What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Intravenous versus inhalational maintenance of anaesthesia for postoperative cognitive outcomes in elderly people undergoing non-cardiac surgery.
- Authors
- Miller, D. Lewis, S. R. Pritchard, M. W. Schofield-Robinson, O. J. Shelton, C. L. Alderson, P. Smith, A. F.
- Year
- 2018
- Journal
- Cochrane Database of Systematic Reviews
- Abstract
BACKGROUND: The use of anaesthetics in the elderly surgical population (more than 60 years of age) is increasing. Postoperative delirium, an acute condition characterized by reduced awareness of the environment and a disturbance in attention, typically occurs between 24 and 72 hours after surgery and can affect up to 60% of elderly surgical patients. Postoperative cognitive dysfunction (POCD) is a new-onset of cognitive impairment which may persist for weeks or months after surgery.Traditionally, surgical anaesthesia has been maintained with inhalational agents. End-tidal concentrations require adjustment to balance the risks of accidental awareness and excessive dosing in elderly people. As an alternative, propofol-based total intravenous anaesthesia (TIVA) offers a more rapid recovery and reduces postoperative nausea and vomiting. Using TIVA with a target controlled infusion (TCI) allows plasma and effect-site concentrations to be calculated using an algorithm based on age, gender, weight and height of the patient.TIVA is a viable alternative to inhalational maintenance agents for surgical anaesthesia in elderly people. However, in terms of postoperative cognitive outcomes, the optimal technique is unknown. OBJECTIVES: To compare maintenance of general anaesthesia for elderly people undergoing non-cardiac surgery using propofol-based TIVA or inhalational anaesthesia on postoperative cognitive function, mortality, risk of hypotension, length of stay in the postanaesthesia care unit (PACU), and hospital stay. SEARCH METHODS: We searched the Cochrane Central Register of Controlled Trials (CENTRAL; 2017, Issue 11), MEDLINE (1946 to November 2017), Embase (1974 to November 2017), PsycINFO (1887 to November 2017). We searched clinical trials registers for ongoing studies, and conducted backward and forward citation searching of relevant articles. SELECTION CRITERIA: We included randomized controlled trials (RCTs) with participants over 60 years of age scheduled for non-cardiac surgery under general anaesthesia. We planned to also include quasi-randomized trials. We compared maintenance of anaesthesia with propofol-based TIVA versus inhalational maintenance of anaesthesia. DATA COLLECTION AND ANALYSIS: Two review authors independently assessed studies for inclusion, extracted data, assessed risk of bias, and synthesized findings. MAIN RESULTS: We included 28 RCTs with 4507 randomized participants undergoing different types of surgery (predominantly cardiovascular, laparoscopic, abdominal, orthopaedic and ophthalmic procedures). We found no quasi-randomized trials. Four studies are awaiting classification because we had insufficient information to assess eligibility.All studies compared maintenance with propofol-based TIVA versus inhalational maintenance of anaesthesia. Six studies were multi-arm and included additional TIVA groups, additional inhalational maintenance or both. Inhalational maintenance agents included sevoflurane (19 studies), isoflurane (eight studies), and desflurane (three studies), and was not specified in one study (reported as an abstract). Some studies also reported use of epidural analgesia/anaesthesia, fentanyl and remifentanil.We found insufficient reporting of randomization methods in many studies and all studies were at high risk of performance bias because it was not feasible to blind anaesthetists to study groups. Thirteen studies described blinding of outcome assessors. Three studies had a high of risk of attrition bias, and we noted differences in the use of analgesics between groups in six studies, and differences in baseline characteristics in five studies. Few studies reported clinical trials registration, which prevented assessment of risk of selective reporting bias.We found no evidence of a difference in incidences of postoperative delirium according to type of anaesthetic maintenance agents (odds ratio (OR) 0.59, 95% confidence interval (CI) 0.15 to 2.26; 321 participants; five studies; very low-certainty evidence); we noted during sensitivity analysis that using different time points in one study may influence direction of this result. Thirteen studies (3215 participants) reported POCD, and of these, six studies reported data that could not be pooled; we noted no difference in scores of POCD in four of these and in one study, data were at a time point incomparable to other studies. We excluded one large study from meta-analysis because study investigators had used non-standard anaesthetic management and this study was not methodologically comparable to other studies. We combined data for seven studies and found low-certainty evidence that TIVA may reduce POCD (OR 0.52, 95% CI 0.31 to 0.87; 869 participants).We found no evidence of a difference in mortality at 30 days (OR 1.21, 95% CI 0.33 to 4.45; 271 participants; three studies; very low-certainty evidence). Twelve studies reported intraoperative hypotension. We did not perform meta-analysis for 11 studies for this outcome. We noted visual inconsistencies in these data, which may be explained by possible variation in clinical management and medication used to manage hypotension in each study (downgraded to low-certainty evidence); one study reported data in a format that could not be combined and we noted little or no difference between groups in intraoperative hypotension for this study. Eight studies reported length of stay in the PACU, and we did not perform meta-analysis for seven studies. We noted visual inconsistencies in these data, which may be explained by possible differences in definition of time points for this outcome (downgraded to very low-certainty evidence); data were unclearly reported in one study. We found no evidence of a difference in length of hospital stay according to type of anaesthetic maintenance agent (mean difference (MD) 0 days, 95% CI -1.32 to 1.32; 175 participants; four studies; very low-certainty evidence).We used the GRADE approach to downgrade the certainty of the evidence for each outcome. Reasons for downgrading included: study limitations, because some included studies insufficiently reported randomization methods, had high attrition bias, or high risk of selective reporting bias; imprecision, because we found few studies; inconsistency, because we noted heterogeneity across studies. AUTHORS’ CONCLUSIONS: We are uncertain whether maintenance with propofol-based TIVA or with inhalational agents affect incidences of postoperative delirium, mortality, or length of hospital stay because certainty of the evidence was very low. We found low-certainty evidence that maintenance with propofol-based TIVA may reduce POCD. We were unable to perform meta-analysis for intraoperative hypotension or length of stay in the PACU because of heterogeneity between studies. We identified 11 ongoing studies from clinical trials register searches; inclusion of these studies in future review updates may provide more certainty for the review outcomes.
- PMID
- Keywords
Aged
Anesthesia, Inhalation
Anesthesia, Intravenous
Anesthetics, Inhalation
Anesthetics, Intravenous/*adverse effects
Cognition/*drug effects
Cognition Disorders/chemically induced
Delirium/chemically induced
Desflurane
Humans
Hypotension/chemically induced
Isoflurane/adverse effects/analogs & derivatives
Methyl Ethers/adverse effects
Middle Aged
Postoperative Complications/chemically induced/mortality
Propofol/*adverse effects
Randomized Controlled Trials as Topic
Sevoflurane
*Surgical Procedures, Operative
- Page(s)
- Volume
- 8
- Issue
Title | Authors | Journal | Year | Keywords | |
---|---|---|---|---|---|
Comparison of pharmacological and non-pharmacological interventions to prevent delirium in critically ill patients: a protocol for a systematic review incorporating network meta-analyses. | Burry LD, Hutton B, Guenette M, Williamson D, Mehta S, Egerod I, Kanji S, Adhikari NK, Moher D, Martin CM, Rose L | Systematic reviews | 2016 | ||
Unraveling the Relationship Between Delirium, Brain Damage, and Subsequent Cognitive Decline in a Cohort of Individuals Undergoing Surgery for Hip Fracture. | Beishuizen SJ, Scholtens RM, van Munster BC, de Rooij SE | Journal of the American Geriatrics Society | 2016 | ||
Standardizing Management of Adults with Delirium Hospitalized on Medical-Surgical Units. | Angel C, Brooks K, Fourie J | The Permanente journal | 2016 | ||
The utility of the clock drawing test in detection of delirium in elderly hospitalised patients. | Adamis D, Meagher D, O'Neill D, McCarthy G | Aging & mental health | 2016 | ||
Effect of New Cerebral Ischemic Lesions on the Delirium Occurrence After Transcatheter Aortic Valve Replacement. | Abawi M, Nijhoff F, Agostoni P, de Vries R, Slooter AJ, Emmelot-Vonk MH, Voskuil M, Leiner T, Doevendans PA, Stella PR | Journal of the American College of Cardiology | 2016 | ||
Is cobalamin deficiency associated with increased risk of all subtypes of postoperative delirium? | Wang LK, Lan KM, Lin YT, Chen JY | Neuropsychiatric disease and treatment | 2016 | ||
Meeting the Challenges of Delirium Assessment Across the Aging Spectrum. | Smith HA, Han JH, Ely EW | Critical care medicine | 2016 | ||
Response to Paul Regal. | Schmitt EM, Inouye SK | Journal of the American Geriatrics Society | 2016 | ||
Is delirium the medical emergency we know least about? | Nagaraj G, Burkett E, Hullick C, Carpenter CR, Arendts G | Emergency medicine Australasia : EMA | 2016 | ||
Earplugs might reduce intensive care unit delirium but quality of evidence is low. | Law AC, Walkey AJ | Evidence-based medicine | 2016 | ||
The major risk factors for delirium in a clinical setting. | Kim H, Chung S, Joo YH, Lee JS | Neuropsychiatric disease and treatment | 2016 | ||
Prevalence, determinants, and prognostic significance of delirium in patients with acute heart failure. | Honda S, Nagai T, Sugano Y, Okada A, Asaumi Y, Aiba T, Noguchi T, Kusano K, Ogawa H, Yasuda S, Anzai T, | International journal of cardiology | 2016 | ||
Delirium in older adults: a chronic cognitive disorder? | Cole MG, Mccusker J | International psychogeriatrics / IPA | 2016 | ||
Sedative choice and ventilator-associated patient outcomes: don't sleep on delirium. | Barnes SS, Kudchadkar SR | Annals of translational medicine | 2016 | ||
The use of volunteers to help older medical patients mobilise in hospital: a systematic review. | Baczynska AM, Lim SE, Sayer AA, Roberts HC | Journal of clinical nursing | 2016 | ||
The Geriatric Day Hospital: Preliminary Data on an Innovative Model of Care in Brazil for Older Adults at Risk of Hospitalization. | Aliberti MJ, Suemoto CK, Fortes-Filho SQ, Melo JA, Trindade CB, Kasai JY, Altona M, Apolinario D, Jacob-Filho W | Journal of the American Geriatrics Society | 2016 | ||
Long-Term Mental Health Problems After Delirium in the ICU. | Wolters AE, Peelen LM, Welling MC, Kok L, de Lange DW, Cremer OL, van Dijk D, Slooter AJ, Veldhuijzen DS | Critical care medicine | 2016 | ||
Delirium assessment in hospitalized elderly patients: Italian translation and validation of the nursing delirium screening scale. | Spedale V, Di Mauro S, Del Giorno G, Barilaro M, Villa CE, Gaudreau JD, Ausili D | Aging clinical and experimental research | 2016 | ||
Insulin-like growth factor-1, a potential predicative biomarker for postoperative delirium among elderly patients with open abdominal surgery. | Shen H, Shao Y, Chen J, Guo J | Current pharmaceutical design | 2016 | ||
Delirium the under-recognised syndrome: survey of healthcare professionals' awareness and practice in the intensive care units. | Selim AA, Wesley Ely E | Journal of clinical nursing | 2017 |
Adult, Attitude of Health Personnel, Critical Care, organization & administration, Cross-Sectional Studies, Delirium, diagnosis, Disease Management, Egypt, Female, Health Care Surveys, Health Knowledge, Attitudes, Practice, Health Personnel, psychology, Humans, Intensive Care Units, organization & administration, Male, Middle Aged, Nursing Staff, Hospital, psychology, Physicians, psychology, Surveys and Questionnaires |
|
Intra-operative events during cardiac surgery are risk factors for the development of delirium in the ICU. | Rudiger A, Begdeda H, Babic D, Krüger B, Seifert B, Schubert M, Spahn DR, Bettex D | Critical care (London, England) | 2016 | ||
Validity and Reliability of the 6-Item Cognitive Impairment Test for Screening Cognitive Impairment: A Review. | O'Sullivan D, O'Regan NA, Timmons S | Dementia and geriatric cognitive disorders | 2016 | ||
Delirium in elderly patients: association with educational attainment. | Martins S, Paiva JA, Simões MR, Fernandes L | Acta neuropsychiatrica | 2017 |
Aged, Aged, 80 and over, Cognitive Reserve, Delirium, epidemiology, Educational Status, Female, Glasgow Coma Scale, Humans, Male, Portugal, epidemiology, Psychiatric Status Rating Scales |
|
Prevalence of Delirium in Older Medical Inpatients in Tanzania. | Lewis E, Paddick SM, Banks J, Duinmaijer A, Tucker L, Kisoli A, Cletus J, Lissu C, Dotchin C, Gray W, Walker R, Urasa S | Journal of the American Geriatrics Society | 2016 | ||
Preventing postoperative delirium: all that glisters is not gold. | Kronzer VL, Avidan MS | Lancet (London, England) | 2016 | ||
Trajectory of Functional Recovery After Postoperative Delirium in Elective Surgery. | Hshieh TT, Saczynski J, Gou RY, Marcantonio E, Jones RN, Schmitt E, Cooper Z, Ayres D, Wright J, Travison TG, Inouye SK, | Annals of surgery | 2017 | ||
Evaluation of delirium screening tools in geriatric medical inpatients: a diagnostic test accuracy study. | Hendry K, Quinn TJ, Evans J, Scortichini V, Miller H, Burns J, Cunnington A, Stott DJ | Age and ageing | 2016 | ||
Mind Over Matter? The Hidden Epidemic of Cognitive Dysfunction in the Older Surgical Patient. | O' Brien H, Mohan H, Hare CO, Reynolds JV, Kenny RA | Annals of surgery | 2016 | ||
The Impact of Interventions to Improve Sleep on Delirium in the ICU: A Systematic Review and Research Framework. | Flannery AH, Oyler DR, Weinhouse GL | Critical care medicine | 2016 | ||
Neuroinflammatory challenges compromise neuronal function in the aging brain: Postoperative cognitive delirium and Alzheimer's disease. | Cortese GP, Burger C | Behavioural brain research | 2016 | ||
Delirium: Time to climb this babylon tower. | Capponi MG, Biffi AM, Spada MS, Ansaloni L | European journal of internal medicine | 2017 | ||
Preventing delirium: beyond dexmedetomidine. | Avramescu S, Wang DS, Choi S, Orser BA | Lancet (London, England) | 2017 | ||
Prevalence and Risk Factors for Delirium in Acute Stroke Patients. A Retrospective 5-Years Clinical Series. | Alvarez-Perez FJ, Paiva F | Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association | 2017 | ||
An evolving approach to delirium: A mixed-methods process evaluation of a hospital-wide delirium program in New Zealand. | Alhaidari AA, Allen-Narker RA | Australasian journal on ageing | 2017 | ||
Delirium superimposed on dementia: phenomenological differences between patients with and without behavioral and psychological symptoms of dementia in a specialized delirium unit. | Abengaña J, Chong MS, Tay L | International psychogeriatrics | 2017 | ||
Incidence, risk factors and outcomes of delirium in intensive care unit of universiti kebangsaan malaysia medical centre | Vyveganathan, L., Izaham, A., Mohamad Yusof, A., Wan Mat, W. R., Abdul Rahman, R., Abdul Manap, N. | Anesthesia and Analgesia | 2016 |
bilirubin |
|
Influence of acute delirium on short-term prognosis in elderly acute decompensated heart failure patients | Tagahara, K., Azioka, M., Nakashima, Y., Osanai, H., Inoue, Y., Kanbara, T., Yoshida, T., Masutomi, T., Ohashi, H., Tobe, A. | Journal of Cardiac Failure | 2016 |
acute heart failure |
|
Implementing a delirium prevention programme can reduce falls in hospital geriatric medicine wards | Solomonsz, A., Charalambous, L., Taylor, R., Blackshaw, E., Ali, A., Morris, R., Moorchilot, R., Poon, M., Blundell, A., Harwood, R., Masud, T. | European Geriatric Medicine | 2016 | ||
Emergence delirium in adult patients after general anaesthesia-a prospective study from the caribbean | Ramroop, R., Hariharan, S., Chen, D. | Anesthesia and Analgesia | 2016 |
atropine |
|
Optimized anesthesia to reduce incidence of postoperative delirium in elderly undergoing elective, non-cardiac surgery: A randomized controlled trial | Punjasawadwong, Y., Pipanmekaporn, T., Wongpakaran, N. | Anesthesia and Analgesia | 2016 |
aged |
|
Evaluation of the idea (identification and interventions for dementia in elderly Africans) brief cognitive screening tool for identification of delirium in older hospitalised adults in Tanzania | Paddick, S. M., Lewis, E. G., Duinmaijer, A. T., Banks, J., Urasa, S., Tucker, L., Kisoli, A., Cletus, J., Lissu, C., Kisima, J., Dotchin, C., Gray, W. K., Mushi, D., Walker, R. | Alzheimer's and Dementia | 2016 |
adult |
|
Effectiveness of Educational Enhancement for Clinicians Regarding Understanding and Applying Confusion Assessment Method in the ICU (CAM-ICU) | Pandya, T., Hanna, M., Ghazarian, Z., Sekhon, R., Ismail, M. | CHEST | 2016 | ||
Improving the detection of delirium, depression and suspected dementia in community hospital settings | North, C., Russell, G., Hayes, N. | European Geriatric Medicine | 2016 |
community hospital |
|
127 Emergency Department Interventions and Their Effect on Delirium's Natural Course: The Folly May Be in the Foley | Noel, C., Cirbus, J., Han, J.H. | Annals of Emergency Medicine | 2016 |
Delirium Geriatrics Psychiatry |
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Identifying and managing delirium on admission | Musaddaq, B., Bakshi, P., Roseman, H., Pleming, J., Saber, S., Wu, A., Mizoguchi, R. | European Geriatric Medicine | 2016 |
aged |
|
Association between mini nutritional assessment (MNA) and the development of delirium in elderly patients with hip fracture | Lozano-Montoya, I., Miret-Corchado, C., Vaquero-Pinto, M. N., Roldán-Plaza, C., Sánchez-García, E., Cruz-Jentoft, A. | European Geriatric Medicine | 2016 |
aged |
|
Comparison between cerebrolysin and citicoline in the incidence of postoperative delirium in adult cardiac surgical patients | Lespron, M. D. C., Morales, O., Molina, F. J., Figueroa, J., Suárez, L., Molina, A., Guerrero, R., Alvarez, H., Telona, E. J. | Anesthesia and Analgesia | 2016 |
cerebrolysin |
|
A comparison between confusion assessment method in intensive care unit (CAM-ICU) and neelon-champagne (NEECHAM) confusion scale | Karci, O., Serin, S., Sungurtekin, H. | 2016 |
adult |
||
Promoting Sleep to Improve Delirium in the ICU∗ | Kamdar, B. B., Martin, J. L., Needham, D. M., Ong, M. K. | Critical Care Medicine | 2016 |
critical illness |
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Delirium as a non-traumatic brain injury: Older patients with delirium have similar biomarker profiles to patients with isolated traumatic brain injury | Jackson, T. A., Shears, B., Lord, J. M., Belli, A., Hazeldine, J. | European Geriatric Medicine | 2016 |
biological marker |
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Comprehensive geriatric assessment for prevention of delirium post hip fracture: A systematic review of randomised controlled trials | Henderson, V., Shields, L., Clasake, R. | European Geriatric Medicine | 2016 |
|
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Long-term prognostic value of DELIRIUM in elderly patients with acute Cardiac diseases admitted to two cardiac intensive care unit: A prospective study | Grotti, S., Falsini, G., Porto, I., Toccafondi, G., Fraticelli, A., Angioli, P., Ducci, K., Liistro, F., Pieroni, M., Taddei, T., Romanelli, S., Rossie, R., Bolognese, L. | European Heart Journal: Acute Cardiovascular Care | 2016 |
|
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Hospitalised older people with dementia and delirium: More readmissions and in-hospital complications, greater length of stay and associated healthcare costs | Giudice, D. L., Tropea, J., Brand, C.A., Gorelik, A. Liew, D. | Alzheimer's and Dementia | 2016 |
Australia |
|
Progressive brain atrophy and cognitive decline along with multiple episodes of delirium. | Hayakawa K, Kato TA, Imamura S, Kasai N, Kanba S | Psychiatry and clinical neurosciences | 2017 | ||
Case of insulinoma manifesting as hyperinsulinemia after discontinuing quetiapine in an elderly patient with delirium. | Yamamoto N, Oh E, Nishiyama K, Yoshida M, Saeki A, Ishii H, Takeda Y, Hamahata T, Sugino M | Geriatrics & gerontology international | 2017 | ||
A National Multicenter Survey on Management of Pain, Agitation, and Delirium in Intensive Care Units in China. | Wang J, Peng ZY, Zhou WH, Hu B, Rao X, Li JG | Chinese medical journal | 2017 | ||
High C-Reactive Protein Predicts Delirium Incidence, Duration, and Feature Severity After Major Noncardiac Surgery. | Vasunilashorn SM, Dillon ST, Inouye SK, Ngo LH, Fong TG, Jones RN, Travison TG, Schmitt EM, Alsop DC, Freedman SD, Arnold SE, Metzger ED, Libermann TA, Marcantonio ER | Journal of the American Geriatrics Society | 2017 | ||
Interventions to Reduce Postoperative Delirium: Aligning Surgical Care With Patients' Needs and Priorities. | Suwanabol PA, Hinshaw DB | JAMA surgery | 2017 | ||
Assessment of Delirium in Intensive Care Unit Patients: Educational Strategies. | Smith JM, Van Aman MN, Schneiderhahn ME, Edelman R, Ercole PM | Journal of continuing education in nursing | 2017 | ||
Pathophysiological and behavioral effects of systemic inflammation in aged and diseased rodents with relevance to delirium: A systematic review. | Schreuder L, Eggen BJ, Biber K, Schoemaker RG, Laman JD, de Rooij SE | Brain, behavior, and immunity | 2017 | ||
Effectiveness of haloperidol prophylaxis in critically ill patients with a high risk of delirium: a systematic review. | Santos E, Cardoso D, Neves H, Cunha M, Rodrigues M, Apóstolo J | JBI database of systematic reviews and implementation reports | 2017 | ||
Survey among critical care nurses and physicians about delirium management. | Nydahl P, Dewes M, Dubb R, Hermes C, Kaltwasser A, Krotsetis S, von Haken R | Nursing in critical care | 2017 | ||
Recognition of Delirium in Postoperative Elderly Patients: A Multicenter Study. | Numan T, van den Boogaard M, Kamper AM, Rood PJT, Peelen LM, Slooter AJC, | Journal of the American Geriatrics Society | 2017 | ||
Preoperative Cognitive Performance and Postoperative Delirium Are independently Associated With Future Dementia in Older People Who Have Undergone Cardiac Surgery: A Longitudinal Cohort Study. | Lingehall HC, Smulter NS, Lindahl E, Lindkvist M, Engström KG, Gustafson YG, Olofsson B | Critical care medicine | 2017 | ||
Effects of nimodipine on postoperative delirium in elderly under general anesthesia: A prospective, randomized, controlled clinical trial. | Li YN, Zhang Q, Yin CP, Guo YY, Huo SP, Wang L, Wang QJ | Medicine | 2017 | ||
Low plasma leptin level at admission predicts delirium in critically ill patients: A prospective cohort study. | Li G, Lei X, Ai C, Li T, Chen Z | Peptides | 2017 | ||
Sleep-Disordered Breathing, Postoperative Delirium, and Cognitive Impairment. | Lam EWK, Chung F, Wong J | Anesthesia and analgesia | 2017 | ||
Perceived Stigma and Quality of Life in Patients Following Recovery From Delirium. | Kim SY, Kim JM, Kim SW, Kang HJ, Lee JY, Bae KY, Shin IS, Yoon JS | The Journal of clinical psychiatry | 2017 | ||
Evaluation of algorithms to identify delirium in administrative claims and drug utilization database. | Kim DH, Lee J, Kim CA, Huybrechts KF, Bateman BT, Patorno E, Marcantonio ER | Pharmacoepidemiology and drug safety | 2017 | ||
Direct evidence of central nervous system axonal damage in patients with postoperative delirium: A preliminary study of pNF-H as a promising serum biomarker. | Inoue R, Sumitani M, Ogata T, Chikuda H, Matsubara T, Kato S, Shimojo N, Uchida K, Yamada Y | Neuroscience letters | 2017 | ||
HELP! Problems in executing a pragmatic, randomized, stepped wedge trial on the Hospital Elder Life Program to prevent delirium in older patients. | Heim N, van Stel HF, Ettema RG, van der Mast RC, Inouye SK, Schuurmans MJ | Trials | 2017 | ||
A Systematic Review and Meta-analysis Examining the Impact of Incident Postoperative Delirium on Mortality. | Hamilton GM, Wheeler K, Di Michele J, Lalu MM, McIsaac DI | Anesthesiology | 2017 | ||
A Novel Computerized Test for Detecting and Monitoring Visual Attentional Deficits and Delirium in the ICU. | Green C, Hendry K, Wilson ES, Walsh T, Allerhand M, MacLullich AMJ, Tieges Z | Critical care medicine | 2017 | ||
Network for Investigation of Delirium Across the U.S. (NIDUS): Advancing the Field of Delirium with a New Interdisciplinary Research Network. | Fick DM, Auerbach AD, Avidan MS, Busby-Whitehead J, Ely EW, Jones RN, Marcantonio ER, Needham DM, Pandharipande P, Robinson TN, Schmitt EM, Travison TG, Inouye SK | Journal of gerontological nursing | 2017 | ||
Pathway from Delirium to Death: Potential In-Hospital Mediators of Excess Mortality. | Dharmarajan K, Swami S, Gou RY, Jones RN, Inouye SK | Journal of the American Geriatrics Society | 2017 | ||
Effect of a Modified Hospital Elder Life Program on Delirium and Length of Hospital Stay in Patients Undergoing Abdominal Surgery: A Cluster Randomized Clinical Trial. | Chen CC, Li HC, Liang JT, Lai IR, Purnomo JDT, Yang YT, Lin BR, Huang J, Yang CY, Tien YW, Chen CN, Lin MT, Huang GH, Inouye SK | JAMA surgery | 2017 | ||
Predicting inpatient delirium: The AWOL delirium risk-stratification score in clinical practice. | Brown EG, Josephson SA, Anderson N, Reid M, Lee M, Douglas VC | Geriatric nursing (New York, N.Y.) | 2017 | ||
Organizational Domains and Variation in Attitudes of Intensive Care Providers Toward the ABCDE Bundle. | Boehm LM, Vasilevskis EE, Dietrich MS, Wells N, Ely EW, Pandharipande P, Mion LC | American journal of critical care : an official publication, American Association of Critical-Care Nurses | 2017 | ||
Delirium: a guide for the general physician. | Todd OM, Teale EA | Clinical medicine (London, England) | 2017 | ||
Delirium in critically ill patients. | Bergeron N, Skrobik Y, Dubois MJ | Critical care (London, England) | 2002 |
Critical Illness, Delirium, diagnosis, Humans, Intensive Care Units, Neuropsychological Tests, Respiration, Artificial |
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New or Worsening Symptoms and Signs in Community-Dwelling Persons with Dementia: Incidence and Relation to Use of Acute Medical Services. | Sloane PD, Schifeling CH, Beeber AS, Ward KT, Reed D, Gwyther LP, Matchar B, Zimmerman S | Journal of the American Geriatrics Society | 2017 | ||
Nursing care for people with delirium superimposed on dementia. | Pryor C, Clarke A | Nursing older people | 2017 |
Aged, Delirium, complications, Dementia, complications, Humans |
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Functional connectivity and network analysis during hypoactive delirium and recovery from anesthesia. | Numan T, Slooter AJC, van der Kooi AW, Hoekman AML, Suyker WJL, Stam CJ, van Dellen E | Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology | 2017 | ||
Can a 10-Minute Questionnaire Identify Significant Psychological Issues in Patients With Temporomandibular Joint Disease? | Lin SL, Wu SL, Huang HT, Lung FW, Chi TC, Yang JW | Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons | 2017 | ||
The incidence of delirium after cardiac surgery in the elderly: protocol for a systematic review and meta-analysis. | Liao Y, Flaherty JH, Yue J, Wang Y, Deng C, Chen L | BMJ open | 2017 | ||
Polypharmacy and Delirium in Critically Ill Older Adults: Recognition and Prevention. | Garpestad E, Devlin JW | Clinics in geriatric medicine | 2017 | ||
Feasibility of melatonin for prevention of delirium in critically ill patients: a protocol for a multicentre, randomised, placebo-controlled study. | Burry L, Scales D, Williamson D, Foster J, Mehta S, Guenette M, Fan E, Detsky M, Azad A, Bernard F, Rose L | BMJ open | 2017 | ||
Association between delirium superimposed on dementia and mortality in hospitalized older adults: A prospective cohort study. | Avelino-Silva TJ, Campora F, Curiati JA, Jacob-Filho W | PLoS medicine | 2017 | ||
Occupational therapy for delirium management in elderly patients without mechanical ventilation in an intensive care unit. A pilot randomized clinical trial. | Álvarez EA, Garrido MA, Tobar EA, Prieto SA, Vergara SO, Briceño CD, González FJ | Journal of critical care | 2017 | ||
The Effect of Treatment of Anemia with Blood Transfusion on Delirium: A Systematic Review. | van der Zanden V, Beishuizen SJ, Swart LM, de Rooij SE, van Munster BC | Journal of the American Geriatrics Society | 2017 | ||
The neuropsychology of delirium: advancing the science of delirium assessment. | Tieges Z, Evans JJ, Neufeld KJ, MacLullich AM | International journal of geriatric psychiatry | 2017 | ||
The Comparative Risk of Delirium with Different Opioids: A Systematic Review. | Swart LM, van der Zanden V, Spies PE, de Rooij SE, van Munster BC | Drugs & aging | 2017 | ||
Postoperative delirium guidelines: The greater the obstacle, the more glory in overcoming it. | Steiner LA | European journal of anaesthesiology | 2017 | ||
Nurses' training in the use of a delirium screening tool. | Souza RCDS, Bersaneti MDR, Siqueira EMP, Meira L, Brumatti DL, Prado NRO | Revista gaucha de enfermagem | 2017 | ||
Factors predicting incidence of post-operative delirium in older people following hip fracture surgery: a systematic review and meta-analysis. | Smith TO, Cooper A, Peryer G, Griffiths R, Fox C, Cross J | International journal of geriatric psychiatry | 2017 | ||
Postoperative confusion in older adults. | Segal-Gidan F | JAAPA : official journal of the American Academy of Physician Assistants | 2017 | ||
Critical care nurses' knowledge and practice of delirium assessment. | Rowley-Conwy G | British journal of nursing (Mark Allen Publishing) | 2017 | ||
Inattention tests for delirium. | Regal P | International psychogeriatrics | 2017 | ||
Post-Liver Transplant Delirium Increases Mortality and Length of Stay. | Oliver N, Bohorquez H, Anders S, Freeman A, Fine K, Ahmed E, Bruce DS, Carmody IC, Cohen AJ, Seal J, Reichman TW, Loss GE | The Ochsner journal | 2017 | ||
Debating the Role of Arousal in Delirium Diagnosis: Should Delirium Diagnosis Be Inclusive or Restrictive? | Oldham MA, Flaherty JH, Rudolph JL | Journal of the American Medical Directors Association | 2017 |