What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Cerebrovascular pulsatility indicates preoperative subcortical cognitive impairment and an increased risk for postoperative delirium in elderly patients undergoing elective spine surgery
- Authors
- Saar, A. Müller, J. Veser, Y. Behr, F. Rathmann, E. Schroeder, H. W. S. Flöel, A. Müller, J. U. von Sarnowski, B. Fleischmann, R.
- Year
- 2024
- Journal
- Front Med (Lausanne)
- Abstract
INTRODUCTION: Advances in spine surgery enable safe interventions in elderly patients, but perioperative neurocognitive disorders (pNCD), such as post-operative delirium (POD) and cognitive dysfunction (POCD), remain a serious concern. Pre-operative cognitive impairment is a major risk factor for pNCD. Comprehensive pre-operative cognitive assessments are not feasible in clinical practice, making effective screening methods desirable. This study investigates whether pre-operative cerebrovascular duplex sonography can assess subcortical (vascular) cognitive impairment and the risk for POD. METHODS: This prospective single-center study recruited patients aged ≥60 years scheduled for elective spine surgery at a German university hospital. Patients underwent pre-operative assessments including cognitive abilities (CERAD test battery), structural MRI, and cerebrovascular duplex sonography. POD screening was conducted three times daily for at least 3 days. The primary hypothesis, that the mean pulsatility index (PI) of both internal carotid arteries (ICA) predicts POD risk, was tested using logistic regression. Secondary analyses examined the association between POD risk and ICA flow (time-averaged peak velocities, TAPV) and correlations with cognitive profiles and MRI characteristics. RESULTS: POD occurred in 22% of patients (n = 22/99) within three postoperative days. Patients with POD were significantly older (75.9 ± 5.4 vs. 70.0 ± 6.9 years, p < 0.01) but did not differ by gender (p = 0.51). ICA PI significantly predicted POD risk (OR = 5.46 [95%CI: 1.81-16.49], p = 0.003), which remained significant after adjustment for age and duration of surgery (OR(adj) = 6.38 [95% CI: 1.77-23.03], p = 0.005). TAPV did not inform the POD risk (p = 0.68). ICA PI Pre-operative cognitive scores were significantly associated with ICA PI (mean CERAD score: r = -0.32, p < 0.001). ICA PI was also significantly associated with total white matter lesion volume (τ = 0.19, p = 0.012) and periventricular white matter lesion volume (τ = 0.21, p = 0.007). DISCUSSION: This is the first study to demonstrate that cerebrovascular duplex sonography can assess the risk for POD in elderly spine surgery patients. Increased ICA PI may indicate subcortical impairment, larger white matter lesion load, and lower white matter volume, predisposing factors for POD. Pre-operative cerebrovascular duplex sonography of the ICA is widely available, easy-to-use, and efficient, offering a promising screening method for POD risk. Increased ICA PI could supplement established predictors like age to adjust surgical and peri-operative procedures to individual risk profiles.
- PMID
PMID: 39380730
PMCID: PMC11458395
- Keywords
carotid ultrasound
cognitive impairment
delirium
risk prediction
spine surgery
white matter lesions
- Page(s)
- Volume
- Issue
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| Psychometric evaluation of the family caregiver ICU delirium knowledge questionnaire | Krewulak, K. D. Bull, M. J. Ely, E. W. Stelfox, H. T. Fiest, K. M. | BMC Health Serv Res | 2020 |
Critical care |
| The Impact of Acute Kidney Injury in the Perioperative Period on the Incidence of Postoperative Delirium in Patients Undergoing Coronary Artery Bypass Grafting-Observational Cohort Study | Kotfis, K. Slozowska, J. Listewnik, M. Szylinska, A. Rotter, I. | Int J Environ Res Public Health | 2020 |
Aki |
| Delirium point prevalence studies in inpatient settings: A systematic review and meta-analysis | Koirala, B. Hansen, B. R. Hosie, A. Budhathoki, C. Seal, S. Beaman, A. Davidson, P. M. | J Clin Nurs | 2020 |
delirium |
| Validity and Reliability of the Memorial Delirium Assessment Scale-Thai Version (MDAS-T) for Assessment of Delirium in Palliative Care Patients | Klankluang, W. Pukrittayakamee, P. Atsariyasing, W. Siriussawakul, A. Chanthong, P. Tongsai, S. Tayjasanant, S. | Oncologist | 2020 |
Delirium |
| The Impact of an Attending Intensivist on the Clinical Outcomes of Patients Admitted to the Cardiac Surgical Intensive Care Unit after Coronary Artery Bypass Grafting | Kim, D. J. Sohn, B. Kim, H. Chang, H. W. Lee, J. H. Kim, J. S. Lim, C. Park, K. H. | Korean J Thorac Cardiovasc Surg | 2020 |
Coronary artery bypass grafting |
| Working Collaboratively: Outcomes of Geriatrician Input in Older Patients Undergoing Emergency Laparotomy in a District General Hospital | Khan, K. A. Subramanian, T. Richters, M. Mubarik, A. Saad Abdalla Al-Zawi, A. Thorn, C. C. Chalstrey, S. Gunasekera, S. | Cureus | 2020 |
ageing & frailty |
| Postoperative delirium: the findings from a multidisciplinary survey | Jin, Z. Rahman, A. Pattnaik, S. Smith, M. | Psychogeriatrics | 2020 |
education |
| Postoperative delirium after reconstructive surgery for oral tumor: a retrospective clinical study | Ishibashi-Kanno, N. Takaoka, S. Nagai, H. Okubo-Sato, M. Fukuzawa, S. Uchida, F. Yamagata, K. Yanagawa, T. Bukawa, H. | Int J Oral Maxillofac Surg | 2020 |
Delirium |
| Joining Forces against Delirium - From Organ-System Care to Whole-Human Care | Inouye, S. K. | N Engl J Med | 2020 |
Aged |
| Incidence of and risk factors for postoperative delirium in older adult patients undergoing noncardiac surgery: a prospective study | Iamaroon, A. Wongviriyawong, T. Sura-Arunsumrit, P. Wiwatnodom, N. Rewuri, N. Chaiwat, O. | BMC Geriatr | 2020 |
Collaborative approach |
| Delirium misdiagnosis risk in psychiatry: a machine learning-logistic regression predictive algorithm | Hercus, C. Hudaib, A. R. | BMC Health Serv Res | 2020 |
Delirium |
| Patterns of Potentially Inappropriate Bladder Antimuscarinic Use in People with Dementia: A Retrospective Cohort Study | Green, A. R. Segal, J. Boyd, C. M. Huang, J. Roth, D. L. | Drugs Real World Outcomes | 2020 | |
| Incidence, determinants and consequences of delirium in older patients after transcatheter aortic valve implantation | Goudzwaard, J. A. de Ronde-Tillmans, Mjag de Jager, T. A. J. Lenzen, M. J. Nuis, R. J. van Mieghem, N. M. Daemen, J. de Jaegere, P. P. T. Mattace-Raso, F. U. S. | Age Ageing | 2020 |
aortic stenosis |
| Neuromonitoring of delirium with quantitative pupillometry in sedated mechanically ventilated critically ill patients | Favre, E. Bernini, A. Morelli, P. Pasquier, J. Miroz, J. P. Abed-Maillard, S. Ben-Hamouda, N. Oddo, M. | Crit Care | 2020 |
Cholinergic |
| Cognitive Outcomes of Long-term Benzodiazepine and Related Drug (BDZR) Use in People Living With Mild to Moderate Alzheimer's Disease: Results From NILVAD | Dyer, A. H. Murphy, C. Lawlor, B. Kennelly, S. P. | J Am Med Dir Assoc | 2020 |
Dementia |
| 'Nonagenarians' with a hip fracture: is a different orthogeriatric treatment strategy necessary? | de Groot, R. Nijmeijer, W. S. Folbert, E. C. Vollenbroek-Hutten, M. M. R. Hegeman, J. H. | Arch Osteoporos | 2020 |
Frail elderly |
| Comparison of single minimum dose administration of dexmedetomidine and midazolam for prevention of emergence delirium in children: a randomized controlled trial | Cho, E. A. Cha, Y. B. Shim, J. G. Ahn, J. H. Lee, S. H. Ryu, K. H. | J Anesth | 2020 |
Dexmedetomidine |
| Innovative care models across settings: Providing nursing care to older adults | Cacchione, P. Z. | Geriatr Nurs | 2020 |
Evercare/Optum |
| Is the bispectral index monitoring protective against postoperative cognitive decline? A systematic review with meta-analysis | Bocskai, T. Kovacs, M. Szakacs, Z. Gede, N. Hegyi, P. Varga, G. Pap, I. Toth, I. Revesz, P. Szanyi, I. Nemeth, A. Gerlinger, I. Karadi, K. Lujber, L. | PLoS One | 2020 |
Anesthesia |
| Postanesthesia care unit delirium following robot-assisted vs open retropubic radical prostatectomy: A prospective observational study | Beck, S. Hoop, D. Ragab, H. Rademacher, C. Messner-Schmitt, A. von Breunig, F. Haese, A. Graefen, M. Zollner, C. Fischer, M. | Int J Med Robot | 2020 |
Trendelenburg position |
| The impact of Hospital Elder Life Program interventions, on 30-day readmission Rates of older hospitalized patients | Zachary, W. Kirupananthan, A. Cotter, S. Barbara, G. H. Cooke, R. C., 3rd Sipho, M. | Arch Gerontol Geriatr | 2020 |
Cost savings |
| Prevalence and risk factors for postoperative delirium in patients with colorectal carcinoma: a systematic review and meta-analysis | Yang, Z. Wang, X. F. Yang, L. F. Fang, C. Gu, X. K. Guo, H. W. | Int J Colorectal Dis | 2020 |
Coloretal cancer |
| Incidence, risk factors, and outcomes for sepsis-associated delirium in patients with mechanical ventilation: A sub-analysis of a multicenter randomized controlled trial | Yamamoto, T. Mizobata, Y. Kawazoe, Y. Miyamoto, K. Ohta, Y. Morimoto, T. Yamamura, H. | Journal of Critical Care | 2020 |
fentanyl |
| Effects of different BP management strategies on postoperative delirium in elderly patients undergoing hip replacement: A single center randomized controlled trial | Xu, X. Hu, X. Wu, Y. Li, Y. Zhang, Y. Zhang, M. Yang, Q. | J Clin Anesth | 2020 |
Blood pressure |
| Preoperative prognostic nutritional index predicts postoperative delirium in elderly patients after hip fracture surgery | Xing, H. Xiang, D. Li, Y. Ji, X. Xie, G. | Psychogeriatrics | 2020 |
elderly |
| The effects of early femoral nerve block intervention on preoperative pain management and incidence of postoperative delirium geriatric patients undergoing trochanteric femur fracture surgery: A randomized controlled trial | Uysal, A. I. Altiparmak, B. Yasar, E. Turan, M. Canbek, U. Yilmaz, N. Gumus Demirbilek, S. | Ulus Travma Acil Cerrahi Derg | 2020 | |
| A smartphone-based test for the assessment of attention deficits in delirium: A case-control diagnostic test accuracy study in older hospitalised patients | Tieges, Z. Stott, D. J. Shaw, R. Tang, E. Rutter, L. M. Nouzova, E. Duncan, N. Clarke, C. Weir, C. J. Assi, V. Ensor, H. Barnett, J. H. Evans, J. Green, S. Hendry, K. Thomson, M. McKeever, J. Middleton, D. G. Parks, S. Walsh, T. Weir, A. J. Wilson, E. Qua | PLoS One | 2020 | |
| A 'real-world' analysis of risk factors for post liver transplant delirium and the effect on length of stay | Tavabie, O. D. Colwill, M. Adamson, R. McPhail, M. J. W. Bernal, W. Jassem, W. Prachialias, A. Heneghan, M. Aluvihare, V. R. Agarwal, K. | Eur J Gastroenterol Hepatol | 2020 | |
| Intraoperative hypotension and delirium in patients with hip fracture | Tantardini, V. Roca, F. Bahri, O. Compere, V. Dujardin, F. Chassagne, P. | Geriatr Psychol Neuropsychiatr Vieil | 2020 |
anaesthesia |
| Evaluation of emergence agitation after general anaesthesia in rhinoplasty patients: Inhalation anaesthesia versus total intravenous anaesthesia | Talih, G. Yüksek, A. Şahin, E. | American Journal of Otolaryngology - Head and Neck Medicine and Surgery | 2020 |
adult |
| Implementation of a multiprofessional, multicomponent delirium management guideline in two intensive care units, and its effect on patient outcomes and nurse workload: a pre-post design retrospective cohort study | Schubert, M. Bettex, D. Steiger, P. Schurch, R. Haller, A. Bogdanovic, J. Garcia Nunez, D. Schwarz, U. Siegemund, M. | Swiss Med Wkly | 2020 | |
| Cerebrospinal Fluid Levels of Interleukin-8 in Delirium, Dementia, and Cognitively Healthy Patients | Sajjad, M. U. Blennow, K. Knapskog, A. B. Idland, A. V. Chaudhry, F. A. Wyller, T. B. Zetterberg, H. Watne, L. O. | J Alzheimers Dis | 2020 |
Alzheimer’s disease |
| Prehospital Anticholinergic Burden Is Associated With Delirium but Not With Mortality in a Population of Acutely Ill Medical Patients | Rigor, J. Rueff Rato, I. Ferreira, P. M. Pereira, R. Ribeiro, C. Teixeira, D. Mesquita Oliveira, P. Silva, A. M. Pereira, S. Costa, I. Ferreira, P. Sequeira, M. Monteiro-Soares, M. Martins-Mendes, D. | J Am Med Dir Assoc | 2020 |
Anticholinergic |
| Impact of Vitamin C and Thiamine Administration on Delirium-Free Days in Patients with Septic Shock | Park, J. E. Shin, T. G. Jo, I. J. Jeon, K. Suh, G. Y. Park, M. Won, H. Chung, C. R. Hwang, S. Y. | J Clin Med | 2020 |
delirium |
| Evaluation of an updated sedation protocol to reduce benzodiazepines in a pediatric intensive care unit | Michel, J. Hofbeck, M. Peper, A. K. Kumpf, M. Neunhoeffer, F. | Curr Med Res Opin | 2020 |
Cardiac surgery |
| A qualitative exploration of the views of patients and their relatives regarding interventions to minimize the distress related to postoperative delirium | Meilak, C. Biswell, E. Willis, R. Partridge, J. Dhesi, J. | Int J Geriatr Psychiatry | 2020 |
aged |
| Incidence and risk factors of postoperative delirium in elderly patients undergoing urological surgery: A multi-institutional prospective study | Matsuki, M. Tanaka, T. Takahashi, A. Inoue, R. Hotta, H. Itoh, N. Taguchi, K. Kato, R. Kobayashi, K. Masumori, N. | Int J Urol | 2020 |
elderly patients |
| Still Predicting Delirium After All These Years | Marcantonio, ER | Anesth Analg | 2020 | |
| Ketamine sedation in mechanically ventilated patients: A systematic review and meta-analysis | Manasco, A. T. Stephens, R. J. Yaeger, L. H. Roberts, B. W. Fuller, B. M. | Journal of Critical Care | 2020 |
fentanyl |
| A Study of the Psychometric Properties of the “Stanford Proxy Test for Delirium” (S-PTD): A New Screening Tool for the Detection of Delirium | Maldonado, J. R. Sher, Y. I. Benitez-Lopez, M. A. Savant, V. Garcia, R. Ament, A. De Guzman, E. | Psychosomatics | 2020 |
adult |
| Risk factors for postoperative delirium after colorectal surgery: a systematic review and meta-analysis | Lee, S. H. Lim, S. W. | Int J Colorectal Dis | 2020 |
Colorectal surgery |
| Results from a double blinded, randomized, placebo-controlled, feasibility trial of melatonin for the treatment of delirium in older medical inpatients | Lange, P. W. Clayton-Chubb, D. I. Watson, R. Maier, A. B. | Intern Med J | 2020 |
Delirium |
| Risk factors and outcomes among delirium subtypes in adult ICUs: A systematic review | Krewulak, K. D. Stelfox, H. T. Ely, E. W. Fiest, K. M. | J Crit Care | 2020 |
Critical care |
| Survey of analgesia and sedation in pediatric intensive care units in Japan | Koizumi, T. Kurosawa, H. | Pediatr Int | 2020 |
analgesia |
| Association of neuronal repair biomarkers with delirium among survivors of critical illness | Hayhurst, C. J. Patel, M. B. McNeil, J. B. Girard, T. D. Brummel, N. E. Thompson, J. L. Chandrasekhar, R. Ware, L. B. Pandharipande, P. P. Ely, E. W. Hughes, C. G. | Journal of Critical Care | 2020 |
NCT00392795 |
| Dexmedetomidine's Relationship to Delirium in Patients Undergoing Cardiac Surgery: A Systematic Review | Halpin, E. Inch, H. O'Neill, M. | Crit Care Nurs Q | 2020 | |
| Management of delirium at an academic medical center: Plans for antipsychotic prescribing upon discharge | Halavonich, L. Robert, S. McGraw, D. Weeda, E. Mullinax, K. Bass, B. | Ment Health Clin | 2020 |
antipsychotic |
| Association Between Level of Arousal and 30-Day Survival in Acutely Ill Older Adults | Garcez, F. B. Jacob-Filho, W. Avelino-Silva, T. J. | J Am Med Dir Assoc | 2020 |
Delirium |
| Drug therapy for delirium in terminally ill adults | Finucane, A. M. Jones, L. Leurent, B. Sampson, E. L. Stone, P. Tookman, A. Candy, B. | Cochrane Database Syst Rev | 2020 | |
| Delirium in patients with hip fracture is associated with increased heart rate variability | Ernst, G. Watne, L. O. Rostrup, M. Neerland, B. E. | Aging Clin Exp Res | 2020 |
Autonomic nervous system |
| Risk factors for delirium after esophagectomy | Dezube, A. R. Bravo-Iniguez, C. E. Yelamanchili, N. De Leon, L. E. Tarascio, J. Jaklitsch, M. T. Wee, J. O. | J Surg Oncol | 2020 |
delirium |
| Delirium in a Tertiary PICU: Risk Factors and Outcomes | Dervan, L. A. Di Gennaro, J. L. Farris, R. W. D. Watson, R. S. | Pediatr Crit Care Med | 2020 | |
| Validity and Reliability of the Brazilian Portuguese Version of the Pediatric Confusion Assessment Method for the ICU | de Castro, R. E. V. Prata-Barbosa, A. de Magalhaes-Barbosa, M. C. Cunha, Ajlad Cheniaux, E. Smith, H. A. B. | Pediatr Crit Care Med | 2020 | |
| Outcomes for patients with delirium receiving hospital-in-the-home treatment: An Australian perspective | Chia, J. Eeles, E. M. Tattam, K. Yerkovich, S. | Australas J Ageing | 2020 |
delirium |
| A software to prevent delirium in hospitalised older adults: development and feasibility assessment | Alvarez, E. A. Garrido, M. Ponce, D. P. Pizarro, G. Cordova, A. A. Vera, F. Ruiz, R. Fernandez, R. Velasquez, J. D. Tobar, E. Salech, F. | Age Ageing | 2020 |
delirium |
| Cholinesterase alterations in delirium after cardiosurgery: a German monocentric prospective study | Adam, E. H. Haas, V. Lindau, S. Zacharowski, K. Scheller, B. | BMJ Open | 2020 |
acetylcholinesterase |
| Cornell Assessment of Pediatric Delirium: a valid, rapid, observational tool for screening delirium in the PICU* | Traube, C. Silver, G. Kearney, J. Patel, A. Atkinson, T. M. Yoon, M. J. Halpert, S. Augenstein, J. Sickles, L. E. Li, C. Greenwald, B. | Crit Care Med | 2014 |
Adolescent |
| The Preschool Confusion Assessment Method for the ICU: Valid and Reliable Delirium Monitoring for Critically Ill Infants and Children | Smith, H. A. Gangopadhyay, M. Goben, C. M. Jacobowski, N. L. Chestnut, M. H. Savage, S. Rutherford, M. T. Denton, D. Thompson, J. L. Chandrasekhar, R. Acton, M. Newman, J. Noori, H. P. Terrell, M. K. Williams, S. R. Griffith, K. Cooper, T. J. Ely, E. W. F | Crit Care Med | 2016 |
Child, Preschool |
| Diagnosing delirium in critically ill children: Validity and reliability of the Pediatric Confusion Assessment Method for the Intensive Care Unit | Smith, H. A. Boyd, J. Fuchs, D. C. Melvin, K. Berry, P. Shintani, A. Eden, S. K. Terrell, M. K. Boswell, T. Wolfram, K. Sopfe, J. Barr, F. E. Pandharipande, P. P. Ely, E. W. | Crit Care Med | 2011 |
Child |
| Development and psychometric evaluation of the pediatric anesthesia emergence delirium scale | Sikich, N. Lerman, J. | Anesthesiology | 2004 |
*Anesthesia Recovery Period |
| From Pediatrics to Geriatrics: Toward a Unified Standardized Screening Tool for Delirium: A Thought Experiment | Schieveld, J. N. van Zwieten, J. J. | Crit Care Med | 2016 |
Adult |
| Diagnostic considerations regarding pediatric delirium: a review and a proposal for an algorithm for pediatric intensive care units | Schieveld, J. N. van der Valk, J. A. Smeets, I. Berghmans, E. Wassenberg, R. Leroy, P. L. Vos, G. D. van Os, J. | Intensive Care Med | 2009 |
Age Factors |
| On the utility of diagnostic instruments for pediatric delirium in critical illness: an evaluation of the Pediatric Anesthesia Emergence Delirium Scale, the Delirium Rating Scale 88, and the Delirium Rating Scale-Revised R-98 | Janssen, N. J. Tan, E. Y. Staal, M. Janssen, E. P. Leroy, P. L. Lousberg, R. van Os, J. Schieveld, J. N. | Intensive Care Med | 2011 |
*Anesthesia Recovery Period |
| Validation of the SOS-PD scale for assessment of pediatric delirium: a multicenter study | Ista, E. van Beusekom, B. van Rosmalen, J. Kneyber, M. C. J. Lemson, J. Brouwers, A. Dieleman, G. C. Dierckx, B. de Hoog, M. Tibboel, D. van Dijk, M. | Crit Care | 2018 |
Adolescent |
| Sophia Observation withdrawal Symptoms-Paediatric Delirium scale: A tool for early screening of delirium in the PICU | Ista, E. Te Beest, H. van Rosmalen, J. de Hoog, M. Tibboel, D. van Beusekom, B. van Dijk, M. | Aust Crit Care | 2018 |
Adolescent |
| Psychometric evaluation of the Sophia Observation withdrawal symptoms scale in critically ill children | Ista, E. de Hoog, M. Tibboel, D. Duivenvoorden, H. J. van Dijk, M. | Pediatr Crit Care Med | 2013 |
Adolescent |
| Clinical recommendations for pain, sedation, withdrawal and delirium assessment in critically ill infants and children: an ESPNIC position statement for healthcare professionals | Harris, J. Ramelet, A. S. van Dijk, M. Pokorna, P. Wielenga, J. Tume, L. Tibboel, D. Ista, E. | Intensive Care Med | 2016 |
Child |
| Assessment scales for delirium: A review | Grover, S. Kate, N. | World J Psychiatry | 2012 |
Cognition |
| Diagnostic accuracy of delirium diagnosis in pediatric intensive care: a systematic review | Daoud, A. Duff, J. P. Joffe, A. R. Alberta Sepsis, Network | Crit Care | 2014 |
Anesthesia/adverse effects |
| Diagnostic accuracy of delirium diagnosis in pediatric intensive care: a systematic review | Daoud, A. Duff, J. P. Joffe, A. R. Alberta Sepsis, Network | Crit Care | 2014 |
Anesthesia/adverse effects |
| Delirium is prevalent in older hospital inpatients and associated with adverse outcomes: Results of a prospective multi-centre study on World Delirium Awareness Day | Welch, C. McCluskey, L. Wilson, D. Chapman, G. E. Jackson, T. A. Treml, J. Davis, D. Cunningham, E. Copeland, C. Quinn, T. Pinkney, T. Mahida, R. Nightingale, P. Richardson, S. Todd, O. Willott, R. Torsney, K. Ni Lochlainn, M. Giridharan, K. Cox, N. Masol | BMC Medicine | 2019 |
adult |
| Olanzapine Versus Haloperidol for Treatment of Delirium in Patients with Advanced Cancer: A Phase III Randomized Clinical Trial | van der Vorst, Mjdl Neefjes, E. C. W. Boddaert, M. S. A. Verdegaal, Batt Beeker, A. Teunissen, S. C. C. Beekman, A. T. F. Wilschut, J. A. Berkhof, J. Zuurmond, W. W. A. Verheul, H. M. W. | Oncologist | 2019 |
Advanced cancer |
| Diverging Awareness of Postoperative Delirium and Cognitive Dysfunction in German Health Care Providers | Sturm, H. Wildermuth, R. Stolz, R. Bertram, L. Eschweiler, G. W. Thomas, C. Rapp, M. Joos, S. | Clin Interv Aging | 2019 |
Pocd |
| An evaluation of the Danish version of the Pediatric Anesthesia Emergence Delirium scale | Simonsen, B. Y. Skovby, P. Lisby, M. | Acta Anaesthesiol Scand | 2019 | |
| Incidence and Risk Factors for Delirium in Elderly Patients with Critical Limb Ischaemia | Roijers, J. P. Rakke, Y. S. Hopmans, C. J. Buimer, M. G. de Groot, H. G. W. Ho, G. H. Veen, E. J. Mulder, P. G. H. van der Laan, L. | Eur J Vasc Endovasc Surg | 2019 |
Critical limb ischaemia |
| Initiative for Prevention and Early Identification of Delirium in Medical-Surgical Units: Lessons Learned in the Past Five Years | Rohatgi, N. Weng, Y. Bentley, J. Lansberg, M. G. Shepard, J. Mazur, D. Ahuja, N. Hopkins, J. | Am J Med | 2019 |
Delirium |
| Elevation of Preoperative Ammonia Level Is Not Associated With the Incidence of Postoperative Delirium in Patients with Liver Transplantation: A Propensity Score Matching Analysis | Ri, H. S. Choi, Y. J. Park, J. Y. Jin, S. J. Lee, Y. S. Son, J. M. Yoon, S. Z. Shin, H. W. Choi, B. H. Lee, T. B. | Transplant Proc | 2019 | |
| Fluctuations of consciousness after stroke: Associations with the confusion assessment method for the intensive care unit (CAM-ICU) and potential undetected delirium | Reznik, M. E. Daiello, L. A. Thompson, B. B. Wendell, L. C. Mahta, A. Potter, N. S. Yaghi, S. Levy, M. M. Fehnel, C. R. Furie, K. L. Jones, R. N. | J Crit Care | 2019 |
Consciousness |
| Postoperative serum albumin decrease independently predicts delirium in elderly subjects after total joint arthroplasty | Qi, J. Liu, C. Chen, L. Chen, J. | Curr Pharm Des | 2019 |
Postoperative delirium |
| Dexmedetomidine versus propofol sedation in reducing delirium among older adults in the ICU: A systematic review and meta-analysis | Pereira, J. V. Sanjanwala, R. M. Mohammed, M. K. Le, M. L. Arora, R. C. | Eur J Anaesthesiol | 2019 | |
| Delirium Rates in Advanced Cancer Patients Admitted to Different Palliative Care Settings: Does It Make the Difference? | Pallotti, M. C. Lopez-Fidalgo Ph, D. J. Biasco, G. Celin, D. Centeno, C. Paragona, M. Moroni, M. Noguera, A. | J Palliat Med | 2019 |
cancer patients |
| Randomized Controlled Trial of Enhanced Recovery Program Dedicated to Elderly Patients after Colorectal Surgery | Ostermann, S. Morel, P. Chalé, J. J. Bucher, P. Konrad, B. Meier, R. P. H. Ris, F. Schiffer, E. R. C. | Diseases of the Colon and Rectum | 2019 |
NCT01646190 |
| The effect of ketamine on emergence agitation in children: A systematic review and meta-analysis | Ng, K. T. Sarode, D. Lai, Y. S. Teoh, W. Y. Wang, C. Y. | Paediatr Anaesth | 2019 |
emergence agitation |
| BIS index monitoring and perioperative neurocognitive disorders in older adults: a systematic review and meta-analysis | Miao, M. Xu, Y. Sun, M. Chang, E. Cong, X. Zhang, J. | Aging Clin Exp Res | 2019 |
Bispectral index |
| Plasma biomarkers of inflammation, coagulation, and brain injury as predictors of delirium duration in older hospitalized patients | McNeil, J. B. Hughes, C. G. Girard, T. Ware, L. B. Ely, E. W. Chandrasekhar, R. Han, J. H. | PLoS One | 2019 | |
| Randomized controlled trial of acupuncture to prevent emergence delirium in children undergoing myringotomy tube placement | Martin, C. S. Yanez, N. D. Treggiari, M. M. Piper, L. Cusick, J. Lalwani, K. | Minerva Anestesiol | 2019 | |
| Detecting delirium in patients with acute stroke: a systematic review of test accuracy | Mansutti, I. Saiani, L. Palese, A. | BMC Neurol | 2019 |
Instruments |
| Associations of 4AT with mobility, length of stay and mortality in hospital and discharge destination among patients admitted with hip fractures | Lisk, R. Yeong, K. Enwere, P. Jenkinson, J. Robin, J. Irvin-Sellers, M. Fluck, D. Osmani, A. Sharmin, R. Sharma, P. Fry, C. H. Han, T. S. | Age Ageing | 2019 |
Nhs |
| Effectiveness of an advanced practice nurse-led delirium education and training programme | Lieow, J. L. M. Chen, F. S. M. Song, G. Tang, P. S. Kowitlawakul, Y. Mukhopadhyay, A. | Int Nurs Rev | 2019 |
Advanced Practice Nurses |
| Comparison of emergence agitation between succinylcholine and rocuronium-sugammadex in adults following closed reduction of a nasal bone fracture: A prospective randomized controlled trial | Lee, S. J. Sung, T. Y. Cho, C. K. | BMC Anesthesiology | 2019 |
adult |
| Risk factors for post-intensive care syndrome: A systematic review and meta-analysis | Lee, M. Kang, J. Jeong, Y. J. | Aust Crit Care | 2019 |
Intensive care units |
| Effect of Perioperative Low-Dose Dexmedetomidine on Postoperative Delirium After Living-Donor Liver Transplantation: A Randomized Controlled Trial | Lee, H. Yang, S. M. Chung, J. Oh, H. W. Yi, N. J. Suh, K. S. Oh, S. Y. Ryu, H. G. | Transplant Proc | 2019 | |
| The Association of Perioperative Serum Lactate Levels with Postoperative Delirium in Elderly Trauma Patients | Lee, C. Lee, J. Cho, H. Song, J. Jung, H. Ma, X. Hwang, J. | BioMed Research International | 2019 |
lactic acid |
| Frailty defined by 19 items as a predictor of short-term functional recovery in patients with hip fracture | Inoue, T. Misu, S. Tanaka, T. Kakehi, T. Kakiuchi, M. Chuman, Y. Ono, R. | Injury | 2019 |
aged |
| Using language descriptors to recognise delirium: a survey of clinicians and medical coders to identify delirium-suggestive words | Holmes, N. E. Amjad, S. Young, M. Berlowitz, D. J. Bellomo, R. | Crit Care Resusc | 2019 |
*Clinical Coding |
| Diagnostic test accuracy meta-analysis of PRE-DELIRIC (PREdiction of DELIRium in ICu patients): A delirium prediction model in intensive care practice | Ho, M. H. Chen, K. H. Montayre, J. Liu, M. F. Chang, C. C. Traynor, V. Shen Hsiao, S. T. Chang, H. R. Chiu, H. Y. | Intensive Crit Care Nurs | 2019 |
Delirium |
| Delirium management: Let's get physical? A systematic review and meta-analysis | Haley, M. N. Casey, P. Kane, R. Y. Darzins, P. Lawler, K. | Australas J Ageing | 2019 |
delirium |
| Delirium post-cardiac surgery: Incidence and associated factors | Habeeb-Allah, A. Alshraideh, J. A. | Nurs Crit Care | 2019 |
associated factors |
| EEG Correlates of Delirium in Children and Young Adults With CD19-Directed CAR T Cell Treatment-Related Neurotoxicity | Gust, J. Annesley, C. E. Gardner, R. A. Bozarth, X. | J Clin Neurophysiol | 2019 | |
| Process of implementing and delivering the Prevention of Delirium system of care: a mixed method preliminary study | Godfrey, M. Green, J. Smith, J. Cheater, F. Inouye, S. K. Hurst, K. Young, J. | BMC Geriatr | 2019 |
Delirium prevention |