Delirium Bibliography

Delirium Bibliography books graphicWhat is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!

How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.

Reference Information

Title
Effect of acute pain on the association between preoperative cognitive impairment and postoperative delirium: a secondary analysis of three trials
Authors
Ma, J. H. Liu, Y. F. Hong, H. Li, C. J. Cui, F. Mu, D. L. Wang, D. X.
Year
2022
Journal
Br J Anaesth
Abstract

BACKGROUND: The association between preoperative cognitive impairment, postoperative pain, and postoperative delirium in older patients after noncardiac surgery is not known. METHODS: This was a secondary analysis of datasets from three previous studies. Patients aged ≥55 yr who underwent elective noncardiac surgery were enrolled. Preoperative cognitive impairment was defined as Mini-Mental State Examination <27. Pain intensity with movement was assessed using an 11-point numeric rating scale at 12-h intervals during the first 72 h after surgery; time-weighted average (TWA) pain score was calculated. Primary outcome was the occurrence of delirium within the first 5 postoperative days. Mediation analysis was used to investigate the relationships between cognitive impairment, pain score, and delirium. RESULTS: A total of 1497 patients were included. Prevalence of preoperative cognitive impairment was 40.3% (603/1497). Patients with cognitive impairment suffered higher TWA pain score within 72 h (4 [3-5] vs 3 [2-5], P=0.004) and more delirium within 5 days (12.9% [78/603] vs 4.9% [44/894], P<0.001) when compared with those without. Total and direct associations between cognitive impairment and delirium were (adjusted β) 8.3% (95% confidence interval [CI], 4.8-12.0%; P<0.001) and 7.8% (95% CI, 4.4-12.0%; P<0.001), respectively. A significant indirect association with acute pain was observed between cognitive impairment and delirium (adjusted β=0.4%; 95% CI, 0.1-1.0%; P=0.006), accounting for 4.9% of the total effect. CONCLUSIONS: The association between preoperative cognitive impairment and delirium is significantly mediated by acute pain in patients after noncardiac surgery. Considering the small effect size, clinical significance of this mediation effect requires further investigation.

PMID

35933172

Keywords

cognitive dysfunction
delirium
mediation analysis
postoperative complications
postoperative pain

Page(s)
Issue

Search:
Total Records Found: 6347, showing 100 per page
TitleAuthorsJournalYearKeywords
Nomogram for Predicting Postoperative Delirium After Deep Brain Stimulation Surgery for Parkinson's Disease Wang, X. Q. Zhuang, H. X. Zhang, L. X. Chen, X. Niu, C. S. Zhao, M. World Neurosurg 2019

Deep brain stimulation
Nomograms
Parkinson’s disease
Postoperative delirium

Automated tracking of level of consciousness and delirium in critical illness using deep learning Sun, H. Kimchi, E. Akeju, O. Nagaraj, S. B. McClain, L. M. Zhou, D. W. Boyle, E. Zheng, W. L. Ge, W. Westover, M. B. NPJ Digital Medicine 2019

propofol
adult
aged
APACHE
article
artificial ventilation
body mass
brain function
clinical research
consciousness level
convolutional neural network
critical illness
deep learning
delirium
elective surgery
electroencephalography
eye movement
female
human
intensive care unit
long short term memory network
major clinical study
male
neuromonitoring
observational study
priority journal
prospective study
recurrent neural network
Richmond Agitation Sedation Scale
sedation
sensitivity and specificity

Impact of natural light exposure on delirium burden in adult patients receiving invasive mechanical ventilation in the ICU: a prospective study Smonig, R. Magalhaes, E. Bouadma, L. Andremont, O. de Montmollin, E. Essardy, F. Mourvillier, B. Lebut, J. Dupuis, C. Neuville, M. Lermuzeaux, M. Timsit, J. F. Sonneville, R. Ann Intensive Care 2019

Agitation
Antipsychotics
Delirium
Hallucinations
Light

Differences in 90-day mortality of delirium subtypes in the intensive care unit: A retrospective cohort study Rood, P. J. T. van de Schoor, F. van Tertholen, K. Pickkers, P. van den Boogaard, M. J Crit Care 2019

Critical care
Delirium
Icu
Mortality
Subtypes

The Role of Delirium and Other Risk Factors on Mortality in Elderly Patients with Critical Limb Ischemia Undergoing Major Lower Limb Amputation Roijers, J. P. Hopmans, C. J. Janssen, T. L. Mulder, P. G. H. Buimer, M. G. Ho, G. H. de Groot, H. G. W. Veen, E. J. van der Laan, L. Ann Vasc Surg 2019
Antipsychotics for preventing delirium in hospitalized adults a systematic review Oh, E. S. Needham, D. M. Nikooie, R. Wilson, L. M. Zhang, A. Robinson, K. A. Neufeld, K. J. Annals of Internal Medicine 2019

neuroleptic agent
adult
adverse event
cognition
delirium
delirium rating scale revised 98
Diagnostic and Statistical Manual of Mental Disorders
disease duration
drug safety
extrapyramidal symptom
heart arrhythmia
hospital patient
human
incidence
length of stay
mental disease assessment
meta analysis
mortality
neuroleptic malignant syndrome
priority journal
prophylaxis
review
sedation
systematic review

Antipsychotics for treating delirium in hospitalized adults a systematic review Nikooie, R. Neufeld, K. J. Oh, E. S. Wilson, L. M. Zhang, A. Robinson, K. A. Needham, D. M. Annals of Internal Medicine 2019

amisulpride
aripiprazole
haloperidol
neuroleptic agent
olanzapine
placebo
quetiapine
risperidone
ziprasidone
adult
Clinical Global Impression scale
critical illness
critically ill patient
delirium
drug withdrawal
extrapyramidal symptom
heart disease
hospital mortality
hospital patient
human
length of stay
meta analysis
neurologic disease
palliative therapy
priority journal
psychopharmacotherapy
QTc interval
randomized controlled trial (topic)
review
sedation
systematic review

Exploiting Machine Learning Algorithms and Methods for the Prediction of Agitated Delirium After Cardiac Surgery: Models Development and Validation Study Mufti, H. N. Hirsch, G. M. Abidi, S. R. Abidi, S. S. R. JMIR Med Inform 2019

cardiac surgery
delirium
machine learning
predictive modeling

Predictors and prognosis of delirium among older subjects in cardiac intensive care unit: focus on potentially preventable forms Mossello, E. Baroncini, C. Pecorella, L. Giulietti, C. Chiti, M. Caldi, F. Cavallini, M. C. Simoni, D. Baldasseroni, S. Fumagalli, S. Valoti, P. Stroppa, S. Parenti, K. Ungar, A. Masotti, G. Marchionni, N. Di Bari, M. Eur Heart J Acute Cardiovasc Care 2019

*Delirium
*acute coronary syndrome
*aged
*intensive care unit

Dysfunction of the blood-brain barrier in postoperative delirium patients, referring to the axonal damage biomarker phosphorylated neurofilament heavy subunit Mietani, K. Sumitani, M. Ogata, T. Shimojo, N. Inoue, R. Abe, H. Kawamura, G. Yamada, Y. PLoS One 2019
The 4 ‘a’s test for detecting delirium in acute medical patients: A diagnostic accuracy study Maclullich, A. M. J. Shenkin, S. D. Goodacre, S. Godfrey, M. Hanley, J. Stíobhairt, A. Lavender, E. Boyd, J. Stephen, J. Weir, C. Macraild, A. Steven, J. Black, P. Diernberger, K. Hall, P. Tieges, Z. Fox, C. Anand, A. Young, J. Siddiqi, N. Gray, A. Health Technology Assessment 2019

ISRCTN53388093
age
Arousal Attention Abbreviated Mental Test 4
article
awareness
biomedical technology assessment
clinical practice
community care
confidence interval
cost benefit analysis
cost effectiveness analysis
delirium
diagnostic accuracy
diagnostic test accuracy study
diagnostic value
documentation
emergency ward
England
false negative result
false positive result
frailty
health care policy
health economics
health status
hospital cost
hospitalization
human
information processing
interview
length of stay
long term care
medical education
mortality rate
national health organization
national health service
practice guideline
probability
psychologic assessment
qualitative research
receiver operating characteristic
scoring system
sensitivity and specificity
statistics
surgery
systematic review
United Kingdom
ward

Initiation and continuation of antipsychotic medicines in older people following non-psychiatric hospital admission Kalisch Ellett, L. M. Pratt, N. L. Apajee, J. Roughead, E. E. Int J Clin Pharm 2019

Antipsychotic
Australia
Delirium
Dementia
Elderly
Hospital admission

Staged Implementation of Awakening and Breathing, Coordination, Delirium Monitoring and Management, and Early Mobilization Bundle Improves Patient Outcomes and Reduces Hospital Costs Hsieh, S. J. Otusanya, O. Gershengorn, H. B. Hope, A. A. Dayton, C. Levi, D. Garcia, M. Prince, D. Mills, M. Fein, D. Colman, S. Gong, M. N. Critical Care Medicine 2019

adult
arousal
article
artificial ventilation
clinical practice
cohort analysis
controlled study
decubitus
delirium
female
hospital cost
human
length of stay
major clinical study
male
medical intensive care unit
mobilization
prospective study
ventilated patient

The Prevalence of Delirium in An Older Acute Surgical Population and Its Effect on Outcome Hewitt, J. Owen, S. Carter, B. R. Stechman, M. J. Tay, H. S. Greig, M. McCormack, C. Pearce, L. McCarthy, K. Myint, P. K. Moug, S. J. Geriatrics 2019

Cognitive impairment
delirium
older surgical patients

Care challenges in older general hospital patients : Impact of cognitive impairment and other patient-related factors Hendlmeier, I. Bickel, H. Hessler-Kaufmann, J. B. Schaufele, M. Z Gerontol Geriatr 2019

Adverse events
Cognitive impairment
Cross-sectional studies
Dementia
Nursing

Efficacy of music on sedation, analgesia and delirium in critically ill patients. A systematic review of randomized controlled trials Garcia Guerra, G. Almeida, L. Zorzela, L. King-Jones, S. Joffe, A. R. Hartling, L. Jou, H. Vohra, S. J Crit Care 2019

Analgesia
Delirium
Music
Sedation
Systematic review

Postoperative Pressure Ulcers After Geriatric Hip Fracture Surgery Are Predicted by Defined Preoperative Comorbidities and Postoperative Complications Galivanche, A. R. Kebaish, K. J. Adrados, M. Ottesen, T. D. Varthi, A. G. Rubin, L. E. Grauer, J. N. The Journal of the American Academy of Orthopaedic Surgeons 2019

adult
article
cohort analysis
comorbidity
complication
decubitus
female
hip fracture
human
insulin dependent diabetes mellitus
major clinical study
male
multicenter study
platelet count
pneumonia
postoperative delirium
preoperative evaluation
risk factor
sepsis
surgeon
surgery
total quality management
urinary tract infection

The Healthy Heart-Mind Trial: Randomized Controlled Trial of Melatonin for Prevention of Delirium Ford, A. H. Flicker, L. Kelly, R. Patel, H. Passage, J. Wibrow, B. Anstey, M. Edwards, M. Almeida, O. P. J Am Geriatr Soc 2019

cardiothoracic
delirium
melatonin
prevention
surgery

The Caregiver Burden of Delirium in Older Adults With Alzheimer Disease and Related Disorders Fong, T. G. Racine, A. M. Fick, D. M. Tabloski, P. Gou, Y. Schmitt, E. M. Hshieh, T. T. Metzger, E. Bertrand, S. E. Marcantonio, E. R. Jones, R. N. Inouye, S. K. J Am Geriatr Soc 2019

Alzheimer disease
Alzheimer disease or related disorder
caregiver burden
delirium burden
dementia
patient burden

Geriatric Events Among Older Adults Undergoing Nonelective Surgery Are Associated with Poor Outcomes Dworsky, J. Q. Childers, C. P. Copeland, T. Maggard-Gibbons, M. Tan, H. J. Saliba, D. Russell, M. M. Am Surg 2019
Shifting the focus: A QI project to improve the management of delirium in patients with hip fracture Dormandy, L. Mufti, S. Higgins, E. Bailey, C. Dixon, M. Future Healthc J 2019

Neck of femur fracture
delirium
perioperative medicine

Impact of a delirium prevention project among older hospitalized patients who underwent orthopedic surgery: a retrospective cohort study Choi, J. Y. Kim, K. I. Kang, M. G. Lee, Y. K. Koo, K. H. Oh, J. H. Park, Y. H. Suh, J. Kim, N. H. Yoo, H. J. Koo, J. Moon, H. M. Kim, E. H. Park, K. Kim, C. H. BMC Geriatr 2019

Delirium
Multidisciplinary geriatric intervention
Quality improvement project

Melatonin for the prevention of postoperative delirium in older adults: a systematic review and meta-analysis Campbell, A. M. Axon, D. R. Martin, J. R. Slack, M. K. Mollon, L. Lee, J. K. BMC Geriatr 2019

Delirium
Geriatric
Melatonin
Postoperative
Ramelteon

Assessment of a Geriatric Hip Fracture Program: Analysis of Harmful Adverse Events Using the Global Trigger Tool Blood, T. D. Deren, M. E. Goodman, A. D. Hayda, R. A. Trafton, P. G. Journal of Bone and Joint Surgery - American Volume 2019

acute blood loss anemia
age
aged
anemia
article
Charlson Comorbidity Index
clinical effectiveness
controlled study
death
disease severity
female
femoral neck fracture
femur intertrochanteric fracture
frequency
geriatric care
Geriatric Hip Fracture Program
Global Trigger Tool
health program
hip fracture
hospital admission
hospital patient
hospital readmission
human
length of stay
major clinical study
male
musculoskeletal disease assessment
postoperative delirium
predictor variable
priority journal
risk factor
trend study
urinary tract infection
very elderly

Clinical management of delirium: The response depends on the subtypes. An observational cohort study in 602 patients Zipser, C. M. Knoepfel, S. Hayoz, P. Schubert, M. Ernst, J. von Kanel, R. Boettger, S. Palliat Support Care 2019

Antipsychotics
Delirium
Hyperactive
Hypoactive
Management of delirium
Psychotropics
Subtypes

Predisposing and precipitating factors for delirium in neurology: a prospective cohort study of 1487 patients Zipser, C. M. Deuel, J. Ernst, J. Schubert, M. Weller, M. von Kanel, R. Boettger, S. J Neurol 2019

Delirium
Neurology
Neuropsychiatry
Risk factor

Risk factors for postoperative delirium after spinal surgery: a systematic review and meta-analysis Zhu, C. Wang, B. Yin, J. Xue, Q. Gao, S. Xing, L. Wang, H. Liu, W. Liu, X. Aging Clin Exp Res 2019

Delirium
Postoperative
Risk factors
Spinal surgery

Dexmedetomidine for the prevention of postoperative delirium in elderly patients undergoing noncardiac surgery: A meta-analysis of randomized controlled trials Zeng, H. Li, Z. He, J. Fu, W. PLoS One 2019
Risk factors for delirium: Are therapeutic interventions part of it? Xing, J. Yuan, Z. Jie, Y. Liu, Y. Wang, M. Sun, Y. Neuropsychiatric Disease and Treatment 2019

arterial line
stomach tube
sedative agent
vasoactive agent
adult
aged
APACHE
article
artificial ventilation
bladder catheterization
catheter removal
clinical evaluation
clinical feature
clinical study
cohort analysis
controlled study
critically ill patient
delirium
disease association
early intervention
female
human
intensive care
intensive care unit
length of stay
major clinical study
male
observational study
prospective study
risk assessment
risk factor
treatment duration
tube removal
vein catheterization

Intraoperative hyperglycemia increases the incidence of postoperative delirium Windmann, V. Spies, C. Knaak, C. Wollersheim, T. Piper, S. K. Vorderwulbecke, G. Kurpanik, M. Kuenz, S. Lachmann, G. Minerva Anestesiol 2019
External Validation of Two Models to Predict Delirium in Critically Ill Adults Using Either the Confusion Assessment Method-ICU or the Intensive Care Delirium Screening Checklist for Delirium Assessment Wassenaar, A. Schoonhoven, L. Devlin, J. W. van Haren, F. M. P. Slooter, A. J. C. Jorens, P. G. van der Jagt, M. Simons, K. S. Egerod, I. Burry, L. D. Beishuizen, A. Matos, J. Donders, A. R. T. Pickkers, P. van den Boogaard, M. Crit Care Med 2019

adult
animal experiment
animal model
article
checklist
cohort analysis
controlled study
critically ill patient
female
intensive care psychosis
intensive care unit
male
nonhuman
prediction
prospective study
receiver operating characteristic
validation process

Risk Factors and Incidence of Postoperative Delirium in Patients Undergoing Laryngectomy Wang, Y. Yu, H. Qiao, H. Li, C. Chen, K. Shen, X. Otolaryngol Head Neck Surg 2019

head and neck cancer
laryngeal cancer
outcome
postoperative delirium

Regional cerebral oxygen saturation and postoperative delirium in endovascular surgery: a prospective cohort study Wang, X. Feng, K. Liu, H. Liu, Y. Ye, M. Zhao, G. Wang, T. Trials 2019

Delirium
Regional cerebral oxygen saturation
rSO2

The impact of analgosedation on mortality and delirium in critically ill patients: A systematic review and meta-analysis Wang, C. T. Mao, Y. Zhao, L. Ma, B. Intensive Crit Care Nurs 2019

Analgesia-based sedation
Analgesia-first sedation
Analogsedation
Critically ill patients
Delirium
Meta-analysis
Mortality
No sedation
Systematic review

Incidence and risk factors of postoperative delirium in patients admitted to the ICU after elective intracranial surgery: A prospective cohort study Wang, C. M. Huang, H. W. Wang, Y. M. He, X. Sun, X. M. Zhou, Y. M. Zhang, G. B. Gu, H. Q. Zhou, J. X. Eur J Anaesthesiol 2019
Association between preoperative nutritional status and postoperative delirium in individuals with coronary artery bypass graft surgery: A prospective cohort study Velayati, A. Vahdat Shariatpanahi, M. Shahbazi, E. Vahdat Shariatpanahi, Z. Nutrition 2019

adductor pollicis muscle
adult
arm circumference
article
body mass
cohort analysis
confusion assessment
controlled study
coronary artery bypass graft
coronary artery bypass surgery
disease association
disease severity
female
general health status assessment
high risk population
human
intensive care unit
major clinical study
male
malnutrition
mental disease assessment
muscle thickness
nutritional assessment
Nutritional Risk Screening 2002
nutritional status
observational study
postoperative delirium
preoperative period
prevalence
priority journal
prospective study
risk reduction
skeletal muscle
skinfold thickness
subjective global assessment
triceps brachii muscle

Prevalence and risk factors for delirium in elderly patients with severe burns: a retrospective cohort study van Yperen, D. T. Raats, J. W. Dokter, J. Ziere, G. Roukema, G. R. van Baar, M. E. van der Vlies, C. H. J Burn Care Res 2019

Elderly
burns
delirium
prevalence
risk factors

Delirium After Transcatheter Aortic Valve Implantation Under General Anesthesia: Incidence, Predictors, and Relation to Long-Term Survival van der Wulp, K. van Wely, M. van Heijningen, L. van Bakel, B. Schoon, Y. Verkroost, M. Gehlmann, H. Van Garsse, L. Vart, P. Kievit, P. Rikkert, M. O. Morshuis, W. van Royen, N. J Am Geriatr Soc 2019

general anesthesia
postoperative delirium
survival
transcatheter aortic valve implantation

Impact of a Premorbid Psychiatric Disorder on the Incidence of Delirium during ICU Stay, Morbidity, and Long-Term Mortality van der Kuur, A. Bethlehem, C. Bruins, N. de Jager, C. van Alst, C. Haagsma, O. G. Keijzers, A. Boerma, E. C. Crit Care Res Pract 2019
Identifying determinants for the application of physical or chemical restraint in the management of psychomotor agitation on the critical care unit Teece, A. Baker, J. Smith, H. J Clin Nurs 2019

agitation
critical care
decision-making
delirium
intensive care
nursing
restraint

Impact of a nurse engagement intervention on pain, agitation and delirium assessment in a community intensive care unit Tan, C. M. Camargo, M. Miller, F. Ross, K. Maximous, R. Yung, P. Marshall, C. Fleming, D. Law, M. Tsang, J. L. BMJ Open Qual 2019

critical care
healthcare quality improvement
nurses
performance measures
quality improvement

Predictors of delirium after cardiac surgery in patients with sleep disordered breathing Tafelmeier, M. Knapp, M. Lebek, S. Floerchinger, B. Camboni, D. Creutzenberg, M. Wittmann, S. Zeman, F. Schmid, C. Maier, L. S. Wagner, S. Arzt, M. Eur Respir J 2019
The relationship between obstructive sleep apnoea and postoperative delirium and pain: an observational study of a surgical cohort Strutz, P. K. Kronzer, V. Tzeng, W. Arrington, B. McKinnon, S. L. Ben Abdallah, A. Haroutounian, S. Avidan, M. S. Anaesthesia 2019

delirium
pain, postoperative
sleep apnoea, obstructive

Ultra-brief Screeners for Detecting Delirium Superimposed on Dementia Steensma, E. Zhou, W. Ngo, L. Gallagher, J. Inouye, S. Leslie, D. Boltz, M. Kolanowski, A. Mion, L. Marcantonio, E. R. Fick, D. J Am Med Dir Assoc 2019

Delirium
dementia
screening tools

Etiology and Related Factors of Postoperative Delirium in Orthopedic Surgery Song, K. J. Ko, J. H. Kwon, T. Y. Choi, B. W. Clin Orthop Surg 2019

Delirium
Etiology
Orthopedic surgery
Risk factor
was reported.

Preoperative transcranial Doppler and cerebral oximetry as predictors of delirium following valvular heart surgery: a case-control study Soh, S. Shim, J. K. Song, J. W. Choi, N. Kwak, Y. L. J Clin Monit Comput 2019

Cardiac surgical procedures
Delirium
Heart valve diseases
Spectroscopy, Near-infrared
Ultrasonography, Doppler, Transcranial

Identification of Patients With High Mortality Risk and Prediction of Outcomes in Delirium by Bispectral EEG Shinozaki, G. Bormann, N. L. Chan, A. C. Zarei, K. Sparr, N. A. Klisares, M. J. Jellison, S. S. Heinzman, J. T. Dahlstrom, E. B. Duncan, G. N. Gaul, L. N. Wanzek, R. J. Cramer, E. M. Wimmel, C. G. Sabbagh, S. Yuki, K. Weckmann, M. T. Yamada, T. Karam, M. J Clin Psychiatry 2019
Postoperative Delirium Is Associated with Long-term Decline in Activities of Daily Living Shi, Z. Mei, X. Li, C. Chen, Y. Zheng, H. Wu, Y. Zheng, H. Liu, L. Marcantonio, E. R. Xie, Z. Shen, Y. Anesthesiology 2019
Managing Delirium and Agitation in the Older Emergency Department Patient: The ADEPT Tool Shenvi, C. Kennedy, M. Austin, C. A. Wilson, M. P. Gerardi, M. Schneider, S. Ann Emerg Med 2019
Delirium detection in older acute medical inpatients: a multicentre prospective comparative diagnostic test accuracy study of the 4AT and the confusion assessment method Shenkin, S. D. Fox, C. Godfrey, M. Siddiqi, N. Goodacre, S. Young, J. Anand, A. Gray, A. Hanley, J. MacRaild, A. Steven, J. Black, P. L. Tieges, Z. Boyd, J. Stephen, J. Weir, C. J. MacLullich, A. M. J. BMC Med 2019

*4at
*Confusion assessment method (CAM)
*Delirium
*Diagnostic test accuracy
*Hospital
*Sensitivity
*Specificity

Occurrence Rate of Delirium in Acute Stroke Settings: Systematic Review and Meta-Analysis Shaw, R. C. Walker, G. Elliott, E. Quinn, T. J. Stroke 2019

delirium
humans
risk
stroke
systematic review

Delirium in an Acute Stroke Setting, Occurrence, and Risk Factors Shaw, R. Drozdowska, B. Taylor-Rowan, M. Elliott, E. Cuthbertson, G. Stott, D. J. Quinn, T. J. Stroke 2019

cognitive dysfunction
delirium
humans
odds ratio
stroke

The relationship between serum cobalamin, folic acid, and homocysteine and the risk of post-cardiac surgery delirium Shariatpanahi, M. V. Velayati, A. Jamalian, S. A. Babevaynejad, M. Shariatpanahi, Z. V. Neuropsychiatric Disease and Treatment 2019

cobalamin
folic acid
homocysteine
adult
aged
amino acid blood level
article
cardiopulmonary bypass
cohort analysis
controlled study
coronary artery bypass graft
enzyme immunoassay
female
folic acid blood level
hospital admission
human
intensive care unit
major clinical study
male
pathophysiology
population research
postoperative delirium
postoperative period
prospective study
surgical risk
vitamin blood level

The effect of volunteers' care and support on the health outcomes of older adults in acute care: A systematic scoping review Saunders, R. Seaman, K. Graham, R. Christiansen, A. J Clin Nurs 2019

Volunteers
clinical outcomes
confusion
frailty
hospital
nursing
older adults

Mitochondrial DNA Haplogroups and Delirium During Sepsis Samuels, D. C. Hulgan, T. Fessel, J. P. Billings, F. T. th Thompson, J. L. Chandrasekhar, R. Girard, T. D. Crit Care Med 2019
Effect of Flexible Family Visitation on Delirium Among Patients in the Intensive Care Unit: The ICU Visits Randomized Clinical Trial Rosa, R. G. Falavigna, M. da Silva, D. B. Sganzerla, D. Santos, M. M. S. Kochhann, R. de Moura, R. M. Eugenio, C. S. Haack, Tdsr Barbosa, M. G. Robinson, C. C. Schneider, D. de Oliveira, D. M. Jeffman, R. W. Cavalcanti, A. B. Machado, F. R. Azevedo, L. C. JAMA 2019

Anxiety
Brazil
Burnout, Professional
Critical Care/psychology
Cross-Over Studies
Delirium/*prevention & control
Depression
Family/*psychology
Female
Health Education
Hospitalization
Humans
Incidence
Intensive Care Units/*organization & administration
Male
Middle Aged
Time Factors
*Visitors to Patients

Deconstructing Poststroke Delirium in a Prospective Cohort of Patients With Intracerebral Hemorrhage Reznik, M. E. Drake, J. Margolis, S. A. Moody, S. Murray, K. Costa, S. Mahta, A. Wendell, L. C. Thompson, B. B. Rao, S. S. Barrett, A. M. Boukrina, O. Daiello, L. A. Asaad, W. F. Furie, K. L. Jones, R. N. Crit Care Med 2019
Impact of intraoperative blood pressure, blood pressure fluctuation, and pulse pressure on postoperative delirium in elderly patients with hip fracture: A prospective cohort study Radinovic, K. Markovic Denic, L. Milan, Z. Cirkovic, A. Baralic, M. Bumbasirevic, V. Injury 2019

Blood pressure
Clinical outcomes
Hip fracture
Postoperative delirium
Pulse pressure

Economic impact of delirium in Australia: a cost of illness study Pezzullo, L. Streatfeild, J. Hickson, J. Teodorczuk, A. Agar, M. R. Caplan, G. A. BMJ Open 2019

delirium & cognitive disorders
dementia
health economics

Delirium Predisposing and Triggering Factors in Nursing Home Residents: A Cohort Trial-Nested Case-Control Study Pérez-Ros, P. Martínez-Arnau, F. M. Baixauli-Alacreu, S. Caballero-Pérez, M. García-Gollarte, J. F. Tarazona-Santabalbina, F. Journal of Alzheimer's Disease 2019

urinary catheter
antidepressant agent
anxiolytic agent
cholinergic receptor blocking agent
neuroleptic agent
aged
anemia
article
autoimmune disease
Barthel index
case control study
cerebrovascular accident
cognitive defect
cohort analysis
controlled study
daily life activity
delirium
dementia
dependent personality disorder
depression
diabetes mellitus
disease predisposition
dysphagia
epilepsy
female
follow up
geriatric assessment
Geriatric Depression Scale
glomerulus filtration rate
hearing impairment
hospital admission
human
hypoglycemia
kidney failure
major clinical study
male
Mini Mental State Examination
nursing home patient
pain
Parkinson disease
pneumonia
predictive value
priority journal
urinary tract infection
urine incontinence
very elderly
visual impairment

Preoperative C-Reactive Protein/Albumin Ratio, a Risk Factor for Postoperative Delirium in Elderly Patients After Total Joint Arthroplasty Peng, J. Wu, G. Chen, J. Chen, H. Journal of Arthroplasty 2019

aged
area under the curve
arthroplasty
article
brain dysfunction
controlled study
diagnosis
diagnostic test accuracy study
epidural anesthesia
female
human
incidence
laboratory test
major clinical study
male
multivariate logistic regression analysis
postoperative delirium
preoperative evaluation
receiver operating characteristic
risk factor
sensitivity and specificity
albumin
biological marker
C reactive protein
endogenous compound

Combination of lithium and electroconvulsive therapy (ECT) is associated with higher odds of delirium and cognitive problems in a large national sample across the United States Patel, R. S. Bachu, A. Youssef, N. A. Brain Stimul 2019

Bipolar disorder
Cognitive side effects
Delirium
Depression
Electroconvulsive therapy
Lithium
Major depressive disorder
Treatment-resistant depression

The long-term prognosis of patients with delirium in the acute phase of stroke: PRospective Observational POLIsh Study (PROPOLIS) Pasinska, P. Wilk, A. Kowalska, K. Szyper-Maciejowska, A. Klimkowicz-Mrowiec, A. J Neurol 2019

Delirium
Long-term prognosis
Mortality
Stroke

Postoperative Delirium is Associated with Negative Outcomes and Long-Term Mortality in Elderly Koreans: A Retrospective Observational Study Park, E. A. Kim, M. Y. Medicina (Kaunas) 2019

delirium
elderly
mortality
outcome
surgery

Development of a Tool for the Assessment of Nurses' Attitudes Toward Delirium Papastavrou, E. Papaioannou, M. Evripidou, M. Tsangari, H. Kouta, C. Merkouris, A. J Nurs Meas 2019

attitude
delirium
nursing
validation

The risk factors associated with delirium after lumbar spine surgery in elderly patients Pan, Z. Huang, K. Huang, W. Kim, K. H. Wu, H. Yu, Y. Kim, K. N. Yi, S. Shin, D. A. Vora, D. Gragnaniello, C. Phan, K. Tasiou, A. Winder, M. J. Koga, H. Azimi, P. Kang, S. Y. Ha, Y. Quantitative Imaging in Medicine and Surgery 2019

angiotensin receptor antagonist
antihistaminic agent
benzodiazepine derivative
C reactive protein
cholinergic receptor blocking agent
dopamine receptor stimulating agent
hydroxymethylglutaryl coenzyme A reductase inhibitor
hypnotic agent
opiate
psychotropic agent
aged
article
brain hemorrhage
brain infarction
cerebrovascular accident
controlled study
dementia
diffusion weighted imaging
female
human
incidence
laminectomy
lumbar spine
magnetic resonance angiography
major clinical study
male
mild cognitive impairment
Mini Mental State Examination
operation duration
operative blood loss
parkinsonism
postoperative delirium
preoperative period
prospective study
risk factor
sex difference
spinal cord decompression
spine fusion
spine surgery
susceptibility weighted imaging
transient ischemic attack
very elderly

Incidence, risk factors, and cumulative risk of delirium among ICU patients: A case-control study Pan, Y. Yan, J. Jiang, Z. Luo, J. Zhang, J. Yang, K. International Journal of Nursing Sciences 2019

analgesic agent
sedative agent
aged
APACHE
article
artificial ventilation
case control study
controlled study
delirium
diagnostic accuracy
diagnostic test accuracy study
female
hospitalization
human
incidence
intensive care unit
length of stay
major clinical study
male
mental disease assessment
receiver operating characteristic
retrospective study
Richmond Agitation Sedation Scale
risk assessment
risk factor
sensitivity and specificity
very elderly

Perioperative dexmedetomidine reduces delirium in elderly patients after non-cardiac surgery: a systematic review and meta-analysis of randomized-controlled trials Pan, H. Liu, C. Ma, X. Xu, Y. Zhang, M. Wang, Y. Can J Anaesth 2019
International analgesia, sedation, and delirium practices: A prospective cohort study Owen, G. D. Stollings, J. L. Rakhit, S. Wang, L. Yu, C. Hosay, M. A. Stewart, J. W. Frutos-Vivar, F. Peñuelas, O. Esteban, A. Anzueto, A. R. Raymondos, K. Rios, F. Thille, A. W. González, M. Du, B. Maggiore, S. M. Matamis, D. Abroug, F. Amin, P. Zeggwag Journal of Intensive Care 2019

NCT02731898
benzodiazepine
dexmedetomidine
propofol
acute respiratory failure
adult
aged
analgesia
article
artificial ventilation
asthma
body mass
Canada
chronic lung disease
chronic obstructive lung disease
cohort analysis
coma
delayed emergence from anesthesia
delirium
female
human
major clinical study
male
multicenter study
neuromuscular disease
outcome assessment
priority journal
prospective study
retrospective study
Richmond Agitation Sedation Scale
sedation
Simplified Acute Physiology Score
United States

Validation of 3-minute diagnostic interview for CAM-defined Delirium to detect postoperative delirium in the recovery room: A prospective diagnostic study Olbert, M. Eckert, S. Morgeli, R. Kruppa, J. Spies, C. D. Eur J Anaesthesiol 2019
Antipsychotics for Preventing Delirium in Hospitalized Adults: A Systematic Review Oh, E. S. Needham, D. M. Nikooie, R. Wilson, L. M. Zhang, A. Robinson, K. A. Neufeld, K. J. Ann Intern Med 2019
Prevention of Early Postoperative Decline: A Randomized, Controlled Feasibility Trial of Perioperative Cognitive Training O'Gara, B. P. Mueller, A. Gasangwa, D. V. I. Patxot, M. Shaefi, S. Khabbaz, K. Banner-Goodspeed, V. Pascal-Leone, A. Marcantonio, E. R. Subramaniam, B. Anesth Analg 2019
Antipsychotics for Treating Delirium in Hospitalized Adults: A Systematic Review Nikooie, R. Neufeld, K. J. Oh, E. S. Wilson, L. M. Zhang, A. Robinson, K. A. Needham, D. M. Ann Intern Med 2019
Characteristics of Hospitalized Patients Screening Positive for Delirium Nguyen, T. H. Atayee, R. S. Derry, K. L. Hirst, J. Biondo, A. Edmonds, K. P. Am J Hosp Palliative Care 2019

Cam-icu
Doss
delirium
drugs
mortality
palliative

The effect of melatonin on delirium in hospitalised patients: A systematic review and meta-analyses with trial sequential analysis Ng, K. T. Teoh, W. Y. Khor, A. J. J Clin Anesth 2019

Agitation
Delirium
Length of hospital stay
Melatonin
Ramelteon

Predicting medication-associated altered mental status in hospitalized patients: Development and validation of a risk model Muñoz, M. A. Jeon, N. Staley, B. Henriksen, C. Xu, D. Weberpals, J. Winterstein, A. G. American Journal of Health-System Pharmacy 2019

adult
alcohol withdrawal syndrome
animal experiment
animal model
article
bootstrapping
cohort analysis
controlled study
delirium
drug information
electronic health record
female
high risk patient
hospital patient
hospitalization
hypernatremia
intensive care unit
male
mental health
multicenter study
nonhuman
pharmacist
prediction
psychosis
retrospective study
risk assessment
risk factor
validation process
atypical antipsychotic agent
haloperidol

Exploiting Machine Learning Algorithms and Methods for the Prediction of Agitated Delirium after Cardiac Surgery Mufti, H. N. Hirsch, G. M. Abidi, S. R. Abidi, S. S. R. JMIR Med Inform 2019
Risk factors for postoperative delirium in patients undergoing lower extremity joint arthroplasty: a retrospective population-based cohort study Memtsoudis, S. Cozowicz, C. Zubizarreta, N. Weinstein, S. M. Liu, J. Kim, D. H. Poultsides, L. Berger, M. M. Mazumdar, M. Poeran, J. Reg Anesth Pain Med 2019

adverse effects
complications
opioids
regional anesthesia

Comparison of the incidence and severity of delirium and biochemical factors after coronary artery bypass grafting with dexmedetomidine: A randomized double-blind placebo-controlled clinical trial study Massoumi, G. Mansouri, M. Khamesipour, S. ARYA Atherosclerosis 2019

IRCT20171104037209N1
bicarbonate
carbon dioxide
creatinine
dexmedetomidine
haloperidol
hemoglobin
oxygen
potassium
sodium
adult
aged
analysis of variance
article
chi square test
clinical trial
controlled study
coronary artery bypass graft
delirium
disease severity
double blind procedure
drug efficacy
female
human
incidence
leukocyte count
major clinical study
male
middle aged
morbidity
mortality
prevalence
questionnaire
randomized controlled trial
Richmond Agitation Sedation Scale
urea nitrogen blood level

Old Habits Die Hard: Antipsychotics for Treatment of Delirium Marcantonio, E. R. Ann Intern Med 2019
Episodes of psychomotor agitation among medical patients: findings from a longitudinal multicentre study Mansutti, I. Venturini, M. Palese, A. Aging Clin Exp Res 2019

Longitudinal
Medical wards
Older
Psychomotor agitation
Risk factors

The 4 'A's test for detecting delirium in acute medical patients: a diagnostic accuracy study MacLullich, A. M. Shenkin, S. D. Goodacre, S. Godfrey, M. Hanley, J. Stiobhairt, A. Lavender, E. Boyd, J. Stephen, J. Weir, C. MacRaild, A. Steven, J. Black, P. Diernberger, K. Hall, P. Tieges, Z. Fox, C. Anand, A. Young, J. Siddiqi, N. Gray, A. Health Technol Assess 2019

4at
Acute hospitals
Cam
Delirium
Dementia
Diagnostic accuracy

Promoting sleep and circadian health may prevent postoperative delirium: A systematic review and meta-analysis of randomized clinical trials Lu, Y. Li, Y. W. Wang, L. Lydic, R. Baghdoyan, H. A. Shi, X. Y. Zhang, H. Sleep Med Rev 2019

Meta-analysis
Postoperative delirium
Sleep promotion
Systematic review
Trial sequential analysis

A Pilot Study of the Use of Dexmedetomidine for the Control of Delirium by Reducing the Serum Concentrations of Brain-Derived Neurotrophic Factor, Neuron-Specific Enolase, and S100B in Polytrauma Patients Li, Y. Yu, Z. X. Ji, M. S. Yan, J. Cai, Y. Liu, J. Yang, H. F. Jin, Z. C. J Intensive Care Med 2019

S100b
brain-derived neurotrophic factor
delirium
dexmedetomidine
neuron-specific enolase
polytrauma

Effectiveness and harms of pharmacological interventions for the treatment of delirium in adults in intensive care units after cardiac surgery: a systematic review Leigh, V. Stern, C. Elliott, R. Tufanaru, C. JBI Database System Rev Implement Rep 2019
Physical Activity and Risk of Postoperative Delirium Lee, S. S. Lo, Y. Verghese, J. J Am Geriatr Soc 2019

cognitive reserve
physical activity
postoperative delirium

Predictive Ability of a Serious Game to Identify Emergency Patients With Unrecognized Delirium Lee, J. S. Tong, T. Tierney, M. C. Kiss, A. Chignell, M. J Am Geriatr Soc 2019

delirium recognition
emergency department
feasibility
serious game
validity

Could Neutrophil-to-Lymphocyte Ratio (NLR) Serve as a Potential Marker for Delirium Prediction in Patients with Acute Ischemic Stroke? A Prospective Observational Study Kotfis, K. Bott-Olejnik, M. Szylinska, A. Rotter, I. J Clin Med 2019

*Crp
*Nihss
*Nlr
*acute brain dysfunction
*leucocytes
*lymphocytes
*neutrophils

C-reactive protein for risk prediction of post-operative delirium and post-operative neurocognitive disorder Knaak, C. Vorderwulbecke, G. Spies, C. Piper, S. K. Hadzidiakos, D. Borchers, F. Brockhaus, W. R. Radtke, F. M. Lachmann, G. Acta Anaesthesiol Scand 2019

C-reactive protein (CRP)
biomarker
inflammation
pathophysiology
post-operative cognitive dysfunction (POCD)
post-operative delirium (POD)
post-operative neurocognitive disorder (NCD)

Clinical EEG slowing correlates with delirium severity and predicts poor clinical outcomes Kimchi, E. Y. Neelagiri, A. Whitt, W. Sagi, A. R. Ryan, S. L. Gadbois, G. Groothuysen, D. Westover, M. B. Neurology 2019
Development of a Risk Score to Predict Postoperative Delirium in Patients With Hip Fracture Kim, E. M. Li, G. Kim, M. Anesth Analg 2019
Assessment of Delirium Using the Confusion Assessment Method in Older Adult Inpatients in Malaysia Khor, H. M. Ong, H. C. Tan, B. K. Low, C. M. Saedon, N. Tan, K. M. Chin, A. V. Kamaruzzaman, S. B. Tan, M. P. Geriatrics (Basel) 2019

Malaysia
confusion
delirium
hospital
inpatient
older

The value of screening for cognition, depression, and frailty in patients referred for TAVI Khan, M. M. Lanctôt, K. L. Fremes, S. E. Wijeysundera, H. C. Radhakrishnan, S. Gallagher, D. Gandell, D. Brenkel, M. C. Hazan, E. L. Docteur, N. G. Herrmann, N. Clinical Interventions in Aging 2019

activity of daily living assessment
aged
article
cognitive defect
cognitive function test
cohort analysis
controlled study
dementia
depression
female
frailty
grip strength
human
incidence
major clinical study
male
mild cognitive impairment
Mini Cog test
mortality rate
multivariate logistic regression analysis
observational study
Patient Health Questionnaire 2
postoperative delirium
prospective study
screening
screening for and managing risk factors in TAVI an interdisciplinary endeavour
timed up and go test
transcatheter aortic valve implantation

Medication Use and Risk of Delirium in Mechanically Ventilated Patients Jin, T. Jin, Y. Lee, S. M. Clin Nurs Res 2019

delirium
mechanical ventilation
medication

Delirium in medical intensive care units: Incidence, subtypes, risk factors, and outcome Jayaswal, A. Sampath, H. Soohinda, G. Dutta, S. Indian Journal of Psychiatry 2019

benzodiazepine
bilirubin
creatinine
adult
article
artificial ventilation
assessment of humans
chronic liver disease
clinical outcome
cohort analysis
Confusion Assessment Method‑Intensive Care Unit
delirium
disease predisposition
female
fever
human
hyperbilirubinemia
hypoxia
incidence
intensive care unit
length of stay
major clinical study
male
medical history
middle aged
mortality
observational study
Richmond Agitation Sedation Scale
risk factor
tobacco use

Risk factors for postoperative delirium after elective major abdominal surgery in elderly patients: A cohort study Janssen, T. L. Steyerberg, E. W. Faes, M. C. Wijsman, J. H. Gobardhan, P. D. Ho, G. H. van der Laan, L. Int J Surg 2019

Abdominal aortic aneurysm
Colorectal carcinoma
Elective
Major abdominal surgery
Postoperative delirium
Risk factors

Prevention of postoperative delirium in elderly patients planned for elective surgery: Systematic review and meta-analysis Janssen, T. L. Alberts, A. R. Hooft, L. Mattace-Raso, F. U. S. Mosk, C. A. Van Der Laan, L. Clinical Interventions in Aging 2019

bupivacaine
clonidine
dexmedetomidine
diazepam
fentanyl
flunitrazepam
gabapentin
haloperidol
ketamine
melatonin
midazolam
morphine
neuroleptic agent
nitrous oxide
olanzapine
oxygen
parecoxib
pethidine
placebo
propofol
sevoflurane
yokukansan
artificial ventilation
bispectral index
blood transfusion
cognitive defect
continuous infusion
disease duration
disease severity
dose response
drug dose comparison
elective surgery
evening dosage
general anesthesia
human
incidence
meta analysis
music therapy
patient controlled analgesia
positive end expiratory pressure
postoperative delirium
postoperative pain
primary prevention
regional anesthesia
review
surgical patient
systematic review

Ramelteon for Prevention of Postoperative Delirium: A Randomized Controlled Trial in Patients Undergoing Elective Pulmonary Thromboendarterectomy Jaiswal, S. J. Vyas, A. D. Heisel, A. J. Ackula, H. Aggarwal, A. Kim, N. H. Kerr, K. M. Madani, M. Pretorius, V. Auger, W. R. Fernandes, T. M. Malhotra, A. Owens, R. L. Crit Care Med 2019
Effect and analysis of ulinastatin combined with thymosin on cardiopulmonary function and delirium in sepsis patients Huanling, S. Rongju, L. Min, J. Pakistan Journal of Pharmaceutical Sciences 2019

adult
article
cardiac index
cardiopulmonary function
controlled study
delirium
drug combination
drug safety
female
human
human tissue
major clinical study
male
oxygenation
palliative therapy
protein blood level
randomized controlled trial
sepsis
CD3 antigen
CD4 antigen
D dimer
endogenous compound
thymosin
ulinastatin

Pre-emptive analgesia with continuous fascia iliaca compartment block reduces postoperative delirium in elderly patients with hip fracture. A randomized controlled trial Hao, J. Dong, B. Zhang, J. Luo, Z. Saudi Med J 2019