Delirium Bibliography

Delirium Bibliography books graphicWhat is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!

How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.

Reference Information

Title
Does Melatonin Decrease the Use of As-Needed Antipsychotics or Benzodiazepines in Noncritically Ill Hospitalized Patients? A Multicenter Retrospective Cohort Study
Authors
Dobry, P. Poparad-Stezar, A. Bacon, O. Boji, S. Giuliano, C.
Year
2024
Journal
J Integr Complement Med
Abstract

Background: Delirium is a common neuropsychiatric syndrome without an FDA-approved treatment. Commonly used modalities show little improvement in outcomes; therefore, prevention efforts are imperative. Abnormalities in the sleep/wake cycle have been linked to delirium, and melatonin has been proposed to replace the hypothesized low levels of endogenous melatonin and restore sleep/wake cycle synchronization. Objectives: The primary objective of this study was to evaluate the association between melatonin, benzodiazepines (BZDs) or zolpidem (ZLP), and the use of as-needed antipsychotics and BZDs for delirium in noncritically ill adult patients. Methods: This was a multicenter retrospective cohort study of noncritically ill adult patients admitted to two separate health systems from August 2012 to December 2018 receiving either melatonin or nonmelatonin medications (ZLP or BZDs) for sleep. The coprimary endpoint was the proportion of patients receiving a pro re nata (PRN) antipsychotic or BZD 5 days from the patient’s first dose of melatonin, BZD, or ZLP. Secondary outcomes included evaluation of the coprimary outcome in patients 65 years of age or older, total number of PRN antipsychotic and BZD doses, and length of stay. Results: Two hundred and twenty-five patients were included in the final analysis. Administration of BZD or ZLP was associated with a higher risk of subsequent BZD administration as compared with melatonin (OR 2.78, 95% CI 1.2-1.87) and ZLP (OR 2.78, 95% CI 1.25-6.17). BZD or ZLP had no impact on PRN antipsychotic use compared with melatonin (OR 1.09, 95% CI 0.51-2.35) and ZLP (OR 1.16, 95% CI 0.56-2.4). Conclusion: Melatonin use was found to be associated with a significant decrease in PRN BZD use in noncritically ill patients hospitalized on general floors; however, there was no observed association with overall PRN antipsychotic use. These results suggest that using melatonin may help decrease utilization of medications commonly used to manage delirium.

PMID

PMID: 37976107

Keywords

Humans
*Melatonin/administration & dosage/therapeutic use
Retrospective Studies
Male
Female
*Antipsychotic Agents/administration & dosage/therapeutic use
Middle Aged
Aged
*Benzodiazepines/administration & dosage/therapeutic use
*Delirium/drug therapy/epidemiology/prevention & control
Zolpidem/therapeutic use/administration & dosage
Adult
Hospitalization/statistics & numerical data
Hypnotics and Sedatives/administration & dosage/therapeutic use
Aged, 80 and over
antipsychotics
benzodiazepines
delirium
melatonin
zolpidem

Page(s)
Issue

Search:
Total Records Found: 6289, showing 100 per page
TitleAuthorsJournalYearKeywords
American Society for Enhanced Recovery and Perioperative quality initiative joint consensus statement on the role of neuromonitoring in perioperative outcomes: Electroencephalography Chan, M. T. V. Hedrick, T. L. Egan, T. D. García, P. S. Koch, S. Purdon, P. L. Ramsay, M. A. Miller, T. E. McEvoy, M. D. Gan, T. J. Hughes, C. G. Boncyk, C. S. Culley, D. J. Fleisher, L. A. Leung, J. M. McDonagh, D. L. Thiele, R. H. Shaw, A. Bartels, K. Anesthesia and Analgesia 2020

anesthesiologist
article
awareness
comparative effectiveness
consensus
electroencephalography monitoring
human
intravenous anesthesia
meta analysis
neuromonitoring
postoperative delirium
prevention
surgical mortality
systematic review
waveform
anesthetic gas

Evidence-based clinical practice guidelines for the management of sedoanalgesia and delirium in critically ill adult patients Celis-Rodríguez, E. Díaz Cortés, J. C. Cárdenas Bolívar, Y. R. Carrizosa González, J. A. Pinilla, D. I. Ferrer Záccaro, L. E. Birchenall, C. Caballero López, J. Argüello, B. M. Castillo Abrego, G. Castorena Arellano, G. Dueñas Castell, C. Jáure Med Intensiva 2020

Agitación
Agitation
Analgesia
Clinical practice guidelines
Critical care
Cuidado intensivo
Delirium
Dolor
Guía de práctica clínica
Pain
Sedación
Sedation

Patient care during the COVID-19 pandemic: do not leave delirium behind Castro, R. E. V. Garcez, F. B. Avelino-Silva, T. J. Braz J Psychiatry 2020
The financial and social costs of delirium Caplan, G. A. Teodorczuk, A. Streatfeild, J. Agar, M. R. European Geriatric Medicine 2020

cost control
cost of illness
delirium
disability-adjusted life year
economic status
financial management
health care cost
home care
hospital discharge
human
long term care
priority journal
review
social aspect
systematic review

Clinical impression for identification of vulnerable older patients in the emergency department Calf, A. H. Lubbers, S. van den Berg, A. A. van den Berg, E. Jansen, C. J. van Munster, B. C. de Rooij, S. E. Ter Maaten, J. C. Eur J Emerg Med 2020
Is Delirium Pediatric Confusion Assessment Method Tools Confiable? Caino de Oliveira, F. R. Ribeiro de Araujo, O. Brunow de Carvalho, W. Pediatr Crit Care Med 2020

Brazil
Child
Delirium
Humans
Intensive Care Units
Reproducibility of Results

Research in brief: Inpatient hip fractures and nomenclature of delirium and acute encephalopathy Cacciottolo, T. M. Ferrigan, L. Clin Med (Lond) 2020
Prolonged Confusional state as first manifestation of COVID-19 Butt, I. Sawlani, V. Geberhiwot, T. Ann Clin Transl Neurol 2020

Covid-19
Delirium
Neuropathology
SARS-CoV-2

Delirium After Withdrawal From Valerian Root: A Case Report Burke, H. Jiang, S. Chatham, P. Stern, T. A. Psychosomatics 2020
Deciphering delirium through semantics: a selective synopsis Bugiani, O. Neurol Sci 2020

Ageing
Delirium
Encephalopathy
Semantics

Predicting incident delirium diagnoses using data from primary-care electronic health records Bowman, K. Jones, L. Masoli, J. Mujica-Mota, R. Strain, D. Butchart, J. Valderas, J. M. Fortinsky, R. H. Melzer, D. Delgado, J. Age Ageing 2020

at home
confusion
delirium
medical records
older people
predictive model

Comparison of Self-Reported and Behavioral Pain Assessment Tools in Critically Ill Patients Bouajram, R. H. Sebat, C. M. Love, D. Louie, E. L. Wilson, M. D. Duby, J. J. J Intensive Care Med 2020

Behavioral Pain Scale
Critical Care Pain Observation Tool
Numeric Rating Scale
critical care
delirium
pain
self-reported pain

Practical Training of Anesthesia Clinicians in Electroencephalogram-Based Determination of Hypnotic Depth of General Anesthesia Bombardieri, A. M. Wildes, T. S. Stevens, T. Wolfson, M. Steinhorn, R. Ben Abdallah, A. Sleigh, J. Avidan, M. S. Anesth Analg 2020

Anesthesia, Inhalation
Anesthesiologists/ education/psychology
Anesthesiology/ education
Clinical Competence
Consciousness/ drug effects
Education, Medical, Continuing
Educational Measurement
Educational Status
Electroencephalography
Health Knowledge, Attitudes, Practice
Humans
Inservice Training
Intraoperative Neurophysiological Monitoring/ methods
Observer Variation
Pragmatic Clinical Trials as Topic
Predictive Value of Tests
Program Evaluation
Recognition, Psychology

A multisite study of nurse-reported perceptions and practice of ABCDEF bundle components Boehm, L. M. Pun, B. T. Stollings, J. L. Girard, T. D. Rock, P. Hough, C. L. Hsieh, S. J. Khan, B. A. Owens, R. L. Schmidt, G. A. Smith, S. Ely, E. W. Intensive Crit Care Nurs 2020

ABCDEF bundle
Implementation
Intensive care unit
Interprofessional
Nurse

Cognitive impairment, clinical symptoms and functional disability in patients emerging from the minimally conscious state Bodien, Y. G. Martens, G. Ostrow, J. Sheau, K. Giacino, J. T. NeuroRehabilitation 2020

adult
article
brain injury
clinical protocol
cognitive defect
confusion assessment protocol
disability rating scale
female
functional disease
human
major clinical study
male
minimally conscious state
observational study
rating scale
retrospective study
symptom
traumatic brain injury

Effect of intravenous iron on functional outcomes in hip fracture: a randomised controlled trial Bielza, R. Llorente, J. Thuissard, I. J. Andreu-Vázquez, C. Blanco, D. Sanjurjo, J. López, N. Herráez, M. R. Molano, C. Morales, A. Arias, E. Neira, M. Lung, A. Escalera, J. Portillo, L. Larrubia, Y. García, C. Zambrana, F. Gómez Cerezo, J. Age Ageing 2020

anaemia
delirium
functional outcomes
hip fracture
intravenous iron

Tapering with Pharmaceutical GHB or Benzodiazepines for Detoxification in GHB-Dependent Patients: A Matched-Subject Observational Study of Treatment-as-Usual in Belgium and The Netherlands Beurmanjer, H. Luykx, J. J. De Wilde, B. van Rompaey, K. Buwalda, V. J. A. De Jong, C. A. J. Dijkstra, B. A. G. Schellekens, A. F. A. CNS Drugs 2020
Clinical characteristics and outcomes of inpatients with neurologic disease and COVID-19 in Brescia, Lombardy, Italy Benussi, A. Pilotto, A. Premi, E. Libri, I. Giunta, M. Agosti, C. Alberici, A. Baldelli, E. Benini, M. Bonacina, S. Brambilla, L. Caratozzolo, S. Cortinovis, M. Costa, A. Piccinelli, S. C. Cottini, E. Cristillo, V. Delrio, I. Filosto, M. Gamba, M. Gazzina Neurology 2020
Palliative sedation: beliefs and decision-making among Spanish palliative care physicians Benítez-Rosario, M. A. Ascanio-León, B. Support Care Cancer 2020

Cancer patients
Deep sedation
Dying patients
Palliative sedation
Physicians’ opinions
Survey

A Tunisian version of the confusion assessment method for the intensive care unit (CAM-ICU): translation and validation Ben Saida, I. Kortli, S. Amamou, B. Kacem, N. Ghardallou, M. Ely, E. W. Ben Saad, H. Boussarsar, M. BMC Psychiatry 2020

Critical illness
Delirium
North Africa
Translations

'Socialised care futility' in the care of older people in hospital who call out repetitively: An ethnographic study Beaver, J. Goldberg, S. E. Edgley, A. Harwood, R. H. Int J Nurs Stud 2020

Acute hospitals
Agitation
Calling out
Delirium
Dementia
Ethnography
Mixed-methods research

Delirium in COVID-19: A case series and exploration of potential mechanisms for central nervous system involvement Beach, S. R. Praschan, N. C. Hogan, C. Dotson, S. Merideth, F. Kontos, N. Fricchione, G. L. Smith, F. A. Gen Hosp Psychiatry 2020

Akinetic mutism
Covid-19
Delirium
Encephalopathy
SARS-CoV-2

Prevalence of delirium in intensive care patients and association with sedoanalgesia, severity and mortality Bastos, A. S. Beccaria, L. M. Silva, D. C. D. Barbosa, T. P. Revista gaucha de enfermagem 2020

adult
article
checklist
controlled study
female
human
intensive care psychosis
intensive care unit
major clinical study
male
mortality
prevalence
quantitative analysis
Richmond Agitation Sedation Scale
sedation
clonidine
fentanyl
midazolam

Antipsychotics and the Risk of Mortality or Cardiopulmonary Arrest in Hospitalized Adults Basciotta, M. Zhou, W. Ngo, L. Donnino, M. Marcantonio, E. R. Herzig, S. J. J Am Geriatr Soc 2020

antipsychotics
mortality
pharmacoepidemiology

Comprehensive analysis of in-hospital delirium after major surgical oncology procedures: A population-based study Bandini, M. Marchioni, M. Preisser, F. Nazzani, S. Tian, Z. Graefen, M. Montorsi, F. Saad, F. Shariat, S. F. Schips, L. Briganti, A. Karakiewicz, P. I. Can Urol Assoc J 2020

adult
Cinahl
clinical trial
comorbidity
comparative effectiveness
delirium
drug therapy
Embase
female
geriatric patient
geriatrics
human
intensive care unit
male
Medline
meta analysis
null result
observational study
prevention
qualitative analysis
randomized controlled trial (topic)
review
sample size
systematic review
treatment duration
Web of Science
melatonin

Sepsis Associated Delirium Atterton, B. Paulino, M. C. Povoa, P. Martin-Loeches, I. Medicina (Kaunas) 2020

adult
Cinahl
clinical trial
comorbidity
comparative effectiveness
delirium
drug therapy
Embase
female
geriatric patient
geriatrics
human
intensive care unit
male
Medline
meta analysis
null result
observational study
prevention
qualitative analysis
randomized controlled trial (topic)
review
sample size
systematic review
treatment duration
Web of Science
melatonin

Melatonin for delirium prevention in acute medically ill, and perioperative geriatric patients Asleson, D. R. Chiu, A. W. Aging Medicine 2020

adult
Cinahl
clinical trial
comorbidity
comparative effectiveness
delirium
drug therapy
Embase
female
geriatric patient
geriatrics
human
intensive care unit
male
Medline
meta analysis
null result
observational study
prevention
qualitative analysis
randomized controlled trial (topic)
review
sample size
systematic review
treatment duration
Web of Science
melatonin

The short- And long-term outcomes of esophagectomy for esophageal cancer in patients older than 75 years Aoyama, T. Hara, K. Kazama, K. Atsumi, Y. Tamagawa, H. Tamagawa, A. MacHida, D. Komori, K. Maezawa, Y. Kano, K. Hashimoto, I. Oshima, T. Murakawa, M. Numata, M. Yukawa, N. Masuda, M. Rino, Y. Anticancer Research 2020

antineoplastic agent
abdominal abscess
adult
age
aged
anastomosis leakage
anastomosis stenosis
article
cancer patient
cancer prognosis
cancer surgery
cancer survival
cardiovascular disease
clinical evaluation
clinical outcome
comparative study
deep vein thrombosis
esophagus cancer
esophagus resection
female
human
long term survival
major clinical study
male
morbidity
neoadjuvant chemotherapy
overall survival
pneumonia
postoperative delirium
postoperative hemorrhage
postoperative ileus
priority journal
recurrence free survival
retrospective study
short term survival
surgical infection
surgical mortality
survival analysis
survival rate

National French survey of COVID-19 symptoms in people aged 70 and over Annweiler, C. Sacco, G. Salles, N. Aquino, J. P. Gautier, J. Berrut, G. Guérin, O. Gavazzi, G. Clin Infect Dis 2020
COVID-19: ICU delirium management during SARS-CoV-2 pandemic-pharmacological considerations Andrews, L. J. Benken, S. T. Crit Care 2020

Betacoronavirus
Coronavirus Infections
Delirium
Humans
Intensive Care Units
Pandemics
Pneumonia, Viral
SARS Virus

The Intersection of Architecture/Medicine/Quality and the Clinical Nurse Specialist: Designing for the Prevention of Delirium Anderson, D. C. Jacoby, S. R. Scruth, E. A. Clinical nurse specialist CNS 2020
The Agents Intervening against Delirium in the Intensive Care Unit-Trial (AID-ICU trial):- a detailed statistical analysis plan Andersen-Ranberg, N. Poulsen, L. M. Perner, A. Wetterslev, J. Mathiesen, O. Mortensen, C. B. Estrup, S. Ebdrup, B. H. Hästbacka, J. Citerio, G. Caballero, J. Morgan, M. P. G. Oxenbøll-Collet, M. Weber, S. O. Andreasen, A. S. Bestle, M. H. Pedersen, H. B Acta Anaesthesiol Scand 2020
A systematic review of the overlap of fluid biomarkers in delirium and advanced cancer-related syndromes Amgarth-Duff, I. Hosie, A. Caplan, G. Agar, M. BMC Psychiatry 2020

Advanced cancer
Biomarker
Delirium
Review

Toward best practice methods for delirium biomarker studies: An international modified Delphi study Amgarth-Duff, I. Hosie, A. Caplan, G. Agar, M. Int J Geriatr Psychiatry 2020

consensus
guidelines
methodology
pathophysiology

Preoperative cognitive dysfunction in older elective noncardiac surgical patients in South Africa Amado, L. A. Perrie, H. Scribante, J. Ben-Israel, K. A. Br J Anaesth 2020

Mini-Cog
aged
clock drawing test
cognitive dysfunction
neurocognitive dysfunction
perioperative
preoperative

The etiology and age-related properties of patients with delirium in coronary intensive care unit and its effects on inhospital and follow up prognosis Altay, S. Gürdoğan, M. Kaya, Ç Kardaş, F. Zeybey, U. Çakir, B. Ebik, M. Demir, M. Ideggyogy Sz 2020

delirium in coronary intensive care unit
etiology
follow-up mortality
inhospital mortality

A Unique Presentation of Delirium in a Patient with Otherwise Asymptomatic COVID-19 Alkeridy, W. A. Almaghlouth, I. Alrashed, R. Alayed, K. Binkhamis, K. Alsharidi, A. Liu-Ambrose, T. J Am Geriatr Soc 2020

Covid-19
atypical
delirium
fall
outbreak

Postoperative delirium after abdominal aortic surgery: after ICU discharge surveillance should extend to the surgical ward Alessandri, F. Bilotta, F. Minerva Anestesiol 2020
The prevalence of emergence delirium and its associated factors among children at a postoperative unit: A retrospective cohort at a Middle Eastern hospital Aldakhil, S. K. Salam, M. Albelali, A. A. Alkanhal, R. M. Alnemer, M. J. Alatassi, A. Saudi J Anaesth 2020

Anesthesia
Precedex
Watcha
Yale
anxiety
delirium
surgery

Optimal goal of management of delirium in end-of-life cancer care Akechi, T. Lancet Oncol 2020
Multiple Peri-Operative Complications are Associated with Reduced Long Term Amputation Free Survival Following Revascularisation for Lower Limb Peripheral Artery Disease: A Population Based Linked Data Study Aitken, S. J. Randall, D. A. Noguchi, N. Blyth, F. M. Naganathan, V. Eur J Vasc Endovasc Surg 2020

Aged
Aged, 80 and over
Amputation
Databases, Factual
Female
Humans
Limb Salvage
Lower Extremity/ blood supply
Male
Middle Aged
New South Wales/epidemiology
Peripheral Arterial Disease/diagnosis/mortality/ surgery
Postoperative Complications/diagnosis/ epidemiology/mortality
Progression-Free Survival
Retrospective Studies
Risk Assessment
Risk Factors
Time Factors
Vascular Surgical Procedures/ adverse effects/mortality
Data linkage
Peripheral artery disease
Post-operative complications
Prognosis

Neurological manifestations and complications of COVID-19: A literature review Ahmad, I. Rathore, F. A J Clin Neurosci 2020

Clinical features
Coronavirus
Delirium
Encephalitis
Headache
Neurology
Stroke

The role of suvorexant in the prevention of delirium during acute hospitalization: A systematic review Adams, A. D. Pepin, M. J. Brown, J. N. J Crit Care 2020

Belsomra
Confusion
Critical care
Critically ill
Neurocognitive disorders
Orexin receptor antagonist
and the authors have no conflicts of interest to declare.

Quetiapine for delirium prophylaxis in high-risk critically ill patients Abraham, M. P. Hinds, M. Tayidi, I. Jeffcoach, D. R. Corder, J. M. Hamilton, L. A. Lawson, C. M. Bollig, R. W. Heidel, R. E. Daley, B. J. Taylor, J. E. McMillen, J. C. Surgeon 2020

Delirium
Intensive care unit
Quetiapine
Surgery

Comparing outcomes after peripheral nerve block versus general anesthesia for lower extremity amputation: a nationwide exploratory retrospective cohort study in Japan Abe, H. Sumitani, M. Matsui, H. Aso, S. Inoue, R. Fushimi, K. Uchida, K. Yasunaga, H. Yamada, Y. Reg Anesth Pain Med 2020

lower extremity
postoperative pain
surgical outcome

Development of delirium: Association with old age, severe burns, and intensive care Abdelrahman, I. Vieweg, R. Irschik, S. Steinvall, I. Sjöberg, F. Elmasry, M. Burns 2020

Burns
Delirium
Inflammation
Intensive care
Old age
Wound care procedures

Factors Associated With Postoperative Confusion and Prolonged Hospital Stay Following Deep Brain Stimulation Surgery for Parkinson Disease Abboud, H. Genc, G. Saad, S. Thompson, N. Oravivattanakul, S. Alsallom, F. Yu, X. X. Floden, D. Gostkowski, M. Ahmed, A. Ezzeldin, A. Marouf, H. M. Mansour, O. Y. Fernandez, H. H. Neurosurgery 2020

Dbs
Deep-brain stimulation
Hospital stay
Parkinson disease
Postoperative delirium
Postoperative outcomes

Mortality and complications after emergency laparotomy in patients above 80 years Aakre, E. K. Ulvik, A. Hufthammer, K. O. Jammer, I. Acta Anaesthesiol Scand 2020

elderly
frail
surgery

Evaluation of an emergency department falls pathway for older people: A patient chart review O' Keeffe A O' Grady S Cronin, F. Dolan, C. O' Hea A O' Shea KL Naughton, C. Int Emerg Nurs 2020
Rapid in-person cognitive screening in the preoperative setting: Test considerations and recommendations from the Society for Perioperative Assessment and Quality Improvement (SPAQI) Arias, F. Wiggins, M. Urman, R. D. Armstrong, R. Pfeifer, K. Bader, A. M. Libon, D. J. Chopra, A. Price, C. C. Journal of Clinical Anesthesia 2020

anesthesiology
attention
clock drawing test
cognition
cognitive defect
dementia
geriatrics
human
language
memory
methodology
Mini Mental State Examination
neuropsychology
peer review
perioperative monitoring
primary medical care
priority journal
psychometry
review
sensitivity and specificity
telephone interview
total quality management
workflow

Updated nomenclature of delirium and acute encephalopathy: statement of ten Societies Slooter, A. J. C. Otte, W. M. Devlin, J. W. Arora, R. C. Bleck, T. P. Claassen, J. Duprey, M. S. Ely, E. W. Kaplan, P. W. Latronico, N. Morandi, A. Neufeld, K. J. Sharshar, T. MacLullich, A. M. J. Stevens, R. D. Intensive Care Medicine 2020

acute brain disease
article
delirium
human
nomenclature
organization

Nonsedation or Light Sedation in Critically Ill, Mechanically Ventilated Patients Olsen, H. T. Nedergaard, H. K. Strøm, T. Oxlund, J. Wian, K. A. Ytrebø, L. M. Kroken, B. A. Chew, M. Korkmaz, S. Lauridsen, J. T. Toft, P. The New England journal of medicine 2020

NCT01967680
acute kidney failure
adult
agitation
APACHE
article
artificial ventilation
coma
controlled study
critically ill patient
delirium
female
human
intensive care unit
major clinical study
male
medical research
mortality
multicenter study
outcome assessment
randomization
randomized controlled trial
sedation
thromboembolism
ventilated patient

Ketamine Safety and Use in the Emergency Department for Pain and Agitation/Delirium: A Health System Experience Mo, H. Campbell, M. J. Fertel, B. S. Lam, S. W. Wells, E. J. Casserly, E. Meldon, S. W. The western journal of emergency medicine 2020

adult
adverse drug reaction
agitation
analgesia
article
clinical evaluation
comorbidity
delirium
dissociation
drug safety
drug therapy
emergency ward
endotracheal intubation
female
human
incidence
major clinical study
male
medical record review
nasal cannula
non rebreathing valve
patient information
pharmacokinetics
retrospective study
sedation
side effect
ketamine

Impact of skeletal muscle mass on postoperative delirium in patients undergoing free flap repair after oral cancer resection Makiguchi, T. Yamaguchi, T. Nakamura, H. Ogawa, M. Harimoto, N. Shirabe, K. Yokoo, S. Journal of plastic surgery and hand surgery 2020

adult
article
cancer patient
cancer surgery
controlled study
diet therapy
exercise
female
free tissue graft
human
insomnia
major clinical study
male
mouth cancer
muscle mass
positron emission tomography-computed tomography
postoperative delirium
preoperative evaluation
prevention
risk assessment
risk factor
sarcopenia
skeletal muscle
surgery
third lumbar vertebra
albumin
endogenous compound

Identifying delirium in Parkinson disease: A pilot study Lawson, R. A. Richardson, S. J. Yarnall, A. J. Burn, D. J. Allan, L. M. International Journal of Geriatric Psychiatry 2020

aged
article
clinical article
consensus
controlled study
delirium
DSM-5
female
frailty
hospital patient
hospitalization
human
incidence
male
Parkinson disease
pilot study
prevalence
vignette

Presurgical cognitive impairment is associated with postoperative delirium and postoperative cognitive dysfunction Knaak, C. Brockhaus, W. R. Spies, C. Borchers, F. Piper, S. K. Radtke, F. M. Lachmann, G. Minerva anestesiologica 2020

aged
anesthesia
article
controlled study
Diagnostic and Statistical Manual of Mental Disorders
female
follow up
human
major clinical study
male
postoperative cognitive dysfunction
postoperative delirium
randomization
randomized controlled trial

The effects of elective aortic repair, colorectal cancer surgery and subsequent postoperative delirium on long-term quality of life, cognitive functioning and depressive symptoms in older patients Janssen, T. L. de Vries, J. Lodder, P. Faes, M. C. Ho, G. H. Gobardhan, P. D. van der Laan, L. Aging & mental health 2020

abdominal aortic aneurysm
abdominal surgery
adult
aortic reconstruction
article
cancer patient
cancer surgery
cognition
cohort analysis
colorectal cancer
controlled study
depression
elective surgery
female
human
major clinical study
male
Mini Mental State Examination
outcome assessment
postoperative delirium
postoperative period
prospective study
psychological well-being
quality of life
questionnaire
risk factor
surgery
surgical patient
World Health Organization

American Society for Enhanced Recovery and Perioperative Quality Initiative Joint Consensus Statement on Postoperative Delirium Prevention Hughes, C. G. Boncyk, C. S. Culley, D. J. Fleisher, L. A. Leung, J. M. McDonagh, D. L. Gan, T. J. McEvoy, M. D. Miller, T. E. Anesthesia and analgesia 2020

adult
adverse outcome
article
cognitive defect
complication
Delphi study
high risk population
hospital readmission
human
institutionalization
length of stay
major surgery
outcome assessment
physician
postoperative delirium
prevention
skill

Healthcare professionals' reports of cancer pain cues among older people with delirium: a qualitative-quantitative content analysis Graham, C. A. Chaves, G. Harrison, R. Gauthier, L. R. Nissim, R. Zimmermann, C. Chan, V. Rodin, G. Stevens, B. Gagliese, L. Journal of pain and symptom management 2020

adult
article
bivariate analysis
cancer pain
content analysis
controlled study
data analysis software
delirium
demography
doctor nurse relation
female
genetic transcription
human
informed consent
interview
major clinical study
male
pain assessment
quantitative analysis
self report

Preoperative Cognitive Abnormality, Intraoperative Electroencephalogram Suppression, and Postoperative Delirium: A Mediation Analysis Fritz, B. A. King, C. R. Ben Abdallah, A. Lin, N. Mickle, A. M. Budelier, T. P. Oberhaus, J. Park, D. Maybrier, H. R. Wildes, T. S. Avidan, M. S. Apakama, G. Aranake-Chrisinger, A. Bolzenius, J. Burton, J. Cui, V. Emmert, D. A. Goswami, S. Graetz, T. J. G Anesthesiology 2020

adult
aging
article
complication
convalescence
effect size
electroencephalogram
electroencephalography
female
general anesthesia
human
incidence
interview
major clinical study
male
medical record review
mentally disabled person
postoperative delirium
preoperative evaluation
randomization
randomized controlled trial
secondary analysis
surgery
university hospital

Delirium screening and mortality in patients with dementia admitted to acute hospitals Codling, D. Hood, C. Bassett, P. Smithard, D. Crawford, M. J. Aging & mental health 2020

aged
article
cognitive defect
controlled study
England
female
human
major clinical study
male
mortality
multicenter study
secondary analysis
very elderly
Wales

Do Neuroleptics Still Have a Role in Patients With Delirium? Nikooie, R. Oh, E. S. Zhang, A. Robinson, K. A. Needham, D. M. Annals of internal medicine 2020

adult
article
delirium
human
neuroleptic agent

Randomized clinical trial of intraoperative dexmedetomidine to prevent delirium in the elderly undergoing major non-cardiac surgery Li, C. J. Wang, B. J. Mu, D. L. Hu, J. Guo, C. Li, X. Y. Ma, D. Wang, D. X. British Journal of Surgery 2020

ChiCTRIPR15007654
injection device
Slgo
cisatracurium
dexamethasone
dexmedetomidine
flurbiprofen axetil
methylprednisolone
midazolam
morphine
parecoxib
propofol
sufentanil
adult
aged
all cause mortality
article
Barthel index
bradycardia
Child Pugh score
confusion assessment method
controlled study
delirium
double blind procedure
drug infusion
drug safety
extubation
female
follow up
human
hypertension
hypotension
incidence
loading drug dose
major clinical study
male
mental disease assessment
middle aged
Mini Mental State Examination
nausea and vomiting
numeric rating scale
observational study
perioperative period
priority journal
randomized controlled trial
risk factor

Risk factors for adverse drug reactions in older inpatients of geriatric wards at admission: Multicenter study Kojima, T. Matsui, T. Suzuki, Y. Takeya, Y. Tomita, N. Kozaki, K. Kuzuya, M. Rakugi, H. Arai, H. Akishita, M. Geriatrics and Gerontology International 2020

albumin
creatinine
adverse drug reaction
aged
albumin blood level
article
bleeding
cohort analysis
creatinine blood level
dehydration
delirium
disease association
dizziness
edema
electrolyte disturbance
endocrine disease
female
functional status
gastrointestinal disease
geriatric assessment
geriatric hospital
heart arrhythmia
heart failure
hematologic disease
hospital admission
human
hyperglycemia
hypoglycemia
Japan
kidney failure
length of stay
liver disease
major clinical study
male
medical record
multicenter study
neurologic disease
observational study
priority journal
rash
respiratory failure
retrospective study
risk assessment
risk factor
sedation
symptom
very elderly

Real-world effectiveness of ramelteon and suvorexant for delirium prevention in 948 patients with delirium risk factors Hatta, K. Kishi, Y. Wada, K. Takeuchi, T. Hashimoto, N. Suda, K. Taira, T. Tsuchida, K. Ohmori, T. Akizuki, N. Nishio, Y. Nakanishi, Y. Usui, C. Kurata, A. Horikawa, N. Eguchi, H. Ito, S. Muto, H. Nakamura, H. Uchimura, N. Journal of Clinical Psychiatry 2020

corticosteroid derivative
opiate derivative
ramelteon
suvorexant
acute disease
aged
article
clinical outcome
clinical practice
consultation
delirium
drug effect
drug efficacy
DSM-5
elective surgery
female
hospitalization
human
incidence
insomnia
major clinical study
male
mental health service
multicenter study
observational study
outcome assessment
patient decision making
physiatrist
prescription
priority journal
prospective study
risk assessment
risk factor
somnolence

Independent Association Between Type of Intraoperative Blood Transfusion and Postoperative Delirium After Complex Spinal Fusion for Adult Deformity Correction Elsamadicy, A. A. Adil, S. M. Charalambous, L. Drysdale, N. Koo, A. B. Lee, M. Kundishora, A. J. Camara-Quintana, J. Kolb, L. Laurans, M. Abbed, K. Karikari, I. O. Spine 2020

adult
age
article
bleeding
blood transfusion
cohort analysis
comorbidity
complication
controlled study
female
health care cost
hospitalization
human
incidence
major clinical study
male
medical record
outcome assessment
patient care
postoperative delirium
retrospective study
spine fusion
spine malformation
surgery

Practices related to assessment of sedation, analgesia and delirium among critical care pediatricians in Brazil Colleti Junior, J. Araujo, O. R. Andrade, A. B. Carvalho, W. B. Einstein (Sao Paulo, Brazil) 2020

analgesia
article
Brazil
child
delirium
demography
e-mail
human
patient comfort
pediatric intensive care unit
pediatrician
questionnaire
Ramsay Sedation Scale
sedation

Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Chen, N. Zhou, M. Dong, X. Qu, J. Gong, F. Han, Y. Qiu, Y. Wang, J. Liu, Y. Wei, Y. Xia, J. Yu, T. Zhang, X. Zhang, L. The Lancet 2020

adult
age
article
China
chronic disease
clinical feature
confusion
Coronavirus disease 2019
Coronavirus infection
coughing
descriptive research
disease exacerbation
dyspnea
epidemiological data
exposure
female
fever
follow up
headache
human
major clinical study
male
marketing
medical history
multiple organ failure
myalgia
nausea and vomiting
pneumothorax
priority journal
real time polymerase chain reaction
respiratory distress
retrospective study
sea food
sore throat
thorax pain
virus detection
virus pneumonia

Association between postoperative delirium and mortality in elderly patients undergoing hip fractures surgery: a meta-analysis Bai, J. Liang, Y. Zhang, P. Liang, X. He, J. Wang, J. Wang, Y. Osteoporosis International 2020

article
disease association
DSM-III
DSM-IV
follow up
hip fracture
hip surgery
hospital mortality
human
incidence
perioperative period
postoperative delirium
postoperative period
prevalence
priority journal
scoring system
surgical mortality
surgical risk
systematic review

Impact of frailty on short-term outcomes in patients undergoing transsphenoidal pituitary surgery Asemota, A. O. Gallia, G. L. Journal of Neurosurgery 2020

acute heart infarction
acute kidney failure
adult
aged
article
Black person
brain hematoma
brain hemorrhage
brain infarction
cerebrospinal fluid rhinorrhea
Charlson Comorbidity Index
cohort analysis
comorbidity
consciousness disorder
deep vein thrombosis
delirium
diabetes insipidus
diplopia
epistaxis
female
frailty
Hispanic
human
hypernatremia
hyperosmolality
hypertension
hyponatremia
hypoosmolality
hypophysis tumor
iatrogenic disease
inappropriate vasopressin secretion
length of stay
lowest income group
lung embolism
lung insufficiency
major clinical study
male
medicaid
medicare
meningitis
mental health
middle aged
mortality rate
ophthalmoplegia
postoperative nausea and vomiting
priority journal
reoperation
strabismus
transsphenoidal hypophysectomy
treatment outcome
visual field defect

Randomised controlled trial to investigate the relationship between mild hypercapnia and cerebral oxygen saturation in patients undergoing major surgery Wong, C. Churilov, L. Cowie, D. Tan, C. O. Hu, R. Tremewen, D. Pearce, B. Pillai, P. Karalapillai, D. Bellomo, R. Weinberg, L. BMJ Open 2020

delirium
hypercapnia
oximetry
respiration, artificial
spectroscopy, near infrared

Establishment and validation of a delirium prediction model for neurosurgery patients in intensive care Wang, J. Ji, Y. Wang, N. Chen, W. Bao, Y. Qin, Q. Ma, C. Xiao, Q. Li, S. Int J Nurs Pract 2020

delirium
neurosurgery
nursing
prediction model
risk factors

Early mobilisation after transfemoral transcatheter aortic valve implantation: results of the MobiTAVI trial Vendrik, J. Vlastra, W. van Mourik, M. S. Delewi, R. Beijk, M. A. Lemkes, J. Wykrzykowska, J. J. de Winter, R. J. Henriques, J. S. Piek, J. J. Vis, M. M. Koch, K. T. Baan, J., Jr. Neth Heart J 2020

Ambulation
Early mobilisation
Percutaneous valve
Safety protocol
Transfemoral transcatheter aortic valve implantation
Vascular complications

Influence of sedation on delirium recognition in critically ill patients: A multinational cohort study van den Boogaard, M. Wassenaar, A. van Haren, F. M. P. Slooter, A. J. C. Jorens, P. G. van der Jagt, M. Simons, K. S. Egerod, I. Burry, L. D. Beishuizen, A. Pickkers, P. Devlin, J. W. Aust Crit Care 2020

Assessment
Cam-icu
Delirium
Icdsc
Intensive care
Sedation
NCT02518646
adult
article
checklist
clinical evaluation
cohort analysis
controlled study
critically ill patient
female
human
intensive care psychosis
intensive care unit
major clinical study
male
multicenter study
nurse
prospective study
Richmond Agitation Sedation Scale
secondary analysis

Intraoperative reduction of vasopressors using processed electroencephalographic monitoring in patients undergoing elective cardiac surgery: a randomized clinical trial Sponholz, C. Schuwirth, C. Koenig, L. Hoyer, H. Coldewey, S. M. Schelenz, C. Doenst, T. Kortgen, A. Bauer, M. J Clin Monit Comput 2020

Adverse events
Cardiac anesthesia
Catecholamines
Neuromonitoring

Enhanced rehabilitation and care models for adults with dementia following hip fracture surgery Smith, T. O. Gilbert, A. W. Sreekanta, A. Sahota, O. Griffin, X. L. Cross, J. L. Fox, C. Lamb, S. E. Cochrane Database Syst Rev 2020
Prospective Evaluation of Delirium in Geriatric Patients Undergoing Emergency General Surgery Saljuqi, A. T. Hanna, K. Asmar, S. Tang, A. Zeeshan, M. Gries, L. Ditillo, M. Kulvatunyou, N. Castanon, L. Joseph, B. J Am Coll Surg 2020
Predisposing and Precipitating Factors Associated With Postoperative Delirium in Patients Undergoing Cardiac Surgery at a Veterans Affairs Medical Center: A Pilot Retrospective Analysis Russell, M. D. Pinkerton, C. Sherman, K. A. Ebert, T. J. Pagel, P. S. J Cardiothorac Vasc Anesth 2020

Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition
cardiac surgery complications
cardiopulmonary bypass
delirium
geriatrics

Dopaminergic Hyperactivity in Neurological Patients with Delirium Ramirez-Bermudez, J. Perez-Neri, I. Montes, S. Nente, F. Ramirez-Abascal, M. Carrillo-Mezo, R. Perez-Esparza, R. Soto-Hernandez, J. L. Espinola-Nadurille, M. Bayliss, L. De Jesus Flores Rivera, J. Rios, C. Arch Med Res 2020

Autoimmune limbic encephalitis
Confusional state
Delirium
Dopamine
Homovanillic acid
Neuropsychiatry

Effects of intravenous and mask induction on post-operative emergence delirium in pediatric patients undergoing tonsillectomy with or without adenoidectomy Peker, K. Polat, R. Ir J Med Sci 2020

Intravenous induction
Mask induction
Pediatric emergence delirium
adenoidectomy
anesthesia induction
article
cannula
child
controlled study
emergence agitation
female
human
incidence
leg
major clinical study
male
operating room
pediatric anesthesia
pediatric patient
postoperative pain
preschool child
prospective study
randomized controlled trial
recovery room
remission
single blind procedure
surgery
tonsillectomy
university hospital
vascular access
nitrous oxide
oxygen
sevoflurane

Safety and Tolerability of Rapid Administration Undiluted Levetiracetam Morgan, O. Medenwald, B. Neurocrit Care 2020

Anticonvulsants
Humans
Intravenous

New use of psychotropic medication after hospitalization among people with dementia Mollers, T. Perna, L. Stocker, H. Ihle, P. Schubert, I. Schottker, B. Frolich, L. Brenner, H. Int J Geriatr Psychiatry 2020

claims data
dementia
hospitalization
psychotropic medication

A logistic regression analysis comparing minimalistic approach and intubation anaesthesia in patients undergoing transfemoral transcatheter aortic valve replacement Maier, A. Hammerich, B. Humburger, F. Brieschal, T. Heidt, T. Bothe, W. Schrofel, H. Kaier, K. Zehender, M. Reinohl, J. Bode, C. von Zur Muhlen, C. Stachon, P. PLoS One 2020
Anticipating Postoperative Delirium During Burst Suppression Using Electroencephalography Ma, O. Crepeau, A. Z. Dutta, A. Bliss, D. IEEE Trans Biomed Eng 2020

adult
article
brain injury
clinical article
complication
cooling
electroencephalography
female
heart arrest
heart surgery
human
hypothermia
incidence
male
postoperative delirium
prognosis
reperfusion
surgery
surgical technique
warming

Can haloperidol prophylaxis reduce the incidence of delirium in critically ill patients in intensive care units? A systematic review and meta-analysis Lin, P. Zhang, J. Shi, F. Liang, Z. A. Heart Lung 2020

Delirium
Haloperidol
Intensive care
Meta-analysis
Randomized clinical trial

Benzodiazepines for treatment of patients with delirium excluding those who are cared for in an intensive care unit Li, Y. Ma, J. Jin, Y. Li, N. Zheng, R. Mu, W. Wang, J. Si, J. H. Chen, J. Shang, H. C. Cochrane Database Syst Rev 2020
Delirium prevalence and prevention in patients with acute brain injury: A prospective before-and-after intervention study Larsen, L. K. Moller, K. Petersen, M. Egerod, I. Intensive Crit Care Nurs 2020

Brain injuries
Critical care
Critical care nursing
Delirium
Intensive care units
Neuroscience nursing
Prevention

Postoperative anaemia might be a risk factor for postoperative delirium and prolonged hospital stay: A secondary analysis of a prospective cohort study Kunz, J. V. Spies, C. D. Bichmann, A. Sieg, M. Mueller, A. PLoS One 2020
Development of a Simple and Practical Delirium Screening Tool for Use in Surgical Wards Kubota, K. Suzuki, A. Ohde, S. Yamada, U. Fujitani, I. Koitabashi, A. J Nurs Res 2020

adult
area under the curve
article
bootstrapping
controlled study
delirium
diagnostic accuracy
diagnostic test accuracy study
disorientation
female
hallucination
hospital patient
human
major clinical study
male
medical record
nurse
receiver operating characteristic
restlessness
retrospective study
sensitivity and specificity
somnolence
surgical ward

Psychometric evaluation of the family caregiver ICU delirium knowledge questionnaire Krewulak, K. D. Bull, M. J. Ely, E. W. Stelfox, H. T. Fiest, K. M. BMC Health Serv Res 2020

Critical care
Delirium prevention and management
Family caregivers
Intensive care unit
adult
article
caregiver
content validity
controlled study
critically ill patient
Cronbach alpha coefficient
cross-sectional study
delirium
face validity
female
human
intensive care unit
internal consistency
major clinical study
male
multidisciplinary team
nurse
path analysis
questionnaire
risk factor

The Impact of Acute Kidney Injury in the Perioperative Period on the Incidence of Postoperative Delirium in Patients Undergoing Coronary Artery Bypass Grafting-Observational Cohort Study Kotfis, K. Slozowska, J. Listewnik, M. Szylinska, A. Rotter, I. Int J Environ Res Public Health 2020

Aki
Cabg
Gfr
Kdigo
Pod
acute kidney injury
creatinine
delirium
glomerular filtration rate

Delirium point prevalence studies in inpatient settings: A systematic review and meta-analysis Koirala, B. Hansen, B. R. Hosie, A. Budhathoki, C. Seal, S. Beaman, A. Davidson, P. M. J Clin Nurs 2020

delirium
inpatient
meta-analysis
point prevalence
systematic review
adult
benchmarking
dementia
female
high risk patient
hospital patient
human
male
patient care
prevalence
quality improvement study
review
risk assessment
sample siz

Validity and Reliability of the Memorial Delirium Assessment Scale-Thai Version (MDAS-T) for Assessment of Delirium in Palliative Care Patients Klankluang, W. Pukrittayakamee, P. Atsariyasing, W. Siriussawakul, A. Chanthong, P. Tongsai, S. Tayjasanant, S. Oncologist 2020

Delirium
Mdas
Palliative care
Screening
Sensitivity and specificity
Validity and reliability
adult
article
construct validity
content validity
controlled study
correlation coefficient
Cronbach alpha coefficient
distress syndrome
DSM-5
exploratory factor analysis
female
gold standard
human
intensive care unit
internal consistency
interrater reliability
major clinical study
male
palliative therapy
principal component analysis
receiver operating characteristic
sensitivity and specificity

The Impact of an Attending Intensivist on the Clinical Outcomes of Patients Admitted to the Cardiac Surgical Intensive Care Unit after Coronary Artery Bypass Grafting Kim, D. J. Sohn, B. Kim, H. Chang, H. W. Lee, J. H. Kim, J. S. Lim, C. Park, K. H. Korean J Thorac Cardiovasc Surg 2020

Coronary artery bypass grafting
Critical care
Intensive care unit staffing
Intensivist
Postoperative complications

Working Collaboratively: Outcomes of Geriatrician Input in Older Patients Undergoing Emergency Laparotomy in a District General Hospital Khan, K. A. Subramanian, T. Richters, M. Mubarik, A. Saad Abdalla Al-Zawi, A. Thorn, C. C. Chalstrey, S. Gunasekera, S. Cureus 2020

ageing & frailty
cepod
cognitive impairment
elderly patients
emergency laparotomy
geriatric surgical liaison
length of stay
perioperative care

Postoperative delirium: the findings from a multidisciplinary survey Jin, Z. Rahman, A. Pattnaik, S. Smith, M. Psychogeriatrics 2020

education
hypoactive delirium
management
postoperative delirium
screening
acute psychosis
adult
article
complication
diagnostic error
education
human
mortality risk
multidisciplinary team
postoperative delirium
prognosis
surgery

Postoperative delirium after reconstructive surgery for oral tumor: a retrospective clinical study Ishibashi-Kanno, N. Takaoka, S. Nagai, H. Okubo-Sato, M. Fukuzawa, S. Uchida, F. Yamagata, K. Yanagawa, T. Bukawa, H. Int J Oral Maxillofac Surg 2020

Delirium
Oral tumor
Postoperative delirium
Reconstructive surgery

Joining Forces against Delirium - From Organ-System Care to Whole-Human Care Inouye, S. K. N Engl J Med 2020

Aged
Clinical Protocols
Coronary Artery Bypass/adverse effects
Delirium/diagnosis/etiology/ prevention & control
Diagnostic Errors
Humans
Iatrogenic Disease/ prevention & control
Male
Cinical practice
Evidence based practice
Frailty
Geriatric care
Health care cost
Health care delivery
Health care policy
Health care system
Health program
Hospital mortality
Human
Medicare
Priority journal
Reimbursement
Review
Vulnerable population

Incidence of and risk factors for postoperative delirium in older adult patients undergoing noncardiac surgery: a prospective study Iamaroon, A. Wongviriyawong, T. Sura-Arunsumrit, P. Wiwatnodom, N. Rewuri, N. Chaiwat, O. BMC Geriatr 2020

Collaborative approach
Incidence
Noncardiac surgery
Older adult patients
Postoperative delirium
Risk factors
aged
anesthesiologist
article
Barthel index
cognitive defect
complication
controlled study
DSM-5
female
geriatrician
hematocrit
high risk population
hospitalization
human
incidence
major clinical study
male
multidisciplinary team
perioperative period
peroperative complication
postoperative delirium
preoperative evaluation
prospective study
questionnaire
risk factor
surgery
univariate analysis
benzodiazepine
opiate

Delirium misdiagnosis risk in psychiatry: a machine learning-logistic regression predictive algorithm Hercus, C. Hudaib, A. R. BMC Health Serv Res 2020

Delirium
Input variables
Machine learning-logistic classifier
Misdiagnosis