What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- The association between the inflammatory response following surgery and post-operative delirium in older oncological patients: a prospective cohort study
- Authors
- Brattinga, B. Plas, M. Spikman, J. M. Rutgers, A. de Haan, J. J. Absalom, A. R. van der Wal-Huisman, H. de Bock, G. H. van Leeuwen, B. L.
- Year
- 2022
- Journal
- Age Ageing
- Abstract
INTRODUCTION: Post-operative delirium (POD) is associated with increased morbidity and mortality rates in older patients. Neuroinflammation, the activation of the intrinsic immune system of the brain, seems to be one of the mechanisms behind the development of POD. The aim of this study was to explore the association between the perioperative inflammatory response and the development of POD in a cohort of older oncological patients in need for surgery. METHODS: In this prospective cohort study, patients 65 years and older in need for oncologic surgery were included. Inflammatory markers C-reactive protein (CRP), interleukin-1 beta (IL-1β), IL-6, IL10 and Neutrophil gelatinase-associated lipocalin (NGAL) were measured in plasma samples pre- and post-operatively. Delirium Observation Screening Scale (DOS) was used as screening instrument for POD in the first week after surgery. In case of positive screening, diagnosis of POD was assessed by a clinician. RESULTS: Between 2010 and 2016, plasma samples of 311 patients with median age of 72 years (range 65-89) were collected. A total of 38 (12%) patients developed POD in the first week after surgery. The perioperative increase in plasma levels of IL-10 and NGAL were associated with POD in multivariate logistic regression analysis (OR 1.33 [1.09-1.63] P = 0.005 and OR 1.30 [1.03-1.64], P = 0.026, respectively). The biomarkers CRP, IL-1β and IL-6 were not significantly associated with POD. CONCLUSIONS: Increased surgery-evoked inflammatory responses of IL-10 and NGAL are associated with the development of POD in older oncological patients. The outcomes of this study contribute to understanding the aetiology of neuroinflammation and the development of POD.
- PMID
- Keywords
Aged
Aged, 80 and over
C-Reactive Protein/analysis
Cohort Studies
*Delirium/diagnosis/etiology
Humans
*Postoperative Complications/diagnosis/etiology
Prospective Studies
*Post-operative delirium
*cancer
*inflammatory response
*neuroinflammation
*older patients
*older people
- Page(s)
- Volume
- 51
- Issue
- 2
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| Effect of intensive care unit environment on in-hospital delirium after cardiac surgery. | Arenson BG, MacDonald LA, Grocott HP, Hiebert BM, Arora RC | The Journal of thoracic and cardiovascular surgery | 2013 |
Aged, Cardiac Surgical Procedures, Delirium, epidemiology, Female, Hospitals, Humans, Intensive Care Units, Male, Middle Aged, Postoperative Complications, epidemiology, Retrospective Studies |
| Parenteral hydration in patients with advanced cancer: a multicenter, double-blind, placebo-controlled randomized trial. | Bruera E, Hui D, Dalal S, Torres-Vigil I, Trumble J, Roosth J, Krauter S, Strickland C, Unger K, Palmer JL, Allo J, Frisbee-Hume S, Tarleton K | Journal of clinical oncology : official journal of the American Society of Clinical Oncology | 2013 |
Adult, Aged, Aged, 80 and over, Dehydration, therapy, Double-Blind Method, Fatigue, prevention & control, Female, Fluid Therapy, Follow-Up Studies, Hospice Care, Humans, Male, Middle Aged, Neoplasm Recurrence, Local, complications, Neoplasms, complications, Parenteral Nutrition, Prognosis, Quality of Life, Survival Rate, Symptom Assessment |
| Delirium assessment using Confusion Assessment Method for the Intensive Care Unit in Chinese critically ill patients. | Wang C, Wu Y, Yue P, Ely EW, Huang J, Yang X, Liu Y | Journal of critical care | 2013 |
APACHE, Activities of Daily Living, Aged, Chi-Square Distribution, China, Confusion, diagnosis, Critical Illness, Delirium, diagnosis, Diagnostic and Statistical Manual of Mental Disorders, Female, Humans, Intensive Care Units, Male, Middle Aged, Predictive Value of Tests, Reproducibility of Results, Sensitivity and Specificity, Translations |
| Incidence, risk factors, and complications of postoperative delirium in elderly patients undergoing radical cystectomy. | Large MC, Reichard C, Williams JT, Chang C, Prasad S, Leung Y, DuBeau C, Bales GT, Steinberg GD | Urology | 2013 |
Age Factors, Aged, Aged, 80 and over, Case-Control Studies, Confidence Intervals, Cystectomy, adverse effects, Delirium, etiology, Female, Humans, Kaplan-Meier Estimate, Male, Mental Status Schedule, Multivariate Analysis, Odds Ratio, Patient Readmission, Pilot Projects, Prospective Studies, Reoperation, Risk Factors, Urinary Bladder Neoplasms, surgery |
| Delirium in older patients: a diagnostic study of NEECHAM Confusion Scale in surgical intensive care unit. | Matarese M, Generoso S, Ivziku D, Pedone C, De Marinis MG | Journal of clinical nursing | 2013 |
Aged, Confusion, diagnosis, Humans, Intensive Care Units, Prospective Studies, Surgery Department, Hospital |
| Subsyndromal delirium in older people: a systematic review of frequency, risk factors, course and outcomes. | Cole MG, Ciampi A, Belzile E, Dubuc-Sarrasin M | International journal of geriatric psychiatry | 2013 |
Canada, epidemiology, Delirium, epidemiology, Europe, epidemiology, Humans, Incidence, Institutionalization, statistics & numerical data, Outcome Assessment (Health Care), Prevalence, Risk Factors, United States, epidemiology |
| Intensive care unit environment may affect the course of delirium. | Zaal IJ, Spruyt CF, Peelen LM, van Eijk MM, Wientjes R, Schneider MM, Kesecioglu J, Slooter AJ | Intensive care medicine | 2013 |
Delirium, epidemiology, Female, Health Facility Environment, Humans, Intensive Care Units, Male, Middle Aged, Prospective Studies |
| The incidence of delirium in Norwegian intensive care units; deep sedation makes assessment difficult. | Wøien H, Balsliemke S, Stubhaug A | Acta anaesthesiologica Scandinavica | 2013 |
Adolescent, Adult, Aged, Aged, 80 and over, Analgesics, therapeutic use, Coma, therapy, Critical Illness, Data Collection, Data Interpretation, Statistical, Deep Sedation, Delirium, diagnosis, Female, Humans, Intensive Care Units, statistics & numerical data, Logistic Models, Male, Middle Aged, Norway, epidemiology, Pain Measurement, Psychomotor Agitation, Young Adult |
| Replication analysis for composition of the Delirium Motor Subtype Scale (DMSS) in a referral cohort from Northern India. | Grover S, Mattoo SK, Aarya KR, Pratim Das P, Chakrabarty K, Trzepacz P, Gupta N, Meagher D | Psychiatry research | 2013 |
Adolescent, Adult, Aged, Aged, 80 and over, Cohort Studies, Delirium, classification, Female, Humans, India, Male, Middle Aged, Movement Disorders, classification, Principal Component Analysis, Psychiatric Status Rating Scales, Referral and Consultation, Severity of Illness Index, Young Adult |
| Prospective observational study of dementia and delirium in the acute hospital setting. | Travers C, Byrne G, Pachana N, Klein K, Gray L | Internal medicine journal | 2013 |
Aged, Aged, 80 and over, Cohort Studies, Delirium, diagnosis, Dementia, diagnosis, Female, Hospitalization, trends, Humans, Male, Observational Study as Topic, methods, Patient Admission, trends, Prospective Studies, Queensland, epidemiology |
| Melatonin receptor agonists for treating delirium in elderly patients with acute stroke. | Ohta T, Murao K, Miyake K, Takemoto K | Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association | 2013 |
Aged, Aged, 80 and over, Delirium, complications, Female, Humans, Indenes, therapeutic use, Male, Middle Aged, Prognosis, Receptors, Melatonin, agonists, Stroke, complications, Treatment Outcome |
| Selecting optimal screening items for delirium: an application of item response theory. | Yang FM, Jones RN, Inouye SK, Tommet D, Crane PK, Rudolph JL, Ngo LH, Marcantonio ER | BMC medical research methodology | 2013 |
Aged, 80 and over, Algorithms, Delirium, diagnosis, Factor Analysis, Statistical, Female, Humans, Male, Psychometrics, Questionnaires |
| Relation of serum cortisol to delirium occurring after acute coronary syndromes. | Colkesen Y, Giray S, Ozenli Y, Sezgin N, Coskun I | The American journal of emergency medicine | 2013 |
Acute Coronary Syndrome, complications, Aged, Delirium, blood, Female, Humans, Hydrocortisone, blood, Logistic Models, Male, Middle Aged, Psychiatric Status Rating Scales, ROC Curve, Risk Assessment, Sensitivity and Specificity, Severity of Illness Index |
| Vitamin D and delirium in critically ill patients: a preliminary investigation. | Morandi A, Barnett N, Miller RR, Girard TD, Pandharipande PP, Ely EW, Ware LB | Journal of critical care | 2013 |
Acute Lung Injury, diagnosis, Adult, Age Factors, Critical Illness, Delirium, blood, Female, Humans, Intensive Care Units, Logistic Models, Male, Middle Aged, Pilot Projects, Prospective Studies, Risk Factors, Severity of Illness Index, Vitamin D Deficiency, blood |
| Delirium within the emergency care setting, occurrence and detection: a systematic review. | Barron EA, Holmes J | Emergency medicine journal : EMJ | 2013 |
Cohort Studies, Cross-Sectional Studies, Delirium, epidemiology, Emergency Service, Hospital, statistics & numerical data, Great Britain, epidemiology, Humans, Incidence, Prevalence |
| Delirium and transition to a nursing home of hospitalized older adults: a controlled trial of assessing the interdisciplinary team-based "geriatric" care and care coordination by non-geriatrics specialist physicians. | Yoo JW, Nakagawa S, Kim S | Geriatrics & gerontology international | 2013 |
Activities of Daily Living, Aged, Aged, 80 and over, Case Management, Case-Control Studies, Checklist, Cognition, physiology, Delirium, prevention & control, Diagnosis, Female, Follow-Up Studies, Geriatric Assessment, Geriatrics, education, Hospitalization, Humans, Intervention Studies, Male, Medication Reconciliation, Medicine, Mental Status Schedule, Nursing Homes, Outcome Assessment (Health Care), Patient Care Team, Patient Transfer, Residence Characteristics, Severity of Illness Index, Sleep, physiology |
| Impact of pneumonia on hyperactive delirium in end-stage lung cancer patients. | Suzuki H, Hirashima T, Kobayashi M, Okamoto N, Matsuura Y, Tamiya M, Morishita N, Okafuji K, Shiroyama T, Morimura O, Morita S, Kawase I | Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer | 2013 |
Adult, Aged, Aged, 80 and over, Case-Control Studies, Delirium, epidemiology, Female, Humans, Incidence, Japan, epidemiology, Logistic Models, Lung Neoplasms, epidemiology, Male, Middle Aged, Multivariate Analysis, Palliative Care, Pneumonia, epidemiology, Psychomotor Agitation, epidemiology, Retrospective Studies, Risk Factors |
| Improving quality of delirium care in a general medical service with established interdisciplinary care: a controlled trial. | Mudge AM, Maussen C, Duncan J, Denaro CP | Internal medicine journal | 2013 |
Aged, Aged, 80 and over, Delirium, diagnosis, Female, General Practice, standards, Hospital Departments, standards, Humans, Male, Patient Care Team, standards, Patient Discharge, standards, Quality Improvement, standards |
| Incidence of post-stroke delirium and 1-year outcome. | Miu DK, Yeung JC | Geriatrics & gerontology international | 2013 |
Aged, Aged, 80 and over, Biological Markers, analysis, Comorbidity, Delirium, epidemiology, Demography, Female, Hong Kong, epidemiology, Humans, Incidence, Length of Stay, statistics & numerical data, Logistic Models, Male, Middle Aged, Risk Factors, Stroke, complications, Survival Rate |
| Prevalence, presentation and prognosis of delirium in older people in the population, at home and in long term care: a review. | de Lange E, Verhaak PF, van der Meer K | International journal of geriatric psychiatry | 2013 |
Delirium, epidemiology, Home Care Services, statistics & numerical data, Humans, Long-Term Care, statistics & numerical data, Prevalence, Prognosis, Risk Factors |
| Postoperative course after emergency colorectal surgery for secondary peritonitis in the elderly is often complicated by delirium. | Engelberger S, Zürcher M, Schuld J, Viehl CT, Kettelhack C | International surgery | 2012 |
APACHE, Age Factors, Aged, Aged, 80 and over, Colon, surgery, Decision Support Techniques, Delirium, diagnosis, Emergencies, Female, Humans, Male, Peritonitis, etiology, Postoperative Complications, epidemiology, Rectum, surgery, Retrospective Studies, Risk Factors, Severity of Illness Index, Treatment Outcome |
| Cortical signatures of cognition and their relationship to Alzheimer's disease. | Gross AL, Manly JJ, Pa J, Johnson JK, Park LQ, Mitchell MB, Melrose RJ, Inouye SK, McLaren DG, | Brain imaging and behavior | 2012 |
Aged, Aged, 80 and over, Alzheimer Disease, complications, Brain, pathology, Diagnosis, Computer-Assisted, methods, Female, Humans, Magnetic Resonance Imaging, methods, Male, Middle Aged, Mild Cognitive Impairment, complications, Neuropsychological Tests, Psychometrics, methods, Reproducibility of Results, Sensitivity and Specificity, Severity of Illness Index |
| Parallel but not equivalent: challenges and solutions for repeated assessment of cognition over time. | Gross AL, Inouye SK, Rebok GW, Brandt J, Crane PK, Parisi JM, Tommet D, Bandeen-Roche K, Carlson MC, Jones RN | Journal of clinical and experimental neuropsychology | 2012 |
Aged, Aged, 80 and over, Cognition, Cognition Disorders, diagnosis, Female, Humans, Individuality, Longitudinal Studies, Male, Neuropsychological Tests, Verbal Learning |
| Novel risk markers and long-term outcomes of delirium: the successful aging after elective surgery (SAGES) study design and methods. | Schmitt EM, Marcantonio ER, Alsop DC, Jones RN, Rogers SO, Fong TG, Metzger E, Inouye SK, | Journal of the American Medical Directors Association | 2012 |
Academic Medical Centers, Aged, Aging, Biological Markers, blood, Boston, Databases, Factual, Delirium, etiology, Female, Humans, Postoperative Complications, Prospective Studies, Qualitative Research, Research Design, Risk Assessment, methods, Surgical Procedures, Elective |
| Serial administration of a modified Richmond Agitation and Sedation Scale for delirium screening. | Chester JG, Beth Harrington M, Rudolph JL, | Journal of hospital medicine : an official publication of the Society of Hospital Medicine | 2012 |
Aged, Aged, 80 and over, Cohort Studies, Delirium, diagnosis, Female, Humans, Male, Prospective Studies, Psychiatric Status Rating Scales, standards, Psychomotor Agitation, diagnosis |
| Intracranial cause of delirium: computed tomography yield and predictive factors. | Lai MM, Wong Tin Niam DM | Internal medicine journal | 2012 |
Aged, Aged, 80 and over, Australia, Brain, pathology, Brain Diseases, complications, Case-Control Studies, Delirium, etiology, Female, Humans, Male, Middle Aged, Predictive Value of Tests, Risk Factors, Sensitivity and Specificity, Tomography, X-Ray Computed |
| Role of microglia and toll-like receptor 4 in the pathophysiology of delirium. | Jalleh R, Koh K, Choi B, Liu E, Maddison J, Hutchinson MR | Medical hypotheses | 2012 |
Aged, Delirium, physiopathology, Humans, Microglia, pathology, Middle Aged, Models, Theoretical, Toll-Like Receptor 4, physiology |
| Non-steroidal anti-inflammatory drugs and cognitive function: are prostaglandins at the heart of cognitive impairment in dementia and delirium? | Cunningham C, Skelly DT | Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology | 2012 |
Animals, Anti-Inflammatory Agents, Non-Steroidal, pharmacology, Cognition, drug effects, Cognition Disorders, immunology, Delirium, immunology, Dementia, immunology, Humans, Prostaglandins, immunology |
| Postoperative delirium in intensive care patients: risk factors and outcome. | Veiga D, Luis C, Parente D, Fernandes V, Botelho M, Santos P, Abelha F | Revista brasileira de anestesiologia | 2012 |
Anesthesia Recovery Period Delirium Postoperative Complications Risk Factors |
| Pain and cognitive dysfunction are the risk factors of delirium in elderly hip fracture Chinese patients. | Nie H, Zhao B, Zhang YQ, Jiang YH, Yang YX | Archives of gerontology and geriatrics | 2012 |
Aged, China, epidemiology, Cognition Disorders, complications, Delirium, epidemiology, Female, Hip Fractures, complications, Humans, Incidence, Male, Neuropsychological Tests, Pain, complications, Pain Measurement, Postoperative Complications, etiology, Prospective Studies, Risk Factors |
| Pain reporting, opiate dosing, and the adverse effects of opiates after hip or knee replacement in patients 60 years old or older. | Petre BM, Roxbury CR, McCallum JR, Defontes KW, Belkoff SM, Mears SC | Geriatric orthopaedic surgery & rehabilitation | 2012 |
Elderly Hip Replacement Knee Replacement Opiates Pain |
| Bright light therapy as an adjunctive treatment with risperidone in patients with delirium: a randomized, open, parallel group study. | Yang J, Choi W, Ko YH, Joe SH, Han C, Kim YK | General hospital psychiatry | 2012 |
Adjunctive treatment Delirium Light Therapy Sleep Efficiency Total Sleep Time |
| Pharmacological risk factors for delirium after cardiac surgery: a review. | Tse L, Schwarz SK, Bowering JB, Moore RL, Burns KD, Richford CM, Osborn JA, Barr AM | Current neuropharmacology | 2012 |
Cardiac surgery, Delirium, Drugs, Medications, Prevent, Risk Factors |
| One-year mortality of elderly inpatients with delirium, dementia, or depression seen by a consultation-liaison service. | Tsai MC, Weng HH, Chou SY, Tsai CS, Hung TH, Su JA | Psychosomatics | 2012 |
Age Factors, Aged, Aged, 80 and over, Delirium, mortality, Dementia, mortality, Depressive Disorder, mortality, Female, Humans, Length of Stay, statistics & numerical data, Logistic Models, Male, Referral and Consultation, Risk Factors, Sex Factors |
| Risk factors for delirium in patients undergoing hematopoietic stem cell transplantation. | Weckmann MT, Gingrich R, Mills JA, Hook L, Beglinger LJ | Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists | 2012 |
Adult, Aged, Anemia, complications, Anoxia, complications, Blood Urea Nitrogen, Creatinine, blood, Dehydration, complications, Delirium, epidemiology, Erythrocyte Indices, Female, Hematopoietic Stem Cell Transplantation, adverse effects, Hemoglobins, analysis, Humans, Male, Middle Aged, Neoplasms, therapy, Prospective Studies, Risk Factors, Serum Albumin, analysis |
| What are the opportunities for EEG-based monitoring of delirium in the ICU? | van der Kooi AW, Leijten FS, van der Wekken RJ, Slooter AJ | The Journal of neuropsychiatry and clinical neurosciences | 2012 |
Cerebral Cortex, physiopathology, Delirium, diagnosis, Electroencephalography, Humans, Intensive Care, Intensive Care Units |
| Diurnal sedative changes during intensive care: impact on liberation from mechanical ventilation and delirium. | Seymour CW, Pandharipande PP, Koestner T, Hudson LD, Thompson JL, Shintani AK, Ely EW, Girard TD | Critical care medicine | 2012 |
Aged, Benzodiazepines, administration & dosage, Circadian Rhythm, Clinical Protocols, Coma, chemically induced, Delirium, chemically induced, Dose-Response Relationship, Drug, Drug Therapy, Combination, Female, Humans, Hypnotics and Sedatives, administration & dosage, Intensive Care, statistics & numerical data, Male, Middle Aged, Propofol, administration & dosage, Prospective Studies, Respiration, Artificial, methods, Ventilator Weaning, statistics & numerical data |
| Delirium in postoperative nonventilated intensive care patients: risk factors and outcomes. | Serafim RB, Dutra MF, Saddy F, Tura B, de Castro JE, Villarinho LC, da Gloria Santos M, Bozza FA, Rocco JR | Annals of intensive care | 2012 |
Delirium Postoperative Surgery Confusion assessment method |
| Overview of significant changes in the Minimum Data Set for nursing homes version 3.0. | Saliba D, Jones M, Streim J, Ouslander J, Berlowitz D, Buchanan J | Journal of the American Medical Directors Association | 2012 |
Aged, Data Collection, methods, Geriatric Assessment, methods, Humans, Medicare, Nursing Homes, Patient Admission, standards, United States, United States Department of Veterans Affairs, standards |
| Effectiveness of acute geriatric unit care using acute care for elders components: a systematic review and meta-analysis. | Fox MT, Persaud M, Maimets I, O'Brien K, Brooks D, Tregunno D, Schraa E | Journal of the American Geriatrics Society | 2012 |
Accidental Falls, statistics & numerical data, Activities of Daily Living, Aged, Aged, 80 and over, Female, Geriatrics, Hospital Mortality, Hospital Units, economics, Humans, Length of Stay, Male, Patient Discharge, Patient Readmission, statistics & numerical data, Patient-Centered Care, statistics & numerical data, Pressure Ulcer, epidemiology, Quality of Health Care |
| An evaluation of a proactive geriatric trauma consultation service. | Lenartowicz M, Parkovnick M, McFarlan A, Haas B, Straus SE, Nathens AB, Wong CL | Annals of surgery | 2012 |
Aged, Female, Health Services for the Aged, Humans, Male, Models, Theoretical, Retrospective Studies, Trauma Centers, Wounds and Injuries, therapy |
| Obstructive sleep apnea and delirium: exploring possible mechanisms. | Mirrakhimov AE, Brewbaker CL, Krystal AD, Kwatra MM | Sleep & breathing = Schlaf & Atmung | 2014 | |
| Effects of hospitalist-directed interdisciplinary medicine floor service on hospital outcomes for seniors with acute medical illness. | Yoo JW, Seol H, Kim SJ, Yang JM, Ryu WS, Min TD, Choi JB, Kwon M, Kim S | Geriatrics & gerontology international | 2014 | |
| Oropharyngeal dysphagia in an elderly post-operative hip fracture population: a prospective cohort study. | Love AL, Cornwell PL, Whitehouse SL | Age and ageing | 2013 |
Age Factors, Aged, Aged, 80 and over, Comorbidity, Deglutition, Deglutition Disorders, diagnosis, Delirium, epidemiology, Fracture Fixation, adverse effects, Hip Fractures, epidemiology, Homes for the Aged, Humans, Incidence, Length of Stay, Logistic Models, Multivariate Analysis, Prospective Studies, Queensland, epidemiology, Risk Factors, Time Factors, Treatment Outcome |
| Melatonin deficiency hypothesis in delirium: a synthesis of current evidence. | de Rooij SE, van Munster BC | Rejuvenation research | 2013 |
Animals, Circadian Rhythm, Delirium, metabolism, Humans, Melatonin, deficiency, Models, Biological, Risk Factors |
| Pathophysiology of encephalopathy and delirium. | Williams ST | Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society | 2013 |
Brain Diseases, physiopathology, Delirium, physiopathology, Humans |
| Bedside coaching to improve nurses' recognition of delirium. | Gordon SJ, Melillo KD, Nannini A, Lakatos BE | The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses | 2013 |
Adult, Delirium, diagnosis, Education, Nursing, Continuing, methods, Evidence-Based Nursing, methods, Health Knowledge, Attitudes, Practice, Humans, Male, Middle Aged, Nursing Assessment, methods, Nursing Staff, Hospital, education, Questionnaires, Retrospective Studies, Risk Factors, Staff Development, methods, Young Adult |
| Delirium: past, present, and future. | Field RR, Wall MH | Seminars in cardiothoracic and vascular anesthesia | 2013 |
Delirium, diagnosis, Humans, Postoperative Complications, etiology, Respiration, Artificial |
| Incidence and risk factors for postoperative delirium after lumbar spine surgery. | Fineberg SJ, Nandyala SV, Marquez-Lara A, Oglesby M, Patel AA, Singh K | Spine | 2013 |
Adolescent, Adult, Age Factors, Aged, Comorbidity, Decompression, Surgical, adverse effects, Delirium, epidemiology, Female, Hospital Costs, Humans, Incidence, Inpatients, statistics & numerical data, Logistic Models, Lumbar Vertebrae, surgery, Male, Middle Aged, Nervous System Diseases, epidemiology, Postoperative Complications, epidemiology, Retrospective Studies, Risk Factors, Spinal Fusion, adverse effects, Substance-Related Disorders, epidemiology, Survival Rate, United States, epidemiology, Young Adult |
| The triple challenge of recruiting older adults with dementia and high medical acuity in skilled nursing facilities. | Kolanowski A, Mulhall P, Yevchak A, Hill N, Fick D | Journal of nursing scholarship : an official publication of Sigma Theta Tau International Honor Society of Nursing / Sigma Theta Tau | 2013 |
Aged, Aged, 80 and over, Delirium, complications, Dementia, complications, Female, Humans, Male, Nursing Research, organization & administration, Patient Selection, Skilled Nursing Facilities |
| Medications, delirium, and older adults. | Bell L | American journal of critical care : an official publication, American Association of Critical-Care Nurses | 2013 |
Aged, Aged, 80 and over, Delirium, diagnosis, Humans, Practice Guidelines as Topic, Risk Factors |
| Surgery in elderly people: preoperative, operative and postoperative care to assist healing. | Hughes S, Leary A, Zweizig S, Cain J | Best practice & research. Clinical obstetrics & gynaecology | 2013 |
Aged, Aging, Delirium, prevention & control, Female, Humans, Pain Management, methods, Pain, Postoperative, therapy, Patient Discharge, Patient Positioning, Postoperative Care, methods, Preoperative Care, methods, Recovery of Function, physiology, Risk Factors, Surgical Procedures, Operative, rehabilitation, Venous Thromboembolism, prevention & control, Wound Healing |
| Delirium in older people after proximal femoral fracture repair: role of a preoperative screening cognitive test. | Mézière A, Paillaud E, Belmin J, Pariel S, Herbaud S, Canouï-Poitrine F, Le Thuaut A, Marty J, Plaud B | Annales françaises d'anesthèsie et de rèanimation | 2013 |
Aged, Aged, 80 and over, Cohort Studies, Comorbidity, Delirium, epidemiology, Depression, complications, Educational Status, Female, Femoral Fractures, surgery, Humans, Male, Mental Recall, physiology, Neuropsychological Tests, Orthopedic Procedures, Postoperative Complications, epidemiology, Preoperative Period, Prospective Studies, Risk Factors |
| Management of acute confusion in patients with CNS infections. | Matata C, Defres S, Jones C, Gummery A, Solomon T | Nursing standard (Royal College of Nursing (Great Britain) : 1987) | 2013 |
Acute Disease, nursing, Adult, Aggression, Central Nervous System Infections, complications, Confusion, etiology, Curriculum, Delirium, etiology, Female, Great Britain, Humans, Male, Middle Aged, Nursing Staff, Hospital, education, Practice Guidelines as Topic, Risk Factors |
| Identification and rates of delirium in elderly medical inpatients from diverse language groups. | Wand AP, Thoo W, Ting V, Baker J, Sciuriaga H, Hunt GE | Geriatric nursing (New York, N.Y.) | 2013 |
Aged, Aged, 80 and over, Delirium, epidemiology, Female, Humans, Inpatients, Language, Male |
| The aging brain and anesthesia. | Brown EN, Purdon PL | Current opinion in anaesthesiology | 2013 |
Aged, Aging, pathology, Anesthesia, methods, Animals, Brain, pathology, Electroencephalography, Humans, Mild Cognitive Impairment, physiopathology, Oxidative Stress |
| Apolipoprotein E ε4 is superior to apolipoprotein E ε2 in predicting cognitive scores over 30 months. | Regal P, Nair B, Hetherington E | Clinical interventions in aging | 2013 |
Aged, Aged, 80 and over, Apolipoprotein E2, genetics, Apolipoprotein E4, genetics, Cognition Disorders, diagnosis, Cohort Studies, Female, Genetic Markers, Humans, Male, Neuropsychological Tests, New South Wales, Predictive Value of Tests, Prospective Studies, Sex Distribution |
| Army anesthesia providers' perceptions of emergence delirium after general anesthesia in service members. | Wilson JT | AANA journal | 2013 |
Anesthesia Recovery Period, Anesthesia, General, adverse effects, Anesthesiology, Delirium, epidemiology, Female, Health Care Surveys, Humans, Male, Military Nursing, Military Personnel, statistics & numerical data, Nurse Anesthetists, Perception, Questionnaires |
| Incidence of cholinesterase inhibitor therapy initiation among hospitalized patients. | Swan JT, Wagle KC, Thompson-Moore N, Taffet GE | Journal of hospital medicine : an official publication of the Society of Hospital Medicine | 2013 |
Aged, Aged, 80 and over, Cholinesterase Inhibitors, adverse effects, Cross-Sectional Studies, Delirium, drug therapy, Female, Hospital Mortality, trends, Hospitalization, trends, Humans, Incidence, Male, Retrospective Studies |
| Assessment of people with cognitive impairment and hip fracture: a systematic review and meta-analysis. | Smith T, Hameed Y, Cross J, Sahota O, Fox C | Archives of gerontology and geriatrics | 2013 |
Aged, Aged, 80 and over, Cognition Disorders, complications, Delirium, complications, Female, Geriatric Assessment, methods, Hip Fractures, complications, Humans, Male, Neuropsychological Tests, Pain Measurement |
| Atypical antipsychotics in the treatment of delirium. | Wang HR, Woo YS, Bahk WM | Psychiatry and clinical neurosciences | 2013 |
Antipsychotic Agents, adverse effects, Benzodiazepines, therapeutic use, Delirium, drug therapy, Dibenzothiazepines, therapeutic use, Humans, Piperazines, therapeutic use, Randomized Controlled Trials as Topic, Risperidone, therapeutic use, Sulpiride, analogs & derivatives, Thiazoles, therapeutic use |
| The delirium experience: what is the effect on patients, relatives and staff and what can be done to modify this? | Partridge JS, Martin FC, Harari D, Dhesi JK | International journal of geriatric psychiatry | 2013 |
Anxiety, etiology, Delirium, psychology, Depression, etiology, Family, psychology, Health Personnel, psychology, Humans, Mental Recall, Qualitative Research, Stress Disorders, Post-Traumatic, etiology, Stress, Psychological, etiology |
| Development of an amygdalocentric neurocircuitry-reactive aggression theoretical model of emergence delirium in posttraumatic stress disorder: an integrative literature review. | McLott J, Jurecic J, Hemphill L, Dunn KS | AANA journal | 2013 |
Amygdala, physiopathology, Anesthesia, General, adverse effects, Combat Disorders, complications, Delirium, chemically induced, Humans, Nurse Anesthetists, Postoperative Complications, chemically induced, Stress Disorders, Post-Traumatic, complications |
| Quetiapine for the treatment of delirium. | Hawkins SB, Bucklin M, Muzyk AJ | Journal of hospital medicine : an official publication of the Society of Hospital Medicine | 2013 |
Antipsychotic Agents, therapeutic use, Delirium, drug therapy, Dibenzothiazepines, therapeutic use, Humans, Randomized Controlled Trials as Topic, methods, Retrospective Studies, Treatment Outcome |
| Delirium after cardiac surgery: have we overlooked obstructive sleep apnea? | Mirrakhimov AE, Yen T, Kwatra MM | Medical hypotheses | 2013 |
Delirium, etiology, Humans, Models, Theoretical, Risk Factors, Sleep Apnea, Obstructive, complications, Thoracic Surgical Procedures, adverse effects |
| Melatonin: delirium (postsurgical). | Generali JA, Cada DJ | Hospital pharmacy | 2013 | |
| Delirium: ramelton. | Generali JA, Cada DJ | Hospital pharmacy | 2013 | |
| Prophylactic antipsychotic use for postoperative delirium: a systematic review and meta-analysis. | Hirota T, Kishi T | The Journal of clinical psychiatry | 2013 |
Antipsychotic Agents, classification, Chemoprevention, Comparative Effectiveness Research, Delirium, diagnosis, Humans, Patient Selection, Postoperative Complications, diagnosis, Psychiatric Status Rating Scales, Randomized Controlled Trials as Topic, Risk Assessment, Therapeutic Equivalency |
| Slower walking speed forecasts increased postoperative morbidity and 1-year mortality across surgical specialties. | Robinson TN, Wu DS, Sauaia A, Dunn CL, Stevens-Lapsley JE, Moss M, Stiegmann GV, Gajdos C, Cleveland JC, Inouye SK | Annals of surgery | 2013 |
Aged, Aged, 80 and over, Cardiac Surgical Procedures, mortality, Decision Support Techniques, Digestive System Surgical Procedures, mortality, Female, Follow-Up Studies, Humans, Kaplan-Meier Estimate, Male, Postoperative Complications, diagnosis, Preoperative Care, Prognosis, Prospective Studies, ROC Curve, Risk Assessment, Risk Factors, Surgical Procedures, Elective, mortality, Walking, physiology |
| Progression of delirium in advanced illness: a multivariate model of caregiver and clinician perspectives. | Kerr CW, Donnelly JP, Wright ST, Luczkiewicz DL, McKenzie KJ, Hang PC, Kuszczak SM | Journal of palliative medicine | 2013 |
Aged, Aged, 80 and over, Attitude of Health Personnel, Caregivers, psychology, Confusion, Delirium, diagnosis, Disease Progression, Female, Hospice Care, Humans, Interviews as Topic, Male, Middle Aged, Multivariate Analysis, Observation, Palliative Care, manpower, Psychomotor Agitation, Qualitative Research, Sleep Disorders, Symptom Assessment, Terminally Ill, psychology |
| Complex assessment of the incidence and risk factors of delirium in a large cohort of cardiac surgery patients: a single-center 6-year experience. | Krzych LJ, Wybraniec MT, Krupka-Matuszczyk I, Skrzypek M, Bolkowska A, Wilczyński M, Bochenek AA | BioMed research international | 2013 |
Aged, Aged, 80 and over, Brain Ischemia, complications, Cardiac Surgical Procedures, adverse effects, Delirium, etiology, Female, Humans, Male, Postoperative Complications, etiology, Psychotropic Drugs, Risk Factors, Stroke, complications |
| An intermediate care unit for older people with both physical and psychiatric disorders: naturalistic outcome study. | Hilton C, Madaras A, Qureshi M | International psychogeriatrics / IPA | 2013 |
Activities of Daily Living, Aged, Aged, 80 and over, Delirium, psychology, Disabled Persons, psychology, Female, Humans, Intermediate Care Facilities, Length of Stay, statistics & numerical data, Logistic Models, Male, Outcome Assessment (Health Care), Patient Discharge, statistics & numerical data, Retrospective Studies |
| Use of a Geriatric Quality Initiative to Educate Internal Medicine Residents about Delirium and Its Risk Factors. | Olveczky D, Mattison ML, Mukamal KJ | Journal of graduate medical education | 2013 | |
| Quality improvement and cost savings with multicomponent delirium interventions: replication of the Hospital Elder Life Program in a community hospital. | Zaubler TS, Murphy K, Rizzuto L, Santos R, Skotzko C, Giordano J, Bustami R, Inouye SK | Psychosomatics | 2013 |
Aged, Aged, 80 and over, Chi-Square Distribution, Cost Savings, economics, Delirium, economics, Female, Geriatric Assessment, Health Services for the Aged, economics, Hospital Costs, statistics & numerical data, Hospitals, Community, Humans, Length of Stay, economics, Male, Outcome and Process Assessment (Health Care), statistics & numerical data, Program Evaluation, Quality Improvement, Statistics, Nonparametric |
| Hospital elder life program integrated in dutch hospital care: a pilot. | Bakker FC, Persoon A, Schoon Y, Olde Rikkert MG | Journal of the American Geriatrics Society | 2013 |
Aged, Delivery of Health Care, Integrated, methods, Feasibility Studies, Geriatric Assessment, methods, Health Services Needs and Demand, statistics & numerical data, Health Services for the Aged, organization & administration, Home Care Services, organization & administration, Hospitalization, statistics & numerical data, Humans, Middle Aged, Netherlands, Pilot Projects |
| Learning from the closure of clinical programs: a case series from the Hospital Elder Life Program. | SteelFisher GK, Martin LA, Dowal SL, Inouye SK | Journal of the American Geriatrics Society | 2013 |
Aged, Cost-Benefit Analysis, Geriatrics, organization & administration, Health Services for the Aged, organization & administration, Hospital Administration, Humans, Organizational Objectives, Program Evaluation, methods, Quality of Health Care, United States |
| Design and methods of the Hospital Elder Life Program (HELP), a multicomponent targeted intervention to prevent delirium in hospitalized older patients: efficacy and cost-effectiveness in Dutch health care. | Strijbos MJ, Steunenberg B, van der Mast RC, Inouye SK, Schuurmans MJ | BMC geriatrics | 2013 |
Aged, Aged, 80 and over, Cost-Benefit Analysis, economics, Delirium, economics, Delivery of Health Care, economics, Early Medical Intervention, economics, Female, Hospitalization, economics, Humans, Male, Netherlands, epidemiology, Treatment Outcome |
| Prediction of delirium after cardiac surgery and the use of a risk checklist. | Koster S, Hensens AG, Schuurmans MJ, van der Palen J | European journal of cardiovascular nursing : journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology | 2013 |
Aged, Aged, 80 and over, Cardiac Surgical Procedures, adverse effects, Checklist, Cohort Studies, Delirium, diagnosis, Depressive Disorder, complications, Female, Heart Diseases, complications, Humans, Internal-External Control, Male, Middle Aged, Predictive Value of Tests, Risk Factors, Somatoform Disorders, complications, Stress, Psychological, complications, Surgical Procedures, Elective, adverse effects |
| Symptoms of delirium predict incident delirium in older long-term care residents. | Cole MG, McCusker J, Voyer P, Monette J, Champoux N, Ciampi A, Vu M, Dyachenko A, Belzile E | International psychogeriatrics / IPA | 2013 |
Aged, Aged, 80 and over, Canada, epidemiology, Confusion, complications, Delirium, epidemiology, Dementia, complications, Female, Follow-Up Studies, Geriatric Assessment, statistics & numerical data, Humans, Incidence, Long-Term Care, Male, Predictive Value of Tests, Proportional Hazards Models, Prospective Studies, Residential Facilities, Risk Factors |
| Factors associated with onset of delirium among internal medicine inpatients in Spain. | Díez-Manglano J, Palazón-Fraile C, Diez-Massó F, Martínez-Álvarez R, Del Corral-Beamonte E, Carreño-Borrego P, Pueyo-Tejedor P, Gomes-Martín J | Nursing research | 2013 |
Age Factors, Aged, Aged, 80 and over, Delirium, epidemiology, Female, Hospital Units, Hospitalization, statistics & numerical data, Humans, Incidence, Internal Medicine, Male, Middle Aged, Retrospective Studies, Risk Factors, Spain, Urinary Catheterization |
| Evaluation of the prevalence and risk factors of delirium in cardiac surgery ICU. | Shadvar K, Baastani F, Mahmoodpoor A, Bilehjani E | Journal of cardiovascular and thoracic research | 2013 | |
| Delirium prevalence, incidence, and implications for screening in specialist palliative care inpatient settings: a systematic review. | Hosie A, Davidson PM, Agar M, Sanderson CR, Phillips J | Palliative medicine | 2013 |
Delirium, diagnosis, Humans, Incidence, Mass Screening, standards, Palliative Care, methods, Prevalence, Prospective Studies |
| Test accuracy of short screening tests for diagnosis of delirium or cognitive impairment in an acute stroke unit setting. | Lees R, Corbet S, Johnston C, Moffitt E, Shaw G, Quinn TJ | Stroke; a journal of cerebral circulation | 2013 |
Aged, Aged, 80 and over, Cognition Disorders, complications, Delirium, complications, Female, Glasgow Coma Scale, Hospital Units, Humans, Male, Mental Status Schedule, Middle Aged, Neuropsychological Tests, Predictive Value of Tests, Questionnaires, Reproducibility of Results, Sensitivity and Specificity, Stroke, complications |
| Subsyndromal delirium and its determinants in elderly patients hospitalized for acute medical illness. | Zuliani G, Bonetti F, Magon S, Prandini S, Sioulis F, D'Amato M, Zampi E, Gasperini B, Cherubini A | The journals of gerontology. Series A, Biological sciences and medical sciences | 2013 |
Acute Disease, Aged, Aged, 80 and over, Aging, blood, Case-Control Studies, Cognition, Delirium, blood, Female, Hospitalization, Humans, Italy, epidemiology, Male, Mental Status Schedule, Oxygen, blood, Prevalence, Risk Factors |
| Thirty-day prevalence of delirium among very old people: a population-based study of very old people living at home and in institutions. | Mathillas J, Olofsson B, Lövheim H, Gustafson Y | Archives of gerontology and geriatrics | 2013 |
Age Factors, Aged, 80 and over, psychology, Delirium, epidemiology, Dementia, epidemiology, Depression, epidemiology, Female, Finland, epidemiology, Health Status, Homes for the Aged, statistics & numerical data, Humans, Independent Living, psychology, Institutionalization, statistics & numerical data, Male, Neuropsychological Tests, Prevalence, Sweden, epidemiology |
| Association between leptin and delirium in elderly inpatients. | Sánchez JC, Ospina JP, González MI | Neuropsychiatric disease and treatment | 2013 | |
| Efficacy and safety of haloperidol versus atypical antipsychotic medications in the treatment of delirium. | Yoon HJ, Park KM, Choi WJ, Choi SH, Park JY, Kim JJ, Seok JH | BMC psychiatry | 2013 |
Aged, Antipsychotic Agents, adverse effects, Benzodiazepines, adverse effects, Delirium, drug therapy, Dibenzothiazepines, adverse effects, Female, Haloperidol, adverse effects, Humans, Male, Middle Aged, Prospective Studies, Risperidone, adverse effects, Treatment Outcome |
| Association between sedating medications and delirium in older inpatients. | Rothberg MB, Herzig SJ, Pekow PS, Avrunin J, Lagu T, Lindenauer PK | Journal of the American Geriatrics Society | 2013 |
Aged, Aged, 80 and over, Antipsychotic Agents, therapeutic use, Delirium, chemically induced, Drug Therapy, Combination, Female, Follow-Up Studies, Humans, Hypnotics and Sedatives, adverse effects, Inpatients, Male, Prevalence, Psychotic Disorders, drug therapy, Retrospective Studies, Risk Factors, United States, epidemiology |
| Effect of intravenous haloperidol on the duration of delirium and coma in critically ill patients (Hope-ICU): a randomised, double-blind, placebo-controlled trial. | Page VJ, Ely EW, Gates S, Zhao XB, Alce T, Shintani A, Jackson J, Perkins GD, McAuley DF | The Lancet. Respiratory medicine | 2013 | |
| Educational interventions to improve recognition of delirium: a systematic review. | Yanamadala M, Wieland D, Heflin MT | Journal of the American Geriatrics Society | 2013 |
Aged, Delirium, diagnosis, Health Personnel, education, Humans |
| Temperature variability during delirium in ICU patients: an observational study. | van der Kooi AW, Kappen TH, Raijmakers RJ, Zaal IJ, Slooter AJ | PloS one | 2013 | |
| Automatic delirium prediction system in a Korean surgical intensive care unit. | Oh SH, Park EJ, Jin Y, Piao J, Lee SM | Nursing in critical care | 2014 | |
| Neuropathogenesis of delirium: review of current etiologic theories and common pathways. | Maldonado JR | The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry | 2013 |
Acetylcholine, metabolism, Aging, Brain, immunology, Chronobiology Disorders, complications, Delirium, etiology, Dopamine, metabolism, Humans, Inflammation, metabolism, Neural Pathways, physiopathology, Oxidative Stress, physiology |
| A longitudinal study of delirium phenomenology indicates widespread neural dysfunction. | Leonard M, Adamis D, Saunders J, Trzepacz P, Meagher D | Palliative & supportive care | 2013 | |
| The pharmacologic treatment of intensive care unit delirium: a systematic review. | Bathula M, Gonzales JP | The Annals of pharmacotherapy | 2013 |
Antipsychotic Agents, therapeutic use, Delirium, drug therapy, Humans, Intensive Care Units |
| Outcome and quality of life in patients with postoperative delirium during an ICU stay following major surgery. | Abelha FJ, Luís C, Veiga D, Parente D, Fernandes V, Santos P, Botelho M, Santos A, Santos C | Critical care (London, England) | 2013 | |
| Preoperative cerebrospinal fluid cytokine levels and the risk of postoperative delirium in elderly hip fracture patients. | Westhoff D, Witlox J, Koenderman L, Kalisvaart KJ, de Jonghe JF, van Stijn MF, Houdijk AP, Hoogland IC, Maclullich AM, van Westerloo DJ, van de Beek D, Eikelenboom P, van Gool WA | Journal of neuroinflammation | 2013 |
Aged, Aged, 80 and over, Biological Markers, cerebrospinal fluid, Cytokines, cerebrospinal fluid, Delirium, cerebrospinal fluid, Double-Blind Method, Female, Hip Fractures, cerebrospinal fluid, Humans, Male, Postoperative Complications, cerebrospinal fluid, Randomized Controlled Trials as Topic, Risk Factors |
| Delirium in Australian hospitals: a prospective study. | Travers C, Byrne GJ, Pachana NA, Klein K, Gray L | Current gerontology and geriatrics research | 2013 | |
| Confusion assessment method: a systematic review and meta-analysis of diagnostic accuracy. | Shi Q, Warren L, Saposnik G, Macdermid JC | Neuropsychiatric disease and treatment | 2013 | |
| Long-term cognitive impairment after critical illness. | Pandharipande PP, Girard TD, Jackson JC, Morandi A, Thompson JL, Pun BT, Brummel NE, Hughes CG, Vasilevskis EE, Shintani AK, Moons KG, Geevarghese SK, Canonico A, Hopkins RO, Bernard GR, Dittus RS, Ely EW, | The New England journal of medicine | 2013 |
Aged, Cognition Disorders, etiology, Critical Illness, psychology, Delirium, complications, Executive Function, Female, Humans, Intensive Care Units, Linear Models, Male, Middle Aged, Prospective Studies, Respiratory Insufficiency, complications, Shock, complications |