What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Preliminary Study of Serum Biomarkers Associated With Delirium After Major Cardiac Surgery
- Authors
- McKay, T. B. Rhee, J. Colon, K. Adelsberger, K. Turco, I. Mueller, A. Qu, J. Akeju, O.
- Year
- 2021
- Journal
- J Cardiothorac Vasc Anesth
- Abstract
OBJECTIVES: The objective of this study was to identify novel serum biomarkers specific to postoperative delirium after major cardiac surgery to provide insight into the pathologic processes involved in delirium and its sequelae. DESIGN: Nested, case-control study. SETTING: Cardiac surgical intensive care unit in a single-site hospital setting. PARTICIPANTS: The study comprised 24 older adults (aged >60 years) undergoing major cardiac surgery with cardiopulmonary bypass. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: The primary outcome was a positive screen for delirium from postoperative days one through three based on criteria included in the long form of the Confusion Assessment Method. A multiplexed proteomic approach was applied using proximity extension assays to identify and quantify proteins found in serum collected on the day of surgery and postoperative day one in delirious and nondelirious patient cohorts. An increase in serum fibroblast growth factor (FGF)-21 levels was identified in the delirious cohort from a presurgery baseline of (mean ± standard deviation) 5.0 ± 1.1 log2 abundance (95% confidence interval [CI], 4.3-5.7) to 6.7 ± 1.6 log2 abundance (95% CI, 5.7-7.7; p = 0.01) postsurgery. A similar increase was identified in FGF-23 from a presurgery baseline of 1.7 ± 1.3 log2 abundance (95% CI, 0.8-2.5) to 3.4 ± 2.2 log2 abundance (95% CI, 2.0-4.8; p = 0.06) postsurgery. An increase in interleukin-6 serum levels also was identified in the delirious cohort from a presurgery baseline of 3.8 ± 1.1 log2 abundance (95% CI, 3.1-4.5) to 8.7 ± 1.9 log2 abundance (95% CI, 7.5-9.9; p < 0.0001) postsurgery. However, the increase in interleukin-6 serum levels of the nondelirious cohort also met the study’s threshold for statistical significance (p < 0.0001). Finally, an increase in monocyte chemotactic protein-3 serum levels was identified in the delirious cohort from a presurgery baseline of 4.1 ± 0.9 log2 abundance (95% CI, 3.6-4.7) to 6.1 ± 2.0 log2 abundance (95% CI, 4.8-7; p = 0.009) postsurgery. CONCLUSIONS: FGF-21, FGF-23, interleukin-6, and monocyte chemotactic protein-3 serum levels were increased postoperatively in patients who developed delirium after major cardiac surgery. This study identified two members of the FGF family as potential putative systemic biomarkers for postoperative delirium after cardiac surgery, suggesting a possible role for metabolic recovery in the pathophysiologic mechanisms underlying neurocognitive dysfunction.
- PMID
- Keywords
Fgf
cardiac surgery
cardiopulmonary bypass
cognition
delirium
fibroblast growth factor
inflammation
metabolism
neurodegeneration
- Page(s)
- Volume
- Issue
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| Development of Delirium in the Intensive Care Unit in Patients after Endovascular Aortic Repair: A Retrospective Evaluation of the Prevalence and Risk Factors. | Kawatani Y, Nakamura Y, Hayashi Y, Taneichi T, Ito Y, Kurobe H, Suda Y, Hori T | Critical care research and practice | 2015 | |
| Non-pharmacological interventions for sleep promotion in the intensive care unit. | Hu RF, Jiang XY, Chen J, Zeng Z, Chen XY, Li Y, Huining X, Evans DJ | The Cochrane database of systematic reviews | 2015 | |
| Clinical deterioration in older adults with delirium during early hospitalisation: a prospective cohort study. | Hsieh SJ, Madahar P, Hope AA, Zapata J, Gong MN | BMJ open | 2015 | |
| Human herpesvirus 6B reactivation and delirium are frequent and associated events after cord blood transplantation. | Hill JA, Boeckh M, Leisenring WM, Xie H, Adler AL, Huang ML, Fann JR, Delaney C, Zerr DM | Bone marrow transplantation | 2015 | |
| Risk factors for delirium after on-pump cardiac surgery: a systematic review. | Gosselt AN, Slooter AJ, Boere PR, Zaal IJ | Critical care (London, England) | 2015 | |
| Effect of Delirium and Other Major Complications on Outcomes After Elective Surgery in Older Adults. | Gleason LJ, Schmitt EM, Kosar CM, Tabloski P, Saczynski JS, Robinson T, Cooper Z, Rogers SO, Jones RN, Marcantonio ER, Inouye SK | JAMA surgery | 2015 | |
| Intraoperative Electroencephalogram Suppression Predicts Postoperative Delirium. | Fritz BA, Kalarickal PL, Maybrier HR, Muench MR, Dearth D, Chen Y, Escallier KE, Ben Abdallah A, Lin N, Avidan MS | Anesthesia and analgesia | 2016 | |
| Preliminary development of an ultrabrief two-item bedside test for delirium. | Fick DM, Inouye SK, Guess J, Ngo LH, Jones RN, Saczynski JS, Marcantonio ER | Journal of hospital medicine | 2015 | |
| The Frequency, Characteristics, and Outcomes Among Cancer Patients With Delirium Admitted to an Acute Palliative Care Unit. | de la Cruz M, Ransing V, Yennu S, Wu J, Liu D, Reddy A, Delgado-Guay M, Bruera E | The oncologist | 2015 | |
| Partial and No Recovery from Delirium in Older Hospitalized Adults: Frequency and Baseline Risk Factors. | Cole MG, Bailey R, Bonnycastle M, McCusker J, Fung S, Ciampi A, Belzile E, Bai C | Journal of the American Geriatrics Society | 2015 |
Activities of Daily Living, Aged, Aged, 80 and over, Delirium, physiopathology, Dementia, complications, Female, Follow-Up Studies, Humans, Inpatients, Intelligence Tests, Male, Prognosis, Risk Factors |
| Short-Form Mini Nutritional Assessment as a useful method of predicting the development of postoperative delirium in elderly patients undergoing orthopedic surgery. | Chu CS, Liang CK, Chou MY, Lin YT, Hsu CJ, Chou PH, Chu CL | General hospital psychiatry | 2016 | |
| Under-detection of delirium and impact of neurocognitive deficits on in-hospital mortality among acute geriatric and medical wards. | Bellelli G, Nobili A, Annoni G, Morandi A, Djade CD, Meagher DJ, Maclullich AM, Davis D, Mazzone A, Tettamanti M, Mannucci PM, | European journal of internal medicine | 2015 | |
| Timing Is Critical in Determining the Association Between Delirium and S100 Calcium-Binding Protein B. | Beishuizen SJ, Scholtens RM, Vellekoop AE, Vrouenraets BC, Westhoff D, van de Beek D, de Rooij SE, van Munster BC | Journal of the American Geriatrics Society | 2015 | |
| Delirium monitoring and patient outcomes in a general intensive care unit. | Andrews L, Silva SG, Kaplan S, Zimbro K | American journal of critical care : an official publication, American Association of Critical-Care Nurses | 2015 |
Aged, Aged, 80 and over, Delirium, diagnosis, Female, Humans, Intensive Care, methods, Intensive Care Units, Length of Stay, statistics & numerical data, Male, Neuropsychological Tests, statistics & numerical data, Nursing Assessment, methods, Outcome and Process Assessment (Health Care), statistics & numerical data, Questionnaires, Respiration, Artificial, statistics & numerical data, Retrospective Studies |
| Evaluating attention in delirium: A comparison of bedside tests of attention. | Adamis D, Meagher D, Murray O, O'Neill D, O'Mahony E, Mulligan O, McCarthy G | Geriatrics & gerontology international | 2016 | |
| Prevention of delirium (POD) for older people in hospital: study protocol for a randomised controlled feasibility trial. | Young J, Cheater F, Collinson M, Fletcher M, Forster A, Godfrey M, Green J, Anwar S, Hartley S, Hulme C, Inouye SK, Meads D, Santorelli G, Siddiqi N, Smith J, Teale E, Farrin AJ | Trials | 2015 | |
| Intraoperative hypotension and delirium after on-pump cardiac surgery. | Wesselink EM, Kappen TH, van Klei WA, Dieleman JM, van Dijk D, Slooter AJ | British journal of anaesthesia | 2015 |
Adult, Aged, Aged, 80 and over, Antiemetics, administration & dosage, Cardiac Surgical Procedures, Cohort Studies, Delirium, epidemiology, Dexamethasone, administration & dosage, Female, Humans, Hypotension, epidemiology, Intraoperative Complications, epidemiology, Male, Middle Aged, Postoperative Complications, epidemiology, Young Adult |
| Cytokines and Postoperative Delirium in Older Patients Undergoing Major Elective Surgery. | Vasunilashorn SM, Ngo L, Inouye SK, Libermann TA, Jones RN, Alsop DC, Guess J, Jastrzebski S, McElhaney JE, Kuchel GA, Marcantonio ER | The journals of gerontology. Series A, Biological sciences and medical sciences | 2015 | |
| Is preoperative state anxiety a risk factor for postoperative delirium among elderly hip fracture patients? | Van Grootven B, Detroyer E, Devriendt E, Sermon A, Deschodt M, Flamaing J, Dubois C, Milisen K | Geriatrics & gerontology international | 2016 | |
| Prevalence, course and factors associated with delirium in elderly patients with advanced cancer: a longitudinal observational study. | Uchida M, Okuyama T, Ito Y, Nakaguchi T, Miyazaki M, Sakamoto M, Kamiya T, Sato S, Takeyama H, Joh T, Meagher D, Akechi T | Japanese journal of clinical oncology | 2015 | |
| Incidence and risk factors of postoperative delirium in elderly patients who underwent laparoscopic surgery for colorectal cancer. | Tei M, Wakasugi M, Kishi K, Tanemura M, Akamatsu H | International journal of colorectal disease | 2016 | |
| Factors predicting perioperative delirium and acute exacerbation of behavioral and psychological symptoms of dementia based on admission data in elderly patients with proximal femoral fracture: A retrospective study. | Tanaka T | Geriatrics & gerontology international | 2016 | |
| Impact of surgical approach on postoperative delirium in elderly patients undergoing gastrectomy: laparoscopic versus open approaches. | Shin YH, Kim DK, Jeong HJ | Korean journal of anesthesiology | 2015 | |
| Frequency and Outcome of Neuroleptic Rotation in the Management of Delirium in Patients with Advanced Cancer. | Shin SH, Hui D, Chisholm G, Kang JH, Allo J, Williams J, Bruera E | Cancer research and treatment : official journal of Korean Cancer Association | 2015 | |
| Prognostic Significance of Postoperative Subsyndromal Delirium. | Shim J, DePalma G, Sands LP, Leung JM | Psychosomatics | 2015 | |
| Relationship between cobalamin deficiency and delirium in elderly patients undergoing cardiac surgery. | Sevuk U, Baysal E, Ay N, Altas Y, Altindag R, Yaylak B, Alp V, Demirtas E | Neuropsychiatric disease and treatment | 2015 | |
| Performance of the Delirium Rating Scale-Revised-98 Against Different Delirium Diagnostic Criteria in a Population With a High Prevalence of Dementia. | Sepulveda E, Franco JG, Trzepacz PT, Gaviria AM, Viñuelas E, Palma J, Ferré G, Grau I, Vilella E | Psychosomatics | 2015 | |
| Prognostic value and risk factors of delirium in emergency patients with decompensated heart failure. | Rizzi MA, Torres Bonafonte OH, Alquezar A, Herrera Mateo S, Piñera P, Puig M, Benito S, Ruiz D | Journal of the American Medical Directors Association | 2015 | |
| Risk Factors and Outcomes for Postoperative Delirium after Major Surgery in Elderly Patients. | Raats JW, van Eijsden WA, Crolla RM, Steyerberg EW, van der Laan L | PloS one | 2015 | |
| The Language of Delirium: Keywords for Identifying Delirium from Medical Records. | Puelle MR, Kosar CM, Xu G, Schmitt E, Jones RN, Marcantonio ER, Cooper Z, Inouye SK, Saczynski JS | Journal of gerontological nursing | 2015 |
Aged, Aged, 80 and over, Cohort Studies, Delirium, diagnosis, Electronic Health Records, Female, Humans, Male, Terminology as Topic |
| Delirium is a robust predictor of morbidity and mortality among critically ill patients treated in the cardiac intensive care unit. | Pauley E, Lishmanov A, Schumann S, Gala GJ, van Diepen S, Katz JN | American heart journal | 2015 |
APACHE, Acute Kidney Injury, epidemiology, Age Factors, Aged, Cohort Studies, Comorbidity, Critical Illness, Delirium, epidemiology, Female, Heart Arrest, epidemiology, Heart Diseases, epidemiology, Heart Valve Diseases, epidemiology, Humans, Intensive Care Units, Length of Stay, Linear Models, Logistic Models, Male, Middle Aged, Multivariate Analysis, Myocardial Infarction, epidemiology, North Carolina, epidemiology, Prevalence, Prognosis, Respiratory Insufficiency, epidemiology, Sepsis, epidemiology, Severity of Illness Index |
| Return to work six months after burn: A prospective study at the Helsinki Burn Center. | Palmu R, Partonen T, Suominen K, Vuola J, Isometsä E | Burns : journal of the International Society for Burn Injuries | 2015 | |
| Delirium, how does it end? Mortality as an outcome in older medical inpatients. | Muresan ML, Adamis D, Murray O, O'Mahony E, McCarthy G | International journal of geriatric psychiatry | 2015 | |
| Delirium superimposed on dementia: A quantitative and qualitative evaluation of informal caregivers and health care staff experience. | Morandi A, Lucchi E, Turco R, Morghen S, Guerini F, Santi R, Gentile S, Meagher D, Voyer P, Fick DM, Schmitt EM, Inouye SK, Trabucchi M, Bellelli G | Journal of psychosomatic research | 2015 |
Caregivers, psychology, Cohort Studies, Delirium, nursing, Dementia, nursing, Female, Humans, Male, Middle Aged, Patient Care Team, standards, Prospective Studies, Surveys and Questionnaires |
| Delirium superimposed on dementia: A quantitative and qualitative evaluation of patient experience. | Morandi A, Lucchi E, Turco R, Morghen S, Guerini F, Santi R, Gentile S, Meagher D, Voyer P, Fick D, Schmitt EM, Inouye SK, Trabucchi M, Bellelli G | Journal of psychosomatic research | 2015 | |
| Delirium and Circadian Rhythm of Melatonin During Weaning From Mechanical Ventilation: An Ancillary Study of a Weaning Trial. | Mekontso Dessap A, Roche-Campo F, Launay JM, Charles-Nelson A, Katsahian S, Brun-Buisson C, Brochard L | Chest | 2015 |
Aged, Ancillary Services, Hospital, Circadian Rhythm, Delirium, etiology, Female, Follow-Up Studies, Humans, Intensive Care Units, Male, Melatonin, analogs & derivatives, Middle Aged, Respiration, Artificial, Time Factors, Ventilator Weaning, methods |
| Chemotherapeutic drugs that penetrate the blood-brain barrier affect the development of hyperactive delirium in cancer patients. | Matsuoka H, Yoshiuchi K, Koyama A, Otsuka M, Nakagawa K | Palliative & supportive care | 2015 | |
| Patient factors associated with 30-day morbidity, mortality, and length of stay after surgery for subdural hematoma: a study of the American College of Surgeons National Surgical Quality Improvement Program. | Lukasiewicz AM, Grant RA, Basques BA, Webb ML, Samuel AM, Grauer JN | Journal of neurosurgery | 2015 | |
| Preoperative Sleep Disruption and Postoperative Delirium. | Leung JM, Sands LP, Newman S, Meckler G, Xie Y, Gay C, Lee K | Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine | 2015 | |
| Anesthesiologic regimen and intraoperative delirium in deep brain stimulation surgery for Parkinson's disease. | Lange M, Zech N, Seemann M, Janzen A, Halbing D, Zeman F, Doenitz C, Rothenfusser E, Hansen E, Brawanski A, Schlaier J | Journal of the neurological sciences | 2015 | |
| Predicting outcome in older hospital patients with delirium: a systematic literature review. | Jackson TA, Wilson D, Richardson S, Lord JM | International journal of geriatric psychiatry | 2016 | |
| Enhancing Cognitive Aging: Clinical Highlights of a Report From the Institute of Medicine. | Inouye SK | Annals of internal medicine | 2015 | |
| Risk factors associated with postoperative delirium after surgery for oral cancer. | Hasegawa T, Saito I, Takeda D, Iwata E, Yonezawa N, Kakei Y, Sakakibara A, Akashi M, Minamikawa T, Komori T | Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery | 2015 | |
| The Diagnostic Performance of the Richmond Agitation Sedation Scale for Detecting Delirium in Older Emergency Department Patients. | Han JH, Vasilevskis EE, Schnelle JF, Shintani A, Dittus RS, Wilson A, Ely EW | Academic emergency medicine : official journal of the Society for Academic Emergency Medicine | 2015 |
Age Factors, Aged, Aged, 80 and over, Clinical Protocols, Consciousness, Delirium, diagnosis, Emergency Service, Hospital, organization & administration, Female, Humans, Male, Prospective Studies, Reproducibility of Results, Sensitivity and Specificity |
| Risk factors and clinical aspects of delirium in elderly hospitalized patients in Iran. | Foroughan M, Delbari A, Said SE, AkbariKamrani AA, Rashedi V, Zandi T | Aging clinical and experimental research | 2016 | |
| The interface between delirium and dementia in elderly adults. | Fong TG, Davis D, Growdon ME, Albuquerque A, Inouye SK | The Lancet. Neurology | 2015 | |
| Predictors of Long-Term Mortality in Oldest Old Patients (90+) Hospitalized to Medical Wards via the Emergency Department: The SAFES Cohort. | de Boissieu P, Mahmoudi R, Hentzien M, Toquet S, Novella JL, Blanchard F, Jolly D, Dramé M | The journal of nutrition, health & aging | 2015 | |
| Exogenous Melatonin for Delirium Prevention: a Meta-analysis of Randomized Controlled Trials. | Chen S, Shi L, Liang F, Xu L, Desislava D, Wu Q, Zhang J | Molecular neurobiology | 2015 | |
| Efficacy of Non-Pharmacological Interventions to Prevent and Treat Delirium in Older Patients: A Systematic Overview. The SENATOR project ONTOP Series. | Abraha I, Trotta F, Rimland JM, Cruz-Jentoft A, Lozano-Montoya I, Soiza RL, Pierini V, Dessì Fulgheri P, Lattanzio F, O'Mahony D, Cherubini A | PloS one | 2015 | |
| Effect of dexmedetomidine on preventing agitation and delirium after microvascular free flap surgery: a randomized, double-blind, control study. | Yang X, Li Z, Gao C, Liu R | Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons | 2015 | |
| Intraoperative tight glucose control using hyperinsulinemic normoglycemia increases delirium after cardiac surgery. | Saager L, Duncan AE, Yared JP, Hesler BD, You J, Deogaonkar A, Sessler DI, Kurz A | Anesthesiology | 2015 |
Aged, Aged, 80 and over, Blood Glucose, analysis, Cardiac Surgical Procedures, adverse effects, Confusion, psychology, Delirium, chemically induced, Double-Blind Method, Female, Glucose Clamp Technique, Humans, Hyperinsulinism, blood, Intraoperative Care, adverse effects, Male, Middle Aged, Neuropsychological Tests, Postoperative Complications, chemically induced |
| Association between pre-hospital vitamin D status and hospital-acquired new-onset delirium. | Quraishi SA, Litonjua AA, Elias KM, Gibbons FK, Giovannucci E, Camargo CA, Christopher KB | The British journal of nutrition | 2015 | |
| Effect Estimation of an Innovative Nursing Intervention to Improve Delirium among Home-Dwelling Older Adults: A Randomized Controlled Pilot Trial. | Verloo H, Goulet C, Morin D, von Gunten A | Dementia and geriatric cognitive disorders extra | 2015 | |
| Identifying phenomenological differences and recovery of cognitive and non-cognitive symptomatology among delirium superimposed upon dementia patients (DsD) versus those without dementia (DaD) in an acute geriatric care setting. | Chong E, Tay L, Chong MS | International psychogeriatrics / IPA | 2015 | |
| Health economic implications of perioperative delirium in older patients after surgery for a fragility hip fracture. | Zywiel MG, Hurley RT, Perruccio AV, Hancock-Howard RL, Coyte PC, Rampersaud YR | The Journal of bone and joint surgery. American volume | 2015 |
Aged, Aged, 80 and over, Case-Control Studies, Costs and Cost Analysis, Delirium, economics, Female, Fractures, Spontaneous, economics, Hip Fractures, economics, Humans, Length of Stay, economics, Male, Perioperative Care, economics, Postoperative Complications, economics, Propensity Score, Prospective Studies |
| Anticholinergic Medication Use and Transition to Delirium in Critically Ill Patients: A Prospective Cohort Study. | Wolters AE, Zaal IJ, Veldhuijzen DS, Cremer OL, Devlin JW, van Dijk D, Slooter AJ | Critical care medicine | 2015 |
Academic Medical Centers, Age Factors, Aged, Cholinergic Antagonists, adverse effects, Comorbidity, Critical Illness, Delirium, chemically induced, Female, Health Status, Humans, Intensive Care Units, Male, Markov Chains, Middle Aged, Prospective Studies, Risk Factors |
| Preoperative risk factors of postoperative delirium after transurethral prostatectomy for benign prostatic hyperplasia. | Tai S, Xu L, Zhang L, Fan S, Liang C | International journal of clinical and experimental medicine | 2015 | |
| Dexmedetomidine versus Propofol Sedation Reduces Delirium after Cardiac Surgery: A Randomized Controlled Trial. | Djaiani G, Silverton N, Fedorko L, Carroll J, Styra R, Rao V, Katznelson R | Anesthesiology | 2016 | |
| An Innovative Approach to Improving the Accuracy of Delirium Assessments Using the Confusion Assessment Method for the Intensive Care Unit. | DiLibero J, O'Donoghue SC, DeSanto-Madeya S, Felix J, Ninobla A, Woods A | Dimensions of critical care nursing : DCCN | 2016 | |
| Moderate dose melatonin for the abatement and treatment of delirium in elderly general medical inpatients: study protocol of a placebo controlled, randomised, double blind trial. | Clayton-Chubb DI, Lange PW | BMC geriatrics | 2016 | |
| Underdiagnosis of delirium on admission and prediction of patients who will develop delirium during their inpatient stay: a pilot study. | Chin YC, Koh GC, Tay YK, Tan CH, Merchant RA | Singapore medical journal | 2016 | |
| Neural substrates of vulnerability to postsurgical delirium as revealed by presurgical diffusion MRI. | Cavallari M, Dai W, Guttmann CR, Meier DS, Ngo LH, Hshieh TT, Callahan AE, Fong TG, Schmitt E, Dickerson BC, Press DZ, Marcantonio ER, Jones RN, Inouye SK, Alsop DC, | Brain : a journal of neurology | 2016 | |
| Educating Family Caregivers for Older Adults About Delirium: A Systematic Review. | Bull MJ, Boaz L, Jermé M | Worldviews on evidence-based nursing / Sigma Theta Tau International, Honor Society of Nursing | 2016 | |
| Delirium: assessment and treatment of patients with cancer. PART 2. | Brown M, Hardy K | British journal of nursing (Mark Allen Publishing) | 2016 | |
| The Impact of Delirium After Cardiac Surgical Procedures on Postoperative Resource Use. | Brown CH, Laflam A, Max L, Lymar D, Neufeld KJ, Tian J, Shah AS, Whitman GJ, Hogue CW | The Annals of thoracic surgery | 2016 | |
| Sleep and delirium in unsedated patients in the intensive care unit. | Boesen HC, Andersen JH, Bendtsen AO, Jennum PJ | Acta anaesthesiologica Scandinavica | 2016 | |
| Delirium in cardiac ICU patients. | Bamalwa M, Mahmood SN, Praharaj SK | Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists | 2016 | |
| Under Pressure: Reduced Cerebral Perfusion as a Risk Factor for Postoperative Delirium in Lung Transplant Recipients. | Anderson BJ, Diamond JM | Annals of the American Thoracic Society | 2016 | |
| Serum protein S100 as marker of postoperative delirium after off-pump coronary artery bypass surgery: secondary analysis of two prospective randomized controlled trials. | Al Tmimi L, Van de Velde M, Meyns B, Meuris B, Sergeant P, Milisen K, Pottel H, Poesen K, Rex S | Clinical chemistry and laboratory medicine | 2016 | |
| Psychometric evaluation of the DMSS-4 in a cohort of elderly post-operative hip fracture patients with delirium. | Adamis D, Scholtens RM, de Jonghe A, van Munster BC, de Rooij SE, Meagher DJ | International psychogeriatrics / IPA | 2016 | |
| Incidence, Predictive Factors, and Effect of Delirium After Transcatheter Aortic Valve Replacement. | Abawi M, Nijhoff F, Agostoni P, Emmelot-Vonk MH, de Vries R, Doevendans PA, Stella PR | JACC. Cardiovascular interventions | 2016 | |
| Higher serum interieukin-6 is a strong postoperative predictor of delirium after isolated coronary artery bypass graft surgery | Sun, L. Ding, S. Feng, X. Wu, F. Su, P. Shen, Y. Zhao, H. Wu, Y. | Circulation | 2014 |
interleukin 6 |
| Deconstructing dementia and delirium hospital practice: using cultural historical activity theory to inform education approaches. | Teodorczuk A, Mukaetova-Ladinska E, Corbett S, Welfare M | Advances in health sciences education : theory and practice | 2015 |
Delirium, Dementia, England, Female, Focus Groups, Health Personnel, education, Hospitalization, Humans, Interviews as Topic, Male, Quality of Health Care |
| Assessment and Management of Delirium in Older Adults in the Emergency Department: Literature Review to Inform Development of a Novel Clinical Protocol. | Rosen T, Connors S, Clark S, Halpern A, Stern ME, DeWald J, Lachs MS, Flomenbaum N | Advanced emergency nursing journal | 2015 |
Aged, Clinical Protocols, Delirium, diagnosis, Education, Continuing, Emergency Service, Hospital, Humans |
| Gentle persuasive approaches: introducing an educational program on an orthopaedic unit for staff caring for patients with dementia and delirium. | Pizzacalla A, Montemuro M, Coker E, Martin LS, Gillies L, Robinson K, Pepper H, Benner J, Gusciora J | Orthopedic nursing | 2015 |
Critical Care Nursing, education, Curriculum, Delirium, nursing, Dementia, nursing, Humans, Medical Staff, Hospital, education, Nursing Staff, Hospital, education, Orthopedic Nursing, education, Persuasive Communication, Surgery Department, Hospital |
| The 3D-CAM provides a brief, easy to use, sensitive and specific delirium assessment tool for older hospitalised patients, both with and without dementia. | Pisani MA | Evidence-based mental health | 2015 |
Delirium, diagnosis, Female, Humans, Male, Neuropsychological Tests |
| The association of sleep quality, delirium, and sedation status with daily participation in physical therapy in the ICU. | Kamdar BB, Combs MP, Colantuoni E, King LM, Niessen T, Neufeld KJ, Collop NA, Needham DM | Critical care (London, England) | 2015 | |
| Disturbed Serotonergic Neurotransmission and Oxidative Stress in Elderly Patients with Delirium. | Egberts A, Fekkes D, Wijnbeld EH, van der Ploeg MA, van Saase JL, Ziere G, van der Cammen TJ, Mattace-Raso FU | Dementia and geriatric cognitive disorders extra | 2015 | |
| Factors that contribute to underrecognition of delirium by registered nurses in acute care settings: a scoping review of the literature to explain this phenomenon. | El Hussein M, Hirst S, Salyers V | Journal of clinical nursing | 2015 |
Aged, Critical Care Nursing, Delirium, diagnosis, Dementia, complications, Humans |
| Delirium as letting go: An ethnographic analysis of hospice care and family moral experience. | Wright DK, Brajtman S, Cragg B, Macdonald ME | Palliative medicine | 2015 | |
| Non-convulsive status epilepticus: a practical approach to diagnosis in confused older people. | Woodford HJ, George J, Jackson M | Postgraduate medical journal | 2015 | |
| Systemic Corticosteroids and Transition to Delirium in Critically Ill Patients. | Wolters AE, Veldhuijzen DS, Zaal IJ, Peelen LM, van Dijk D, Devlin JW, Slooter AJ | Critical care medicine | 2015 |
Adrenal Cortex Hormones, administration & dosage, Adult, Critical Illness, Delirium, chemically induced, Dose-Response Relationship, Drug, Female, Humans, Intensive Care Units, Logistic Models, Male, Middle Aged, Odds Ratio, Prospective Studies, Psychiatric Status Rating Scales |
| Postoperative delirium assessed by post anesthesia care unit staff utilizing the Nursing Delirium Screening Scale: a prospective observational study of 1000 patients in a single Swiss institution. | Winter A, Steurer MP, Dullenkopf A | BMC anesthesiology | 2015 |
Anesthesia, adverse effects, Anesthesia Recovery Period, Delirium, chemically induced, Feasibility Studies, Female, Humans, Incidence, Male, Middle Aged, Nursing Staff, Hospital, Postoperative Complications, chemically induced, Prospective Studies, Risk Factors, Switzerland |
| Lived experience of the intensive care unit for patients who experienced delirium. | Whitehorne K, Gaudine A, Meadus R, Solberg S | American journal of critical care : an official publication, American Association of Critical-Care Nurses | 2015 | |
| Preoperative protein profiles in cerebrospinal fluid in elderly hip fracture patients at risk for delirium: A proteomics and validation study. | Westhoff D, Witlox J, van Aalst C, Scholtens RM, de Rooij SE, van Munster BC, de Jonghe JF, Houdijk AP, Eikelenboom P, van Westerloo DJ, van de Beek D, van Gool WA, Koenderman L | BBA clinical | 2015 | |
| Variable lung protective mechanical ventilation decreases incidence of postoperative delirium and cognitive dysfunction during open abdominal surgery. | Wang R, Chen J, Wu G | International journal of clinical and experimental medicine | 2015 | |
| Risk factors contributing to postoperative delirium in geriatric patients postorthopedic surgery. | Wang J, Li Z, Yu Y, Li B, Shao G, Wang Q | Asia-Pacific psychiatry : official journal of the Pacific Rim College of Psychiatrists | 2015 | |
| Review of delirium in patients with Parkinson's disease. | Vardy ER, Teodorczuk A, Yarnall AJ | Journal of neurology | 2015 | |
| Delirium detection and improved delirium management in older patients hospitalized for hip fracture. | Todd KS, Barry J, Hoppough S, McConnell E | International journal of orthopaedic and trauma nursing | 2015 | |
| Prospective evaluation of inappropriate unable-to-assess CAM-ICU documentations of critically ill adult patients. | Terry KJ, Anger KE, Szumita PM | Journal of intensive care | 2015 | |
| Delirium in intensive care unit patients under noninvasive ventilation: a multinational survey. | Tanaka LM, Salluh JI, Dal-Pizzol F, Barreto BB, Zantieff R, Tobar E, Esquinas A, Quarantini Lde C, Gusmao-Flores D | Revista Brasileira de terapia intensiva | 2015 |
Attitude of Health Personnel, Critical Care, Delirium, diagnosis, Health Care Surveys, Humans, Intensive Care Units, Noninvasive Ventilation |
| Acetylcholinesterase Inhibitors for Delirium in Older Adults. | Tampi RR, Tampi DJ, Ghori AK | American journal of Alzheimer's disease and other dementias | 2016 | |
| Influence of Granulocyte-Macrophage Colony-Stimulating Factor or Influenza Vaccination on HLA-DR, Infection and Delirium Days in Immunosuppressed Surgical Patients: Double Blind, Randomised Controlled Trial. | Spies C, Luetz A, Lachmann G, Renius M, von Haefen C, Wernecke KD, Bahra M, Schiemann A, Paupers M, Meisel C | PloS one | 2015 | |
| Validation of the confusion assessment method in detecting postoperative delirium in cardiac surgery patients. | Smulter N, Lingehall HC, Gustafson Y, Olofsson B, Engström KG | American journal of critical care : an official publication, American Association of Critical-Care Nurses | 2015 | |
| Risk Factors for Delirium After Spinal Surgery: A Meta-Analysis. | Shi C, Yang C, Gao R, Yuan W | World neurosurgery | 2015 |
Aged, Aged, 80 and over, Delirium, epidemiology, Humans, Neurosurgical Procedures, adverse effects, Postoperative Complications, epidemiology, Risk Factors, Spine, surgery |
| Valproic Acid for Treatment of Hyperactive or Mixed Delirium: Rationale and Literature Review. | Sher Y, Miller Cramer AC, Ament A, Lolak S, Maldonado JR | Psychosomatics | 2015 | |
| The Successful Aging After Elective Surgery Study: Cohort Description and Data Quality Procedures. | Schmitt EM, Saczynski JS, Kosar CM, Jones RN, Alsop DC, Fong TG, Metzger E, Cooper Z, Marcantonio ER, Travison T, Inouye SK, | Journal of the American Geriatrics Society | 2015 | |
| The Montreal Cognitive Assessment: Creating a Crosswalk with the Mini-Mental State Examination. | Saczynski JS, Inouye SK, Guess J, Jones RN, Fong TG, Nemeth E, Hodara A, Ngo L, Marcantonio ER | Journal of the American Geriatrics Society | 2015 |
Aged, Aged, 80 and over, Cognition Disorders, diagnosis, Cross-Sectional Studies, Delirium, diagnosis, Dementia, diagnosis, Female, Humans, Male, Mild Cognitive Impairment, diagnosis, Neuropsychological Tests |
| Delirium After Hip Fracture: Still a Problem. | Rudolph JL | Anesthesia and analgesia | 2015 |
Delirium, mortality, Female, Hip Fractures, mortality, Humans, Male, Postoperative Complications, mortality |
| The Bromhead Care Home Service: the impact of a service for care home residents with dementia on hospital admission and dying in preferred place of care. | Garden G, Green S, Pieniak S, Gladman J | Clinical medicine (London, England) | 2016 |