Delirium Bibliography

Delirium Bibliography books graphicWhat is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!

How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.

Reference Information

Title
Enhancing European Management of Analgesia, Sedation, and Delirium: A Multinational, Prospective, Interventional Before-After Trial
Authors
Paul, N. Grunow, J. J. Rosenthal, M. Spies, C. D. Page, V. J. Hanison, J. Patel, B. Rosenberg, A. von Haken, R. Pietsch, U. Schrag, C. Waydhas, C. Schellongowski, P. Lobmeyr, E. Sander, M. Piper, S. K. Conway, D. Totzeck, A. Weiss, B.
Year
2024
Journal
Neurocrit Care
Abstract

BACKGROUND: The objective of this study was to analyze the impact of a structured educational intervention on the implementation of guideline-recommended pain, agitation, and delirium (PAD) assessment. METHODS: This was a prospective, multinational, interventional before-after trial conducted at 12 intensive care units from 10 centers in Germany, Austria, Switzerland, and the UK. Intensive care units underwent a 6-week structured educational program, comprising online lectures, instructional videos, educational handouts, and bedside teaching. Patient-level PAD assessment data were collected in three 1-day point-prevalence assessments before (T1), 6 weeks after (T2), and 1 year after (T3) the educational program. RESULTS: A total of 430 patients were included. The rate of patients who received all three PAD assessments changed from 55% (107/195) at T1 to 53% (68/129) at T2, but increased to 73% (77/106) at T3 (p = 0.003). The delirium screening rate increased from 64% (124/195) at T1 to 65% (84/129) at T2 and 77% (82/106) at T3 (p = 0.041). The pain assessment rate increased from 87% (170/195) at T1 to 92% (119/129) at T2 and 98% (104/106) at T3 (p = 0.005). The rate of sedation assessment showed no signficiant change. The proportion of patients who received nonpharmacological delirium prevention measures increased from 58% (114/195) at T1 to 80% (103/129) at T2 and 91% (96/106) at T3 (p < 0.001). Multivariable regression revealed that at T3, patients were more likely to receive a delirium assessment (odds ratio [OR] 2.138, 95% confidence interval [CI] 1.206-3.790; p = 0.009), sedation assessment (OR 4.131, 95% CI 1.372-12.438; p = 0.012), or all three PAD assessments (OR 2.295, 95% CI 1.349-3.903; p = 0.002) compared with T1. CONCLUSIONS: In routine care, many patients were not assessed for PAD. Assessment rates increased significantly 1 year after the intervention. Clinical trial registration ClinicalTrials.gov: NCT03553719.

PMID

PMID: 37697129

PMCID: PMC11147880

Keywords

Humans
*Delirium/therapy
Male
Female
Middle Aged
Aged
Prospective Studies
Pain Management/methods
Europe
Psychomotor Agitation/therapy
Germany
Austria
Adult
Analgesia/methods
Critical Care/standards
Switzerland
Intensive Care Units
United Kingdom
Pain Measurement
Conscious Sedation
Critical care
Delirium
Delivery of health care
Intensive care units

Page(s)
Issue

Search:
Total Records Found: 6080, showing 100 per page
TitleAuthorsJournalYearKeywords
Meta-analysis of factors which influence delirium following cardiac surgery. Lin Y, Chen J, Wang Z Journal of cardiac surgery 2012

Cardiac Surgical Procedures, Delirium, etiology, Humans, Postoperative Complications, etiology, Risk Factors

Delirium: An evidence-based medicine (EBM) monograph for psychosomatic medicine practice, comissioned by the Academy of Psychosomatic Medicine (APM) and the European Association of Consultation Liaison Psychiatry and Psychosomatics (EACLPP). Leentjens AF, Rundell J, Rummans T, Shim JJ, Oldham R, Peterson L, Philbrick K, Soellner W, Wolcott D, Freudenreich O Journal of psychosomatic research 2012

Delirium, diagnosis, Evidence-Based Medicine, Humans, Psychosomatic Medicine, Referral and Consultation

Symptom profile and etiology of delirium in a referral population in northern india: factor analysis of the DRS-R98. Mattoo SK, Grover S, Chakravarty K, Trzepacz PT, Meagher DJ, Gupta N The Journal of neuropsychiatry and clinical neurosciences 2012

Adolescent, Adult, Aged, Aged, 80 and over, Attention Deficit Disorder with Hyperactivity, etiology, Circadian Rhythm, physiology, Cognition Disorders, etiology, Delirium, complications, Diagnostic and Statistical Manual of Mental Disorders, Factor Analysis, Statistical, Female, Humans, India, epidemiology, Male, Middle Aged, Neuropsychological Tests, Perceptual Disorders, etiology, Psychiatric Status Rating Scales, Referral and Consultation, Severity of Illness Index, Sleep Disorders, etiology, Visual Perception, physiology, Young Adult

Delirium in acute stroke: screening tools, incidence rates and predictors: a systematic review. Carin-Levy G, Mead GE, Nicol K, Rush R, van Wijck F Journal of neurology 2012

Clinical Trials as Topic, methods, Delirium, diagnosis, Humans, Incidence, Predictive Value of Tests, Stroke, diagnosis

Endovascular versus open approach to aortic aneurysm repair surgery: rates of postoperative delirium. Salata K, Katznelson R, Beattie WS, Carroll J, Lindsay TF, Djaiani G Canadian journal of anaesthesia = Journal canadien d'anesthésie 2012

Age Factors, Aged, Aged, 80 and over, Aortic Aneurysm, Abdominal, surgery, Delirium, epidemiology, Endovascular Procedures, methods, Female, Hospitals, General, Humans, Length of Stay, Male, Middle Aged, Perioperative Care, methods, Postoperative Complications, epidemiology, Retrospective Studies, Time Factors

Ondasetron versus haloperidol for the treatment of postcardiotomy delirium: a prospective, randomized, double-blinded study. Tagarakis GI, Voucharas C, Tsolaki F, Daskalopoulos ME, Papaliagkas V, Parisis C, Gogaki E, Tsagalas I, Sataitidis I, Tsolaki M, Tsilimingas NB Journal of cardiothoracic surgery 2012

Aged, Aged, 80 and over, Analysis of Variance, Cardiac Surgical Procedures, adverse effects, Delirium, drug therapy, Double-Blind Method, Female, Haloperidol, therapeutic use, Humans, Male, Neuropsychological Tests, Ondansetron, therapeutic use, Postoperative Complications, drug therapy, Prospective Studies

Impact of a delirium screening tool and multifaceted education on nurses' knowledge of delirium and ability to evaluate it correctly. Gesin G, Russell BB, Lin AP, Norton HJ, Evans SL, Devlin JW American journal of critical care : an official publication, American Association of Critical-Care Nurses 2012

Adult, Checklist, Delirium, diagnosis, Female, Health Knowledge, Attitudes, Practice, Humans, Intensive Care Units, Male, Mass Screening, methods, Middle Aged, North Carolina, Nursing Staff, Hospital, education

Discharge diagnosis and comorbidity profile in hospitalized older patients with dementia. Zuliani G, Galvani M, Sioulis F, Bonetti F, Prandini S, Boari B, Guerzoni F, Gallerani M International journal of geriatric psychiatry 2012

Aged, Aged, 80 and over, Comorbidity, Dementia, diagnosis, Female, Hospital Mortality, Hospitalization, statistics & numerical data, Hospitals, University, statistics & numerical data, Humans, Italy, epidemiology, Length of Stay, Male, Odds Ratio, Patient Discharge, statistics & numerical data, Prevalence

The course of delirium in older long-term care residents. Cole MG, McCusker J, Voyer P, Monette J, Champoux N, Ciampi A, Vu M, Belzile E International journal of geriatric psychiatry 2012

Aged, 80 and over, Canada, epidemiology, Delirium, epidemiology, Disease Progression, Female, Humans, Incidence, Long-Term Care, statistics & numerical data, Male, Prospective Studies, Regression Analysis

The prevalence of mental health problems among older adults admitted as an emergency to a general hospital. Goldberg SE, Whittamore KH, Harwood RH, Bradshaw LE, Gladman JR, Jones RG, Age and ageing 2012

Aged, Aged, 80 and over, Anxiety, epidemiology, Delusions, epidemiology, Depression, epidemiology, Emergencies, epidemiology, Female, Geriatric Assessment, statistics & numerical data, Great Britain, epidemiology, Hallucinations, epidemiology, Hospitals, General, statistics & numerical data, Hospitals, Teaching, statistics & numerical data, Humans, Male, Mental Disorders, epidemiology, Patient Admission, statistics & numerical data, Prevalence

Psychiatric disorders in cancer patients at a university hospital in Japan: descriptive analysis of 765 psychiatric referrals. Tada Y, Matsubara M, Kawada S, Ishida M, Wada M, Wada T, Onishi H Japanese journal of clinical oncology 2012

Adolescent, Adult, Aged, Aged, 80 and over, Child, Female, Hospitals, University, Humans, Inpatients, statistics & numerical data, Japan, Male, Mental Disorders, epidemiology, Middle Aged, Neoplasms, complications, Outpatients, statistics & numerical data, Retrospective Studies, Young Adult

Validation of the Risk Model for Delirium in hip fracture patients. Moerman S, Tuinebreijer WE, de Boo M, Pilot P, Nelissen RG, Vochteloo AJ General hospital psychiatry 2012

Aged, Aged, 80 and over, Confidence Intervals, Delirium, epidemiology, Female, Hip Fractures, psychology, Humans, Logistic Models, Male, Models, Theoretical, Netherlands, Patients, psychology, Prospective Studies, ROC Curve, Risk Assessment, methods

A questionnaire survey of critical care nurses' attitudes to delirium assessment before and after introduction of the CAM-ICU. Eastwood GM, Peck L, Bellomo R, Baldwin I, Reade MC Australian critical care : official journal of the Confederation of Australian Critical Care Nurses 2012

Aged, Clinical Nursing Research, Critical Care, Delirium, diagnosis, Female, Health Knowledge, Attitudes, Practice, Humans, Intensive Care, methods, Intensive Care Units, Male, Mass Screening, methods, Middle Aged, Needs Assessment, organization & administration, Nursing Assessment, methods, Questionnaires

Apolipoprotein E e4 allele does not increase the risk of early postoperative delirium after major surgery. Abelha FJ, Fernandes V, Botelho M, Santos P, Santos A, Machado JC, Barros H Journal of anesthesia 2012

Postoperative delirium

APOE4

Surgery

PACU

APACHE II

SAPS II

Acute confusional state of unknown cause in the elderly: a study with continuous EEG monitoring. Naeije G, Gaspard N, Depondt C, Pepersack T, Legros B Epilepsy & behavior : E&B 2012

Aged, Aged, 80 and over, Anticonvulsants, therapeutic use, Cohort Studies, Confusion, diagnosis, Electroencephalography, Female, Humans, Male, Monitoring, Physiologic, Retrospective Studies

Towards a predictive model for post-stroke delirium. Kostalova M, Bednarik J, Mitasova A, Dušek L, Michalcakova R, Kerkovsky M, Kasparek T, Jezkova M, Balabanova P, Vohanka S Brain injury : [BI] 2012

Age Factors, Aged, Bilirubin, blood, C-Reactive Protein, metabolism, Cerebral Hemorrhage, blood, Delirium, blood, Diagnostic and Statistical Manual of Mental Disorders, Female, Humans, Male, Models, Theoretical, Predictive Value of Tests, Prognosis, Prospective Studies, Risk Factors, Stroke, blood, Survival Rate, Time Factors, gamma-Glutamyltransferase, blood

Neural network functional connectivity during and after an episode of delirium. Choi SH, Lee H, Chung TS, Park KM, Jung YC, Kim SI, Kim JJ The American journal of psychiatry 2012

Aged, Case-Control Studies, Delirium, etiology, Female, Functional Neuroimaging, Gyrus Cinguli, physiopathology, Humans, Magnetic Resonance Imaging, Male, Nerve Net, physiopathology, Prefrontal Cortex, physiopathology, Severity of Illness Index

Post-stroke delirium in relation to dementia and long-term mortality. Melkas S, Laurila JV, Vataja R, Oksala N, Jokinen H, Pohjasvaara T, Leppävuori A, Kaste M, Karhunen PJ, Erkinjuntti T International journal of geriatric psychiatry 2012

Aged, Aged, 80 and over, Cohort Studies, Delirium, epidemiology, Dementia, etiology, Educational Status, Female, Finland, epidemiology, Humans, Kaplan-Meier Estimate, Male, Middle Aged, Proportional Hazards Models, Risk Factors, Stroke, complications

Preoperative statin therapy is not associated with a decrease in the incidence of delirium after cardiac operations. Mariscalco G, Cottini M, Zanobini M, Salis S, Dominici C, Banach M, Onorati F, Piffaretti G, Covaia G, Realini M, Beghi C The Annals of thoracic surgery 2012

Age Factors, Aged, Cohort Studies, Confidence Intervals, Coronary Angiography, methods, Coronary Artery Bypass, adverse effects, Coronary Stenosis, drug therapy, Delirium, epidemiology, Female, Hospital Mortality, trends, Humans, Hydroxymethylglutaryl-CoA Reductase Inhibitors, administration & dosage, Incidence, Length of Stay, Male, Middle Aged, Multivariate Analysis, Odds Ratio, Postoperative Complications, epidemiology, Preoperative Care, methods, Retrospective Studies, Risk Assessment, Severity of Illness Index, Sex Factors

The effect of earplugs during the night on the onset of delirium and sleep perception: a randomized controlled trial in intensive care patients. Van Rompaey B, Elseviers MM, Van Drom W, Fromont V, Jorens PG Critical care (London, England) 2012

ICU delirium

Delirium

Earplugs

prevention

Sleep quality

NEECHAM

ICU delirium: an update. Jones SF, Pisani MA Current opinion in critical care 2012

Anesthesia, General, adverse effects, Antipsychotic Agents, therapeutic use, Critical Illness, Delirium, diagnosis, Female, Haloperidol, therapeutic use, Humans, Intensive Care, Intensive Care Units, Male, Risk Factors, Treatment Outcome

Incidence and short-term consequences of delirium in critically ill patients: A prospective observational cohort study. van den Boogaard M, Schoonhoven L, van der Hoeven JG, van Achterberg T, Pickkers P International journal of nursing studies 2012

Critical Illness, Delirium, epidemiology, Humans, Incidence, Prospective Studies

Pharmacological and nonpharmacological management of delirium in critically ill patients. Hipp DM, Ely EW Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2012

Analgesics, Non-Narcotic, therapeutic use, Antipsychotic Agents, therapeutic use, Critical Care, methods, Critical Illness, psychology, Delirium, therapy, Dexmedetomidine, therapeutic use, Humans, Respiration, Artificial, methods

The relation between atherosclerosis and the occurrence of postoperative delirium in vascular surgery patients. Pol RA, van Leeuwen BL, Reijnen MM, Zeebregts CJ Vascular medicine (London, England) 2012

Age Factors, Aged, Aged, 80 and over, Atherosclerosis, epidemiology, Cognition, Cognition Disorders, epidemiology, Comorbidity, Delirium, epidemiology, Female, Frail Elderly, Humans, Incidence, Inflammation, epidemiology, Male, Risk Assessment, Risk Factors, Smoking, epidemiology, Vascular Surgical Procedures, adverse effects

Delirium in acute stroke: a systematic review and meta-analysis. Shi Q, Presutti R, Selchen D, Saposnik G Stroke; a journal of cerebral circulation 2012

Aged, Data Interpretation, Statistical, Delirium, etiology, Female, Humans, Male, Middle Aged, Odds Ratio, Publication Bias, Reproducibility of Results, Risk, Stroke, complications, Treatment Outcome

Prospective cohort study of adverse events in older people admitted to the acute general hospital: risk factors and the impact of dementia. Watkin L, Blanchard MR, Tookman A, Sampson EL International journal of geriatric psychiatry 2012

Acute Disease, Aged, Aged, 80 and over, Cohort Studies, Delirium, epidemiology, Dementia, epidemiology, Female, Great Britain, epidemiology, Hospitals, General, statistics & numerical data, Humans, Male, Patient Safety, statistics & numerical data, Prospective Studies, Risk Factors

A longitudinal study of motor subtypes in delirium: frequency and stability during episodes. Meagher DJ, Leonard M, Donnelly S, Conroy M, Adamis D, Trzepacz PT Journal of psychosomatic research 2012

Aged, Aged, 80 and over, Cognition Disorders, epidemiology, Comorbidity, Delirium, classification, Diagnostic and Statistical Manual of Mental Disorders, Episode of Care, Female, Humans, Hyperkinesis, etiology, Hypokinesia, etiology, Intelligence Tests, Male, Middle Aged, Palliative Care, Psychiatric Status Rating Scales, Psychomotor Performance, classification, Psychophysiology, Research Design

Association between contact precautions and delirium at a tertiary care center. Day HR, Perencevich EN, Harris AD, Gruber-Baldini AL, Himelhoch SS, Brown CH, Dotter E, Morgan DJ Infection control and hospital epidemiology : the official journal of the Society of Hospital Epidemiologists of America 2012

Bacterial Infections, microbiology, Cross Infection, prevention & control, Delirium, epidemiology, Drug Resistance, Multiple, Bacterial, Gloves, Protective, Hospitalization, Humans, Infection Control, Male, Middle Aged, Odds Ratio, Patient Isolation, psychology, Retrospective Studies, Surgical Attire

Delirium in critically ill patients: impact on long-term health-related quality of life and cognitive functioning. van den Boogaard M, Schoonhoven L, Evers AW, van der Hoeven JG, van Achterberg T, Pickkers P Critical care medicine 2012

Aged, Aged, 80 and over, Cognition, Cognition Disorders, etiology, Critical Illness, psychology, Delirium, complications, Humans, Intensive Care Units, Middle Aged, Neuropsychological Tests, Prospective Studies, Quality of Life, psychology

Critical care nurses' role in implementing the "ABCDE bundle" into practice. Balas MC, Vasilevskis EE, Burke WJ, Boehm L, Pun BT, Olsen KM, Peitz GJ, Ely EW Critical care nurse 2012

Critical Care, methods, Delirium, nursing, Evidence-Based Nursing, organization & administration, Humans, Hypnotics and Sedatives, therapeutic use, Mobility Limitation, Nurse’s Role, Nursing Methodology Research, Nursing Staff, Hospital, organization & administration, Respiration, Artificial, nursing

A review of pharmacologic management and prevention strategies for delirium in the intensive care unit. Bledowski J, Trutia A Psychosomatics 2012

Adrenergic alpha-2 Receptor Agonists, pharmacology, Antipsychotic Agents, therapeutic use, Cholinesterase Inhibitors, pharmacology, Databases, Bibliographic, Delirium, drug therapy, Dexmedetomidine, pharmacology, Humans, Intensive Care, Intensive Care Units, statistics & numerical data, Neuroprotective Agents, therapeutic use, Prospective Studies, Randomized Controlled Trials as Topic, Treatment Outcome

The tryptophan depletion theory in delirium: not confirmed in elderly hip fracture patients. de Jonghe A, van Munster BC, Fekkes D, van Oosten HE, de Rooij SE Psychosomatics 2012

Aged, Aged, 80 and over, Analysis of Variance, Biological Markers, metabolism, Delirium, blood, Female, Hip Fractures, metabolism, Humans, Indoleamine-Pyrrole 2,3,-Dioxygenase, physiology, Kynurenine, blood, Linear Models, Male, Postoperative Period, Prospective Studies, Serotonin, biosynthesis, Tryptophan, blood

Preventing delirium in older adults with recent hip fracture through multidisciplinary geriatric consultation. Deschodt M, Braes T, Flamaing J, Detroyer E, Broos P, Haentjens P, Boonen S, Milisen K Journal of the American Geriatrics Society 2012

Activities of Daily Living, Aged, Aged, 80 and over, Belgium, epidemiology, Delirium, epidemiology, Female, Geriatric Assessment, Hip Fractures, surgery, Humans, Incidence, Male, Orthopedic Procedures, adverse effects, Postoperative Complications, Prognosis, Referral and Consultation, utilization

Early treatment with risperidone for subsyndromal delirium after on-pump cardiac surgery in the elderly: a randomized trial. Hakim SM, Othman AI, Naoum DO Anesthesiology 2012

Aged, Anesthesia, General, Antipsychotic Agents, adverse effects, Basal Ganglia Diseases, chemically induced, Cardiopulmonary Bypass, adverse effects, Delirium, drug therapy, Double-Blind Method, Female, Humans, Intensive Care, Length of Stay, Male, Neuropsychological Tests, Postoperative Care, Postoperative Complications, drug therapy, Psychiatric Status Rating Scales, Regression Analysis, Risperidone, adverse effects, Sample Size, Treatment Outcome

Preventing delirium in an acute hospital using a non-pharmacological intervention. Martinez FT, Tobar C, Beddings CI, Vallejo G, Fuentes P Age and ageing 2012

Aged, Aged, 80 and over, Delirium, epidemiology, Family Relations, Female, Humans, Inpatients, psychology, Male, Prognosis, Recognition (Psychology), Risk Factors, Single-Blind Method, Time Factors, Treatment Outcome, Visitors to Patients, psychology

High preoperative plasma neopterin predicts delirium after cardiac surgery in older adults. Osse RJ, Fekkes D, Tulen JH, Wierdsma AI, Bogers AJ, van der Mast RC, Hengeveld MW Journal of the American Geriatrics Society 2012

Aged, Biological Markers, blood, Cardiac Surgical Procedures, adverse effects, Chromatography, High Pressure Liquid, Delirium, blood, Female, Follow-Up Studies, Humans, Incidence, Male, Neopterin, blood, Netherlands, epidemiology, Postoperative Complications, Preoperative Period, Prognosis, Prospective Studies

The relationship between delirium duration, white matter integrity, and cognitive impairment in intensive care unit survivors as determined by diffusion tensor imaging: the VISIONS prospective cohort magnetic resonance imaging study*. Morandi A, Rogers BP, Gunther ML, Merkle K, Pandharipande P, Girard TD, Jackson JC, Thompson J, Shintani AK, Geevarghese S, Miller RR, Canonico A, Cannistraci CJ, Gore JC, Ely EW, Hopkins RO, Critical care medicine 2012

Aged, Anisotropy, Cognition Disorders, diagnosis, Corpus Callosum, pathology, Delirium, epidemiology, Diffusion Magnetic Resonance Imaging, Female, Follow-Up Studies, Humans, Imaging, Three-Dimensional, Intensive Care Units, Internal Capsule, pathology, Linear Models, Male, Middle Aged, Neuropsychological Tests, Pilot Projects, Prospective Studies, Sampling Studies, Survivors, Time Factors

Delirium screening in critically ill patients: a systematic review and meta-analysis. Neto AS, Nassar AP, Cardoso SO, Manetta JA, Pereira VG, Espósito DC, Damasceno MC, Slooter AJ Critical care medicine 2012

Critical Illness, Delirium, diagnosis, Humans, Intensive Care Units, Mass Screening, methods, Sensitivity and Specificity

Preoperative cognitive dysfunction is related to adverse postoperative outcomes in the elderly. Robinson TN, Wu DS, Pointer LF, Dunn CL, Moss M Journal of the American College of Surgeons 2012

Aged, Cognition Disorders, complications, Female, Humans, Incidence, Male, Postoperative Complications, epidemiology, Prospective Studies, Surgical Procedures, Elective

A survey of nurses' perceptions of the intensive care delirium screening checklist. Law TJ, Leistikow NA, Hoofring L, Krumm SK, Neufeld KJ, Needham DM Dynamics (Pembroke, Ont.) 2012

Checklist, Chi-Square Distribution, Delirium, diagnosis, Health Knowledge, Attitudes, Practice, Humans, Intensive Care, standards, Nursing Assessment, Questionnaires

A quality assurance study to assess the one-day prevalence of delirium in elderly hospitalized patients. McAiney CA, Patterson C, Coker E, Pizzacalla A Canadian geriatrics journal : CGJ 2012

acute care

delirium

education

elderly

healthcare providers

Daily sedation interruption in mechanically ventilated critically ill patients cared for with a sedation protocol: a randomized controlled trial. Mehta S, Burry L, Cook D, Fergusson D, Steinberg M, Granton J, Herridge M, Ferguson N, Devlin J, Tanios M, Dodek P, Fowler R, Burns K, Jacka M, Olafson K, Skrobik Y, Hébert P, Sabri E, Meade M, , JAMA : the journal of the American Medical Association 2012

Aged, Airway Extubation, Analgesics, Opioid, administration & dosage, Benzodiazepines, administration & dosage, Clinical Protocols, Conscious Sedation, methods, Critical Illness, Drug Administration Schedule, Female, Humans, Intensive Care Units, Male, Middle Aged, Respiration, Artificial, methods, Time Factors, Treatment Outcome

CAM-ICU and ICDSC agreement in medical and surgical ICU patients is influenced by disease severity. Fagundes JA, Tomasi CD, Giombelli VR, Alves SC, de Macedo RC, Topanotti MF, de Lourdes Ugioni Bristot M, do Brasil PE, Soares M, Salluh J, Dal-Pizzol F, Ritter C PloS one 2012

Adult, Checklist, Delirium, diagnosis, Female, Hospitalization, Humans, Intensive Care Units, Male, Middle Aged, Respiration, Artificial, Severity of Illness Index, Surgical Procedures, Operative

Symptoms of delirium occurring before and after episodes of delirium in older long-term care residents. Cole MG, McCusker J, Voyer P, Monette J, Champoux N, Ciampi A, Vu M, Dyachenko A, Belzile E Journal of the American Geriatrics Society 2012

Aged, 80 and over, Confusion, diagnosis, Delirium, diagnosis, Female, Humans, Long-Term Care, Male, Mental Status Schedule, Recurrence, Residential Facilities

Making decisions about delirium: a qualitative comparison of decision making between nurses working in palliative care, aged care, aged care psychiatry, and oncology. Agar M, Draper B, Phillips PA, Phillips J, Collier A, Harlum J, Currow D Palliative medicine 2012

Adult, Aged, Attitude of Health Personnel, Australia, Decision Making, Delirium, nursing, Female, Geriatric Nursing, Humans, Male, Middle Aged, Nursing Staff, psychology, Oncology Nursing, Palliative Care, Psychiatric Nursing, Qualitative Research, Young Adult

Symptom profile of postoperative delirium in patients with and without dementia. Lundström M, Stenvall M, Olofsson B Journal of geriatric psychiatry and neurology 2012

Aged, 80 and over, Circadian Rhythm, Delirium, complications, Dementia, complications, Female, Femoral Neck Fractures, psychology, Geriatric Assessment, methods, Humans, Male, Neuropsychological Tests, statistics & numerical data, Postoperative Complications, diagnosis

Comparison and agreement between the Richmond Agitation-Sedation Scale and the Riker Sedation-Agitation Scale in evaluating patients' eligibility for delirium assessment in the ICU. Khan BA, Guzman O, Campbell NL, Walroth T, Tricker J, Hui SL, Perkins A, Zawahiri M, Buckley JD, Farber MO, Ely W, Boustani MA Chest 2012

Adult, Aged, Cohort Studies, Consciousness, classification, Delirium, diagnosis, Diagnostic Techniques and Procedures, Female, Humans, Hypnotics and Sedatives, classification, Indiana, Intensive Care Units, Male, Mass Screening, methods, Middle Aged, Outcome Assessment (Health Care), Prospective Studies, Psychomotor Agitation, classification, Retrospective Studies

Screening for delirium within the interRAI acute care assessment system. Salih SA, Paul S, Klein K, Lakhan P, Gray L The journal of nutrition, health & aging 2012

Aged, Aged, 80 and over, Aging, Cohort Studies, Critical Care, methods, Delirium, diagnosis, Diagnostic and Statistical Manual of Mental Disorders, Female, Geriatric Assessment, methods, Hospitals, Urban, Humans, Male, Mass Screening, Nursing Staff, Hospital, education, Prevalence, Prospective Studies, Queensland, epidemiology, Sensitivity and Specificity, Speech Disorders, etiology, Tertiary Care Centers

Pharmacologic prevention and treatment of delirium in critically ill and non-critically ill hospitalised patients: a review of data from prospective, randomised studies. Devlin JW, Al-Qadhee NS, Skrobik Y Best practice & research. Clinical anaesthesiology 2012

Aged, Antipsychotic Agents, adverse effects, Critical Illness, Delirium, drug therapy, Dexmedetomidine, adverse effects, Hospitalization, Humans, Intensive Care Units, Outcome Assessment (Health Care), Randomized Controlled Trials as Topic, methods, Research Design

Screening for delirium using family caregivers: convergent validity of the Family Confusion Assessment Method and interviewer-rated Confusion Assessment Method. Steis MR, Evans L, Hirschman KB, Hanlon A, Fick DM, Flanagan N, Inouye SK Journal of the American Geriatrics Society 2012

Aged, Aged, 80 and over, Caregivers, Delirium, diagnosis, Female, Humans, Male, Psychiatric Status Rating Scales, Reproducibility of Results

Tools to detect delirium superimposed on dementia: a systematic review. Morandi A, McCurley J, Vasilevskis EE, Fick DM, Bellelli G, Lee P, Jackson JC, Shenkin SD, Marcotrabucchi , Schnelle J, Inouye SK, Ely EW, Ely WE, MacLullich A Journal of the American Geriatrics Society 2012

Adult, Aged, Aged, 80 and over, Delirium, complications, Dementia, complications, Diagnostic Techniques, Neurological, Humans, Middle Aged

Impaired cerebrovascular autoregulation in patients with severe sepsis and sepsis-associated delirium. Schramm P, Klein KU, Falkenberg L, Berres M, Closhen D, Werhahn KJ, David M, Werner C, Engelhard K Critical care (London, England) 2012

Sepsis-associated delirium

cerebrovascular autoregulation

delirium

ICU delirium

CAM-ICU

The association between brain volumes, delirium duration, and cognitive outcomes in intensive care unit survivors: the VISIONS cohort magnetic resonance imaging study*. Gunther ML, Morandi A, Krauskopf E, Pandharipande P, Girard TD, Jackson JC, Thompson J, Shintani AK, Geevarghese S, Miller RR, Canonico A, Merkle K, Cannistraci CJ, Rogers BP, Gatenby JC, Heckers S, Gore JC, Hopkins RO, Ely EW, Critical care medicine 2012

Age Factors, Aged, Atrophy, pathology, Attention, Brain, pathology, Cognition Disorders, diagnosis, Delirium, epidemiology, Diffusion Magnetic Resonance Imaging, Executive Function, Female, Follow-Up Studies, Humans, Intensive Care Units, Linear Models, Male, Middle Aged, Neuropsychological Tests, Prospective Studies, Sepsis, epidemiology, Survivors, Time Factors

The prevalence, incidence and risk factors for delirium in Dutch nursing homes and residential care homes. Boorsma M, Joling KJ, Frijters DH, Ribbe ME, Nijpels G, van Hout HP International journal of geriatric psychiatry 2012

Accidental Falls, Aged, Aged, 80 and over, Cohort Studies, Delirium, complications, Dementia, complications, Female, Humans, Incidence, Male, Multivariate Analysis, Netherlands, epidemiology, Nursing Homes, statistics & numerical data, Parkinson Disease, complications, Prevalence, Residential Facilities, statistics & numerical data, Restraint, Physical, Risk Factors

Derivation and validation of a clinical prediction rule for delirium in patients admitted to a medical ward: an observational study. Martinez JA, Belastegui A, Basabe I, Goicoechea X, Aguirre C, Lizeaga N, Urreta I, Emparanza JI BMJ open 2012

Delirium

clinical prediction rule

elderly

Drug therapy for delirium in terminally ill adult patients. Candy B, Jackson KC, Jones L, Leurent B, Tookman A, King M The Cochrane database of systematic reviews 2012

Adult, Antipsychotic Agents, therapeutic use, Chlorpromazine, therapeutic use, Delirium, drug therapy, Haloperidol, therapeutic use, Humans, Lorazepam, therapeutic use, Randomized Controlled Trials as Topic, Terminally Ill, psychology

Associations of markers of inflammation and coagulation with delirium during critical illness. Girard TD, Ware LB, Bernard GR, Pandharipande PP, Thompson JL, Shintani AK, Jackson JC, Dittus RS, Ely EW Intensive care medicine 2012

Aged, Biological Markers, Blood Coagulation Disorders, blood, Delirium, blood, Female, Humans, Inflammation, blood, Male, Middle Aged, Multivariate Analysis, Prospective Studies, Respiration, Artificial, Risk Factors

Potentially preventable complications of urinary tract infections, pressure areas, pneumonia, and delirium in hospitalised dementia patients: retrospective cohort study. Bail K, Berry H, Grealish L, Draper B, Karmel R, Gibson D, Peut A BMJ open 2013
Acute care for elders components of acute geriatric unit care: systematic descriptive review. Fox MT, Sidani S, Persaud M, Tregunno D, Maimets I, Brooks D, O'Brien K Journal of the American Geriatrics Society 2013

Aged, 80 and over, Critical Care, methods, Geriatric Assessment, Health Services for the Aged, organization & administration, Humans, Patient-Centered Care, organization & administration

Haloperidol overdosing in the treatment of agitated hospitalized older people with delirium: a retrospective chart review from a community teaching hospital. Zirker W, Dorokhine I, Knapp CM, Patel N, Musuku M Drugs & aging 2013

Aged, Aged, 80 and over, Aging, Anti-Anxiety Agents, administration & dosage, Delirium, drug therapy, Dopamine Antagonists, administration & dosage, Dose-Response Relationship, Drug, Drug Prescriptions, Drug Therapy, Combination, adverse effects, Female, GABA Modulators, administration & dosage, Haloperidol, administration & dosage, Hospitals, Community, Hospitals, Teaching, Humans, Length of Stay, Lorazepam, administration & dosage, Male, Medical Records, Pennsylvania, Physician’s Practice Patterns, Psychomotor Agitation, etiology, Retrospective Studies

A quality improvement program to increase nurses’ detection of delirium on an acute medical unit. Solberg LM, Plummer CE, May KN, Mion LC Geriatric nursing (New York, N.Y.) 2013

Aged, Aged, 80 and over, Delirium, diagnosis, Female, Hospital Units, Humans, Male, Nursing Diagnosis, Nursing Staff, Hospital, Quality Improvement

Evaluation of two delirium screening tools for detecting post-operative delirium in the elderly. Neufeld KJ, Leoutsakos JS, Sieber FE, Joshi D, Wanamaker BL, Rios-Robles J, Needham DM British journal of anaesthesia 2013

Aged, Aged, 80 and over, Anesthesia, General, Checklist, Delirium, diagnosis, Diagnostic and Statistical Manual of Mental Disorders, Female, Humans, Intensive Care, methods, Male, Mass Screening, methods, Neuropsychological Tests, Postoperative Care, methods, Postoperative Complications, diagnosis, Prospective Studies, Psychiatric Status Rating Scales, Sensitivity and Specificity

Does preoperative risk for delirium moderate the effects of postoperative pain and opiate use on postoperative delirium? Leung JM, Sands LP, Lim E, Tsai TL, Kinjo S The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2013
Clinical decision support system and incidence of delirium in cognitively impaired older adults transferred to intensive care. Khan BA, Calvo-Ayala E, Campbell N, Perkins A, Ionescu R, Tricker J, Campbell T, Zawahiri M, Buckley JD, Farber MO, Boustani MA American journal of critical care : an official publication, American Association of Critical-Care Nurses 2013

Aged, Cholinergic Antagonists, adverse effects, Cognition Disorders, complications, Decision Support Systems, Clinical, Delirium, epidemiology, Female, Hospitals, University, Hospitals, Urban, Humans, Incidence, Indiana, Intensive Care Units, Male, Medical Order Entry Systems, statistics & numerical data, Physician’s Practice Patterns, statistics & numerical data, Randomized Controlled Trials as Topic, Restraint, Physical, adverse effects, Risk Factors, Urinary Catheters, adverse effects

Delirium and cerebrospinal fluid S100B in hip fracture patients: a preliminary study. Hall RJ, Ferguson KJ, Andrews M, Green AJ, White TO, Armstrong IR, MacLullich AM The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2013

Aged, Aged, 80 and over, Biological Markers, cerebrospinal fluid, Delirium, cerebrospinal fluid, Female, Hip Fractures, complications, Humans, Male, S100 Calcium Binding Protein beta Subunit, cerebrospinal fluid

HELP© prevent falls by preventing delirium. Babine RL, Farrington S, Wierman HR Nursing 2013

Accidental Falls, prevention & control, Aged, Attitude of Health Personnel, Delirium, nursing, Geriatric Assessment, Geriatric Nursing, methods, Hospital Units, statistics & numerical data, Humans, Nursing Evaluation Research, Nursing Methodology Research, Nursing Staff, Hospital, education, Personal Satisfaction, Pilot Projects, Risk Factors, Risk Management, methods

The effect of a quality improvement intervention on perceived sleep quality and cognition in a medical ICU. Kamdar BB, King LM, Collop NA, Sakamuri S, Colantuoni E, Neufeld KJ, Bienvenu OJ, Rowden AM, Touradji P, Brower RG, Needham DM Critical care medicine 2013

Adult, Aged, Baltimore, Cognition, Delirium, physiopathology, Female, Humans, Intensive Care Units, Male, Middle Aged, Noise, Occupational, Outcome Assessment (Health Care), methods, Qualitative Research, Quality Improvement, Sleep

A prediction rule for the development of delirium among patients in medical wards: Chi-Square Automatic Interaction Detector (CHAID) decision tree analysis model. Kobayashi D, Takahashi O, Arioka H, Koga S, Fukui T The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2013
Environmental factors predict the severity of delirium symptoms in long-term care residents with and without delirium. McCusker J, Cole MG, Voyer P, Vu M, Ciampi A, Monette J, Champoux N, Belzile E, Dyachenko A Journal of the American Geriatrics Society 2013

Activities of Daily Living, Aged, Aged, 80 and over, Canada, Cohort Studies, Confusion, epidemiology, Delirium, epidemiology, Female, Health Status, Humans, Long-Term Care, Male, Mental Health, statistics & numerical data, Prospective Studies, Residential Facilities, organization & administration, Risk Factors, Severity of Illness Index, Social Environment

What do we really know about the treatment of delirium with antipsychotics? Ten key issues for delirium pharmacotherapy. Meagher DJ, McLoughlin L, Leonard M, Hannon N, Dunne C, O'Regan N The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2013

Antipsychotic Agents, therapeutic use, Delirium, drug therapy, Dose-Response Relationship, Drug, Haloperidol, therapeutic use, Humans, Risperidone, therapeutic use

A longitudinal study on delirium in nursing homes. von Gunten A, Mosimann UP, Antonietti JP The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2013
Delirium motor subtypes in elderly hip fracture patients: risk factors, outcomes and longitudinal stability. Slor CJ, Adamis D, Jansen RW, Meagher DJ, Witlox J, Houdijk AP, de Jonghe JF Journal of psychosomatic research 2013

APACHE, Activities of Daily Living, classification, Aged, 80 and over, Cohort Studies, Delirium, classification, Female, Hip Fractures, psychology, Humans, Longitudinal Studies, Male, Mental Status Schedule, Motor Activity, Netherlands, Postoperative Complications, classification, Prognosis, Prospective Studies, Risk Factors

Predicting delirium duration in elderly hip-surgery patients: does early symptom profile matter? Slor CJ, Witlox J, Adamis D, Meagher DJ, van der Ploeg T, Jansen RW, van Stijn MF, Houdijk AP, van Gool WA, Eikelenboom P, de Jonghe JF Current gerontology and geriatrics research 2013
Monitoring depth of anaesthesia in a randomized trial decreases the rate of postoperative delirium but not postoperative cognitive dysfunction. Radtke FM, Franck M, Lendner J, Krüger S, Wernecke KD, Spies CD British journal of anaesthesia 2013

Aged, Anesthesia, General, adverse effects, Anesthetics, General, administration & dosage, Cognition Disorders, etiology, Consciousness Monitors, Delirium, etiology, Double-Blind Method, Drug Administration Schedule, Electroencephalography, Female, Humans, Male, Middle Aged, Monitoring, Intraoperative, instrumentation, Neuropsychological Tests, Postoperative Complications, prevention & control, Prospective Studies

Management of delirium in medicine: experience of a Close Observation Unit. Eeles E, Thompson L, McCrow J, Pandy S Australasian journal on ageing 2013

Accidental Falls, prevention & control, Aged, Aged, 80 and over, Delirium, mortality, Female, Hospital Mortality, Humans, Length of Stay, Male

Functional improvement in hospitalized older adults is independent of dementia diagnosis: experience of a specialized delirium management unit. Bee Gek Tay L, Chew Chan MP, Sian Chong M Journal of hospital medicine : an official publication of the Society of Hospital Medicine 2013

Aged, Aged, 80 and over, Cohort Studies, Delirium, diagnosis, Dementia, diagnosis, Disease Management, Female, Hospital Units, trends, Hospitalization, trends, Humans, Male, Prospective Studies, Recovery of Function, physiology

Reliability of delirium rating scale (DRS) and delirium rating scale-revised-98 (DRS-R98) using variance-based multivariate modelling. Adamis D, Slor CJ, Leonard M, Witlox J, de Jonghe JF, Macdonald AJ, Trzepacz P, Meagher D Journal of psychiatric research 2013

Aged, Aged, 80 and over, Delirium, diagnosis, Female, Humans, Longitudinal Studies, Male, Models, Statistical, Observation, Psychiatric Status Rating Scales, Reproducibility of Results, Severity of Illness Index

Antipsychotic prophylaxis in surgical patients modestly decreases delirium incidence--but not duration--in high-incidence samples: a meta-analysis. Gilmore ML, Wolfe DJ General hospital psychiatry 2013

Aged, Aged, 80 and over, Antipsychotic Agents, therapeutic use, Benzodiazepines, therapeutic use, Chemoprevention, Delirium, prevention & control, Haloperidol, therapeutic use, Humans, Length of Stay, Middle Aged, Odds Ratio, Postoperative Complications, prevention & control, Randomized Controlled Trials as Topic, Risperidone, therapeutic use, Severity of Illness Index, Time Factors, Treatment Outcome

Prophylaxis with antipsychotic medication reduces the risk of post-operative delirium in elderly patients: a meta-analysis. Teslyar P, Stock VM, Wilk CM, Camsari U, Ehrenreich MJ, Himelhoch S Psychosomatics 2013

Aged, Antipsychotic Agents, administration & dosage, Delirium, epidemiology, Humans, Intensive Care Units, Length of Stay, Perioperative Care, methods, Placebos, Postoperative Complications, epidemiology, Randomized Controlled Trials as Topic, Risk, Surgical Procedures, Operative, adverse effects

Strategies for prevention of postoperative delirium: a systematic review and meta-analysis of randomized trials. Zhang H, Lu Y, Liu M, Zou Z, Wang L, Xu FY, Shi XY Critical care (London, England) 2013
The effect of poststroke delirium on short-term outcomes of elderly patients undergoing rehabilitation. Turco R, Bellelli G, Morandi A, Gentile S, Trabucchi M Journal of geriatric psychiatry and neurology 2013

Activities of Daily Living, Aged, 80 and over, Delirium, etiology, Female, Humans, Linear Models, Male, Neuropsychological Tests, Retrospective Studies, Stroke, complications, Treatment Outcome

Reducing deep sedation and delirium in acute lung injury patients: a quality improvement project. Hager DN, Dinglas VD, Subhas S, Rowden AM, Neufeld KJ, Bienvenu OJ, Touradji P, Colantuoni E, Reddy DR, Brower RG, Needham DM Critical care medicine 2013

Academic Medical Centers, Acute Lung Injury, etiology, Adult, Body Mass Index, Clinical Protocols, Comorbidity, Deep Sedation, methods, Delirium, diagnosis, Female, Humans, Inservice Training, Intensive Care Units, organization & administration, Male, Middle Aged, Quality Improvement, organization & administration, Respiration, Artificial, adverse effects, Socioeconomic Factors

Association between intraoperative blood transfusions and early postoperative delirium in older adults. Behrends M, DePalma G, Sands L, Leung J Journal of the American Geriatrics Society 2013

Aged, Aged, 80 and over, Blood Transfusion, adverse effects, Delirium, epidemiology, Female, Humans, Intraoperative Care, adverse effects, Logistic Models, Male, Multivariate Analysis, Prospective Studies, Risk Factors, San Francisco, epidemiology

In-facility delirium prevention programs as a patient safety strategy: a systematic review. Reston JT, Schoelles KM Annals of internal medicine 2013

Cost Savings, Delirium, prevention & control, Hospital Administration, Hospital Costs, Hospitals, standards, Humans, Long-Term Care, Palliative Care, Patient Safety, standards, Program Evaluation, Residential Facilities, economics, Risk Assessment, Risk Factors, Safety Management, organization & administration

Cortisol levels and neuropsychiatric diagnosis as markers of postoperative delirium: a prospective cohort study. Kazmierski J, Banys A, Latek J, Bourke J, Jaszewski R Critical care (London, England) 2013
Association of pre-operative brain pathology with post-operative delirium in a cohort of non-small cell lung cancer patients undergoing surgical resection. Root JC, Pryor KO, Downey R, Alici Y, Davis ML, Holodny A, Korc-Grodzicki B, Ahles T Psycho-oncology 2013

Aged, Aged, 80 and over, Analysis of Variance, Antipsychotic Agents, therapeutic use, Atrophy, pathology, Brain, pathology, Brain Diseases, complications, Carcinoma, Non-Small-Cell Lung, complications, Delirium, epidemiology, Female, Humans, Image Processing, Computer-Assisted, Lung Neoplasms, complications, Magnetic Resonance Imaging, Male, Middle Aged, Nerve Fibers, Myelinated, pathology, Pneumonectomy, Postoperative Complications, epidemiology, Retrospective Studies, Time-to-Treatment

The clinical and economic costs of delirium after surgical resection for esophageal malignancy. Markar SR, Smith IA, Karthikesalingam A, Low DE Annals of surgery 2013

Adult, Aged, Aged, 80 and over, Chemoradiotherapy, Chi-Square Distribution, Comorbidity, Delirium, economics, Esophageal Neoplasms, surgery, Esophagectomy, Female, Humans, Length of Stay, statistics & numerical data, Logistic Models, Male, Middle Aged, Neoadjuvant Therapy, Postoperative Complications, economics, Prospective Studies, Risk Assessment, Risk Factors, Statistics, Nonparametric, Survival Rate

Effects of routine monitoring of delirium in a surgical/trauma intensive care unit. Bigatello LM, Amirfarzan H, Haghighi AK, Newhouse B, Del Rio JM, Allen K, Chang A, Schmidt U, Razavi M The journal of trauma and acute care surgery 2013

Aged, Delirium, etiology, Female, Humans, Incidence, Intensive Care Units, Length of Stay, Male, Massachusetts, epidemiology, Middle Aged, Monitoring, Physiologic, methods, Postoperative Care, methods, Prevalence, Respiration, Artificial, Risk Factors, Trauma Centers, Wounds and Injuries, complications

Predisposing and precipitating factors of delirium after cardiac surgery: a prospective observational cohort study. Guenther U, Theuerkauf N, Frommann I, Brimmers K, Malik R, Stori S, Scheidemann M, Putensen C, Popp J Annals of surgery 2013

Age Factors, Aged, Cardiac Surgical Procedures, Cardiopulmonary Bypass, Chi-Square Distribution, Cognition Disorders, complications, Comorbidity, Delirium, etiology, Female, Humans, Intensive Care Units, Length of Stay, statistics & numerical data, Logistic Models, Male, Prospective Studies, Psychiatric Status Rating Scales, ROC Curve, Risk Factors, Sensitivity and Specificity, Systemic Inflammatory Response Syndrome, complications, Time Factors

The course of subsyndromal delirium in older long-term care residents. Cole MG, McCusker J, Voyer P, Monette J, Champoux N, Ciampi A, Vu M, Belzile E The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2013
Outcome after hepatectomy-delirium as an independent predictor for mortality. Veiga D, Luís C, Parente D, Abelha F BMC anesthesiology 2013
Factors predisposing to coma and delirium: fentanyl and midazolam exposure; CYP3A5, ABCB1, and ABCG2 genetic polymorphisms; and inflammatory factors. Skrobik Y, Leger C, Cossette M, Michaud V, Turgeon J Critical care medicine 2013

ATP-Binding Cassette Transporters, genetics, Coma, chemically induced, Critical Illness, Cytochrome P-450 CYP3A, genetics, Delirium, chemically induced, Dose-Response Relationship, Drug, Female, Fentanyl, administration & dosage, Humans, Hypnotics and Sedatives, administration & dosage, Inflammation, chemically induced, Intensive Care Units, Male, Midazolam, administration & dosage, Neoplasm Proteins, genetics, P-Glycoprotein, genetics, Polymorphism, Genetic, genetics

Risk and clinical-outcome indicators of delirium in an emergency department intermediate care unit (EDIMCU): an observational prospective study. Mariz J, Santos NC, Afonso H, Rodrigues P, Faria A, Sousa N, Teixeira J BMC emergency medicine 2013

Age Distribution, Aged, Comorbidity, Creatinine, blood, Delirium, diagnosis, Emergency Service, Hospital, Female, Hemoglobins, analysis, Hospital Mortality, Humans, Institutionalization, statistics & numerical data, Intermediate Care Facilities, Length of Stay, statistics & numerical data, Male, Middle Aged, Multivariate Analysis, Osmolar Concentration, Portugal, epidemiology, Prospective Studies, Systemic Inflammatory Response Syndrome, epidemiology, Urea, blood

α-Synuclein pathology is related to postoperative delirium in patients undergoing gastrectomy. Sunwoo MK, Hong JY, Choi J, Park HJ, Kim SH, Lee PH Neurology 2013

Aged, Delirium, etiology, Female, Gastrectomy, Humans, Male, Myenteric Plexus, metabolism, Postoperative Complications, physiopathology, Postoperative Period, Regression Analysis, Stomach Neoplasms, surgery, alpha-Synuclein, metabolism

Impact of delirium on clinical outcome in critically ill patients: a meta-analysis. Zhang Z, Pan L, Ni H General hospital psychiatry 2013

Aged, Critical Illness, Delirium, complications, Female, Hospital Mortality, Humans, Intensive Care Units, utilization, Length of Stay, Male, Middle Aged, Outcome Assessment (Health Care), Respiration, Artificial, utilization

Perioperative plasma melatonin concentration in postoperative critically ill patients: its association with delirium. Yoshitaka S, Egi M, Morimatsu H, Kanazawa T, Toda Y, Morita K Journal of critical care 2013

APACHE, Aged, Chi-Square Distribution, Comorbidity, Critical Illness, Delirium, blood, Female, Humans, Intensive Care Units, Male, Melatonin, blood, Middle Aged, Postoperative Period, Prospective Studies, Risk Factors, Statistics, Nonparametric

Fluctuations in sedation levels may contribute to delirium in ICU patients. Svenningsen H, Egerod I, Videbech P, Christensen D, Frydenberg M, Tønnesen EK Acta anaesthesiologica Scandinavica 2013

Aged, Analgesics, Opioid, adverse effects, Cohort Studies, Confusion, psychology, Conscious Sedation, Data Collection, Data Interpretation, Statistical, Delirium, etiology, Female, Humans, Hypnotics and Sedatives, administration & dosage, Intensive Care, Male, Midazolam, administration & dosage, Middle Aged, Odds Ratio, Patients, Prospective Studies, Psychomotor Agitation, diagnosis

Perioperative delirium and its relationship to dementia. Silverstein JH, Deiner SG Progress in neuro-psychopharmacology & biological psychiatry 2013

Anesthesia, adverse effects, Cognition Disorders, psychology, Delirium, psychology, Dementia, psychology, Disease Progression, Humans, Postoperative Complications, psychology, Risk Factors, Surgical Procedures, Operative, adverse effects

Sedation depth and long-term mortality in mechanically ventilated critically ill adults: a prospective longitudinal multicentre cohort study. Shehabi Y, Chan L, Kadiman S, Alias A, Ismail WN, Tan MA, Khoo TM, Ali SB, Saman MA, Shaltut A, Tan CC, Yong CY, Bailey M, Intensive care medicine 2013

APACHE, Chi-Square Distribution, Critical Illness, mortality, Deep Sedation, mortality, Delirium, diagnosis, Female, Humans, Hypnotics and Sedatives, administration & dosage, Intensive Care Units, Longitudinal Studies, Malaysia, epidemiology, Male, Middle Aged, Proportional Hazards Models, Prospective Studies, Respiration, Artificial

Delirium in an adult acute hospital population: predictors, prevalence and detection. Ryan DJ, O'Regan NA, Caoimh RÓ, Clare J, O'Connor M, Leonard M, McFarland J, Tighe S, O'Sullivan K, Trzepacz PT, Meagher D, Timmons S BMJ open 2013