What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Effect of electroencephalography-guided anesthetic administration on postoperative delirium among older adults undergoing major surgery the engages randomized clinical trial.
- Authors
- Wildes, T. S. Mickle, A. M. Abdallah, A. B. Maybrier, H. R. Oberhaus, J. Budelier, T. P. Kronzer, A. McKinnon, S. L. Park, D. Torres, B. A. Graetz, T. J. Emmert, D. A. Palanca, B. J. Goswami, S. Jordan, K. Lin, N. Fritz, B. A. Stevens, T. W. Jacobsohn, E.
- Year
- 2019
- Journal
- JAMA
- Abstract
IMPORTANCE Intraoperative electroencephalogram (EEG) waveform suppression, often suggesting excessive general anesthesia, has been associated with postoperative delirium. OBJECTIVE To assess whether EEG-guided anesthetic administration decreases the incidence of postoperative delirium. DESIGN, SETTING, AND PARTICIPANTS Randomized clinical trial of 1232 adults aged60years and older undergoing major surgery and receiving general anesthesia at Barnes-Jewish Hospital in St Louis. Recruitmentwas from January 2015 toMay 2018, with follow-up until July 2018. INTERVENTIONS Patients were randomized 1:1 (stratified by cardiac vs noncardiac surgery and positive vs negative recent fall history) to receive EEG-guided anesthetic administration (n = 614) or usual anesthetic care (n = 618). MAIN OUTCOMES AND MEASURES The primary outcomewas incident delirium during postoperative days 1 through 5. Intraoperative measures included anesthetic concentration, EEG suppression, and hypotension. Adverse events included undesirable intraoperative movement, intraoperative awareness with recall, postoperative nausea and vomiting, medical complications, and death. RESULTS Of the 1232 randomized patients (median age, 69 years [range, 60to 95]; 563women [45.7%]), 1213 (98.5%)were assessed for the primary outcome. Delirium during postoperative days 1 to 5 occurred in 157 of 604patients (26.0%)in the guided group and 140 of 609 patients (23.0%)in the usual care group (difference, 3.0%[95%CI, -2.0%to 8.0%]; P = .22). Median end-tidal volatile anesthetic concentrationwas significantly lower in the guided group than the usual care group (0.69 vs0.80minimum alveolar concentration; difference, -0.11 [95%CI, -0.13 to -0.10), and median cumulative time with EEGsuppressionwas significantly less (7 vs 13 minutes; difference, -6.0[95%CI, -9.9 to -2.1]). Therewas no significant difference between groups in the median cumulative time with mean arterial pressure below60mmHg (7 vs 7 minutes; difference,0.0[95%CI, -1.7 to 1.7]). Undesirablemovement occurred in 137 patients (22.3%) in the guided and 95 (15.4%) in the usual care group.Nopatients reported intraoperative awareness. Postoperative nausea and vomitingwas reported in 48 patients (7.8%) in the guided and 55 patients (8.9%) in the usual care group. Serious adverse eventswere reported in 124 patients (20.2%) in the guided and 130 (21.0%)in the usual care group. Within 30 days of surgery, 4 patients (0.65%) in the guided group and 19 (3.07%) in the usual care group died. CONCLUSIONS AND RELEVANCE Among older adults undergoing major surgery, EEG-guided anesthetic administration, compared with usual care, did not decrease the incidence of postoperative delirium. This finding does not support the use of EEG-guided anesthetic administration for this indication.
- PMID
- Keywords
NCT02241655
NCT02692300
bispectral index monitor
Quatro
anesthetic agent
adult
aged
anesthesia induction
article
awareness
bispectral index
body movement
Confusion Assessment Method
controlled study
double blind procedure
electroencephalography
falling
female
follow up
general anesthesia
heart surgery
human
hypotension
incidence
intermethod comparison
intraoperative period
major clinical study
major surgery
male
mean arterial pressure
mental disease assessment
middle aged
minimum lung alveolus concentration
Missouri
outcome assessment
postoperative complication
postoperative delirium
postoperative nausea and vomiting
postoperative period
priority journal
randomized controlled trial
recall
surgical mortality
very elderly
waveform
- Page(s)
- 473-83
- Volume
- 321
- Issue
- 5
Title | Authors | Journal | Year | Keywords |
---|---|---|---|---|
An epidemiological study of falls on integrated general medical wards. | Vassallo M, Azeem T, Pirwani MF, Sharma JC, Allen SC | International journal of clinical practice | 2000 |
Accidental Falls, prevention & control, Aged, Female, Hospitalization, statistics & numerical data, Humans, Male, Middle Aged, Patients’ Rooms, statistics & numerical data, Prospective Studies, Risk Factors |
Falls on integrated medical wards. | Vassallo M, Amersey RA, Sharma JC, Allen SC | Gerontology | 2000 |
Accidental Falls, statistics & numerical data, Age Distribution, Aged, Aged, 80 and over, Data Collection, Female, Great Britain, epidemiology, Hospital Departments, statistics & numerical data, Humans, Incidence, Male, Probability, Prospective Studies, Risk Factors, Sex Distribution, Wounds and Injuries, epidemiology |
Survival in end-stage dementia following acute illness. | Morrison RS, Siu AL | JAMA : the journal of the American Medical Association | 2000 |
Acute Disease, Advance Directives, Aged, Aged, 80 and over, Cognition, Cost of Illness, Dementia, complications, Female, Hip Fractures, complications, Hospitalization, Humans, Male, Palliative Care, Patient Care, Pneumonia, complications, Prognosis, Proportional Hazards Models, Prospective Studies, Survival Analysis |
Delirium in terminal cancer: a prospective study using daily screening, early diagnosis, and continuous monitoring. | Gagnon P, Allard P, Mâsse B, DeSerres M | Journal of pain and symptom management | 2000 |
Aged, Canada, Critical Illness, psychology, Delirium, epidemiology, Female, Humans, Incidence, Male, Neoplasms, psychology, Prospective Studies |
Impact of delirium on the short term prognosis of advanced cancer patients. Italian Multicenter Study Group on Palliative Care. | Caraceni A, Nanni O, Maltoni M, Piva L, Indelli M, Arnoldi E, Monti M, Montanari L, Amadori D, De Conno F | Cancer | 2000 |
Adolescent, Adult, Aged, Delirium, etiology, Female, Humans, Male, Middle Aged, Multicenter Studies as Topic, Neoplasms, diagnosis, Palliative Care, Prognosis, Prospective Studies, Survival Analysis |
Outcomes associated with delirium in acutely hospitalized acquired immune deficiency syndrome patients. | Uldall KK, Harris VL, Lalonde B | Comprehensive psychiatry | 2000 |
Acquired Immunodeficiency Syndrome, complications, Adult, Delirium, etiology, Female, HIV Infections, complications, Humans, Length of Stay, Male, Prognosis, Prospective Studies, Treatment Outcome, United States, epidemiology |
Association between delirium and death in AIDS patients. | Uldall KK, Ryan R, Berghuis JP, Harris VL | AIDS patient care and STDs | 2000 |
Acquired Immunodeficiency Syndrome, complications, Adult, Delirium, complications, Female, Humans, Length of Stay, Male, Medical Records, Middle Aged, Retrospective Studies, Severity of Illness Index, Survival Analysis, Washington, epidemiology |
Temporal association between hospitalization and rate of falls after discharge. | Mahoney JE, Palta M, Johnson J, Jalaluddin M, Gray S, Park S, Sager M | Archives of internal medicine | 2000 |
Accidental Falls, statistics & numerical data, Activities of Daily Living, classification, Acute Disease, Aged, Aged, 80 and over, Female, Geriatric Assessment, statistics & numerical data, Hospitalization, statistics & numerical data, Humans, Male, Patient Discharge, statistics & numerical data, Risk Factors, Time Factors, Wisconsin, epidemiology, Wounds and Injuries, epidemiology |
Consequences of not recognizing delirium superimposed on dementia in hospitalized elderly individuals. | Fick D, Foreman M | Journal of gerontological nursing | 2000 |
Activities of Daily Living, Aged, Aged, 80 and over, Comorbidity, Delirium, complications, Dementia, complications, Female, Geriatric Assessment, Geriatric Nursing, methods, Hospitalization, Humans, Incidence, Male, Mental Status Schedule, Nursing Assessment, methods, Prevalence |
The impact of delirium in the intensive care unit on hospital length of stay. | Ely EW, Gautam S, Margolin R, Francis J, May L, Speroff T, Truman B, Dittus R, Bernard R, Inouye SK | Intensive care medicine | 2001 |
Delirium, diagnosis, Female, Humans, Intensive Care Units, Length of Stay, Linear Models, Male, Middle Aged, Multivariate Analysis, Prospective Studies, Risk Factors, Survival Rate, Treatment Outcome |
What does the medical record reveal about functional status? A comparison of medical record and interview data. | Bogardus ST, Towle V, Williams CS, Desai MM, Inouye SK | Journal of general internal medicine | 2001 |
Academic Medical Centers, Activities of Daily Living, Aged, Aged, 80 and over, Female, Health Status, Humans, Interviews as Topic, Male, Medical Records, Outcome Assessment (Health Care), Predictive Value of Tests, Sensitivity and Specificity |
An algorithm for prospective individual matching in a non-randomized clinical trial. | Charpentier PA, Bogardus ST, Inouye SK | Journal of clinical epidemiology | 2001 |
Aged, Algorithms, Clinical Trials as Topic, Delirium, prevention & control, Female, Humans, Male, Risk Factors, Selection Bias |
Dementia and race: are there differences between African Americans and Caucasians? | Froehlich TE, Bogardus ST, Inouye SK | Journal of the American Geriatrics Society | 2001 |
African Continental Ancestry Group, Alzheimer Disease, epidemiology, Dementia, epidemiology, Dementia, Vascular, epidemiology, European Continental Ancestry Group, Humans, Prevalence, United States, epidemiology |
Risk adjustment for older hospitalized persons: a comparison of two methods of data collection for the Charlson index. | van Doorn C, Bogardus ST, Williams CS, Concato J, Towle VR, Inouye SK | Journal of clinical epidemiology | 2001 |
Aged, Comorbidity, Data Collection, methods, Female, Hospitalization, statistics & numerical data, Humans, Male, Mortality, Predictive Value of Tests, Prospective Studies, Risk Adjustment |
Cognitive and other adverse effects of diphenhydramine use in hospitalized older patients. | Agostini JV, Leo-Summers LS, Inouye SK | Archives of internal medicine | 2001 |
Aged, Aged, 80 and over, Cohort Studies, Connecticut, Delirium, chemically induced, Diphenhydramine, adverse effects, Female, Geriatric Assessment, Hospitalization, Hospitals, University, Humans, Male, Mental Status Schedule, Prospective Studies, Risk |
Acute confusional state in elderly orthopaedic patients: factors of importance for detection in nursing care. | Andersson EM, Gustafson L, Hallberg IR | International journal of geriatric psychiatry | 2001 |
Aged, Aged, 80 and over, Confusion, etiology, Cross-Sectional Studies, Emergency Service, Hospital, Female, Geriatric Assessment, Health Status, Hip Fractures, complications, Humans, Male, Nursing Homes, Postoperative Complications, Prognosis, Risk Factors |
An evidence-based clinical approach to the diagnosis of dementia. | Chong MS, Sahadevan S | Annals of the Academy of Medicine, Singapore | 2003 |
Alzheimer Disease, diagnosis, Brain, pathology, Caregivers, Delirium, diagnosis, Dementia, diagnosis, Dementia, Vascular, diagnosis, Evidence-Based Medicine, Health Status Indicators, Humans, Magnetic Resonance Imaging, Neuropsychological Tests, Tomography, X-Ray Computed |
The prognostic significance of subsyndromal delirium in elderly medical inpatients. | Cole M, McCusker J, Dendukuri N, Han L | Journal of the American Geriatrics Society | 2003 |
Aged, Aged, 80 and over, Cohort Studies, Cost of Illness, Delirium, diagnosis, Female, Health Status, Humans, Length of Stay, Male, Prognosis |
An empirical study of different diagnostic criteria for delirium among elderly medical inpatients. | Cole MG, Dendukuri N, McCusker J, Han L | The Journal of neuropsychiatry and clinical neurosciences | 2003 |
Aged, Aged, 80 and over, Confusion, epidemiology, Delirium, diagnosis, Dementia, diagnosis, Diagnosis, Differential, Diagnostic and Statistical Manual of Mental Disorders, Empirical Research, Female, Geriatric Assessment, Humans, Inpatients, International Classification of Diseases, standards, Male, Prospective Studies, Psychiatric Status Rating Scales, standards, Randomized Controlled Trials as Topic, statistics & numerical data, Reproducibility of Results, Sensitivity and Specificity |
Delirium in the course of cancer treatment. | Fann JR, Sullivan AK | Seminars in clinical neuropsychiatry | 2003 |
Analgesics, Opioid, adverse effects, Delirium, diagnosis, Hematopoietic Stem Cell Transplantation, adverse effects, Humans, Immunotherapy, adverse effects, Neoplasms, complications, Pain, drug therapy, Risk Factors, Terminal Care |
A model for managing delirious older inpatients. | Flaherty JH, Tariq SH, Raghavan S, Bakshi S, Moinuddin A, Morley JE | Journal of the American Geriatrics Society | 2003 |
Aged, Aged, 80 and over, Delirium, economics, Geriatric Nursing, economics, Health Facility Environment, economics, Hospital Units, economics, Humans, Intensive Care, economics, Mental Health Services, economics, Models, Nursing, Models, Organizational, Program Development, economics |
Donepezil for postoperative delirium. | Gleason OC | Psychosomatics | 2003 |
Aged, Arthroplasty, Replacement, Hip, Delirium, diagnosis, Female, Hip Fractures, surgery, Humans, Indans, therapeutic use, Mental Status Schedule, Nootropic Agents, therapeutic use, Piperidines, therapeutic use, Postoperative Complications, diagnosis, Treatment Outcome |
Cognitive impairment in hip fracture patients: timing of detection and longitudinal follow-up. | Gruber-Baldini AL, Zimmerman S, Morrison RS, Grattan LM, Hebel JR, Dolan MM, Hawkes W, Magaziner J | Journal of the American Geriatrics Society | 2003 |
Activities of Daily Living, Age Factors, Aged, Aged, 80 and over, Cognition Disorders, complications, Cohort Studies, Delirium, complications, Dementia, complications, Female, Follow-Up Studies, Hip Fractures, complications, Hospitalization, Humans, Incidence, Longitudinal Studies, Male, Prevalence, Psychiatric Status Rating Scales, Regression Analysis, Sex Factors, Time Factors |
Delirium in older emergency department patients discharged home: effect on survival. | Kakuma R, du Fort GG, Arsenault L, Perrault A, Platt RW, Monette J, Moride Y, Wolfson C | Journal of the American Geriatrics Society | 2003 |
Aged, Aged, 80 and over, Comorbidity, Delirium, complications, Emergency Service, Hospital, statistics & numerical data, Female, Humans, Male, Mortality, Patient Discharge, Prognosis, Prospective Studies, Quebec |
Delirium among newly admitted postacute facility patients: prevalence, symptoms, and severity. | Kiely DK, Bergmann MA, Murphy KM, Jones RN, Orav EJ, Marcantonio ER | The journals of gerontology. Series A, Biological sciences and medical sciences | 2003 |
Aged, Aged, 80 and over, Boston, epidemiology, Delirium, diagnosis, Female, Humans, Male, Prevalence, Skilled Nursing Facilities |
Delirium in the critical care patient: what the professional staff needs to know. | Litton KA | Critical care nursing quarterly | 2003 |
Aged, Alcohol Withdrawal Delirium, etiology, Anxiety, etiology, Comorbidity, Confusion, etiology, Critical Care, Delirium, diagnosis, Education, Continuing, Humans, Nurse’s Role, Nursing Assessment, Psychotic Disorders, etiology, Risk Factors |
Dementia after delirium in patients with femoral neck fractures. | Lundström M, Edlund A, Bucht G, Karlsson S, Gustafson Y | Journal of the American Geriatrics Society | 2003 |
Aged, Aged, 80 and over, Delirium, complications, Dementia, etiology, Female, Femoral Neck Fractures, complications, Follow-Up Studies, Humans, Male, Outcome Assessment (Health Care), Postoperative Period, Preoperative Care, Prospective Studies, Psychiatric Status Rating Scales, Risk Assessment, Time Factors |
Delirium symptoms in post-acute care: prevalent, persistent, and associated with poor functional recovery. | Marcantonio ER, Simon SE, Bergmann MA, Jones RN, Murphy KM, Morris JN | Journal of the American Geriatrics Society | 2003 |
Activities of Daily Living, Aged, Aged, 80 and over, Delirium, complications, Female, Humans, Male, Prevalence, Prospective Studies, Recovery of Function, Skilled Nursing Facilities, United States, epidemiology |
Delirium in the intensive care unit. | Marshall MC, Soucy MD | Critical care nursing quarterly | 2003 |
Aged, Anxiety, complications, Confusion, complications, Delirium, etiology, Dementia, complications, Humans, Intensive Care, Intensive Care Units, Mental Disorders, complications, Nursing Assessment, Psychomotor Agitation, complications, Risk Factors |
Detecting acute confusion in older adults: Comparing clinical reasoning of nurses working in acute, long-term, and community health care environments. | McCarthy MC | Research in nursing & health | 2003 |
Acute Disease, Aged, Clinical Competence, Confusion, diagnosis, Delirium, diagnosis, Dementia, diagnosis, Diagnosis, Differential, Health Facility Environment, Home Care Services, Homes for the Aged, Hospitals, Humans, Nursing Assessment, Nursing Homes, Ohio, Qualitative Research |
Delirium: elders tell their stories and guide nursing practice. | McCurren C, Cronin SN | Medsurg nursing : official journal of the Academy of Medical-Surgical Nurses | 2003 |
Aged, Aged, 80 and over, Delirium, nursing, Female, Humans, Life Change Events, Male, Nursing Assessment, Philosophy, Nursing, Questionnaires |
Does delirium increase hospital stay? | McCusker J, Cole MG, Dendukuri N, Belzile E | Journal of the American Geriatrics Society | 2003 |
Aged, Aged, 80 and over, Cohort Studies, Delirium, diagnosis, Female, Geriatric Assessment, Humans, Length of Stay, statistics & numerical data, Linear Models, Male, Prospective Studies, Quebec, epidemiology, Severity of Illness Index |
Delirium, depression, and anxiety. | Misra S, Ganzini L | Critical care clinics | 2003 |
Anxiety, diagnosis, Causality, Delirium, diagnosis, Depression, diagnosis, Humans, Incidence, Intensive Care, Prevalence, Risk Factors, Treatment Outcome |
Impaired communication capacity and agitated delirium in the final week of terminally ill cancer patients: prevalence and identification of research focus. | Morita T, Tei Y, Inoue S | Journal of pain and symptom management | 2003 |
Aged, Communication, Critical Illness, psychology, Delirium, epidemiology, Female, Humans, Male, Middle Aged, Prevalence, Research, Retrospective Studies |
Relationship between pain and opioid analgesics on the development of delirium following hip fracture. | Morrison RS, Magaziner J, Gilbert M, Koval KJ, McLaughlin MA, Orosz G, Strauss E, Siu AL | The journals of gerontology. Series A, Biological sciences and medical sciences | 2003 |
Aged, Aged, 80 and over, Analgesics, Opioid, administration & dosage, Cohort Studies, Confidence Intervals, Delirium, epidemiology, Dose-Response Relationship, Drug, Female, Follow-Up Studies, Hip Fractures, diagnosis, Humans, Incidence, Logistic Models, Male, Middle Aged, Multicenter Studies as Topic, Multivariate Analysis, New York City, Pain, diagnosis, Pain Measurement, Postoperative Period, Preoperative Care, Probability, Prospective Studies, Risk Assessment, Severity of Illness Index |
Identification and management of delirium in the critically ill patient with cancer. | Morrison C | AACN clinical issues | 2003 |
Anti-Anxiety Agents, therapeutic use, Antipsychotic Agents, therapeutic use, Benzodiazepines, Delirium, diagnosis, Diagnosis, Differential, Humans, Mental Disorders, diagnosis, Neoplasms, complications, Risk Factors, Terminology as Topic |
Delirium, depression often overlooked. | Naylor M | The American journal of nursing | 2003 |
Aged, Delirium, complications, Dementia, complications, Depression, complications, Hospitalization, Humans, Pilot Projects, United States |
Donepezil for anticholinergic drug intoxication: a case report. | Noyan MA, Elbi H, Aksu H | Progress in neuro-psychopharmacology & biological psychiatry | 2003 |
Amitriptyline, adverse effects, Cholinergic Antagonists, adverse effects, Delirium, chemically induced, Drug Overdose, Humans, Indans, therapeutic use, Male, Middle Aged, Piperidines, therapeutic use |
A patient with lithium intoxication developing at therapeutic serum lithium levels and persistent delirium after discontinuation of its administration. | Omata N, Murata T, Omori M, Wada Y | General hospital psychiatry | 2003 |
Antipsychotic Agents, adverse effects, Delirium, drug therapy, Drug Administration Schedule, Humans, Lithium Carbonate, adverse effects, Male, Middle Aged, Time Factors |
Excited delirium: does it exist? | Paquette M | Perspectives in psychiatric care | 2003 |
Death, Sudden, Delirium, complications, Humans, Police, Psychomotor Agitation, complications, Restraint, Physical, Violence, prevention & control |
A prospective, open-label, flexible-dose study of quetiapine in the treatment of delirium. | Sasaki Y, Matsuyama T, Inoue S, Sunami T, Inoue T, Denda K, Koyama T | The Journal of clinical psychiatry | 2003 |
Aged, Aged, 80 and over, Antipsychotic Agents, adverse effects, Delirium, drug therapy, Dibenzothiazepines, adverse effects, Dose-Response Relationship, Drug, Female, Humans, Male, Middle Aged, Treatment Outcome |
The Delirium Observation Screening Scale: a screening instrument for delirium. | Schuurmans MJ, Shortridge-Baggett LM, Duursma SA | Research and theory for nursing practice | 2003 |
Activities of Daily Living, Aged, Aged, 80 and over, Case-Control Studies, Delirium, diagnosis, Female, Geriatric Assessment, Humans, Male, Mass Screening, methods, Mental Status Schedule, Nursing Assessment, methods, Nursing Evaluation Research, Observation, methods, Prospective Studies, Psychometrics, Questionnaires, Risk Factors, Sensitivity and Specificity |
Delirium in adults with intellectual disabilities and DC-LD. | Simpson N | Journal of intellectual disability research : JIDR | 2003 |
Aged, Aged, 80 and over, Delirium, complications, Diagnostic and Statistical Manual of Mental Disorders, Female, Humans, Intellectual Disability, complications, Male |
Do guidelines improve the process and outcomes of care in delirium? | Young LJ, George J | Age and ageing | 2003 |
Aged, Delirium, diagnosis, Education, Medical, Continuing, Education, Nursing, Continuing, England, Geriatric Assessment, Geriatrics, education, Hospitals, General, standards, Humans, Mental Status Schedule, Outcome and Process Assessment (Health Care), Patient Care Planning, Practice Guidelines as Topic, Scotland |
Association between cardiac and noncardiac complications in patients undergoing noncardiac surgery: outcomes and effects on length of stay. | Fleischmann KE, Goldman L, Young B, Lee TH | The American journal of medicine | 2003 |
Aged, Female, Heart Diseases, epidemiology, Humans, Length of Stay, statistics & numerical data, Linear Models, Logistic Models, Male, Myocardial Infarction, epidemiology, Odds Ratio, Postoperative Complications, classification, Prospective Studies, Pulmonary Edema, epidemiology, Risk Factors |
Risk for acute confusion in sensory-impaired, rural, long-term-care elders. | Cacchione PZ, Culp K, Dyck MJ, Laing J | Clinical nursing research | 2003 |
Acute Disease, Aged, psychology, Aged, 80 and over, Confusion, epidemiology, Female, Geriatric Assessment, Hearing Disorders, complications, Homes for the Aged, Humans, Iowa, epidemiology, Long-Term Care, psychology, Longitudinal Studies, Male, Mass Screening, Nursing Homes, Prevalence, Risk Factors, Rural Population, Vision Disorders, complications |
Mortality and morbidity in nonagenarian patients following hip fracture surgery. | Formiga F, Lopez-Soto A, Sacanella E, Coscojuela A, Suso S, Pujol R | Gerontology | 2003 |
Aged, Aged, 80 and over, Female, Femoral Neck Fractures, mortality, Follow-Up Studies, Frail Elderly, Humans, Male, Pain, Postoperative, Prospective Studies, Walking, physiology |
The last forty-eight hours of life in a Portuguese palliative care unit: does it differ from elsewhere? | Gonçalves JF, Alvarenga M, Silva A | Journal of palliative medicine | 2003 |
Drug Utilization Review, Female, Humans, Male, Medical Audit, Neoplasms, nursing, Palliative Care, standards, Portugal, Prospective Studies, Terminal Care, standards |
Systemic infection, interleukin 1beta, and cognitive decline in Alzheimer's disease. | Holmes C, El-Okl M, Williams AL, Cunningham C, Wilcockson D, Perry VH | Journal of neurology, neurosurgery, and psychiatry | 2003 |
Aged, Aged, 80 and over, Alzheimer Disease, etiology, Central Nervous System Bacterial Infections, complications, Cognition Disorders, diagnosis, Female, Follow-Up Studies, Humans, Interleukin-1, blood, Male, Neuropsychological Tests |
Postoperative confusion in schizophrenic patients is affected by interleukin-6. | Kudoh A, Takase H, Takahira Y, Katagai H, Takazawa T | Journal of clinical anesthesia | 2003 |
Abdomen, surgery, Adult, Aged, Analgesia, Epidural, Anesthesia, Epidural, Anesthesia, General, Confusion, blood, Humans, Hydrocortisone, blood, Interleukin-6, blood, Middle Aged, Postoperative Complications, blood, Schizophrenia, blood |
Treating depression in Alzheimer disease: efficacy and safety of sertraline therapy, and the benefits of depression reduction: the DIADS. | Lyketsos CG, DelCampo L, Steinberg M, Miles Q, Steele CD, Munro C, Baker AS, Sheppard JM, Frangakis C, Brandt J, Rabins PV | Archives of general psychiatry | 2003 |
Activities of Daily Living, psychology, Aged, Alzheimer Disease, drug therapy, Ambulatory Care, Caregivers, psychology, Cognition Disorders, diagnosis, Comorbidity, Depressive Disorder, drug therapy, Drug Administration Schedule, Female, Geriatric Assessment, Humans, Male, Mental Disorders, diagnosis, Neuropsychological Tests, Placebos, Psychiatric Status Rating Scales, Serotonin Uptake Inhibitors, therapeutic use, Sertraline, therapeutic use, Single-Blind Method, Treatment Outcome |
Six-month neuropsychological outcome of medical intensive care unit patients. | Jackson JC, Hart RP, Gordon SM, Shintani A, Truman B, May L, Ely EW | Critical care medicine | 2003 |
APACHE, Cognition Disorders, diagnosis, Depression, diagnosis, Female, Humans, Intensive Care Units, Length of Stay, Male, Middle Aged, Neuropsychological Tests, Prospective Studies, Quality of Life, Respiration, Artificial, adverse effects |
Clinical practice guidelines for the sustained use of sedatives and analgesics in the critically ill adult. | Jacobi J, Fraser GL, Coursin DB, Riker RR, Fontaine D, Wittbrodt ET, Chalfin DB, Masica MF, Bjerke HS, Coplin WM, Crippen DW, Fuchs BD, Kelleher RM, Marik PE, Nasraway SA, Murray MJ, Peruzzi WT, Lumb PD, | Critical care medicine | 2002 |
Adult, Analgesia, standards, Analgesics, administration & dosage, Conscious Sedation, standards, Critical Care, standards, Delirium, Humans, Hypnotics and Sedatives, administration & dosage, Pain Measurement, standards, Sleep, drug effects |
Exposure to opioid analgesia in cognitively impaired and delirious elderly hip fracture patients. | Adunsky A, Levy R, Mizrahi E, Arad M | Archives of gerontology and geriatrics | 2002 | |
Meperidine analgesia and delirium in aged hip fracture patients. | Adunsky A, Levy R, Heim M, Mizrahi E, Arad M | Archives of gerontology and geriatrics | 2002 | |
Development and validation of a risk-adjustment index for older patients: the high-risk diagnoses for the elderly scale. | Desai MM, Bogardus ST, Williams CS, Vitagliano G, Inouye SK | Journal of the American Geriatrics Society | 2002 |
Aged, Female, Geriatrics, Health Status Indicators, Humans, Male, Prospective Studies, Risk Adjustment |
Evaluation of a guided protocol for quality improvement in identifying common geriatric problems. | Bogardus ST, Richardson E, Maciejewski PK, Gahbauer E, Inouye SK | Journal of the American Geriatrics Society | 2002 |
Aged, Case-Control Studies, Clinical Protocols, Cohort Studies, Connecticut, Female, Geriatric Assessment, Hospitals, University, Humans, Male, Mass Screening, methods, Outpatient Clinics, Hospital, standards, Primary Health Care, Quality Assurance, Health Care |
A review of physical restraint minimization in the acute and residential care settings. | Evans D, Wood J, Lambert L | Journal of advanced nursing | 2002 |
Accidental Falls, prevention & control, Acute Disease, Aged, Critical Care, methods, Education, Nursing, Continuing, Geriatric Nursing, methods, Health Services Research, Humans, Program Evaluation, Residential Facilities, organization & administration, Restraint, Physical, utilization |
Delirium superimposed on dementia: a systematic review. | Fick DM, Agostini JV, Inouye SK | Journal of the American Geriatrics Society | 2002 |
Delirium, complications, Dementia, complications, Hospitalization, Humans, Prevalence, Prognosis, Randomized Controlled Trials as Topic, Research, Risk Factors |
Iatrogenic causes of falls in hospitalised elderly patients: a case-control study. | Frels C, Williams P, Narayanan S, Gariballa SE | Postgraduate medical journal | 2002 |
Accidental Falls, prevention & control, Aged, Aged, 80 and over, Anti-Anxiety Agents, adverse effects, Benzodiazepines, Case-Control Studies, England, Female, Geriatric Assessment, Hospitalization, Humans, Logistic Models, Male, Odds Ratio, Risk Factors |
Designing adverse event prevention programs using quality management methods: the case of falls in hospital. | Grenier-Sennelier C, Lombard I, Jeny-Loeper C, Maillet-Gouret MC, Minvielle E | International journal for quality in health care : journal of the International Society for Quality in Health Care / ISQua | 2002 |
Accidental Falls, prevention & control, Aged, Female, France, Health Services Research, Humans, Male, Program Development, Rehabilitation Centers, organization & administration, Risk Management, methods, Total Quality Management, methods |
A novel approach to the prevention of postoperative delirium in the elderly after gastrointestinal surgery. | Aizawa K, Kanai T, Saikawa Y, Takabayashi T, Kawano Y, Miyazawa N, Yamamoto T | Surgery today | 2002 |
Aged, Aged, 80 and over, Analgesics, Opioid, administration & dosage, Anti-Anxiety Agents, administration & dosage, Delirium, etiology, Diazepam, administration & dosage, Digestive System Surgical Procedures, adverse effects, Drug Therapy, Combination, Female, Flunitrazepam, administration & dosage, Gastrointestinal Neoplasms, surgery, Humans, Infusions, Intravenous, Injections, Intramuscular, Male, Meperidine, administration & dosage, Postoperative Complications, prevention & control, Premedication, Prospective Studies |
An open trial of olanzapine for the treatment of delirium in hospitalized cancer patients. | Breitbart W, Tremblay A, Gibson C | Psychosomatics | 2002 |
Adult, Aged, Aged, 80 and over, Analysis of Variance, Antipsychotic Agents, therapeutic use, Benzodiazepines, Chi-Square Distribution, Delirium, drug therapy, Female, Humans, Inpatients, psychology, Logistic Models, Male, Middle Aged, Neoplasms, complications, Pirenzepine, analogs & derivatives, Prospective Studies, Risk Factors, Severity of Illness Index |
Delirium and psychotic symptoms--an integrative model. | Charlton BG, Kavanau JL | Medical hypotheses | 2002 |
Consciousness Disorders, Delirium, physiopathology, Electroconvulsive Therapy, Electroencephalography, Humans, Models, Psychological, Psychotic Disorders, physiopathology |
Systematic detection and multidisciplinary care of delirium in older medical inpatients: a randomized trial. | Cole MG, McCusker J, Bellavance F, Primeau FJ, Bailey RF, Bonnycastle MJ, Laplante J | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne | 2002 |
Aged, Aged, 80 and over, Delirium, nursing, Female, Geriatric Assessment, Humans, Male, Patient Care Planning, Patient Care Team, Proportional Hazards Models, Quebec |
Delirium after coronary bypass surgery evaluated by the organic brain syndrome protocol. | Eriksson M, Samuelsson E, Gustafson Y, Aberg T, Engström KG | Scandinavian cardiovascular journal : SCJ | 2002 |
Aged, Clinical Protocols, Coronary Artery Bypass, adverse effects, Coronary Disease, complications, Delirium, complications, Delirium, Dementia, Amnestic, Cognitive Disorders, complications, Female, Hallucinations, complications, Humans, Intensive Care, Length of Stay, Male, Postoperative Complications, diagnosis, Treatment Outcome |
Delirium in patients undergoing hematopoietic stem cell transplantation. | Fann JR, Roth-Roemer S, Burington BE, Katon WJ, Syrjala KL | Cancer | 2002 |
Adult, Delirium, epidemiology, Female, Hematopoietic Stem Cell Transplantation, adverse effects, Humans, Logistic Models, Male, Middle Aged, Prospective Studies, Risk Factors |
Delirium in acute stroke. | Ferro JM, Caeiro L, Verdelho A | Current opinion in neurology | 2002 |
Acute Disease, Delirium, epidemiology, Humans, Risk Factors, Stroke, epidemiology |
Delirium in patients on hemodialysis therapy. | Fukunishi I, Kitaoka T, Shirai T, Kino K, Kanematsu E, Sato Y | Nephron | 2002 |
Aged, Delirium, epidemiology, Humans, Kidney Failure, Chronic, epidemiology, Prevalence, Renal Dialysis, adverse effects |
Delirium in advanced cancer: a psychoeducational intervention for family caregivers. | Gagnon P, Charbonneau C, Allard P, Soulard C, Dumont S, Fillion L | Journal of palliative care | 2002 |
Adaptation, Psychological, Aged, Attitude of Health Personnel, Attitude to Health, Caregivers, education, Delirium, etiology, Family, psychology, Female, Focus Groups, Health Education, methods, Health Knowledge, Attitudes, Practice, Home Nursing, education, Humans, Male, Middle Aged, Neoplasms, complications, Pamphlets, Program Evaluation, Qualitative Research, Risk Factors, Teaching Materials, standards, Terminal Care, methods |
The prevalence and documentation of impaired mental status in elderly emergency department patients. | Hustey FM, Meldon SW | Annals of emergency medicine | 2002 |
Aged, Aged, 80 and over, Cognition Disorders, diagnosis, Delirium, diagnosis, Emergency Service, Hospital, Female, Geriatric Assessment, Hospitals, Teaching, Humans, Male, Mental Disorders, diagnosis, Mental Status Schedule, Prevalence, Prospective Studies, Risk Factors, Urban Population |
Deciphering the 4 D's: cognitive decline, delirium, depression and dementia--a review. | Insel KC, Badger TA | Journal of advanced nursing | 2002 |
Aged, Cognition Disorders, diagnosis, Delirium, diagnosis, Dementia, diagnosis, Depression, diagnosis, Humans, Task Performance and Analysis |
Dementia and delirium in 4 patients with Machado-Joseph disease. | Ishikawa A, Yamada M, Makino K, Aida I, Idezuka J, Ikeuchi T, Soma Y, Takahashi H, Tsuji S | Archives of neurology | 2002 |
Delirium, complications, Dementia, complications, Female, Humans, Machado-Joseph Disease, complications, Male, Middle Aged |
Delirium resulting from paraneoplastic limbic encephalitis caused by Hodgkin's disease. | Kung S, Mueller PS, Geda YE, Krahn LE | Psychosomatics | 2002 |
Delirium, etiology, Female, Hodgkin Disease, complications, Humans, Limbic Encephalitis, complications, Middle Aged, Psychiatric Status Rating Scales |
Anticipating and preventing delirium. | Lampley-Dallas VT | The Journal of the Oklahoma State Medical Association | 2002 |
Aged, Aged, 80 and over, Delirium, diagnosis, Female, Humans, Male |
Confusion assessment method in the diagnostics of delirium among aged hospital patients: would it serve better in screening than as a diagnostic instrument? | Laurila JV, Pitkala KH, Strandberg TE, Tilvis RS | International journal of geriatric psychiatry | 2002 |
Aged, Aged, 80 and over, Algorithms, Confusion, Cross-Sectional Studies, Delirium, diagnosis, Female, Hospitalization, Humans, Male, Psychiatric Status Rating Scales, standards, Sensitivity and Specificity |
Delirium and dehydration: some fluid for thought? | Lawlor PG | Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer | 2002 |
Analgesics, Opioid, adverse effects, Dehydration, complications, Delirium, chemically induced, Diagnostic Errors, Family, psychology, Fluid Therapy, Humans, Neoplasms, complications, Palliative Care, methods, Water-Electrolyte Balance, physiology |
Intractable delirium associated with ziconotide successfully treated with electroconvulsive therapy. | Levin T, Petrides G, Weiner J, Saravay S, Multz AS, Bailine S | Psychosomatics | 2002 |
Adult, Analgesics, adverse effects, Calcium Channel Blockers, adverse effects, Delirium, chemically induced, Electroconvulsive Therapy, Humans, Male, Peripheral Nervous System Diseases, drug therapy, omega-Conotoxins, administration & dosage |
Delirium predicts 12-month mortality. | McCusker J, Cole M, Abrahamowicz M, Primeau F, Belzile E | Archives of internal medicine | 2002 |
Aged, Confounding Factors (Epidemiology), Delirium, complications, Dementia, complications, Hospitalization, Humans, Mortality, Prognosis, Proportional Hazards Models, Prospective Studies, Severity of Illness Index, Survival Analysis |
Documentation of delirium in elderly patients with hip fracture. | Milisen K, Foreman MD, Wouters B, Driesen R, Godderis J, Abraham IL, Broos PL | Journal of gerontological nursing | 2002 |
Age Factors, Aged, Aged, 80 and over, Delirium, diagnosis, Documentation, standards, Female, Hip Fractures, classification, Humans, Male, Medical Records, statistics & numerical data, Nursing Records, standards, Postoperative Complications, diagnosis, Retrospective Studies |
Confusion/delirium following cataract surgery: an incidence study of 1-year duration. | Milstein A, Pollack A, Kleinman G, Barak Y | International psychogeriatrics / IPA | 2002 |
Adult, Age Factors, Aged, Aged, 80 and over, Cataract Extraction, Confusion, diagnosis, Delirium, diagnosis, Female, Humans, Incidence, Longitudinal Studies, Male, Middle Aged, Postoperative Complications, Severity of Illness Index |
Acute postoperative delirium: definitions, incidence, recognition, and interventions. | O'Brien D | Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses / American Society of PeriAnesthesia Nurses | 2002 |
Acute Disease, Delirium, epidemiology, Humans, Incidence, Nursing Assessment, Postanesthesia Nursing, methods |
Delirium: an important (but often unrecognized) clinical syndrome. | Rabinowitz T | Current psychiatry reports | 2002 |
Delirium, psychology, Humans, Risk Factors |
Delirium. Pragmatic guidance for managing a common, confounding, and sometimes lethal condition. | Samuels SC, Evers MM | Geriatrics | 2002 |
Aged, Anti-Anxiety Agents, therapeutic use, Antipsychotic Agents, therapeutic use, Delirium, drug therapy, Diagnosis, Differential, Geriatric Assessment, Humans |
Assessing for delirium. | Schofield I | Nursing older people | 2002 |
Age Factors, Aged, Delirium, diagnosis, Humans |
Agitated delirium and sudden death. | Vilke GM, Chan TC | Prehospital emergency care : official journal of the National Association of EMS Physicians and the National Association of State EMS Directors | 2002 |
Adult, Asphyxia, etiology, Death, Sudden, etiology, Delirium, complications, Emergency Medical Services, Female, Humans, Immobilization, adverse effects, Male, Middle Aged, Restraint, Physical, United States |
Confusion assessment method (CAM). | Waszynski CM | Insight (American Society of Ophthalmic Registered Nurses) | 2002 |
Delirium, diagnosis, Humans, Psychological Tests, Reproducibility of Results |
A case study of postoperative delirium. | Wendel I | AORN journal | 2002 |
Age Factors, Aged, Aged, 80 and over, Delirium, diagnosis, Dementia, complications, Geriatric Assessment, Humans, Male, Nursing Assessment, Operating Room Nursing, methods, Pain, Postoperative, complications, Postoperative Complications, diagnosis, Preoperative Care, Risk Factors |
Delirium severity and psychomotor types: their relationship with outcomes after hip fracture repair. | Marcantonio E, Ta T, Duthie E, Resnick NM | Journal of the American Geriatrics Society | 2002 |
Aged, Aged, 80 and over, Cohort Studies, Delirium, etiology, Female, Hip Fractures, complications, Humans, Length of Stay, Male, Nursing Homes, Outcome Assessment (Health Care), Prospective Studies, Psychomotor Disorders, complications, Recovery of Function, physiology, Severity of Illness Index |
Symptoms of delirium among elderly medical inpatients with or without dementia. | Cole MG, McCusker J, Dendukuri N, Han L | The Journal of neuropsychiatry and clinical neurosciences | 2002 |
Adult, Aged, Aged, 80 and over, Cluster Analysis, Delirium, diagnosis, Dementia, complications, Female, Hospitalization, Humans, Male, Middle Aged, Prevalence, Psychiatric Status Rating Scales, Psychomotor Disorders, epidemiology, Severity of Illness Index |
Cortisol response to surgery and postoperative confusion in depressed patients under general anesthesia with fentanyl. | Kudoh A, Takahira Y, Katagai H, Takazawa T | Neuropsychobiology | 2002 |
Adrenocorticotropic Hormone, blood, Adult, Anesthesia, General, adverse effects, Anesthetics, Intravenous, administration & dosage, Case-Control Studies, Confusion, blood, Depressive Disorder, blood, Fentanyl, administration & dosage, Humans, Hydrocortisone, blood, Middle Aged, Narcotics, adverse effects, Orthopedic Procedures, Postoperative Complications, blood, Propofol, adverse effects, Time Factors |
Schizophrenic patients who develop postoperative confusion have an increased norepinephrine and cortisol response to surgery. | Kudoh A, Takahira Y, Katagai H, Takazawa T | Neuropsychobiology | 2002 |
Adrenocorticotropic Hormone, blood, Adult, Aged, Case-Control Studies, Confusion, blood, Female, Humans, Hydrocortisone, blood, Male, Middle Aged, Norepinephrine, blood, Postoperative Complications, blood, Schizophrenia, blood, Time Factors |
Anesthesia with ketamine, propofol, and fentanyl decreases the frequency of postoperative psychosis emergence and confusion in schizophrenic patients. | Kudoh A, Katagai H, Takazawa T | Journal of clinical anesthesia | 2002 |
Adult, Aged, Anesthesia, General, Anesthesia, Intravenous, Anesthetics, Dissociative, adverse effects, Anesthetics, Intravenous, Confusion, chemically induced, Female, Fentanyl, Fractures, Bone, surgery, Humans, Ketamine, adverse effects, Male, Middle Aged, Postoperative Complications, psychology, Propofol, Prospective Studies, Psychoses, Substance-Induced, etiology, Schizophrenic Psychology |
Small-dose ketamine improves the postoperative state of depressed patients. | Kudoh A, Takahira Y, Katagai H, Takazawa T | Anesthesia and analgesia | 2002 |
Adult, Anesthesia, General, Anesthetics, Dissociative, Blood Loss, Surgical, Depressive Disorder, psychology, Female, Humans, Ketamine, Male, Middle Aged, Pain Measurement, Pain, Postoperative, psychology, Postoperative Period, Psychiatric Status Rating Scales |
Antidepressant treatment for chronic depressed patients should not be discontinued prior to anesthesia. | Kudoh A, Katagai H, Takazawa T | Canadian journal of anaesthesia = Journal canadien d'anesthésie | 2002 |
Adult, Anesthesia, Antidepressive Agents, adverse effects, Arrhythmias, Cardiac, epidemiology, Chronic Disease, Confusion, etiology, Depression, drug therapy, Hemodynamics, Humans, Hypotension, epidemiology, Intraoperative Complications, etiology, Middle Aged |
Preoperative factors associated with postoperative change in confusion assessment method score in hip fracture patients. | Zakriya KJ, Christmas C, Wenz JF, Franckowiak S, Anderson R, Sieber FE | Anesthesia and analgesia | 2002 |
Age Factors, Aged, Aged, 80 and over, Analysis of Variance, Confusion, diagnosis, Female, Hip Fractures, surgery, Humans, Leukocyte Count, Logistic Models, Male, Middle Aged, Neuropsychological Tests, Odds Ratio, Orthopedic Procedures, adverse effects, Postoperative Complications, epidemiology, Preoperative Care, Risk Factors, Sodium, blood |
Patients with hip fracture: subgroups and their outcomes. | Eastwood EA, Magaziner J, Wang J, Silberzweig SB, Hannan EL, Strauss E, Siu AL | Journal of the American Geriatrics Society | 2002 |
Activities of Daily Living, Aged, Aged, 80 and over, Cluster Analysis, Decision Trees, Female, Geriatric Assessment, Hip Fractures, physiopathology, Hospitalization, Humans, Male, New York City, Outcome Assessment (Health Care), Prospective Studies, Treatment Outcome |
Improving medication use in newly admitted home healthcare patients: a randomized controlled trial. | Meredith S, Feldman P, Frey D, Giammarco L, Hall K, Arnold K, Brown NJ, Ray WA | Journal of the American Geriatrics Society | 2002 |
Aged, Drug Therapy, standards, Follow-Up Studies, Home Care Agencies, Home Care Services, standards, Humans, Interviews as Topic, Outcome Assessment (Health Care) |
A scale for measuring patient perceptions of the quality of end-of-life care and satisfaction with treatment: the reliability and validity of QUEST. | Sulmasy DP, McIlvane JM, Pasley PM, Rahn M | Journal of pain and symptom management | 2002 |
Aged, Female, Humans, Male, Palliative Care, standards, Patient Satisfaction, Quality Assurance, Health Care, methods, Reproducibility of Results |
Patients' ratings of quality and satisfaction with care at the end of life. | Sulmasy DP, McIlvane JM | Archives of internal medicine | 2002 |
Academic Medical Centers, standards, Adult, Aged, Aged, 80 and over, Analysis of Variance, Cross-Sectional Studies, District of Columbia, Female, Hospice Care, psychology, Humans, Internship and Residency, standards, Male, Middle Aged, New York, Nurse-Patient Relations, Outcome Assessment (Health Care), Palliative Care, psychology, Patient Satisfaction, Physician-Patient Relations, Quality Assurance, Health Care, Quality of Life, Questionnaires, Resuscitation Orders |