What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Impaired glucose utilization in the brain of patients with delirium following hip fracture
- Authors
- Titlestad, I. Watne, L. O. Caplan, G. A. McCann, A. Ueland, P. M. Neerland, B. E. Myrstad, M. Halaas, N. B. Pollmann, C. T. Henjum, K. Ranhoff, A. H. Solberg, L. B. Figved, W. Cunningham, C. Giil, L. M.
- Year
- 2024
- Journal
- Brain
- Abstract
Alterations in brain energy metabolism have long been proposed as one of several neurobiological processes contributing to delirium. This is supported by previous findings of altered CSF lactate and neuron-specific enolase concentrations and decreased glucose uptake on brain-PET in patients with delirium. Despite this, there are limited data on metabolic alterations found in CSF samples, and targeted metabolic profiling of CSF metabolites involved in energy metabolism has not been performed. The aim of the study was to investigate whether metabolites related to energy metabolism in the serum and CSF of patients with hip fracture are associated with delirium. The study cohort included 406 patients with a mean age of 81 years (standard deviation 10 years), acutely admitted to hospital for surgical repair of a hip fracture. Delirium was assessed daily until the fifth postoperative day. CSF was collected from all 406 participants at the onset of spinal anaesthesia, and serum samples were drawn concurrently from 213 participants. Glucose and lactate in CSF were measured using amperometry, whereas plasma glucose was measured in the clinical laboratory using enzymatic photometry. Serum and CSF concentrations of the branched-chain amino acids, 3-hydroxyisobutyric acid, acetoacetate and β-hydroxybutyrate were measured using gas chromatography-tandem mass spectrometry (GC-MS/MS). In total, 224 (55%) patients developed delirium pre- or postoperatively. Ketone body concentrations (acetoacetate, β-hydroxybutyrate) and branched-chain amino acids were significantly elevated in the CSF but not in serum among patients with delirium, despite no group differences in glucose concentrations. The level of 3-hydroxyisobutyric acid was significantly elevated in both CSF and serum. An elevation of CSF lactate during delirium was explained by age and comorbidity. Our data suggest that altered glucose utilization and a shift to ketone body metabolism occurs in the brain during delirium.
- PMID
PMID:37658825
- Keywords
Humans, Aged, 80 and over, Glucose/metabolism, Acetoacetates
3-Hydroxybutyric Acid, Delirium, Tandem Mass Spectrometry, Hip Fractures/complications/surgery, Brain/diagnostic imaging/metabolism, Lactates, Amino Acids, Branched-Chain, 3-hydroxyisobutyrate, acetoacetate, branched-chain amino acids, lactate, β-hydroxybutyrate
- Page(s)
- Volume
- Issue
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| Use of a Multimodal Implementation Strategy to Improve Delirium Screening by Nurses on an Acute Care for Elders Unit. | Afriyie-Boateng M, Loftus C, Hamelin MA | Worldviews on evidence-based nursing / Sigma Theta Tau International, Honor Society of Nursing | 2015 | |
| Benzodiazepine-associated delirium in critically ill adults. | Zaal IJ, Devlin JW, Hazelbag M, Klein Klouwenberg PM, van der Kooi AW, Ong DS, Cremer OL, Groenwold RH, Slooter AJ | Intensive care medicine | 2015 | |
| Dopamine Administration is a Risk Factor for Delirium in Patients Undergoing Coronary Artery Bypass Surgery. | Yilmaz S, Aksoy E, Diken AI, Yalcinkaya A, Erol ME, Cagli K | Heart, lung & circulation | 2016 | |
| Different MMSE Score Is Associated with Postoperative Delirium in Young-Old and Old-Old Adults. | Wu Y, Shi Z, Wang M, Zhu Y, Li C, Li G, Marcantonio ER, Xie Z, Shen Y | PloS one | 2015 | |
| Methylprednisolone in patients undergoing cardiopulmonary bypass (SIRS): a randomised, double-blind, placebo-controlled trial. | Whitlock RP, Devereaux PJ, Teoh KH, Lamy A, Vincent J, Pogue J, Paparella D, Sessler DI, Karthikeyan G, Villar JC, Zuo Y, Avezum Á, Quantz M, Tagarakis GI, Shah PJ, Abbasi SH, Zheng H, Pettit S, Chrolavicius S, Yusuf S, | Lancet (London, England) | 2015 |
Aged, Aged, 80 and over, Anti-Inflammatory Agents, therapeutic use, Cardiopulmonary Bypass, adverse effects, Double-Blind Method, Female, Humans, Male, Methylprednisolone, therapeutic use, Middle Aged, Systemic Inflammatory Response Syndrome, etiology |
| Does Apolipoprotein E Genotype Increase Risk of Postoperative Delirium? | Vasunilashorn SM, Ngo L, Kosar CM, Fong TG, Jones RN, Inouye SK, Marcantonio ER | The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry | 2015 | |
| New aspects of delirium in elderly patients with critical limb ischemia. | van Eijsden WA, Raats JW, Mulder PG, van der Laan L | Clinical interventions in aging | 2015 | |
| Incidence of and Risk Factors for Delirium After Cardiac Surgery at a Quaternary Care Center: A Retrospective Cohort Study. | Tse L, Schwarz SK, Bowering JB, Moore RL, Barr AM | Journal of cardiothoracic and vascular anesthesia | 2015 | |
| Is delirium being detected in emergency? | Traynor V, Cordato N, Burns P, Xu Y, Britten N, Duncan K, DeVries L, McKinnon C | Australasian journal on ageing | 2016 |
Age Factors, Aged, Cognition, Delirium, diagnosis, Diagnostic Errors, Emergency Services, Psychiatric, Female, Geriatric Assessment, Hospitals, Urban, Humans, Incidence, Male, Medical Audit, Medical Records, New South Wales, epidemiology, Predictive Value of Tests, Psychiatric Status Rating Scales |
| Symptoms of Posttraumatic Stress after Intensive Care Delirium. | Svenningsen H, Egerod I, Christensen D, Tønnesen EK, Frydenberg M, Videbech P | BioMed research international | 2015 | |
| Constipation is independently associated with delirium in critically ill ventilated patients. | Smonig R, Wallenhorst T, Bouju P, Letheulle J, Le Tulzo Y, Tadié JM, Gacouin A | Intensive care medicine | 2015 | |
| Surgery plus anesthesia induces loss of attention in mice. | Ren Q, Peng M, Dong Y, Zhang Y, Chen M, Yin N, Marcantonio ER, Xie Z | Frontiers in cellular neuroscience | 2015 | |
| The diurnal profile of melatonin during delirium in elderly patients--preliminary results. | Piotrowicz K, Klich-Rączka A, Pac A, Zdzienicka A, Grodzicki T | Experimental gerontology | 2015 | |
| Cognitive and functional status predictors of delirium and delirium severity after coronary artery bypass graft surgery: an interim analysis of the Neuropsychiatric Outcomes After Heart Surgery study. | Oldham MA, Hawkins KA, Yuh DD, Dewar ML, Darr UM, Lysyy T, Lee HB | International psychogeriatrics / IPA | 2015 | |
| Preoperative physical activity in relation to postoperative delirium in elective cardiac surgery patients. | Ogawa M, Izawa KP, Kitamura A, Ono R, Satomi-Kobayashi S, Sakai Y, Okita Y | International journal of cardiology | 2015 | |
| Predicting delirium: a review of risk-stratification models. | Newman MW, O'Dwyer LC, Rosenthal L | General hospital psychiatry | 2015 | |
| Long-Term Outcomes of Older Adults with and Without Delirium Immediately After Recovery from General Anesthesia for Surgery. | Neufeld KJ, Leoutsakos JM, Oh E, Sieber FE, Chandra A, Ghosh A, Schretlen DJ, Needham DM | The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry | 2015 | |
| Clinical impact of delirium and antipsychotic therapy: 10-Year experience from a referral coronary care unit. | Naksuk N, Thongprayoon C, Park JY, Sharma S, Gaba P, Rosenbaum AN, Peeraphatdit T, Hu TY, Bell MR, Herasevich V, Brady PA, Kapa S, Asirvatham SJ | European heart journal. Acute cardiovascular care | 2015 | |
| Hematoma Locations Predicting Delirium Symptoms After Intracerebral Hemorrhage. | Naidech AM, Polnaszek KL, Berman MD, Voss JL | Neurocritical care | 2015 | |
| The effects of a tailored intensive care unit delirium prevention protocol: A randomized controlled trial. | Moon KJ, Lee SM | International journal of nursing studies | 2015 |
Cognition, Delirium, prevention & control, Humans, Intensive Care Units, Single-Blind Method |
| Months backward test: A review of its use in clinical studies. | Meagher J, Leonard M, Donoghue L, O'Regan N, Timmons S, Exton C, Cullen W, Dunne C, Adamis D, Maclullich AJ, Meagher D | World journal of psychiatry | 2015 | |
| An exercise program with patient's involvement and family support can modify the cognitive and affective trajectory of acutely hospitalized older medical patients: a pilot study. | Martínez-Velilla N, Garrués-Irisarri M, Ibañez-Beroiz B, Gil-Cabañas J, Richarte-García A, Idoate-Saralegui F, de Paz PC, Cambra K | Aging clinical and experimental research | 2015 | |
| Comprehensive Geriatric Assessment is a useful predictive tool for postoperative delirium after gastrointestinal surgery in old-old adults. | Maekawa Y, Sugimoto K, Yamasaki M, Takeya Y, Yamamoto K, Ohishi M, Ogihara T, Shintani A, Doki Y, Mori M, Rakugi H | Geriatrics & gerontology international | 2016 | |
| Acute traumatic and depressive symptoms in family members of hospitalized individuals with delirium. | Lloyd RB, Rosenthal LJ | International journal of psychiatry in medicine | 2015 | |
| Influence of Ketamine on Early Postoperative Cognitive Function After Orthopedic Surgery in Elderly Patients. | Lee KH, Kim JY, Kim JW, Park JS, Lee KW, Jeon SY | Anesthesiology and pain medicine | 2015 | |
| Detection of Delirium in Hospitalized Older General Medicine Patients: A Comparison of the 3D-CAM and CAM-ICU. | Kuczmarska A, Ngo LH, Guess J, O'Connor MA, Branford-White L, Palihnich K, Gallagher J, Marcantonio ER | Journal of general internal medicine | 2016 | |
| Antipsychotic medications for the treatment of delirium: a systematic review and meta-analysis of randomised controlled trials. | Kishi T, Hirota T, Matsunaga S, Iwata N | Journal of neurology, neurosurgery, and psychiatry | 2015 | |
| Differential Associations Between Delirium and Mortality According to Delirium Subtype and Age: A Prospective Cohort Study. | Kim SY, Kim SW, Kim JM, Shin IS, Bae KY, Shim HJ, Bae WK, Cho SH, Chung IJ, Yoon JS | Psychosomatic medicine | 2015 | |
| Development of Delirium in the Intensive Care Unit in Patients after Endovascular Aortic Repair: A Retrospective Evaluation of the Prevalence and Risk Factors. | Kawatani Y, Nakamura Y, Hayashi Y, Taneichi T, Ito Y, Kurobe H, Suda Y, Hori T | Critical care research and practice | 2015 | |
| Non-pharmacological interventions for sleep promotion in the intensive care unit. | Hu RF, Jiang XY, Chen J, Zeng Z, Chen XY, Li Y, Huining X, Evans DJ | The Cochrane database of systematic reviews | 2015 | |
| Clinical deterioration in older adults with delirium during early hospitalisation: a prospective cohort study. | Hsieh SJ, Madahar P, Hope AA, Zapata J, Gong MN | BMJ open | 2015 | |
| Human herpesvirus 6B reactivation and delirium are frequent and associated events after cord blood transplantation. | Hill JA, Boeckh M, Leisenring WM, Xie H, Adler AL, Huang ML, Fann JR, Delaney C, Zerr DM | Bone marrow transplantation | 2015 | |
| Risk factors for delirium after on-pump cardiac surgery: a systematic review. | Gosselt AN, Slooter AJ, Boere PR, Zaal IJ | Critical care (London, England) | 2015 | |
| Effect of Delirium and Other Major Complications on Outcomes After Elective Surgery in Older Adults. | Gleason LJ, Schmitt EM, Kosar CM, Tabloski P, Saczynski JS, Robinson T, Cooper Z, Rogers SO, Jones RN, Marcantonio ER, Inouye SK | JAMA surgery | 2015 | |
| Intraoperative Electroencephalogram Suppression Predicts Postoperative Delirium. | Fritz BA, Kalarickal PL, Maybrier HR, Muench MR, Dearth D, Chen Y, Escallier KE, Ben Abdallah A, Lin N, Avidan MS | Anesthesia and analgesia | 2016 | |
| Preliminary development of an ultrabrief two-item bedside test for delirium. | Fick DM, Inouye SK, Guess J, Ngo LH, Jones RN, Saczynski JS, Marcantonio ER | Journal of hospital medicine | 2015 | |
| The Frequency, Characteristics, and Outcomes Among Cancer Patients With Delirium Admitted to an Acute Palliative Care Unit. | de la Cruz M, Ransing V, Yennu S, Wu J, Liu D, Reddy A, Delgado-Guay M, Bruera E | The oncologist | 2015 | |
| Partial and No Recovery from Delirium in Older Hospitalized Adults: Frequency and Baseline Risk Factors. | Cole MG, Bailey R, Bonnycastle M, McCusker J, Fung S, Ciampi A, Belzile E, Bai C | Journal of the American Geriatrics Society | 2015 |
Activities of Daily Living, Aged, Aged, 80 and over, Delirium, physiopathology, Dementia, complications, Female, Follow-Up Studies, Humans, Inpatients, Intelligence Tests, Male, Prognosis, Risk Factors |
| Short-Form Mini Nutritional Assessment as a useful method of predicting the development of postoperative delirium in elderly patients undergoing orthopedic surgery. | Chu CS, Liang CK, Chou MY, Lin YT, Hsu CJ, Chou PH, Chu CL | General hospital psychiatry | 2016 | |
| Under-detection of delirium and impact of neurocognitive deficits on in-hospital mortality among acute geriatric and medical wards. | Bellelli G, Nobili A, Annoni G, Morandi A, Djade CD, Meagher DJ, Maclullich AM, Davis D, Mazzone A, Tettamanti M, Mannucci PM, | European journal of internal medicine | 2015 | |
| Timing Is Critical in Determining the Association Between Delirium and S100 Calcium-Binding Protein B. | Beishuizen SJ, Scholtens RM, Vellekoop AE, Vrouenraets BC, Westhoff D, van de Beek D, de Rooij SE, van Munster BC | Journal of the American Geriatrics Society | 2015 | |
| Delirium monitoring and patient outcomes in a general intensive care unit. | Andrews L, Silva SG, Kaplan S, Zimbro K | American journal of critical care : an official publication, American Association of Critical-Care Nurses | 2015 |
Aged, Aged, 80 and over, Delirium, diagnosis, Female, Humans, Intensive Care, methods, Intensive Care Units, Length of Stay, statistics & numerical data, Male, Neuropsychological Tests, statistics & numerical data, Nursing Assessment, methods, Outcome and Process Assessment (Health Care), statistics & numerical data, Questionnaires, Respiration, Artificial, statistics & numerical data, Retrospective Studies |
| Evaluating attention in delirium: A comparison of bedside tests of attention. | Adamis D, Meagher D, Murray O, O'Neill D, O'Mahony E, Mulligan O, McCarthy G | Geriatrics & gerontology international | 2016 | |
| Prevention of delirium (POD) for older people in hospital: study protocol for a randomised controlled feasibility trial. | Young J, Cheater F, Collinson M, Fletcher M, Forster A, Godfrey M, Green J, Anwar S, Hartley S, Hulme C, Inouye SK, Meads D, Santorelli G, Siddiqi N, Smith J, Teale E, Farrin AJ | Trials | 2015 | |
| Intraoperative hypotension and delirium after on-pump cardiac surgery. | Wesselink EM, Kappen TH, van Klei WA, Dieleman JM, van Dijk D, Slooter AJ | British journal of anaesthesia | 2015 |
Adult, Aged, Aged, 80 and over, Antiemetics, administration & dosage, Cardiac Surgical Procedures, Cohort Studies, Delirium, epidemiology, Dexamethasone, administration & dosage, Female, Humans, Hypotension, epidemiology, Intraoperative Complications, epidemiology, Male, Middle Aged, Postoperative Complications, epidemiology, Young Adult |
| Cytokines and Postoperative Delirium in Older Patients Undergoing Major Elective Surgery. | Vasunilashorn SM, Ngo L, Inouye SK, Libermann TA, Jones RN, Alsop DC, Guess J, Jastrzebski S, McElhaney JE, Kuchel GA, Marcantonio ER | The journals of gerontology. Series A, Biological sciences and medical sciences | 2015 | |
| Is preoperative state anxiety a risk factor for postoperative delirium among elderly hip fracture patients? | Van Grootven B, Detroyer E, Devriendt E, Sermon A, Deschodt M, Flamaing J, Dubois C, Milisen K | Geriatrics & gerontology international | 2016 | |
| Prevalence, course and factors associated with delirium in elderly patients with advanced cancer: a longitudinal observational study. | Uchida M, Okuyama T, Ito Y, Nakaguchi T, Miyazaki M, Sakamoto M, Kamiya T, Sato S, Takeyama H, Joh T, Meagher D, Akechi T | Japanese journal of clinical oncology | 2015 | |
| Incidence and risk factors of postoperative delirium in elderly patients who underwent laparoscopic surgery for colorectal cancer. | Tei M, Wakasugi M, Kishi K, Tanemura M, Akamatsu H | International journal of colorectal disease | 2016 | |
| Factors predicting perioperative delirium and acute exacerbation of behavioral and psychological symptoms of dementia based on admission data in elderly patients with proximal femoral fracture: A retrospective study. | Tanaka T | Geriatrics & gerontology international | 2016 | |
| Impact of surgical approach on postoperative delirium in elderly patients undergoing gastrectomy: laparoscopic versus open approaches. | Shin YH, Kim DK, Jeong HJ | Korean journal of anesthesiology | 2015 | |
| Frequency and Outcome of Neuroleptic Rotation in the Management of Delirium in Patients with Advanced Cancer. | Shin SH, Hui D, Chisholm G, Kang JH, Allo J, Williams J, Bruera E | Cancer research and treatment : official journal of Korean Cancer Association | 2015 | |
| Prognostic Significance of Postoperative Subsyndromal Delirium. | Shim J, DePalma G, Sands LP, Leung JM | Psychosomatics | 2015 | |
| Relationship between cobalamin deficiency and delirium in elderly patients undergoing cardiac surgery. | Sevuk U, Baysal E, Ay N, Altas Y, Altindag R, Yaylak B, Alp V, Demirtas E | Neuropsychiatric disease and treatment | 2015 | |
| Performance of the Delirium Rating Scale-Revised-98 Against Different Delirium Diagnostic Criteria in a Population With a High Prevalence of Dementia. | Sepulveda E, Franco JG, Trzepacz PT, Gaviria AM, Viñuelas E, Palma J, Ferré G, Grau I, Vilella E | Psychosomatics | 2015 | |
| Prognostic value and risk factors of delirium in emergency patients with decompensated heart failure. | Rizzi MA, Torres Bonafonte OH, Alquezar A, Herrera Mateo S, Piñera P, Puig M, Benito S, Ruiz D | Journal of the American Medical Directors Association | 2015 | |
| Risk Factors and Outcomes for Postoperative Delirium after Major Surgery in Elderly Patients. | Raats JW, van Eijsden WA, Crolla RM, Steyerberg EW, van der Laan L | PloS one | 2015 | |
| The Language of Delirium: Keywords for Identifying Delirium from Medical Records. | Puelle MR, Kosar CM, Xu G, Schmitt E, Jones RN, Marcantonio ER, Cooper Z, Inouye SK, Saczynski JS | Journal of gerontological nursing | 2015 |
Aged, Aged, 80 and over, Cohort Studies, Delirium, diagnosis, Electronic Health Records, Female, Humans, Male, Terminology as Topic |
| Delirium is a robust predictor of morbidity and mortality among critically ill patients treated in the cardiac intensive care unit. | Pauley E, Lishmanov A, Schumann S, Gala GJ, van Diepen S, Katz JN | American heart journal | 2015 |
APACHE, Acute Kidney Injury, epidemiology, Age Factors, Aged, Cohort Studies, Comorbidity, Critical Illness, Delirium, epidemiology, Female, Heart Arrest, epidemiology, Heart Diseases, epidemiology, Heart Valve Diseases, epidemiology, Humans, Intensive Care Units, Length of Stay, Linear Models, Logistic Models, Male, Middle Aged, Multivariate Analysis, Myocardial Infarction, epidemiology, North Carolina, epidemiology, Prevalence, Prognosis, Respiratory Insufficiency, epidemiology, Sepsis, epidemiology, Severity of Illness Index |
| Return to work six months after burn: A prospective study at the Helsinki Burn Center. | Palmu R, Partonen T, Suominen K, Vuola J, Isometsä E | Burns : journal of the International Society for Burn Injuries | 2015 | |
| Delirium, how does it end? Mortality as an outcome in older medical inpatients. | Muresan ML, Adamis D, Murray O, O'Mahony E, McCarthy G | International journal of geriatric psychiatry | 2015 | |
| Delirium superimposed on dementia: A quantitative and qualitative evaluation of informal caregivers and health care staff experience. | Morandi A, Lucchi E, Turco R, Morghen S, Guerini F, Santi R, Gentile S, Meagher D, Voyer P, Fick DM, Schmitt EM, Inouye SK, Trabucchi M, Bellelli G | Journal of psychosomatic research | 2015 |
Caregivers, psychology, Cohort Studies, Delirium, nursing, Dementia, nursing, Female, Humans, Male, Middle Aged, Patient Care Team, standards, Prospective Studies, Surveys and Questionnaires |
| Delirium superimposed on dementia: A quantitative and qualitative evaluation of patient experience. | Morandi A, Lucchi E, Turco R, Morghen S, Guerini F, Santi R, Gentile S, Meagher D, Voyer P, Fick D, Schmitt EM, Inouye SK, Trabucchi M, Bellelli G | Journal of psychosomatic research | 2015 | |
| Delirium and Circadian Rhythm of Melatonin During Weaning From Mechanical Ventilation: An Ancillary Study of a Weaning Trial. | Mekontso Dessap A, Roche-Campo F, Launay JM, Charles-Nelson A, Katsahian S, Brun-Buisson C, Brochard L | Chest | 2015 |
Aged, Ancillary Services, Hospital, Circadian Rhythm, Delirium, etiology, Female, Follow-Up Studies, Humans, Intensive Care Units, Male, Melatonin, analogs & derivatives, Middle Aged, Respiration, Artificial, Time Factors, Ventilator Weaning, methods |
| Chemotherapeutic drugs that penetrate the blood-brain barrier affect the development of hyperactive delirium in cancer patients. | Matsuoka H, Yoshiuchi K, Koyama A, Otsuka M, Nakagawa K | Palliative & supportive care | 2015 | |
| Patient factors associated with 30-day morbidity, mortality, and length of stay after surgery for subdural hematoma: a study of the American College of Surgeons National Surgical Quality Improvement Program. | Lukasiewicz AM, Grant RA, Basques BA, Webb ML, Samuel AM, Grauer JN | Journal of neurosurgery | 2015 | |
| Preoperative Sleep Disruption and Postoperative Delirium. | Leung JM, Sands LP, Newman S, Meckler G, Xie Y, Gay C, Lee K | Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine | 2015 | |
| Anesthesiologic regimen and intraoperative delirium in deep brain stimulation surgery for Parkinson's disease. | Lange M, Zech N, Seemann M, Janzen A, Halbing D, Zeman F, Doenitz C, Rothenfusser E, Hansen E, Brawanski A, Schlaier J | Journal of the neurological sciences | 2015 | |
| Predicting outcome in older hospital patients with delirium: a systematic literature review. | Jackson TA, Wilson D, Richardson S, Lord JM | International journal of geriatric psychiatry | 2016 | |
| Enhancing Cognitive Aging: Clinical Highlights of a Report From the Institute of Medicine. | Inouye SK | Annals of internal medicine | 2015 | |
| Risk factors associated with postoperative delirium after surgery for oral cancer. | Hasegawa T, Saito I, Takeda D, Iwata E, Yonezawa N, Kakei Y, Sakakibara A, Akashi M, Minamikawa T, Komori T | Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery | 2015 | |
| The Diagnostic Performance of the Richmond Agitation Sedation Scale for Detecting Delirium in Older Emergency Department Patients. | Han JH, Vasilevskis EE, Schnelle JF, Shintani A, Dittus RS, Wilson A, Ely EW | Academic emergency medicine : official journal of the Society for Academic Emergency Medicine | 2015 |
Age Factors, Aged, Aged, 80 and over, Clinical Protocols, Consciousness, Delirium, diagnosis, Emergency Service, Hospital, organization & administration, Female, Humans, Male, Prospective Studies, Reproducibility of Results, Sensitivity and Specificity |
| Risk factors and clinical aspects of delirium in elderly hospitalized patients in Iran. | Foroughan M, Delbari A, Said SE, AkbariKamrani AA, Rashedi V, Zandi T | Aging clinical and experimental research | 2016 | |
| The interface between delirium and dementia in elderly adults. | Fong TG, Davis D, Growdon ME, Albuquerque A, Inouye SK | The Lancet. Neurology | 2015 | |
| Predictors of Long-Term Mortality in Oldest Old Patients (90+) Hospitalized to Medical Wards via the Emergency Department: The SAFES Cohort. | de Boissieu P, Mahmoudi R, Hentzien M, Toquet S, Novella JL, Blanchard F, Jolly D, Dramé M | The journal of nutrition, health & aging | 2015 | |
| Exogenous Melatonin for Delirium Prevention: a Meta-analysis of Randomized Controlled Trials. | Chen S, Shi L, Liang F, Xu L, Desislava D, Wu Q, Zhang J | Molecular neurobiology | 2015 | |
| Efficacy of Non-Pharmacological Interventions to Prevent and Treat Delirium in Older Patients: A Systematic Overview. The SENATOR project ONTOP Series. | Abraha I, Trotta F, Rimland JM, Cruz-Jentoft A, Lozano-Montoya I, Soiza RL, Pierini V, Dessì Fulgheri P, Lattanzio F, O'Mahony D, Cherubini A | PloS one | 2015 | |
| Effect of dexmedetomidine on preventing agitation and delirium after microvascular free flap surgery: a randomized, double-blind, control study. | Yang X, Li Z, Gao C, Liu R | Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons | 2015 | |
| Intraoperative tight glucose control using hyperinsulinemic normoglycemia increases delirium after cardiac surgery. | Saager L, Duncan AE, Yared JP, Hesler BD, You J, Deogaonkar A, Sessler DI, Kurz A | Anesthesiology | 2015 |
Aged, Aged, 80 and over, Blood Glucose, analysis, Cardiac Surgical Procedures, adverse effects, Confusion, psychology, Delirium, chemically induced, Double-Blind Method, Female, Glucose Clamp Technique, Humans, Hyperinsulinism, blood, Intraoperative Care, adverse effects, Male, Middle Aged, Neuropsychological Tests, Postoperative Complications, chemically induced |
| Association between pre-hospital vitamin D status and hospital-acquired new-onset delirium. | Quraishi SA, Litonjua AA, Elias KM, Gibbons FK, Giovannucci E, Camargo CA, Christopher KB | The British journal of nutrition | 2015 | |
| Effect Estimation of an Innovative Nursing Intervention to Improve Delirium among Home-Dwelling Older Adults: A Randomized Controlled Pilot Trial. | Verloo H, Goulet C, Morin D, von Gunten A | Dementia and geriatric cognitive disorders extra | 2015 | |
| Identifying phenomenological differences and recovery of cognitive and non-cognitive symptomatology among delirium superimposed upon dementia patients (DsD) versus those without dementia (DaD) in an acute geriatric care setting. | Chong E, Tay L, Chong MS | International psychogeriatrics / IPA | 2015 | |
| Health economic implications of perioperative delirium in older patients after surgery for a fragility hip fracture. | Zywiel MG, Hurley RT, Perruccio AV, Hancock-Howard RL, Coyte PC, Rampersaud YR | The Journal of bone and joint surgery. American volume | 2015 |
Aged, Aged, 80 and over, Case-Control Studies, Costs and Cost Analysis, Delirium, economics, Female, Fractures, Spontaneous, economics, Hip Fractures, economics, Humans, Length of Stay, economics, Male, Perioperative Care, economics, Postoperative Complications, economics, Propensity Score, Prospective Studies |
| Anticholinergic Medication Use and Transition to Delirium in Critically Ill Patients: A Prospective Cohort Study. | Wolters AE, Zaal IJ, Veldhuijzen DS, Cremer OL, Devlin JW, van Dijk D, Slooter AJ | Critical care medicine | 2015 |
Academic Medical Centers, Age Factors, Aged, Cholinergic Antagonists, adverse effects, Comorbidity, Critical Illness, Delirium, chemically induced, Female, Health Status, Humans, Intensive Care Units, Male, Markov Chains, Middle Aged, Prospective Studies, Risk Factors |
| Preoperative risk factors of postoperative delirium after transurethral prostatectomy for benign prostatic hyperplasia. | Tai S, Xu L, Zhang L, Fan S, Liang C | International journal of clinical and experimental medicine | 2015 | |
| Dexmedetomidine versus Propofol Sedation Reduces Delirium after Cardiac Surgery: A Randomized Controlled Trial. | Djaiani G, Silverton N, Fedorko L, Carroll J, Styra R, Rao V, Katznelson R | Anesthesiology | 2016 | |
| An Innovative Approach to Improving the Accuracy of Delirium Assessments Using the Confusion Assessment Method for the Intensive Care Unit. | DiLibero J, O'Donoghue SC, DeSanto-Madeya S, Felix J, Ninobla A, Woods A | Dimensions of critical care nursing : DCCN | 2016 | |
| Moderate dose melatonin for the abatement and treatment of delirium in elderly general medical inpatients: study protocol of a placebo controlled, randomised, double blind trial. | Clayton-Chubb DI, Lange PW | BMC geriatrics | 2016 | |
| Underdiagnosis of delirium on admission and prediction of patients who will develop delirium during their inpatient stay: a pilot study. | Chin YC, Koh GC, Tay YK, Tan CH, Merchant RA | Singapore medical journal | 2016 | |
| Neural substrates of vulnerability to postsurgical delirium as revealed by presurgical diffusion MRI. | Cavallari M, Dai W, Guttmann CR, Meier DS, Ngo LH, Hshieh TT, Callahan AE, Fong TG, Schmitt E, Dickerson BC, Press DZ, Marcantonio ER, Jones RN, Inouye SK, Alsop DC, | Brain : a journal of neurology | 2016 | |
| Educating Family Caregivers for Older Adults About Delirium: A Systematic Review. | Bull MJ, Boaz L, Jermé M | Worldviews on evidence-based nursing / Sigma Theta Tau International, Honor Society of Nursing | 2016 | |
| Delirium: assessment and treatment of patients with cancer. PART 2. | Brown M, Hardy K | British journal of nursing (Mark Allen Publishing) | 2016 | |
| The Impact of Delirium After Cardiac Surgical Procedures on Postoperative Resource Use. | Brown CH, Laflam A, Max L, Lymar D, Neufeld KJ, Tian J, Shah AS, Whitman GJ, Hogue CW | The Annals of thoracic surgery | 2016 | |
| Sleep and delirium in unsedated patients in the intensive care unit. | Boesen HC, Andersen JH, Bendtsen AO, Jennum PJ | Acta anaesthesiologica Scandinavica | 2016 | |
| Delirium in cardiac ICU patients. | Bamalwa M, Mahmood SN, Praharaj SK | Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists | 2016 | |
| Under Pressure: Reduced Cerebral Perfusion as a Risk Factor for Postoperative Delirium in Lung Transplant Recipients. | Anderson BJ, Diamond JM | Annals of the American Thoracic Society | 2016 | |
| Serum protein S100 as marker of postoperative delirium after off-pump coronary artery bypass surgery: secondary analysis of two prospective randomized controlled trials. | Al Tmimi L, Van de Velde M, Meyns B, Meuris B, Sergeant P, Milisen K, Pottel H, Poesen K, Rex S | Clinical chemistry and laboratory medicine | 2016 | |
| Psychometric evaluation of the DMSS-4 in a cohort of elderly post-operative hip fracture patients with delirium. | Adamis D, Scholtens RM, de Jonghe A, van Munster BC, de Rooij SE, Meagher DJ | International psychogeriatrics / IPA | 2016 | |
| Incidence, Predictive Factors, and Effect of Delirium After Transcatheter Aortic Valve Replacement. | Abawi M, Nijhoff F, Agostoni P, Emmelot-Vonk MH, de Vries R, Doevendans PA, Stella PR | JACC. Cardiovascular interventions | 2016 | |
| Higher serum interieukin-6 is a strong postoperative predictor of delirium after isolated coronary artery bypass graft surgery | Sun, L. Ding, S. Feng, X. Wu, F. Su, P. Shen, Y. Zhao, H. Wu, Y. | Circulation | 2014 |
interleukin 6 |