outcome assessment
postoperative delirium
preoperative evaluation
risk factor
spinal anesthesia
surgery
amyloid beta protein
amyloid beta protein[1-42]
apolipoprotein E
endogenous compound
opiate

Three Nurse-administered Protocols Reduce Nutritional Decline and Frailty in Older Gastrointestinal Surgery Patients: A Cluster Randomized Trial. Chia-Hui Chen, C. Yang, Y. T. Lai, I. R. Lin, B. R. Yang, C. Y. Huang, J. Tien, Y. W. Chen, C. N. Lin, M. T. Liang, J. T. Li, H. C. Huang, G. H. Inouye, S. K. J Am Med Dir Assoc 2019

Frailty
Hospital Elder Life Program
Ileus
nutritional status
surgery

Moderate hypercapnia may not contribute to postoperative delirium in patients undergoing bronchoscopic intervention. Cheng, Q. Li, L. Yang, M. Sun, L. Li, R. Huang, R. Ma, J. Medicine 2019

Age Factors
Aged
Anesthesia, General/*adverse effects
Bronchoscopy/*adverse effects
Deep Sedation/*adverse effects
Delirium/*etiology
Female
Humans
Hypercapnia/*complications
Male
Middle Aged
Multivariate Analysis
Operative Time
Postoperative Complications/*etiology/psychology
Risk Factors

Evaluation of a method to estimate the point prevalence of cognitive impairment and delirium in a multi-campus Australian health service. Casey, P. Darzins, P. Webb-St Mart, M. Baldwin, C. Riddell, K. Johnson, C. Cross, W. Australas J Ageing 2019

adult
cognitive impairment
delirium
prevalence

Effect of Targeting Mean Arterial Pressure During Cardiopulmonary Bypass by Monitoring Cerebral Autoregulation on Postsurgical Delirium Among Older Patients: A Nested Randomized Clinical Trial. Brown, C. H. th Neufeld, K. J. Tian, J. Probert, J. LaFlam, A. Max, L. Hori, D. Nomura, Y. Mandal, K. Brady, K. Hogue, C. W. Shah, A. Zehr, K. Cameron, D. Conte, J. Bienvenu, O. J. Gottesman, R. Yamaguchi, A. Kraut, M. JAMA Surg 2019
A Comparison of Resource Utilization in the Management of Anticholinergic Delirium Between Physostigmine and Nonantidote Therapy. Boley, S. P. Stellpflug, S. J. Annals of Pharmacotherapy 2019

adult
adverse event
article
bradycardia
clinical decision making
clinical pharmacology
controlled study
delirium
drug therapy
female
gender
human
institutional review
intensive care unit
intubation
major clinical study
male
medical record review
resource allocation
retrospective study
seizure
toxicology
vomiting
cholinergic receptor blocking agent
physostigmine

Do health care professionals worry about delirium? Relatives' experience of delirium in the intensive care unit: A qualitative interview study. Bohart, S. Merete Moller, A. Forsyth Herling, S. Intensive Crit Care Nurs 2019

Delirium
Family
Intensive care units
Interview
Qualitative research
Relatives

The association of indwelling urinary catheter with delirium in hospitalized patients and nursing home residents: an explorative analysis from the “Delirium Day 2015”. Bo, M. Porrino, P. Di Santo, S. G. Mazzone, A. Cherubini, A. Mossello, E. Bianchetti, A. Musicco, M. Ferrari, A. Ferrara, N. Filippini, C. Trabucchi, M. Morandi, A. Bellelli, G. Aging Clinical and Experimental Research 2019

indwelling urinary catheter
aged
aged hospital patient
article
cognitive defect
daily life activity
delirium
female
functional status assessment
geriatric assessment
health status
human
major clinical study
male
multicenter study
multivariate logistic regression analysis
nursing home patient
nutritional assessment
prevalence

Assessment of analgesia, sedation, physical restraint and delirium in patients admitted to Spanish intensive care units. Proyecto ASCyD. Arias-Rivera, S. López-López, C. Frade-Mera, M. J. Via-Clavero, G. Rodríguez-Mondéjar, J. J. Sánchez-Sánchez, M. M. Acevedo-Nuevo, M. Gil-Castillejos, D. Robleda, G. Cachón-Pérez, M. Latorre-Marco, I. Enfermeria intensiva 2019

NCT03773874
adult
agitation
analgesia
article
delirium
female
human
intensive care unit
major clinical study
male
multicenter study
nursing assessment
prevalence
prospective study
sedation

Influence of early elective tracheostomy on the incidence of postoperative complications in patients undergoing head and neck surgery. Meier, J. Wunschel, M. Angermann, A. Ettl, T. Metterlein, T. Klingelhöffer, C. Reichert, T. E. Ritzka, M. BMC Anesthesiology 2019

endotracheal tube
adult
aged
article
artificial ventilation
clinical article
controlled study
elective surgery
endotracheal intubation
female
head and neck surgery
hospitalization
human
incidence
intensive care unit
male
medical record review
microsurgery
morbidity
mortality rate
oropharynx tumor
patient transport
pneumonia
postoperative delirium
risk benefit analysis
surgical risk
tissue graft
tracheostomy
treatment duration
very elderly

Pharmacological Prevention of Postoperative Delirium: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Liu, Y. Li, X. J. Liang, Y. Kang, Y. Evidence-Based Complementary and Alternative Medicine 2019

cyproheptadine
dexamethasone
dexmedetomidine
donepezil
gabapentin
haloperidol
hypertonic solution
ketamine
melatonin
methylprednisolone
nimodipine
olanzapine
ondansetron
pregabalin
risperidone
rivastigmine
yokukansan
tryptophan
bradykinesia
clinical outcome
drug efficacy
human
hypertension
incidence
meta analysis
mortality
postoperative delirium
randomized controlled trial (topic)
review
risk reduction
systematic review
tachycardia
therapy effect
tj 54

Delirium: Medical Students’ Knowledge and Effectiveness of Different Teaching Methods. Baessler, F. Ciprianidis, A. Rizvi, A. Z. Weidlich, J. Wagner, F. L. Klein, S. B. Baumann, T. C. Nikendei, C. Schultz, J. H. Am J Geriatr Psychiatry 2019

adult
analysis of covariance
article
controlled study
curriculum
delirium
female
gender
Germany
human
learning
male
medical education
medical school
medical student
multiple choice test
post hoc analysis
questionnaire
randomized controlled trial
recall
self evaluation
software
videorecording

Low Plasma Cholinesterase Activity is Associated With Postoperative Delirium After Noncardiac Surgery in Elderly Patients: AProspective Observational Study. Zhao, B. Ni, Y. Tian, X. Psychosomatics 2019

acetylcholinesterase
cholinesterase
aged
alcohol consumption
APACHE
article
blood sampling
cervical spine
cholinesterase blood level
cognition
cohort analysis
comparative study
consciousness level
controlled study
enzyme activity
female
gastrectomy
Han Chinese
human
incidence
laminectomy
major clinical study
male
observational study
postoperative delirium
postoperative period
prospective study
subtotal gastrectomy
surgical approach
surgical intensive care unit
total hip replacement
total knee arthroplasty

Interventions for preventing delirium in older people in institutional long-term care. Clegg A, Siddiqi N, Heaven A, Young J, Holt R The Cochrane database of systematic reviews 2014

Aged, Delirium, chemically induced, Fluid Therapy, Frail Elderly, Humans, Institutionalization, Long-Term Care, Medication Reconciliation, Randomized Controlled Trials as Topic

Effect of flurbiprofen axetil on postoperative delirium for elderly patients. Wang, X. Wang, Y. Hu, Y. Wang, L. Zhao, W. Wei, L. Chen, H. Han, F. Brain Behav 2019

elder
flurbiprofen axetil
patient-controlled analgesia
postoperative delirium

Clinical and prognostic implications of delirium in elderly patients with non–ST-segment elevation acute coronary syndromes. Vives-Borrás, M. Martínez-Sellés, M. Ariza-Solé, A. Vidán, M. T. Formiga, F. Bueno, H. Sanchís, J. Alegre, O. Durán-Cambra, A. López-Palop, R. Abu-Assi, E. Sionis, A. Journal of Geriatric Cardiology 2019

aged
article
bleeding
cognitive defect
confounding variable
controlled study
female
hospital infection
hospitalization
human
incidence
major clinical study
male
mortality
multicenter study
non st segment elevation acute coronary syndrome
nursing home
prognosis
propensity score
prospective study
risk factor
very elderly
diuretic agent

Brain network disintegration as a final common pathway for delirium: a systematic review and qualitative meta-analysis. van Montfort, S. J. T. van Dellen, E. Stam, C. J. Ahmad, A. H. Mentink, L. J. Kraan, C. W. Zalesky, A. Slooter, A. J. C. Neuroimage Clin 2019

Aging
Brain
Cognitive impairment
Connectome
Delirium
Networks

Predictive Factors of Postoperative Delirium in Patients After Pancreaticoduodenectomy. Tomimaru, Y. Park, S. A. Shibata, A. Miyagawa, S. Noguchi, K. Noura, S. Imamura, H. Shirakawa, T. Dono, K. J Gastrointest Surg 2019

Delirium
Pancreaticoduodenectomy
Postoperative delirium

Bach to the Basics: Implementation and Impact of a Postoperative, Inpatient Personalized Music Program for Older Adults. Sharda, N. Mattoon, E. Matters, L. Prewitt, J. McDonald, S. Sloane, R. Cassas, C. White, H. J Perianesth Nurs 2019

delirium prevention
geriatric
music implementation
perioperative

Screening for delirium after surgery: validation of the 4 A's test (4AT) in the post-anaesthesia care unit. Saller, T. MacLullich, A. M. J. Schafer, S. T. Crispin, A. Neitzert, R. Schule, C. von Dossow, V. Hofmann-Kiefer, K. F. Anaesthesia 2019

delirium
post-anaesthesia care unit
postoperative complications

Measuring the distress related to delirium in older surgical patients and their relatives. Partridge, J. S. L. Crichton, S. Biswell, E. Harari, D. Martin, F. C. Dhesi, J. K. Int J Geriatr Psychiatry 2019

carer and relative distress
distress thermometer
older people
postoperative delirium
psychological and emotional distress

Functional Outcomes After Hip Fracture in Independent Community-Dwelling Patients. Ouellet, J. A. Ouellet, G. M. Romegialli, A. M. Hirsch, M. Berardi, L. Ramsey, C. M. Cooney, L. M., Jr. Walke, L. M. Journal of Hospital Medicine 2019

adult
article
delirium
drug therapy
human
neuroleptic agent

Clinical characteristics and prognosis for delirium in Spanish internal medicine departments: An analysis from a large clinical-administrative database. Marco, J. Mendez, M. Cruz-Jentoft, A. J. Garcia Klepzig, J. L. Calvo, E. Canora, J. Zapatero, A. Barba, R. Rev Clin Esp 2019

Anciano
Big data
Big data.
Delirio
Delirium
Elderly
Internal medicine
Medicina interna
Mortality risk
Prognosis
Pronostico
Riesgo de mortalidad

Reducing Delirium and Improving Patient Satisfaction With a Perioperative Mindfulness Intervention: A Mixed-Methods Pilot Study. Lisann-Goldman, L. R. Pagnini, F. Deiner, S. G. Langer, E. J. Holistic Nursing Practice 2019

adult
anxiety
article
controlled study
exercise
female
heart
hospitalization
human
incidence
male
mindfulness
patient satisfaction
pilot study
postoperative delirium
surgery
surgical patient
thorax surgery

Association between Inpatient Delirium and Hospital Readmission in Patients >/= 65 Years of Age: A Retrospective Cohort Study. LaHue, S. C. Douglas, V. C. Kuo, T. Conell, C. A. Liu, V. X. Josephson, S. A. Angel, C. Brooks, K. B. J Hosp Med 2019
Feasibility and acceptability of family administration of delirium detection tools in the intensive care unit: a patient-oriented pilot study. Krewulak, K. D. Sept, B. G. Stelfox, H. T. Ely, E. W. Davidson, J. E. Ismail, Z. Fiest, K. M. CMAJ Open 2019
Diabetes and elevated preoperative hba1c level as risk factors for postoperative delirium after cardiac surgery: An observational cohort study. Kotfis, K. Szylińska, A. Listewnik, M. Brykczyński, M. Ely, E. W. Rotter, I. Neuropsychiatric Disease and Treatment 2019

creatinine
hemoglobin A1c
insulin
oral antidiabetic agent
age
aged
artery disease
article
cohort analysis
controlled study
creatinine blood level
diabetes mellitus
disease association
DSM-5
female
heart failure
heart surgery
hemoglobin blood level
human
major clinical study
male
observational study
postoperative delirium
preoperative period
retrospective study
risk assessment
risk factor

Evaluation of Changes in Functional Status in the Year after Aortic Valve Replacement. Kim, D. H. Afilalo, J. Shi, S. M. Popma, J. J. Khabbaz, K. R. Laham, R. J. Grodstein, F. Guibone, K. Lux, E. Lipsitz, L. A. JAMA Intern Med 2019

aged
aortic valve replacement
article
cohort analysis
data analysis
deterioration
female
follow up
frailty
functional status
human
major clinical study
male
postoperative delirium
priority journal
prospective study
self report
surgical aortic valve replacement
task performance
telephone interview
transcatheter aortic valve implantation
very elderly

Association of electroencephalogram trajectories during emergence from anaesthesia with delirium in the postanaesthesia care unit: an early sign of postoperative complications. Hesse, S. Kreuzer, M. Hight, D. Gaskell, A. Devari, P. Singh, D. Taylor, N. B. Whalin, M. K. Lee, S. Sleigh, J. W. García, P. S. British Journal of Anaesthesia 2019

fentanyl
hydromorphone
ketamine
morphine
nitrous oxide
adult
adverse outcome
aged
alcohol consumption
analgesia
anesthesia
article
cardiovascular disease
cerebrovascular accident
chronic kidney failure
chronic obstructive lung disease
clinical outcome
comorbidity
dementia
disease association
electroencephalogram
electroencephalography monitoring
female
follow up
general anesthesia
hospital readmission
hospitalization
human
kidney failure
length of stay
major clinical study
male
maximum likelihood method
medical history
medical record review
mild cognitive impairment
morbidity
mortality risk
neurologic disease
observational study
orthopedic surgery
pain assessment
Parkinson disease
perioperative period
peroperative care
postoperative care
postoperative complication
postoperative delirium
prediction
priority journal
recovery room
risk factor
spine surgery

Evaluation of a Multidisciplinary Pain, Agitation, and Delirium Guideline in Mechanically Ventilated Critically Ill Adults. Heim, M. Draheim, R. Krupp, A. Breihan, P. O'Rourke, A. Wells, J. Fish, J. Hosp Pharm 2019

analgesics
anesthetics
critical care
respiratory
conflicts of interest with respect to the research, authorship, and/or
publication of this article.

Risk factors for postoperative delirium in patients undergoing microvascular decompression. He, Z. Cheng, H. Wu, H. Sun, G. Yuan, J. PLoS One 2019
Preliminary investigation of predictors of distress in informal caregivers of patients with delirium superimposed on dementia. Grossi, E. Lucchi, E. Gentile, S. Trabucchi, M. Bellelli, G. Morandi, A. Aging Clin Exp Res 2019

Delirium superimposed on dementia
Predictors of distress in caregivers
Stress

Use of the confusion assessment method in multicentre delirium trials: training and standardisation. Green, J. R. Smith, J. Teale, E. Collinson, M. Avidan, M. S. Schmitt, E. M. Inouye, S. K. Young, J. BMC Geriatr 2019

Confusion assessment method
Delirium
Multicentre studies
Training

Distinguishing characteristics of delirium in a skilled nursing facility in Spain: Influence of baseline cognitive status. Franco, J. G. Trzepacz, P. T. Gaviria, A. M. Sepulveda, E. Vinuelas, E. Palma, J. Grau, I. Vilella, E. Int J Geriatr Psychiatry 2019

Delirium
dementia
diagnosis
intermediate care facilities
mild cognitive impairment
skilled nursing facilities

Modifiable Risk Factors for Delirium in Critically Ill Trauma Patients: A Multicenter Prospective Study. Duceppe, M. A. Williamson, D. R. Elliott, A. Para, M. Poirier, M. C. Delisle, M. S. Deckelbaum, D. Razek, T. Desjardins, M. Bertrand, J. C. Bernard, F. Rico, P. Burry, L. Frenette, A. J. Perreault, M. J Intensive Care Med 2019

delirium
intensive care unit
risk factors
trauma

Delirium after hip hemiarthroplasty for proximal femoral fractures in elderly patients: Risk factors and clinical outcomes. de Jong, L. van Rijckevorsel, V. A. J. I. M. Raats, J. W. Klem, T. M. A. L. Kuijper, T. M. Roukema, G. R. Clinical Interventions in Aging 2019

hip prosthesis
Mathys CCA
Palamed G
age
aged
article
clinical outcome
confusion
controlled study
Delirium Observation Screening Scale
dementia
disease association
disease duration
female
geriatric surgery
geriatrician
hip hemiarthroplasty
hospital admission
hospital discharge
hospitalization
human
major clinical study
male
medical record
mortality rate
Netherlands
neurologic examination
nursing home
overall survival
pneumonia
postoperative delirium
prediction
proximal femur fracture
rating scale
retrospective study
risk factor
surgical infection
teaching hospital
time to treatment
urinary tract infection
very elderly

Frailty Identification and Care Pathway: An Interdisciplinary Approach to Care for Older Trauma Patients. Bryant, E. A. Tulebaev, S. Castillo-Angeles, M. Moberg, E. Senglaub, S. S. O'Mara, L. McDonald, M. Salim, A. Cooper, Z. J Am Coll Surg 2019
Validation of the O3DY French Version (O3DY-F) for the Screening of Cognitive Impairment in Community Seniors in the Emergency Department. Bedard, C. Boucher, V. Voyer, P. Yadav, K. Eagles, D. Nadeau, A. Carmichael, P. H. Pelletier, M. Gouin, E. Berthelot, S. Daoust, R. Lague, A. Gagne, A. J. Emond, M. J Emerg Med 2019

cognitive impairment
emergency department
screening tool
seniors
validation

Identification of delirium and subsyndromal delirium in intensive care patients. Bastos, A. S. Beccaria, L. M. Silva, D. C. D. Barbosa, T. P. Rev Bras Enferm 2019
Off-label use of antipsychotics and associated factors in community living older adults. Bakouni, H. Berbiche, D. Vasiliadis, H. M. Aging Ment Health 2019

age
aged
Alzheimer disease
article
Canada
community living
controlled study
drug database
drug therapy
education
female
human
insomnia
insurance
major clinical study
major depression
male
off label drug use
organic brain syndrome
outpatient
prevalence
antidepressant agent
benzodiazepine
neuroleptic agent

Assessment of analgesia, sedation, physical restraint and delirium in patients admitted to Spanish intensive care units. Proyecto ASCyD Arias-Rivera, S. Lopez-Lopez, C. Frade-Mera, M. J. Via-Clavero, G. Rodriguez-Mondejar, J. J. Sanchez-Sanchez, M. M. Acevedo-Nuevo, M. Gil-Castillejos, D. Robleda, G. Cachon-Perez, M. Latorre-Marco, I. Enferm Intensiva 2019

Contenciones mecanicas
Critical care
Cuidados intensivos
Delirio
Delirium
Dolor
Evaluacion en enfermeria
Nursing assessment
Pain
Physical restraint
Sedacion
Sedation

Medication and medical diagnosis as risk factors for falls in older hospitalized patients. Wedmann, F. Himmel, W. Nau, R. Eur J Clin Pharmacol 2019

Accidental falls
Aged
Hospital
Matched case-control study
Mirtazapine
Psychotropic drugs
Serotonin and noradrenaline reuptake inhibitors
Z-drugs

The inclusion of delirium in version 2 of the National Early Warning Score will substantially increase the alerts for escalating levels of care: findings from a retrospective database study of emergency medical admissions in two hospitals. Mohammed, M. A. Faisal, M. Richardson, D. Scally, A. Howes, R. Beatson, K. Irwin, S. Speed, K. Clin Med (London) 2019

News2
National Early Warning Score
alert
delirium
escalation

Factors Associated with Length of Stay in Hospital Patients with and Without Dementia. Möllers, T. Perna, L. Ihle, P. Schubert, I. Bauer, J. Brenner, H. Journal of Alzheimer's Disease 2019

adult
age
aged
article
cohort analysis
controlled study
delirium
delusional disorder
dementia
depression
female
Germany
hallucination
hospitalization
human
length of stay
major clinical study
male
mental disease
priority journal
psychosis
retrospective study
risk factor
very elderly

Does a Year Have 6 Months or 12? Implications for Delirium Detection Among Hospitalized Older General Medicine Patients. Zhou, W. Ngo, L. H. Inouye, S. K. Gallagher, J. Husser, E. K. Fick, D. M. Marcantonio, E. R. Journal of General Internal Medicine 2018

adult
article
delirium
general practice
human

Serum soluble fibrinogen-like protein 2 concentration predicts delirium after acute pancreatitis. Xu, W. B. Hu, Q. H. Wu, C. N. Fan, Z. K. Song, Z. F. Brain Behav 2019

acute pancreatitis
delirium
fibrinogen-like protein 2
severity

Use of the brief Confusion Assessment Method in a veteran palliative care population: A pilot validation study. Wilson, J. E. Boehm, L. Samuels, L. R. Unger, D. Leonard, M. Roumie, C. Ely, E. W. Dittus, R. S. Misra, S. Han, J. H. Palliat Support Care 2019

cognition
delirium
end-of-life
palliative care
screening

Relative cerebral hyperperfusion during cardiopulmonary bypass is associated with risk for postoperative delirium: a cross-sectional cohort study. Thudium, M. Ellerkmann, R. K. Heinze, I. Hilbert, T. BMC Anesthesiology 2019

Cardiac surgery
Cardiopulmonary bypass
Cerebral blood flow
Delirium
Transcranial Doppler sonography

Prediction of postoperative delirium by comprehensive geriatric assessment among elderly patients with hip fracture. Tao, L. Xiaodong, X. Qiang, M. Jiao, L. Xu, Z. Ir J Med Sci 2019

Comprehensive geriatric assessment
Elderly
Hip fracture
Postoperative delirium